CURRENT AND EMERGING CANCER DIAGNOSTIC TESTS Emerging Assays, and Companies Developing New Technologies and Products.
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1 CURRENT AND EMERGING CANCER DIAGNOSTIC TESTS Emerging Assays, and Companies Developing New Technologies and Products Table of Contents Major Current And Emerging Cancer Diagnostic Tests 1. Introduction 2. Tumor Marker Classification 3. ACTH 4. Alpha-Fetoprotein (AFP) 5. Beta-2 Microglobulin 6. CA 15-3/ CA CA Calcitonin 10. Carcinoembrionic Antigen (CEA) 11. Estrogen and Progesterone Receptors 12. Ferritin 13. Gastrin 14. Human Chorionic Gonadotropin (HCG) 15. Insulin 16. NSE 17. Occult Blood 18. PAP Smear/HPV 19. Prostatic Acid Phosphatase (PAP) 20. Prostate-Specific Antigen (PSA) 21. Squamous Cell Carcinoma Antigen (SCC) 22. T and B Lymphocytes 23. TdT 24. Thyroglobulin 25. Tissue Polypeptide Antigen (TPA) 26. Biochemical Tumor Markers - ADA - B-Protein - PNP - 5'-Nucleotidase 27. Oncogenes - Abl/abl-bcr - AIB1 - BCL-2 - BRCA1 - CD44
2 Table of Contents (continued) - C-fos - C-myb - C-myc - CYP-17 - Erb-B - HPC1 - N-myc - P40 - P51 - P53 - PIK3CA - PTI-1? Ras? Reg? Sis? Src 28. Polypeptide Growth Factors? Basic Fibroblast Growth Factor? Beta-TGF? Cachectin (TNT)? Calmodulin? ECFR? Nerve Growth Factor (NGF)? Epidermal Growth Factor (EGF)? Ornithine Decarboxylase? Transferrin? Transforming Growth Factor-Alpha 29. Ectopic Hormones 30. Colony Stimulating Factors 31. Lymphokines? Alpha-Interferon? B Cell Growth Factors? B Cell Growth Factor (BCGF)? Gamma-Interferon? Interleukin-1 (IL-1)? Macrophage Activating Factor 32. Immunohistochemical Stains 33. Emerging Tumor Markers? N-Acetylglucosamine? Actin? Alpha-Actin
3 Table of Contents (continued) - Antineuronal Antibodies - 7B2 - B Bax - BCD-F9 - BLCA-4 - Blood Group Antigens A,B,H - CA 50 - CA 72-4/TAG-72 - CA CA CA CAM 26 - CAR-3 - Cathepsin-D - Chromogranin A and B - Cluster 1 Antigen - Cluster-5/5A Antigen - CTA - CU18 - DR-70 - DU-PAN-2 - Endometrial Bleeding Associated Factor - Endostatin - Epithelial Membrane Antigen - Feulgen Hydrolysis - Fibronectin - FSH - (1->3)-L-fucosyltransferase - Gastrin-Releasing Peptide (GRP) - GDCFP-15 - Glucagon - Glycoamines - H23 - Her-2 - Human Carcinoma Antigen - HPA - HSP27 - Intermediate Filaments
4 Table of Contents (continued) - Cytokeratins/CK18/Cyfra Desmin - Gliofibrillary Acid Protein - Neurofilaments - Vimentin - KA 93 - Kinases - KP16D3 - LAI - Leukocyte Common Antigen - Lewis Antigens - Lysophosphatidic Acid (LPA) - Ma 695/Ma MABDF3 - MAG - ME1 - Minactivin - MN/CA9 - MSA - Mucin Cancer Antigen (MCA) - Multiple Tumor Suppressor 1 - Myosin - NEA NMP22 - OA Opiod Peptides - P-glycoprotein - Pancreatic Oncofetal Antigen (POA) - Placental Lactogen - PR92 - Proliferative Index, Ki-67 - Px - RB Inactivation/Deletion - Ret - SCCL Selectin - Sialic Acid - Sialyl SSEA-1/SLX
5 Table of Contents (continued) - SN10 - Somatostatin - TA-90 - TABA - Tachykinin - TAG 12 - TPS - Troponin - Tubulin - VCAM - VEGF - Villen Appendixes Appendix I: Major Universities and Research Centers Developing Cancer Diagnostic Technology and Applications
6 List of Tables Tumor Marker Classification ACTH Tests AFP Tests Beta-2 Microglobulin Tests CA 15-3/27.29 Tests CA 19-9 Tests CA 125 Tests Calcitonin Tests CEA Tests Estrogen Receptor Tests Progesterone Receptor Tests Ferritin Tests Gastrin Tests
7 List of Tables (continued) HCG Tests Insulin Tests NSE Tests Occult Blood Tests PAP Smear/HPV Tests PAP Tests PSA Tests Lymphocyte Subclassification Tests Biochemical Markers Potential Applications In Cancer Diagnosis Oncogenes Potential Applications In Cancer Diagnosis Oncogene Tests Growth Factors Potential Applications In Cancer Diagnosis
8 List of Tables (continued) Colony Stimulating Factors Potential Applications in Cancer Diagnosis Lymphokines Potential Applications In Cancer Diagnosis Immunohistochemical Stains Potential Applications in Cancer Diagnosis
Table of Contents. III. Major Current And Emerging Cancer Diagnostic Tests
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Created: April 2002 of Review: February 2004 of Review: June 2006 of Review: July 2007, St. Joseph s Healthcare went live with Meditech as of June18, 2007. of Review: August 2009 of Review: December 2011;