Atherosclerosis Mechanisms and novel therapeutic targets International Symposium

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1 Atherosclerosis Mechanisms and novel therapeutic targets International Symposium October 5-6, 2016 Carl Friedrich von Siemens Foundation Nymphenburg Palace, Munich Generously supported by:

2 Wednesday, :00 09:10 Welcome address Christian Weber Speaker of SFB 1123 (Munich, Germany) Session I: Danger in atherosclerosis Chairs: Jürgen Bernhagen & Peter Düwell 09:10-09:35 Eicke Latz Rheinische Friedrich-Wilhelms-Universität, Bonn, Germany Regulation of atherosclerosis by the NLRP6 inflammasome 09:35-10:00 Konstantin Stark Death signals in atherosclerosis and thrombosis 10:00-10:25 Oliver Söhnlein Kiss of death: NETs kill smooth muscle cells to induce plaque destabilization 10:25-10:40 Almudena Ortega Novel strategies to boycott myeloid cell recruitment 10:40-11:10 Coffee break Session II: Inflammation networks Chairs: Markus Moser & Maik Drechsler 11:10-11:50 Paul Frenette Albert Einstein College of Medicine, New York, USA Role of arterioles in hematopoiesis 11:50 12:30 Andres Hidalgo Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain Time as a parameter in neutrophil biology 12:30-12:55 Yvonne Döring Vascular Cxcr4 in atherosclerosis 12:55-13:10 Johan Duchene Darc side of hematopoiesis 13:10-14:10 Lunch Session II: Inflammation networks cont d Chairs: Sabine Steffens & Steffen Massberg 14:10-14:50 Guo-Ping Shi Harvard Medical School, Boston, USA The role of the Na-CI co-transporter in cardiovascular biology 14:50-15:30 Matthias Nahrendorf Harvard Medical School, Boston, USA Inflammatory networks in ischemic heart disease

3 15:30-15:55 Christian Weber Chemokine interactome as novel therapeutic target 15:55-16:10 Michael Horckmans The CB2/2-AG axis in post-myocardial infarction leukocyte mobilization 16:10-16:40 Coffee break 16:40-18:40 Poster session, networking Moderated poster session A Projects: Ziad Mallat, Matthias Nahrendorf, Paul Frenette B Projects: Manual Mayr, Timothy Hla, Garret FitzGerald From 19:00 Palmenhaus Poster awards Thursday, Session III: Lipids and lipid mediators in atherosclerosis Chairs: Heribert Schunkert & Wolfgang Siess 09:00-09:40 Timothy Hla Weill Medical College of Cornell University, New York, USA HDL-bound sphingosine 1-phosphate biology 09:40-10:20 Garret FitzGerald University of Pennsylvania, Philadelphia, USA Eicosanoids and their inhibitors 10:20-10:45 Susanna Hofmann T3 targeting via glucagon transport offers metabolic benefits without thyrotoxicity 10:45-11:00 Emiel van der Vorst HDL and macrophages an unexpected combination 11:00-11:30 Coffee break Session IV: Nucleotides in atherosclerosis Chairs: Philipp von Hundelshausen & Daniel Teupser 11:30-12:20 Manuel Mayr King s College, London, UK Circulating mirnas: Evolving players in the field of medicine 12:20 12:45 Andreas Schober Cell type-specific role of Dicer in atherosclerosis and neointima formation

4 12:45-13:00 Donato Santovito Differential trafficking of mir-126 strands in atherosclerosis 13:00-14:00 Lunch Session IV: Nucleotides in atherosclerosis cont d Chairs: Martin Dichgans & Bernd Engelmann 14:00-14:25 Thorsten Kessler Technische Universität - Deutsches Herzzentrum, Munich, Germany Functional characterization of the GUCY1A3 coronary artery disease risk locus 14:25 14:50 Lesca Holdt Mechanisms of long non-coding RNA ANRIL in atherosclerosis 14:50-15:05 Lucia Natarelli mirna-regulated IncRNAs in endothelial regeneration during atherosclerosis 15:05-15:20 Yaw Asare HDAC9: a master regulator of vascular inflammation 15:20-15:50 Coffee break Session V: Imaging and Immunity Chairs: Esther Lutgens & Remco Megens 15:50-16:30 Zahi Fayad Ican School of Medicine at Mount Sinai, New York, USA Imaging and Nanomedicine in inflammatory atherosclerosis 16:30 17:10 Ziad Mallat University of Cambridge, Cambridge, UK Role of B lymphocyte responses in atherosclerosis and ischemic injury 17:10 17:35 Norbert Gerdes CD27 co-stimulation promotes Treg survival and ameliorates atherosclerosis 18:00-19:00 SFB1123 General Assembly

5 Schlosscafé Palmenhaus Carl Friedrich von Siemens Stiftung TRAMs to City Center, 16, 17, N16 Hotel Laimer Hof Symposium Venue: Carl Friedrich von Siemens Stiftung Südliches Schlossrondell 23, Munich Hotel: Hotel Laimer Hof, Laimer Straße 40, Munich, +49 (0) Social Dinner (Wednesday evening 7 p.m.): Schlosscafé im Palmenhaus, Schloss Nymphenburg 43, München

DECLARATION OF CONFLICT OF INTEREST. No disclosures

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