1. Which of the following represents a correct ordering of the events that occur in the catabolism of glucose in the absence of O 2

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1 EXERCISE Which of the following represents a correct ordering of the events that occur in the catabolism of glucose in the absence of O 2 - (1) Glycolysis; TCA cycle; oxidative phosphorylation (2) Glycolysis; oxidative phosphorylation TCA cycle (3) Oxidative phosphorylation TCA cycle; glycolysis (4) Glycolysis; fermentation 2. Glycolytic pahtway from glucose to pyruvic acid involves 10 reactions. Each individual reaction needs - (1) One molecule of ATP (2) One molecule of ADP (3) One molecule of NAD (4) One molecule of specific enzyme 3. Glycolysis coocurs in the and produces which in the presence of O 2 enters the (1) Cytosol; pyruvate; mitochondrion (2) Cytosol; glucose; mitochondrion (3) Mitochondrion; pyruvate; chloroplast (4) Chloroplast; glucose cytosol 4. Which metabolic pathway is a common pathway to both anaerobic and aerobic metabolism - (1) TCA cycle (2) ETS (3) EMP pahtway (4) Kreb's cycle 5. ATP is - (1) An energy currency (2) an nucleotide (3) formed in both respiration and photosynthesis (4) All 6. The end product of glycolysis is - (1) pyruvate (2) The starting point of TCA cycle (3) The starting point for fermentation (4) All 7. 1st step (reaction) of glycolysis is - (1) Oxdative step (2) Reductive step (3) Endergonic (4) Exergonic 8. Glycolysis was discovered by - (1) Embden (2) Mayernof (3) Paranas (4) All 9. Glycolysis - (1) Takes place in living cells (2) Causes partial oxidation of glucose (one molecule) to form 2 molecules of pyruvic acid and 2 ATP as net gain (3) Uses 2 ATP at two steps (4) All 10. Respiration is - (1) Anabolic + Exergonic (2) Catabolic + Exergonic (3) Catabolic + Endergonic (4) Anabolic + Endergonic 11. Usable energy of respiration is - (1) used in charging biomolecules into activity (2) Stored as heat - Free NEET & IIT Study Meterial & Papers Page - 1

2 (3) Immediately consumed in cellular activities (4) Trapped in ATP molecules 12. Function of respiration is to - (1) make ATP (2) Make NADH (3) Get rid of glucose (4) Get rid CO In Respiration - (1) Dry wt decreases (2) C-C bonds of complex compounds break through oxidation in cells (3) Energy contained in the respiratory materials is released in a series of slow stepwise reactions controlled by enzymes (4) All 14. Which one performs both respiration and photosynthesis - (1) Root cells (2) Mesophyll (3) Ovum of angiosperm(4) Xylem parenchyma 15. For gaseous exhange plants have - (1) Stomata (2) Lenticels (3) Porin (4) 1 and The reasons why plants can get along without respiratory organs are - (1) Almost all living cells in a plant have their surfaces exposed to air (2) Plants have little demand for gas exchange (3) Taking care of its own gas exchange need by every part, little transport of gases, from one part to another (4) All 17. Why is different enzyme involved in each step of glycolysis - (1) Each step occurs in a different subcellular location (2) Each step occurs in a different cell (3) Each step involves different change in potential energy (4) Each step involves different chemical reaction 18. Nearly every living organism uses glucose as a nutrient source of energy. Why - (1) Glucose is the only molecule capable of provding the energy to produce ATP (2) The stucture of glucose is very similar to ATP (3) Glucose has more potential energy than any other respiratory substrate (4) The ability to harvest energy from glucose appeared very early in biological evolution 19. Glycolysis is - (1) Eukaryotic cells (2) Anaerobic cells (3) Virtually all cells (4) Virtually all cells 20. How many molecules of O 2 are used and how many CO 2 comes out during the glycolytic breakdown of one glucose molecules - (1) 1;2 (2) 2;1 (3) 0;0 (4) 36;6 - Free NEET & IIT Study Meterial & Papers Page - 2

3 21. 3PGAld is oxidised during glycolysis. What happens to the atoms and the e that are removed during during oxidation (1) They reduce NAD + (2) They oxidise NAD + (3) They are transferred to C 3 H 4 O 3 (Pyruvic acid) (4) They come out immediately in the form of H 2 O 22. Which one is false for glycolysis - (1) Substrate level phosphorylation occurs (2) The end products are CO 2 and H 2 O (3) ATP is formed (4) ATP is used 23. If glucose is labelled with 14 C, what molecule will become radioactive as glycolysis and TCA cycle are completed (1) Water (2) NADH (3) ATP (4) CO Glycolysis occurs in ; the TCA cycle occurs in ; and ETC occurs in (1) Mitochondrial matrix, cytosol; mitochondrial inner membrane (2) Cytosol, mitochondrial matrix; mitochondrial inner membrane (3) Mitochondrial outer membrane, cytosol; mitochondrial inner membrane (4) Cytosol, outer chamber of mitochondria; inner chamber of mitochondria 25. What will happen to glycolytic pathway if a cell runs completely out of ATP - (1) Glycolysis will speed to (2) Glycolysis will be slow down (3) Glycolysis will stop as first and third steps need ATP input (4) Glycolysis will increases as energy will be supplied by NADH During glycolysis, for each mole of glucose oxidised to pyruvate - (1) 6 moles of ATP are produced (2) 2 moles of NAD + are produced (3) 2 moles of ATP are used, and 4 mole of ATP are produced (4) No ATP is produced 27. During glycolysis, the conversion of one mole of 3PFAld to C 3 H 4 O 3 yield 2 moles of ATP. But the oxidation of glucose to C 3 H 4 O 3 produces a total of 4 moles of ATP. Where do the remaining 2 moles of ATP come from - (1) One mole of glucose gives 2 moles of 3PGAld (2) Glycolysis produces 2NADH (3) Fermentation of C 3 H 4 O 3 produces 2ATP more (4) 2ATP are used in the converstion of glucose to 3PGAld 28. For glycolysis to continue, all cells is require - (1) O 2 (2) Mitochondria (3) ETS (4) NAD The oxidation of pyruvic acid to CO 2 is called - (1) Fermentation (2) TCA/ Citric acid cycle (3) Glycolysis (4) Oxidative phosphorylation 30. During the enregy - priming portion of glycolysis, the phosphates from ATP molecules are - (1) Added to first and 6th carbon (2) Added to 1st 4th carbon (3) Wasted, as an energy investment (4) Used to make lactate - Free NEET & IIT Study Meterial & Papers Page - 3

4 31. In absence of O 2 cells capable of fermentation - (1) Accumulate glucose (2) No longer produce ATP (3) Accumulate pyruvate (4) Oxidise NADH to produce NAD For bacteria to continue growing rapidly when they are shifted from an environment containing O 2 to an anaerobic environment, they must - (1) Produce more ATP per mole of glucose during glycolysis (2) Produce ATP during oxidation of NADH (3) Increase the rate of glycolysis (4) Increase the tate of TCA cycle 33. In alcoholic fermentation, NAD + is produced during the - (1) Reduction of acetyldehyde to ethanol (2) Oxidation of glucose (3) Oxidiation of pyruvate to acetyl CoA (4) Hydrolysis of ATP to ADP 34. The free energy released during of 3PGAld to 1,3 di PGA is - (1) Used to oxidise NADH (2) Lost as heat (3) Used to form ATP (4) Used to reduce NAD The results of first five reactions of the glycolytic pathway are - (1) Adding phosphate, modifying sugars, and forming 3PGAld (2) Removal of e and H + from glucose (3) Oxidation of pyruvate and formation of acetyl CoA (4) Oxidation step 36. Fermentation always prodces - (1) AMP (2) NAD + (3) Pi (4) DNA 37. Choose the correct combination between respiratory substrates and their respective RQs. Carbohydrate Fat Protein (1) (2) (3) (4) Fermentation takes place - (1) Under anaerobic conditions in many prokaryotes and unicellular eukaryotes (2) Under aerobic conditions in many prokaryotes and unicellular eukaryotes (3) Under aerobic conditions in all prokaryotes and unicellular eukaryotes (4) Under aerobic conditions in all prokaryotes and unicellular eukaryotes 39. In order for glucose to used as an energy source, it is necessary that - (1) Glucose be formed from fructose (2) Glucose be degraded to CO 2 (3) 2 molecules of ATP be inversted in the system (4) None - Free NEET & IIT Study Meterial & Papers Page - 4

5 40. Many species derives their energy from fermentation. The function of fermentation is to - (1) Reduce ND + (2) Oxidise CO 2 (3) Oxidise NADH + H +, ensuring a continued supply of ATP (4) Production of acetyl CoA 41. Which of the following cellular metabolic processes can occur in the presence or absence of O 2 - (1) Glycolysis (2) Fermentation (3) TCA cycle (4) Electron transport coupled with chemiosmosis 42. The main purpose of cellular respiration is to - (1) Convert potential to kinetic energy (2) Convert kinetic to potential energy (3) Creat energy in the cell (4) Convert energy stored in the chemical bonds of glucose to an energy that the cell can use 43. If O 2 is not present, yeast cells break down glucose to - (1) CO 2 + H 2 O (2) CO 2 + Lactic acid (3) CO 2 + Pyruvic acid (4) C 2 H 5 OH and CO NAD + is - (1) a protein (2) an oxidising agent (3) a reducing agent (4) formed under only aerobic conditions 45. In term of efficiency at converting the energy of glucose in ATP - (1) aerobic glycolysis is better than TCA cycle (2) eukaryotic cells are more effcient than prokaryotic cells (3) Electron transport chain is not necessary for high efficiency (4) Anaerobic conditions are much less efficient than aerobic 46. Which of the following statements about cellular energy - harvesting pathway is false - (1) Autotrophs can produce their own food but must obtain energy from it by glycolysis and cellular respiration (2) Fermentation usually occurs under anaerobic conditions (3) Pyruvate oxidation can only occur under aerobic conditions (4) None 47. Which of the following statements regarding metabolic pathways is false - (1) Many of the steps of glycolysis can run in reverse (2) Starch, sucrose or glycogen must be hydrolysed before it can enter the glycolysis (3) After fats are digested glycerol enters glycolysis by forming DHAP (4) After fats digestion, fatty acids can no longer participate in cellular respiration - Free NEET & IIT Study Meterial & Papers Page - 5

6 48. Identify A, B and C - A B C (1) NAD + Ethanol Lactic acid (2) Ethanol NAD + Lactic acid (3) Lactic acid Ethanol NAD (4) NAD Lactic acid Ethanol 49. In animals cells, like muscle, during exercise, when O 2 is inadequate for cellular respiration, pyruvic acids is reduced into lactic acid by - (1) O 2 (2) Carboxylation (3) Lactate dehydrogenase (4) All 50. Pyruviate C 2 H 5 OH + CO 2 The above reaction needs 2 enzymes named as - (1) Pyruvate decarboxylase and alcohol dehydrogenase (2) Pyruvate decarboxylase and alcohol enolase (3) Pyruvate decarboxylase and pyruvate kinase (4) Pyruvate carboxylase + Aldolase 51. Which one is true - (1) In absence of O 2, fermentation regenerates teh NAD + needed for glycolysis (2) Fermentation does not liberate all the energy available in each sugar molecule (3) When alcohol conc. reaches 13%, the yeast cells become poisoned and die (4) All 52. Which one is false - (1) Less than 7% of energy in glucose is released during lactic or alcoholic fermentation (2) Fermentation is observed in all cells - Free NEET & IIT Study Meterial & Papers Page - 6

7 (3) O 2 is an essential requirement for aerobic respiration but enters the respiratory process at the end (4) In aerobic respiration glucose is broken down into CO 2 + H 2 O 53. Where is ATP synthesized in glycolysis - (1) When 1,3 di PGA is changed into 3 PGA (2) When PEPA is changed into pyruvic acid (3) When Fr. 1, 6 di P is borken in Triose phosphate (2 molecules) 54. (4) Both 1 and 2 Choose the correct names of A,B, C and D - A B C D (1) 1,3 di PGA 3 PGAld Fr. 1, 6 di P Fr. 6P (2) 3 PG Ald 1,3 di PGA Fr. 1,6 di P Fr. 6P (3) Fr. 1,6 di P Fr. 6P 3 PGAld 1,3 di PGA (4) Fr. 6P Fr. 1,6 di P 3 PGAld 1,3 di PGA 55. A the end of glycolysis X is the net energy gain from one molecule of glucose via Y, but there is also energy stored in the from of Z - X Y Z (1) 1 ATP Oxidative phosphorylation NADH + H + (2) 2 ATPs Oxidative phosphorylation NADH + H + (3) 2 ATPs Substrate phosphorylation NADPH + H + (4) 2ATPs Substrate level phosphorylation NADH + H + - Free NEET & IIT Study Meterial & Papers Page - 7

8 56. In Kreb's cycle, the first product is citric acid which is a 6-compoud. It is formed by a condensing irrversible reaction between - (1) OAA and Pyruvic acid (2) OAA and Acetyl Coenzyme A (3) Pyruvic and Acetyl Coenzyme A (4) OAA and Citrate synthetase 57. Conservsion of a-ketoglutaric acid into succinic acid is a step of - (1) EMP pathway (2) TCA cycle (3) HMP pathway (4) ED pathway 58. In Kreb's cycle, how many oxidation (dehydrogenation) occur - (1) 4 (2) 6 (3) 2 (4) Kreb's cycle was discovered by Krebs in pigeon muscles in Which step is called Gateway step/ Link reaction in aerobic respiration - (1) Glycolysis (2) Formation of acetyl / Coenzyme A (3) Citric acid formation (4) ETS terminal oxidation 60. In Kreb's cycle - (1) Acetyl coenzyme A undergoes 4 oxidation and 2 decarboxylation (2) Pyruvic aicd undergoes 4 oxidation and 2 decarboxylation (3) TCA undergoes 4 oxidation and 2 decarboxylation (4) OAA undergoes 4 oxidation and 2 decarboxylation 61. Fermentation is compelet breakdown of carbohydrate. It is perfromed by - (1) All microbes (2) Some fungi and some bacteria (3) All fungi and bacteria (4) Only yeast 62. At the end of the Kreb's cycle, most of energy removed from glucose molecule is transferred to - (1) NADH + H + / FADH + H + (2) ATP (3) OAA (4) Citric acid 63. Correct sequence of events in Kreb's cycle is - (1) Acetyl CoA Citrate Pyruvate -ketoglutarate Succinate Malate Fumarate OAA (2) Acetyl CoA Citric acid -kettoglutaric acid Succinate acid Malate Fumarate acid Malic acid OAA (3) Acetyl CoA Citric acid Malic acid -kettoglutaric acid Succinate OAA (4) All are wrong 64. Kreb's cycle is also called TCA (Tri Carboxylic acid Cycle) or citric acid cycle (Organic acid cycle). It is also called metabolic sink as it is - (1) Common pathway for carbohydrates, fats and proteins (amino acids) (2) Common pathway for carbohydrates, fats only (3) Common pathway for carbohydrates, and organic acids only (4) None of the above 65. Which is not found inside the mitochondrion - (1) Citric acid (2) PEP or PEPA (3) Malic acid (4) Ketoglutaric acid - Free NEET & IIT Study Meterial & Papers Page - 8

9 66. The first 5-C dicarboxylic acid in Kreb's cycle which is used in nitrogen metabolism is - (1) OAA (2) Citric acid (3) -ketoglutaric acid (4) Acetyl Coenzyme A 67. In Kreb's cycle, the H + removed at succinate level is accepted by - (1) FAD + (2) NAD + (3) ADP (4) FMN Kreb's cycle is completed with the formation of - (1) Citric acid (2) OAA (3) Succinic acid (4) Malic acid 69. Inside an active mitochondrion, most electrons follow which pathway - (1) Glycolysis NADH Oxidative Phosphorylation ATP O 2 (2) Kreb's cycle FADH 2 ETS ATP (3) ETS Kreb's cycle ATP O 2 (4) Kreb's cycle NADH + H + Electron transport chain O Most of the CO 2 is released during - (1) Glycolysis (2) The Kreb's Cycle (3) Lactate fermentation (4) Oxidative phosphorylation 71. In aerobic cellular respiration, which generates more ATP - (1) Substrate level phosphorylation (2) Chemiosmosis (3) Both generate the same amount of ATP(4) Neither generates ATP 72. Which one of the following statements correctly describes relationship between the Kreb's cycle and electron tranport 73. pathway - (1) The Kreb's cycle releases H + used by electron transport (2) The electron transport pathway obtains electron from the CO 2 produced by the Kreb's cycle (3) The Kreb's cycle and electron transport pathway, both produced ATP (4) NADH + H + produced by Kreb's cycle is used to make ATP by electron transport - Free NEET & IIT Study Meterial & Papers Page - 9

10 Identify X; Y; and Z - X Y Z 74. (1) GTP NADH 2 CO 2 (2) FADH 2 NADH 2 GTP (3) NADH 2 FADH 2 GTP (4) CO 2 NADH 2 ADP Identify by A and B - A (1) NADH + H + CO 2 (2) FAD + FADH + H + (3) CO 2 NADH + H + (4) CO 2 FADH + H + B 75. At the end of Krebs cycle, but before the electron transport chain, the oxidation of glucose has produced a net gain of (1) 3CO 2 5 NADH 2, 1 FADH 2, 2ATP (2) 6CO 2 10 NADH 2, 2 FADH 2, 4ATP (3) 6CO 2 10 NADH 2, 2 FADH 2, 38ATP (4) None of the above is correct 76. If oxygen is labelled with 18 O, which molecule will become radioactive as glycolysis, Kreb's cycle and oxidative phosphorylation are completed - (1) Water (2) CO 2 (3) ATP (4) NADH All of these events occur in the conversion of pyruvic acid into Acetyl CoA except - (1) Production of CO 2 (2) Conversion of 3-carbon molecule into a 2C molecule (3) Pyruvate dehydrogenase enzyme complex, several factors Mg 2+, NAD + and CoA are needed (4) Site of the reaction is cytosol - Free NEET & IIT Study Meterial & Papers Page - 10

11 78. How many carbon atoms are in S,T and U - S T U (1) (2) (3) (4) If 2 acetyl CoA molecules are fed into the Kreb's cycle, how many ATP molecules are synthesised directly in the cycle (1) 2 (2) 4 (3) 36 (4) Which one is correct - (1) Kreb's cycle and chemiosmosis are inhibited in anaerobic conditions (2) Both glucose and fructose radily enter the glycolytic pathway (3) Glucose and fructose are phosphorylated by Hexokinase (4) All 81. All of the following processes can release CO 2 except - (1) Alcohol fermentation (2) Oxidative decarboxylation and Kreb's cycle (3) Oxidative phosphorylation (4) -Ketogluatric acid succinic acid 82. Which of the following sequences correctly indicates the potential ATP yield of the indicated molecules from greatest ATP yield to least ATP yield - (1) Pyruvate, ethanol, glucose, acetyl CoA (2) Glucose, Pyruvate, acetyl CoA, NADH + H + (3) Glucose, FADH 2, Acetyl CoA, pyruvate (4) Glucose, FADH 2, NADH 2, pyruvate 83. The first reaction of Kreb's cycle i.e. condensation of acetyl group with OAA and water is catalysed by - (1) Citrate synthetase (2) Succinate dehydrogenase (3) RuBisCo (4) PEPCase - Free NEET & IIT Study Meterial & Papers Page - 11

12 84. Which of the following steps is associated with ATP formation (substrate level phosphorylation) - (1) Succinyl CoA Succinic acid (2) 1, 3 dipga 3 PGA (3) PEP Pyruvate (4) All 85. I. C 6 H 12 O 6 + NAD + + 2ADP + 2 ip 2C 3 H 4 O 3 + 2ATP + 2NADH + 2H + II. Pyruvic acid + 4NAD + + FAD + + 2H 12 O + ADP + Pi 3CO 2 + 4NADH + 4H + + ATP + FADH 2 III. Pyruvic C 2 H 5 OH + CO 2 Categorise the summary equations under respectively phases - I II III (1) Glycolysis Fermentation Kreb's cycle (2) Kreb's cycle Fermentation Glycolysis (3) Kreb's cycle Glycolysis Fermentation (4) Glycolysis Kreb's cycle Fermentation 86. Which one is correct - (1) During the fermentation,2 molecules of ATP per molecule of glucose is the net gain (2) Oxidative phosphorylation produces the most ATP in the cell (3) During TCA cycle oxidative steps are coupled to the reductions of e carries (4) All 87. In yeast cell, if TCA cycle is shut down due to lack of O 2, glycolysis will probably - (1) Shut down (2) Increase (3) Produce more ATP/ glucose molecule (4) Produce more NADH 2 / glucose molecule 88. O 2 is used by - (1) Citric acid cycle (2) Electron transport chain (3) Substrate level phosphorylation (4) ATP synthase 89. Water is the by product cellular respiration. The water is produced as a result of - (1) Conversion of pyruvate to acetyl CoA (2) Conversion of glucose to pyruvate (3) Combining carbon dioxide with protons (4) The reduction carbon dioxide with protons 90. The chemisoment generation of ATP is dirven by - (1) Osmotic movement from low OP to high OP (2) Oxidative phosphorlyation (3) A difference in H + concentration on both side of membrane (4) None 91. Most ATP in our bodies is made by - (1) Glycolysis (2) TCA cycle (3) Burning fat (4) ATP synthase - Free NEET & IIT Study Meterial & Papers Page - 12

13 92. The main purpose of electron transport chain is to - (1) Cycle NADH + H + back to NAD + (2) Use the intermediates from TCA cycle (3) breakdown pyruvate (4) All 93. Terminal e acceptor of e transport is - (1) CO 2 (2) C 6 H 12 O 6 (3) H 2 O (4) O Which statement concerning ATP synthesis is true - (1) ATP can be synthesised through substrate level phosphorylation, photophorylation and oxidative phosphorylation (2) The proton-motive force is establishment of proton gradients and electrochemical potentials across the inner membrane (3) Proton - motic force is essential for back of H + from outer chamber of matrix of mitochondria through proton channel (F 0 ) of F 0 -F 1 particle to produce ATP (4) 95. Choose the false statement - (1) Respiratory chain uses O 2 as final hydrogen aceptor (2) All living cells perform glycolysis (3) Glycolysis can operate in presence or absence of O 2 (4) CN cannot stop chemiosmosis 96. Go through the following statements about the chemiosmotic mechanism - I. Protons are pumped across the membrane II. Protons return through the membrane by way of channel protein III. ATP is required for protons to return IV. The membrane in question is the inner mitochondrial membrane V. Proton pumping is associated with the respiratory chain (1) V is inocorrect (2) III is inocrrect (3) All are incorrect except III (4) Only III is correct 97. Which of the following is not true of oxidative phosphorylation - (1) It uses oxygen as the intial e donor (2) It involves the redox reactions of electron transport chain (3) It involves an ATP synthase located in the inner mitochondrial membrane (4) It depends on chemiosmosis 98. The e carrier molecules and cytochrome - (1) Are reduced as they electrons on the next molecules (2) Transfer electrons between the electron carrier complexs (3) Shuttle protons to ATP synthase (4) Are found in outer mitochondrial membrane - Free NEET & IIT Study Meterial & Papers Page - 13

14 99. Choose the false option - (1) Flow of electrons in ETS is Fe +3 Fe +2 Fe +3 (2) In ETS electrons move from high negative to high positive redox potential (3) Cyta 3 has Fe and Cu (4) Cytochrome are non -proteinaceous but ubiquinone is proteinaceous 100. The oxidation of molecule of FADH 2 yield less ATP (2ATP) and a molecule of NADH 2 yields 3ATP but FADH 2 yields only 2 ATP because - (1) Carries few electrons (2) Passes its electrons to a transport molecule later in the chain and at a lower level (3) Has a lower in energy conformation than NADH 2 (4) Is formed in the cytosol and energy is lost when it shuttles its electron across the mitochondrial membrane 101. Which of the following conversions represents a reduction reaction - (1) Pyruvate Acetyl CoA (2) NADH + H + NAD + + 2H (3) 3 PGAld Pyruvate (4) Acetyldehyde Ethanol 102. I. Proton channel of oxysom/ complex V/ ATP synthase is located in F 0 II. Metabolic water is produced in terminal oxidation/ produced in respiration III. CoQ accept electron from NADH dehydrogenase (complex I) and also can accept electron from FADH 2 / succinate Q-reductase / complex II IV. Cytochrome c is a small protein attached to outer surface of the inner mitochondrial membrane and acts as a mobile carrier for transfer of electrons between complex II (Cyt bc, complex) and IV V. Complex IV refers to cytochrome c oxidase (cyta a, a 3 and 2 Cu per centre) VI. If a cell is treated with a drug that inhibits ATP synthase, the ph of mitochondrial matrix will increase (1) All are correct (2) All are correct (3) I and V are correct (4) Only II is correct 103. Which statement about oxidative phosphorylation is not true - (1) The inner mitochondrial membrane has 5 distinct respiratory or enzyme complexs (2) CoQ links complex I and II, and cyt c link complex III with complex IV (3) FAD, FMN, FeS clusters and copper are other cofactors that participtate in electron transfer (4) 38 ATPs are formed when one pair of protons return to matrix via F 0 of ATP synthase 104. The initial step in the biosynthesis of ATP by chemiosmosis in the mitochondrion is the - (1) Pumping of protons in the outer chamber (2) Pumping of electrons in the matrix (3) Action of ATP synthase (4) Formation of metabolic water 105. Which of the following shows correct order of electrons in mitochondria - (1) FeS NADH CoQ Cyt b FeS Cyc 1 Cyt c Cyt a 3 O 2 Cyt b (2) NADH FMN FeS CoQ Cyt b FeS Cytc 1 Cyt a Cyt a 3 O 2 (3) NADH Cyt c 1 Cyt c Cyt a Cyt a 3 O 2 FMN FeS CoQ Cyt b FeS - Free NEET & IIT Study Meterial & Papers Page - 14

15 (4) Cyt c 1 Cyt a Cyt a 3 NADH FMN FeS CoQ Cyt b FeS O Which of the following diagram represents of ATP synthesis in mitochondria through chemiosmosis I. M = Inner membrane M = Matrix O. C = Outer Chamber (1) (2) (3) (4) 107. Net gain of ATP molecules during aerobic respiration of one molecule of glucose is - (1) 36 (2) 40 (3) 39 (4) Select the wrong option - I. Fermentation is partial breakdown of glucose but aerobic respiration is the complete breakdown of glucose in CO 2 + H 2 O II. NADH + H + III. NADH + H + Very slow Fermentation Very slow NAD + Aerobic respiration NAD+ IV. In respiratory pathway glycerol changes into DHAP (1) None (2) All (3) I (4) III and IV 109. Out of 3 respiratory substrate (carbohydrates, fat and protein), which one is the most favoured substrate - (1) Glucose (2) Protein/ amino acid (3) Fat/ fatty acid (4) All 110. Respiratory pathway is - (1) Catabolic (2) Amphibolic (3) Anabolic (4) Non enzymatically controlled process 111. Which of the following is amphibolic - (1) Glycolysis (2) Oxidative decarboxylation of pyruvate (3) TCA cycle (4) Oxidative phosphorylation - Free NEET & IIT Study Meterial & Papers Page - 15

16 112. Kreb's Cycle is considered as amphibolic because of facts as follows - (1) The intermediates of the cycle are used as precursors in the biosnthesis of many compounds (2) It is sole process to produce ATP (3) It is the oxidation of acetyl CoA in CO and H 2 O (4) 1 and Choose the correct option Volume of CO 2 evolved (1) RQ = Volume of O consumed 2 (2) RQ depends on the types of respiratory material (3) Living organisms use respiratory substance (often more than one); pure lipid or fats are never used (4) All The above figure indicates the interrelationship among metabolic pathways. Now identify A to D - A B C D (1) Protein Acetyl CoA Fat DHAP (2) Fat DHAP Protein Acetyl CoA (3) Acetyl CoA Fat DHAP Protein (4) Fat DHAP Acetyl CoA Protein - Free NEET & IIT Study Meterial & Papers Page - 16

17 (C 51 H 98 O 6 ) + 145O 2 102CO H 2 O + Energy The RQ of above reaction is - (1) 1 (2) 0.7 (3) 1.45 (4) The adjoining diagram refers to mitochondrial electron transport chain. Identify the P, Q, R, S, T (1) P - matrix, Q - outer membrane, R - FMNH 2, S - NADH 2, T - 2H (2) P - outer chamber, Q - matrix, R - NADH + H +, S - NAD +, T - 2H + (3) P - outer membrane, Q - cristae, R - NAD +, S - NADH + H +, T - H 2 (4) P - cristae, Q - outer chamber, R - NADH + H +, S - NAD +, T - 2H Experiments 1, 2 and 3 were conducted synthetic vesicles containing F 0 - F 1 ATP synthase were prepared and incubated overnight a tube. Subsequently, the vesicles were transferred to another tube which has contained ADP and Pi (inorganic phosphate) (a) A proton gradient across the vesicular membrane will be present in both experiments 1 and 2 at the time of transfer. (b) As a consequence of the proton gradient, ATP will be synthesised in both experiments 1 and 2 (c) ATP will be synthesised in experiment 3 because Fo-F1 ATP synthase has the inherent property to catalyse the - Free NEET & IIT Study Meterial & Papers Page - 17

18 synthesis of ATP from ADP and Pi. (d) ATP will be synthesised in experiment 2 because the proton has to flow out of the vesicles through the F 0 - F 1 ATP synthase for ATP synthesis. (1) a and b (2) b and c (3) c and d (4) a and d 118. Six tubes containing preparations from animal tissue were set up as shown in the table Tube contents 1. glucose + homogenised cells 2. glucose + mitochondria 3. glucose + cytoplasm lacking organelles 4. pyruvic acid + homogenised cells 5. pyruvic acid + mitochondria 6. pyruvic acid + cytoplasm lacking organelles After incubation, in which three tubes would carbon dioxide be produced (1) 1, 2, 3 (2) 1, 4, 5 (3) 3, 4, 6 (4) 3, 5, In mitochondria, protons accumulate in the (1) outer membrane (2) inner membrane (3) intermembrane space(4) matirx 120. Anaerobic respiration produces... i... amount of energy as compqred to aerobic respiration because... ii... produced during anaerobic respiration is not broken down completely into CO 2 and H 2 O (1) i = lesser, ii = lactic acid (2) i = lesser, ii = citric acid (3) i = larger, ii = lactic acid (4) i = larger, ii = citric acid 121. Gylcolysis term has originated from Greek words (1) glycose and lysis (2) glyco and lysis (3) glyco and lysis (4) glucose and lysis 122. The ultimate electron acceptor of respiration in an aerobic organisms is (1) cytochrome (2) oxygen (3) hydrogen (4) glucose 123. Phosphorylation of glucose during glycolysis is catalysed by (1) Phosphoglucomutase (2) phosphoglucoisomerase (3) hexokinase (4) Phosphorylase 124. Pyruvic acid, the key product of glycolysis can have metabolic fates. Under aerobic condition it forms (1) Lactic acid (2) CO 2 + H 2 O (3) Acetyl CoA + CO 2 (4) Ethanol + CO The chemical substances involving in respiration eneter the mitochondrion from cytoplasm are (1) C 3 H 4 O 3, O 2, reduced NAD, ADP & Phosphate (2) C 6 H 12 O 6, reduced NAD, ADP & Phosphate (3) CO 2, NAD, ATP & water (4) Acetyl CoA, NADH 2, ADP & Phosphate 126. Which of the following exhibits the rate of respiration - (1) Growing shoot apex (2) Germinating seed (3) Root tip (4) Leaf bud - Free NEET & IIT Study Meterial & Papers Page - 18

19 127. Choose the correct statement - (1) Pyruvate is formed in the mitochondrial matrix (2) During the conversion of succinyl Co-A to succinic acid a molecule of ATP is synthesized (3) Oxygen in vital in respiration for removal of hydrogen (4) There is complete breakdown of glucose in fermentation 128. Mitochondria are called powerhouses of the cell. Which of the following observations support this statement - (1) Mitochondria synthesise ATP (2) Mitochondira have a double membrane (3) The enzymes of the Krebs cycle and the cytochromes are found in mitochondria (4) Mitochondria are found in almost all plants and animal cell 129. The end product of oxidative phosphorylation is - (1) NADH (2) Oxygen (3) ADP (4) ATP + H 2 O 130. Match the following and choose the correct option from those given below - Column -A Column - B A. Molecular oxygen (i) -Ketoglutaric acid B. Electron acceptor (ii) hydrogen acceptor C. Pyruvate dehydrogenase (iii) cytochore C D. Decarboxylation (iv) acetyl CoA Options - (1) A-(ii), B- (iii), C (iv), D - (i) (2) A-(iii), B- (i), C (iii), D - (iv) (3) A-(ii), B- (i), C (iii), D - (iv) (4) A-(iv), B- (iii), C (i), D - (ii) 131. The three boxes in this diagram represent the three major biosynthetic pathways in aerobic respiration. Arrows represent net reactants product - Arrows numbered 4,8 and 12 can all be - (1) NADH (2) ATP (3) H 2 O (4) FAD + or FADH Which of the metabolites is common to respiration mediated breakdown of fats, carbohydrates adn proteins - (1) Glucose -6-phosphate (2) Fructose 1,6-bisphosphate (3) Pyruvic acid (4) Acetyl CoA - Free NEET & IIT Study Meterial & Papers Page - 19

20 133. Substrate level phosphorylation accounts for approximately what percentage of the ATP formed by the reactions of glycolysis - (1) 0% (2) 2% (3) 10% (4) 100% 134. What is the purpose in having several steps in glycolysis or the Krebs cycle rather than a single step from glucose and oxygen to carbon dioxide and water - (1) The multistep approach increases the amount of heat produced in the reaction (2) The multistep approach increases the amount of potential produced in the reaction (3) The multistep approach is the only way to convert glucose to carbon dioxide (4) The multistep approach makes better use of the potential energy in the reaction 135. Why does NADH donate electrons to the beginning of the electron transport chain, whereas FADH 2 donates electrons to the middle of the chain - (1) FADH 2 is more rapidly oxidized than NADH (2) NADH has more electrons to donate than FADH 2 (3) FADH 2 has more reducing potential than NADH (4) NADH has more potential energy than FADH When do cells switch from cellular respiration to fermentation - (1) when electron acceptors are not available (2) when NADH and FADH 2 supplies are low (3) when the proton- motive force runs down (4) when pyruvate is not available 137. In which one of the following processes CO 2 in not released - (1) Aerobic respiration in plants (2) Aerobic respiration in animals (3) Alcoholic fermentation (4) Lactate fermentation 138. Match the organic compounds listed under Column -I with the explanation given under Column-II. Choose the appropriate option from the given choices Column - I Column II A. phosphoenol pyruvate (PEP) p. 6- carbon compound B. Ribulose biphosphate (RuBP) q. 2- carbon compound C. Oxaloacetic acid (OAA) r. 4- carbon compound D. Acetyl co-enzyme-a s. 5- carbon compound t. 2- carbon compound (1) A-t, B-s, C-r, D-q (2) A-s, B-t, C-r, D-q (3) A-t, B-p, C-q, D-r (4) A-q, B-r, C-s, D-t - Free NEET & IIT Study Meterial & Papers Page - 20

21 139. How many ATP are produced when one molecule of FADH 2 is oxidized to FAD throgh Electron Transport System - (1) 2 (2) 3 (3) 1 (4) Out of 38 molecules of ATP produced upon aerobic of glucose, the break up in ATP prodduction in glycolysis (P) pyruvate fo acetyl -CoA formation (Q) and Krebs cycle (R) is as follows - (1) P = 2, Q = 6, R = 30 (2) P = 8, Q = 10, R = 24 (3) P = 8, Q = 10, R = 20 (4) P = 2, Q = 12, R = Inner membrane of mitochondria is permeable to - (1) glucose (2) fructose (3) sucrose (4) ATP Answer key Q A Q A Q A Q A Q A Q A Q A Q. 141 A. 4 - Free NEET & IIT Study Meterial & Papers Page - 21

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