Classification of Infectious Disease Law in Japan
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1 Classification of Infectious Disease Law in Japan Type 1 (7) Type 2 (7) Type 3 (5) Type 4 (44) Viral Hemorrhagic Fever EVD Lassa Fever CCHF Marburg disease South American Hemorrhagic Fevers Plague Smallpox Tuberculosis MERS SARS Avian flu (H5N1/H7N9) Polio Diphtheria Cholera Typhoid fever Paratyphoid fever Dysentery EHEC infection Dengue Zika Chikungunya Yellow Fever Hepatitis A Legionellosis SFTS Rabies etc
2 Classification of Medical Center in Infectious Disease Law in Japan New Infectious Diseases Type I Infectious Diseases Type II Infectious Diseases Others 4 Medical institutions designated for specific infectious diseases 49 Medical institutions designated for type I infectious diseases 340 Medical institutions designated for type II infectious diseases not designated
3 Viral Hemorrhagic Fever
4 Viral Hemorrhagic Fever Classified as type 1 infectious diseases in law Ebola virus disease(evd), Lassa Fever, Crimean-Congo haemorrhagic fever(cchf), Marburg disease, South American Hemorrhagic Fevers Probable cases should be admitted to Specified / Category 1 infectious diseases hospital
5 Medical institutions designated for specific infectious diseases 4 Hospitals located near international airports Rinku Medical Center (Kansai Airport: KIX) Narita Red Cross Hospital (Narita Airport: NRT) NCGM (Haneda Airport: HND) Tokoname City Hospital (Centrair Airport: NGO)
6 Medical institutions designated for type I infectious diseases 49 Hospitals located almost every prefectures
7 agement protocol for people with a travel history to EVD endemic c quarantine NCGM NIID Euro Surveill. 2015;20(44).
8 Case definition of probable case during EVD outbreak 1) fever >38 C or clinical symptoms of EVD AND 2) history of contact with body fluids through EVD patients OR history of contact with bats and primates in endemic countries within 21 days.
9 4 suspected EVD cases Cases date countries ebola PCR duration of isolation final diagnosis 40s M 2014/10/27 unknown -ve 3 days unknown 60s M 2014/11/7 Liberia -ve 2 days Streptococcal pharyngitis 30s M 2014/12/29 Sierra Leone -ve 2 days sinusitis 70s F 2015/1/18 Sierra Leone -ve 3 days influenza A
10 12 34 MMWR Morb Mortal Wkly Rep Sep 11;64(35):981-4.
11 goggle N95 mask Face shield double gown double grove PPE in our institute shoes cover boot
12 FilmArray multiplex PCR system Simple: 2 minutes of hands-on time Easy: No precise measuring or pipetting required Fast: Turnaround time of about an hour
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14 Laboratory in ID unit. CBC and chems Rapid Test (Malaria, Dengue, etc..) PCR(EVD) LAMP(MERS, H5N1, etc )
15 MERS, avian flu
16 MERS, avian flu Classified as type 2 infectious diseases Probable cases should be admitted to Specified / Category 1 or 2 infectious diseases hospital More than 300 hospitals are assigned to care the patients of type 2 infectious diseases including MERS and avian flu
17 Medical institutions designated for type II infectious diseases 340 Hospitals located every secondary medical care area
18 The definition of suspected cases of MERS during outbreak in Korea (I)Patients with fever, respiratory symptoms, and the findings of pneumonia with history of travel to the MERS endemic countries within 14 days (II)Patients with fever, respiratory symptoms, and the history of medical visit, or exposure to the patient of MERS / camels, with history of travel to the MERS endemic countries within 14 days (III)Patients with fever, or respiratory symptoms, and the history of exposure to the confirmed MERS patients within 14 days
19 LAMP method for MERS-CoV detection Loop-mediated Isothermal Amplification is a simple, rapid, specific and cost-effective nucleic acid amplification method solely developed by Eiken Chemical Co., Ltd. It takes only 30 minutes to detect pathogens including MERS-CoV. We have multiplex LAMP method system in our laboratory in ID unit.
20 Chip Layout MERS Flu A Flu B H1pdm H3 H7 3cm gned by Dr. Kageyama, National Institute of Infectious Diseases, Japan and EIKEN
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Present State and Measures against Infectious Diseases in Tokyo
Asian Network of Major Cities 21 Asian Infectious Disease Project Present State and Measures against Infectious Diseases in History of Law on Infectious Diseases Revisions 1897 1999 23 Communicable Disease
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