AVIAN HEMATOLOGY. MVDr. Zora Knotková, Ph.D. MVDr. Anna Hrdá, Ph.D.
|
|
- Elwin Wilcox
- 6 years ago
- Views:
Transcription
1 AVIAN HEMATOLOGY MVDr. Zora Knotková, Ph.D. MVDr. Anna Hrdá, Ph.D. Avian and Exotic Animal Clinic University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic
2 HEMATOLOGIC TESTS Form an excellent tool to evaluate the patient s general condition Monitor the progress of a disease Form a prognosis
3 HEMATOLOGIC EVALUATION Routine hematologic evaluation includes determination of Packed cell volume (PCV) Hemoglobin (Hb) concentration Red blood cell count (RBC) RBC indices (MCV, MCH, MCHC) Total white blood cell count (WBC) Leukocyte differential count (leukogram) Assessement of blood cell morphology
4 SAMPLE HANDLING In order to obtain objective results it is crucial to use appropriate methods of blood collection and handling with samples.
5 PREANALYTIC PHASE In this first phase, it is necessary: to prepare the patient and collection material collect and process the sample transport the sample and preserve it until analysis This phase have more than 50 % responsibility for correctness of results
6 BLOOD COLLECTION 0.2 ml sufficient for complete hemogram 1.0 ml/100 g body weight for healthy birds less in clinically sick patients be aware of iatrogenic blood loss due to hematoma formation after venipuncture
7 BLOOD COLLECTION Blood collection should be performed safely and quickly. Most birds, especially ill birds and small birds such as finches and canaries, are easily stressed when handled. The stress associated with capture and restraint of avian patient can further compromise the health of the patient and may affect the hematologic indices
8 VENIPUNCTURE v. jugularis dextra (jugular vein) v. cutanea ulnaris superficialis (wing vein) v. metatarsalis plantaris superficialis (caudal tibial vein) cardiac puncture puncture of the occipital venous sinus
9 ANTICOAGULANTS EDTA (ethylenediaminetetraacetic acid) HEPARIN (lithium heparin) artificial hemolysis due to EDTA reported in Corvidae, Gruidae, Strutionidae, Alcedinidae (Kookaburra)
10 ANALYTIC PHASE This second phase includes: preparation of the sample analysis itself Avian hematology is approached in a manner similar to the mammalian hematology, but a few differences in blood cell morphology require modification of the laboratory techniques
11 ANALYTIC PHASE Despite the technological progress in avian hematology, the evaluation of cell morphology and the interpretation of hematological results cannot be realized sufficiently by automated procedures.
12 ANALYTIC PHASE Major differences include the presence of nucleated erythrocytes, thrombocytes, and heterofil granulocytes in the peripheral blood of birds The modified procedures include the use of manual counting techniques to obtain accurate cell counts
13 Red blood cell count (RBC, /l) White blood cell count (WBC, 10 9 /l) Manual technique 4975 µl of Natt and Herrick s solution + 25 µl of blood (dilution 1:200) Bürker s chamber method Ery: 20 rectangles (1/100 mm 2 ) Leu: 50 squares (1/25 mm 2 )
14 PACKED CELL VOLUME (PCV) Centrifugation of blood in a heparinized micro-hematocrit tube at approximately g for 5 minutes
15 HEMOGLOBIN CONCENTRATION (g/l) Spectrophotometric analysis of cyanmethemoglobin at 540 nm Centifugation after red cell lysis necessary (1000 g for 10 min)
16 RBC INDICES Calculation from PCV, Hb, RBC Morphologic classification of anemias MCV (mean cell volume, fl) = PCV (l/l) 1000 / RBC (10 12 /l) MCH (mean cell hemoglobin, pg) = hemoglobin (g/l) / RBC (10 12 /l) MCHC (mean cell hemoglobin concentration, g/l) = hemoglobin (g/l) / PCV (l/l)
17 DIFFERENCIAL COUNT OF LEUKOCYTES (10 9 /l) Blood smear preparation Without anticoagulant directly from the syringe or needle immediately after collection Wedge smear technique (bevel edged slide!!) or Slide and coverglass technique
18 DIFFERENCIAL COUNT OF LEUKOCYTES (10 9 /l) Blood smear staining May-Grünwald/Giemsa-Romanowski stain, Wright-Giemsa stain fast staining methods, Diff-Quick, Hemacolor
19 DIFFERENCIAL COUNT OF LEUKOCYTES Recomended order for the evaluation of the blood smear: Differentiation of at least 100 leukocytes in meandering search for leukocytes from the central to the last third of the blood film (monolayer) expressing each type by a percentage (%) in relative percentage (l/l) calculation each type of absolute numbers
20 POSTANALYTIC PHASE This phase is based on appropriate interpretation of obtained results (in relation to reference values, other laboratory parameters, clinical findings) Intrinsic and external factors affecting the hemogram (age, sex, ambient environmental and season, captive versus wild birds, contamination of blood samples with lymph)
21 PACKED CELL VOLUME INTERPRETATION OF RESULTS PCV = g/l Ht < 0.32 anemia Ht > 0.58 dehydratation, erythrocytosis (polycytemia)
22 HEMOGLOBIN, MCV, MCH, MCHC INTERPRRETATION OF RESULTS Hb = g/l MCV = fl MCH = pg MCHC = g/l
23 ERYTROCYTES INTERPRETATION OF RESULTS Ery = 2,00 4, /l Polychromatophilic Ery = 1 5 % (normal) Birds with anemia Polychromatophilic ERY 5 % moderate regenerative response Polychromatophilic ERY 10 % marked regenerative response
24
25
26 MORPHOLOGIC CLASSIFICATION OF ANEMIAS RBC INDICES MCH normal MCH decreased MCV normal normocytic normocytic normochrome hypochrome MCV increased macrocytic macrocytic normochrome hypochrome MCV decreased microcytic microcytic normochrome hypochrome
27 ANEMIA Hemorrhagic anemia blood loss (traumatic injury, blood-sucking parasites, coagulopathies, hemorrhagic lesion of internal organs) Hemolytic anemia increased red cell destruction Depression anemia decreased red cell production (bone marrow damage)
28
29 HEMORRHAGIC ANEMIA The most common causes of this type of anemia include: traumatic injury blood-sucking parasites (ticks,mites,coccidia) coagulopathies (aflatoxicosis, coumarin poisoning, severe liver disease such as papovavirus) hemorrhagic lesion of internal organs (ulcerated neoplasm, gastric ulceration, rupture of the liver or spleen)
30 HEMOLYTIC ANEMIA This type of anemia can result from: parasitemias (blood parasites) bacterial septicemia (salmonelosis, spirochetosis) toxicosis (aflatoxins, certain plant chemicals-i.e. mustards, petroleum products)
31 DEPRESSION ANEMIA The most common causes of this type of anemia include: tuberculosis, chlamydiosis, aspergilosis chronic hepatopaties chronic nefropaties iron-deficiency, deficiency of vit. B 12 neoplasia
32 LEUKOCYTES Interpretation of results Leu = 3,50 15, /l Leukocytosis > 15, /l Leukopenia < 3, /l
33
34 HETEROPHILIA stress (corticosteroid-induced leukocytosis) bacterial infections, pox and herpesvirus infections, parasitic infections, fungal infections inflamations, i.e. egg yolk peritonitis lead/smoke intoxication hemorrhages, hemolysis
35 HETEROPENIA Bacterial and viral infections with bone marrow depression Inflammation with marked tissue necrosis Neoplasia leukemia, lymphosarcoma
36 LYMPHOCYTOSIS Chronic infections bacterial, viral, fungal, parasitic Lymphoid neoplasia lymphosarcoma, lymphatic leukemia
37 LYMPHOPENIA Acute stress Acute general infections Immunosuppression corticosteroids, radiation
38 MONOCYTOSIS Chronic granulomatous inflammation Chronic infections mykobacteriosis, chlamydiosis, aspergilosis Zinc deficiency
39
40 EOZINOPHILIA internal and external parasitism hypersensitive response type IV
41
42
43
44 BAZOPHILS The function of the avian basophile is not fully known. Avian basophils produce, store, and release histamin, so they may function in immediate hypersensitivity reactions, release mediators for thrombocyte activation, cause smooth muscle contractions, initiate edema, affect coagulation
45
46 THROMBOCYTES Interpretation of results /l thrombocytes / 1000 Ery (evaluation of blood smears)
47
48 THROMBOCYTOSIS Thrombocytosis associated with large thrombocytes has been reported in birds with chronic inflammation, which may be related to the thrombocytes phagocytic role in inflammatory disease
49 THROMBOCYTOPENIA Thrombocytopenia is usually the result of decreased bone marrow production or excessive peripheral utilization or destruction, and may be associated with severe septicemia and possibly diffuse intravascular coagulation (DIC)
The Complete Blood Count
The Complete Blood Count (Cartesian Thinking at Its Best) A SEM Image of Normal Human Blood Laurie Larsson February 22, 2010 Anatomy and Philology II Dr. Danil Hammoudi Introduction A complete blood count
More informationProf. Mahmoud Rushdi Faculty of Veterinary Medicine Assiut University Egypt. RBCs counts. Anaemia.
By Prof. Mahmoud Rushdi Faculty of Veterinary Medicine Assiut University Egypt ١ RBCs counts Normal Anaemia Polycythaemia Morphological Etiological Relative Absolute Size Stain Shape Inclusion Hemorrhagic
More information20/01/1439. Prof. M. Rushdi. Prof. Mahmoud Rushdi Faculty of Veterinary Medicine Assiut University Egypt.
By Prof. Mahmoud Rushdi Faculty of Veterinary Medicine Assiut University Egypt 1 CBC in Dog 2 1 Evaluation of the red blood cells (RBCs) Erythrocytes picture Determination of RBCs count (/mm 3 or T/l)
More informationHematology 101. Cindy Rogers, MT(ASCP) Diagnostics System Specialist
Hematology 101 Cindy Rogers, MT(ASCP) Diagnostics System Specialist More Acronyms...» CBC» RBC» HGB» HCT» WBC» MPV» PLT» RDW» DIFF» H&H» Complete Blood Count» Red Blood Cell» Hemoglobin» Hematocrit» White
More informationCollect and label sample according to standard protocols. Gently invert tube 8-10 times immediately after draw. DO NOT SHAKE. Do not centrifuge.
Complete Blood Count CPT Code: CBC with Differential: 85025 CBC without Differential: 85027 Order Code: CBC with Differential: C915 Includes: White blood cell, Red blood cell, Hematocrit, Hemoglobin, MCV,
More informationHEAMATOLOGICAL INDICES AND BONE MARROW BIOPSY
HEAMATOLOGICAL INDICES AND BONE MARROW BIOPSY HEMATOCRIT Hematocrit is a measure of the percentage of the total blood volume that is made up by the red blood cells The hematocrit can be determined directly
More informationASSESSMENT OF AVIAN ANAEMIA
Vet Times The website for the veterinary profession https://www.vettimes.co.uk ASSESSMENT OF AVIAN ANAEMIA Author : KATE ENGLISH Categories : Vets Date : July 21, 2008 KATE ENGLISH discusses how anaemia
More informationComplete Blood Count (CBC)
Complete Blood Count (CBC) Objectives 1. To estimate the number of RBC in blood sample 2. To estimate the number of total WBC in blood sample 3. To perform a differential count for a blood sample Introduction
More informationBLOOD. Dr. Vedat Evren
BLOOD Dr. Vedat Evren Blood Liquid suspension of formed elements Blood = Blood cells + plasma Plasma = Coagulation factors + serum Cells = Erythrocytes + Leukocytes + Thrombocytes 8 % of the total body
More informationRequirements: Glass slides Leishman stain Microscopes Disposable needles Vials containing anticoagulants Methylated-spirit Staining rack
Aim: To make a blood smear and to count the different types of leucocytes present in a stained blood smear and express their relative counts in percentage Principle - The blood contains various types of
More informationPreferred Clinical Services for Leading Age Florida August 26-27, 2015
DIAGNOSIS CODING ESSENTIALS FOR LONG-TERM CARE: CHAPTER 3, D CODES DISEASES OF THE BLOOD AND BLOOD-FORMING ORGANS AND CERTAIN DISORDERS INVOLVING THE IMMUNE MECHANISM Preferred Clinical Services for Leading
More informationThe Power of Peripheral Blood Smears: Apparent Diagnostic Clues (Part 1) (Wednesday, October 19, 2011)
The Power of Peripheral Blood Smears: Apparent Diagnostic Clues (Part 1) (Wednesday, October 19, 2011) By Gene Gulati, Ph.D., SH(ASCP) Conflict of Interest None Plan for the Course Review blood smears,
More informationHEMATOLOGY. Terry W. Campbell
CHAPTER 9 E valuation of the avian hemogram involves counting the various blood cells per microliter of blood as well as cytologic evaluation of the cells. The techniques involved in the evaluation of
More informationRed cell disorder. Dr. Ahmed Hasan
Red cell disorder Dr. Ahmed Hasan Things to be learned in this lecture Definition and clinical feature of anemia. Classification of anemia. Know some details of microcytic anemia Question of the lecture:
More informationTHE KENYA POLYTECHNIC UNIVERSITY COLLEGE
THE KENYA POLYTECHNIC UNIVERSITY COLLEGE SCHOOL OF HEALTH SCIENCES AND TECHNOLOGY DEPARTMENT OF BIOMEDICAL LABORATORY SCIENCES AND TECHNOLOGY DIPLOMA IN MEDICAL LABORATORY SCIENCE END OF YEAR 1 EXAMINATION
More informationHAEMATOLOGICAL EVALUATION OF ANEMIA. Sitalakshmi S Professor and Head Department of Clinical Pathology St John s medical College, Bangalore
HAEMATOLOGICAL EVALUATION OF ANEMIA Sitalakshmi S Professor and Head Department of Clinical Pathology St John s medical College, Bangalore Learning Objectives Laboratory tests for the evaluation of anemia
More informationRED BLOOD CELLS IMPORTANCE OF FILM EXAMINATION: PART ONE
Vet Times The website for the veterinary profession https://www.vettimes.co.uk RED BLOOD CELLS IMPORTANCE OF FILM EXAMINATION: PART ONE Author : Mark Richer Categories : Vets Date : March 25, 2013 Mark
More informationDetermination of hemoglobin concentration of blood
EXPERIMENT II Determination of hemoglobin concentration in blood RBC, WBC & platelet counts Determination of MCV, MCH, MCHC Determination of HCT/PCV Hemolysis & fragility test of RBC Dr. LL Wang Email:
More informationClinical implications for decreased lymphocytes (lymphopenia) o Corticosteroid therapy, adrenocortical hyperfunction, stress, shock
Learning Objectives At the completion of this program, the participants will be able to: 1. Identify the components of the CBC and Differential and their clinical implications. 2. Identify normal pediatric
More informationBlood Lecture Test Questions Set 2 Summer 2012
Blood Lecture Test Questions Set 2 Summer 2012 1. Leukocytes are attracted to a site of injury or disease by: a. diapedesis b. chemotaxis c. leukocytosis d. heparin e. leukomotosis 2. Leukocytes leave
More informationEvaluation of Anemia. Md. Shafiqul Bari Associate professor (Medicine) SOMC
Evaluation of Anemia Md. Shafiqul Bari Associate professor (Medicine) SOMC Definition Anemia is operationally defined as a reduction in one or more of the major RBC measurements Hemoglobin concentration
More informationTHE CLASSIFICATION OF ANEMIA*
THE CLASSIFICATION OF ANEMIA* RUSSELL L. HADEN, M.D. SUMMARY A laboratory and clinical classification of anemia has been outlined. The results of the blood study have been correlated with the clinical
More informationThe LaboratoryMatters
Laboratory Medicine Newsletter for clinicians, pathologists & clinical laboratory technologists. A Initiative. Complete Blood Count This issue highlights: CBC, while ubiquitous, is an excellent diagnostic
More informationDiseases Of The Blood
Diseases Of The Blood DR. Associate Professor Of Pathology Faculty Of Medicine Ain Shams University Red Blood Cells and Anemia RBC=4-6 million/mm 2 Hb=12-18 g/dl Oxygen Carrying Molecule Hemoglobin Tetramer:
More informationA CASE ORIENTED APPROACH Alan H. Rebar, DVM, PhD, DACVP
RED CELL RESPONSES IN DISEASE: A CASE ORIENTED APPROACH Alan H. Rebar, DVM, PhD, DACVP CLINICAL PATHOLOGY Introduction Anemia is one of the most common disease syndromes in domestic animals and may be
More informationContinuing Education Questions
FOCUS: INTERPRETING THE COMPLETE BLOOD COUNT Continuing Education Questions SUMMER 2017 1. A methodical approach to CBC interpretation that is aimed at medical laboratory professionals differs from one
More informationApproach to the child with anemia. Nittaya Wisanuyothin,MD. Pediatrics Department, Maharat Nakhonratchasima Hospital
Approach to the child with anemia Nittaya Wisanuyothin,MD. Pediatrics Department, Maharat Nakhonratchasima Hospital Definition of anemia Hb< 2 SD or P2.5 below the mean for a healthy of the same gender
More informationWhole Blood. Lab 29A. Blood. Plasma. Whole Blood. Formed Elements. Plasma: Fluid component. Formed elements: Cells and fragments
Whole Blood Lab 29A. Blood Plasma: Fluid component Water (90%) Dissolved plasma proteins Other solutes Formed elements: Cells and fragments RBCs (carry Oxygen) WBCs (immunity) Platelets (cell fragments
More informationInterpreting the CBC. Robert Miller PA Assistant Professor of Clinical Pediatrics and Family Medicine USC Keck School of Medicine Retired
Interpreting the CBC Robert Miller PA Assistant Professor of Clinical Pediatrics and Family Medicine USC Keck School of Medicine Retired The CBC 3 Cell Lines RBCs WBCs Platelets Assess general health Make
More informationCOMPANY OR UNIVERSITY
CONTRIBUTOR NAME Daniel Heinrich, DVM CONTRIBUTOR EMAIL dheinric@umn.edu COAUTHORS Jed Overmann, DVM, DACVP; Davis Seelig DVM, PhD, DACVP & Matthew Sturos, DVM COMPANY OR UNIVERSITY University of Minnesota
More informationGuide to the 1-3 Minute Blood Film Microscopic Review: Why and How?
Guide to the 1-3 Minute Blood Film Microscopic Review: Why and How? Dennis B. DeNicola, DVM, PhD, DACVP Chief Veterinary Educator IDEXX Laboratories, Inc. Westbrook, ME USA Adjunct Professor of Veterinary
More informationHematology Unit Lab 1 Review Material
Hematology Unit Lab 1 Review Material - 2018 Objectives Laboratory instructors: 1. Assist students during lab session Students: 1. Review the introductory material 2. Study the case histories provided
More informationClassifications of Anemia (table 2.2)
Classifications of Anemia (table 2.2) Anemia is a general name given to a group of circulating RBC deficiencies, both qualitativeand quantitative. Anemia can be caused by decreased RBC production, excess
More informationDifferential Blood Smear H3
Verein für Association pour le Associazione per il medizinische Qualitätskontrolle contrôle de qualité médical controllo di qualità medico Report Differential Blood Smear H3 MQ 2015-4 MQ, Institut für
More informationMicrocytic Hypochromic Anemia An Approach to Diagnosis
Microcytic Hypochromic Anemia An Approach to Diagnosis Decreased hemoglobin synthesis gives rise to microcytic hypochromic anemias. Hypochromic anemias are characterized by normal cellular proliferation
More informationComplete Blood Count (CBC) Assist.Prof. Filiz BAKAR ATEŞ
Complete Blood Count (CBC) Assist.Prof. Filiz BAKAR ATEŞ The complete blood count (CBC) is one of the most common blood test used. It analyzes the three major types of cells in blood 1. red blood cells,
More informationBlood & Blood Formation
Module IB Blood & Blood Formation Histology and Embryology Martin Špaček, MD (m.spacek@centrum.cz) http://www.lf3.cuni.cz/histologie Approximately 7% of a person's weight is blood (about 5 L) Blood consists
More informationLAB TIME/DATE. 1. most numerous leukocyte. 3. also called an erythrocyte; anucleate formed element. 6. ancestral cell of platelets
ighapmlre29apg245_250 5/12/04 2:46 PM Page 245 impos03 302:bjighapmL:ighapmLrevshts:layouts: NAME Blood LAB TIME/DATE REVIEW SHEET exercise 29A Composition of Blood 1. What is the blood volume of an average-size
More informationCLINICAL PATHOLOGY (PATH-404) CLASS LECTURES FOR. MID TERM Examination (PART I) For Free Downloading
CLINICAL PATHOLOGY (PATH-404) CLASS LECTURES FOR MID TERM Examination (PART I) For Free Downloading www.dvmdocs.webs.com Delivered by: DR. FARZANA RIZWI Department of Veterinary Pathology Faculty of Veterinary
More informationComplete Blood Count PSI AP Biology
Complete Blood Count PSI AP Biology Name: Objective Students will examine how the immunological response affects molecules in the blood. Students will analyze three complete blood counts and create diagnoses
More informationBlood DLC, Retic count, PCV, Hb and ESR. Dr. Tamara Alqudah
Blood DLC, Retic count, PCV, Hb and ESR Dr. Tamara Alqudah Differential Leukocyte Count (DLC) There are 5 main types of WBCs: 1. Neutrophils: 40-80% 2. Eosinophils: 1-6 % 3. Basophils: < 1-2% 4. Lymphocytes:
More informationANEMIA: WHAT IS THE CBC TELLING ME?
ANEMIA: WHAT IS THE CBC TELLING ME? C. Guillermo Couto, DVM, dipl. ACVIM Couto Veterinary Consultants, Hilliard, OH coutovetconsultants@gmail.com Adapted from Nelson and Couto Small Animal Internal Medicine,
More informationChapter 13 The Blood
Chapter 13 The Blood Copyright 2015 Wolters Kluwer Health Lippincott Williams & Wilkins Overview Key Terms agglutination erythrocyte lymphocyte albumin fibrin megakaryocyte anemia hematocrit monocyte antigen
More informationTaking The Fear Out of Abnormal CBC s Problems of Production, Destruction or loss
Taking The Fear Out of Abnormal CBC s Problems of Production, Destruction or loss Joanne Eddington, MN, FNP, AOCN Providence Oncology and Hematology Care Clinic - Eastside Blood Cell Abnormalities Abnormalities
More information8.2 Principles of Quantitative Hematologic Determinations (1)
3 8. FIELD CENTER HEMATOLOGY SERVICES 8.1 Clinical Significance Quantitation of the formed elements of the blood (erythrocytes -RBCs, leukocytes - WBCs, and platelets) is important in the ARIC study primarily
More informationPractice 4 Hemal biology. Department of parasitology, AHUM
Practice 4 Hemal biology Department of parasitology, AHUM Definition Hemal biology:study of normal and pathologic aspects of blood Contents 1. blood components 2. hematopoiesis 3. blood function 4. white
More informationYear 2003 Paper two: Questions supplied by Tricia
QUESTION 65 A 36-year-old man presents in a post-ictal state after an observed generalised seizure. Full blood investigation shows: haemoglobin 0 g/l [128-175] mean corpuscular volume (MCV) 106 fl [80-7]
More informationFull Blood Count analysis Is a 3 part-diff good enough? Dr Marion Münster, Sysmex South Africa
Full Blood Count analysis Is a 3 part-diff good enough? Dr Marion Münster, Sysmex South Africa The Role of the FBC in clinical decision making History Examination Investigations Decision 70% FBC Laboratory
More informationBio& 242 Unit 3 / Lecture 1
Bio& 242 Unit 3 / Lecture 1 Major Functions of Blood The body contains 4 to 6 liters of blood with an average ph of 7.35 to 7.45. Functions include: Transport Oxygen, Carbon Dioxide, Nutrients, Hormones,
More informationIncorporating Differentials Into Every Complete Blood Count. Paige Flowers, LVT Dogwood Veterinary Internal Medicine
Incorporating Differentials Into Every Complete Blood Count Paige Flowers, LVT Dogwood Veterinary Internal Medicine Complete Blood Count Diagnostic performed to evaluate the quantity and morphology of
More informationHematologic changes in systemic diseases. Chittima Sirijerachai
Hematologic changes in systemic diseases Chittima Sirijerachai Systemic diseases Infection Renal diseases Liver diseases Connective tissue diseases Malignancy Anemia of chronic disease (ACD) Chronic infections:
More informationTHE UNIVERSITY OF JORDAN FACULTY OF MEDICINE DEPARTMENT OF PATHOLOGY
THE UNIVERSITY OF JORDAN FACULTY OF MEDICINE DEPARTMENT OF PATHOLOGY INTRODUCTION TO ANEMIA Third year medical students First semester 2018/2019 Dr. RBC DISORDERS Lecturer: Dr. Tariq Al-Adaily Email: TNALADILY@ju.edu.jo
More informationPeripheral Blood Smear Examination. Momtazmanesh MD. Ped. Hematologist & Oncologist Loghman General Hospital
1395 Peripheral Blood Smear Examination Momtazmanesh MD. Ped. Hematologist & Oncologist Loghman General Hospital Peripheral Blood Smear A peripheral blood smear is a snapshot of the cells that are present
More informationExperiences in avian clinical pathology
Experiences in avian clinical pathology Sue Jaensch. IDEXX Laboratories Sydney Introduction 140 avian biochemistry and/or haematology submissions to the Sydney IDEXX laboratory were analysed in regard
More informationChapter 11. Lecture and Animation Outline
Chapter 11 Lecture and Animation Outline To run the animations you must be in Slideshow View. Use the buttons on the animation to play, pause, and turn audio/text on or off. Please Note: Once you have
More informationChapter 3 Diseases of the Blood and Bloodforming Organs and Certain Disorders Involving the Immune Mechanism D50-D89
Chapter 3 Diseases of the Blood and Bloodforming Organs and Certain Disorders Involving the Immune Mechanism D50-D89 Presented by Jennifer Kurkulonis 1 FOUR MAJOR TYPES OF BLOOD CELLS White blood cells
More informationHLS Midterm ( )
HLS Midterm (2012-2013) 1. Which of the following cells increase in level during allergic reactions? (a) Neutrophils (b) Basophils (c) Eosinophils (d) Lymphocytes (e) Monocytes 2. Which of the following
More informationProceeding of the LAVC Latin American Veterinary Conference Oct , 2009 Lima, Peru
Close this window to return to IVIS www.ivis.org Proceeding of the LAVC Latin American Veterinary Conference Oct. 16-19, 2009 Lima, Peru Reprinted in the IVIS website with the permission of the LAVC http://www.ivis.org/
More informationDifferential Blood Smear H3
Verein für Association pour le Associazione per il medizinische Qualitätskontrolle contrôle de qualité médical controllo di qualità medico Report Differential Blood Smear H3 MQ 2018-1 MQ, Institut für
More informationDeconstructing the CBC
Deconstructing the CBC Dr. Ann M. Wexler Solano Hematology Oncology September 10, 2017 What Are the Major Components of Blood? Red Blood Cells (also called erythrocytes) White Blood Cells (also called
More informationYear(Semester) At a Glance HST II Clinical Laboratory Science Semester Course
Year(Semester) At a Glance HST II Clinical Science Semester Course Three Weeks 1 st 3 weeks 2 nd 3 weeks 3 rd 3 weeks 4 th 3 weeks 5 th 3 weeks 6 th 3 weeks Topics/ Concepts Resource: Our Book Safety OSHA
More informationA. Blood is considered connective tissue. RBC. A. Blood volume and composition 1. Volume varies - average adult has 5 liters
A. Blood is considered connective tissue. RBC A. Blood volume and composition 1. Volume varies - average adult has 5 liters 2. 45% cells by volume called hematocrit (HCT) a. red blood cells (RBC) mostly
More informationPNH Glossary of Terms
AA Absolute neutrophil count Alendronate Allergen ALT Anemia Antibodies Anticoagulant Anticoagulation Antigen Antithymocyte globulin (ATG) Aplastic Aplastic anemia Band Bilirubin Blast cells Bone marrow
More informationPCCN Review Hematology
PCCN Review Hematology Leanna R. Miller, RN, MN, CCRN-CMC, PCCN-CSC CEN, CNRN, CMSRN, NP Education Specialist LRM Consulting Nashville, TN Anemia Definition reduction in RBC concentration Causes iron deficiency
More informationHematology 101. Blanche P Alter, MD, MPH, FAAP Clinical Genetics Branch Division of Cancer Epidemiology and Genetics Bethesda, MD
Hematology 101 Blanche P Alter, MD, MPH, FAAP Clinical Genetics Branch Division of Cancer Epidemiology and Genetics Bethesda, MD Hematocrits Plasma White cells Red cells Normal, Hemorrhage, IDA, Leukemia,
More informationHematology. The Study of blood
Hematology The Study of blood Average adult = 8-10 pints of blood Composition: PLASMA liquid portion of blood without cellular components Serum plasma after a blood clot is formed Cellular elements are
More informationTECHNICAL UNIVERSITY OF MOMBASA
TECHNICAL UNIVERSITY OF MOMBASA Faculty of Applied and Health Sciences DEPARTMENT OF MEDICAL SCIENCES DIPLOMA IN MEDICAL LABORATORY SCIENCES (DMLS ) AML 2301 : HAEMATOLOGY II SPECIAL/SUPPLEMENTARY : EXAMINATIONS
More informationChapter 14. Blood. Blood Volume. Blood Composition. Blood
Blood connective tissue transports vital substances maintains stability of interstitial fluid distributes heat Chapter 14 Blood Blood Cells form mostly in red bone marrow red blood cells white blood cells
More informationHemolysis and Pre-analytical Variables. Kathleen Finnegan, MS MT(ASCP)SH CM
Thursday April 6, 2017 C23 Hemolysis and Pre-analytical Variables Kathleen Finnegan, MS MT(ASCP)SH CM Clinical Associate Professor and Program Director of the Phlebotomy Training Program, Dept. of Clinical
More informationAverage adult = 8-10 pints of blood. Functions:
Average adult = 8-10 pints of blood Functions: Transports nutrients, oxygen, cellular waste products, and hormones Aids in distribution of heat Regulates acid-base balance Helps protect against infection
More informationBeyond the CBC Report: Extended Laboratory Testing in the Evaluation for Hematologic Neoplasia Disclosure
Beyond the CBC Report: Extended Laboratory Testing in the Evaluation for Hematologic Neoplasia Disclosure I am receiving an honorarium from Sysmex for today s presentation. 1 Determining the Etiology for
More informationLaboratory for diagnosis of THALASSEMIA
SCBM343 CLINICAL PATHOLOGY 2(1-2-3) Laboratory for diagnosis of THALASSEMIA PORNTHIP CHAICHOMPOO pornthip.chh@mahidol.ac.th Acknowledgements Dr. Pranee Winichagoon Fucharoen Ms. Pornnapa Khampan Thalassemia
More informationFactors affecting oxygen dissociation curve
P a g e 1 Factors affecting oxygen dissociation curve As you know, hemoglobin contains 4 heme molecules that bind 4 oxygen molecules (8 atoms). These 4 heme molecules, however, do not bind oxygen all at
More informationChanges of haematological parameters in common pheasant throughout the year
Veterinarni Medicina, 51, 2006 (1): 29 34 Original Paper Changes of haematological parameters in common pheasant throughout the year K. HAUPTMANOVA 1, M. MALY 2, I. LITERAK 1 1 Department of Biology and
More informationBONE MARROW PERIPHERAL BLOOD Erythrocyte
None Disclaimer Objectives Define anemia Classify anemia according to pathogenesis & clinical significance Understand Red cell indices Relate the red cell indices with type of anemia Interpret CBC to approach
More informationHEMATOLOGY. General information Whole blood in EDTA (purple top tube) is the required specimen for mammalian hematology.
VETERINARY DIAGNOSTIC SERVICES CLINICAL PATHOLOGY Updated: October 1, 2014 The Clinical Pathology Section of Veterinary Diagnostic Services provides testing in the fields of hematology, urinalysis, cytology,
More informationINTERELATIONSHIP BETWEEN IDA AND VITAMIN D DEFICIENCY IS NOW ESTABLISHED
INTERELATIONSHIP BETWEEN IDA AND VITAMIN D DEFICIENCY IS NOW ESTABLISHED Rationale for Combining Iron & Vit-D Vit D deficiency and Iron deficiency Anaemia the two most menacing disorders - are inter-related
More informationClinician Blood Panel Results
Page 1 of 7 Blood Panel - Markers Out of Range and Patterns (Pattern: proprietary formula using one or more Blood Markers) Blood Panel: Check for Markers that are out of Lab Range ***NOTE*** Only one supplement
More informationChapter 46. Care of the Patient with a Blood or Lymphatic Disorder
Chapter 46 Care of the Patient with a Blood or Lymphatic Disorder All items and derived items 2015, 2011, 2006 by Mosby, Inc., an imprint of Elsevier Inc. All rights reserved. Components of the Blood Red
More informationThe % of blood consisting of packed RBCs is known as the hematocrit. Blood s color ranges from scarlet (oxygen-rich) to dark red (oxygen poor).
Biology Blood Blood is a fluid connective tissue consisting of cells suspended in a liquid fibrous matrix. The cells are called formed elements and the liquid matrix is known as plasma. The formed elements
More informationDrop of Blood Unravels Mysteries. Prof. Salma Afrose Department of Hematology Dhaka Medical College
Drop of Blood Unravels Mysteries Prof. Salma Afrose Department of Hematology Dhaka Medical College Peripheral Blood Film (PBF) PBF is a laboratory workup that involves cytology of Peripheral blood cell
More informationHEMATOLOGY: BLOOD SMEAR REVIEW IN THE EMERGENCY SETTING
HEMATOLOGY: BLOOD SMEAR REVIEW IN THE EMERGENCY SETTING Deanna Schaefer, DVM, MS, MT(ASCP), Dipl ACVP Assistant Professor, Veterinary Clinical Pathology, University of Tennessee The main objective of this
More informationLifeblood Lab Activity
History of Blood: It is the universal symbol of horror, of death, yet it is the one thing that keeps you living. It is the blood that is coursing through your veins. But, what do you really know about
More informationAVCPT FORMULA GUIDE HEMATOLOGY. Test Formula Example Mean Corpuscular Volume (MCV) Mean Corpuscular Hemoglobin Concentration (MCHC)
AVCPT FMULA GUIDE HEMATOLOGY Test Formula Example Mean Corpuscular Volume (MCV) PCV x RBC = MCV (fl) Patient Information: RBC = 7.50 x 6 /µl 45 x 7.50 = 60.0 fl MCV = 60.0 fl Mean Corpuscular Hemoglobin
More informationInterpreting Blood Tests Part 1. Dr Andrew Smith
Interpreting Blood Tests Part 1 Dr Andrew Smith Outline Part 1 (This Week) Introduction Which Tube!?! FBCs U+Es Part 2 (Next Week): More Electrolytes LFTs Clotting Extras Introduction Bloods are a core
More information78 The Power of Peripheral Blood Smears-Apparent Diagnostic Clues (Part 1) Gene Gulati PhD, SH(ASCP)
78 The Power of Peripheral Blood Smears-Apparent Diagnostic Clues (Part 1) Gene Gulati PhD, SH(ASCP) 2011 Annual Meeting Las Vegas, NV AMERICAN SOCIETY FOR CLINICAL PATHOLOGY 33 W. Monroe, Ste. 1600 Chicago,
More informationChapter 19: Cardiovascular System: Blood
Chapter 19: Cardiovascular System: Blood I. Functions of Blood A. List and describe the seven major homeostatic functions of blood: 1. 2. 3. 4. 5. 6. 7. II. Plasma A. Composition 1. It is a fluid consisting
More informationIDEXX VetAutoread Hematology Analyzer Casebook
IDEXX VetAutoread Hematology Analyzer Casebook w Casebook An explanation of numerous analyzer reports as compiled by: Dr. Allan Hart (deceased) Laboratory Director New Haven Central Hospital for Veterinary
More informationProceedings of the World Small Animal Veterinary Association Mexico City, Mexico 2005
Close this window to return to IVIS Proceedings of the World Small Animal Veterinary Association Mexico City, Mexico 2005 Hosted by: Reprinted in the IVIS website with the permission of the WSAVA Laboratory
More informationGeneral Pathology Theory Syllabus for II B.D.S.
General Pathology Theory Syllabus for II B.D.S. Sr. No. Topic (Must Know) (Desirable to know) 1.Introduction to Pathology - Different sections in pathology - The Cell in health - Normal cell structure
More informationUse of the XE-2100 in a Patient with Cold Auto-immune Hemolytic Anemia
Use of the XE-21 in a Patient with Cold Auto-immune Hemolytic Anemia Gudrun STAMMINGER and Lothar BEIER Klinikum Chemnitz ggmbh, Institut für Laboratoriumsmedizin, Flemmingstraße 2, Chemnitz, Germany.
More informationAmerican University of Beirut Faculty of Health Sciences Medical Laboratory Sciences Program
P 1 of 5 American University of Beirut Faculty of Health Sciences Medical Laboratory Sciences Program MLSP 201 () Fall Semester 2017-2018 Name Rolla Al-Khatib Course Credits: 3 credits Office Hours: TWRF:
More informationThe Full Blood Count. Dave Reynders University of Pretoria Paediatric Oncology and Haematology
The Full Blood Count Dave Reynders University of Pretoria Paediatric Oncology and Haematology 1 History Empedocles in the 5 th century BC Vasculature contains Blood, Phlegm, Black bile and Yellow Bile.
More information3. Blood Cell Histograms:
LECTURE MODULE 6c: ELECTRONIC CELL COUNTING PART III 3. Blood Cell Histograms: a. The Coulter cell counters today provides size distributions of the cellular content: 1) volume given in µm 3 or fl vs relative
More information, Manu S nejana Dro. afe b,c. nca d, V. Ost
Annals of West University of Timisoara Series of Chemistry 20 (2) (2 011) 6575 HEMATOLOGICAL INDICES IN A POPULATION SAMPLE IN TIMIŞOARA,, ROMÂNIA Ramona Ru mel a b,c, Manu ela Mincea, Katalin K is b,
More informationDR SUDHIR MEHTA MD,MNAMS,FICP. Senior Professor & Head Medical Unit SMS Medical College & Hospital Jaipur
DR SUDHIR MEHTA MD,MNAMS,FICP Senior Professor & Head Medical Unit SMS Medical College & Hospital Jaipur s.smehta@hotmail.com CBC..What is the Utility of performing this basic Hematology Test? 10/31/2010
More informationDisorders of Blood Cells & Blood Coagulation
Disorders of Blood Cells & Blood Coagulation HIHIM 409 WBC count RBC count WBC differential Hemoglobin (HGB) Hematocrit (HCT) % of volume occupied by RBCs CBC Red cell indices Mean cell volume (MCV) average
More informationPseudobasophilia in Pediatric Age Group
Original Article DOI: 10.17354/ijss/2015/259 Pseudobasophilia in Pediatric Age Group Femela Muniraj 1, Vijay Amritraj 2 1 Assistant Professor, Department of Pathology, Chettinad Hospital & Research Institute,
More informationApproach to a pale child
Approach to a pale child Dr. Dafalla Ahmed Babiker Jazan university objectives Definition of anemia Classification and causes Important points in history and physical examination Investigations. Definition
More informationDiagnostic Approach to Patients with Anemia
J KMA Special Issue Diagnostic Approach to Patients with Anemia Seonyang Park, MD Department of Internal Medicine, Seoul National University College of Medicine E mail : seonpark@snu.ac.kr J Korean Med
More information