Outbreaks of Zika Virus: What Do We Know? Presented by Dr Jonathan Darbro Mosquito Control Lab, QIMR Berhgofer 15 September 2016
|
|
- Augustine Wilson
- 5 years ago
- Views:
Transcription
1 Outbreaks of Zika Virus: What Do We Know? Presented by Dr Jonathan Darbro Mosquito Control Lab, QIMR Berhgofer 15 September 2016
2 Overview History Distribution Modes of Transmission Symptoms Some Causal Factors Where to from here QIMR Berghofer Medical Research Institute 2
3 Zika Virus Ashraf et al Viruses 7(1): QIMR Berghofer Medical Research Institute 3
4 First Contact with Zika Virus Isolated in 1947 from rhesus monkey 6.1% seroprevalence in Uganda First case 1953 (Nigeria) : 13 reported cases QIMR Berghofer Medical Research Institute 4
5 Areas in Which Zika Virus Infections in Humans Have Been Noted in the Past Decade (as of March 2016). Petersen LR et al. N Engl J Med 2016;374:
6 January 2016 vs. September 2016 (PAHO/WHO)
7 Case Count (Americas) Suspected Cases Confirmed Cases 494, ,122 Brazil, Puerto Rico, Colombia, Mexico Deaths 13 Brazil, Suriname, Puerto Rico Confirmed congenital syndrome 1950 Brazil, Colombia, USA PAHO/WHO 8 September 2016 QIMR Berghofer Medical Research Institute 7
8 Modes of Transmission Observed Mosquito bite Sexual Mother to child Theoretical (Virus Detected) Blood transfusion Tissue/organ transplant Breast Milk Urine Saliva Tears Laboratory exposure QIMR Berghofer Medical Research Institute 8
9 Zika Virus-Mosquito Transmission Cycle. Intrinsic incubation period (mosquito): 4-11 days Viraemic period (human): 3-5 days Petersen LR et al. N Engl J Med 2016;374:
10 Known Mosquito Vectors of Zika Urban Aedes aegypti Aedes albopictus Aedes hensilli (Yap) Aedes polynesiensis (F.P.) Sylvan (jungle) Aedes africanus Aedes luteocephalus Aedes furcifer Aedes taylori Ae. aegypti Ae. albopictus
11 Aedes aegypti Primary Zika vector Feeds on humans Tropical and subtropical climate Breeds in containers near human dwellings Also vector of dengue, chikungunya, yellow fever Bhatt et al Nature 496:
12 Aedes albopictus Secondary vector Feeds on humans and other hosts Tropical, subtropical, temperate climate Breeds in containers near human dwellings Also vector of chikungunya, dengue Suspected vector of 22 viruses
13 Sexual Transmission of Zika Virus First confirmed in 2008 Cases reported in 11 countries Mostly vaginal sex One anal sex transmission One transmission via vaginal fluid One asymptomatic transmission QIMR Berghofer Medical Research Institute 13
14 Sexual Transmission of Zika Virus Virus persistence in semen Virus titre as high as 100,000x blood serum As long as 41 days between onset of symptoms and index case Zika RNA detected as long as 188 days Virus persistence in vaginal fluid Less well known 5 days after symptom onset QIMR Berghofer Medical Research Institute 14
15 Most Zika Symptoms Similar to Dengue ~80% of cases asymptomatic Fever Rash Arthralgia Myalgia Retro-orbital pain Vomiting Conjunctivitis QIMR Berghofer Medical Research Institute 15
16 Zika Virus Infection Associated with Guillain-Barré Syndrome (GBS) Immune system attacks peripheral nervous system and damages myelin sheaths Symmetrical weakness or tingling sensation in legs, can spread to arms and upper body Incidence normally 1-4 per 100,000 Case control study from French Polynesia outbreak 41/42 GBS patients had anti-zika IgG or IgM 42/42 had neutralising antibodies (vs. 56% in control group) Cao-Lormeau et al Lancet. 387(10027): QIMR Berghofer Medical Research Institute 16
17 Zika Virus and Congenital Microcephaly Reduction in brain volume motor disabilities speech impairment poor neurocognitive outcome behavioural issues Causes include: prenatal infections (e.g. rubella, cytomegalovirus, leptospirosis) maternal alcohol use hypertensive disorder Cauchemez et al Lancet 387(10033): QIMR Berghofer Medical Research Institute 17
18 Zika Virus and Congenital Microcephaly: Evidence Case-control study in French Polynesia found risk of microcephaly during first trimester was 95 cases per 100,000 (vs. 2 cases baseline) Complete ZIKV genome recovered from brain tissue of a fetus with microcephaly ZIKV found to infect human neural progenitor cells, causing cell death and attenuated hnpc growth. Cauchemez et al Lancet 387(10033): Mlakar et al NEJM 374: Tang et al Cell Stem Cell 18: 1-4. QIMR Berghofer Medical Research Institute 18
19 Why Is There a Zika Outbreak? QIMR Berghofer Medical Research Institute 19
20 Why Is There a Zika Outbreak? Y? Mosquito distributions haven t changed QIMR Berghofer Medical Research Institute 20
21 Why Is There a Zika Outbreak? Y? Mosquito distributions haven t changed Has the virus changed? Three ZIKV strains (East African, West African, Asian) All outbreaks since 2007: Asian strain Asian strain has been gradually evolving and spreading since at least 1966 NS1 protein (Asian) appears to be better adapted to human cells (de Melo Freire, unpublished) QIMR Berghofer Medical Research Institute 21
22 Does the Chikungunya Outbreak Offer Any Clues? Coffey et al Viruses 6(11): QIMR Berghofer Medical Research Institute 22
23 Does the Chikungunya Outbreak Offer Any Clues? Three geographical strains West African East African Asian Similar movement pattern Same mosquito vectors Different virus family A226V mutation in ECSA CHIKV strain E. Africa Ae. albopictus Asian Ae. aegypti Patterns of Human movement? Commercial / travel QIMR Berghofer Medical Research Institute 23
24 Why Is There a Zika Outbreak? Y? Mosquito distributions haven t changed No evidence the virus has changed (yet) Human movement patterns a possibility Combination of naïve host population and vulnerable health infrastructure Teixeira Rev. Inst. Med. Trop. S. Paulo 54 QIMR Berghofer Medical Research Institute 24
25 Zika: Moving Forward Most likely will be established Studies on viral pathogenesis underway Vaccine trials imminent Larocca et al Nature 536: Ae. aegypti population replacement with Wolbachia Render mosquitoes non virus-transmitting Aliota et al Scientific Reports 6: Conventional Aedes aegypti control critical Indoor residual spraying Larval source reduction QIMR Berghofer Medical Research Institute 25
26 Thank you
Epidemiology and entomology of the Zika virus outbreak
Epidemiology and entomology of the Zika virus outbreak M A T T H E W B A Y L I S I N S T I T U T E O F I N F E C T I O N A N D G L O B A L H E A L T H U N I V E R S I T Y O F L I V E R P O O L Zika in
More informationPublic Health Image Library. CDC/ Cynthia Goldsmith. Image #
Zika Virus Fredrick M. Abrahamian, D.O., FACEP, FIDSA Clinical Professor of Medicine UCLA School of Medicine Director of Education Department of Emergency Medicine Olive View-UCLA Medical Center Sylmar,
More informationWhat s Lurking out there??????
What s Lurking out there?????? Dave Warshauer, PhD, D(ABMM) Deputy Director, Communicable Diseases Wisconsin State Laboratory of Hygiene david.warshauer@slh.wisc.edu WISCONSIN STATE LABORATORY OF HYGIENE
More informationZika virus: a new global threat for Dr Gina McAllister Clinical Scientist, Virology
Zika virus: a new global threat for 2016 Dr Gina McAllister Clinical Scientist, Virology Moritz U. G. Kraemer and others The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus
More informationEuropean Centre for Disease Prevention and Control. Zika virus disease
European Centre for Disease Prevention and Control Zika virus disease Stockholm, 19 February 2016 Background information Zika virus is a member of the Flaviviridae family and transmitted by mosquitoes
More informationEverything you ever wanted to know about Zika Virus Disease
Everything you ever wanted to know about Zika Virus Disease (in 14 slides) Jon Temte, MD/PhD University of Wisconsin School of Medicine and Public Health 28 January 2016 Zika Virus mosquito-borne flavivirus
More informationZika virus: clinical and epidemiological features
Zika virus: clinical and epidemiological features Dominic Dwyer Medical Virologist, Westmead Hospital Director, ICPMR and Pathology West NSW Health Pathology dominic.dwyer@sydney.edu.au, Zika virus Flavivirus
More informationZika Virus. Centers for Disease Control and Prevention
Centers for Disease Control and Prevention Zika Virus Ingrid Rabe Medical Epidemiologist Arboviral Diseases Branch Centers for Disease Control and Prevention February 1, 2016 Zika Virus Single stranded
More informationZIKA VIRUS. John J. Russell MD May 27, 2016
John J. Russell MD May 27, 2016 HISTORY Discovered 1947 Zika Forest of Uganda in rhesus monkeys, thus the name Found in humans in Africa in 1952 Not considered a public health threat until outbreak in
More informationZika Virus: The Olympics and Beyond
Zika Virus: The Olympics and Beyond Alice Pong, MD Pediatric Infectious Diseases Rady Children s Hospital-San Diego University of California, San Diego Disclosures I have no disclosures to report 1 Objectives
More informationZIKA VIRUS. Epic and aspects of management
ZIKA VIRUS Epic and aspects of management Classification - Belong to the family Flaviviridae which are mosquitoes borne viruses such as Dengue virus ( DEN V ), West Nile virus ( WN V ), Yellow fever Virus
More informationGuidance for Investigation and Management of Zika Virus Infection
Guidance for Investigation and Management of Zika Virus Infection Update: February 11, 2016 Public Health Agency of Canada has issued recommendations from the Committee to Advise on Tropical Medicine and
More informationFIRST CONFIRMED CASE OF IMPORTED ZIKA VIRUS IN HOUSTON, TEXAS. Preventing Transmission
FIRST CONFIRMED CASE OF IMPORTED ZIKA VIRUS IN HOUSTON, TEXAS Preventing Transmission Objectives Discuss the epidemiology of Zika virus Describe the Zika case investigation of the first confirmed case
More information10/6/2016. Outline. Zika, Dengue, and Chikungunya Viruses in the Americas Oh My! Some Mosquito-Borne Arboviruses
Zika, Dengue, and Chikungunya Viruses in the Americas Oh My! Geoffrey A. Weinberg, M.D., FAAP, FIDSA, FPIDS Professor of Pediatrics Director, Pediatric HIV Program Division of Pediatric Infectious Diseases
More informationZika Virus. ZIKA VIRUS & PREGNANCY Stephen Champlin, M.D. FLAVIVIRIDAE VIRUS SPECTRUM. Virus family Flaviviridae
ZIKA VIRUS & PREGNANCY Stephen Champlin, M.D. Zika Virus Virus family Flaviviridae Positive sense, single-stranded RNA virus FLAVIVIRIDAE VIRUS SPECTRUM Arbovirus - spread by arthropods to mammals Flaviviridae
More informationWhen infections go viral Zika Virus
When infections go viral Zika Virus John Fangman, MD Associate Professor of Medicine (Infectious Diseases) Senior Medical Director of Ambulatory, Medical College Physicians Medical College of Wisconsin
More information*This response is constantly evolving and recommendations in this presentation may change over time, please call your district epidemiologist or a
*This response is constantly evolving and recommendations in this presentation may change over time, please call your district epidemiologist or a GDPH epidemiologist 404-657-2588, 8-5 pm M-F for current
More informationZika Virus Update. Partner Webinar 05/12/2016
Zika Virus Update Partner Webinar 05/12/2016 Today s presenters Patricia Quinlisk, MD, MPH, Medical Director /State Epidemiologist Ann Garvey, DVM, MPH, MA, State Public Health Veterinarian/ Deputy State
More informationZika Virus. Lee Green Vector-Borne Epidemiologist Indiana State Department of Health. April 13, 2016
Zika Virus Lee Green Vector-Borne Epidemiologist Indiana State Department of Health April 13, 2016 What Is It? Flavivirus WNV Dengue St. Louis Encephalitis Yellow Fever Tick Borne Encephalitis Single stranded
More informationZika Virus Basics. Flaviviridae Flavivirus Disease Vector Vaccine *Dengue (serotypes 1-4) Zika Virus Basics. Zika Virus Transmission Cycle
Zika: Infection,, and Protection Roxanne P. Liles, Ph.D., MLS(ASCP) CM Assistant Professor of Biology Louisiana State University at Alexandria 318-473-6518 rliles@lsua.edu Zika Virus Basics Virion: Enveloped
More informationTHE ZIKA VIRUS. August 3, Sonia G. Pandit, MPH MBA Chief Executive Officer The Pandit Group
THE ZIKA VIRUS August 3, 2016 Sonia G. Pandit, MPH MBA Chief Executive Officer The Pandit Group sonia@thepanditgroup.com 443-990-1372 www.thepanditgroup.com What Makes Zika Unique? Viral disease (Flavi
More informationA RELOOK AT ZIKA VIRAL INFECTION AND ITS LATEST OUTBREAK IN INDIA
24 th December 2018 A RELOOK AT ZIKA VIRAL INFECTION AND ITS LATEST OUTBREAK IN INDIA BACKGROUND Zika virus infection, which erupted on a large scale in 2015-2016, has infected more than 1.5 million people.
More informationAn Introduction to Dengue, Zika and Chikungunya Viruses
An Introduction to Dengue, Zika and Chikungunya Viruses Natalie Marzec, MD, MPH Zoonoses Epidemiologist 2017 Global Health and Disasters Course Objectives Arbovirus Overview Public Health Activities Clinical
More informationZika Virus Update for Emergency Care Providers
Zika Virus Update for Emergency Care Providers What is this Zika Virus? Jeff Doerr Epidemiologist Southeastern Idaho Public Health Zika Virus Single stranded RNA virus Genus Flavivirus, Family Flaviviridae
More informationZika Virus. Maternal & Fetal Effects. John P. Elliott, MD Medical Director, Valley Perinatal Services Phoenix, Arizona
Zika Virus Maternal & Fetal Effects John P. Elliott, MD Medical Director, Valley Perinatal Services Phoenix, Arizona Objective of Presentation Sneeka Peeka at Zika Disclosure I have nothing to disclose
More informationObjectives. Dengue, Chikungunya and Zika Virus Infection: Answers to Common Questions. Case 1. Dengue Introduction 10/15/2018
Dengue, Chikungunya and Zika Virus Infection: Answers to Common Questions Wayne Ghesquiere MD FRCPC Infectious Diseases Consultant Clinical Assistant Prof, UBC Victoria, BC Objectives Discuss common Arbovirus
More informationZIKA: is South Africa at risk? Lucille Blumberg National Institute for Communicable Diseases South Africa
ZIKA: is South Africa at risk? Lucille Blumberg National Institute for Communicable Diseases South Africa 18 th April 1947; Rhesus macaque (no 766) with fever Filtrable transmissable agent The absence
More informationZIKA Virus and Mosquito Management. ACCG Rosmarie Kelly, PhD MPH 30 April 16
ZIKA Virus and Mosquito Management ACCG Rosmarie Kelly, PhD MPH 30 April 16 What is Zika Virus? Zika virus (ZIKV) is a flavivirus related to yellow fever, dengue, West Nile, and Japanese encephalitis viruses.
More informationGeneral Description. Significance
General Description The Zika virus is a member of the Flavivirus family, and is a small, enveloped virus (easy to kill with a hospital disinfectant). Zika virus is an emerging mosquito-borne virus that
More informationZika Virus. Division of Infectious Disease Department of Internal Medicine Global Health Program Conference Dora Lebron, MD Alexandra Stang, MD
Zika Virus Division of Infectious Disease Department of Internal Medicine Global Health Program Conference Dora Lebron, MD Alexandra Stang, MD Zika Virus ZIKV is a mosquito-borne ssrna flavivirus from
More informationFY 2017 President s Budget Request Overview for the National Center on Birth Defects and Developmental Disabilities
National Center on Birth Defects and Developmental Disabilities FY 2017 President s Budget Request Overview for the National Center on Birth Defects and Developmental Disabilities Sascha Chaney Associate
More informationWaiting in the Wings: Emergence, Impact and Control of Mosquito-Borne Viruses
International Center for Enterprise Preparedness (InterCEP) Waiting in the Wings: Emergence, Impact and Control of Mosquito-Borne Viruses Web Forum On April 14, 2016, Kathryn A. Hanley, Professor in the
More informationZika Virus. Robert Wittler, MD
Zika Virus Robert Wittler, MD Disclosure I have no relevant financial relationships with the manufacturers(s) of any commercial products(s) and/or provider of commercial services discussed in this CME
More informationZika Virus. Disclosure. Zika Virus 8/26/2016
Zika Virus Robert Wittler, MD Disclosure I have no relevant financial relationships with the manufacturers(s) of any commercial products(s) and/or provider of commercial services discussed in this CME
More informationZIKA VIRUS. Causes, Symptoms, Treatment and Prevention
ZIKA VIRUS Causes, Symptoms, Treatment and Prevention Introduction Zika virus is spread to people through mosquito bites. The most common symptoms of Zika virus disease are fever, rash, joint pain, and
More informationMercer MRC A Newsletter for and about our volunteers
Mercer MRC A Newsletter for and about our volunteers May 2017 Volume 1, Issue 5 Brian Hughes, County Executive Marygrace Billek, Director, Dept. of Human Services Lyme Disease Awareness Month May is Lyme
More informationZika Virus Update. Florida Department of Health (DOH) Mark Lander. June 16, Florida Department of Health in Columbia County
Zika Virus Update Florida Department of Health (DOH) Mark Lander June 16, 2016 Florida Department of Health in Columbia County 1 Zika Virus Originally identified in Africa and Southeast Asia First identified
More informationTown of Wolfeboro New Hampshire Health Notice Wolfeboro Public Health Officer Information Sheet Zika Virus
Aedes Zika Virus Information Sheet Town of Wolfeboro New Hampshire Health Notice Wolfeboro Public Health Officer Information Sheet Zika Virus The Zika Virus is a mosquito borne illness spread by the Aedes
More informationZika Virus (ZIKV) Rosanna W Peeling London School of Hygiene & Tropical Medicine Director, International Diagnostics Centre.
Zika Virus (ZIKV) Rosanna W Peeling London School of Hygiene & Tropical Medicine Director, International Diagnostics Centre www.idx-dx.org ZiKa Virus (ZIKV) Zika virus (ZIKV) is an RNA virus of the Flaviviridae
More informationZika Virus Identifying an Emerging Threat. Florida Department of Health in Miami-Dade County Epidemiology, Disease Control, & Immunization Services
Zika Virus Identifying an Emerging Threat Florida Department of Health in Miami-Dade County Epidemiology, Disease Control, & Immunization Services What is Zika Virus? Zika virus is a vector-borne disease
More informationAs suggested by one fellow student, please consider the CDC's "Final Rules for Control of Communicable Diseases: Interstate and Foreign
As suggested by one fellow student, please consider the CDC's "Final Rules for Control of Communicable Diseases: Interstate and Foreign http://www.cdc.gov/quarantine/ aboutlawsregulationsquarantineisolatio
More informationWelcome All. Western Australia Oncology Menopause Endometriosis New Mothers
Welcome All Western Australia ZIKA VIRUS What s the latest? Dr Clay Golledge COUNTRIES WITH ONGOING ZIKA CIRCULATION American Samoa Curacao Guyana Nicaragua Tonga Barbados Dominican Republic Haiti Panama
More informationSPECIALIZED FAMILY CARE Provider Training
SPECIALIZED FAMILY CARE Provider Training Category: Health Issue Title: Zika Virus Materials: Centers for Disease Control Fact Sheet on Zika Virus Goal: Specialized Family Care Provider to learn the risks,
More informationZika: Deet, There It Is. Anna Powell, MD Reproductive Infectious Disease Fellow THEGOS
Zika: Deet, There It Is Anna Powell, MD Reproductive Infectious Disease Fellow THEGOS Disclosure I have no financial disclosures or conflicts of interest Lessons from Rubella At peak of rubella epidemic
More informationZika virus: Interim guidance information for LMCs (midwives), GPs and other health professionals dealing with Zika virus in pregnancy 5 February 2016
Zika virus: Interim guidance information for LMCs (midwives), GPs and other health professionals dealing with Zika virus in pregnancy 5 February 2016 This interim guidance is the result of consultation
More informationGeographic distribution ZIKV
Shelley M. Wood, RN, BSN, CEN March 16, 2016 Geographic distribution ZIKV 1947 2007 http://www.ncbi.nlm.nih.gov/pmc/articles/pmc2819875/ 1 Current Active Zika transmission WHO declared global health threat
More informationZika Virus What Every Woman Needs to Know
Zika Virus What Every Woman Needs to Know Carrie L. Byington, MD The Jean and Thomas McMullin Professor and Dean of Medicine Senior Vice President Health Science Center Vice Chancellor for Health Services
More informationZika virus infection Interim clinical guidance for Primary Care
Zika virus infection Interim clinical guidance for Primary Care Zika virus infection is a notifiable disease in Ireland under the Infectious Diseases (Amendment) Regulations 2016 (S.I.. 276 of 2016). All
More informationZIKA VIRUS OUTBREAK. JANET B. EDDY M.D. KU-WICHITA PGY2 OBSTETRICS AND GYNECOLOGY RESIDENCY Dominican Republic 2016
ZIKA VIRUS OUTBREAK JANET B. EDDY M.D. KU-WICHITA PGY2 OBSTETRICS AND GYNECOLOGY RESIDENCY Dominican Republic 2016 Zika time line 1947: 1 st isolated in rhesus monkey in Zika forest of Uganda 1 12/2013:
More informationThe Zika Crisis: Where, What and USG/WHO? Brian R. Moyer BRMoyer & Associates, LLC Bedford, NH
2016 National Biotechnology Conference, Boston, May 18th The Zika Crisis: Where, What and USG/WHO? Brian R. Moyer BRMoyer & Associates, LLC Bedford, NH 03110 bmoyernh@gmail.com 2016 National Biotechnology
More informationFocus. International #57. Dengue Fever, Chikungunya and the Zika Virus. Chikungunya
Dengue Fever, Chikungunya and the Zika Virus Arboviruses are a group of virus that can be transmitted between animals and humans, and they are common to humans and many vertebrates (mammals, birds, reptiles,
More informationModule Three About Zika Virus: What is Known and Not Known
Module Three About Zika Virus: What is Known and Not Known HOUSEKEEPING For educational and quality improvement purposes, this TeleECHO Clinic will be recorded By participating in this clinic, you are
More informationUpdates in Infectious Diseases. Kelley Struble, DO, MS St. John Physicians Infectious Disease September 30, 2016
Updates in Infectious Diseases Kelley Struble, DO, MS St. John Physicians Infectious Disease September 30, 2016 Disclosures No financial relationships or affiliations to disclose Overview Activity Pre-Test
More informationCarol M. Smith, M.D., M.P.H. Commissioner of Health and Mental Health Ulster County Department of Health and Mental Health May 20, 2016
Carol M. Smith, M.D., M.P.H. Commissioner of Health and Mental Health Ulster County Department of Health and Mental Health May 20, 2016 Michael Hein County Executive Zika virus was first discovered in
More informationZika Virus Dr Conor Doherty
Zika Virus Dr Conor Doherty Zika Virus Single stranded RNA enveloped icosahedral virus Flavivirus (e.g. dengue, yellow feve er) First described in Zika forest in Uganda in 1947 Initial enzootic monkey
More informationPresentation Overview
Presentation Overview Characteristics of Zika virus Characteristics of Zika virus infection Epidemiology and outbreaks Vector and transmission Clinical symptoms Diagnosis and testing Treatment and prevention
More informationEmerging TTIs How Singapore secure its blood supply
Emerging TTIs How Singapore secure its blood supply Ms Sally Lam Acting Division Director I Blood Supply Management I Blood Services Group I Health Sciences Outline Risk Mitigation Strategies to secure
More informationWrapping Our Heads Around the Outbreak
Wrapping Our Heads Around the Outbreak An Update on the Zika Virus P. Zach White, PharmD PGY1 Pharmacy Resident Mayo Eugenio Litta Children s Hospital Pharmacy Grand Rounds June 7, 2016 2015 MFMER slide-1
More informationRelevant Communicable Diseases in HCT/Ps
Relevant Communicable Diseases in HCT/Ps Phyllis I. Warkentin, MD Professor of Pathology and Pediatrics University of Nebraska Medical Center FACT Chief Medical Officer Relevant Communicable Diseases in
More informationZika. Nicole Evert, MS Zoonosis Control Branch Department of State Health Services Austin, Texas
Zika Nicole Evert, MS Zoonosis Control Branch Department of State Health Services Austin, Texas Family Flaviviridae, genus Flavivirus Vectors: Aedes aegypti and Aedes albopictus Maintained in a human-mosquito-human
More informationZika Virus Outbreak in the Americas. J. David Beckham MD Associate Professor of Medicine Division of Infectious diseases University of Colorado SOM
Zika Virus Outbreak in the Americas J. David Beckham MD Associate Professor of Medicine Division of Infectious diseases University of Colorado SOM Learning Objectives Understand the pathogenesis of West
More informationZika and Emerging Infectious Diseases. Clifford T. Mauriello, MD, FAAP Assistant Clinical Professor May 31, 2016
Zika and Emerging Infectious Diseases Clifford T. Mauriello, MD, FAAP Assistant Clinical Professor May 31, 2016 Famous Last Words The time has come to close the book on infectious diseases. We have basically
More informationClinical Policy: Diagnostic Testing for Zika Virus Reference Number: CP.MP.111 Effective Date: 06/16
Clinical Policy: Diagnostic Testing for Zika Virus Reference Number: CP.MP.111 Effective Date: 06/16 Last Review Date: 05/16 Revision Log See Important Reminder at the end of this policy for important
More informationFact Sheet for Health Care Providers: Interpreting Results from the Aptima Zika Virus assay. September 7, 2016
Dear Health Care Provider: Fact Sheet for Health Care Providers: Interpreting Results from the Aptima Zika Virus assay September 7, 2016 The U.S. Food and Drug Administration (FDA) has issued an Emergency
More informationKeeping Microbes at our Doorstep
Keeping Microbes at our Doorstep Mark Loeb MD McMaster University AMMI CANADA-CACMID Plenary on Global Health, Vancouver March 31, 2016 Infection Control Objectives The challenge of anticipating risk Proving
More information3/24/2017. CDC S Response to Zika ZIKA 101. Updated February 2, 2017 INTRODUCTION
CDC S Response to Zika ZIKA 101 Updated February 2, 2017 INTRODUCTION 1 What is Zika? Zika virus is spread to people primarily through the bite of an infected Aedes species mosquito (Ae. aegypti and Ae.
More informationZika Virus A Public Health Emergency of Olympic Proportions
Zika Virus A Public Health Emergency of Olympic Proportions Carrie L. Byington M.D.** HA and Edna Benning Presidential Professor Division of Pediatric Infectious Diseases ** With Thanks to Andrew Pavia,
More informationZika Virus in the Primary Care Setting
Zika Virus in the Primary Care Setting Monica McArthur, MD PhD Assistant Professor of Pediatrics Center for Vaccine Development University of Maryland School of Medicine Maryland Chapter ACP Meeting 17
More informationDuane J. Gubler, ScD Professor and Founding Director, Signature Research Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore
Duane J. Gubler, ScD Professor and Founding Director, Signature Research Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore AGENDA Other arboviruses with the potential for urban
More informationZKV and Guillain-Barré Syndrome. Silvia N. Tenembaum Pediatric Neurologist
ZKV and Guillain-Barré Syndrome Silvia N. Tenembaum Pediatric Neurologist ZIKA VIRUS- BACKGROUND INFORMATION Arbovirus (Arthropod-borne virus) 1- Flaviviridae family: Dengue (DENV) West Nile (WNV) Yellow
More informationZika Virus. It may be devastating, But we might just get one step ahead of it. Learning in Retirement Winter 2017 Daniel Burnside. photo: Newsweek.
Zika Virus It may be devastating, But we might just get one step ahead of it Learning in Retirement Winter 2017 Daniel Burnside photo: Newsweek.com INTRODUCTION TO VIRUSES STRUCTURE GENOME LIFE CYCLE
More informationZika Virus and Control Efforts in Arizona
Zika Virus and Control Efforts in Arizona Irene Ruberto, MPH, PhD Epidemiologist Office of Infectious Disease Services Arizona Department of Health Services November 10, 2016 Goal by Humbletree (cc by-nc
More informationWhat is Zika virus (Zika)?
Zika Virus Basics What is Zika virus (Zika)? Viral infection caused by the bite of an infected mosquito Linked to serious birth defects and other poor pregnancy outcomes in babies of mothers who were infected
More informationZIKA COLLABORATION MEETING: CLINICAL PERSPECTIVE. Julius L. Tonzel Vector-borne Diseases Epidemiologist Louisiana Office of Public Health
ZIKA COLLABORATION MEETING: CLINICAL PERSPECTIVE Julius L. Tonzel Vector-borne Diseases Epidemiologist Louisiana Office of Public Health DISCLOSURE STATEMENT The speakers, the speakers spouses, and the
More informationZika Virus. Report to the Standing Committee on Health. Dr. Graham Sher Chief Executive Officer, Canadian Blood Services
Dr. Graham Sher Chief Executive Officer, Services Dr. Dana Devine Chief Medical and Scientific Officer, Services Services Services is an arm s-length organization within the larger health-care system of
More informationAnnual Epidemiological Report
August 2018 Annual Epidemiological Report 1 Vectorborne disease in Ireland, 2017 Key Facts 2017: 10 cases of dengue were notified, corresponding to a crude incidence rate (CIR) of 0.2 per 100,000 population
More informationUPDATE ON ZIKA VIRUS INFECTION
IMPORTANCE UPDATE ON ZIKA VIRUS INFECTION Robert A. Broughton, M.D. Professor of Pediatrics Division of Infectious Diseases E-mail: rbrough@uky.edu WHO declared Zika a Public Health Emergency of International
More informationZIKA UPDATE NOVEMBER Ministry of Health, Barbados
ZIKA UPDATE NOVEMBER 2016 Ministry of Health, Barbados Zika Virus Disease Objectives By the end of this presentation you should be able: To recount the track of the current global Zika virus epidemic To
More informationZika Virus: Epidemiology and Preparedness NH Emergency Preparedness Conference June 9, 2016
Zika Virus: Epidemiology and Preparedness NH Emergency Preparedness Conference June 9, 2016 Abigail Mathewson, DVM, MPH Surveillance Epidemiology Program Manager State Public Health Veterinarian Abigail.mathewson@dhhs.nh.gov
More informationGBS and Zika Virus 1
GBS and Zika Virus 1 Zika virus classification and history The Zika virus is an arbovirus of the family Flaviviridae and the genus Flavivirus 1 Zika is an enveloped, icosahedral positive strand RNA virus
More informationZika Virus Disease: The New Public Health Emergency of International Concern
COMMENTARY Zika Virus Disease: The New Public Health Emergency of International Concern Onkarnath Chattopadhyay* Abstract Zika virus is an emerging mosquito-borne virus that was first identified in Uganda
More informationCHIKUNGUNYA VIRUS INFECTION. Cesar Ponce S. Medical Microbiologist and Parasitologist. Epidemiologist ADC Medical Microbiology Department Director
CHIKUNGUNYA VIRUS INFECTION Cesar Ponce S. Medical Microbiologist and Parasitologist. Epidemiologist ADC Medical Microbiology Department Director Curacao, Aug. 2014 TOPICS: Definition History Epidemiology
More informationCenters for Disease Control and Prevention Zika Virus in Pregnancy What Midwives Need To Know
Centers for Disease Control and Prevention Zika Virus in Pregnancy What Midwives Need To Know Margaret A. Lampe, RN, MPH Pregnancy and Birth Defects Surveillance Team Zika Virus Emergency Response U.S.
More informationMosquito Threats in LA County West Nile virus & Zika
Mosquito Threats in LA County West Nile virus & Zika The District at a Glance An independent special district formed under authority of the CA State Health and Safety Code Formed in 1952 and governed by
More informationZika Virus. Public Information Update/phone script. Date: March 28, 2016 Time: 11:00 a.m.
Zika Virus Public Information Update/phone script Date: March 28, 2016 Time: 11:00 a.m. ** Highlighted text indicates new, revised or updated information Note to operators: When people call asking questions
More informationThis memo is intended to provide information to NC clinicians and laboratories regarding diagnosis, management and reporting of Zika virus infection.
May 18, 2016 (replaces version dated March 31, 2016) To: From: North Carolina Health Care Providers and Laboratories Megan Davies, MD, State Epidemiologist Scott Zimmerman, DrPH, MPH, HCLD (ABB), State
More informationZika Virus Outbreak & Zika Congenital Syndrome. Regional Situation and Response
Zika Virus Outbreak & Zika Congenital Syndrome Regional Situation and Response PAHO Regional Meeting on the IBP Initiative, 15 June 2016 Lima, Peru 2 ZIKV in the Americas Impact and Lessons Learned ZIKV
More informationZIKA VIRUS. Annanya Gangopadhyay*, Shubhrajit Mantry, Abhinay Chhetri, Sudip das
ZIKA VIRUS Annanya Gangopadhyay*, Shubhrajit Mantry, Abhinay Chhetri, Sudip das, Himalayan Pharmacy Institute, Majhitar, Rangpo, E. Sikkim 737136, INDIA ARTICLE INFO: Article history: Received: 02 December
More informationZika Virus Outbreak An Update and Overview of the New York State Response
Zika Virus Outbreak An Update and Overview of the New York State Response Elizabeth Dufort, MD, FAAP Medical Director Division of Epidemiology New York State Department of Health Zika Virus- The Basics
More informationZika Outbreak Discussion
Zika Outbreak Discussion May 10, 2016 2016 Zurich Healthcare Customer Symposium Speakers Krishna Lynch Senior Healthcare Risk Consultant Zurich Clayton Shoup Business Director, Workers Compensation Zurich
More informationZika virus and laboratory diagnosis พ ไลพ นธ พ ธว ฒนะ ศ นย ว จ ยพ ฒนานว ตกรรม คณะเทคน คการแพทย มหาว ทยาล ยมห ดล 30 มกราคม 2560
Zika virus and laboratory diagnosis พ ไลพ นธ พ ธว ฒนะ ศ นย ว จ ยพ ฒนานว ตกรรม คณะเทคน คการแพทย มหาว ทยาล ยมห ดล 30 มกราคม 2560 Trop Med 30 Jan 2017 Discovery of Zika virus Apr 1947: The virus was isolated
More informationZIKA The Science & Practical Prevention
ZIKA The Science & Practical Prevention Bruce A. Donato, CSP, CHMM, CECD K & A First Aid & Safety, LLC 1 TRAINING DISCLAIMER These materials were developed by K & A First Aid, LLC, and are intended to
More informationTravel: Chikungunya, Zika,.. New worries
Travel: Chikungunya, Zika,.. New worries McGill Family Physician Refresher Course Dec 6, 2016 Makeda Semret, MD FRCP(C) Infectious Diseases/ Medical Microbiology Disclosures Funding from PHAC/CIHR/GSK/Novartis
More informationMosquito Control Update. Board of County Commissioners Work Session February 16, 2016
Mosquito Control Update Board of County Commissioners Work Session February 16, 2016 1 Presentation Overview Mosquito Control Division Mosquito-borne Diseases Control Techniques Outlook 2 Mosquito Control
More informationZika: Updates and Lessons Learned for Primary Care Clinicians
Zika: Updates and Lessons Learned for Primary Care Clinicians Kirsten Salmeen, MD Assistant Professor UCSF Obstetrics, Gynecology & Reproductive Sciences Maternal-Fetal Medicine I have no financial disclosures.
More informationFigure 1: Suspected and confirmed Zika virus cases reported by countries and territories in the Americas, by epidemiological week (EW)
Zika - Epidemiological Update 17 March 2016 Zika virus Incidence and trends Available data reported suggests a downward trend in reporting of Zika virus cases in the Region of the Americas (Figure 1).
More informationBuilding Zika preparedness in the Region of the Americas: research response
Update 23 September 2016 Building Zika preparedness in the Region of the Americas: research response Global Research Collaboration for Infectious Disease Preparedness meeting, Sao Paulo, November 30 Ludovic
More informationZika Virus: What We Know and Don t Know Meg Fisher, MD Medical Director. Disclosures. Objectives
Zika Virus: What We Know and Don t Know Meg Fisher, MD Medical Director Disclosures I have no financial disclosures. I do not plan to discuss off label uses of medications. Objectives Discuss the epidemiology
More informationZika Preparedness: Lessons for the U.S. Public Health System
Zika Preparedness: Lessons for the U.S. Public Health System Jeffrey Duchin, MD Health Officer, Public Health - Seattle & King County Professor in Medicine, Division of Infectious Diseases Adjunct Professor,
More informationZika Virus and Prevention in Mississippi
Mississippi State Department of Health Mississippi Morbidity Report Volume 32, Number 1 July 2016 Background: Zika Virus and Prevention in Mississippi Key Messages: Zika virus infection during pregnancy
More information