National, regional, and global trends in metabolic risk factors. Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group

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1 National, regional, and global trends in metabolic risk factors Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group

2 Citations Danaei G,* Finucane MM,* Lin JK,* Singh GM,* Paciorek CJ, Cowan MJ, Farzadfar F, Stevens GA, Lim SS, Riley LM, Ezzati M, on behalf of the Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Pressure). National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5 4 million participants. Lancet 2011; published online Feb 4. DOI: /S (10) Finucane MM,* Stevens GA,* Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, Farzadfar F, Riley LM, Ezzati M, on behalf of the Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Body Mass Index). National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9 1 million participants. Lancet 2011; published online Feb 4. DOI: /S (10) Farzadfar F,* Finucane MM,* Danaei G, Pelizzari PM, Cowan MJ, Paciorek CJ, Singh GM, Lin JK, Stevens GA, Riley LM, Ezzati M, on behalf of the Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Cholesterol). National, regional, and global trends in serum total cholesterol since 1980: systematic analysis of health examination surveys and epidemiological studies with 321 country-years and 3 0 million participants. Lancet 2011; published online Feb 4. DOI: /S (10) *co-first authors

3 Study objective To estimate trends for three major metabolic risk factors for chronic diseases by age, sex, and country/region between 1980 and 2008 Body mass index (BMI) Systolic blood pressure (SBP) Serum total cholesterol (TC) To quantify the uncertainty of the estimates

4 Data access flowchart (SBP) 324 health surveys and epidemiologic studies analyzed by Collaborating Group members representing 380 country-years 3 multi-center epidemiologic studies representing 169 country-years 14,763 articles identified in Medline and Embase 10,682 articles excluded based on title and abstract review 4,081 articles remaining after exclusion based on title and abstract review 2,113 articles excluded based on full text review and 285 articles excluded because we could not retrieve the full-text or because we could not translate the article 1,683 articles remaining after exclusion based on full text review 3 articles received through personal communication 1,543 articles excluded because data were not accessible by age and sex, because they were based on the same study as another article, or because the same data were available from Collaborating Group members Data extracted from 143 published studies representing 198 country-years 39 additional country-years of data retrieved from WHO Global Infobase Danaei et al. Lancet 2011 Data extracted for 786 countryyears with 5.4 million participants

5 Data access flowchart (TC) 149 health surveys and epidemiologic studies analyzed by Collaborating Group members representing 204 country-years 1 multi-center epidemiologic study representing 59 country-years 8,246 articles identified in Medline and Embase 5642 articles excluded based on title and abstract review 2,604 articles remaining after exclusion based on title and abstract review 631 articles remaining after exclusion based on full text review Data extracted from 41 published studies representing 52 country-years 1948 articles excluded based on full text review and 25 articles excluded because we could not retrieve the full-text or because we could not translate the article 590 articles excluded because data were not accessible by age and sex, because they were based on the same study as another article, or because the same data were available from Collaborating Group members 6 additional country-years of data retrieved from WHO Global Infobase Farzadfar et al. Lancet 2011 Data extracted for 321 countryyears with 3.0 million participants

6 Data access flowchart (BMI) 425 health surveys and epidemiologic studies analyzed by Collaborating Group members representing 529 country-years 3 multi-center epidemiologic studies representing 175 country-years 7,219 articles identified in Medline and Embase 3,207 articles excluded based on title and abstract review 4,012 articles remaining after exclusion based on title and abstract review 2,088 articles excluded based on full text review and 279 articles excluded because we could not retrieve the full-text or because we could not translate the article 1,645 articles remaining after exclusion based on full text review 3 reports with 4 countryyears received through personal communication 1,502 articles excluded because data were not accessible by age and sex, because they were based on the same study as another article, or because the same data were available from Collaborating Group members Data extracted from 146 published studies representing 181 country-years 75 additional country-years of data retrieved from WHO Global Infobase Finucane et al. Lancet 2011 Data extracted for 960 countryyears with 9.1 million participants

7 Danaei et al. Lancet 2011 SBP data availability (all data)

8 Danaei et al. Lancet 2011 SBP data availability (national data)

9 Finucane et al. Lancet 2011 BMI data availability (all data)

10 BMI data availability (national data, male) Finucane et al. Lancet 2011

11 BMI data availability (national data, female) Finucane et al. Lancet 2011

12 Farzadfar et al. Lancet 2011 TC data availability (all data)

13 Farzadfar et al. Lancet 2011 TC data availability (national data)

14 Danaei et al. Lancet 2011 SBP data availability by year and region

15 Farzadfar et al. Lancet 2011 TC data availability by year and region

16 BMI data availability by year and region (male) Finucane et al. Lancet 2011

17 BMI data availability by year and region (female) Finucane et al. Lancet 2011

18 Age-standardized mean SBP in 2008 Men Women Danaei et al. Lancet 2011

19 World trends in age-standardized mean SBP Women Men Danaei et al. Lancet 2011

20 SBP trends in high-income regions (men) North America Australasia Asia-Pacific Western Europe Danaei et al. Lancet 2011

21 SBP trends in high-income regions (women) North America Australasia Asia-Pacific Western Europe Danaei et al. Lancet 2011

22 SBP trends in selected regions (men) East Asia Central Latin America South Asia East Africa Danaei et al. Lancet 2011

23 SBP trends in selected regions (women) East Asia Central Latin America South Asia East Africa Danaei et al. Lancet 2011

24 Danaei et al. Lancet 2011 Change in SBP in 199 countries (men)

25 Danaei et al. Lancet 2011 Change in SBP in 199 countries (women)

26 Age-standardized mean BMI in 2008 Men Women Finucane et al. Lancet 2011

27 World trends in age-standardized mean BMI Women Men Finucane et al. Lancet 2011

28 BMI trends in high-income regions (men) North America Australasia Asia-Pacific Western Europe Finucane et al. Lancet 2011

29 BMI trends in high-income regions (women) North America Australasia Asia-Pacific Western Europe Finucane et al. Lancet 2011

30 BMI trends in selected regions (men) East Asia South Asia Central Europe North Africa and Middle East Finucane et al. Lancet 2011

31 BMI trends in selected regions (women) East Asia South Asia Central Europe North Africa and Middle East Finucane et al. Lancet 2011

32 Finucane et al. Lancet 2011 Change in BMI in 199 countries (men)

33 Finucane et al. Lancet 2011 Change in BMI in 199 countries (women)

34 Age-standardized mean TC in 2008 Men Women Farzadfar et al. Lancet 2011

35 World trends in age-standardized mean TC Women Men Farzadfar et al. Lancet 2011

36 TC trends in high-income regions (men) North America Australasia Asia-Pacific Western Europe Farzadfar et al. Lancet 2011

37 TC trends in high-income regions (women) North America Australasia Asia-Pacific Western Europe Farzadfar et al. Lancet 2011

38 TC trends in selected regions (men) East Asia Southern Latin America Central Latin America Central Africa Farzadfar et al. Lancet 2011

39 TC trends in selected regions (women) East Asia Southern Latin America Central Latin America Central Africa Farzadfar et al. Lancet 2011

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