Cholestin. Cholesterol Health Paras Kolesterol Yang Sihat. English / Bahasa Melayu
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1 Cholestin Cholesterol Health Paras Kolesterol Yang Sihat English / Bahasa Melayu
2 The OVERVIEW of Red Yeast Rice PENGAMBARAN KESELURUHAN Beras Yis Merah The proprietary ingredient in Cholestin is red yeast fermented from premium rice (in Chinese, Hung-chu or Hong Qu ). Red yeast rice is traditionally prepared by the fermentation of washed non-glutinous rice using red wine mash, natural juice of Polygonum and alum water. This yeast has been used for centuries in China to produce rice wine, as a food preservative for maintaining the colour and taste of fish and meat and for its medical properties. The ancient Chinese pharmacopoeia Ben Cao Gang Mu records the use of this yeast to maintain health. Ramuan proprietari dalam Cholestin merupakan beras berkualiti tinggi yang telah ditapai dengan yis merah (juga dikenali sebagai Hung-chu atau Hong Qu dalam bahasa Cina). Secara tradisi, beras yis merah biasanya disediakan melalui penapaian beras yang telah dicuci dan dimasak dalam campuran wain merah, jus semulajadi Polygonum dan air alum. Di Negara China, yis ini telah digunakan semenjak zaman dahulu untuk membuat wain beras, sebagai pengawet makanan untuk mengekalkan rasa dan warna ikan dan daging, serta untuk kegunaan perubatan. Farmakopeia Cina purba yang berjudul Ben Cao Gang Mu menyatakan bahawa yis ini boleh mengekalkan kesihatan umum. What is Cholestin? Apakah Cholestin? Cholestin is a proprietary scientifically standardized and all natural form of Monascus Purpureus Went yeast fermented from premium rice. Every capsule of Cholestin contains 600mg of high quality Red Yeast Rice (Monascus Purpureus Went). Cholestin mengandungi tapaian beras yang berkualiti tinggi dengan yis Monascus Purpureus Went semulajadi dengan cara propietari mengikut piawaian secara saintifik. Setiap kapsul mengandungi 600mg yis merah. 2
3 Benefits of Cholestin FAEDAH-FAEDAH CHOLESTIN Promotes healthy cholesterol level* Maintains Blood Lipid Levels Promotes cardiovascular health Citrinin-free 100% natural, proprietary ingredient Menggalakkan paras kolesterol yang sihat* Mengekalkan Paras Lipid Darah Menggalakkan kesihatan kardiovaskular Bebas daripada citrinin 100% ramuan semulajadi proprietari * These benefits were established in clinical studies for subjects with total serum cholesterol less than 230mg/dl and triglyceride. * Manfaat ini telah ditubuhkan dalam kajian klinikal bagi subjek dengan jumlah kolesterol serum kurang daripada 230mg/dl dan trigliserida. types of Cholesterol jenis-jenis Kolesterol Low-density lipoprotein (or LDL) cholesterol is the bad cholesterol that clogs blood vessels, increasing the risk of heart disease. High-density lipoprotein (or HDL) cholesterol is the good cholesterol that transports LDL cholesterol from the tissues to the liver to be broken down, preventing the clogging for the blood vessels. Triglyceride consists of three ( tri- ) fatty acid molecules and an alcohol glycerol ( glyceride ) molecule that serves as the backbone for many types of lipids (fats). Kepadatan rendah lipoprotein (atau LDL) kolesterol adalah kolesterol tidak baik yang menyekat saluran darah, meningkatkan risiko penyakit jantung. Kepadatan tinggi lipoprotein (atau HDL) kolesterol adalah kolesterol baik yang mengangkut LDL kolestrol dari tisu badan kita ke hati untuk dipecahkan dan mencegahkan saluran darah dari tersumbat. Trigliserida terdiri daripada tiga ( tiga ) molekul asid lemak digabungkan dengan molekul gliserol alkohol ( glyceride ) yang berfungsi sebagai tulang belakang kepada pelbagai jenis lipid (lemak). 3
4 WHY CHOLESTEROL LEVEL INCREASES? MENGAPAKAH TAHAP KOLESTEROL MENINGKAT? Intake of fatty food or food with high oil content Obesity Lack of exercise Genetic Aging Gender. Women before menopause have lower cholesterol level than men of the same age; cholesterol level in women will increase after menopause. Pengambilan makanan berlemak atau makanan yang mengandungi minyak yang tinggi Obesiti Kurang bersenam Genetik Penuaan Jantina. Wanita sebelum menopaus mempunyai paras kolesterol yang lebih rendah berbanding dengan lelaki umur yang sama, paras kolesterol dalam wanita akan meningkat selepas menopaus. How does Cholestin work? Bagaimanakah Cholestin berfungsi? 80% of the cholesterol in the body is produced by the liver. The remaining portion of cholesterol comes from dietary consumption of foods containing cholesterol. The naturally occurring HMG-CoA reductase inhibitors in Cholestin work in the body by lowering the body s cholesterol production. 80% daripada kolesterol dalam badan dihasilkan oleh hati. Bahagian baki kolesterol berasal dari pengambilan makanan yang mengandungi kolesterol. HMG-CoA reductase inhibitor yang semulajadi dalam Cholestin berfungsi di dalam badan kita dengan mengurangkan penghasilan kolesterol daripada badan sendiri. 4
5 Competitive AdvantageS KEUNGUGGULAN KOMPETITIF 1. Cholestin contains standardized component of red yeast rice. 2. Supported by clinical trials that the intake of the proprietary ingredient in Cholestin as a food supplement promotes general wellness. 3. Cholestin contains 0.4% (9.6mg) HMG CoA reductase inhibitor per daily recommended dosage. 4. Global Recognitions Won Taiwan National Biotechnology & Medical Care Quality Award 2001 Received Healthy Food License (A0004) from Taiwan Department of Health 1. Cholestin mengandungi beras yis merah yang dihasilkan secara piawaian. 2. Disokongi oleh ujian klinikal dimana pengambilan ramuan propietari dalam Cholestin sebagai pengambilan suplemen dapat mengekalkan kesihatan umum. 3. Cholestin mengandungi 0.4% (9.6mg) HMG-CoA reductase inhibitor dalam dos harian. 4. Pengiktirafan Anugerah Global Mendapat Anugerah Biotechnologi & Kualiti Penjagaan Perubatan Kebangsaan Taiwan 2001 Menerima Lesen Makanan Kesihatan (A0004) daripada Jabatan Kesihatan Taiwan pada tahun S QUALITY PROCESS PROCESS KUALITI 6S Cholestin is manufactured under the Pharmanex 6S quality process. Pharmanex analyzes the final product to ensure that it is citrinin-free. Citrinin (fermentation by-product) is a mycotoxin produced by some yeast and molds. Cholestin dihasilkan di bawah proses kualiti Pharmanex 6S. Pharmanex menganalisiskan hasil akhir ramuan untuk memastikan ia bebas daripada citrinin. Citrinin (hasil sampingan dalam proses penapaian) merupakan sejenis mycotoxin yang dihasilkan oleh yis dan kulat. 5
6 SCIENTIFIC SUPPORT SOKONGAN SAINTIFIK Maintaining Healthy Cholesterol Level Menggalakan Paras Kolesterol yang Sihat Large multi-center study conducted at 11 U.S clinical centre sites by both primary care physicians and cardiologists have proven that Cholestin, together with low fat diet and moderate exercise, can help maintain healthy cholesterol level. No of subjects: 187 (116 men and 71 women) with total cholesterol (TC, ± 1.3 mg/dl), LDL-cholesterol (LDL-c, ±1.1 mg/dl), triglycerides (TG, ± 5.5 mg/dl) Clinical Findings: Large multi-centre study conducted at 11 U.S clinical centre sites showed that Cholestin : Reduced TC (16 ± 0.7%.) Reduced LDL-c (22 ± 1.2%) Reduced TG (4.0 ± 2.9%) Conclusion: Cholestin promotes healthy cholesterol level (TC, LDL-c and TG) Kajian yang dijalankan di 11 pusat klinikal di Amerika Syarikat oleh doktor penjagaan asas dan pakar kardiologi telah membuktikan Cholestin, bersama dengan diet rendah lemak dan senaman yang sederhana, boleh membantu mengekalkan paras kolesterol yang sihat. Nombor subjek: 187 (116 lelaki dan 71 wanita) dengan jumlah kolesterol (TC, ± 1.3 mg / dl), LDL-kolesterol (LDL-c, ± 1.1 mg / dl), trigliserida (TG, 166,8 ± 5.5 mg / dl) Penemuan klinikal: Kajian yang dijalankan di 11 pusat klinikal pihak Amerika Syarikat menunjukkan bahawa Cholestin : Mengurangkan TC (16 ± 0.7%.) Mengurangkan LDL-c (22 ± 1.2%) Mengurangkan TG (4.0 ± 2.9%) Kesimpulan: Cholestin menggalakkan paras kolesterol yang sihat (TC, LDL-c dan TG) Source Sumber: Rippe J, Bonovich K, Colfer H, et al. A multi-center, self-controlled study of Cholestin in subjects with elevated cholesterol. Circulation. 1999;99:
7 FREQUENTLY ASKED QUESTIONS SOALAN- SOALAN LAZIM Q1. A1. Can I take Cholestin if I am currently on medication? Bolehkah saya mengambil Cholestin sekiranya saya sedang mengambil ubat preskripsi? It is impossible for us to know all the interactions that can occur when taking Pharmanex products along with drugs. If you are currently on a prescription medication (or with a medical condition), we recommend that you consult your doctor prior to taking any Pharmanex products. Pharmanex tidak mungkin dapat mengetahui semua kesan sampingan yang boleh berlaku apabila produk Pharmanex diambil bersama ubat lain. Sekiranya anda sedang mengambil ubat preskripsi (atau mempunyai masalah kesihatan), kami mencadangkan supaya anda mendapat nasihat daripada doktor sebelum mengambil produk Pharmanex. Q2. A2. How long must an individual take Cholestin before realizing its benefits? Berapa lamakah seseorang individu perlu mengambil Cholestin sebelum menyedari manfaat dalam menurunkan kolesterol? Based on the findings from a study done by Rippe et.al (1999)*, an individual may experience reduced cholesterol levels after four (4) weeks while optimum results will be observed after eight (8) weeks with Cholestin. Berdasarkan penemuan daripada kajian yang dijalankan oleh Rippe et.al (1999), seseorang individu dapat menyedari paras kolestrol kurang dalam tempoh empat (4) minggu, manakala hasil yang optimum dapat diperhatikan selepas lapan (8) minggu dengan pengambilan Cholestin. * Experiment based on total cholesterol between 200 and 240mg/dL * Eksperimen adalah berdasarkan jumlah kolestrol di antara 200 dan 240mg/dL 7
8 Product Suitability Kesesuaian Produk Recommended Dosage Cadangan Pengambilan Contents Kandungan Cholestin is recommended for healthy adults concerned about maintaining desirable cholesterol levels. Cholestin dicadangkan untuk orang dewasa yang ingin mengekalkan paras kolesterol yang sihat. Take two (2) capsules twice daily with your morning and evening meals. Cholestin must be taken regularly. Do not take more than four (4) capsules within 24 hours. Discontinue if you experience any unexplained muscle pain or tenderness, especially if accompanied by flu-like symptoms. Ambil dua (2) kapsul dua kali sehari dengan sarapan pagi dan makan malam anda. Cholestin mesti diambil secara tetap. Jangan ambil lebih daripada empat (4) kapsul dalam lingkungan masa 24 jam. Sila hentikan pengambilan produk ini jika anda mengalami sebarang kesakitan otot atau ketenderan, terutamanya apabila gejala selsema berlaku. 120 capsules/bottle 120 kapsul/botol To know more about Nu Skin products, please contact our authorized distributors. Sila hubungi pengedar-pengedar berdaftar untuk mengetahui produk Nu Skin dengan lebih lanjut. Nu Skin (Malaysia) Sdn Bhd ( V) License No. AJL Lot 01-05, Level 1, PNB Darby Park Retail, No. 10, Jalan Binjai, Kuala Lumpur Tel: Fax: NuSkin Pharmanex (B) Sdn Bhd D2, Blk D, Lot 11620, Jalan Gadong Bandar Seri Begawan BE1718 Brunei Darussalam Tel: Fax: /14
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