Humanitarian Initiative to Prepare for a Pandemic Influenza Emergency (HIPPIE) Ron Waldman, MD Avian and Pandemic Influenza Unit USAID/Washington

Size: px
Start display at page:

Download "Humanitarian Initiative to Prepare for a Pandemic Influenza Emergency (HIPPIE) Ron Waldman, MD Avian and Pandemic Influenza Unit USAID/Washington"

Transcription

1 Humanitarian Initiative to Prepare for a Pandemic Influenza Emergency (HIPPIE) Ron Waldman, MD Avian and Pandemic Influenza Unit USAID/Washington

2

3

4 Objectives of Presentation Review current status of avian influenza (very briefly) Discuss why USAID should care What USAID proposes to do about it

5 What is the difference between an epidemic and a pandemic? Epidemics occur every year due to minor changes in influenza A viruses that circulate Pandemics happen only occasionally when a completely new influenza A virus circulates A really large worldwide epidemic Results in more severe illnesses and more deaths

6

7 How do yearly epidemics occur? Antigenic Drift Imperfect manufacturing of virus Small changes in H and N components due to random genetic mutations Can prevent the body s immune system from fully protecting against the virus, and re-infection can occur Reason for yearly flu vaccination Reason that 1 or 2 of the three virus strains in the vaccine are updated every year

8 Why does a pandemic occur? Antigenic shift Sudden change in the antigenic structure of microorganisms, especially viruses, which produces new strains new strains of the microorganism Hosts previously exposed to other strains have little or no acquired immunity to the new strain Antigenic shift is believed to be the explanation for the occurrence of strains of microorganisms, such as the influenza virus, associated with large scale epidemics. SHIFT HAPPENS

9

10 WHO Classification of Pandemic Phases WHO Pandemic Classification

11 Current Status of Avian and Human H5N1 Influenza

12 Source: OIE (and WHO) reports. * Bangladesh has not officially reported since May. ** No official data on Nigeria, except Jan 07 human case; assumed to be all months of 2007 since AI is endemic. *** Vietnam s outbreaks have run from Aug 06-Nov 07.? indicates that virus may still be circulating in these countries throughout 2007, despite the absence of official reports. Afghanistan15 Bangladesh14 Burma13 Cambodia12 China@ 11 Egypt@ 10 9 Indonesia@ 8 Kuwait 7 Nigeria@ 6 Pakistan 5 Russia 4 S. Korea 3 Thailand 2 Turkey 1 Vietnam 16 Four Countries with Nearly Continuous H5N1 Transmission from Aug 06-Oct 07 Only shown are countries with 20 or more poultry outbreaks since Dec 2003????? 0 J F M A M J J A S O N D J F M A M J J A S O N

13 Most Human Cases and Deaths Occur in Young People Cases (n=290) 7% Age 40+ Deaths (n=193) 7% Age % Age Age % 40% Age Age % Lab-confirmed H5N1 cases in humans reported to WHO between November 2003 and November 12, 2007 for which there is age data.

14 Most Human Cases Not Hospitalized In Time to Get Maximal Benefit from Tamiflu maximum Tamiflu efficacy mean = 4.6 days # human H5N1 cases and deaths % CFR 22% CFR 76% case fatality rate (CFR) Days between symptom onset and hospitalization = cases = deaths Lab-confirmed H5N1 cases in humans reported to WHO between November 2003 and November 12, 2007 for which there is symptom onset and health status data.

15

16

17 Total number of cases includes number of deaths. WHO reports only laboratory-confirmed cases. All dates refer to onset of illness. Cumulative Number of Confirmed Human Cases of Avian Influenza A/(H5N1) Reported to WHO 23 January 2008 Country Total cases deaths cases deaths cases deaths cases deaths cases deaths cases deaths cases deaths Azerbaijan Cambodia China Djibouti Egypt Indonesia Iraq Lao People's Dem Repc Myanmar Nigeria Pakistan Thailand Turkey Viet Nam Total

18 Top Three Reasons Why You Should Care Reason #3: It has happened before; there is no reason why it will not happen again. There is virtual unanimity in the scientific community that it is a pandemic is a question of when, not if: at a recent meeting, 90% of experts polled said there would be a pandemic within one generation, 15% within 3 years

19 What about past flu pandemics? Credi: US National Museum of Health and Medicine 1918: Spanish Flu 1957: Asian Flu 1968: Hong Kong Flu million deaths 575,000 US deaths 1-4 million deaths 70,000 US deaths 1-4 million deaths 34,000 US deaths Barbara Wallace, New York State Department of Health 2005

20 Cholera in Peru 7 th pandemic began in Indonesia in 1961 and spread to Asia, Europe, and Africa before arriving in LAC (for the first time in one hundred years) in 1991 In 1991, there were 400,000 cases, and 4,000 deaths in 16 countries in this Region In Peru alone, the macro-economic loss was $770 million from trade embargoes and the decline in tourism What was the economic impact at the household level?

21 What is required for a pandemic of influenza to occur? Novel virus to which population has little or no immunity Virus that is pathogenic and virulent in humans Virus must be capable of sustained person-to-person transmission

22 Top Three Reasons Why You Should Care Reason #2: The humanitarian consequences of a pandemic could be devastating in terms of lives lost, economic disaster, and societal upheaval.

23 Which is more important, preventing the next war or preventing the next influenza pandemic? Deaths (100,000s) Civil War WWI Spanish Flu WWII Korea Vietnam

24

25 Can pandemic influenza have the kind of impact that AIDS has had at its worst? Life expectancy-usa,

26 Top Three Reasons Why You Should Care Reason #1: You can do something about it!!

27 Can a pandemic be prevented?

28 Many epidemiologists feel that early detection, early response, or surveillance and containment, à la smallpox eradication, can work Computer models suggest that it might be possible with aggressive antiviral use (where the pandemic strain emerges, assuming that the strain is sensitive). Conditions include: Non-urban area Rapid detection Rapid intervention (1 to 3 weeks) Secondary cases < 1.8 Prophylaxis 80-90% in region (1-3 million courses) Movement restriction and social distancing

29 Phase IV Preparedness

30

31

32 Q: Which is more important, early detection or early response, or, put differently How is an ineffective surveillance system like a clinical case of polio?

33

34 Phase VI Preparedness

35 Come one, come all to the Humanitarian Circus

36 The Singular Goal To limit excess mortality during a pandemic

37 Assumptions Country capacity will be exceeded Vaccines and anti-virals will not be available in adequate quantity Substantial mortality will be due to illnesses other than influenza Time required for action will be limited Funding will be available for response Limiting impact will be dependent on community-level actions

38 I -- Limit Direct Impact Care for those ill with influenza Vaccine? Antivirals? Limit transmission of influenza but how? Community mitigation (non-pharmaceutical interventions)

39 Martin Cetron, MD Director, Division of Global Migration and Quarantine Centers for Disease Control and Prevention 1 Delay outbreak peak Daily Cases Pandemic Outbreak: No Intervention 2 3 Decompress peak burden on hospitals/infrastructure Diminish overall cases and health impacts Pandemic Outbreak: With Intervention Days Since First Case

40 Isolation of those ill Community Mitigation Voluntary quarantine of household members Social distancing of children (close schools?) Social distancing of adults (stagger working hours, close places of employment, places of worship, places of amusement)

41 SOCIAL DISTANCING If the birds can do it.

42 II -- Reduce Indirect Impact Treat potentially fatal diseases when health services are disrupted Bacterial pneumonia Malaria Diarrhea AIDS Tuberculosis Diabetes Hypertension and other CVDs Mental disorders and other NCDs Ensure food security Accelerate resumption of livelihoods

43 Proposed Activities Identify human resources Develop detailed plans Adapt normative guidance to local needs Conduct simulations at district/municipal level Train first responders Deploy pandemic flu kits Ascertain material needs Off the shelf response capacity

44 Specifics of USAID Program IFRC United Nations agencies CORE Group Save, World Vision, CARE AI.COMM, STOP AI Interaction Schools of Public Health US Government agencies

45 Foundation for Recent Estimates

46 Illustrative Estimated Mortality

47 Illustrative Estimated Total Deaths

48 Stage I First visit Dec 07 May 08 Proposed Country Selection Stage II First visit June 08 Nov 08 Stage III First visit Dec 08 May 09 Stage IV First visit June 09 Oct 09 Egypt Mali TBD TBD TBD Ethiopia Uganda TBD TBD TBD Rwanda Angola TBD TBD TBD Nepal Bangladesh TBD TBD TBD Cambodia Malawi TBD TBD TBD Stage V First visit Nov 09 Mar 09 Laos Azerbaijan Ukraine Tanzania DRC Madagascar India Other countries being considered Benin Nigeria Kenya Senegal Haiti Bolivia Indonesia Philippines Pakistan Liberia Sudan Peru South Africa Zambia Afghanistan Ghana Nicaragua Mozambique Burundi

49 The Three P s of Pandemic Preparedness Plan Practice Pray (not necessarily in that order)

50

51

52

53

54 Recommendation (2005) An improved seismic detection system should be developed and implemented in the region as quickly as possible.

55 The only thing more difficult than planning for a pandemic would be explaining why you did not do it

56

Pandemic H1N Dr. Maria Neira Global Influenza Programme WHO, Geneva

Pandemic H1N Dr. Maria Neira Global Influenza Programme WHO, Geneva Pandemic H1N1 2010 Dr. Maria Neira Global Influenza Programme WHO, Geneva WHO Role during pandemic (H1N1) 2009 Under the International Health Regulations (2005) Detect event (notification by Member States

More information

Annex 2 A. Regional profile: West Africa

Annex 2 A. Regional profile: West Africa Annex 2 A. Regional profile: West Africa 355 million people at risk for malaria in 215 297 million at high risk A. Parasite prevalence, 215 Funding for malaria increased from US$ 233 million to US$ 262

More information

Pandemic Influenza: Hype or Reality?

Pandemic Influenza: Hype or Reality? Pandemic Influenza: Hype or Reality? Leta Finch Executive Director, Higher Education Practice 2003 Arthur J. Gallagher & Co. Objectives Review key characteristics of influenza, including differences between

More information

Avian Influenza Prevention and Preparedness: Global and Regional Strategies and Actions

Avian Influenza Prevention and Preparedness: Global and Regional Strategies and Actions Avian Influenza Prevention and Preparedness: Global and Regional Strategies and Actions 8 February, 2006 Thammasat University and Asian Disaster Preparedness Center Bangkok, Thailand What will be presented

More information

Overview of human cases of AI H5N1 since 1997

Overview of human cases of AI H5N1 since 1997 Overview of human cases of AI H5N1 since 1997 Dr Sylvie Briand WHO Global Influenza Programme 7 October 2008 1 FAO-OIE- WHO Joint Technical Consultation on AI at the Human-Animal Interface Review of the

More information

DRAFT WGE WGE WGE WGE WGE WGE WGE WGE WGE WGE WGE WGE WGE WGE GETREADYNOWGE GETREADYNOWGE GETREADYNOWGE GETREADYNOWGE.

DRAFT WGE WGE WGE WGE WGE WGE WGE WGE WGE WGE WGE WGE WGE WGE GETREADYNOWGE GETREADYNOWGE GETREADYNOWGE GETREADYNOWGE. What Can I Do As A National Leader? This publication was produced by the AI.COMM project, managed by the Academy for Educational Development (AED), and funded by the U.S. Agency for International Development

More information

Wild Poliovirus*, 03 Aug 2004 to 02 Aug 2005

Wild Poliovirus*, 03 Aug 2004 to 02 Aug 2005 Wild Poliovirus*, 03 Aug 2004 to 02 Aug 2005 Wild virus type 1 Wild virus type 3 Wild virus type 1 & 3 Endemic countries Re-established transmission countries Case or outbreak following importation *Excludes

More information

INFLUENZA WATCH Los Angeles County

INFLUENZA WATCH Los Angeles County January 3, 2007: Vol.1, Issue 2 Surveillance Week: 12/24/06 12/30/06 INFLUENZA WATCH Los Angeles County http://lapublichealth.org/acd/flu.htm SURVEILLANCE SYSTEM* Week 52 To Date Positive Influenza Tests±

More information

GLOBAL AND REGIONAL SITUATION OF AVIAN INFLUENZA

GLOBAL AND REGIONAL SITUATION OF AVIAN INFLUENZA GLOBAL AND REGIONAL SITUATION OF AVIAN INFLUENZA Dr Gounalan Pavade OIE Regional Expert Group Meeting for the Control of Avian Influenza in Asia Sapporo, Japan 3-5 October 2017 1 Avian influenza Outbreaks

More information

USAID s approach to the control of avian and pandemic influenza

USAID s approach to the control of avian and pandemic influenza USAID s approach to the control of avian and pandemic influenza Murray Trostle, Dr. PH Deputy Director Avian and Pandemic Influenza Unit USAID December 19, 2006 USAID goals Prevent an influenza pandemic

More information

New Delhi International Ministerial Conference on Avian and Pandemic Influenza Dec 4-6th, 2007

New Delhi International Ministerial Conference on Avian and Pandemic Influenza Dec 4-6th, 2007 New Delhi International Ministerial Conference on Avian and Pandemic Influenza Dec 4-6th, 2007 Session IV Influenza Pandemic Preparedness Dr Paul R Gully Health Security and Environment, Geneva Avian Influenza

More information

Avian Influenza (Bird Flu) Fact Sheet

Avian Influenza (Bird Flu) Fact Sheet What is an avian influenza A (H5N1) virus? Influenza A (H5N1) virus also called H5N1 virus is an influenza A virus subtype that occurs mainly in birds. It was first isolated from birds (terns) in South

More information

Avian influenza Avian influenza ("bird flu") and the significance of its transmission to humans

Avian influenza Avian influenza (bird flu) and the significance of its transmission to humans 15 January 2004 Avian influenza Avian influenza ("bird flu") and the significance of its transmission to humans The disease in birds: impact and control measures Avian influenza is an infectious disease

More information

Global reductions in measles mortality and the risk of measles resurgence

Global reductions in measles mortality and the risk of measles resurgence Global reductions in measles mortality 2000 2008 and the risk of measles resurgence Measles is one of the most contagious human diseases. In 1980 before the use of measles vaccine was widespread, there

More information

Conflict of Interest and Disclosures. Research funding from GSK, Biofire

Conflict of Interest and Disclosures. Research funding from GSK, Biofire Pandemic Influenza Suchitra Rao, MBBS, Assistant Professor, Pediatric Infectious Diseases, Hospital Medicine and Epidemiology Global Health and Disasters Course, 2018 Conflict of Interest and Disclosures

More information

Matt Smith. Avian Flu Model

Matt Smith. Avian Flu Model Robert Smith? Patrick O Brian Matt Smith Avian Flu Model MAT3395 April 27, 2009 Objectives -Estimate the size of an outbreak if a shift occurred in the disease -determine if quarantine would be as effective

More information

MI Flu Focus. Influenza Surveillance Updates Bureaus of Epidemiology and Laboratories

MI Flu Focus. Influenza Surveillance Updates Bureaus of Epidemiology and Laboratories MI Flu Focus Influenza Surveillance Updates Bureaus of Epidemiology and Laboratories Editor: Susan Peters, DVM PetersS1@michigan.gov January 3, 2013 Surveillance and Infectious Disease Epidemiology Vol.

More information

OIE Situation Report for Avian Influenza

OIE Situation Report for Avian Influenza OIE Situation Report for Avian Influenza Latest update: 25/01/2018 The epidemiology of avian influenza is complex. The virus constantly evolves and the behavior of each new subtype (and strains within

More information

The Demographic Impact of an Avian Flu Pandemic

The Demographic Impact of an Avian Flu Pandemic The Demographic Impact of an Avian Flu Pandemic Emile Stipp 13 May 27 Overview Based on paper authored also by Dr Glenn Staples, Cassie Hamman and Jaco van der Merwe Influenza overview Avian Influenza

More information

OIE Situation Report for Highly Pathogenic Avian Influenza

OIE Situation Report for Highly Pathogenic Avian Influenza OIE Situation Report for Highly Pathogenic Avian Influenza Latest update: 28/02/2018 The epidemiology of avian influenza is complex. The virus constantly evolves and the behavior of each new subtype (and

More information

Experiences on Workforce Development in Other Regions

Experiences on Workforce Development in Other Regions Experiences on Workforce Development in Other Regions The USA Experience John MacArthur, MD, MPH (EIS 98) Director Thailand MOPH US CDC Collaboration CDC/Southeast Asia Regional Office Epidemic Intelligence

More information

Pandemic Planning Update. Anita L. Barkin, DrPH, MSN, CRNP ACHA Annual Meeting Orlando, Florida 2008

Pandemic Planning Update. Anita L. Barkin, DrPH, MSN, CRNP ACHA Annual Meeting Orlando, Florida 2008 Pandemic Planning Update Anita L. Barkin, DrPH, MSN, CRNP ACHA Annual Meeting Orlando, Florida 2008 Current Status of H5N1 383 human cases (5/29/08) 62% fatality rate Median age 18-20 previously healthy

More information

Regional Overview of the implementation of National Control Strategies for Avian Influenza. Summary review of questionnaire OIE RRAP

Regional Overview of the implementation of National Control Strategies for Avian Influenza. Summary review of questionnaire OIE RRAP Regional Overview of the implementation of National Control Strategies for Avian Influenza Summary review of questionnaire OIE RRAP The OIE Questionnaire on Influenza A surveillance in animals in the Asia

More information

WHO Global Task Force on TB Impact Measurement An overview

WHO Global Task Force on TB Impact Measurement An overview WHO Global Task Force on TB Impact Measurement An overview Katherine Floyd (WHO/GTB/TME) 3 rd meeting of the TB estimates subgroup Glion-sur-Montreux, 31March 2 April 2015 GLOBAL TB PROGRAMME 1. Broad

More information

Current State of Global HIV Care Continua. Reuben Granich 1, Somya Gupta 1, Irene Hall 2, John Aberle-Grasse 2, Shannon Hader 2, Jonathan Mermin 2

Current State of Global HIV Care Continua. Reuben Granich 1, Somya Gupta 1, Irene Hall 2, John Aberle-Grasse 2, Shannon Hader 2, Jonathan Mermin 2 Current State of Global HIV Care Continua Reuben Granich 1, Somya Gupta 1, Irene Hall 2, John Aberle-Grasse 2, Shannon Hader 2, Jonathan Mermin 2 1) International Association of Providers of AIDS Care

More information

- Avian and Human Pandemic Influenzas Update - Number as reported to WHO

- Avian and Human Pandemic Influenzas Update - Number as reported to WHO Issue Brief The World Bank - Avian and Human Pandemic Influenzas Update - The spread of avian influenza continues. To date, the virus has resulted in 28 human deaths and affected wild birds and poultry

More information

Update from GAVI Aurelia Nguyen

Update from GAVI Aurelia Nguyen Update from GAVI Aurelia Nguyen (Copenhagen, Denmark, 27 June 2012) GAVI vaccine support Currently supported vaccines: pentavalent, pneumococcal, rotavirus, meningitis A, human papillomavirus (HPV), rubella,

More information

Research Issues in Animal Surveillance and Pandemic Planning

Research Issues in Animal Surveillance and Pandemic Planning Research Issues in Animal Surveillance and Pandemic Planning Robert G. Webster, PhD Division of Virology Department of Infectious Diseases St. Jude Children s Research Hospital SURVEILLANCE Spread of H5N1

More information

OIE Situation Report for Highly Pathogenic Avian Influenza

OIE Situation Report for Highly Pathogenic Avian Influenza OIE Situation Report for Highly Pathogenic Avian Influenza Latest update: 31/05/2018 The epidemiology of avian influenza (AI) is complex. The AI virus constantly evolves by mutation and re-assortment with

More information

Global Measles and Rubella Update. April 2018

Global Measles and Rubella Update. April 2018 Global Measles and Rubella Update April 218 Measles Number of Reported Measles by WHO Regions 218 Region Member States* Suspected cases Measles cases Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep Oct

More information

TB Disease Prevalence Survey - Progress Report

TB Disease Prevalence Survey - Progress Report TB Disease Prevalence Survey - Progress Report 30 Oct 2011, Lille Ikushi Onozaki MD, MPH Team Leader, TB Prevalence Survey WHO Global Task Force on TB Impact Measurement Stop TB Department, WHO onozakii@who.int

More information

Impact Dashboard - October 2014

Impact Dashboard - October 2014 Impact Dashboard - 2014 By 2014, PSI and its network members averted an estimated 44.2 million DALYs globally. PSI has met 60.6% of the strategic plan (SP) target to avert 198.7 million DALYs, and 56.4%

More information

New Hampshire Institute for Local Public Health Practice

New Hampshire Institute for Local Public Health Practice New Hampshire Institute for Local Public Health Practice Collaborative Initiative Between The City of Manchester Health Department & The New Hampshire Department of Health and Human Services Funding provided

More information

Global Measles and Rubella Update November 2018

Global Measles and Rubella Update November 2018 Global Measles and Rubella Update November 218 Measles Number of Reported Measles by WHO Regions 218 Region Member States* Suspected cases Measles cases Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep

More information

Impact Dashboard - August 2014

Impact Dashboard - August 2014 Impact Dashboard - By, PSI and its network members averted an estimated 29.7 million DALYs globally. PSI has met 53.3% of the strategic plan (SP) target to avert 198.7 million DALYs, and 53.0% of the SP

More information

Emerging Infectious Disease Categories (NIAID) 1 of 3

Emerging Infectious Disease Categories (NIAID) 1 of 3 Emerging Diseases Emerging Infectious Disease Categories (NIAID) 1 of 3 Category A Priority Pathogens Category A pathogens are those organisms/biological agents that pose the highest risk to national security

More information

INFLUENZA-2 Avian Influenza

INFLUENZA-2 Avian Influenza INFLUENZA-2 Avian Influenza VL 7 Dec. 9 th 2013 Mohammed El-Khateeb Overview 1. Background Information 2. Origin/History 3. Brief overview of genome structure 4. Geographical Distribution 5. Pandemic Nature

More information

Global Catastrophic Biological Risks

Global Catastrophic Biological Risks Global Catastrophic Biological Risks Working Definition of Global Catastrophic Biological Risks (GCBRs) Events in which biological agents whether naturally emerging or reemerging, deliberately created

More information

Comparative Analyses of Adolescent Nutrition Indicators

Comparative Analyses of Adolescent Nutrition Indicators Comparative Analyses of Adolescent Nutrition Indicators Rukundo K. Benedict, PhD The DHS Program Stakeholders Consultation on Adolescent Girls Nutrition: Evidence, Guidance, and Gaps October 30 31, 2017

More information

Pneumococcal Conjugate Vaccine: Current Supply & Demand Outlook. UNICEF Supply Division

Pneumococcal Conjugate Vaccine: Current Supply & Demand Outlook. UNICEF Supply Division Pneumococcal Conjugate Vaccine: Current Supply & Demand Outlook UNICEF Supply Division Update: October 2013 0 Pneumococcal Conjugate Vaccine (PCV) Supply & Demand Outlook October 2013 Update Key updates

More information

Pandemic Flu: Preplanning for an Outbreak

Pandemic Flu: Preplanning for an Outbreak Pandemic Flu: Preplanning for an Outbreak Presented to AACRAO Leta Finch Executive Director, Higher Education Practice Group Arthur J. Gallagher Risk Management Services, Inc. 2006 Arthur J. Gallagher

More information

Influenza: The Threat of a Pandemic

Influenza: The Threat of a Pandemic April, 2009 Definitions Epidemic: An increase in disease above what you what would normally expect. Pandemic: A worldwide epidemic 2 What is Influenza? Also called Flu, it is a contagious respiratory illness

More information

Foot-and-Mouth Disease Situation Food and Agriculture Organization of the United Nations Monthly Report

Foot-and-Mouth Disease Situation Food and Agriculture Organization of the United Nations Monthly Report Foot-and-Mouth Disease Situation Food and Agriculture Organization of the United Nations Monthly Report October 2013 I N F O R M A T I O N S O U R C E S U S E D: Databases: OIE WAHID World Animal Health

More information

Global Challenges of Pandemic and Avian Influenza. 19 December 2006 Keiji Fukuda Global influenza Programme

Global Challenges of Pandemic and Avian Influenza. 19 December 2006 Keiji Fukuda Global influenza Programme Global Challenges of Pandemic and Avian Influenza 19 December 2006 Keiji Fukuda Global influenza Programme Summary of Current H5N1 Situation 1997 First known outbreak infecting humans 18 people hospitalized

More information

What is this document and who is it for?

What is this document and who is it for? Measles and Rubella Initiative s Standard Operating Procedures for Accessing Support for Measles and Rubella Supplementary Immunization Activities During 2016 In the context of measles and rubella elimination

More information

Promoting Public Health Security Addressing Avian Influenza A Viruses and Other Emerging Diseases

Promoting Public Health Security Addressing Avian Influenza A Viruses and Other Emerging Diseases Promoting Public Health Security Addressing Avian Influenza A Viruses and Other Emerging Diseases Masaya Kato, WHO Viet Nam OIE Regional Workshop on Enhancing Influenza A viruses National Surveillance

More information

Before and during influenza pandemics

Before and during influenza pandemics before and during influenza pandemics Klaus Stöhr Department for Communicable Diseases Surveillance and Response Before and during influenza pandemics Before pandemics: interpandemic period New human influenza

More information

OIE Situation Report for Avian Influenza

OIE Situation Report for Avian Influenza OIE Situation Report for Avian Influenza Latest update: 24/04/2017 This report presents an overview of current disease events reported to the OIE by its Members. The objective is to describe what is happening

More information

H5N1 avian influenza: timeline

H5N1 avian influenza: timeline H5N1 avian influenza: timeline 28 October 2005 Previous events in Asia 1996 Highly pathogenic H5N1 virus is isolated from a farmed goose in Guangdong Province, China. 1997 Outbreaks of highly pathogenic

More information

impact dashboard - august 2018

impact dashboard - august 2018 impact dashboard - august 2018 PSI 2015 As of August, PSI averted an estimated 15.2 M DALYs, provided 10.9 M CYPs, and reached 16.7 M users globally. Globally PSI has reached at least 16.7 million users

More information

Challenges and Opportunities to Optimizing the HIV Care Continuum Can We Test and Treat Enough People to Make a Seismic Difference by 2030?

Challenges and Opportunities to Optimizing the HIV Care Continuum Can We Test and Treat Enough People to Make a Seismic Difference by 2030? Challenges and Opportunities to Optimizing the HIV Care Continuum Can We Test and Treat Enough People to Make a Seismic Difference by 2030? Reuben Granich, MD, MPH Strategic and Scientific Advisor International

More information

Highly Pathogenic Avian Influenza Worldwide situation Larnaca, Cyprus, July 2009

Highly Pathogenic Avian Influenza Worldwide situation Larnaca, Cyprus, July 2009 Highly Pathogenic Avian Influenza Worldwide situation Larnaca, Cyprus, 20-22 July 2009 Dr Ghazi Yehia OIE Regional Representative for the Middle East HPAI Subtype H5N1: sequence of events 2003-2004: confined

More information

SGCEP SCIE 1121 Environmental Science Spring 2012 Section Steve Thompson:

SGCEP SCIE 1121 Environmental Science Spring 2012 Section Steve Thompson: SGCEP SCIE 1121 Environmental Science Spring 2012 Section 20531 Steve Thompson: steventhompson@sgc.edu http://www.bioinfo4u.net/ 1 First, a brief diversion... Into... how to do better on the next exam,

More information

To Tie the Knot or Not: A Case for Permanent Family Planning Methods

To Tie the Knot or Not: A Case for Permanent Family Planning Methods To Tie the Knot or Not: A Case for Permanent Family Planning Methods Presented at the GH Mini-University Washington, D.C., October 8, 2010 By Lynn Bakamjian, MPH Project Director, RESPOND/EngenderHealth

More information

University of Colorado Denver. Pandemic Preparedness and Response Plan. April 30, 2009

University of Colorado Denver. Pandemic Preparedness and Response Plan. April 30, 2009 University of Colorado Denver Pandemic Preparedness and Response Plan April 30, 2009 UCD Pandemic Preparedness and Response Plan Executive Summary The World Health Organization (WHO) and the Centers for

More information

Pandemic Influenza Preparedness

Pandemic Influenza Preparedness Pandemic Influenza Preparedness Of the many health threats that we are preparing for, this is the one that we know will happen. Bruce G. Gellin, MD, MPH Director, National Vaccine Program Office Department

More information

#TEAM45. Fundraising Guide

#TEAM45. Fundraising Guide #TEAM45 Fundraising Guide Action Against Hunger USA One Whitehall Street, 2nd Floor New York, NY 10004 212.967.7800 info@actionagainsthunger.org www.actionagainsthunger.org WELCOME TO #TEAM45! Thank you

More information

Eligibility List 2018

Eligibility List 2018 The Global Fund s 2017-2022 strategy and allocation-based approach enables strategic investment to accelerate the end of HIV/AIDS, tuberculosis and malaria and build resilient and sustainable systems for

More information

Planning for Pandemic Flu

Planning for Pandemic Flu Planning for Pandemic Flu To: Town of Middleton Administration From: Middleton Health Department 2008 1 Influenza In people, a disease of the respiratory tract caused by a virus and usually associated

More information

Prioritizing Emergency Polio Eradication Activities

Prioritizing Emergency Polio Eradication Activities Prioritizing Emergency Polio Eradication Activities Managing the Financing Gap the other half of the Emergency Hamid Jafari GPEI Financing 2012-13: Budget = $2.23 b - Confirmed contributions = $1.14 b

More information

Guidance for Travelers on Temporary Work Assignment Abroad

Guidance for Travelers on Temporary Work Assignment Abroad infected person to immediately seek medical care but, prior to arrival, notify their healthcare provider that they may have been exposed to AI. For more information about avian influenza, see www.cdc.gov/flu/avian/facts.htm,

More information

SEA/CD/154 Distribution : General. Avian Influenza in South-East Asia Region: Priority Areas for Research

SEA/CD/154 Distribution : General. Avian Influenza in South-East Asia Region: Priority Areas for Research SEA/CD/154 Distribution : General Avian Influenza in South-East Asia Region: Priority Areas for Research World Health Organization Publications of the World Health Organization enjoy copyright protection

More information

U.S. Funding for International Family Planning & Reproductive Health

U.S. Funding for International Family Planning & Reproductive Health April 2016 Issue Brief U.S. Funding for International Family Planning & Reproductive Health SUMMARY The U.S. government has supported international family planning and reproductive health (FP/RH) efforts

More information

Recipients of development assistance for health

Recipients of development assistance for health Chapter 2 Recipients of development assistance for health Both low- and middle-income countries are eligible for development assistance for health (DAH). In addition to income, burden of disease, which

More information

OIE Situation Report for Avian Influenza

OIE Situation Report for Avian Influenza OIE Situation Report for Avian Influenza Latest update: 18/09/2017 This report presents an overview of current disease events reported to the OIE by its Members. The objective is to describe what is happening

More information

Influenza: Seasonal, Avian, and Otherwise

Influenza: Seasonal, Avian, and Otherwise Influenza: Seasonal, Avian, and Otherwise Lisa Winston, MD University of California, San Francisco San Francisco General Hospital Influenza biology Antiviral medications Seasonal influenza Vaccination

More information

Viet Nam Avian Influenza Control and Preparedness

Viet Nam Avian Influenza Control and Preparedness 2008/SOM3/HWG/WKSP/004 Viet Nam Avian Influenza Control and Preparedness Submitted by: Viet Nam Health Working Group Policy Dialogue and Risk Communications Workshop Lima, Peru 13-15 August 2008 Vietnam

More information

Global Measles and Rubella Update October 2018

Global Measles and Rubella Update October 2018 Global Measles and Rubella Update October 218 Measles Number of Reported Measles Cases by WHO Regions 218 Region Member States* Suspected cases Measles cases Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug

More information

Poliovirus : éradication pour les prochaines JNI?

Poliovirus : éradication pour les prochaines JNI? Poliovirus : éradication pour les prochaines JNI? Bruno LINA CNR des entérovirus Laboratoire de virologie EST, GHE, HCL FRE 3011 CNRS UCBL, Lyon Polio Eradication Initiative 1 Polio Eradication Progress

More information

Influenza and the Poultry Link

Influenza and the Poultry Link Influenza and the Poultry Link Hemagglutinin Neuraminidase Type A Influenza Surface Antigens Subtype Surface Antigens Hemagglutinin 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 human equine swine Neuraminidase

More information

Update on Progress and Challenges in Achieving Measles and Rubella Targets

Update on Progress and Challenges in Achieving Measles and Rubella Targets Update on Progress and Challenges in Achieving Measles and Rubella Targets SAGE Meeting 6 November 2013 P. Strebel, WHO/IVB/EPI Overview Global progress Regional updates Summary 2 Measles and Rubella Targets

More information

PANDEMIC INFLUENZA PREPAREDNESS: STATE CHALLENGES

PANDEMIC INFLUENZA PREPAREDNESS: STATE CHALLENGES PANDEMIC INFLUENZA PREPAREDNESS: STATE CHALLENGES A Presentation to the Council of State Governments Health Policy Forum by Jeffrey Levi, Ph.D., Executive Director Trust for America s Health June 23, 2006

More information

impact dashboard - september 2018

impact dashboard - september 2018 impact dashboard - september 2018 PSI 2015 As of, PSI averted an estimated 17.1 M DALYs, provided 12.5 M CYPs, and reached 18.4 M users globally. Globally PSI has reached at least 18.4 million users across

More information

OFFLU AVIAN INFLUENZA REPORT

OFFLU AVIAN INFLUENZA REPORT OFFLU AVIAN INFLUENZA REPORT Avian Influenza Events in Animals for the period February to September 2017 Scope In this document we present a summary of H5, H7, and H9 avian influenza events that occurred

More information

OIE Situation Report for Highly Pathogenic Avian Influenza

OIE Situation Report for Highly Pathogenic Avian Influenza OIE Situation Report for Highly Pathogenic Avian Influenza Latest update: 30/06/2018 The epidemiology of avian influenza (AI) is complex. The AI virus constantly evolves by mutation and re-assortment with

More information

Disaster Response Team

Disaster Response Team Disaster Response Team Pandemic Flu January 22, 2009 Topics History Pandemic Characteristics Seasonal Flu vs Pandemic Flu Pandemic Estimates Sea Ranch Plans Sonoma County Public Health Pandemic Flu Planning

More information

Health Task Force Workplan

Health Task Force Workplan 2006/SOM 3/HTF/021 Agenda Item: VI Health Task Force Workplan 2006-2007 Purpose: Information Submitted by: Chair Health Task Force Meeting Da Nang, Viet Nam 14 15 September 2006 APEC HEALTH TASK FORCE

More information

impact dashboard - june 2018

impact dashboard - june 2018 impact dashboard - june 2018 As of June, PSI averted an estimated 11.3 M DALYs, provided 8.1 M CYPs, and reached 12.5 M users globally. Ethiopia, Zambia, and Cameroon have made considerable progress on

More information

AVIAN INFLUENZA AND PROGRAMME GUIDELINES FOR ITS PREVENTION AND CONTROL IN PAKISTAN

AVIAN INFLUENZA AND PROGRAMME GUIDELINES FOR ITS PREVENTION AND CONTROL IN PAKISTAN AVIAN INFLUENZA AND PROGRAMME GUIDELINES FOR ITS PREVENTION AND CONTROL IN PAKISTAN Lt. Gen (R) K.A.Karamat 1 Dr. F.H Khattak 2 Beenish Mahmood 3 INTRODUCTION AVIAN INFLUENZA (BIRD FLU) Bird flu, or avian

More information

Evaluating the Economic Consequences of Avian Influenza (1) Andrew Burns, Dominique van der Mensbrugghe, Hans Timmer (2)

Evaluating the Economic Consequences of Avian Influenza (1) Andrew Burns, Dominique van der Mensbrugghe, Hans Timmer (2) Public Disclosure Authorized Public Disclosure Authorized Public Disclosure Authorized Public Disclosure Authorized 47417 Evaluating the Economic Consequences of Avian Influenza (1) Andrew Burns, Dominique

More information

Mathematical modelling approach to estimating TB burden in children Pete Dodd (University of Sheffield) & James Seddon (Imperial College London)

Mathematical modelling approach to estimating TB burden in children Pete Dodd (University of Sheffield) & James Seddon (Imperial College London) Mathematical modelling approach to estimating TB burden in children Pete Dodd (University of Sheffield) & (Imperial College London) Wednesday, 1 April 215 Health Economics & Decision Science School of

More information

FAOAIDEnews Animal Influenza Disease Emergency

FAOAIDEnews Animal Influenza Disease Emergency FAOAIDEnews Animal Influenza Disease Emergency Situation Update 82 17 November 2011 HPAI outbreaks reported in this publication refer to officially confirmed cases only. The information is compiled from

More information

Countries initially targeted: Bangladesh, Mongolia, Myanmar, Nepal, Lao People s Demoncratic Republic and Pakistan.

Countries initially targeted: Bangladesh, Mongolia, Myanmar, Nepal, Lao People s Demoncratic Republic and Pakistan. PUI PROJECT PROPOSAL ON BUILDING AND IMPROVEMENT OF ANIMAL DISEASE DIAGNOSTIC CAPACITIES OF VETERINARY LABORATORIES IN ASIA BY TRANSFER OF NUCLEAR AND NUCLEAR RELATED TECHNIQUES: A REGIONAL APPROACH FOR

More information

Pandemic Influenza: A Zoonotic Infection. Kathleen M. Neuzil, MD, MPH PATH University of Washington School of Medicine April 28, 2008

Pandemic Influenza: A Zoonotic Infection. Kathleen M. Neuzil, MD, MPH PATH University of Washington School of Medicine April 28, 2008 Pandemic Influenza: A Zoonotic Infection Kathleen M. Neuzil, MD, MPH PATH University of Washington School of Medicine April 28, 2008 Questions What is the epidemiology of human influenza? What is the role

More information

WHO Response to Influenza A (H1N1) CAPSCA December, 2011 Dr. Nasr Eltantawy Medical epidemiologist WHO/Egypt

WHO Response to Influenza A (H1N1) CAPSCA December, 2011 Dr. Nasr Eltantawy Medical epidemiologist WHO/Egypt WHO Response to Influenza A (H1N1) 2009 CAPSCA 11-14 December, 2011 Dr. Nasr Eltantawy Medical epidemiologist WHO/Egypt Outline Background. Preparedness planning. Evolution of the pandemic. WHO and other

More information

For the control of avian influenza

For the control of avian influenza OIE Regional Expert Group Meeting for the Control of Avian influenza in Asia Sapporo, 3-5 October 2017 For the control of avian influenza Hiroshi Kida Hokkaido University Research Center for Zoonosis Control

More information

Ralph KY Lee Honorary Secretary HKIOEH

Ralph KY Lee Honorary Secretary HKIOEH HKIOEH Round Table: Updates on Human Swine Influenza Facts and Strategies on Disease Control & Prevention in Occupational Hygiene Perspectives 9 July 2009 Ralph KY Lee Honorary Secretary HKIOEH 1 Influenza

More information

Avian influenza - current situation and future trends

Avian influenza - current situation and future trends Avian influenza - current situation and future trends Calogero Terregino OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle

More information

Current Status of Highly Pathogenic Avian Influenza in Animal. Wantanee Kalpravidh Food and Agriculture and Organization

Current Status of Highly Pathogenic Avian Influenza in Animal. Wantanee Kalpravidh Food and Agriculture and Organization Current Status of Highly Pathogenic Avian Influenza in Animal Wantanee Kalpravidh Food and Agriculture and Organization Outlines Updated situation of HPAI in Asia FAO s views on current problems Perspectives

More information

O c t o b e r 1 0,

O c t o b e r 1 0, STUDENT VOICES FROM THE FIELD: WORLD HEALTH ORGANIZATION GENEVA, SWITZERLAND O c t o b e r 1 0, 2 0 1 6 M o l l y P e z z u l o University at Albany School of Public Health MPH Epidemiology Candidate 17

More information

Antigenic and genetic characteristics of H5N1 viruses and candidate H5N1 vaccine viruses developed for potential use in human vaccines

Antigenic and genetic characteristics of H5N1 viruses and candidate H5N1 vaccine viruses developed for potential use in human vaccines Antigenic and genetic characteristics of H5N1 viruses and candidate H5N1 vaccine viruses developed for potential use in human vaccines September 2008 It is not known if the next influenza pandemic will

More information

Influenza. Paul K. S. Chan Department of Microbiology The Chinese University of Hong Kong

Influenza. Paul K. S. Chan Department of Microbiology The Chinese University of Hong Kong Influenza Paul K. S. Chan Department of Microbiology The Chinese University of Hong Kong Influenza Virus Nomenclature Influenza virus A, B & C Influenza A : Haemagglutinin (H), neuraminidase (N) A H3N2,

More information

Avian Influenza: Armageddon or Hype? Bryan E. Bledsoe, DO, FACEP The George Washington University Medical Center

Avian Influenza: Armageddon or Hype? Bryan E. Bledsoe, DO, FACEP The George Washington University Medical Center Avian Influenza: Armageddon or Hype? Bryan E. Bledsoe, DO, FACEP The George Washington University Medical Center Definitions: Epidemic The occurrence of cases of an illness in a community or region which

More information

Global TB control: Current status with particular attention to TB among women and children

Global TB control: Current status with particular attention to TB among women and children Global TB control: Current status with particular attention to TB among women and children Katherine Floyd Stop TB Department World Health Organization 42 nd Union World Conference on Lung Health Stop

More information

impact dashboard - may 2018

impact dashboard - may 2018 impact dashboard - may 2018 As of May, PSI averted an estimated 8.0 M DALYs, provided 6.2 M CYPs, and reached 8.1 M users globally. In May alone, PSI added 2.6 M users toward the goal of 90 M reached by

More information

EU Market Situation for Poultry. Committee for the Common Organisation of the Agricultural Markets 20 April 2017

EU Market Situation for Poultry. Committee for the Common Organisation of the Agricultural Markets 20 April 2017 EU Market Situation for Poultry Committee for the Common Organisation of the Agricultural Markets 2 April 217 -9.% -11.% -5.% -.1% -.7% -2.2% 3.% 1.7% 1.2%.8%.6%.%.%.% 7.9% 7.% 6.4% 6.2% 6.% 5.5% 5.3%

More information

TB Disease Prevalence Survey - Overview and Introduction of the TF

TB Disease Prevalence Survey - Overview and Introduction of the TF TB Disease Prevalence Survey - Overview and Introduction of the TF Ikushi Onozaki MD, MPH Team Leader, TB Prevalence Survey WHO Global Task Force on TB Impact Measurement Stop TB Department, WHO onozakii@who.int

More information

Influenza Update N 157

Influenza Update N 157 Influenza Update N 157 13 April 2012 Summary In most areas of the northern hemisphere temperate regions, influenza activity appears to have peaked and is declining. In North America, influenza indicators

More information

Landscape Analysis on Countries' Readiness to Accelerate Action to Reduce Maternal and Child Undernutrition

Landscape Analysis on Countries' Readiness to Accelerate Action to Reduce Maternal and Child Undernutrition 35 th Session of the UN Standing Committee on Nutrition (SCN) Hanoi, 3 6 March 2008 Landscape Analysis on Countries' Readiness to Accelerate Action to Reduce Maternal and Child Undernutrition Jorgen Schlundt

More information

Rotavirus Vaccine: Supply & Demand Update. UNICEF Supply Division

Rotavirus Vaccine: Supply & Demand Update. UNICEF Supply Division Rotavirus Vaccine: & Demand Update UNICEF Division July 0 Rotavirus Vaccine (RV): & Demand Update July This update provides new information on countries and their scheduled RV introductions, forecasted

More information