Avian Influenza Clinical Picture, Risk profile & Treatment
|
|
- Leon Banks
- 5 years ago
- Views:
Transcription
1 Avian Influenza Clinical Picture, Risk profile & Treatment Jantjie Taljaard Adult ID Unit Tygerberg Academic Hospital University of Stellenbosch
2 CLINICAL PICTURE The clinical spectrum of influenza A (H5N1) in humans is based on descriptions of hospitalised patients The frequency of milder illnesses, subclinical infections and atypical presentations have not been determined, but case reports indicate that each occurs
3 N Engl J Med March 18; 350(12):
4 CLINICAL PICTURE Incubation period For classic human influenza viruses 2 to 3 days (range 1 7 days) For human influenza A (H5N1) Currently uncertain but may be longer The case-to-case intervals in household clusters have generally been 2-5 days.
5 CLINICAL PICTURE Symptoms High fever (> 38 o C) and an influenza like illness Lower respiratory tract symptoms like cough and shortness of breath are the usual initial presenting features Muscle pains, Malaise, Sore throat Watery diarrhoea without blood or inflammatory changes Although uncommon, may be more common than in classic influenza A and may precede respiratory symptoms with up to one week Other less common initial symptoms include: Vomiting, abdominal pain, pleuritic pain, bleeding from nose and gums and encephalopathy
6 CLINICAL PICTURE Physical examination Most patients are previously healthy young children and adults. May be tachypnoeic May have inspiratory crackles present Sputum production is variable (may even be bloody)
7 CLINICAL PICTURE Chest X-ray changes Almost all patients have clinical apparent pneumonia and CXR changes include: Diffuse, multifocal or patchy infiltrates Interstitial infiltrates Segmental or lobular consolidation with air bronchograms Radiographic changes are present on average 7 days after the onset of symptoms
8 N Engl J Med March 18;350(12):
9 N Engl J Med Jan 27;352(4):333-40
10 CLINICAL PICTURE Common laboratory findings Lymphopenia (<1 x 109/litre) and Thrombocytopenia at time of admission may be poor prognostic signs Moderately raised aminotransferase levels may also occur
11 CLINICAL PICTURE Clinical course Rapidly progression to respiratory distress (ARDS) and subsequent respiratory failure usually within 1 week of the onset of symptoms Multiorgan failure are common including: renal failure cardiac compromise (dilatation and/or supraventricular tachyarrhythmias)
12 CLINICAL PICTURE Mortality On average 9-10 days after onset of symptoms Most patients die due to respiratory failure High mortality rate in hospitalised patients (± 50%) despite adequate ventilation Mortality rate in those younger than 15 years in Thailand was 89%!
13 CASE DETECTION Early recognition of cases is confounded by: - non-specificity of the initial symptoms - high background rates of acute respiratory illnesses from other causes Detailed contact and travel histories and knowledge of viral activity in poultry are therefore essential!
14 Scenario 1: HPAI viruses have NOT been identified as a cause of illness in human or animal populations in South Africa Symptomatic: - Fever of 38oC and one or more lower respiratory tract symptoms: Cough, shortness of breath, difficulty in breathing and
15 During the 7 days before the onset of symptoms one or more of the following: - Close contact with an ill traveler from an area with Influenza A (H5N1) activity - A history of travel to a country or area with reported Influenza A (H5N1) activity in the animal populations - Living in an area in which there are rumors of deaths of domestic fowl and
16 High risk exposure/contact with one or more of the following: - contact (within 1 meter) with live or dead domestic fowl or wild birds in any setting - exposure to settings in which domestic fowl had been confined in the previous 6 weeks - contact (within touching or speaking distance) with a confirmed human case of Influenza A (H5N1) infection - contact (within touching or speaking distance) with a person with an unexplained acute respiratory illness that later resulted in death - occupational exposure
17 Scenario 2: HPAI viruses have been identified as a cause of illness in human or animal populations in South Africa Symptomatic: - Fever of 38oC and one or more lower respiratory tract symptoms: Cough, shortness of breath, difficulty in breathing and
18 High risk exposure/contact during the 7 days before the onset of symptoms with one or more of the following: - contact (within 1 meter) with live or dead domestic fowl or wild birds in any setting - exposure to settings in which domestic fowl had been confined in the previous 6 weeks - contact (within touching or speaking distance) with a confirmed human case of Influenza A (H5N1) infection - contact (within touching or speaking distance) with a person with an unexplained acute respiratory illness that later resulted in death - occupational exposure
19 CASE MANAGEMENT 1. Isolate all suspected/proven cases for: clinical monitoring diagnostic testing antiviral treatment (if available!) 2. Take respiratory and blood specimens for laboratory testing for influenza and other infections as clinically indicated 3. Treat with a neuraminidase inhibitor such as oseltamivir 75 mg orally, twice daily for 5 days as early in the clinical course as possible. Higher doses for longer periods may be needed for more severe infections.
20 Case management Hospitalise patients (if clinically indicated) Supportive care is the foundation of management Monitor oxygen saturation and treat desaturation with supplemental oxygen as required Most hospitalised patients required ventilation and ICU admission (for multiorgan failure/shock) within 48hrs after admission
21 Case management Hospitalise patients Nebulizers and high-air-flow oxygen masks have been implicated in nosocomial spread of SARS use only if clinically justified and apply them under strict airborne transmission precautions Take respiratory and blood specimens serially to check for possible bacterial co-infection consider empirical broad spectrum IV antibiotic therapy to prevent secondary bacterial infections
22
23 Case management Hospitalisation not required Educate patient and family on personal hygiene and infection control measures Instruct the patient to seek prompt medical care if the condition worsens Follow up by home visits or telephone contact (as resources permit)
24 Case management Discharge policy Adults: Studies are required to provide better understanding of viral excretion patterns in humans infected with the influenza A(H5N1) Until further evidence is available: WHO recommends that infection control precautions for adult patients remain in place for 7 days after resolution of fever.
25 Case management Children: Discharge policy Previous human influenza studies have indicated that children younger than 12 years can shed virus for 21 days after onset of illness. Therefore, infection control measures for children should ideally remain in place for this period. Where this is not feasible (because of a lack of local resources) Educate family on personal hygiene and infection control measures Children should not attend school during this period.
26 References BMJ - Vol 331; 5 November 2005; Douglas Fleming, Clinical Review: Influenza pandemics and avian flu 4. The Lancet Infectious Diseases - Vol 5; November 2005; Leonard A Mermel, Reflexion and Reaction: Pandemic avian influenza 5. NEJM - Vol 353; 29 September 2005; The Writing Committee of the WHO Consultation on Human Influenza A/H5, Current concepts: Avian Influenza A (H5N1) Infection in Humans
27 Thank you
H5N1 / Avian Influenza Essentials. Quick Reference for Providers and Public Health Officials
H5N1 / Avian Influenza Essentials Quick Reference for Providers and Public Health Officials December 2005 INFLUENZA Family: Orthomyxoviridae Genus: influenza virus Subtypes: A, B, and C Influenza A INFLUENZA
More informationSevere Acute Respiratory Syndrome ( SARS )
Severe Acute Respiratory Syndrome ( SARS ) Dr. Mohammad Rahim Kadivar Pediatrics Infections Specialist Shiraz University of Medical Sciences Slides Designer: Dr. Ramin Shafieian R. Dadrast What is SARS?
More informationAVIAN FLU BACKGROUND ABOUT THE CAUSE. 2. Is this a form of SARS? No. SARS is caused by a Coronavirus, not an influenza virus.
AVIAN FLU BACKGROUND 1. What is Avian Influenza? Is there only one type of avian flu? Avian influenza, or "bird flu", is a contagious disease of animals caused by Type A flu viruses that normally infect
More informationHuman infection with pandemic (H1N1) 2009 virus: updated interim WHO guidance on global surveillance
Human infection with pandemic (H1N1) 2009 virus: updated interim WHO guidance on global surveillance 10 July 2009 Background This document updates the interim WHO guidance on global surveillance of pandemic
More informationISPUB.COM. Bird flu: A Throbbing Stone In An Infectious Era. T Wadhwa, P Kumar Thirupathi EPIDEMIOLOGY TRANSMISSION FROM AVIAN TO HUMAN
ISPUB.COM The Internet Journal of Infectious Diseases Volume 7 Number 1 T Wadhwa, P Kumar Thirupathi Citation T Wadhwa, P Kumar Thirupathi.. The Internet Journal of Infectious Diseases. 2008 Volume 7 Number
More informationPUBLIC HEALTH SIGNIFICANCE SEASONAL INFLUENZA AVIAN INFLUENZA SWINE INFLUENZA
INFLUENZA DEFINITION Influenza is an acute highly infectious viral disease characterized by fever, general and respiratory tract catarrhal manifestations. Influenza has 3 Types Seasonal Influenza Avian
More informationNOVEL INFLUENZA A (H1N1) Swine Flu
Introduction Definitions Influenza-like Illness Emergency Department Assessment Anitiviral Medication Oseltamivir (Tamiflu) Dosing Infection Control Issues Staff Exposure References Introduction This guideline
More informationClinical Features of the Initial Cases of 2009 Pandemic Influenza A (H1N1) virus infection in China
Clinical Features of the Initial Cases of 2009 Pandemic Influenza A (H1N1) virus infection in China Naim Mahroum, MD Internal Medicine B Sheba Medical Center NEJM December 24, 2009 H1N1 Pandemic April
More informationSwine Influenza Update #3. Triage, Assessment, and Care of Patients Presenting with Respiratory Symptoms
Updated 12:00 p.m. April 30, 2009 Swine Influenza Update #3 Introduction: This document revises our last update which was sent April 28 th, 2009. The most important revisions include the following: 1.
More informationWHO Technical Consultation on the severity of disease caused by the new influenza A (H1N1) virus infections
WHO Technical Consultation on the severity of disease caused by the new influenza A (H1N1) virus infections Original short summary posted 6 May 2009. Revised full report posted May 9 2009. On 5 May 2009
More informationRalph KY Lee Honorary Secretary HKIOEH
HKIOEH Round Table: Updates on Human Swine Influenza Facts and Strategies on Disease Control & Prevention in Occupational Hygiene Perspectives 9 July 2009 Ralph KY Lee Honorary Secretary HKIOEH 1 Influenza
More informationAvian Influenza: Armageddon or Hype? Bryan E. Bledsoe, DO, FACEP The George Washington University Medical Center
Avian Influenza: Armageddon or Hype? Bryan E. Bledsoe, DO, FACEP The George Washington University Medical Center Definitions: Epidemic The occurrence of cases of an illness in a community or region which
More informationA. No. There are no current reports of avian influenza (bird flu) in birds in the U.S.
Bird Flu FAQ 2 Frequently Asked Avian Influenza Questions Avian influenza in birds Q. What is avian influenza? A. Avian influenza is an infectious disease of birds caused by type A strains of the influenza
More informationLecture Notes. Chapter 16: Bacterial Pneumonia
Lecture Notes Chapter 16: Bacterial Pneumonia Objectives Explain the epidemiology Identify the common causes Explain the pathological changes in the lung Identify clinical features Explain the treatment
More informationFlu Facts. January 2019
Flu Facts January 2019 Seasonal influenza is an acute respiratory infection caused by influenza viruses which circulate in all parts of the world. There are 4 types of seasonal influenza viruses, types
More informationEpiglottitis. Bronchitis. Bronchiolitis. Pneumonia. Croup syndrome. Miss. kamlah 2
Miss. kamlah 1 Epiglottitis. Bronchitis. Bronchiolitis. Pneumonia. Croup syndrome. Miss. kamlah 2 Acute Epiglottitis Is an infection of the epiglottis, the long narrow structure that closes off the glottis
More informationU.S. Human Cases of Swine Flu Infection (As of April 29, 2009, 11:00 AM ET)
Swine Flu Call Center Script 4/29/2009 3:00 PM SWINE FLU QUESTIONS What is swine flu? Swine Influenza, also called swine flu, is a respiratory disease of pigs caused by type A influenza viruses. Outbreaks
More informationInfluenza. Giovanni Maciocia
Influenza Giovanni Maciocia Zhang Zhong Jing (about 150-219AD) Ye Tian Shi (1667-1746) Wu Ju Tong (1758-1836) 1. WESTERN MEDICINE VIEW a) INFLUENZA INFLUENZA IN CHINESE MEDICINE Epidemiologists predict
More informationHuman Infection with Novel Influenza A Virus Case Report Form
Human Infection with Novel Influenza A Virus Case Report Form Form Approved OMB No. 0920-0004 Exp. Date 6/30/2013 Reporter Information State: Date reported to state/local health department: / / (MM/DD/YYYY)
More informationHealth Board Logo. Post SARS Outbreak Surveillance. Report of possible or probable cases (Form version 1) February 11 th 2004
Post SARS Outbreak Surveillance Report of possible or probable cases (Form version 1) February 11 th 2004 This form is to be used for persons who fit the surveillance case definition of possible or probable
More informationPandemic Influenza: Global and Philippine Situation
Pandemic Influenza: Global and Philippine Situation Beatriz Puzon-Quiambao, MD, FPPS, FPIDSP Research Institute for Tropical Medicine 17 th Annual PIDSP Convention, February 3-4, 2010 Chronology of Events
More informationINFLUENZA VIRUS. INFLUENZA VIRUS CDC WEBSITE
INFLUENZA VIRUS INFLUENZA VIRUS CDC WEBSITE http://www.cdc.gov/ncidod/diseases/flu/fluinfo.htm 1 THE IMPACT OF INFLUENZA Deaths: PANDEMICS 1918-19 S p a n is h flu 5 0 0,0 0 0 U S 2 0,0 0 0,0 0 0 w o rld
More informationSituation Update Pandemic (H1N1) August 2009
Situation Update Pandemic (H1N1) 2009 31 August 2009 Timeline pandemic (H1N1) 2009 April 12: an outbreak of influenza-like illness in Veracruz, Mexico reported to WHO April 15-17: two cases of the new
More informationSupplementary Appendix
Supplementary Appendix This appendix has been provided by the authors to give readers additional information about their work. Supplement to: Jain S, Kamimoto L, Bramley AM, et al. Hospitalized patients
More informationPeterborough County-City Health Unit Pandemic Influenza Plan Section 1: Background
1. Background Every expert on influenza agrees that the ability of the influenza virus to re-assort genes means that another influenza pandemic not only can happen, it almost certainly will happen Influenza
More informationA Virus is a very small organism which can only be viewed under the electron microscope.
Pandemic Influenza Fact Sheet What is a Virus? A Virus is a very small organism which can only be viewed under the electron microscope. Properties of viruses Although they are very small, they are live
More informationWolfgang Preiser. H5N1 in human beings and other influenza viruses of this season. Wolfgang Preiser. H5N1 avian influenza: Timeline of major events
H5N1 avian influenza: Timeline of major events "One Health" Avian Influenza Lunchtime Seminar Friday 19 August 2011 H5N1 in human beings and other influenza viruses of this season Wolfgang Preiser Division
More informationCDC Health Advisory 04/29/2009
H1N1 (Swine Flu) is a sub-type of Influenza A. Wexford Labs disinfectants are effective against Influenza A. Current CDC Recommendations for Environmental Control in the Healthcare Setting: CDC Health
More informationHow many students at St. Francis Preparatory School in New York City have become ill or been confirmed with swine flu?
Swine Flu Call Center Script SWINE FLU QUESTIONS What is swine flu? Swine Influenza, also called swine flu, is a respiratory disease of pigs caused by type A influenza viruses. Outbreaks of swine flu happen
More informationInfluenza: The Threat of a Pandemic
April, 2009 Definitions Epidemic: An increase in disease above what you what would normally expect. Pandemic: A worldwide epidemic 2 What is Influenza? Also called Flu, it is a contagious respiratory illness
More informationHealth care workers (HCWs) caring for suspected (clinically diagnosed) or confirmed cases of. Influenza A(H1N1)v FREQUENTLY ASKED QUESTIONS
Health care workers (HCWs) caring for suspected (clinically diagnosed) or confirmed cases of Questions found here: FREQUENTLY ASKED QUESTIONS What is pandemic flu? What is the difference between seasonal
More informationINTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION a Society that includes Basic Science, the Failing Heart, and Advanced Lung Disease
International Society of Heart and Lung Transplantation Advisory Statement on the Implications of Pandemic Influenza for Thoracic Organ Transplantation This advisory statement has been produced by the
More informationThe Demographic Impact of an Avian Flu Pandemic
The Demographic Impact of an Avian Flu Pandemic Emile Stipp 13 May 27 Overview Based on paper authored also by Dr Glenn Staples, Cassie Hamman and Jaco van der Merwe Influenza overview Avian Influenza
More informationINFLUENZA-2 Avian Influenza
INFLUENZA-2 Avian Influenza VL 7 Dec. 9 th 2013 Mohammed El-Khateeb Overview 1. Background Information 2. Origin/History 3. Brief overview of genome structure 4. Geographical Distribution 5. Pandemic Nature
More informationAmerican Academy of Pediatrics Section on Telehealth Care
American Academy of Pediatrics Section on Telehealth Care Educational Information for Telephone Triage Nurses Educational Information for Telephone Triage Nurses Volume 6 Number 2 April 2009 Editor Andrew
More informationInfluenza. Paul K. S. Chan Department of Microbiology The Chinese University of Hong Kong
Influenza Paul K. S. Chan Department of Microbiology The Chinese University of Hong Kong Influenza Virus Nomenclature Influenza virus A, B & C Influenza A : Haemagglutinin (H), neuraminidase (N) A H3N2,
More informationModule 1 : Influenza - what is it and how do you get it?
Module 1 : Influenza - what is it and how do you get it? Responsible/facilitators General Objective Specific Objectives Methodology Agency medical coordinator Understand the mechanism how influenza is
More informationSevere Acute Respiratory Infection (SARI) Guidelines. Chief Public Health Office Department of Health & Wellness
Severe Acute Respiratory Infection (SARI) Guidelines Chief Public Health Office Department of Health & Wellness 2013 The following document was prepared by the SARI Working Group. Maureen Anderson, Public
More informationSPECTRUM OF DISEASE. Rogelio Perez-Padilla MD National Institute of Respiratory Diseases, Mexico
SPECTRUM OF DISEASE INFLUENZA A H1N1 Rogelio Perez-Padilla MD National Institute of Respiratory Diseases, Mexico DEATHS ARDS PNEUMONIA ILI (fever) Use of health services Respiratory infections (mild) Self-care
More informationSeasonal Influenza in Pregnancy and Puerperium Guideline (GL1086)
Seasonal Influenza in Pregnancy and Puerperium Guideline (GL1086) Approval Approval Group Job Title, Chair of Committee Date Maternity & Children s Services Clinical Governance Committee Chair, Maternity
More informationSwine Flu Update and FAQ
Swine Flu Update and FAQ There have now been almost 6000 laboratory proven cases of A/H1N1 in the UK and the numbers are increasing rapidly on a daily basis. The published figure will significantly underestimate
More informationClinical Guidance for 2009 H1N1 Influenza and Seasonal Influenza. Barbara Wallace, MD New York State Department of Health (Updated 10/8/09)
Clinical Guidance for 2009 H1N1 Influenza and Seasonal Influenza Barbara Wallace, MD New York State Department of Health (Updated 10/8/09) 1 Outline Clinical assessment Diagnostic testing Antiviral medications
More informationHot Topic: H1N1 Flu (Swine Flu)
Hot Topic: H1N1 Flu (Swine Flu) For additional information go to: http://www.cdc.gov/ swineflu/general_info.htm Note: The information in this document is based on information from the CDC. The CDC site
More informationBC MHOs, PHNLs, ICPs, ERDOCs, IDSPEC, MEDMICRO, AMBULANCE, BCCDC Internal Groups, National Surveillance Network Partners
To: Subject: Purpose: Action required: Recommendations: BC MHOs, PHNLs, ICPs, ERDOCs, IDSPEC, MEDMICRO, AMBULANCE, BCCDC Internal Groups, National Surveillance Network Partners November 1, 2013 Emerging
More informationدکتر بهروز نقیلی استاد بیماریهای عفونی مرکس تحقیقات بیماریهای عفونی و گرمسیری پاییس 88
دکتر بهروز نقیلی استاد بیماریهای عفونی مرکس تحقیقات بیماریهای عفونی و گرمسیری پاییس 88 FLU.. How often can you escape? Three viral types are distinguished by their matrix and nucleoproteins Type Host Clinical
More informationRespiratory Viruses Policy
Respiratory Viruses Policy Page 1 of 8 Document Control Sheet Name of document: Version: 3 Status: Owner: File location / Filename: Respiratory viruses policy Date of this version: February 2013 Infection
More informationINFLUENZA. Rob Young (James. J. Reid) Faculty of Medicine University of Auckland (Otago)
INFLUENZA Rob Young (James. J. Reid) Faculty of Medicine University of Auckland (Otago) INFLUENZA Don t confuse with the common cold Symptoms may be similar BUT those with influenza are sick those with
More informationInfant and Pediatric Influenza. Mike Czervinske RRT-NPS University of Kansas Medical Center
Infant and Pediatric Influenza Mike Czervinske RRT-NPS University of Kansas Medical Center Influenza Infants and Influenza Acute infection of the respiratory tract Nose Throat Possibly lungs Pathophysiology
More informationFREQUENTLY ASKED QUESTIONS 1 Avian Influenza in Birds
FREQUENTLY ASKED QUESTIONS 1 Avian Influenza in Birds What is Avian Influenza? The disease commonly referred to as bird flu is an animal infection caused by the H5N1 virus. The virus occurs naturally among
More informationRunning head: INFLUENZA VIRUS SEASON PREPAREDNESS AND RESPONSE 1
Running head: INFLUENZA VIRUS SEASON PREPAREDNESS AND RESPONSE 1 Electron micrograph of H1N1 Virus (CDC, 2009) Influenza Virus Season Preparedness and Response Patricia Bolivar Walden University Epidemiology
More informationInfluenza. Dr Bhakti Vasant Public Health Physician Metro South Public Health Unit. Metro South Public Health Unit
Metro South Public Health Unit Influenza Dr Bhakti Vasant Public Health Physician Metro South Public Health Unit Source of image: CDC. Influenza images. Available from URL: https://www.cdc.gov/flu/images/h1
More informationAvian Influenza (Bird Flu) Fact Sheet
What is an avian influenza A (H5N1) virus? Influenza A (H5N1) virus also called H5N1 virus is an influenza A virus subtype that occurs mainly in birds. It was first isolated from birds (terns) in South
More informationClinical Diagnosis of Influenza in Adults. Andrew T. Pavia University of Utah
Clinical Diagnosis of Influenza in Adults Andrew T. Pavia University of Utah Context of the discussion Illness due to influenza is difficult to distinguish from other infections Antiviral agents are most
More information2009 (Pandemic) H1N1 Influenza Virus
2009 (Pandemic) H1N1 Influenza Virus September 15, 2009 Olympia, Washington Anthony A Marfin Washington State Department of Health Goals Understand current situation & pattern of transmission of 2009 H1N1
More informationNovel H1N1 Influenza. It s the flu after all! William Muth M.D. Samaritan Health Services 9 November 2009
Novel H1N1 Influenza It s the flu after all! William Muth M.D. Samaritan Health Services 9 November 2009 Influenza A Primer.. What is the flu? How do you get it? What s a virus anyhow? Can the flu be prevented,
More informationEmerging respiratory infections: MERS and beyond. Victoria Johnston Hospital for Tropical Diseases
Emerging respiratory infections: MERS and beyond Victoria Johnston Hospital for Tropical Diseases victoria.johnston@lshtm.ac.uk Emerging infections What are emerging infections? New infection Known infection:
More information(and what you can do about them)
(and what you can do about them) What s an outbreak? In general, more cases than expected (baseline) More cases clustered in a specific unit or facility than you d expect at a particular time of year Some
More informationTABLE OF CONTENTS. Peterborough County-City Health Unit Pandemic Influenza Plan Section 1: Introduction
TABLE OF CONTENTS 1. Introduction...1-2 1.1 Background...1-2 1.2 Why Does Peterborough County and City Need a Plan for Influenza Pandemic?...1-2 1.3 About Influenza...1-3 1.4 When Does Influenza Become
More informationPandemic Influenza A Matter of Time
Pandemic Influenza A Matter of Time A Community Education Package Package developed by: Mary Smith Grampians Region Infection Control Consultant Department of Human Services What is Seasonal Influenza?
More informationThe Triple Axel: Influenza, TB and MERS-CoV. Carolyn Pim, MD December 10, 2015
The Triple Axel: Influenza, TB and MERS-CoV Carolyn Pim, MD December 10, 2015 1. Influenza 2 Influenza 10-20% of the population is infected each year (up to 30% of children) Infection rates are highest
More informationQ: If antibody to the NA and HA are protective, why do we continually get epidemics & pandemics of flu?
Influenza virus Influenza virus Orthomyxoviridae family of viruses RNA enveloped viruses that make up three genera Influenzavirus A Influenzavirus B Influenzavirus C The type A viruses are the most virulent
More informationA Just in Time Primer on H1N1 Influenza A and Pandemic Influenza developed by the National Association of State EMS Officials and Revised by the
A Just in Time Primer on H1N1 Influenza A and Pandemic Influenza developed by the National Association of State EMS Officials and Revised by the Michigan Department of Community Health EMS and Trauma Systems
More informationInfluenza at the human-animal interface
Influenza at the human-animal interface Summary and assessment, 17 January to 14 February 2017 New infections 1 : Since the previous update, new human infections with influenza A(H7N9) and A(H1N1)v viruses
More informationCase Study. Case Study. Case Study. Objectives H1N1 Influenza: What You Need to Know. How are seasonal, pandemic and avian flu different?
2009 H1N1 Influenza: What You Need to Know Jan E. Patterson, MD, FACP, FIDSA Educating for Quality Improvement & Patient Safety Case Study April 19, 2009 33 yo pregnant female presented with 3 days of
More informationInfluenza and the Flu Shot Facts for Health Care Workers
Influenza and the Flu Shot Facts for Health Care Workers 2014-2015 Presentation to (group name) Your Name Your Title Date Influenza Facts o Highly contagious and common respiratory illness caused by influenza
More informationInfluenza. Paul K. S. Chan Department of Microbiology The Chinese University of Hong Kong
Influenza Paul K. S. Chan Department of Microbiology The Chinese University of Hong Kong Classification & Nomenclature Influenza virus A, B & C Influenza A : Haemagglutinin (H 1-16), neuraminidase (N1-9)
More informationAntivirals for Avian Influenza Outbreaks
Antivirals for Avian Influenza Outbreaks Issues in Influenza Pandemic Preparedness 1. Surveillance for pandemic preparedness eg. H5N1 2. Public health intervention eg. efficacy, feasibility and impact
More informationInfluenza Exposure Medical Response Guidance for the University of Wisconsin-Madison
Influenza Exposure Medical Response Guidance for the University of Wisconsin-Madison 1.0 Instructions: Information in this guidance is meant to inform both laboratory staff and health professionals about
More informationSEA/CD/154 Distribution : General. Avian Influenza in South-East Asia Region: Priority Areas for Research
SEA/CD/154 Distribution : General Avian Influenza in South-East Asia Region: Priority Areas for Research World Health Organization Publications of the World Health Organization enjoy copyright protection
More informationPublic Health: what is it?
Public Health: what is it? Joseph JY Sung MD, PhD School of Public Health Chinese University of Hong Kong Center for Emerging Infectious Diseases Common Symptoms of SARS 100 90 Mean incubation period
More informationPandemic and Avian Influenza Bird flu and Beyond. Jonathan Weinstein, MD FAAP
Jonathan Weinstein, MD FAAP Discussion points Pandemic Influenza The flu defined what is pandemic influenza? Influenza A in birds Infection in humans The current outbreak Potential for pandemic Infection
More information2009 / 2010 H1N1 FAQs
The information contained within this document was compiled from sources that include the Center for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services, and the Oregon Department
More informationH1N1 Influenza. Influenza-A Basics. Influenza Basics. April 1, History of Influenza Pandemics. April 1 September 25, 2009
April 1, 2009 H1N1 Influenza Jeff Goad, Pharm.D., MPH Associate Professor of Clinical Pharmacy USC School of Pharmacy April 1 September 25, 2009 History of Influenza Pandemics 400 B.C. 1889 Russian Flu
More informationPandemic Influenza. Bradford H. Lee, MD Nevada State Health Officer. Public Health: Working for a Safer and Healthier Nevada
Pandemic Influenza Bradford H. Lee, MD Nevada State Health Officer EXHIBIT C Legislative Committee on Health Care Document consists of 29 slides. Entire document provided. Due to size limitations, pages
More informationINFLUENZA SURVEILLANCE AND RESPONSE PROTOCOL
INFLUENZA SURVEILLANCE AND RESPONSE PROTOCOL Note: The situation surrounding pandemic and avian influenza is rapidly changing and this protocol will be revised as the situation evolves. Please make certain
More informationEmerging Respiratory Infections NZ Amanda McNaughton Respiratory Physician CCDHB Wellington
Emerging Respiratory Infections NZ 2015 Amanda McNaughton Respiratory Physician CCDHB Wellington Respiratory Infection: overview Influenza virus Clinical picture Emerging infection New Zealand Influenza
More informationQueen Sirikit National Institute of Child Health 9 August 2006
By Queen Sirikit National Institute of Child Health 9 August 2006 Influenza Virus Family Orthomyxoviridae Genus Influenzavirus A, B, C Avian influenza H1 16 N1 9 All highly pathogenic avian influenza
More informationAvian Influenza A (H7N9): Clinical Management. KW Choi Associate Consultant IDCTC, HA/ ICB, CHP
Avian Influenza A (H7N9): Clinical Management KW Choi Associate Consultant IDCTC, HA/ ICB, CHP Initial symptoms: nonspecific, similar to most other causes of ILI, CAP High index of suspicion and alertness
More informationGuideline for Students and Staff at Post-Secondary Institutions and Private Vocational Training Providers
Pandemic (H1N1) 2009 Revised 09 29 2009 Guideline for Students and Staff at Post-Secondary Institutions and Private Vocational Training Providers Prevention and Management of Student Exposure to Pandemic
More informationRESPIRATORY TRACT INFECTIONS. CLS 212: Medical Microbiology Zeina Alkudmani
RESPIRATORY TRACT INFECTIONS CLS 212: Medical Microbiology Zeina Alkudmani Lower Respiratory Tract Upper Respiratory Tract Anatomy of the Respiratory System Nasopharynx Oropharynx Respiratory Tract Infections
More informationINFLUENZA (Outbreaks; hospitalized or fatal pediatric cases)
INFLUENZA (Outbreaks; hospitalized or fatal pediatric cases) 1. Agent: Influenza viruses A, B, and C. Only influenza A and B are of public health concern since they are responsible for epidemics. 2. Identification:
More informationConflict of Interest and Disclosures. Research funding from GSK, Biofire
Pandemic Influenza Suchitra Rao, MBBS, Assistant Professor, Pediatric Infectious Diseases, Hospital Medicine and Epidemiology Global Health and Disasters Course, 2018 Conflict of Interest and Disclosures
More informationTHIS ACTIVITY HAS EXPIRED. CME CREDIT IS NO LONGER AVAILABLE
THIS ACTIVITY HAS EXPIRED. CME CREDIT IS NO LONGER AVAILABLE The following content is provided for informational purposes only. PREVENTION AND CONTROL OF INFLUENZA Lisa McHugh, MPH Influenza can be a serious
More informationCongregate Care Facilities
Congregate Care Facilities Information for Pierce County Long-Term Care Facilities vember 2017 Influenza Outbreak Guidelines Reporting Requirements Communicable Disease Division 3629 South D Street, Tacoma,
More informationThe Cold, the Flu or INFLUENZA!
The Cold, the Flu or INFLUENZA! Jim Reid Dept of General Practice and Rural Health Dunedin School of Medicine University of Otago INFLUENZA Don t confuse with the common cold Symptoms may be similar BUT
More informationInfluenza Infection In Human. Dr. Zuhaida A. Jalil Surveillance Sector Disease Control Division, MOH Malaysia 3 May 2018
Influenza Infection In Human Dr. Zuhaida A. Jalil Surveillance Sector Disease Control Division, MOH Malaysia 3 May 2018 Objective of the session: After completing this session, you will be able to: Understand
More informationHuman Cases of Swine Influenza in California, Kansas, New York City, Ohio, Texas, and Mexico Key Points April 26, 2009
1 Today, CDC confirmed additional human cases of swine influenza A (H1N1) virus infection in the United States, bringing the total number of U.S. confirmed cases to 21. This includes cases in California,
More informationAntimicrobial Stewardship in Community Acquired Pneumonia
Antimicrobial Stewardship in Community Acquired Pneumonia Medicine Review Course 2018 Dr Lee Tau Hong Consultant Department of Infectious Diseases National Centre for Infectious Diseases Scope 1. Diagnosis
More informationPneumonia. Trachea , The Patient Education Institute, Inc. id Last reviewed: 11/11/2017 1
Pneumonia Introduction Pneumonia is an inflammation and infection of the lungs. Pneumonia causes millions of deaths every year. It can affect anybody, but is more dangerous to older adults, babies and
More informationMERS H7N9. coronavirus. influenza virus. MERS: Since September 2012: 160 cases, including 68 deaths (42%)
MERS coronavirus H7N9 influenza virus Marc Van Ranst, KU Leuven MERS: Since September 2012: 160 cases, including 68 deaths (42%) MERS coronavirus patient, 83 years, Saudi-Arabia H7N9: Since February 2013:
More informationInfluenza Pandemic Preparedness For US Hospitals
Influenza Pandemic Preparedness For US Hospitals CAPT HA C. TANG, DO US Public Health Service Adjunct Associate Clinical Professor of Dartmouth Medical School, Community/Family Medicine Dept. Deputy Chief
More informationInfluenza B viruses are not divided into subtypes, but can be further broken down into different strains.
Influenza General Information Influenza (the flu) is a highly transmissible respiratory illness caused by influenza viruses. It can cause mild to severe illness, and may lead to death. Older people, young
More informationFREQUENTLY ASKED QUESTIONS SWINE FLU
FREQUENTLY ASKED QUESTIONS SWINE FLU Updated 5/6/09 ER FAQ What is swine flu? Swine flu is common disease of pigs and is caused by the same category of influenza virus (influenza A) that causes flu in
More informationViruses: Select Agents and Emerging Pathogens. Patricia Bolívar MS., CLS, PHM
Viruses: Select Agents and Emerging Pathogens Patricia Bolívar MS., CLS, PHM Objectives Review Select Agent Viruses. Key features to recognize Smallpox virus Update on emerging Viruses of possible pandemic
More informationMicrobiology Laboratory Directors, Infection Preventionists, Primary Care Providers, Emergency Department Directors, Infectious Disease Physicians
MEMORANDUM DATE: October 1, 2009 TO: FROM: SUBJECT: Microbiology Laboratory Directors, Infection Preventionists, Primary Care Providers, Emergency Department Directors, Infectious Disease Physicians Michael
More informationNovel H1N1 Influenza A: Protecting the Public
Novel H1N1 Influenza A: Protecting the Public Humayun J. Chaudhry, DO, MS, SM, FACOI, FACP, FAODME President, American College of Osteopathic Internists; Clinical Associate Professor of Preventive Medicine,
More informationDiagnosing and managing
www.bpac.org.nz keyword: influenza influenza Diagnosing and managing Key reviewers: Associate Professor Mark Thomas, Infectious Disease Specialist, School of Medical Sciences, University of Auckland Dr
More informationGeneral Medical Concerns
General Medical Concerns General Medical Concerns Fred Reifsteck MD Head Team Physician University of Georgia Missed Time: school, work, practice, games Decreased Performance Physical/ Mental stress: New
More informationIncidence of Seasonal Influenza
What Is All the Fuss? A Just-in in-time Primer on H1N1 Influenza A and Pandemic Influenza provided by the National Association of State EMS Officials May 1, 2009 Disclaimer This self-learning learning
More information