#4 (Tuberculosis OR TB OR Pulmonary Tuberculosis OR Multi-Drug Resistant Tuberculosis OR MDR OR Extremely-Drug Resistant Tuberculosis or XDR)

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1 DATABASE Cochrane Database of Systematic Reviews DATE 15 DECEMBER 2015 #1 Safety of Crucell Ad35/ AERAS-402 OR Effectiveness of Crucell Ad35/ Aeras-402 OR Safety of MVA85A/ Aeras-485 OR Effectiveness of MVA85A/ Aeras-485 efficacy of Bacterial vectored vaccine for Tuberculosis OR efficacy of Viral vectored vaccine for Tuberculosis OR effectiveness of MDR vaccine OR effectiveness of XDR Vaccine OR Safety of BCG vaccine OR safety of Bacillus Calmette Guérin vaccine OR effectiveness of BCG vaccine OR effectiveness of Bacillus Calmette Guérin vaccine OR efficacy of BCG vaccine OR efficacy Bacillus Calmette Guérin vaccine OR Safety of MC vaccine OR safety of Meningococcal vaccine OR effectiveness of MC vaccine OR effectiveness of Meningococcal vaccine OR efficacy of MC vaccine OR efficacy of Meningococcal vaccine OR Clinical Trial for tuberculosis vaccine #4 (Tuberculosis OR TB OR Pulmonary Tuberculosis OR Multi-Drug Resistant Tuberculosis OR MDR OR Extremely-Drug Filters Time: ( )

2 DATABASE PDQ-Evidence DATE 16 December 2015 #1 Safety of Crucell Ad35/ AERAS-402 OR Effectiveness of Crucell Ad35/ Aeras-402 OR Safety of MVA85A/ Areas-485 OR Effectiveness of MVA85A/ Aeras-485 efficacy of Bacterial vectored vaccine for Tuberculosis OR efficacy of Viral vectored vaccine for Tuberculosis OR effectiveness of MDR vaccine OR effectiveness of XDR Vaccine OR Safety of BCG vaccine OR safety of Bacillus Calmette Guérin vaccine OR effectiveness of BCG vaccine OR effectiveness of Bacillus Calmette Guérin vaccine OR efficacy of BCG vaccine OR efficacy Bacillus Calmette Guérin vaccine OR Safety of MC vaccine OR safety of Meningococcal vaccine OR effectiveness of MC vaccine OR effectiveness of Meningococcal vaccine OR efficacy of MC vaccine OR efficacy of Meningococcal vaccine OR Clinical Trial for tuberculosis vaccine #3 #1 AND #2 #4 (Tuberculosis OR TB OR Pulmonary Tuberculosis OR Multi-Drug Resistant Tuberculosis OR MDR OR Extremely-Drug #5 #3 AND #4 FILTERS Publication Year: Added to Database: All Publication Type: All Pubmed Central (PMC): All Study Design: RCT Country where study was conducted: Afghanistan, Armenia, Azerbaijan, Bangladesh, Belarus, Brazil, Bulgaria, Cambodia, Chile, China, Congo, Democratic Republic, Croatia, Estonia, Ethiopia, Georgia, Ghana, Greece, Guinea, India, Indonesia, Kazakhstan, Kenya, Kyrgyzstan, Latvia, Lithuania, Moldova, Mozambique, Myanmar, Nigeria, Pakistan, Philippines, Russian Federation, South Africa, Tajikistan, Tanzania, Thailand, Uganda, Ukraine, Uzbekistan, Vietnam, Zimbabwe

3 DATABASE PUBMED #1 Safety of Crucell Ad35/ AERAS-402 OR Effectiveness of Crucell Ad35/ Aeras-402 OR Safety of MVA85A/ Areas-485 OR Effectiveness of MVA85A/ Aeras-485 efficacy of Bacterial vectored vaccine for Tuberculosis OR efficacy of Viral vectored vaccine for Tuberculosis OR effectiveness of MDR vaccine OR effectiveness of XDR Vaccine OR Safety of BCG vaccine OR safety of Bacillus Calmette Guérin vaccine OR effectiveness of BCG vaccine OR effectiveness of Bacillus Calmette Guérin vaccine OR efficacy of BCG vaccine OR efficacy Bacillus Calmette Guérin vaccine OR Safety of MC vaccine OR safety of Meningococcal vaccine OR effectiveness of MC vaccine OR effectiveness of Meningococcal vaccine OR efficacy of MC vaccine OR efficacy of Meningococcal vaccine OR Clinical Trial for tuberculosis vaccine #4 Tuberculosis OR TB OR Pulmonary Tuberculosis OR Multi-Drug Resistant Tuberculosis OR MDR OR Extremely-Drug FILTERS Article Types: Clinical Trials Text Availability: Abstract Publication Dates: 2013/01/ /12/16 Species: Humans

4 effectiveness of MDR vaccine OR effectiveness of XDR Vaccine OR Safety of BCG vaccine OR safety of Bacillus Calmette Guérin vaccine effectiveness of BCG vaccine OR effectiveness of Bacillus Calmette Guérin vaccine OR efficacy of BCG vaccine OR efficacy Bacillus Calm "312039,271205,271074,287205,283153,272254,312061,283159,287292,283375,313012,311859,271323,283286,272991,272411","M Douglas, and Bennett's Principles and...,vaccine,the Lancet,Manson's Tropical Infectious Diseases...,Vaccines (Sixth Edition),The Lanc Infectious Diseases,The New Public Health (Third Edition),Hunter's Tropical Medicine and Emerging Infecti...,Reference Module in Biom Edition),Advanced Drug Delivery Reviews,Clinical Immunology (Fourth Edition),International Journal of Infectious Diseases,Tuberculos DATABASE Science Direct #1 Safety of Crucell Ad35/ AERAS-402 OR Effectiveness of Crucell Ad35/ Aeras-402 OR Safety of MVA85A/ Areas-485 OR Effectiveness of MVA85A/ Aeras-485 efficacy of Bacterial vectored vaccine for Tuberculosis OR efficacy of Viral vectored vaccine for Tuberculosis OR Guérin vaccine OR Safety of MC vaccine OR safety of Meningococcal vaccine OR effectiveness of MC vaccine OR effectiveness of Meningococcal vaccine OR efficacy of MC vaccine OR efficacy of Meningococcal vaccine OR Clinical Trial for tuberculosis vaccine #4 (Tuberculosis vaccine OR TB vaccine OR Pulmonary Tuberculosis OR Multi-Drug Resistant Tuberculosis OR MDR OR Extremely-Drug Re Tuberculosis or XDR) FILTERS LIMIT-TO(yearnav, "2016,2015,2014,2013") AND LIMIT-TO(cids, Sciences,The Lancet Respiratory Medicine,Murray and Nadel's Textbook of Respiratory Medi...,Mucosal Immunology (Fourth

5 DATABASE TRIP Database STRATEGY PICO search P Infants, adolescents and adults I Tuberculosis vaccines, TB vaccines C BCG Vaccine, bacille Calmette-guerin vaccine O Immunity, immunogenicity from Tuberculosis FILTERS Controlled Trials,

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