Index. 2-(a-Hydroxybenzyl)-benzimidazole (HBB),143 Hypotonicity,

Transcription

1 Index N-Acetyl-D-glucosamine,240 Actinomycin D, 39, 86, 116, 314 Adsorption of bacteriophage, on F pili, 36 of picornavirus, 119 of reovirus, Alfalfa mosaic virus, 66, 78, 90 top a, 73, 88 Alphavirus, 172 Arbovirus, see Togavirus Assembly of bacteriophage, models, 38 of plant virus, Bacillus stearothermophilus ribosome, II Bacillus subtilis ribosome, 26 Bacteria metabolism and bacteriophage infection, Bacteriophage RNA-containing, see RNA bacteriophage f2, 4-6, 9, 14, 19, 20 fr, 19 GA,19 MS2, 5, 12-16, 18, 19 M12,4 Q{j,4-9, 12-16, 19,20,29-31,34,81 3R,19 R17, 4-9,12-19 Barley stripe mosaic virus, 64, 78 Binding site, ribosomal, Bluetongue virus, 243, 248, , 263, Bovine enterovirus, 120, 124 Broadbean mottle virus, Bromalein, 176 Brome mosaic virus, 63, 72, 73, 78, 81-83,86-88,90-93 Bromovirus, 66 Budding of togavirus, 191, Capsid, empty, 142 Cardiovirus, 109, 120 Carlavirus, 64 Carnation latent virus, 64 Cauliflower mosaic virus, 63, 66 Cell culture of plant tissue, 62 Chikungunya virus, 173, 181 Chloramphenicol, 86 p-chloromercuribenzoate, 240 Cholesterol, viral, 187, 188 Chrysanthemum stunt disease, 71 Cistron of coat protein, of maturation protein, of polymerase protein, II, Citrus exocortis disease, 71 viroid,63 Coat protein, 12 cistron, properties, repression, repressor role, synthesis, initiation of, 25 Comovirus, 65

2 336 Index Complementation, 33-35, ,305 Cordycepin, 144 Cowpea mosaic virus, 65, 78, 85, 86, 90, 91 Cross reaction, 282 of unfolded protein, 9 Cucumber mosaic virus, 81 Cycloheximide, 143,314 Cytopathology, Cytoplasmic polyhedrosis virus (CPV), , ,254,256, 258, , , ,318 Dengue virus, 173, 175, 181 Deoxyribonucleic acid, see DNA Detergent, 177 2,6-Diaminopurine, 145 Diphtheria toxin, 144 Dithiothreitol, 176 DNA cellular, viral, , D-particle of orbivirus, 247, 249, Eastern equine encephalitis virus, 173 Eclipse of bacteriophage, 37 Encephalomyocarditis virus, 120, 133 Enterovirus, 109 Ethidium bromide, 145,314 Exocytosis, 193 Fatty acids, viral, Fiji disease virus, 238, 243, 251, 255, 319 Flavovirus, 172,B-Fluorophenylalanine (FPA), Fluorouracil,40, 145 Foot-and-mouth disease virus, 123, 150,B-Galactosidase, 41 Gliotoxin, 145,B-Glucosidase, 240 Glycoprotein, viral, , Guanidine, Growth curve, viral, , Hemagglutination, Herpes simplex virus, 122 Hybridization, RNA-RNA, (a-Hydroxybenzyl)-benzimidazole (HBB),143 Hypotonicity, Infection of plant tissue by viruses, by abrasion, 70 early events, efficiency, 70 Interference, 122, Interferon, induced by double-stranded RNA, 122 Japanese encephalitis virus, 173, 176, 186, 214,218 Kunjin virus, 173 Lettuce necrotic yellow virus, Lipase, 176 Lipids viral, L-particle of orbivirus, 247, 249, of RNA bacteriophage, 3 Maize rough dwarf virus, 238, 243, ,265,319 Maturation protein cistron, properties, Mengovirus, 124 N-Methyl-isatin-,B-4':4 ' dibutylthiosemicarbazone, 145 Morphogenesis, Murray Valley encephalitis virus, 181 Nepovirus, 65 Nucleocapsid, 183, Nucleotide sequence, 154 rate of addition, Oat sterile dwarf virus, 238 Oligonucleotide, , Orbivirus, , 236, 241, 247, ,256,263 D-particle, 247, 249, L-particle, 247, 249, polypeptide, replication, RNA, 258, 263

3 Index 337 Orbivirus (cont.) transcriptase, 277 Orthoreovirus, see Reovirus Pactamycin, 127, 144 Pangola stunt virus, 238 Particle, defective-interfering, 153, Pea enation mosaic virus, 66, 91 Penetration of bacteriophage, of picornavirus, 120 Periodate, 240 PFU, see Plaque-forming unit Phenethyl alcohol, 144 Phospholipase, 176 Phospholipids, viral, , 199 Picornavirus adsorption, 119 capsid, empty, 113 cardiovirus, 109 and cells, , chemistry, complementation, defective-interfering particle, 153 discoveries, RNA polymerase, 110 replicative form of RNA, 111 translation of polycistronic gene product, 111. elution, 120 enterovirus, 109 environmental factors, genetics, history, homology in nucleotide sequence, 154 hybridization of RNA-RNA, 154 hypotonicity, infection, early events, infectivity of RNA, inhibition of DNA synthesis, of protein of host cell, of RNA synthesis, interference, maturation, 118 membrane, role of, morphogenesis, multiplication inhibited, Picornavirus (cont.) mutant, 147 agents, 148 temperature-sensitive, particle, defective-interfering (01), 153 penetration, 120 recombination, genetic, reproduction, rescue phenomenon, 151 rhinovirus, 109 sedimentation coefficient, 113 specificity, 121 structure, synthesis of protein, of viral RNA, terminology, 109 Pilus, 36 Plant reoviruses, see Reoviruses Plant RNA viruses, Plaque-forming unit (PFU), 115, Polarity of translation, Poliovirus interference, 122 length of RNA, 114 purified, 114 RNA, length of, 114 type I, L Sc 2ab, 149 Polymerase, see RNA polymerase Polyribosome, Potato spindle tuber disease, 71 viroid,63 Potato virus X, 64 Potato virus Y, 64 Potato yellow dwarf virus, 63, 64 Potexvirus, 64 Potyvirus, 64 Procapsid, see Capsid, empty Proflavine, 145 Protein, viral, , kinetics, polypeptide, , 185,213 synthesis, translation, in vitro, Protomer, immature, 142 Puromycin, 143, 144,206,314 Pyronine, 145 Raspberry ringspot virus, 91

4 338 Index Reoviridae capsid polypeptides, capsomers, classification, cytoplasmic polyhedrosis virus, 234 orbivirus, 233 orthoreovirus, 233 core polypeptides, discovery of double-stranded RNA, 231 morphogenesis, morphology, nature of virion, 235 nucleotide addition, rate of, occurrence, properties, 243 reproduction, RNA, nature of, spikes, , 252 stability against physical agents, 256 transcriptase, , 285, 287 transcription, Reovirus, , , 256, ,274,278, adsorption, capsid polypeptides, cell, DNA synthesis, protein synthesis, complementation, 305 DNA synthesis by cell, enumeration of particles, formation of RNA, genome of ten segments, 305 growth cycle, one-step, hemagglutination, inhibitors, interferon, messenger RNA, ten species of, 297 transcription, translation, morphology, mutant of Fields and Joklik, of genome segment deletion, 311 of Ikegami and Gomatos, 310 temperature-sensitive, oligonucleotides, , particle enumeration, of plants, 234, , , ,274,278, Reovirus (cont.) plaque formation, protein synthesis of cell, purification, replication, RNA, formation, messenger, transcriptase, transcription of mrna, in vitro, in vivo, translation of mrna, in vitro, in vivo, uncoating, uptake, Replicase, see RNA polymerase Replication of viral nucleic acid, 71-86, Replication complex, 116, 119, 132 Replicative form (RF), see RNA replicative form Replicative intermediate (RI), Repression, 16 Reproduction of picornavirus, of reoviridae, of RNA bacteriophage, I-59 of RNA plant virus, of togavirus, Rescue phenomenon, 151 RF, see RNA replicative form Rhinovirus, 109 RI, see Replicative intermediate ~ j b o n u c4, l 180 e a s e, Ribosome of Bacillus stearothermophilus, II, 26 of Bacillus subtilis, 26 binding site, of Escherichia coli, 26 specificity, 26 Rice dwarf virus, 238, 243, 251, 255, 258, 265,319 Rifampicin, 38 RNA bacteriophage adsorption, assembly, coat protein, 19 complementary strand, 33-35

5 Index 339 RNA bacteriophage (cont.) discovery, I eclipse, 37 genes, 2 genome structure primary, 25 secondary, 25 and host metabolism, L-particle, 3 minus strand, 8 nascent RNA, particles, 2-3 penetration, plus strand, 8 properties, 2-20 release from cell, 38 replication, in vitro, 29 in vivo, replicative form, 28, replicative intermediate, 28, reproduction, I-59 strand, complementary, minus, 8 plus, 8 structure, primary, 4-5 secondary, 18 tertiary, 18 synthesis, and host metabolism, ' -terminus, ' -terminus, 5-7 translation, RNA ligase, 140 RNA, messenger, , RNA plant viruses, see individual viruses assembly, classification, genome of virus, host-virus system, infection, early events, properties, replication of viral nucleic acid, mechanism, site of, in vitro, in vivo, replicate form (RF), replicate intermediate (RI), 78 RNA plant viruses (cont.) reproduction, RNA, low molecular weight (LMC), RNA properties, translation of viral nucleic acid, control mechanism, in infected tissues, transmission, types, virus-host system, RNA polymerase, RNA-dependent, 4, 20,23,29,81-84, , , ,285,287 cistron, 11,15,16 host cell factors, inhibition, 123 of orbivirus, 277 protein, 13,20 Q(3, 29-31, 34, 81 repression, 16 translation, 27 RNA replicative form (RF), 77-78, III, RNA replicative intermediate (RI), 28, 201 RNA, viral, interjacent, , 208, 209 messenger, synthesis, replication mechanism, time course, 131 Satellite tobacco necrosis virus, 65, 72, 74 Satellite tobacco ringspot virus, 65, 72 Scrapie, 63 Semliki forest virus, 173, 181, 188, 192, 193,196,198 Sindbis virus, 173, 174, , 192, 196, 197,211 Sparsomycin, 144 Spikes, , 252 st. Louis encephalitis virus, 173, 181, Thiouracil,95 Tobacco mosaic virus (TMV), 61, 64, 72, 77,79,80-88,93 Tobacco necrosis virus, 87 Tobacco rattle virus, 64, 72, 89, 95 RNA, long, 75

6 340 Index Tobacco rattle virus (cant.) satellite, 73 short, 74 Tobacco ringspot virus, 65, 72, 78, 81 Tobacco streak virus, 91; see also Satellite tobacco viruses Tobravirus, see Tobacco rattle virus Togavirus budding, 191, carbohydrates, 184 cholesterol, 187, 188 composition, chemical, by electron microscopy, 173, 174 cytopathology, density, 174 effect of enzyme on, 176 exocytosis, 193 fatty acids, genetics, glycoprotein, , glycosylation, 212 group A, 173 group B, 173 growth curve, infection of cell, lipids, messenger RNA, viral, morphogenesis, mutant, temperature-sensitive, 197 nucleocapsid, 183, particle, defective-interfering, phospholipids, , 199 polymerase, viral RNA, polypeptide, 185,213 properties, , 183 protein, viral, , purification, replication, reproduction, Togavirus (cant.) RNA, viral, , messenger, transcription, sedimentation coefficient, 177 ~ r u c t u r ~ symmetry, 177 terminology, , 183 transcription, of viral RNA, Tomato bushy stunt virus, 65 Tomato spotted wilt virus, 63, 66 Tombusvirus, 65 Transcriptase, see RNA polymerase Transcription, , Translation, control, 27 of mrna, polarity, of protein, regulation, 20-22, 25 of viral nucleic acid, in vitro, 24 Transmission of plant viruses, Trypsin, 176 Turnip yellow mosaic virus, 65, 77, 79, 81-83,86,94,95 Tymovirus, 65 Uncoating, Venezuelan equine encephalitis virus, 173 Vesicular stomatitis virus, 122 Viroid, 63, 72 RNA, Virus, see individual viruses Western equine encephalitis virus, 173, 181 Wound tumor virus (WTV), 63, 65, ,243, , ,256,258,264,265,319