A Perf-ect Differential
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1 A Perf-ect Differential Carolyn Marcus, MD Disclosure of Financial Relationships Husband works as in-house legal counsel at Sanofi
2 Case Presentation 6 year old boy with a history of constipation presents with 24 hours of abdominal pain Pain is diffuse and colicky, has periods without pain Review of Systems 2 episodes of NBNB emesis Has been having daily soft small bowel movements, no diarrhea Tactile fevers, no documented fevers Decreased PO but no anorexia Sore throat No dysuria, rashes, testicular pain, respiratory symptoms
3 Earlier today Initial ED: KUB revealed a large stool burden Enema given which led to a bowel movement with pain relief, so discharged home with diagnosis of constipation Pain recurred in the ED parking lot, so sent to our ED PMH: constipation, seen by GI 2 months earlier PSH: none Meds: Miralax PRN Allergies: none Family: non-contributory Social: non-contributory
4 Differential Diagnosis Differential Diagnosis Most common/likely
5 Differential Diagnosis Must not miss Differential Diagnosis Fits with symptoms
6 Physical Exam T 37 HR 108 RR 20 BP 106/59 Differential Diagnosis
7 Differential Diagnosis Differential Diagnosis
8 Differential Diagnosis Workup
9 Differential Diagnosis Urinalysis: +ketones, negative blood Differential Diagnosis
10 Differential Diagnosis Moderate stool burden
11 Limited exam but no evidence of intussusception, appendix not visualized Differential Diagnosis
12 Differential Diagnosis Differential Diagnosis
13 Differential Diagnosis Admit for clean out
14 Hospital Course NG Golytely initiated, started having soft bowel movements Parents thought pain was possibly improving
15
16 Continued with Golytely Continued with Golytely
17 Hospital Day 2
18 Small questionably blind ending loop of bowel in midline pelvis which appears mildly thickened and associated with adjacent fat stranding and trace amount of free fluid
19 Small questionably blind ending loop of bowel in midline pelvis which appears mildly thickened and associated with adjacent fat stranding and trace amount of free fluid
20
21
22 A probable blind-ending tubular structure off the ileum demonstrating hyperenhancement and wall thickening in the periumbilical region, most consistent with A probable blind-ending tubular structure off the ileum demonstrating hyperenhancement and wall thickening in the periumbilical region, most consistent with Meckel s diverticulitis
23 Surgical Findings Final Diagnosis Meckel s diverticulum lined by gastric and small intestinal type Meckel s mucosa diverticulitis with a focal perforation of adjacent small with intestinal perforation wall with inflammation Meckel s Diverticulum When symptomatic Bleeding Abdominal pain Obstruction Inflammation/diverticulitis Perforation
24 Meckel s Diverticulitis Male-tofemale ratio of 2:1 Occurs in 2% of population Bleeding Meckel s lined by 2 different types of mucosa Located within 2 feet from ileocecal valve Can be 2 inches in length 2% with complication over course of their lives (typically before age 2)
25 Our Patient Post-operative ileus that slowly improved Small bowel obstruction secondary to adhesions requiring repeat surgery Now doing well 1 year later Cognitive Biases
26 Cognitive Biases 6 year old boy with a history of constipation (seen by GI 2 months prior) presents with 24 hours of abdominal pain Cognitive Biases 6 year old boy with a history of constipation (seen by GI 2 months prior) presents with 24 hours of abdominal pain
27 Cognitive Biases KUBs revealed moderate-large stool burden Pain relief with enema Lessons Learned
28 Differential Diagnosis Meckel s diverticulitis Differential Diagnosis Meckel s diverticulitis
29 References Abizeid GA, Aref H. Case report: preoperatively diagnosed perforated Meckel s diverticulum containing gastric and pancreatic-type mucosa. BMC Surg Apr 11; 17(1):36 Croskerry P. The importance of cognitive errors in diagnosis and strategies to minimize them. Acad Med Aug; 78(8): Javid P and Pauli EM. Meckel s diverticulum. In: UpToDate, Soybel DI and Heyman MB (Eds), UpToDate, Waltham, MA, 2016.
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