A New Era in SFC Column Technology
|
|
- Vivien Berry
- 6 years ago
- Views:
Transcription
1 B TM
2 A ew Era in SFC Column Technology Combining state-of-the-art media manufacturing with the industry leading column technology, Viridis Supercritical Fluid Chromatography (SFC) columns bring a new level of reproducibility to the world of laboratory scale purification. Viridis SFC columns are now available for analytical and preparative chromatography as: Viridis SFC -Ethylpyridine columns Viridis SFC Silica columns TM A
3 Viridis SFC columns, manufactured for reliability and consistency Based upon over 50 years of experience in the separation science industry, Waters chromatographic media sets the standard for quality and batch-tobatch reproducibility. As a primary manufacturer of silica and hybrid chromatographic particles, all stages of product synthesis are meticulously monitored and controlled, ensuring complete characterization of the finished product. This level of manufacturing process understanding delivers chromatographic media with guaranteed consistent performance year after year. Wate rs Fine C hemi cal M an u fa ctu ring Plant in Taunton, Massachusetts, USA. Waters is committed to support the purification scientists who use SFC technology. With the acquisition of TharSFC and the development of Viridis SFC columns, Waters Corporation now offers a complete SFC solution that encompasses system, service, software and new columns. SFC-MS Prep 100
4 Viridis SFC Columns Manufactured with BD Technology Column Performance Identifying the Problem Laboratory-scale SFC purification presents many challenges to the chromatographer. Inconsistency in column-to-column performance and lifetimes often result in lost samples, repeat purification runs and poor scalability from small to larger volume columns. Common SFC prep column failures are due to mechanical instabilities, especially voids in the packed bed. The patented BD technology 1 combines optimized packing processes with a unique set of column designs ensuring increased lifetime and better reproducibility. When a column is used in a SFC system, it must remain stable during operations. The bed must be packed sufficiently dense to withstand the compressive fluid forces encountered during use. In the case of analytical column dimensions, the necessary packed bed density can be generally achieved using traditional slurry packing methods. As the diameter of the column increases, it becomes increasingly difficult to reach the bed density required for stable, long term performance, especially when using small particles. The optimum bed density is dependent upon the specific properties of the chromatographic particles and column dimensions. BD ptimized Bed Density High-pressure Slurry Packing Localized Bed Expansion ear Inlet BD Process ptimum Bed Density Throughout Axial-ram Slurry Packing Localized Compression ear Inlet ptimized Bed Density is achieved by applying pre-determined axial force only at the column inlet. 1 US Patent # 7,99,410; UK Patent # GB BD Column Design Improved Mechanical Stability Waters combines high-pressure slurry packing with a carefully calculated axial compression element localized at the less-dense inlet end of the bed. With careful tuning of the packing process for each particle type and column geometry, the Prep BD design and process results in predictable, uniform density profiles throughout the column. Established procedures ensure that the column bed is not over-compressed or disrupted during the final column packing process. Excess axial compression applied at the inlet can break particles, build bridges, and lower local bed permeability. Exploded Prep BD Column Hardware For purification, the Viridis SFC columns incorporate chemically inert seals made to prevent leaks and a pair of specially designed filter housings with frits and distributors built to withstand high pressures.
5 Viridis SFC -Ethylpyridine Columns -Ethylpyridine chemistry is successfully used for a wide range of achiral SFC applications due to its retention, peak shape and selectivity properties. Viridis SFC -Ethylpyridine columns also provide high reliability and reproducibility and can be used for analytical and preparative applications. Si -Ethylpyridine Ligand Excellent Peak Shape Viridis SFC -Ethylpyridine columns exhibit good peak shape whether separations are performed with or without additives such as diethylamine or ammonium acetate. High Mass Loading Viridis SFC -Ethylpyridine columns provide excellent mass loading to ensure maximum throughput. Conditions Conditions Viridis SFC -Ethylpyridine Column, 4.6 x 150 mm, 5 µm Part umber: Gradient Separation: 10 min Flow Rate:.5 ml/min at 40 C Wavelength: 54 nm System Back Pressure: 100 bar Injection Volume: µl Compounds 1 Caffeine Amitriptyline Thymine 4 Cytosine 5 Sulfamethoxazole 6 Sulfamethizole Viridis SFC -Ethylpyridine BD Column, 19 x 150 mm, 5 µm Part umber: Gradient Separation: 4. min Mobile Phase: 5-15% methanol with no additive Flow Rate: 85 g/min at 40 C Wavelength: 0 nm System Back Pressure: 10 bar Compounds 1 Coumarin Flavone Ibuprofen 4 Carbamazepine Mobile Phase: 5-40% methanol with no additive Injection Volume: 100 µl Sample Concentration: 80 mg/ml Total Mass Load: 8 mg Absorbance (mau) Absorbance (mau) Mobile Phase: 5-40% methanol with 0.% diethylamine (DEA) Injection Volume: 50 µl Sample Concentration: 80 mg/ml Total Mass Load: 8 mg -50 Absorbance (mau) Mobile Phase: 5-40% methanol with 0 mm ammonium acetate min Injection Volume: 750 µl Sample Concentration: 80 mg/ml Total Mass Load: 60 mg min 4
6 Viridis SFC Silica Columns Based on Waters long history of chromatographic silica production, the Viridis SFC Silica columns are designed to be highly reproducible and predictable based on tight product specifications and very low metal content. Selectivity Viridis SFC Silica columns offer added selectivity due to the highly polar, unbonded surface and will have greater interaction with polar functional groups when compared to Viridis SFC -Ethylpyridine columns. Viridis SFC Silica column versus Viridis SFC -Ethylpyridine column Conditions Gradient Separation: 4. min Mobile Phase: 5-15% methanol with no additive Flow Rate: 85 g/min at 40 C Wavelength: 0 nm System Back Pressure: 10 bar Compounds 1 Flavone Ibuprofen Carbamazepine 1 6.0e-1 4.0e-1.0e-1 Viridis SFC Silica BD Column, 19 x 150 mm, 5 µm Part umber: e-1 1.0e-1 6.0e e-1.0e-1 Viridis SFC -Ethylpyridine BD Column, 19 x 150 mm, 5 µm Part umber: e-1 1.0e min Using the same SFC gradient conditions, different selectivity can be achieved by using a Viridis SFC -Ethylpyridine column or Viridis SFC silica column. The retention time for ibuprofen was reduced and the carbamazepine retention time was increased by switching SFC column chemistries, with little change in the retention of flavone. 5
7 RDERIG IFRMATI Chemistry Particle Shape Particle Size (µm) Pore Size (Å) Surface Area (m /g) Pore Volume (cc/g) Carbon Load (%) Endcapped -Ethylpyridine Spherical no Silica Spherical n/a n/a Description Part umber Viridis SFC -Ethylpyridine columns Viridis SFC -Ethylpyridine Column, 4.6 x 50 mm, 5 µm Viridis SFC -Ethylpyridine Column, 4.6 x 100 mm, 5 µm Viridis SFC -Ethylpyridine Column, 4.6 x 150 mm, 5 µm Viridis SFC -Ethylpyridine Column, 4.6 x 50 mm, 5 µm Viridis SFC -Ethylpyridine Column, 10 x 50 mm, 5 µm Viridis SFC -Ethylpyridine Column, 10 x 100 mm, 5 µm Viridis SFC -Ethylpyridine Column, 10 x 150 mm, 5 µm Viridis SFC -Ethylpyridine Column, 10 x 50 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 19 x 50 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 19 x 100 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 19 x 150 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 19 x 50 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 0 x 50 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 0 x 75 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 0 x 100 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 0 x 150 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 0 x 50 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 50 x 50 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 50 x 100 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 50 x 150 mm, 5 µm Viridis SFC -Ethylpyridine BD Column, 50 x 50 mm, 5 µm Description Part umber Viridis SFC Silica columns Viridis SFC Silica Column, 4.6 x 50 mm, 5 µm Viridis SFC Silica Column, 4.6 x 100 mm, 5 µm Viridis SFC Silica Column, 4.6 x 150 mm, 5 µm Viridis SFC Silica Column, 4.6 x 50 mm, 5 µm Viridis SFC Silica Column, 10 x 50 mm, 5 µm Viridis SFC Silica Column, 10 x 100 mm, 5 µm Viridis SFC Silica Column, 10 x 150 mm, 5 µm Viridis SFC Silica Column, 10 x 50 mm, 5 µm Viridis SFC Silica BD Column, 19 x 50 mm, 5 µm Viridis SFC Silica BD Column, 19 x 100 mm, 5 µm Viridis SFC Silica BD Column, 19 x 150 mm, 5 µm Viridis SFC Silica BD Column, 19 x 50 mm, 5 µm Viridis SFC Silica BD Column, 0 x 50 mm, 5 µm Viridis SFC Silica BD Column, 0 x 75 mm, 5 µm Viridis SFC Silica BD Column, 0 x 100 mm, 5 µm Viridis SFC Silica BD Column, 0 x 150 mm, 5 µm Viridis SFC Silica BD Column, 0 x 50 mm, 5 µm Viridis SFC Silica BD Column, 50 x 50 mm, 5 µm Viridis SFC Silica BD Column, 50 x 100 mm, 5 µm Viridis SFC Silica BD Column, 50 x 150 mm, 5 µm Viridis SFC Silica BD Column, 50 x 50 mm, 5 µm H H H Carbamazepine Caffeine H Cytosine Flavone Ibuprofen H S H S S H Coumarin Amitriptyline H Thymine H Sulfamethizole H Sulfamethoxazole 6
8 Sales ffices Austria and European Export (Central South Eastern Europe, CIS and Middle East) Australia Belgium Brazil Canada x05 China CIS/Russia / Czech Republic Denmark Finland France Germany Hong Kong The etherlands orway Poland Puerto Rico Singapore Spain Sweden Switzerland Taiwan United Kingdom All other countries: Waters Corporation U.S.A Hungary India and India Subcontinent Ireland Italy Japan Korea Mexico The quality management system of Waters manufacturing facilities in Taunton, Massachusetts and Wexford, Ireland complies with the International Standard IS 9001:000 Quality Management and Quality Assurance Standards. Waters quality management system is periodically audited by the registering body to ensure compliance. A 010 Waters Corporation. Waters, The Science of What s Possible, Viridis, BD and SFC-MS Prep 100 are trademarks of Waters Corporation E April 010 KK-FP
Improving Food Process Control Using the
Improving Food Process Control Using the UPLC Amino Acid Analysis Solution Hillary B. Hewitson, Thomas E. Wheat, Diane M. Diehl INTRODUCTION Food products have different desirability and value based in
More informationProviding a Universal, One-step Alternative to Liquid-Liquid Extraction in Bioanalysis
Providing a Universal, ne-step Alternative to Liquid-Liquid Extraction in Bioanalysis Jessalynn P. Wheaton, Erin E. Chambers, and Kenneth J. Fountain APPLICATIN BENEFITS n Simple, one-step sample preparation
More informationApplicationNOTE EXACT MASS MEASUREMENT OF ACTIVE COMPONENTS OF TRADITIONAL HERBAL MEDICINES BY ORTHOGONAL ACCELERATION TIME-OF-FLIGHT.
Objective The aim of the study presented is to determine the presence of target Gingkolides in Gingko biloba leaf extract. The data presented shows Gingkolides determined to be present in the extract analyzed.
More informationA New HILIC/RP Mixed-Mode Column and Its Applications in Surfactant Analysis
A New HILIC/RP Mixed-Mode Column and Its Applications in Surfactant Analysis X. Liu, C. Pohl, Dionex Corporation, Sunnyvale, CA, USA ABSTRACT Although reversed-phase (RP) silica columns (e.g., C18 and
More informationChemical compatibility of the Pall QPoint TM Docking Station - Tap Assembly with common surface disinfectants
Technical Report.78a Chemical compatibility of the Pall QPoint TM - Tap Assembly with common surface disinfectants QPoint - More than Filtration .0 Background The Pall QPoint Tap Water Filter Assembly
More informationImpurity Profiling of Carbamazepine by HPLC/UV
Application Note: 52049 Impurity Profiling of Carbamazepine by HPLC/UV Terry Zhang, Guifeng Jiang, Thermo Fisher Scientific, San Jose, CA, USA Key Words Accela Hypersil GOLD Carbamazepine Drug Analysis
More informationCore-Shell Technology for Proteins and Peptides
Core-Shell Technology for Proteins and Peptides Better BioSeparations on HPLC and UHPLC Systems www.phenomenex.com/aeris Aeris Core-Shell Technology Core-Shell Particles Precision Engineered for Protein
More informationPreparative Chromatography Meets UHPLC
Preparative Chromatography Meets UHPLC The Power of Kinetex Core-Shell Technology with the Performance of Piston Packed Prep Columns Ultra-High Efficiencies Ultra-Long Lifetimes NO Added Pressure Two Award
More informationAPPLICATIONS TN A Comparison of Various Kinetex C18 Phases USP: L1
APPLICATIONS A Comparison of Various Kinetex C18 Phases Zeshan Aqeel and Jeff Layne Phenomenex, Inc., 411 Madrid Ave., Torrance, CA 91 USA Introduction When performing reversed phase LC separations, there
More information[ Care and Use Manual ]
MALDI Calibration Kit I. Introduction The MALDI Calibration Kit is a conveniently packaged selection of MALDI matrices and calibration standards (includes high-purity Neg Ion Mode Calibrant for accurate
More informationHPLC. Varian Dynamax Preparative HPLC Columns
HPLC Varian Dynamax Preparative HPLC Columns Preparative HPLC Simple, successful and economical Linear scale-up move from analytical separation to preparative purification quickly and simply. Dynamic Axial
More informationPosterREPRINT INTRODUCTION. 2-D PAGE of Mouse Liver Samples. 2-D PAGE of E.coli Samples. Digestion / Cleanup. EXPERIMENTAL 1-D PAGE of BSA Samples
INTRODUCTION Identification and characterization of low abundance proteins separated by 2D gel electrophoresis is complicated by two important factors; the use of suitable staining techniques for the visualization
More informationBio-Rad Laboratories. Hemoglobin Testing. VARIANT II Hemoglobin Testing System For HbA 1c
Bio-Rad Laboratories Hemoglobin Testing VARIANT II Hemoglobin Testing System For HbA 1c Bio-Rad CDM System CDM 5.1 VII Instrument Patient Report V2_A1c_NU Patient Data Sample ID: AD Patient ID: Name: Physician:
More informationAnalytical and Preparative SFC Columns
Analytical and Preparative SFC Columns Best Performance for Supercritical Fluid Chromatography Sepax SFC-Cyano... Sepax SFC-Amino... Sepax SFC-Pyridine... Sepax SFC-SCX... 5 Sepax SFC-Diol... 6 Sepax SFC-Silica...
More informationApplicationNOTE A MULTI-RESIDUE LC/MS/MS METHOD FOR THE DETERMINATION OF 81 PESTICIDE RESIDUES IN FRUIT AND VEGETABLES: PART 1, METHOD OVERVIEW
ApplicationNOTE A MULTI-RESIDUE LC/MS/MS METHOD FOR THE DETERMINATION OF 81 PESTICIDE RESIDUES IN FRUIT AND VEGETABLES: PART 1, METHOD OVERVIEW Gordon Kearney1, Lutz Alder2, Anthony Newton1, Jeannette
More informationSIMPLIFIED CHIRAL SEPARATIONS. Lux Cellulose-1. Guaranteed Alternative. to CHIRALCEL OD-H. Exceptional Quality Sensibly Priced
SIMPLIFIED IRAL SEPARATIS Lux ellulose- Guaranteed Alternative to IRALEL D- Exceptional Quality Sensibly Priced Lux ellulose- ellulose tris(3,5-dimethylphenylcarbamate) This dimethyl cellulose selector
More informationEnantiomeric and Diastereoisomeric Resolutions of Chiral Triazole Fungicides using Lux Polysaccharide-Based Chiral Stationary Phases
T-1164 APPLICATIS Enantiomeric and Diastereoisomeric Resolutions of Chiral Triazole Fungicides using Lux Polysaccharide-Based Chiral Stationary Phases Marc Jacob, Liming Peng, Michael Klein, Tom eveland,
More informationACE. For increased polar retention and alternative selectivity. Alternative selectivity for method development
ACE C8-Amide For increased polar retention and alternative selectivity Alternative selectivity for method development Improved separations with polar, acidic, basic and phenolic compounds High efficiency
More informationYMC-Actus. Columns for Semi-preparative HPLC. Selectivity Durability Loadability
YMC-Actus Columns for Semi-preparative HPLC Selectivity Durability Loadability Fast semi-preparative chromatography Semi-preparative chromatography is the link between analytical HPLC and preparative LC.
More informationBio-Rad Laboratories HEMOGLOBIN Testing Bio-Rad A1c. VARIANT II TURBO Link. Fully-Automated HbA 1c Testing
Bio-Rad Laboratories HEMOGLOBIN Testing Bio-Rad A1c VARIANT II TURBO Link Fully-Automated HbA 1c Testing Bio-Rad Laboratories HEMOGLOBIN Testing VARIANT II TURBO Link Efficient streamlined process Powerful
More informationBio-Rad Laboratories HEMOGLOBIN Testing Bio-Rad A1c. VARIANT II TURBO Link System. Fully-Automated HbA 1c Testing
Bio-Rad Laboratories HEMOGLOBIN Testing Bio-Rad A1c VARIANT II TURBO Link System Fully-Automated HbA 1c Testing Bio-Rad Laboratories HEMOGLOBIN Testing VARIANT II TURBO Link System Efficient streamlined
More informationAPPLICATIONS TN µm Core-Shell Particle. (continued on page 2) Page 1 of 8. For additional technical notes, visit
Kinetex 5 µm Core-Shell Columns Deliver Significant Improvements in Chromatographic Efficiency and Resolution versus Traditional Fully Porous 5 µm Columns Philip J. Koerner and Jeff Layne Phenomenex, Inc.,
More informationHigh-Throughput, Cost-Efficient LC-MS/MS Forensic Method for Measuring Buprenorphine and Norbuprenorphine in Urine
High-Throughput, Cost-Efficient LC-MS/MS Forensic Method for Measuring and in Urine Xiaolei Xie, Joe DiBussolo, Marta Kozak; Thermo Fisher Scientific, San Jose, CA Application Note 627 Key Words, norbuprenorphine,
More informationBioPlex 2200 Infectious Disease Panels
BioPlex 2200 System BioPlex 2200 Infectious Disease Panels An Expanding Multiplexed Assay Menu Lyme HIV Ag-Ab MMV IgM Syphilis Total & RPR MMRV EBV HSV-1 & HSV-2 EBV IgM ToRC IgM ToRC Leading the way with
More informationThe first and only fully-automated, multiplexed solution for Measles, Mumps, Rubella and Varicella-zoster virus antibody testing
Bio-Rad Laboratories BioPlex 2200 System BioPlex 2200 MMRV IgG Kit The first and only fully-automated, multiplexed solution for Measles, Mumps, Rubella and Varicella-zoster virus antibody testing Bio-Rad
More informationGerry Hendrickx Regional Sales Manager Central Europe. Developments in Waters Column Chemistries : BEH Technology
Gerry Hendrickx Regional Sales Manager Central Europe Developments in Waters Column Chemistries : BEH Technology XTerra Columns: First Generation Hybrid Particles Initial Launch 1999 Advantages of XTerra
More informationIn-Use Evaluation Report
In-Use Evaluation Report 160127.3WIN Pall QPoint TM Shower Water Filter Assembly Reusable Docking Station - Shower Assembly (QDS) and Disposable Filter Capsule for up to 62 Day Use - Shower (QR212 and
More informationInertSustain Phenylhexyl. A New Second Choice Column to Change Chromatographic Behavior
InertSustain Phenylhexyl A ew Second Choice Column to Change Chromatographic Behavior Providing Alternative Selectivity to C8 Phases InertSustain Phenylhexyl columns are bonded with phenylhexyl groups,
More informationMercury Speciation Determinations in Asian Dietary Supplements
Mercury Speciation Determinations in Asian Dietary Supplements Terri Christison, Deepali Mohindra, Frank Hoefler, and Linda Lopez, Thermo Fisher Scientific, Sunnyvale, California, USA Overview Purpose:
More informationExceed your Purification Goals. Guaranteed. Phenomenex l WEB:
Exceed your Purification Goals Guaranteed The Axia Prep Column Advantage Extended column lifetime Reproducibility: column-to-column and batch-to-batch igher efficiency Improved peak shape Increased loadability
More informationProtect Your Mass Spec
Protect Your Mass Spec Sample Preparation Solutions for Biological Samples www.phenomenex.com/bioms Dirty Samples Could be Costing You Money and Sensitivity Biological samples contain a wide variety of
More informationHigh-Throughput Quantitative LC-MS/MS Analysis of 6 Opiates and 14 Benzodiazepines in Urine
High-Throughput Quantitative LC-MS/MS Analysis of and 14 Benzodiazepines in Urine Bill Yu, Kristine Van Natta, Marta Kozak, Thermo Fisher Scientific, San Jose, CA Application Note 588 Key Words Opiates,
More informationStax Disposable Depth Filters
USD 2758 Stax Disposable Depth Filters Featuring Seitz AKS Activated Carbon Media Highest Efficiency in Adsorption and Design Powdered activated carbon (PAC) is widely used in the pharmaceutical industry
More informationAgilent Technologies Prep LC Columns
Agilent Technologies Prep LC Columns Agilent Technologies Prep LC Columns Agilent Technologies has always taken seriously its responsibility to ensure your success. That s why all our instruments and supplies
More informationSepax Technologies, Inc.
Sepax Technologies, Inc. Sepax Technologies, Inc. develops and manufactures products in the area of chemical and biological separations, biosurfaces and proteomics. Sepax product portfolio includes ) liquid
More informationC30 ISOMERS HAVE MET THEIR MATCH
C30 ISOMERS HAVE MET THEIR MATCH INTRODUCING THE NEW! Built on proven Fused-Core particle technology, the is designed to deliver fast separations ideal for lipids and isomers compared to your C18. FEATURES
More informationInertSustainBio C18. Rapid Separations of Proteins and Peptides
InertSustainBio C18 Rapid Separations of Proteins and Peptides High Recoveries of Proteins and Peptides The 200A pore size silica creates the opportunity to separate compounds having a molecular weight
More informationAPPLICATIONS TN Overview of Kinetex 2.6 µm Core-Shell Technology
Determination of Impurities and Related Substances for Acetylsalicylic Acid (Ph. Eur. Monograph 9): Increased Sensitivity and Resolution, Faster Analysis, and Reduced Solvent Usage Using Kinetex 2.6 µm
More informationImproved Extraction and Analysis of Hexavalent Chromium from Soil and Water
Improved Extraction and Analysis of Hexavalent Chromium from Soil and Water Richard F. Jack, 1 Jinshui Che, 2 Lipika Basumallick, 1 and Jeffrey Rohrer 1 1 Thermo Fisher Scientific, Sunnyvale, CA, USA;
More informationPyroMark Q24 CpG MGMT Handbook
December 2009 PyroMark Q24 CpG MGMT Handbook For quantification of CpG methylation in region +17 to +39 in the MGMT gene Sample & Assay Technologies QIAGEN Sample and Assay Technologies QIAGEN is the leading
More informationColumns The FIRST and ONLY sub-2 µm core-shell columns on the market
Better UHPLC Performance Starts NW.7 µm Core-Shell * Columns The IRST and NLY sub- µm core-shell columns on the market Phenomenex India Laxmi Cyber City, Ground loor, B Block, Survey no: Kondapur, Hyderabad
More informationAPPLICATIONS Improving Intact Biogeneric Protein Separations with Aeris WIDEPORE Core-Shell Columns
Improving Intact Biogeneric Protein Separations with Aeris WIDEPORE Core-Shell Columns Michael McGinley, Deborah Jarrett, and Jeff Layne Phenomenex, Inc., 411 Madrid Avenue, Torrance, CA 91 USA Aeris WIDEPORE
More informationCardiac Assessment Controls
Bio-Rad Laboratories CARDIAC ASSESSMENT CONTROLS Cardiac Assessment Controls Value Assigned for Clinical Laboratory and Point of Care Test Systems Solving the Challenges of Troponin I Testing for the Central
More informationTGX and TGX Stain-Free FastCast Acrylamide Kits
Electrophoresis TGX and TGX Stain-Free FastCast Acrylamide Kits The newest frontier for handcast gels It s Time to Expect More from Handcast Gels! FastCast kits provide unparalleled convenience and performance.
More informationAeris. Precision Engineered Core- Shell Particles for Ultra-High Resolution BioSeparations. Aeris PEPTIDE. Aeris WIDEPORE
Aeris Precision Engineered Core- Shell Particles for Ultra-High Resolution BioSeparations Aeris is a specialized line of reversed phase core-shell UHPLC columns, built exclusively for the ultra-high performance
More informationAPPLICATIONS TN Determination of Sugars in Animal Feed using HPLC-ELSD
Determination of Sugars in Animal Feed using HPLC-ELSD Laura Snow, Zeshan Aqeel, Allen Misa and Scott Krepich Phenomenex, Inc., Madrid Ave., Torrance, CA 9050 USA Laura Snow Scientist- Phenologix Outside
More informationDetermination of Clinically Relevant Compounds using HPLC and Electrochemical Detection with a Boron-Doped Diamond Electrode
Deteration of Clinically Relevant Compounds using HPLC and Electrochemical Detection with a Boron-Doped Diamond Electrode Bruce Bailey, Marc Plante, David Thomas, Qi Zhang and Ian Acworth Thermo Fisher
More informationAPPLICATIONS TN Dramatically Improve Existing 5 µm and 3 µm Fully Porous Methods with Kinetex 5 µm Core-shell Technology.
Dramatically Improve Existing 5 µm and 3 µm Fully Porous Methods with Kinetex 5 µm Core-shell Technology Jeff Layne, Phenomenex, Inc. Phenomenex, Inc., 411 Madrid Ave., Torrance, CA 951 USA With virtually
More informationForensic and clinical products and services
r o i d s N a t u r a l p r o d u c t s T D M Forensic and clinical products and services R e f e r e n c e s t a n d a r d s F o r e n s i c a n d c l i n i c a l t o x i c o l o g y S t a b l e i s o
More informationPurification of Insulin with YMC-Triart Prep C8. Increased Output at Reduced Costs
Purification of Insulin with YMC-Triart Prep C8 Increased Output at Reduced Costs 2 Introduction YMC bulk material along with phases from Daiso and Kromasil took part in a study by a major peptide manufacturer.
More informationSolving One of Chromatography s Biggest Dilemmas Proper Sealing of Chromatography Autosampler Vials
Solving One of Chromatography s Biggest Dilemmas Proper Sealing of Chromatography Autosampler Vials D. Edwards 2, D. Lennartz 1, L.Shick 2 1 Thermo Fisher Scientific, Langerwehe, Germany 2 Thermo Fisher
More informationNobelProcera Implant Bar Overdenture complete range of fixed and removable solutions.
NobelProcera Implant Bar Overdenture EXPERIENCE THE NEW WORLD OF CAD/CAM DENTISTRY 2 NobelProcera Implant Bar Overdenture NobelProcera Implant Bar Overdenture complete range of fixed and removable solutions.
More informationSeQuant ZIC -HILIC For all who expect more...
SeQuant ZIC -ILIC For all who expect more... The better choice for PLC and LC/MS of all types of polar and hydrophilic compounds EMD Millipore Corp. is a subsidiary of Merck KGaA, Darmstadt, Germany Poor
More informationETB Data. there was. compared
AETA 2009 Survey Report Introduction Included in this report are survey data collected from the member embryo transfer business ss (ETB s) of the American Embryo Transfer Association for 2009. This report
More informationTerms and Conditions. VISA Global Customer Assistance Services
Terms and Conditions VISA Global Customer Assistance Services Visa Global Customer Assistance Services (VGCAS) 1 The Visa Global Customer Assistance Services are co-ordinated by the Global Assistance Centre
More informationGlobal EHS Resource Center
Global EHS Resource Center Understand environmental and workplace safety requirements that affect your global operations. 800.372.1033 bna.com/gelw Global EHS Resource Center This comprehensive research
More informationWELLNESS COACHING. Wellness & Personal Fitness Solution Providers
WELLNESS COACHING Wellness & Personal Fitness Solution Providers Introducing Ourselves... We are Personal Wellness Coaches 2 We help people look and feel better by: - Educating on proper nutrition (80%)
More informationGC-MS/MS Analysis of Benzodiazepines Using Analyte Protectants
GC-MS/MS Analysis of Benzodiazepines Using Analyte Protectants Jeremy Matthews, 1 Alex Chen, 2 and Flavio Bedini 1 1 Thermo Fisher Scientific, Singapore; 2 Alpha Analytical Pte Ltd, Singapore Overview
More informationHyper-fast & Super-rugged
Hyper-fast & Super-rugged UHPLC & HPLC columns FALL 2013 PRODUCT CATALOG Hyper-fast & Super-rugged UHPLC & HPLC columns he introduction of HALO columns, developed using innovative Fused-Core particle
More informationFigure 1. Core-Shell Particle Technology
Purification of Chlorogenic cid from Green Coffee using Kinetex Core-Shell Technology in xia Preparative Formats Zeshan qeel Technical Magician Zeeshan loves to collect watches and the ack to the Future
More informationA Fast, Accurate, and Sensitive Quantitiation of Vitamin C in Plasma by Impact Protein Precipitation and Kinetex 5 µm Core-Shell XB-C18 HPLC Columns
A Fast, Accurate, and Sensitive Quantitiation of Vitamin C in Plasma by Impact Protein Precipitation and Kinetex 5 µm Core-Shell XB-C18 HPLC Columns Shuguang Li, Sky Countryman, and Erica Pike Phenomenex,
More informationA Novel Solution for Vitamin K₁ and K₂ Analysis in Human Plasma by LC-MS/MS
A Novel Solution for Vitamin K₁ and K₂ Analysis in Human Plasma by LC-MS/MS By Shun-Hsin Liang and Frances Carroll Abstract Vitamin K₁ and K₂ analysis is typically complex and time-consuming because these
More informationBio-Rad Laboratories. Cardiac Assessment Controls. Value Assigned for Clinical Laboratory and Point of Care Test Systems
Bio-Rad Laboratories Cardiac Assessment Controls Cardiac Assessment Controls Value Assigned for Clinical Laboratory and Point of Care Test Systems Solving the Challenges of Troponin I Testing for the Central
More informationSeQuant ZIC -HILIC For all who expect more...
SeQuant ZIC -ILIC For all who expect more... The better choice for PLC and LC/MS of all types of polar and hydrophilic compounds EMD Millipore is a division of Merck KGaA, Darmstadt, Germany Poor retention
More informationILyte TM Automated electrolyte analyzers
ILyte TM Automated electrolyte analyzers The IL program for electrolyte analysis. Worry Free, Easy to Use Maintenance Free Electrodes ILyte Na +, K + analyzer ILyte Na +, K +, Cl - analyzer ILyte Na +,
More informationCardiac Assessment Controls A critical element of reliable cardiac testing
Cardiac Assessment Controls Cardiac Assessment Controls A critical element of reliable cardiac testing Choose the products best suited for your cardiac assessment needs Each year, 17.7 million people on
More informationThe high efficiency of sub-2 µm UHPLC columns combined with the low pressure and high speed of monolith columns.
The high efficiency of sub-2 µm UHPLC columns combined with the low pressure and high speed of monolith columns. Fast High peak capacity Low back pressure PROTEIN PEPTIDE UHPLC COLUMNS Put these new, high-performance
More informationAll about interrai. Len Gray Coordinator, interrai Network of Excellence in Acute Care April
All about interrai Len Gray Coordinator, interrai Network of Excellence in Acute Care April 2014 The interrai research collaborative Australia Belgium Canada Chile China Czech Republic Denmark Estonia
More informationImmunohematology. IH-QC Modular System. Select. Combine. Control.
Immunohematology IH-QC Modular System Select. Combine. Control. IH-QC Modular System Select. Combine. Control. Transfusion guidelines recommend regular checking of test materials, test methods, local working
More informationEurospher II the logical choice. Physical properties of Eurospher II silica gel: Silica gel: ultra pure, > % Metal content: < 10 ppm
HPLC SMB smometry Euroline Eurospher II Eurospher II the logical choice After more than years on the market, our Eurospher stationary phase has established a reputation for being a first-class packing
More informationInjection Techniques Questionnaire (ITQ) WorldWide Results Needle Gauge
Injection Techniques Questionnaire (ITQ) WorldWide Results 2014-2015 Needle Gauge BACKGROUND All needles are at least twice as long as the skin is thick More than twice as long 31G =.26mm Surface = 1
More informationNobelDesign 1.3 Installation guide
NobelDesign 1.3 Installation guide 2 NobelDesign 1.3 Installation guide // English Disclaimer of liability: This product is part of an overall concept and may only be used in conjunction with the associated
More informationRapid and Direct Analysis of Free Phytosterols by Reversed Phase HPLC with Electrochemical Detection
Rapid and Direct Analysis of Free Phytosterols by Reversed Phase HPLC with Electrochemical Detection Bruce Bailey, Marc Plante, David Thomas, Qi Zhang and Ian Acworth Thermo Fisher Scientific, Chelmsford,
More informationThird Party Controls for Your Dade Behring Systems
Bio-Rad Laboratories Q U A L I T Y C O N T R O L Third Party Controls for Your Dade Behring Systems The Complete QC Solution from Bio-Rad Laboratories Bio-Rad has the control you need for your Dade Behring
More informationNobelProcera Implant Bar Overdenture EXPERIENCE THE NEW WORLD OF CAD/CAM DENTISTRY
NobelProcera Implant Bar Overdenture EXPERIENCE THE NEW WORLD OF CAD/CAM DENTISTRY 2 NobelProcera Implant Bar Overdenture NobelProcera Implant Bar Overdenture complete range of fixed and removable solutions.
More informationOrdering Information. ProteOn XPR36 System. Protein Interaction Analysis
Protein Interaction Analysis Ordering Information ProteOn XPR36 System The ProteOn XPR36 system is an optical biosensor capable of simultaneously measuring 36 individual molecular interactions. It integrates
More informationPrep Columns. and Bulk Media. and Bulk Media
Prep Columns and Bulk Media Axia Columns...346-355 Process Chromatography...356-36 Bulk Media...356-36 Columns, Scout and Preparative...359-36 Sepra Bulk Sorbents... 36 Prep Columns and Bulk Media 345-36
More informationACE CN-ES. Extra Stability. Extended Spacer. Enhanced Selectivity ACE. Combining CN polar selectivity with enhanced hydrophobicity
ACE CN-ES Combining CN polar selectivity with enhanced hydrophobicity Extended Spacer Extra Stability New stationary phase technology for UHPLC and HPLC separations Alternative polar selectivity for method
More informationHER2 FISH pharmdx TM Interpretation Guide - Breast Cancer
P A T H O L O G Y HER2 FISH pharmdx TM Interpretation Guide - Breast Cancer For In Vitro Diagnostic Use FDA approved as an aid in the assessment of patients for whom Herceptin TM (trastuzumab) treatment
More informationPurification - Flash Chromatography
SuperFlash Compound Purification Columns Optimal Design Cost effective, high performance disposable flash column specifically designed for flash chromatography. Excellent Separations Designed to deliver
More informationHRM Series PCB Power Relays
Features: SPCO contacts. Sealed to allow washing after flow soldering. Specifications: Coil Data: Nominal Voltage Nominal Power consumption : 3V dc to 24V dc. : 540mW to 720mW. Contact Data: Contact Arrangement
More informationPharmaceutical, Medical and Health-related Government and Regulatory bodies around the world.
1 International International Conference on Harmonization (ICH) World Health Organization (WHO) 2 Argentina National Administration of Drugs, Food and medical Technology. Australia s Department of health
More informationLC-MS/MS Method for the Determination of Tenofovir from Plasma
LC-MS/MS Method for the Determination of Tenofovir from Plasma Kimberly Phipps, Thermo Fisher Scientific, Runcorn, Cheshire, UK Application Note 687 Key Words SPE, SOLA CX, Hypersil GOLD, tenofovir Abstract
More informationFor Far. Greater. UHPLC Column Performance You Must Have Kinetex Core-Shell UHPLC Columns.
For Far Greater UHPLC Column Performance... You Must Have Kinetex Core-Shell UHPLC Columns www.phenomenex.com/kinetex The UHPLC Core-Shell Advantage Kinetex Core-Shell Technology produces increased efficiencies
More informationHER103, HER107 Power Diodes - Fast Recovery
High Efficiency DO-41 Features: Fast reverse recovery time, t rr. Low forward voltage drop, V F. Low cost axial packages. High current capability. High reliability. High surge current capability. Mechanical
More informationDetermination of Water- and Fat-Soluble Vitamins in Nutritional Supplements by HPLC with UV Detection
Application Note 5 Determination of Water- and Fat- Vitamins in Nutritional Supplements by HPLC with UV Detection Introduction Vitamins are a well-known a group of compounds that are essential for human
More informationGlycanPac AXR-1 Columns
CHRMATGRAPHY GlycanPac AXR- Columns For High Resolution Glycan Analysis Product Specifications The Thermo Scientific GlycanPac AXR- columns are highperformance, silica-based HPLC columns for simultaneous
More informationFOURIER STUDY GREYLOCK PRESS: CTS PRODUCT SAMPLE - FOURIER YES. Did the study achieve its main objective?
FOURIER STUDY Did the study achieve its main objective? 2 15% 1 5% 9.8% YES FOURIER compared Repatha with placebo in patients who were taking a statin and had hardening or narrowing of the arteries and
More informationAchiral SFC: Development of an Orthogonal SFC Method for Mometasone Furoate Impurity Analysis
Achiral SFC: Development of an Orthogonal SFC Method for Mometasone Furoate Impurity Analysis Zhenyu Wang Merck Research Laboratories NJCG 2013 Outline SFC chronicle The journey of a half century Re-birth
More informationartus EBV QS-RGQ Kit Performance Characteristics May 2012 Sample & Assay Technologies Analytical sensitivity plasma
artus EBV QS-RGQ Kit Performance Characteristics artus EBV QS-RGQ Kit, Version 1, 4501363 Check availability of new electronic labeling revisions at www.qiagen.com/products/artusebvpcrkitce.aspx before
More informationPhenyl-Hexyl. UHPLC Columns. lternate, complementary selectivity to C18 and C8 bonded phases
Phenyl-Hexyl UHPLC Columns lternate, complementary selectivity to A C8 and C8 bonded phases articularly recommended for P compounds containing aromatic groups xcellent bonded phase stability for E durable,
More informationMENTAL HEALTH CARE. OECD HCQI Expert meeting 17 th of May, Rie Fujisawa
MENTAL HEALTH CARE OECD HCQI Expert meeting 17 th of May, 2013 Rie Fujisawa Mental health indicators Any hospital readmissions for patients with schizophrenia Same hospital readmissions for patients with
More information508 the number of suicide deaths in deaths per 100,000 people was the suicide rate in Suicide deaths in 2013 by gender
An overview of suicide statistics This document summarises information about suicide deaths in New Zealand covering up to 13. It does not attempt to explain causes of suicidal behaviour or causes of changes
More informationAm I getting the very best value from my UHPLC analyses?
Am I getting the very best value from my UHPLC analyses? Stephen Luke LC Columns Product Manager 1 Primary reasons for UHPLC use Very fast Very high resolution Column 2.1 x 50 mm Column 2.1 x 150 mm Run
More information3 Normal-Phase Columns. Reversed-Phase C18 Columns (ODS) Reversed-Phase Columns (Other than ODS) Columns for HTS and LC/MS Analysis.
We are pleased to present the 11th YMC General Catalog. Since its formation in 1980, YMC Co., Ltd. has been working in the rapidly changing field of chemistry. Over this time, the rate of discovery of
More information2012 Waters Corporation 1
An Introduction to Waters HPLC and ACQUITY UPLC Column Technologies for small molecule analysis Esa Lehtorinne Esa_Lehtorinne@waters.com Tel: +358-9-5659 5659 6288 Fax: +358-9-5659 5659 6282 Waters Finland
More informationRoc On with These Dependable LC Columns
Roc LC s Conventional column built to be the cornerstone for your lab; pressure rated for any 400 bar system. Solid and reliable delivers the peak shape, reproducibility, ruggedness, and performance you
More informationNitrogen/Protein Determination in Starch by Flash Combustion using Large Sample Weight as an Alternative to the Kjeldahl Method
Nitrogen/Protein Determination in Starch by Flash Combustion using Large Sample Weight as an Alternative to the Kjeldahl Method Liliana Krotz and Guido Giazzi Thermo Fisher Scientific, Milan, Italy Overview
More informationDetection and Quantification of Inorganic Arsenic in Fruit Juices by Capillary Ion Chromatography with Suppressed Conductivity Detection
Detection and Quantification of Inorganic Arsenic in Fruit Juices by Capillary Ion Chromatography with Suppressed Conductivity Detection Hua Yang, Linda Lopez Thermo Fisher Scientific, Sunnyvale, CA, USA
More information