Non-hematogenous endogenous pigments
|
|
- Rosalind Henry
- 6 years ago
- Views:
Transcription
1
2 Non-hematogenous endogenous pigments 0 This group contains the following : 1. Melanins. 2. Lipofuscins. 3. Chromaffin. 4. Pseudomelanosis. 5. Dubin-Johnson pigments. 6. Ceroid-type lipofuscins. 7. Hamazaki-Weisenberg bodies.
3 1. Melanins 0 Melanins are a group of pigments whose colour varies from light brown to black. 0 They are normally found in the skin, eye, substania nigra of the brain and hair follicles. 0 Under pathological conditions it is found in benign nevus cell tumours and malignant melanomas. 0 The melanins are bond to proteins, and these complexes are localized in the cytoplasm of cells within melanin granules.
4 0 Melanins are produced from tyrosine by the action of an enzyme tyrosinase, this enzyme act upon the tyrosine to produce the substance kown as dihydroxyphenylalanine (DOPA), which is subsequently rapidly acted upon by the same enzyme to produce an intrmedate pigment which then polymerizes to produce melanin.
5 Methods of demonstration 0 A number of methods can be used : 1. Reducing methods such as Masson-Fontana silver technique and Schmorl's ferric-ferricyanide reduction test. 2. Enzyme methods e.g. DOPA reaction. 3. Solubility and bleaching characteristics. 4. Fluorescent methods. 5. Immunocytochemistry.
6 Reducing methods 0 Melanin is a powerful reducing agent so its able to reduce ammonical silver solution to form metallic silver (Masson's method). 0 Melanin will reduce ferricyanide to ferrocyanide with the production of Prussian blue in the prescence of ferric salts (Schmorl's method). This type of reactio is also seen in other pigments such as lipofuscins, bile and neuroendocrine cell granules.
7 Enzyme methods 0 Cells that are capable of producing melinin can be demonstrated by the DOPA. The enzyme tyrosinase that is localized within these cells will oxidase DOPA to form an insoluble brown black pigments. 0 The best results are obtained when using post fixed cryostat sections.
8 2. Lipofuscins 0 These yellow brown to redish brown pigments occur widely throughout the body and are thought to be produced by an oxidation process of lipids and lipoproteins. 0 The oxidation process occurs slowly and progressively, and therefore the pigments exhibit variable staining reactions, different colours and variation in shape and size. 0 Lipofuscins can be found in the following sites:
9 0 Hepatocytes. 0 Cardiac muscles particularly around the nucleus. 0 Inner reticular layer of the normal adrenal cortex. 0 Testis. 0 Ovary. 0 Cytoplasmic inclusions in the neurons of the brain. 0 Some lipid storage disorders e.g. Batten's disease. 0 Other tissues such as bone marrow, involuntary muscles, cervix and kidney.
10 Methods of demonstration 0 The lipofuscins react with a variety of histochemical methods such as: 0 Periodic acid-schiff's method. 0 Schmorl's ferric-ferricynade reduction test. 0 Long Ziehl-Neelson method. 0 Sudan black B method. 0 Gomori's aldehyde fuchsin technique. 0 Masson-Fontana silver method. 0 Basophilia using methyl green.
11 3. Chromaffin 0 This pigments is normally found in the cells of the adrenal medulla as a dark brown materials. 0 It may occur in the tumours of the adrenal medulla (pheochromocytomas). 0 Fixation in formalin, alcohol is not recommended, dichromate containing fixatives is recommended. 0 Chromaffin can be demonstrated by Lillie's Nile blue A, Schmorl's reaction, PAS technique.
12 4. Pseudomelanosis 0 This pigments can be found in macrophages in the lamina propria of the large intestine and appendix. 0
13 5. Dubin-Johnson pigments 0 This pigments is found in the liver of patients with Dobin-Johnson syndrome and is due to defective canalicular transport of bilirubin. 0 Its brownish black granular intracellular pigments situated in the centrilobular hepatocytes. 0 Its simmilar to the lipofuscin, but ultra structurally are differ.
14 6. Hamazaki-Weisenberg bodies 0 These small yellow-brown spindle-shaped structures are found mainly in the sinuses of lymph nodes, either lying free or as cytoplasmic inclusions. 0 They associated with sacoidosis, melanosis coli. 0 Histochemically they are similar to lipofuscin, and at ultra structural level have an appearance that suggests that they are probably giant lysosomal residual bodies.
15 0 The end
Pathological Pigmentation
Pathological Pigmentation By Dr. Hemn Hassan Othman PhD, Pathology, Fall 2018 10/20/2018 1 Pathological Pigmentation: Pigments: Pigments are colored substances accumulate abnormally within the tissue and
More informationHemosiderin. Livia Vida 2018
Hemosiderin Livia Vida 2018 Questions Histochemical caracteristics of the different pigments. Exogenous pigments. Hemoglobinogenic pigments. Causes and forms of jaundice. Hemoglobinogenic pigments. Pathological
More informationLysosomes. Gr: lysis solution, soma body. Membrane bounded vesicles. Usually round ovoid or irregular electron dense bodies m.
Lysosomes Gr: lysis solution, soma body Membrane bounded vesicles Usually round ovoid or irregular electron dense bodies 0.05 0.5 m. Lysosomes No. varies from a few to several hundred per cell, in different
More informationCONVERSION OF AMINO ACIDS TO SPECIALIZED PRODUCTS DR. A. TARAB DEPT. OF BIOCHEMISTRY HKMU
CONVERSION OF AMINO ACIDS TO SPECIALIZED PRODUCTS DR. A. TARAB DEPT. OF BIOCHEMISTRY HKMU In addition to serving as building blocks for proteins, amino acids are precursors of many nitrogen-containing
More informationFixation... Questions 1 Answers 16. Processing... Questions 25 Answers 36. Safety... Questions 67 Answers 73
Table of Contents Fixation... Questions 1 Answers 16 Processing... Questions 25 Answers 36 Instrumentation... Questions 43 Answers 58 Safety... Questions 67 Answers 73 Laboratory Mathematics & Solution
More informationSpecial Staining (I)
Special Staining (I) Carbohydrates 1- PERIODIC ACID SCHIFF'S (PAS ) Purpose: Glycogen is present in liver, kidney, skeletal and cardiac muscle. The PAS stain is used to demonstrate neutral polysaccharides
More informationMucoprotein-containing histiocytes (muciphages)
J. clin. Path. (1966), 19, 368 Mucoprotein-containing histiocytes (muciphages) in the rectum J. G. AZZOPARDI AND D. J. EVANS' From the Department of Morbid Anatomy, Postgraduate Medical School, London
More informationBLIZARD INSTITUTE CORE PATHOLOGY ATLAS OF TINCTORIAL STAINS
BLIZARD INSTITUTE CORE PATHOLOGY ATLAS OF TINCTORIAL STAINS Contents Introduction... 3 Background to Tinctorial Stains... 3 Haematoxylin and Eosin Stain (H&E)... 3 Connective Tissue Stains... 4 Nucleic
More informationThis is Learning Component 6 in Learning Module 1. We will show examples of features ( things ) including mineral deposits, urates, pigments, dust,
This is Learning Component 6 in Learning Module 1. We will show examples of features ( things ) including mineral deposits, urates, pigments, dust, plant material, and amyloid. 1 Calcium salts are the
More informationMorphological changes (accumulations) occur inside and outside cells
MIXED ACCUMULATIONS (DEGENERATIONS) Morphological changes (accumulations) occur inside and outside cells The group includes: - chromoproteins metabolism disturbances; - lipoproteins metabolism disturbances;
More informationHISTOLOGY Lecture TWO DR. ASHRAF SAID
HISTOLOGY Lecture TWO DR. ASHRAF SAID Start Of this lecture TISSUES TISSUE: A DEFINITION A group of connected and interdependent cells that cooperate to perform a specific function CONNECTIVE TISSUE The
More information03 Connective Tissue, Cartilage, Bone & Blood
03 Connective Tissue, Cartilage, Bone & Blood 03-001 Connective Tissue 03-01. Mesenchyme. Human embryo, H-E stain, x 160. Amniotic epithelium 03-02. Mucous connective tissue 1. Human umbilical cord, H-E
More informationThe basis of Disease
General Curriculum The basis of Disease ZHOU REN 周韧 Prof., M.D., Ph.D. Institute of Pathology & Forensic Medicine Department of Pathology & Patho-physiology Zhenjiang University Judicial Evidence & Evaluation
More informationPlace and role of the pathology in the medicine. Structure of pathology and methods of investigation
Place and role of the pathology in the medicine. Structure of pathology and methods of investigation Dr. Attila Zalatnai (Just for educational purposes) Without pathology there is no modern diagnostics!
More informationHistopathology: Cell necrosis and cytoplasmic accumulations
Histopathology: Cell necrosis and cytoplasmic accumulations These presentations are to help you identify basic histopathological features. They do not contain the additional factual information that you
More informationEpithelia will be discussed according to the following scheme: Type Number of layers Shape Line drawing. Squamous Cuboidal Columnar
Epithelia Epithelia will be discussed according to the following scheme: Type Number of layers Shape Line drawing Simple Squamous Cuboidal Columnar Covering and Lining epithelium Pseudostratified Stratified
More informationmonotonous, stippled, round, smoothcontoured nuclei and scanty acidophilic or
monotonous, stippled, round, smoothcontoured nuclei and scanty acidophilic or vacuolated cytoplasm. The cells are surrounded by a loose fibrillary stroma that is traversed by delicate capillaries. Ill
More informationCell injury, adaptation and death. Unite one Second Lab.
Cell injury, adaptation and death Unite one Second Lab. The two lung abscesses seen here are examples of liquefactive necrosis in which there is a liquid center in an area of tissue injury. One abscess
More informationPigments and accumulations
Pigments and accumulations Intracellular Accumulations Normal cellular constituent vs. abnormal substance Transient vs. permanent Harmless vs. toxic Cytoplasm vs. nucleus Cell produced vs. produced other
More informationLipid Histochemistry of Surgically Resected Adrenal. Glands in Hyperadrenocorticism
Lipid Histochemistry of Surgically Resected Adrenal Glands in Hyperadrenocorticism Hideo TSUCHIYAMA Department of Pathology, Nagasaki University School of Medicine, Nagasaki Recently, fresh adrenal tissue
More informationThe Oral Histology Series Series 5 Special Stains
The Oral Histology Series Series 5 Special Stains DAVID E. KLINGMAN, Lt Col, USAF, DC Views and opinions expressed are those of the author(s) and do not reflect official policy or position of the United
More informationBIOCHEMISTRY OF SKIN AND CONNECTIVE TISSUES
BIOCHEMISTRY OF SKIN AND CONNECTIVE TISSUES Sri Widia A Jusman Department of Biochemistry & Molecular Biology FMUI 1 2 SKIN Epidermis - horny layer (keratin-filled dead cells) - granular layer - spinous
More informationCell Overview. Hanan Jafar BDS.MSc.PhD
Cell Overview Hanan Jafar BDS.MSc.PhD THE CELL is made of: 1- Nucleus 2- Cell Membrane 3- Cytoplasm THE CELL Formed of: 1. Nuclear envelope 2. Chromatin 3. Nucleolus 4. Nucleoplasm (nuclear matrix) NUCLEUS
More informationLYMPH GLAND. By : Group 1
LYMPH GLAND By : Group 1 ANATOMY LYMPH NODE Lymphatic Organs Red bone marrow Thymus gland Lymph nodes Lymph nodules Spleen Primary organs Secondary organs Lymph Nodes Firm, smooth-surfaced, bean-shaped
More informationskin generally-a very obvious disadvantage for the small bowel, the lymph nodes and in various other internal organs. Jopling5 has reviewed the
Journal of Neurology, Neurosurgery, and Psychiatry, 1981, 44. 116-120 Intra-neural ceroid-like pigment following the treatment of lepromatous leprosy with clofazimine (B663; Lamprene) A C McDOUGALL AND
More informationMT09 - Normal Human Tissue Microarray, FDA
Reveal Biosciences offers Histochemical Staining, Immunohistochemistry (IHC), In Situ Hybridization (ISH), Whole Slide Imaging, and Quantitative Image Analysis on any TMA MT09 - Normal Human Tissue Microarray,
More informationUnderstanding Skin Colour
Understanding Skin Colour SKIN COLOUR The natural colour of skin without any pigments is yellowish. However, we are all aware of the different colours of skin and these differences are determined by the
More informationTyrosinase Activity in the Pigmented Cells of the Nucleus Substantiae Nigrae. I. Monophenolase and Diphenolase Activity. By C. D.
4 7 Tyrosinase Activity in the Pigmented Cells of the Nucleus Substantiae Nigrae. I. Monophenolase and Diphenolase Activity By C. D. MARSDEN (From the Department of Anatomy, St. Thomas's Hospital Medical
More informationPATHOLOGY Intracellular Degeneration LAB 1
PATHOLOGY Intracellular Degeneration LAB 1 Cellular swelling Liver Organ :- Liver Lesion :- 1. Narrowing of hepatic sinusoids due to the swelling of hepatocyte. 2. The cytoplasm of affected hepatocyte
More informationA Single Neuron from the Brain
Nervous Tissue A Single Neuron from the Brain Dendrites Cell Body Axon Nerve cells, called neurons, transmit signals throughout our bodies. These signals tell our bodies what to do. Dendrites transmit
More informationA functioning black adenoma of the adrenal cortex:
J. clin. Path., 1974, 27, 955-959 A functioning black adenoma of the adrenal cortex: A clinico-pathological entity J. W. VISSER, J. K. BOEIJINGA, AND C. v.d. MEER From the Pathologisch Institwut and Department
More information4. Lysosomes, Smooth Endoplasmic Reticulum, Mitochondria, and Inclusions
4. Lysosomes, Smooth Endoplasmic Reticulum, Mitochondria, and Inclusions Undergraduate Graduate Histology Lecture Series Larry Johnson, Professor Veterinary Integrative Biosciences Texas A&M University
More informationHistopathology: skin pathology
Histopathology: skin pathology These presentations are to help you identify, and to test yourself on identifying, basic histopathological features. They do not contain the additional factual information
More informationCells Tissues Organs Organ Systems Organism. Cells: the smallest unit of life.
Cells Tissues Organs Organ Systems Organism Cells: the smallest unit of life. The Circulatory Systems brings oxygen, nutrients and hormones to cells; fights infections; removes cell wastes; regulates
More informationHematology Unit Lab 1 Review Material
Hematology Unit Lab 1 Review Material - 2018 Objectives Laboratory instructors: 1. Assist students during lab session Students: 1. Review the introductory material 2. Study the case histories provided
More informationEpithelial Tissues. Types of Epithelial Tissues: Lining of Kidney
Epithelial Tissues Covers the entire body surface and most of the body s inner cavities Outer epidermis (skin) protects from injury and drying out Inner epidermal tissue (on internal surfaces) often serves
More informationTissue = groups of cells that are similar in structure and function
Tissue = groups of cells that are similar in structure and function Types Epithelial - covering Connective - support Muscle - movement Nervous - control Membranes line body cavities and hold organs together
More informationA HISTOCHEMICAL AUTORADIOGRAPHIC METHOD FOR DEMON- STRATION OF TYROSINASE IN HUMAN MELANOCYTES, NEVI AND MALIGNANT MELANOMA*
A HISTOCHEMICAL AUTORADIOGRAPHIC METHOD FOR DEMON STRATION OF TYROSINASE IN HUMAN MELANOCYTES, NEVI AND MALIGNANT MELANOMA* THOMAS B. FITZPATRICK, M.D., PHI). AND ATSUSHI KUI{ITA, KUKITA, M.T). Ml). Numerous
More informationLymph I: The Peripheral Lymph System
Lymph I: The Peripheral Lymph System Peripheral = Secondary Primary Immune Organs = bone marrow, thymus Site of maturation of cells of the immune system Secondary Immune Organs = Nodes, MALT, spleen Filter
More informationDiagnostic Value of Fluorescence Method on Melanoma in Dogs
Jpn J Vet Dermatol 2003; 9 (4): 159 164 Diagnostic Value of Fluorescence Method on Melanoma in Dogs Masahiko Nagata 1), Atsuhiko Hasegawa 2) 1) Animal Dermatology Center, ASC 2) Department of Pathobiology,
More information2014 CURRENT ISSUES IN PATHOLOGY
2014 CURRENT ISSUES IN PATHOLOGY SPECIAL STAINS IN LIVER BIOPSY PATHOLOGY Sanjay Kakar, MD University of California, San Francisco Trichrome stain : (1) Assess degree of fibrosis. H&E stain is not reliable
More informationAtlas of Stains. Special Stains on Artisan Link Pro
Atlas of Stains Special Stains on Artisan Link Pro Intended use Routinely processed samples (paraffin-embedded) may be used. The preferred fixative is neutral buffered formalin. The clinical interpretation
More informationMedical School Histology Basics Introduction to Microscopy. VIBS 289 lab
Medical School Histology Basics Introduction to Microscopy VIBS 289 lab Larry Johnson Texas A&M University Objectives Learn the difference in magnification and resolution Learn about different types of
More informationHISTOPATHOLOGY. Introduction
HISTOPATHOLOGY Introduction Contacts Services offered Pathology tissue request Laboratory hours Special instructions Histopathology reports List of specimens Introduction The Histopathology section of
More informationImmune Surveillance. Immune Surveillance. Immune Surveillance. Neutrophil granulocytes Macrophages. M-cells
he immune system is everywhere Some organs have developed strategies towards the immune system to keep it out or to put it under control Immune privileged organs: Brain Eye estis hyroid gland Humoral immunity
More informationSaito, Yutaka; Tsuchiyama, Hideo. Citation Acta medica Nagasakiensia. 1988, 33
NAOSITE: Nagasaki University's Ac Title Author(s) Histochemical Nature of Eosinophili Adrenal Medulla Kawai, Kioko; Senba, Masachika; Shi Yoshida, Kuniko; Nakatani, Akira; K Saito, Yutaka; Tsuchiyama,
More informationDescribe the functions of the vertebrate integumentary system. Discuss the structure of the skin and how it relates to function.
Chapter 5 Describe the functions of the vertebrate integumentary system. Discuss the structure of the skin and how it relates to function. Explain the basis for different skin colors. Describe the structure
More informationSkin. Kristine Krafts, M.D.
Skin Kristine Krafts, M.D. Skin Lecture Objectives Describe the functions of skin. Describe the structure, location and function of the cell types found in epidermis: keratinocytes, melanocytes, Langerhans
More informationIT has been shown (Chou, 1957 a, b) that there are three kinds of lipid
279 The Ultra-fine Structure of Lipid Globules in the Neurones of Helix aspersa By J. T. Y. CHOU and G. A. MEEK (From the Cytological Laboratory, Department of Zoology; and Department of Human Anatomy,
More informationSchedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK
Schedule of Accreditation 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK Department of Eye Pathology 1 st Floor, Cayton Street Building UCL Institute of Ophthalmology 11-43 Bath Street
More informationSlide 74: Pituitary (Masson s trichrome)
histo074 Slide 74: Pituitary (Masson s trichrome) Infundibular stalk Pars tuberlaris Carcinoma Pars nervosa Pars intermedia Pars distalis Pars distalis Pars intermedia Pars nervosa Pars Pars intermedia
More informationSheet #7. Dr. Heba Kalbouneh. Dr. Heba Kalbouneh. Dr. Heba Kalbouneh
Sheet #7 Dr. Heba Kalbouneh Dr. Heba Kalbouneh Dr. Heba Kalbouneh Connective tissue The differences between epithelial and connective tissue - Epithelial cells are tightly packed (no or minimal spaces
More information11/8/2012. Chapter 6 Part 1 Objectives: Skin = Integument = Cutaneous Membrane. The Structure of Skin. Epidermis
Chapter 6 Part 1 Objectives: Define organ, and associate the skin as an organ of the integumentary system. List the general functions of the skin. Describe the structure of the layers of the skin. Summarize
More informationFunction Alimentary Canal
THE DIGESTIVE SYSTEM Function: to help convert food into simpler molecules that can be absorbed and used by the cells of the body. Alimentary Canala one way tube that passes through the body. (found in
More informationFig. 59 Malignant phaeochromocytoma, hepatic metastasis.
Fig. 59 Malignant phaeochromocytoma, hepatic metastasis. X 120 Hyperte nsion Fig. 60 Malignant sympathetic paraganglioma, lymph node metastasis Primary in bladder. x 1 20 Hypertension Fig. 61 Malignant
More information(A) Anemia (B) Malaria (C) Dehydration due to excess fluid loss. A. Incorrect! Anemia is symptomatic of sickle cell anemia, but is not the root cause.
USMLE Step 1- Problem Drill 13: Histology Question No. 1 of 10 1. An 8 year old male complains of fatigue and dactylitis, and has a history of recurrent bacterial infections. Examination of a blood smear
More informationEpithelial tumors. Dr. F.F. Khuzin, PhD Dr. M.O. Mavlikeev
Epithelial tumors Dr. F.F. Khuzin, PhD Dr. M.O. Mavlikeev Epithelial tumors Tumors from the epithelium are the most frequent among tumors. There are 2 group features of these tumors: The presence in most
More informationThe Egyptian journal of hospital medicine (2009)vol.,36:
The Egyptian journal of hospital medicine (2009)vol.,36: 468-482 QUANTITATIVE AND HISTOCHEMICAL STUDY ON THE ADRENAL MEDULLA IN POST NATAL PERIOD OF ALBINO RAT Wagieh k.baiomy; Abdel-mawgood Anas; Mamdooh
More informationPigmented lesions of the Oral cavity
Oral medicine أ.م.د احسان عبد هللا كميل Pigmented lesions of the Oral cavity Pigmented oral lesions are a large group of disorders in which the dark or brown color is the essential clinical characteristic.
More informationMelanin 6/22/2009. Group of compounds that serves predominantly as pigment.
Tessa Sinnige Liliana Joachín-Rodríguez Directed by: David Egan Melanin Group of compounds that serves predominantly as pigment. Pheomelanin (red/yellow) * Eumelanin (brown/black) * Neuromelanin (dark
More informationAnatomy and Physiology Homework: Chapters 3-4
Anatomy and Physiology Homework: Chapters 3-4 CHAPTER 3: Cells and Tissues 1. The smallest unit of living tissue is called a. All living organisms are composed of these basic units where all life processes
More informationCHAPTER 14 Bones, Muscles, Skin
CHAPTER 14 Bones, Muscles, Skin SECTION 1 Body Organization and Homeostasis Levels of Organization Basic to Complex Cells Tissues Organs Organ Systems CELLS Basic unit in living thing Main Parts: Cell
More informationlysosomes Ingested materials Defective cell components Degrades macromolecules of all types:
lysosomes Digests Ingested materials Defective cell components Degrades macromolecules of all types: Proteins Nucleic acids Carbohydrates Lipids Single membrane bound vesicle, contains up to 50 digestive
More informationChapter 1: Cells and Tissues
Chapter 1: Cells and Tissues Cells and Tissues Carry out all chemical activities needed to sustain life Cells are the building blocks of all living things Tissues are groups of cells that are similar in
More informationSkin and Body Membranes
4 Skin and Body Membranes PowerPoint Lecture Slide Presentation by Jerry L. Cook, Sam Houston University ESSENTIALS OF HUMAN ANATOMY & PHYSIOLOGY EIGHTH EDITION ELAINE N. MARIEB Skin and Body Membranes
More informationMalignant tumors of melanocytes: Part 1. Deba P Sarma, MD., Omaha
Malignant tumors of melanocytes: Part 1 Deba P Sarma, MD., Omaha The melanocytic tumor is one of the most difficult and confusing areas in Dematopathology. It is true that most (95%) of such lesions are
More informationLIVER & SPLEEN. Color index: Slides.. Important..Notes..Extra..
LIVER & SPLEEN Color index: Slides.. Important..Notes..Extra.. Objectives: By the end of this lecture, the student should be able to describe: 1. The histological structure of liver with special emphasis
More informationBody Tissues Pearson Education, Inc.
Body Tissues Tissues Groups of cells with similar structure and function Four primary types: Epithelial tissue (epithelium).1 Connective tissue.2 Muscle tissue.3 Nervous tissue.4 Epithelial Tissues Locations:
More informationCells and Tissues 3PART D. PowerPoint Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College
PowerPoint Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College Cells and Tissues 3PART D Connective Tissue Found everywhere in the body Includes the most abundant
More informationVITAMINS-FAT SOLUBLE [LIPPINCOTT S ] Deeba S. Jairajpuri
VITAMINS-FAT SOLUBLE [LIPPINCOTT S 381-394] Deeba S. Jairajpuri VITAMIN A othe term retinoids includes both natural and synthetic forms of vitamin A essential for vision, reproduction, growth and maintenance
More informationPATHOPHYSIOLOGY. DEFINED Involves the study of function that results from disease processes.
DEFINED Involves the study of function that results from disease processes. What is pathology? Pathology is the branch of medical sciences that treats the essential nature of disease, especially the changes
More informationJAUNDICE. Zdeněk Fryšák 3rd Clinic of Internal Medicine Nephrology-Rheumatology-Endocrinology Faculty Hospital Olomouc
JAUNDICE Zdeněk Fryšák 3rd Clinic of Internal Medicine Nephrology-Rheumatology-Endocrinology Faculty Hospital Olomouc Definition of Jaundice Icterus A yellowish staining of the skin, sclerae and deeper
More informationThey cells can not function death.
Jenna Hellack Jan 2001 Tissues What do you think happens when the cells use up their food and oxygen before there is time to replenish it? They cells can not function death. Blood Cell Cancer cell Plant
More informationAdrenergic agonists Sympathomimetic drugs. ANS Pharmacology Lecture 4 Dr. Hiwa K. Saaed College of Pharmacy/University of Sulaimani
Adrenergic agonists Sympathomimetic drugs ANS Pharmacology Lecture 4 Dr. Hiwa K. Saaed College of Pharmacy/University of Sulaimani 2017-2018 Adrenergic agonists The adrenergic drugs affect receptors that
More informationBilirubin Metabolism. Prof. Dr. Hedef Dhafir El-Yassin. 1 Prof. Dr. El-Yassin
Bilirubin Metabolism Prof. Dr. Hedef Dhafir El-Yassin 1 Prof. Dr. El-Yassin Objectives: 1. To outline the basic metabolic pathway of bilirubin breakdown and conjugation 2. To state the basic metabolic
More informationEssentials of Anatomy and Physiology, 9e (Marieb) Chapter 3 Cells and Tissues. Short Answer. Figure 3.1
Essentials of Anatomy and Physiology, 9e (Marieb) Chapter 3 Cells and Tissues Short Answer Figure 3.1 Using Figure 3.1, match the following: 1) The illustration of simple cuboidal epithelium is. Answer:
More informationCell Physiology
Cell Physiology 21-10-2018 1 The two major parts of a typical cell are the nucleus and the cytoplasm. The nucleus is separated from the cytoplasm by a nuclear membrane, and the cytoplasm is separated from
More informationExternal Neoplasms in Goats: A Clinicopathological Study on Five Types. Abu-Seida, A.M and Kawkab, A. Ahmed
External Neoplasms in Goats: A Clinicopathological Study on Five Types By Abu-Seida, A.M and Kawkab, A. Ahmed Introduction Introduction Neoplasia is occasionally diagnosed in goats. A survey of 800000
More informationSkin and Body Membranes Body Membranes Function of body membranes Cover body surfaces Line body cavities Form protective sheets around organs
Skin and Body Membranes Body Membranes Function of body membranes Cover body surfaces Line body cavities Form protective sheets around organs Classification of Body Membranes Epithelial membranes Cutaneous
More informationCONNECTIVE TISSUE (C.T.)
CONNECTIVE TISSUE (C.T.) Objectives: By the end of this lecture, the student should be able to: 1. Enumerate the general characteristics of C.T. 2. Classify C.T into C.T. proper and special types of C.T.
More informationSchedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK
2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK Cellular Pathology Department University College London Hospital Rockefeller Building University Street London WC1E 6JJ Contact: Gavyn Barrett
More informationAnatomy and Physiology
Anatomy and Physiology For The First Class 2 nd Semester Erythrocytes = Red Blood Cells (RBC) Erythrocytes = Red Blood Cells Red blood cells are biconcave discs, they have no nucleus and cytoplasmic organelles.
More informationSkin and Body Membranes
Essentials of Human Anatomy & Physiology Elaine N. Marieb Seventh Edition Chapter 4 Skin and Body Membranes Slides 4.1 4.32 Lecture Slides in PowerPoint by Jerry L. Cook Skin and Body Membranes Function
More informationBasophilic. Basophilic structures are stained by basic dyes: Mnemonic: Basophilic = Blue
Cell Overview Basophilic Basophilic structures are stained by basic dyes: Basic dyes are positive Basophilic structures are negative (ex. DNA, RNA, ribosomes, RER) Mnemonic: Basophilic = Blue Acidophilic
More informationLYMPHOID ORGANS. Dr. Iram Tassaduq
LYMPHOID ORGANS Dr. Iram Tassaduq COMPONENTS OF IMMUNE SYSTEM Lymphocytes Diffuse Lymphatic Tissue Lymphatic Nodules Lymph node Spleen Bone marrow Thymus Functions of Immune System Has the ability to distinguish
More informationBlood & Blood Formation
Module IB Blood & Blood Formation Histology and Embryology Martin Špaček, MD (m.spacek@centrum.cz) http://www.lf3.cuni.cz/histologie Approximately 7% of a person's weight is blood (about 5 L) Blood consists
More informationThe intracellular origin of the melanosome in pigment cells. A review of ultrastructural data
Histol Histopathol (1 996) 1 1 : 445-462 Histology and Histopathology ln vited Re vie w The intracellular origin of the melanosome in pigment cells. A review of ultrastructural data U. Schraermeyer Institut
More informationHypopigmenting agents
An in-depth review on the biological and chemical aspects of hyperpigmentation and contemporary strategies for achieving even skin tone Hypopigmenting agents Melanin Pigment that provides color to skin,
More informationChapter 2 Cell. Zhou Li Prof. Dept. of Histology and Embryology
Chapter 2 Cell Zhou Li Prof. Dept. of Histology and Embryology The inner life of the cell Ⅰ. Plasma membrane (Plasmalemma) 1.1 The structure Unit membrane: inner layer 3-layered structure outer layer mediat
More informationPRACTICAL ROADMAP. GLANDS AFFECTING LIFESTYLE WJ van der Spuy & T Tshabalala
PRACTICAL ROADMAP GLANDS AFFECTING LIFESTYLE WJ van der Spuy & T Tshabalala GLANDS AFFECTING LIFESTYLE Submandibular gland (salivary gland) Liver Pancreas Hypophysis (pituitary gland) Thyroid Suprarenal
More informationCONNECTIVE TISSUE Histology BY Dr Navneet Kumar Professor Anatomy KGMU LKO
CONNECTIVE TISSUE Histology BY Dr Navneet Kumar Professor Anatomy KGMU LKO CONNECTIVE TISSUE INTRODUCTION Connective tissue is one which gives structural and metabolic support to the organ and other tissue
More informationPowerPoint Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College Skin and Body Membranes
PowerPoint Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College Skin and Body Membranes 4 Body Membranes Function of body membranes Cover body surfaces Line body cavities
More informationIntegumentary System
Integumentary System The integumentary system is commonly known as the Skin Largest organ of human body 10% total body weight and would cover over 20 square feet Functions of Skin 1. Protection Barrier
More informationIntegumentary System. Packet #12
Integumentary System Packet #12 Introduction Skin/Integument Skin, considered an organ, is the major component of the integumentary system. The integumentary system is also composed of other accessory
More informationHormones and the Endocrine System Chapter 45. Intercellular communication. Paracrine and Autocrine Signaling. Signaling by local regulators 11/26/2017
Hormones and the Endocrine System Chapter 45 Intercellular communication Endocrine signaling Local regulators Paracrine and autocrine signaling Neuron signaling Synaptic and neuroendocrine signaling Paracrine
More informationOLIGOPHRENIA BY J. H. FELLMAN*
J. Neurol. Neurosurg. Psychiat., 1958, 21, 58. EPINEPHRINE METABOLITES AND PIGMENTATION IN THE CENTRAL NERVOUS SYSTEM IN A CASE OF PHENYLPYRUVIC OLIGOPHRENIA BY J. H. FELLMAN* From the Division of Neurology,
More informationHistopathology: gastritis and peptic ulceration
Histopathology: gastritis and peptic ulceration These presentations are to help you identify, and to test yourself on identifying, basic histopathological features. They do not contain the additional factual
More informationPreface 1. Fixation and Processing 1
Contents Preface xi 1. Fixation and Processing 1 Fixation 1 Processing 2 What Should Be Seen in a Well-Fixed, Well-Processed Specimen Stained with Hematoxylin and Eosin 3 Problems Encountered With Fixation
More informationC.L. Davis Foundation Descriptive Veterinary Pathology Course
C.L. Davis Foundation 2015 Descriptive Veterinary Pathology Course IHC Resources IHC Identification Targets Antibodies Antibodies 1 Antibodies Specimens Antigen Retrieval Unmasks antigen epitopes Methods
More informationHistopathology: chronic inflammation
Histopathology: chronic inflammation These presentations are to help you identify, and to test yourself on identifying, basic histopathological features. They do not contain the additional factual information
More information