2. What is molecular oxygen directly converted into? a. Carbon Dioxide b. Water c. Glucose d. None of the Above

Transcription

1 Biochem 1 Mock Exam 3 Chapter 11: 1. What is glucose completely oxidized into? a. Carbon Dioxide and Water b. Carbon Dioxide and Oxygen c. Oxygen and Water d. Water and Glycogen 2. What is molecular oxygen directly converted into? a. Carbon Dioxide b. Water c. Glucose d. None of the Above 3. Where DOESN T the malate- aspartate shuttle system work? a. Liver Mitochondria b. Kidney Mitochondria c. Heart Mitochondria d. Skeletal Muscle Mitochondria 4. Where does oxidative phosphorylation take place? a. Cytosol b. Golgi Bodies c. Mitochondira d. None of the Above 5. Oxaloacetate is converted into by, thus making it able to travel across the membrane to the. a. Aspartate, Alpha- Ketoglutarate, Matrix b. Aspartate, Glutamate, Cytosol c. Malate, Glutamate, Matrix d. Malate, Alpha- Ketoglutarate, Cytosol 6. Glycerol- 3- Phosphate Dehydrogenase converts what into Glycerol- 3- Phosphate? a. Dihydroxyacetone Phosphate b. Dihydroxyacetone Glycerol c. Dihydroxyacetone Kinase d. Dihydroxyacetone Hydroxyl 7. What is another name for Ubiquinone? a. Cytochrome A b. Cytochrome B c. Cytochrome C d. Cytochrome Q

2 8. Which of the following is the correct sequence for the Electron Transport Chain? a. NADH à CoQ à Cyt A à Cyt A3 à Cyt B à Cyt C à Cyt C1 à O2 b. NADH à Cyt A à Cyt A3 à Cyt B à Cyt C à Cyt C1 à CoQ à O2 c. NADH à CoQ à Cyt B à Cyt A à Cyt A3 à Cyt C1 à Cyt C à O2 d. NADH à CoQ à Cyt B à Cyt C1 à Cyt C à Cyt A à Cyt A3 à O2 9. What is another name for Complex I? a. NADH Dehydrogenase b. NADH Rehydrogenase c. FADH2 Dehydrogenase d. FADH2 Rehydrogenase 10. Which Complex in the Electron Transport Chain does not pump a proton through to contribute to the proton gradient? a. Complex I b. Complex II c. Complex III d. Complex IV 11. What does Retinone block the production of? a. NADH b. CoQ c. Cytochrome C1 d. O2 12. The passage of how many protons creates 1 ATP? a. 1 b. 2 c. 3 d What is the name of the enzyme that exergonically pumps protons back into the matrix? a. Proton ATPase b. ATP Synthase c. Both A and B d. Neither A nor B 14. What is the Fo subunit of Complex 5 blocked by? a. Rotenone b. Antimycin A c. Oligomycin d. Fumarate

3 15. Select the two uncoulplers of oxidative phosphorylation MACA a. 2,4- Dinitrophenol b. 1,3- Biaminoacetone c. FCCP d. PCCF 16. What is the name of the protein that babies have that acts as an uncoupler of Oxidative phosphorylation? a. Thermopremin b. Thermogenin c. Thermorenin d. Thermostenin Chapter 12: 17. What is sucrose a combination of? a. Glucose and Fructose b. Glucose and Galactose c. Glucose and Maltose d. Galactose and Fructose 18. Fructose is converted to which of the following compound in liver tissue before it enters the glycolytic pathways a. Fructose- 6- Phosphate b. Fructose 1,6- Bisphosphate c. Glucose 6- Phosphate d. Fructose- 1- Phosphate 19. What is the function of galactokinase? a. Galactose à Galactose- 6- Phosphate b. Galactose à Galactose- 1- Phosphate c. Galactose- 1- Phosphate à Glucose- 1- Phosphate d. Glucose- 1- Phosphate à Galactose- 1- Phosphate 20. Mannose is converted to what by hexokinase? a. Mannose- 6- Phosphate b. Mannose- 1- Phosphate c. Fructose- 6- Phosphate d. Fructose- 1- Phosphate

4 21. Pentose phosphate pathway is: a. A reductive pathway b. A process that synthesizes glucose c. An oxidative pathway to metabolize pyruvate d. An oxidative pathway to metabolize glucose and/or glucose- 6- phosphate 22. What enzyme forms the second molecule of NADPH? a. Glucose- 6- Phosphate Dehydrogenase b. 6- Phosphoglucono- delta- lactone Dehydrogenase c. Transketolase d. Transaldolase 23. Wernicke- Korsakoff syndrome is caused by a deficiency of what? a. Biotin b. Thiamine c. Lactose d. NADPH Chapter 13: 24. What tissue stores the majority of glycogen in our bodies/ a. Muscle b. Stomach c. Liver d. Gall Bladder 25. What triggers glycogen breakdown in the liver? a. Need for ATP b. High blood glucose c. High ATP d. Low blood glucose 26. Glucose is added to end of a glycogen chain? a. Reducing end b. Non- reducing end c. Alpha- 1,4 Linkages 27. What is the coenzyme used for the enzyme Glycogen Phosphorylase? a. Thiamine b. Pyridoxal Phosphate c. Biotin d. Calcium

5 28. What is removed from the alpha 1,6- linkage of glycogen by Glycogen debranching enzyme? a. Glucose b. Glucose- 6- Phosphate c. Glucose- 1- Phosphate d. Fructose- 6- Phosphate 29. What transporter takes cytosolic glucose to the circulation? a. Glucose- 6- Phosphatase b. Glucose- 6- Phosphate Transporter c. GLUT 1 d. GLUT Which of the following is NOT an allosteric inhibitor of Glycogen Phosphorylase? a. ATP b. Glucose- 6- Phosphate c. AMP d. Glucose 31. What kind of bond is formed between the glucose of UDP- glucose and Tyr- residue of glycogenin protein? a. Glycosidic b. Glucosidic c. Glycodimic d. Glucodimic 32. What is the defective enzyme in von Gierke s disease? a. Hexokinase b. Glucose- 6- Phosphate Dehydrogenase c. Glucose- 6- Phosphatase d. Glucokinase 33. What is the result of Andersen s disease? a. Absence of debranching enzyme b. Diminished tolerance to exercise c. Accumulation of less- branched enzymes d. Muscular dystrophy 34. What is the metablic link between glycogenesis and Glycolysis? a. Glucose b. Pyruvate c. Acetyl CoA d. Glucose- 1- Phosphate

6 Chapter 14: 35. What two cells in the body cannot survive without glucose? a. Nervous system and heart b. Nervous system and muscle c. Nervous system and Red blood cells d. Nervous system and Lymphatic tissue 36. Which of the following is NOT a major substrate for Gluconeogenesis? a. Lactate b. Glycerol c. Succinate d. Acetyl CoA 37. Under what condition do we need to perform gluconeogenesis? a. Starvation b. High carbohydrate diet c. Low intensity exercise d. Both B & C 38. When performing a transamination reaction, what is Aspartate a precursor for? a. Pyruvate b. Oxaloacetate c. Alpha- keto- glutarate d. Glucose- 6- Phosphate 39. Some reactions steps in the glycolytic pathway are bypassed in gluconeogenesis. Which of the following enzymes in the gluconeogenesis pathway bypasses one such enzyme in glycolysis? a. Phosphofructokinase- 1 b. Glucokinase c. Pyruvate Kinase d. Fructose- 1,6- Bisphosphatase Which enzyme converts pyruvate into oxaloacetate? What coenzyme is used in this reaction? a. Pyruvate Carboxylase; TPP b. Pyruvate Carboxylase; Biotin c. Mitochondrial PEP Carboxykinase; TPP d. Mitochondrial PEP Carboxykinase; Biotin 41. How many moles of ATP are required for gluconeogenesis? a. 2 b. 3 c. 4 d. 6

7 42. What is the principal allosteric regulator of glycolysis and gluconeogenesis? a. Fructose 2,6- bisphosphatase b. Fructose 1,6- bisphoshatase c. Glucose- 6- phosphate d. Glucose- 1- phoshate 43. What enzyme catalyzes the oxidation of ethanol to acetaldehyde? a. Alcohol hydrogenase b. Alcohol dehydrogenase c. Acetaldehyde Hydrogenase d. Acetaldehyde Dehydrogenase 44. T/F: NADH/NAD+ ratio is increased in alcohol consumption? 45. Microsomal Ethanol Oxidizing System (MEOS) generates acetaldehyde using what Reducing agent? a. NADPH b. NADH c. NADP+ d. NAD+ 46. Which of the following is an effect of alcoholism? a. Fatty liver b. Liver cirrhosis c. Death d. All of the Above 47. Which of the following enzymes is used in both Glycolysis and Gluconeogenesis? a. Hexokinase b. Aldolase c. Phosphofructokinase- 1 d. Pyruvate Carboxylase 48. Sdf 49. Sdf 50.