2011 International Conference of Inflammation, Cancer and Metabolic Disorders Program

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1 Friday, November 4 th, :00-09:30 Registration 09:30-09:40 Welcome & Opening Remarks Kenneth K. Wu, M.D., Ph.D. Fu-Tong Liu, M.D., Ph.D. Plenary Lecture I Chair: Kenneth K. Wu, M.D., Ph.D. 09:40-10:40 Dynamic Epigenetic Events Regulate the Expression of Immune Cell-derived Mediators during the Progression of Inflammatory Disease Steven L. Kunkel, Ph.D. University of Michigan Medical School, Ann Arbor, Michigan, USA Inflammation I Co-chair: Shie-Liang Hsieh, M.D., Ph.D. National Yang-Ming University, Taipei, Taiwan Tse-Hua Tan, Ph.D. 10:40-11:20 Roles of MAP4Ks and DUSPs in Lymphocyte Signaling, Inflammation and Human Diseases Tse-Hua Tan, Ph.D. 11:20-12:00 Environment and Immunity in Homeostasis and Disease: Role of the Aryl-hydrocarbon Receptor (AhR)-ligand Axis in Mast Cells Shau-Ku Huang, Ph.D. 12:00-12:15 Thrombomodulin Domains Attenuate Atherosclerosis by Inhibiting Thrombin-induced Endothelial Cell Activation (Poster No.46) 12:15-13:30 Lunch Hsi-Ju Wei 1

2 Cancer I 2011 International Conference of Inflammation, Co-chair: Ming-Zong Lai, Ph.D. Muh-Hwa Yang, M.D., Ph.D. National Yang-Ming University, Taipei, Taiwan 13:30-14:10 Innate Resistance, Inflammation, and Carcinogenesis Giorgio Trinchieri, M.D. National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA 14:10-14:50 Study of T cell Exhaustion in A Murine Model of Chronic Hepatitis B and Hepatocellular Carcinoma Mi-Hua Tao, Ph.D. 14:50-15:30 Cyclooxygnease-2-overexpressing Breast Cancer Cells Promote Cancer Progression via Multiple Autocrine and Paracrine Mechanisms Wen-Chun Hung, Ph.D. 15:30-15:45 Control of Cancer Cell COX-2 Expression and Invasiveness by Novel Tryptophan Metabolites (Poster No.03) Huei-Hsuan Cheng 15:45-16:00 IFIT2 Depletion Mediates through Atypical PKC Signaling to Enhance Epithelial Mesenchymal Transition, Motility, and Invasiveness in Oral Squamous Cell Carcinoma (Poster No.09) 16:00-16:20 Break Kuo-Chu Lai Metabolic Disorders I Co-chair: Wen-Chang Chang, Ph.D. Hua-Lin Wu, Ph.D. 16:20-17:00 Nuclear Receptor COUP-TFII in Energy Metabolism and Mesenchymal Stem Cell Differentiation Ming-Jer Tsai, Ph.D. Baylor College of Medicine, Houston, Texas, USA 2

3 17:00-17:40 Interplay between Lipid Inflammation and Metabolic Disease Yau-Sheng, Tsai, Ph.D. 17:40-17:55 Hematopoietic Heme Oxygenase-1 Haploinsufficiency Reduces High Fat Diet-induced Adipose Macrophage Infiltration and Insulin Resistance (Poster No.51) Jun-Yuan Huang 18:00~ Welcome Dinner 3

4 Saturday, November 5 th, 2011 Plenary Lecture II Chair: Lu-Hai Wang, Ph.D. 09:00-10:00 IL-6: All the Way to Therapy for Autoimmune Inflammatory Diseases 10:00-10:20 Break Tadamitsu Kishimoto, M.D., Ph.D. Osaka University, Osaka, Japan Inflammation II Co-chair: Shau-Ku Huang, Ph.D. Danny Ling Wang, Ph.D. 10:20-11:00 Crosstalk between Autophagy and Inflammasomes Augustine M. K. Choi, M.D. Brigham and Women s Hospital, Boston, Massachusetts, USA 11:00-11:40 Role of Cyclooxygenases in T Cell Development and Function Darryl C. Zeldin, M.D. National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA 11:40-11:55 JKAP/DUSP22 Inhibits TCR Signaling and Autoimmunity by Dephosphorylating Lck (Poster No.40) Ju-Pi Li 11:55-12:10 Hydrogen Sulfide Produced in Endothelial Cells is Enhanced under Shear Stress and it Contributes to Shear-induced Akt Signaling (Poster No.31) 12:10-13:30 Lunch Chang-Ting Chen 4

5 Metabolic Disorders II Co-chair: Lee-Young Chau, Ph.D. Chao Agnes Hsiung, Ph.D. 13:30-14:10 Inflammasome and Obesity-Associated Co-Morbidities Vishwa Deep Dixit, D.V.M., Ph.D. Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA 14:10-14:50 Genetics of Metabolic Syndrome-an Asian Perspective Lee-Ming Chuang, M.D., Ph.D. National Taiwan University Hospital, Taipei, Taiwan 14:50-15:05 Naa10p, an Epigenetic Regulator Linking Metabolism and Cancer (Poster No.53) Chung-Fan Lee Poster Session 15:20-18:30 Poster Presentation (Poster presenters should stay beside their posters from 15:20 to 18:30) 5

6 Sunday, November 6 th, 2011 Plenary Lecture III Chair: Fu-Tong Liu, M.D., Ph.D. 09:00-10:00 Two Uniquely Human Mechanisms of Chronic Inflammation, Involving Evolutionary Changes in Sialic Acid Biology 10:00-10:20 Break Ajit Varki, M.D. University of California, San Diego, La Jolla, California, USA Cancer II Co-chair: Min-Liang Kuo, Ph.D. National Taiwan University, Taipei, Taiwan Mi-Hua Tao, Ph.D. 10:20-11:00 Oncogene-driven Mouse Liver Cancers can be Differentially Influenced by Immune Mechanisms Robert H. Wiltrout, Ph.D. National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA 11:00-11:40 Potential Role of G9a in Cancer and Cancer Stem Cells 11:40-11:50 Poster Award Min-Liang Kuo, Ph.D. National Taiwan University, Taipei, Taiwan 11:50-12:00 Closing Remark 12:00-13:00 Lunch Kenneth K. Wu, M.D., Ph.D. 6

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