Line 1/IAPP- FWP Semi-Annual Report, S1: October March 2012 A B C D E F G H I J FORMER WORKER MEDICAL SCREENING PROGRAM SEMI-ANNUAL REPORT

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1 Project Name DOE Site Project PI Organization Line /IAPP- FWP Semi-Annual Report, S: October 2 - March 22 FORMER WORKER MEDICAL SCREENING PROGRAM SEMI-ANNUAL REPORT Cooperative Agreement Number Year/Semi-Annual Period Administrative Information Initial Institutional IRB Approval Date Continuing Institutional IRB Approval Date Initial CDOEIRB Approval Date Continuing CDOEIRB Approval Date Project Start Date Screening Start Date Estimated Eligible Population INITIAL SCREEN Outreach Information S S2 TTD Number of Potential Participants Attempted to Contact Directly (initial screen) 3,837 Mass mailings 3-year follow-up mailing- December 2 (n=277) Former Worker Medical Screening Program for the Iowa Army Ammunition Plant Iowa Army Ammunition Plant Lar Fuortes University of Iowa College of Public Health DE-FC-6EH62 Federal FY 22, Semi-Annual reporting period (S): October 2 - March 22 /5/2 2/2/2 /2/2 /2/22 8/5/2 3/2/2 7, of

2 Line /IAPP- FWP Semi-Annual Report, S: October 2 - March 22 Indicators of Interest in Initial Screen S S2 TTD Total Number of Respondents Interested and Eligible (initial screen),285 Number of Respondents Referred to (initial screen) 9 Participation Indicators (initial screen) S S2 TTD S S2 TTD S S2 TTD Total number of individuals received initial screening exam 6, ,33 S S2 TTD S S2 TTD Mean/Average Age at Exam (Male) Mean/Average Age at Exam (Female) Age Range (Male) Age Range (Female) Lab Studies/Findings (initial screen) Chest X-Rays (initial screen) S S2 TTD S S2 TTD S S2 TTD Total Number of Individuals Tested 6,9 89 7,79 Number with Suspected Asbestosis without pleural disease 2 25 Number with Suspected Asbestosis with pleural disease 2 3 Number with Suspected Asbestos-related pleural disease Number with Suspected Silicosis 2 of

3 Line /IAPP- FWP Semi-Annual Report, S: October 2 - March 22 Number with Suspected Mixed Dust Pneumoconiosis Number with Suspected Pneumoconiosis, not otherwise specified Number with Suspicious Lung Nodules, Nodes, Lesions (suspicious for cancer) 2 25 Pulmonary Function Tests (initial screen) S S2 TTD S S2 TTD S S2 TTD Total Number of Individuals Tested 6, ,296 Number with Restrictive Pattern Number with Obstructive Pattern Number with Mixed Pattern 9 2 Beryllium Sensitization/Disease Testing (initial screen) S S2 TTD S S2 TTD S S2 TTD Total Number of Individuals Tested 6,82 9 7,272 Number of Individuals with Abnormal BeLPT Number of Individuals with 2 Abnormal BeLPTs Number of Individuals with Abnormal and + Borderline BeLPTs 7 8 Audiograms S S2 TTD S S2 TTD S S2 TTD Total Number of Individuals Tested 87 Number of Individuals with Noise-induced hearing loss (NIHL) Number of Individuals with Supplemental Definition of Occupational NIHL 3 of

4 Line /IAPP- FWP Semi-Annual Report, S: October 2 - March 22 Follow-up Recommended S S2 TTD S S2 TTD S S2 TTD Potentially occupationally-related follow-up Non-occupationally-related follow-up RESCREEN- (3+ yrs since initial exam) Outreach Information S S2 TTD Number of Potential Participants Attempted to Contact Directly (rescreen-) 22,557 Indicators of Interest in Rescreen- S S2 TTD Total Number of Respondents Interested and Eligible (rescreen-) 2 78 Number of Respondents Referred to (rescreen-) 23 3 Participation Indicators (rescreen-) S S2 TTD S S2 TTD S S2 TTD Total number of individuals received rescreen- exam S S2 TTD S S2 TTD Mean/Average Age at Exam (Male) 2 Mean/Average Age at Exam (Female) Age Range (Male) Age Range (Female) of

5 5 6 Lab Studies/Findings (rescreen-) Line /IAPP- FWP Semi-Annual Report, S: October 2 - March Chest X-Rays (rescreen-) S S2 TTD S S2 TTD S S2 TTD 9 Total Number of Individuals Tested Number with Suspected Asbestosis without pleural disease Number with Suspected Asbestosis with pleural disease Number with Suspected Asbestos-related pleural 2 disease 3 Number with Suspected Silicosis Number with Suspected Mixed Dust 8 8 Pneumoconiosis Number with Suspected Pneumoconiosis, not otherwise specified Number with Suspicious Lung Nodules, Nodes, Lesions (suspicious for cancer) Pulmonary Function Tests (rescreen-) S S2 TTD S S2 TTD S S2 TTD 2 Total Number of Individuals Tested 2 Number with Restrictive Pattern 22 Number with Obstructive Pattern 23 Number with Mixed Pattern Beryllium Sensitization/Disease Testing 26 (rescreen-) S S2 TTD S S2 TTD S S2 TTD 27 Total Number of Individuals Tested 28 Number of Individuals with Abnormal BeLPT of

6 Line /IAPP- FWP Semi-Annual Report, S: October 2 - March Number of Individuals with 2 Abnormal BeLPTs Number of Individuals with Abnormal and Borderline BeLPTs Follow-up Recommended (rescreen-) S S2 TTD S S2 TTD S S2 TTD Potentially occupationally-related follow-up Non-occupationally-related follow-up RESCREEN-2 (3+ yrs since first rescreen) Outreach Information S S2 TTD Number of Potential Participants Attempted to Contact Directly (rescreen-2) 5 27 Indicators of Interest in Rescreen-2 S S2 TTD Total Number of Respondents Interested and Eligible (rescreen-2) 275 Number of Respondents Referred to (rescreen-2) 2 Participation Indicators (rescreen-2) S S2 TTD S S2 TTD S S2 TTD Total number of individuals received rescreen-2 5 exam of

7 Line /IAPP- FWP Semi-Annual Report, S: October 2 - March S S2 TTD S S2 TTD 5 Mean/Average Age at Exam (Male) 55 Mean/Average Age at Exam (Female) Age Range (Male) 57 Age Range (Female) Lab Studies/Findings (rescreen-2) Chest X-Rays (rescreen-2) S S2 TTD S S2 TTD S S2 TTD 62 Total Number of Individuals Tested Number with Suspected Asbestosis without pleural disease Number with Suspected Asbestosis with pleural 6 disease Number with Suspected Asbestos-related pleural disease 66 Number with Suspected Silicosis Number with Suspected Mixed Dust 67 Pneumoconiosis Number with Suspected Pneumoconiosis, not otherwise specified Number with Suspicious Lung Nodules, Nodes, Lesions (suspicious for cancer) Pulmonary Function Tests (rescreen-2) S S2 TTD S S2 TTD S S2 TTD 73 Total Number of Individuals Tested 7 Number with Restrictive Pattern 75 Number with Obstructive Pattern 76 Number with Mixed Pattern of

8 77 Line /IAPP- FWP Semi-Annual Report, S: October 2 - March Beryllium Sensitization/Disease Testing 79 (rescreen-2) S S2 TTD S S2 TTD S S2 TTD 8 Total Number of Individuals Tested 8 Number of Individuals with Abnormal BeLPT 82 Number of Individuals with 2 Abnormal BeLPTs Number of Individuals with Abnormal and Borderline BeLPTs Follow-up Recommended (rescreen-2) S S2 TTD S S2 TTD S S2 TTD Potentially occupationally-related follow-up Non-occupationally-related follow-up RESCREEN-3 (3+ yrs since second rescreen) Outreach Information S S2 TTD Number of Potential Participants Attempted to Contact Directly (rescreen-3) 3 2 Indicators of Interest in Rescreen-3 S S2 TTD Total Number of Respondents Interested and Eligible (rescreen-3) 5 25 Number of Respondents Referred to (rescreen-3) 8 of

9 Line /IAPP- FWP Semi-Annual Report, S: October 2 - March 22 Participation Indicators (rescreen-3) S S2 TTD S S2 TTD S S2 TTD Total number of individuals received rescreen-3 23 exam S S2 TTD S S2 TTD 27 Mean/Average Age at Exam (Male) 28 Mean/Average Age at Exam (Female) Age Range (Male) 2 Age Range (Female) 2 22 Lab Studies/Findings (rescreen-3) Chest X-Rays (rescreen-3) S S2 TTD S S2 TTD S S2 TTD 25 Total Number of Individuals Tested Number with Suspected Asbestosis without pleural disease Number with Suspected Asbestosis with pleural 27 disease Number with Suspected Asbestos-related pleural 28 disease 29 Number with Suspected Silicosis Number with Suspected Mixed Dust 22 Pneumoconiosis Number with Suspected Pneumoconiosis, not 22 otherwise specified Number with Suspicious Lung Nodules, Nodes, 222 Lesions (suspicious for cancer) of

10 Line /IAPP- FWP Semi-Annual Report, S: October 2 - March Beryllium Sensitization/Disease Testing 232 (rescreen-3) S S2 TTD S S2 TTD S S2 TTD 233 Total Number of Individuals Tested 23 Number of Individuals with Abnormal BeLPT 235 Number of Individuals with 2 Abnormal BeLPTs Number of Individuals with Abnormal and Borderline BeLPTs Pulmonary Function Tests (rescreen-3) S S2 TTD S S2 TTD S S2 TTD 226 Total Number of Individuals Tested 227 Number with Restrictive Pattern 228 Number with Obstructive Pattern 229 Number with Mixed Pattern Follow-up Recommended (rescreen-3) S S2 TTD S S2 TTD S S2 TTD Potentially occupationally-related follow-up Non-occupationally-related follow-up 2 2 TOTALS Site- Specific TTD TTD Total (Sitespecific & ) Initial screen,22 92,33 Rescreen Rescreen Rescreen Total exams 2,6 2,27 of

11 Line /IAPP- FWP Semi-Annual Report, S: October 2 - March 22 NOTES/COMMENTS/QUALIFIERS D32, D9, D5, D62, D63, D97, D9, D, D, D2, D, D2, D23, D27, D28, D29, D5, D62, D6, D65, D8, D8, D23, D22 Numbers may not add up to previous quarterly report due to ongoing data cleaning efforts and new definitions in data dictionary. C8: It is estimated that 7, people worked on Line /Division B at the IAAP. Line 2: Refers to new participants contacted by mail only. D2: Since 26, 3,837 Line former workers have received an initial recruitment mailing. Lines 3, 9,, 97: Refers to participants who responded by mail only. Participants were also contacted by phone and scheduled for a screening appointment. Lines 5-56, -6, 63-69, : 'S' is not updated due to delay in the two occ med doctors reading the CXR films. However, results will eventually be totaled in 'Total to Date.' Lines 6-63, 2-23, 7-76, : Numbers vary from previous reports due to new definition categories being added and new reporting criteria based on Hankinson LLN definitions. Lines 87,, 9: Refers to participants contacted about 3-year re-screening by mail only. of

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