Spreading of Epidemic Based on Human and Animal Mobility Pattern

Size: px
Start display at page:

Download "Spreading of Epidemic Based on Human and Animal Mobility Pattern"

Transcription

1 Spreading of Epidemic Based on Human and Animal Mobility Pattern Yanqing Hu, Dan Luo, Xiaoke Xu, Zhangang Han, Zengru Di Department of Systems Science, Beijing Normal University

2 Background & Motivation In the recent 10 years, the worldwide deluges of epidemics happened in human societies have been more frequent, e. g., the SARS in 2003, the H5N1 in 2006 and H1N1 in 2009.

3 Pattern Levy flight Most of the studies on human and animal mobility pattern including experimental data and theoretic analysis found that their mobility pattern follows the Levy flight: 2 Pr( d ) d Scaling laws of marine predator search behaviour, Nature (2008 ) D. Brockmann, L. Hufnagel and T. Geisel, The scaling laws of human travel, Nature, 439, , (2006).

4 1. Epidemic spreading processes always follow the mobility of human and animal. 2. Network based epidemic model should reflect the feature of human and animal mobility. Previous works focus on the topology of network based epidemic models. 3. We want to establish a network model with a Levy flight spatial structure to reflect the feature of human and animal mobility pattern. 1. How to describe the Levy flight spatial structure of epidemic spreading? 2. Whether the exponential of the Levy flight on epidemic spreading process will show the same character as the mobility patterns?

5 How does the mobility pattern impact on epidemical diffusion? 1. SI model for extremely rapid spreading epidemic. 2. SIS model for investigating the diffusion ability.

6 Spatial Network Model and Property Energy To establish a Levy flight spatial network, as all the individuals only have limited energy, there must be a cost constraint on the mobility. Hence, we give a restriction on total energy. The frequency distribution of sum of walk distances in a day for deer and sheep. Both distribution are vary narrow, which represents the energy distribution is homogenous. Source: These data were obtained at the Macaulay Institute s Glensaugh Research Station, Aberdeenshire, in north-east Scotland.

7 Network model Based on a uniform cycle, each node denotes a small group of people. Given a restriction on Ω = total k nenergy, we get a onedimensional weighted network with a Levy flight spatial structure. α wij dij n wd ij i= 1, j= 1 ij = W w = ij Wd 2 ne( d) α ij n/2 d = 1 d α 1. Full connected weighted network and each node is same W w with the k = degree =. E(d) denotes the expectation of ne( d) E( d) one Levy flight distance. 2. Each node has limited energy. 3. The weight of edge means the expectation of communication times.

8 Diffusion On this weighted network, the infected probability is related with the weight. j I 1 (1 ) w ij A susceptive node i will be infected with a v probability, where v is the spreading ratio, and I is the set of infected nodes. Infected nodes become susceptive with rate. The effective spreading rate is defined as. 1. SI model Randomly choose one node as an infected individual, others are susceptible. δ v λ = δ Terminate until all the nodes are infected and register the steps have been taken as T.

9 Results of SI Model 1. Epidemic spreading speed with different exponent Epidemic spreading speed with different exponent on SI model. The curve has a lowest point when a 2 Which implies that the mobility pattern will driven the epidemic diffusion. n=1000 V=0.05

10 2. Spread ratio under different a and various network size n

11 3.Terminate time with population size under different α and various size n There is a log-log linear dependence between terminate time and the population size. When a=-2, the slope is 0.5

12 2. SIS model α 2 On SIS model, there is a phase transition when. Using the mean field theory, we analyzed the critical threshold of SIS model on this network. Reaction diffusion equation : ρ() t = ρ() t + λ< k> ρ()[1 t ρ()] t t Our Model: The reaction equation of SIS model w ρ E( d) [1 (1 ) ](1 ) dρ = ρ + λ ρ dt 1 α 2 λc = 1 Ed ( ) Z( α) = α > 2 k c cz( α 1) 1 λ c = < k >

13 There is a phase transition α 2when, this conclusion can be extended to the cases of high-dimensional. The simulated and analytical critical threshold with different exponent on SIS model. w=10

14 The End, Thanks!

Stochastic Modelling of the Spatial Spread of Influenza in Germany

Stochastic Modelling of the Spatial Spread of Influenza in Germany Stochastic ling of the Spatial Spread of Influenza in Germany, Leonhard Held Department of Statistics Ludwig-Maximilians-University Munich Financial support by the German Research Foundation (DFG), SFB

More information

Density dependent diffusion and spread of epidemics in a metapopulation model.

Density dependent diffusion and spread of epidemics in a metapopulation model. Erice (Italy) August 30 2015 September 5 2015. Density dependent diffusion and spread of epidemics in a metapopulation model. Marta Pellicer UNIVERSITAT DE GIRONA Catalunya (Spain) Joint work with A. Avinyó,

More information

Epidemics & Networks. Jesús Gómez Gardeñes Instituto de Biocomputación y Física de Sistemas Complejos (BIFI) Universidad de Zaragoza

Epidemics & Networks. Jesús Gómez Gardeñes Instituto de Biocomputación y Física de Sistemas Complejos (BIFI) Universidad de Zaragoza Epidemics & Networks Jesús Gómez Gardeñes Instituto de Biocomputación y Física de Sistemas Complejos (BIFI) Universidad de Zaragoza DO WE NEED A MOTIVATION? Epidemics Lecture III: & Networks, Walks, Conges4on

More information

MMCS Turkey Flu Pandemic Project

MMCS Turkey Flu Pandemic Project MMCS Turkey Flu Pandemic Project This is a group project with 2 people per group. You can chose your own partner subject to the constraint that you must not work with the same person as in the banking

More information

An epidemic spreading model based on community structure in dual social networks

An epidemic spreading model based on community structure in dual social networks International Journal of Microbiology and Mycology IJMM pissn: 2309-4796 http://www.innspub.net Vol. 5, No. 3, p. 1-10, 2017 Open Access RESEARCH PAPER An epidemic spreading model based on community structure

More information

Agent-Based Models. Maksudul Alam, Wei Wang

Agent-Based Models. Maksudul Alam, Wei Wang Agent-Based Models Maksudul Alam, Wei Wang Outline Literature Review about Agent-Based model Modeling disease outbreaks in realistic urban social Networks EpiSimdemics: an Efficient Algorithm for Simulating

More information

Network Science: Principles and Applications

Network Science: Principles and Applications Network Science: Principles and Applications CS 695 - Fall 2016 Amarda Shehu,Fei Li [amarda, lifei](at)gmu.edu Department of Computer Science George Mason University Spreading Phenomena: Epidemic Modeling

More information

Impact of Clustering on Epidemics in Random Networks

Impact of Clustering on Epidemics in Random Networks Impact of Clustering on Epidemics in Random Networks Joint work with Marc Lelarge TREC 20 December 2011 Coupechoux - Lelarge (TREC) Epidemics in Random Networks 20 December 2011 1 / 22 Outline 1 Introduction

More information

Modeling of epidemic spreading with white Gaussian noise

Modeling of epidemic spreading with white Gaussian noise Article Statistical Physics and Mathematics for Complex Systems December 20 Vol.56 No.34: 3683 3688 doi: 0.007/s434-0-4753-z SPECIAL TOPICS: Modeling of epidemic spreading with white Gaussian noise GU

More information

Infectious disease modeling

Infectious disease modeling Infectious disease modeling Matthew Macauley Department of Mathematical Sciences Clemson University http://www.math.clemson.edu/~macaule/ Math 4500, Spring 2017 M. Macauley (Clemson) Infectious disease

More information

How Viruses Spread Among Computers and People

How Viruses Spread Among Computers and People Institution: COLUMBIA UNIVERSITY Sign In as Individual FAQ Access Rights Join AAAS Summary of this Article debates: Submit a response to this article Download to Citation Manager Alert me when: new articles

More information

Large Graph Mining: Power Tools and a Practitioner s guide

Large Graph Mining: Power Tools and a Practitioner s guide Large Graph Mining: Power Tools and a Practitioner s guide Task 6: Virus/Influence Propagation Faloutsos, Miller,Tsourakakis CMU KDD'09 Faloutsos, Miller, Tsourakakis P6-1 Outline Introduction Motivation

More information

Modelling global epidemics: theory and simulations

Modelling global epidemics: theory and simulations Modelling global epidemics: theory and simulations Marc Barthélemy CEA, IPhT, France marc.barthelemy@cea.fr Manchester meeting Modelling complex systems (21-23 june 2010) Outline Introduction Metapopulation

More information

Mathematical Formulation and Numerical Simulation of Bird Flu Infection Process within a Poultry Farm

Mathematical Formulation and Numerical Simulation of Bird Flu Infection Process within a Poultry Farm Mathematical Formulation and Numerical Simulation of Bird Flu Infection Process within a Poultry Farm Arrival Rince Putri, Tertia Delia Nova and M. Watanabe, Graduate School Environmental and Life Science,

More information

The Impact of Demographic Variables on Disease Spread: Influenza in Remote Communities

The Impact of Demographic Variables on Disease Spread: Influenza in Remote Communities esupplementary Information The Impact of Demographic Variables on Disease Spread: Influenza in Remote Communities Marek Laskowski, Luiz C. Mostaço-Guidolin, Amy Greer, Jianhong Wu, Seyed M. Moghadas This

More information

Strategies for containing an emerging influenza pandemic in South East Asia 1

Strategies for containing an emerging influenza pandemic in South East Asia 1 Strategies for containing an emerging influenza pandemic in South East Asia 1 Modeling pandemic spread and possible control plans of avian flu H5N1 BBSI, Nicole Kennerly, Shlomo Ta asan 1 Nature. 2005

More information

SEIQR-Network Model with Community Structure

SEIQR-Network Model with Community Structure SEIQR-Network Model with Community Structure S. ORANKITJAROEN, W. JUMPEN P. BOONKRONG, B. WIWATANAPATAPHEE Mahidol University Department of Mathematics, Faculty of Science Centre of Excellence in Mathematics

More information

MAE 298, Lecture 10 May 4, Percolation and Epidemiology on Networks

MAE 298, Lecture 10 May 4, Percolation and Epidemiology on Networks MAE 298, Lecture 10 May 4, 2006 Percolation and Epidemiology on Networks Processes on networks Search for information Spreading processes Interplay of topology and function Epidemiology Understanding how

More information

Module 5: Introduction to Stochastic Epidemic Models with Inference

Module 5: Introduction to Stochastic Epidemic Models with Inference Module 5: Introduction to Stochastic Epidemic Models with Inference Instructors:, Dept. Mathematics, Stockholm University Ira Longini, Dept. Biostatistics, University of Florida Jonathan Sugimoto, Vaccine

More information

SIS-SEIQR Adaptive Network Model for Pandemic Influenza

SIS-SEIQR Adaptive Network Model for Pandemic Influenza SIS-SEIQR Adaptive Network Model for Pandemic Influenza WANNIKA JUMPEN,2, SOMSAK ORANKITJAROEN,2, PICHIT BOONKRONG,2 BOONMEE WATTANANON, BENCHAWAN WIWATANAPATAPHEE,2 Department of Mathematics, Faculty

More information

and Internet Computing Amin Saberi Stanford University

and Internet Computing Amin Saberi Stanford University Epidemics Algorithmic on Social Game Networks Theory and Internet Computing Amin Saberi Stanford University Social Networks as Graphs Nodes: individuals, webpages (blogs), profiles, PC s Edges: friendship,

More information

Containment Policies for Transmissible Diseases

Containment Policies for Transmissible Diseases Containment Policies for Transmissible Diseases Shirish Tatikonda, Sameep Mehta, and Srinivasan Parthasarathy Department of Computer Science and Engineering, The Ohio State University, Columbus, OH 43210,

More information

Module 5: Introduction to Stochastic Epidemic Models with Inference

Module 5: Introduction to Stochastic Epidemic Models with Inference Module 5: Introduction to Stochastic Epidemic Models with Inference Instructors: Tom Britton, Dept. Mathematics, Stockholm University Ira Longini, Dept. Biostatistics, University of Florida Jonathan Sugimoto,

More information

= Λ μs βs I N, (1) (μ + d + r)i, (2)

= Λ μs βs I N, (1) (μ + d + r)i, (2) Advanced Studies in Biology, Vol., 29, no. 8, 383-39 Mathematical Model of the Influenza A(HN) Infection K. Hattaf and N. Yousfi 2 Laboratory Analysis, Modeling and Simulation Department of Mathematics

More information

Generation times in epidemic models

Generation times in epidemic models Generation times in epidemic models Gianpaolo Scalia Tomba Dept Mathematics, Univ of Rome "Tor Vergata", Italy in collaboration with Åke Svensson, Dept Mathematics, Stockholm University, Sweden Tommi Asikainen

More information

Information and Communication Technologies EPIWORK. Developing the Framework for an Epidemic Forecast Infrastructure.

Information and Communication Technologies EPIWORK. Developing the Framework for an Epidemic Forecast Infrastructure. Information and Communication Technologies EPIWORK Developing the Framework for an Epidemic Forecast Infrastructure http://www.epiwork.eu Project no. 231807 D1.1 Analysis of Epidemic Dynamics on Clustered

More information

Strategies for Crowdsourcing for Disaster Situation Information

Strategies for Crowdsourcing for Disaster Situation Information Strategies for Crowdsourcing for Disaster Situation Information E. T.-H. Chu 1, Y.-L. Chen 1, J. W. S. Liu 2 and J. K. Zao 3 1 Department of Computer Science and Information Engineering, National Yunlin

More information

Appendix (unedited, as supplied by the authors)

Appendix (unedited, as supplied by the authors) Appendix (unedited, as supplied by the authors) Details of the mathematical model The model used for the simulations in this manuscript was adapted from a previously described model of HCV transmission

More information

An application of topological relations of fuzzy regions with holes

An application of topological relations of fuzzy regions with holes Chapter 5 An application of topological relations of fuzzy regions with holes 5.1 Introduction In the last two chapters, we have provided theoretical frameworks for fuzzy regions with holes in terms of

More information

CS 322: (Social and Information) Network Analysis Jure Leskovec Stanford University

CS 322: (Social and Information) Network Analysis Jure Leskovec Stanford University CS 322: (Social and Information) Network Analysis Jure Leskovec Stanford University Probabilistic models of networkdiffusion How cascades spread in real life: Viral marketing Blogs Group membership Last

More information

S pace represents, in many circumstances, a relevant feature in the spread of an infectious disease1. This is the

S pace represents, in many circumstances, a relevant feature in the spread of an infectious disease1. This is the SUBJECT AREAS: DISEASES COMPUTATIONAL BIOLOGY MODELLING AND THEORY NETWORKS AND SYSTEMS BIOLOGY Received 3 May 01 Accepted 7 June 01 Published 7 June 01 Correspondence and requests for materials should

More information

Supplement for: CD4 cell dynamics in untreated HIV-1 infection: overall rates, and effects of age, viral load, gender and calendar time.

Supplement for: CD4 cell dynamics in untreated HIV-1 infection: overall rates, and effects of age, viral load, gender and calendar time. Supplement for: CD4 cell dynamics in untreated HIV-1 infection: overall rates, and effects of age, viral load, gender and calendar time. Anne Cori* 1, Michael Pickles* 1, Ard van Sighem 2, Luuk Gras 2,

More information

Global Connectivity and the Spread of Infectious Diseases

Global Connectivity and the Spread of Infectious Diseases Nova Acta Leopoldina NF Nr. 419, 129 136 (2017) Global Connectivity and the Spread of Infectious Diseases Dirk Brockmann (Berlin) 1 Abstract The spread of infectious diseases has become a global concern.

More information

SUPPLEMENTARY MATERIAL. Impact of Vaccination on 14 High-Risk HPV type infections: A Mathematical Modelling Approach

SUPPLEMENTARY MATERIAL. Impact of Vaccination on 14 High-Risk HPV type infections: A Mathematical Modelling Approach SUPPLEMENTARY MATERIAL Impact of Vaccination on 14 High-Risk HPV type infections: A Mathematical Modelling Approach Simopekka Vänskä, Kari Auranen, Tuija Leino, Heini Salo, Pekka Nieminen, Terhi Kilpi,

More information

arxiv: v1 [cs.si] 29 Jan 2018

arxiv: v1 [cs.si] 29 Jan 2018 Detecting the impact of public transit on the transmission of epidemics Zhanwei Du 1,* and Yuan Bai 1 1 Jilin University, Changchun, Jilin, 130012, China * duzhanwei0@gmail.com ABSTRACT arxiv:1801.09333v1

More information

MATHEMATICAL STUDY OF BITING RATES OF MOSQUITOES IN TRANSMISSION OF DENGUE DISEASE

MATHEMATICAL STUDY OF BITING RATES OF MOSQUITOES IN TRANSMISSION OF DENGUE DISEASE ORIGINAL RESEARCH ARTICLE OPEN ACCESS MATHEMATICAL STUDY OF BITING RATES OF MOSQUITOES IN TRANSMISSION OF DENGUE DISEASE *G. R. Phaijoo, D. B. Gurung Department of Natural Sciences (Mathematics), School

More information

Optimal control of an emergency room triage and treatment process

Optimal control of an emergency room triage and treatment process Optimal control of an emergency room triage and treatment process Gabriel Zayas-Cabán 1 Mark E. Lewis 1 Jungui Xie 2 Linda V. Green 3 1 Cornell University Ithaca, NY 2 University of Science and Technology

More information

Unit 1 Exploring and Understanding Data

Unit 1 Exploring and Understanding Data Unit 1 Exploring and Understanding Data Area Principle Bar Chart Boxplot Conditional Distribution Dotplot Empirical Rule Five Number Summary Frequency Distribution Frequency Polygon Histogram Interquartile

More information

Influence of overweight and obesity on the diabetes in the world on adult people using spatial regression

Influence of overweight and obesity on the diabetes in the world on adult people using spatial regression International Journal of Advances in Intelligent Informatics ISSN: 2442-6571 149 Influence of overweight and obesity on the diabetes in the world on adult people using spatial regression Tuti Purwaningsih

More information

Title: Understanding the role of linker histone in DNA packaging with mathematical modelling

Title: Understanding the role of linker histone in DNA packaging with mathematical modelling Gustavo Carrero Araujo, Athabasca University Title: Understanding the role of linker histone in DNA packaging with mathematical modelling Abstract: When we think of the approximate average length of DNA

More information

The Chemostat: Stability at Steady States. Chapter 5: Linear & Non-Linear Interaction Models. So, in dimensional form, α 1 > 1 corresponds to

The Chemostat: Stability at Steady States. Chapter 5: Linear & Non-Linear Interaction Models. So, in dimensional form, α 1 > 1 corresponds to Introduction & Simple Models Logistic Growth Models The Chemostat: Stability at Steady States 1 So, in dimensional form, α 1 > 1 corresponds to K max < V F. As K max is max bacterial repro rate with unlimited

More information

Study on control of bird flu outbreak within a poultry farm

Study on control of bird flu outbreak within a poultry farm ANZIAM J. 51 (EMAC009) pp.c668 C681, 010 C668 Study on control of bird flu outbreak within a poultry farm T. Delia Nova 1 H. Mawengkang M. Watanabe 3 (Received 10 July 010; revised 8 September 010) Abstract

More information

The mathematics of diseases

The mathematics of diseases 1997 2004, Millennium Mathematics Project, University of Cambridge. Permission is granted to print and copy this page on paper for non commercial use. For other uses, including electronic redistribution,

More information

Self-organizing continuous attractor networks and path integration: one-dimensional models of head direction cells

Self-organizing continuous attractor networks and path integration: one-dimensional models of head direction cells INSTITUTE OF PHYSICS PUBLISHING Network: Comput. Neural Syst. 13 (2002) 217 242 NETWORK: COMPUTATION IN NEURAL SYSTEMS PII: S0954-898X(02)36091-3 Self-organizing continuous attractor networks and path

More information

Stochastic and Numerical Modeling of HIV/AIDS. Spread in a Complex System and Its Application to. the HIV Cases in Indonesia

Stochastic and Numerical Modeling of HIV/AIDS. Spread in a Complex System and Its Application to. the HIV Cases in Indonesia Applied Mathematical Sciences, Vol. 9, 2015, no. 122, 6095-6106 HIKAI Ltd, www.m-hikari.com http://dx.doi.org/10.12988/ams.2015.59564 Stochastic and Numerical Modeling of HIV/AIDS Spread in a Complex System

More information

Possible Consequences of Inhomogeneous Suborgan Distribution of Dose and the Linear No-Threshold Dose-Effect Relationship

Possible Consequences of Inhomogeneous Suborgan Distribution of Dose and the Linear No-Threshold Dose-Effect Relationship Possible Consequences of Inhomogeneous Suborgan Distribution of Dose and the Linear No-Threshold Dose-Effect Relationship Balázs G. Madas, Imre Balásházy Centre for Energy Research, Hungarian Academy of

More information

Hybrid Propagation Method Based on Gaussian Beam Summation (GBS)

Hybrid Propagation Method Based on Gaussian Beam Summation (GBS) Hybrid Propagation Method Based on Gaussian Beam Summation (GBS) Asaf Harel, Ehud Heyman June 19, 2014 UWA Symposium June 19, 2014 UWA Symposium 11/ Asaf Harel, Ehud Heyman GBSBased Hybrid Propagation

More information

Driving forces of researchers mobility

Driving forces of researchers mobility Driving forces of researchers mobility Supplementary Information Floriana Gargiulo 1 and Timoteo Carletti 1 1 NaXys, University of Namur, Namur, Belgium 1 Data preprocessing The original database contains

More information

Epidemics on networks and early stage vaccination

Epidemics on networks and early stage vaccination Mathematical Statistics Stockholm University Epidemics on networks and early stage vaccination Shaban Mbare Research Report 27:12 Licentiate thesis ISSN 165-377 Postal address: Mathematical Statistics

More information

Structured models for dengue epidemiology

Structured models for dengue epidemiology Structured models for dengue epidemiology submitted by Hannah Woodall for the degree of Doctor of Philosophy of the University of Bath Department of Mathematical Sciences September 24 COPYRIGHT Attention

More information

Power Blackouts and the Domino Effect: Real-Life examples and Modeling

Power Blackouts and the Domino Effect: Real-Life examples and Modeling Power Blackouts and the Domino Effect: Real-Life examples and Modeling Ingve Simonsen Dep. of Physics, NTNU (Trondheim) Collaborators: Lubos Buzna, Zilina Karsten Peters, Dresden Stefan Bornholdt, Bremen

More information

Rolls,E.T. (2016) Cerebral Cortex: Principles of Operation. Oxford University Press.

Rolls,E.T. (2016) Cerebral Cortex: Principles of Operation. Oxford University Press. Digital Signal Processing and the Brain Is the brain a digital signal processor? Digital vs continuous signals Digital signals involve streams of binary encoded numbers The brain uses digital, all or none,

More information

Modeling Consequences of Reduced Vaccination Levels on the Spread of Measles

Modeling Consequences of Reduced Vaccination Levels on the Spread of Measles Bridgewater State University Virtual Commons - Bridgewater State University Honors Program Theses and Projects Undergraduate Honors Program 5-2016 Modeling Consequences of Reduced Vaccination Levels on

More information

BioDiaspora. Evidence-Based Decision-Making. Kamran Khan MD, MPH, FRCPC

BioDiaspora. Evidence-Based Decision-Making. Kamran Khan MD, MPH, FRCPC BioDiaspora Evidence-Based Decision-Making Kamran Khan MD, MPH, FRCPC Associate Professor of Infectious Diseases University of Toronto Infectious Disease Physician St. Michael s Hospital Globalization

More information

Equilibrium Selection In Coordination Games

Equilibrium Selection In Coordination Games Equilibrium Selection In Coordination Games Presenter: Yijia Zhao (yz4k@virginia.edu) September 7, 2005 Overview of Coordination Games A class of symmetric, simultaneous move, complete information games

More information

Design of Low-Power CMOS Cell Structures Using Subthreshold Conduction Region

Design of Low-Power CMOS Cell Structures Using Subthreshold Conduction Region International Journal of Scientific & Engineering Research, Volume 2, Issue 2, February-2011 1 Design of Low-Power CMOS Cell Structures Using Subthreshold Conduction Region Vishal Sharma, Sanjay Kumar

More information

On indirect measurement of health based on survey data. Responses to health related questions (items) Y 1,..,Y k A unidimensional latent health state

On indirect measurement of health based on survey data. Responses to health related questions (items) Y 1,..,Y k A unidimensional latent health state On indirect measurement of health based on survey data Responses to health related questions (items) Y 1,..,Y k A unidimensional latent health state A scaling model: P(Y 1,..,Y k ;α, ) α = item difficulties

More information

A Model for the CD4 Cell Counts in an HIV/AIDS Patient and its Application in Treatment Interventions

A Model for the CD4 Cell Counts in an HIV/AIDS Patient and its Application in Treatment Interventions American Journal of Infectious Diseases (): 6-65, 5 ISSN: 553-63 5 Science Publications A Model for the CD4 Cell Counts in an HIV/AIDS Patient and its Application in Treatment Interventions Richard O.

More information

Spatio-temporal modelling and probabilistic forecasting of infectious disease counts

Spatio-temporal modelling and probabilistic forecasting of infectious disease counts Spatio-temporal modelling and probabilistic forecasting of infectious disease counts Sebastian Meyer Institute of Medical Informatics, Biometry, and Epidemiology Friedrich-Alexander-Universität Erlangen-Nürnberg,

More information

Age-specific contacts and travel patterns in the spatial spread of 2009 H1N1 influenza pandemic.

Age-specific contacts and travel patterns in the spatial spread of 2009 H1N1 influenza pandemic. Age-specific contacts and travel patterns in the spatial spread of 2009 H1N1 influenza pandemic. Andrea Apolloni, Chiara Poletto, Vittoria Colizza To cite this version: Andrea Apolloni, Chiara Poletto,

More information

An Introduction to Small-World and Scale-Free Networks

An Introduction to Small-World and Scale-Free Networks An Introduction to Small-World and Scale-Free Networks -FREE DEREK Department of Mathematics and Statistics California State University, Long Beach Derek.Sollberger@gmail.com WITHOUT -FREE -FREE EPIDEMICS

More information

A Game Theoretical Approach for Hospital Stockpile in Preparation for Pandemics

A Game Theoretical Approach for Hospital Stockpile in Preparation for Pandemics Proceedings of the 2008 Industrial Engineering Research Conference J. Fowler and S. Mason, eds. A Game Theoretical Approach for Hospital Stockpile in Preparation for Pandemics Po-Ching DeLaurentis School

More information

Modeling Imatinib-Treated Chronic Myeloid Leukemia

Modeling Imatinib-Treated Chronic Myeloid Leukemia Modeling Imatinib-Treated Chronic Myeloid Leukemia Cara Peters cpeters3@math.umd.edu Advisor: Dr. Doron Levy dlevy@math.umd.edu Department of Mathematics Center for Scientific Computing and Mathematical

More information

Determining the Optimal Search Area for a Serial Criminal

Determining the Optimal Search Area for a Serial Criminal Determining the Optimal Search Area for a Serial Criminal Mike O Leary Department of Mathematics Towson University Joint Mathematics Meetings Washington DC, 2009 Mike O Leary (Towson University) Optimal

More information

Supplementary Materials: Identifying critical transitions and their leading biomolecular networks in complex diseases

Supplementary Materials: Identifying critical transitions and their leading biomolecular networks in complex diseases Supplementary Materials: Identifying critical transitions and their leading biomolecular networks in complex diseases Rui Liu, Meiyi Li, Zhiping Liu, Jiarui Wu, Luonan Chen, Kazuyuki Aihara Contents A

More information

Steven Farber McMaster University Antonio Páez McMaster University Kay Axhausen ETH Zurich

Steven Farber McMaster University Antonio Páez McMaster University Kay Axhausen ETH Zurich Steven Farber McMaster University Antonio Páez McMaster University Kay Axhausen ETH Zurich Analysis of transportation systems has adopted more ideas from the activity paradigm We now recognize that travel

More information

Theta sequences are essential for internally generated hippocampal firing fields.

Theta sequences are essential for internally generated hippocampal firing fields. Theta sequences are essential for internally generated hippocampal firing fields. Yingxue Wang, Sandro Romani, Brian Lustig, Anthony Leonardo, Eva Pastalkova Supplementary Materials Supplementary Modeling

More information

Using dynamic prediction to inform the optimal intervention time for an abdominal aortic aneurysm screening programme

Using dynamic prediction to inform the optimal intervention time for an abdominal aortic aneurysm screening programme Using dynamic prediction to inform the optimal intervention time for an abdominal aortic aneurysm screening programme Michael Sweeting Cardiovascular Epidemiology Unit, University of Cambridge Friday 15th

More information

A Neural Network Architecture for.

A Neural Network Architecture for. A Neural Network Architecture for Self-Organization of Object Understanding D. Heinke, H.-M. Gross Technical University of Ilmenau, Division of Neuroinformatics 98684 Ilmenau, Germany e-mail: dietmar@informatik.tu-ilmenau.de

More information

The roadmap. Why do we need mathematical models in infectious diseases. Impact of vaccination: direct and indirect effects

The roadmap. Why do we need mathematical models in infectious diseases. Impact of vaccination: direct and indirect effects Mathematical Models in Infectious Diseases Epidemiology and Semi-Algebraic Methods Why do we need mathematical models in infectious diseases Why do we need mathematical models in infectious diseases Why

More information

Cancer Treatment Using Multiple Chemotheraputic Agents Subject to Drug Resistance

Cancer Treatment Using Multiple Chemotheraputic Agents Subject to Drug Resistance Cancer Treatment Using Multiple Chemotheraputic Agents Subject to Drug Resistance J. J. Westman Department of Mathematics University of California Box 951555 Los Angeles, CA 90095-1555 B. R. Fabijonas

More information

Modelling the Dynamic of the Foot-and Mouth Disease in England 2001

Modelling the Dynamic of the Foot-and Mouth Disease in England 2001 Modelling the Dynamic of the Foot-and Mouth Disease in England 2001 Seminar on Veterinary Epidemiology Franz Rubel Budapest, 28 May 2003 Mathematical Epidemiology Group, Institute for Medical Physics and

More information

Parasites transmitted by vectors

Parasites transmitted by vectors Parasites transmitted by vectors Often very specific vector-parasite relationships Biomphalaria sp. - Schistosoma mansoni Anopheles sp. Plasmodium falciparum Simulium sp. Onchocerca volvulis Some more

More information

L4, Modeling using networks and other heterogeneities

L4, Modeling using networks and other heterogeneities L4, Modeling using networks and other heterogeneities July, 2017 Different heterogeneities In reality individuals behave differently both in terms of susceptibility and infectivity given that a contact

More information

Risk of a second cancer after radiotherapy

Risk of a second cancer after radiotherapy Risk of a second cancer after radiotherapy Francesco d Errico University of Pisa, Italy Yale University, USA Medical radiological procedures worldwide 2.5 billion diagnostic radiological examinations 78%

More information

Review Article A Modeling and Experiment Framework for the Emergency Management in AHC Transmission

Review Article A Modeling and Experiment Framework for the Emergency Management in AHC Transmission Computational and Mathematical Methods in Medicine, Article ID 897532, 18 pages http://dx.doi.org/1.1155/214/897532 Review Article A Modeling and Experiment Framework for the Emergency Management in AHC

More information

Does ramp-up reduce risks to marine mammals? Assessing the effectiveness of a mitigation method Paul Wensveen & Sander von Benda-Beckmann

Does ramp-up reduce risks to marine mammals? Assessing the effectiveness of a mitigation method Paul Wensveen & Sander von Benda-Beckmann Does ramp-up reduce risks to marine mammals? Assessing the effectiveness of a mitigation method Paul Wensveen & Sander von Benda-Beckmann Sea Mammals and Sonar Symposium 27 October 2015, St Andrews, Scotland,

More information

Topology of prion proteins

Topology of prion proteins Tohoku Knot Seminar(Oct. 15, 2011) Topology of prion proteins A joint work with Kayo Yoshida Akio Kawauchi Osaka City University Preprint is available from http://www.sci.osakacu.ac.jp/~kawauchi/topologyofprionproteins.pdf

More information

Mathematics Meets Oncology

Mathematics Meets Oncology .. Mathematics Meets Oncology Mathematical Oncology Philippe B. Laval Kennesaw State University November 12, 2011 Philippe B. Laval (Kennesaw State University)Mathematics Meets Oncology November 12, 2011

More information

Nerve. (2) Duration of the stimulus A certain period can give response. The Strength - Duration Curve

Nerve. (2) Duration of the stimulus A certain period can give response. The Strength - Duration Curve Nerve Neuron (nerve cell) is the structural unit of nervous system. Nerve is formed of large numbers of nerve fibers. Types of nerve fibers Myelinated nerve fibers Covered by myelin sheath interrupted

More information

Epidemiological Model of HIV/AIDS with Demographic Consequences

Epidemiological Model of HIV/AIDS with Demographic Consequences Advances in Applied Mathematical Biosciences. ISSN 2248-9983 Volume 5, Number 1 (2014), pp. 65-74 International Research Publication House http://www.irphouse.com Epidemiological Model of HIV/AIDS with

More information

Inter-country mixing in HIV transmission clusters: A pan-european phylodynamic study

Inter-country mixing in HIV transmission clusters: A pan-european phylodynamic study Inter-country mixing in HIV transmission clusters: A pan-european phylodynamic study Prabhav Kalaghatgi Max Planck Institute for Informatics March 20th 2013 HIV epidemic (2009) Prabhav Kalaghatgi 2/18

More information

Regression Discontinuity Analysis

Regression Discontinuity Analysis Regression Discontinuity Analysis A researcher wants to determine whether tutoring underachieving middle school students improves their math grades. Another wonders whether providing financial aid to low-income

More information

Discrimination and Generalization in Pattern Categorization: A Case for Elemental Associative Learning

Discrimination and Generalization in Pattern Categorization: A Case for Elemental Associative Learning Discrimination and Generalization in Pattern Categorization: A Case for Elemental Associative Learning E. J. Livesey (el253@cam.ac.uk) P. J. C. Broadhurst (pjcb3@cam.ac.uk) I. P. L. McLaren (iplm2@cam.ac.uk)

More information

Containing Acute Disease Outbreak APAMI Digital Ring Fence: A novel GIS-based approach to contain Emerging Infectious Diseases (EIDs)

Containing Acute Disease Outbreak APAMI Digital Ring Fence: A novel GIS-based approach to contain Emerging Infectious Diseases (EIDs) APAMI 2006 27-29 October 2006, Taipei Digital Ring Fence: A novel GIS-based approach to contain Emerging Infectious Diseases (EIDs) presented by K C Lun Immediate Past President, International Medical

More information

Jonathan D. Sugimoto, PhD Lecture Website:

Jonathan D. Sugimoto, PhD Lecture Website: Jonathan D. Sugimoto, PhD jons@fredhutch.org Lecture Website: http://www.cidid.org/transtat/ 1 Introduction to TranStat Lecture 6: Outline Case study: Pandemic influenza A(H1N1) 2009 outbreak in Western

More information

Lesson 1: Distributions and Their Shapes

Lesson 1: Distributions and Their Shapes Lesson 1 Name Date Lesson 1: Distributions and Their Shapes 1. Sam said that a typical flight delay for the sixty BigAir flights was approximately one hour. Do you agree? Why or why not? 2. Sam said that

More information

SUPPLEMENTAL MATERIAL

SUPPLEMENTAL MATERIAL 1 SUPPLEMENTAL MATERIAL Response time and signal detection time distributions SM Fig. 1. Correct response time (thick solid green curve) and error response time densities (dashed red curve), averaged across

More information

The Message or the Messenger? Inferring Virality and Diffusion Structure from Online Petition Signature Data

The Message or the Messenger? Inferring Virality and Diffusion Structure from Online Petition Signature Data The Message or the Messenger? Inferring Virality and Diffusion Structure from Online Petition Signature Data Chi Ling Chan, Justin Lai, Bryan Hooi*, Todd Davies Stanford University * Carnegie Mellon University

More information

2 Motivation from two dependent Markov Chains

2 Motivation from two dependent Markov Chains Modeling treatment costs associated with a multi-stage pandemic Michael A. Ekhaus Gibraltar Analytical Minneapolis, Minnesota Email: mekhaus@gibraltaranalytical.com Abstract Abstract: Introduced is an

More information

A Two-layered Model for the Analysis of Arterial Rheology

A Two-layered Model for the Analysis of Arterial Rheology IJCSIT International Journal of Computer Science and Information Technology, Vol., o., June, pp. 37- A Two-layered Model for the Analysis of Arterial Rheology Sapna Singh Department of Mathematics, Harcourt

More information

Statistics and Probability

Statistics and Probability Statistics and a single count or measurement variable. S.ID.1: Represent data with plots on the real number line (dot plots, histograms, and box plots). S.ID.2: Use statistics appropriate to the shape

More information

CHAPTER 6 HUMAN BEHAVIOR UNDERSTANDING MODEL

CHAPTER 6 HUMAN BEHAVIOR UNDERSTANDING MODEL 127 CHAPTER 6 HUMAN BEHAVIOR UNDERSTANDING MODEL 6.1 INTRODUCTION Analyzing the human behavior in video sequences is an active field of research for the past few years. The vital applications of this field

More information

Linear Ultrasonic Wave Propagation in Biological Tissues

Linear Ultrasonic Wave Propagation in Biological Tissues Indian Journal of Biomechanics: Special Issue (NCBM 7-8 March 29) Linear Ultrasonic Wave Propagation in Biological Tissues Narendra D Londhe R. S. Anand 2, 2 Electrical Engineering Department, IIT Roorkee,

More information

Simulation of HIV/AIDS distribution using GIS based cellular automata model.

Simulation of HIV/AIDS distribution using GIS based cellular automata model. Biomedical Research 2017; 28 (9): 4053-4057 ISSN 0970-938X www.biomedres.info Simulation of HIV/AIDS distribution using GIS based cellular automata model. Shu Yang 1, Daihai He 2, Jing Luo 3, Weizhong

More information

Adults and Children estimated to be living with HIV, 2013

Adults and Children estimated to be living with HIV, 2013 Adults and Children estimated to be living with HIV, 2013 Spending on HIV/AIDS Recent increase in the available money for HIV/AIDS The Gates foundation alone has over $60 billion Present plans are to hold

More information

Beyond bumps: Spiking networks that store sets of functions

Beyond bumps: Spiking networks that store sets of functions Neurocomputing 38}40 (2001) 581}586 Beyond bumps: Spiking networks that store sets of functions Chris Eliasmith*, Charles H. Anderson Department of Philosophy, University of Waterloo, Waterloo, Ont, N2L

More information

CHAPTER 1. Network Models In Epidemiology: An Overview

CHAPTER 1. Network Models In Epidemiology: An Overview September 11, 005 18:8 WSPC/Trim Size: 9in x 6in for Review Volume network CHAPTER 1 Network Models In Epidemiology: An Overview Alun L. Lloyd Biomathematics Graduate Program and Department of Mathematics,

More information

EXPECTED TIME TO CROSS THE ANTIGENIC DIVERSITY THRESHOLD IN HIV INFECTION USING SHOCK MODEL APPROACH ABSTRACT

EXPECTED TIME TO CROSS THE ANTIGENIC DIVERSITY THRESHOLD IN HIV INFECTION USING SHOCK MODEL APPROACH ABSTRACT EXPECTED TIME TO CROSS THE ANTIGENIC DIVERSITY THRESHOLD IN HIV INFECTION USING SHOCK MODEL APPROACH R.Elangovan and R.Ramajayam * Department of Statistics, Annamalai University, Annamalai Nagar- 68 2

More information