2018 NW Auditory and Vestibular Research Meeting October 11-12, 2018 Schedule

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1 2018 NW Auditory and Vestibular Research Meeting Schedule Thursday, October 11, PM Registration/check in and boxed lunch in CD150 auditorium lobby 12:45 PM Opening remarks 1-2:30 PM Invited talks 2:30 PM Coffee Break 3-4:30 PM Short talks 4:45 PM Poster Session at Vista Café 6:15 PM Dinner at Vista Café Friday, October 12, :00 AM Breakfast in CD150 auditorium lobby 8:30 AM Invited talk 9:15-10:30 AM Short talks 10:30 AM Coffee Break 11 AM -12:30 PM Invited talks 12:30 PM Closing remarks

2 Thursday, October 11 in CHDD Auditorium, CD150 12:00 PM Registration check-in and boxed lunch in CD150 Auditorium Lobby 12:45 PM Welcome and Introductory remarks 1:00 PM John V. Brigande, Ph.D. (Associate Professor, OHRC, OHSU) "Gene therapy to treat congenital deafness and balance dysfunction" 1:45 PM Jennifer S. Stone, Ph.D. (Research Professor, Oto-HNS, UW) 2:30 PM Coffee break "Tilting the balance: Regulation of vestibular hair cell homeostasis and regeneration" 3:00 PM Short talks (12 min. 3 min. for questions): Avinash D Singh Bala, Ph.D. (Research Associate, Institute of Neuroscience, University of Oregon) Infant hearing assessed using the Pupil Dilation Response" Esra D. Camci, Ph.D. (Senior Fellow Trainee, Rubel lab, Oto-HNS, UW) "Differentiating Mechanisms of Aminoglycoside Toxicity In Mammalian Cochlear Hair Cells" George W. S. Burwood Ph.D. (Postdoctoral Fellow, Nuttall lab, OHRC, OHSU) "Using the salsa mouse to explore the relationship between loud sound exposure, blood flow, and hearing loss" Jesse M Resnick, Ph.D. (Graduate Trainee, Rubinstein lab, Oto-HNS, UW) "Neural Time Constants Drive Electrically Evoked Compound Action Potential Inter-phase Gap Effect" Alexandria M. Hudson, B.S. (Graduate Student, Coffin lab, Coffin lab, Washington State University Vancouver) "Berbamine analogs exhibit multimodal protection of hair cells from aminoglycosides in the zebrafish lateral line" Eric D. Thomas, B.S. (Graduate Student, Raible lab, Biological Structure, UW) "Distinct Progenitor Populations Mediate Regeneration in the Zebrafish Lateral Line" 4:45 PM Poster session & reception at the Vista Café in the Foege Building (Genome Sciences) 6:15 PM Dinner at the Vista Café in the Foege Building (Genome Sciences)

3 Friday, October 12 in CHDD Auditorium, CD150 8:00 AM Breakfast (Coffee, pastries and fruit) in CD150 Auditorium Lobby 8:30 AM Robert Peterka, Ph.D. (Associate Professor, Department of Neurology, OHSU/NCRAR, VA Portland Health Care System) 'How the Brain Combines Vestibular Semicircular Canal and Otolith Information to Determine Head Orientation' 9:15 AM Short talks (15 min); selected from student and post doctoral abstracts Brent A. Wilkerson, Ph.D. (Senior Fellow Trainee, Bermingham-McDonogh lab, Biological Structure, UW) "Open chromatin dynamics in prosensory cells of the embryonic mouse cochlea" Kristy J. Lawton, Ph.D. (Senior Fellow Trainee, Coffin lab, Washington State University Vancouver) "Hair cell death and synaptic changes in the zebrafish lateral line following noise-induced damage" Corey Shayman, B.S. (Hullar Vestibular Lab, Oto-HNS, OHSU) "Vestibular-Visual Temporal Integration and Vestibular Peripheral Sensitivity" Santiago Jaramillo, Ph.D. (Assistant Professor, Institute of Neuroscience and Department of Biology, University of Oregon) "Contribution of distinct auditory cortical inhibitory neuron types to spectral surround suppression" Itallia V. Pacentine, Ph.D. (OHSU) "Putative pore-forming subunits of the mechano-electrical transduction channel, Tmc1/2b, require Tmie to localize to the site of mechanotransduction in zebrafish hair cells" 10:30 AM Break in the CD150 Auditorium Lobby 11:00 AM David W. Raible, Ph.D. (Professor, Biological Structure, UW) "Understanding why hair cells die" 11:45 AM Allison Coffin, Ph.D. (Assistant Professor, Integrative Physiology and Neuroscience, Washington State University Vancouver) From fish to mammals: Stories of hair cell death and protection 12:30 PM Concluding remarks / announcements

4 Poster Session Thursday, October 11 th, 4:45 PM in Vista Café 01 Curtis Hartling Binaural pitch fusion in children with normal-hearing, hearing aids, and cochlear implants 02 Zachary Urdang Free Hearing Screening and Free Hearing Resources for General and Underserved Populations - OHSU's Experience 03 Richard Wright Individual and Gender Effects in Speech Intelligibility 04 Patricia Wu Differential aminoglycoside toxicity reveals distinct mechanisms of hair cell death in Zebrafish lateral line 05 Anisha Noble Spectral ripple discrimination in normal hearing infants using static and dynamic spectral resolution testing 06 Matthew Hill Misregulation of Gene Expression in the CNS and Inner Ear of the raumschiff Zebrafish Mutant 07 Anna Shipman Transmembrane channel-like protein Tmc2b can rescue vestibular defects in Tmc1/2a/2b triple mutant zebrafish 08 Andrea McQuate Mitochondrial Networks Play a Role in Hair Cell Function in the Zebrafish Lateral Line 09 Tenzin Ngodup Discovery of a Novel Inhibitory Cell Type in the Cochlear Nucleus 10 Eliot Smith Mutation of the Transcription Factor MINT/Split Ends (Spen) Causes Hearing and Balance Deficits in Danio rerio 11 Charles Williams Norepinephrine excites neurons in the shell of the mouse inferior colliculus 12 Clive Morgan Characterization of Usher Syndrome Protein Complexes 13 Zachary Schwartz Stability of frequency tuning and acoustic threshold of cortical neurons across arousal states 14 Sophie Seo Canonical Wnt signaling regulates auditory hair cell regeneration in birds

5 POSTERS AND DINNER Thursday, 4:45 PM VISTA CAFÉ William H. Foege Hall, Genome Sciences Street Address: th Ave NE, Seattle, WA Parking: Check in at Gate House #6 for directions to campus parking for the Center for Human Development and Disability (CHDD). NWAVRM TALKS (Thursday and Friday) CD150, Haring Center/EEU (CHDD) Street Address: 1701 NE Columbia Rd (Ferry Place NE) Seattle, WA

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