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1 Perimodiolar, Slim Straight and Slim Modiolar Cochlear Implant Electrode Arrays: Comparison of Performance Otcomes J. Eric Lpo MD, MS Allison Biever, AD David C. Kelsall, MD CI2017 San Francisco, CA - Jl Rocky Montain Cochlear Implant Center Colorado Nerological Institte Englewood, Colorado, USA CNI Colorado Nerological Institte
2 Presenter Disclosre Information No relationships to disclose
3 Introdction Rond window insertion with a slim straight electrode may be less tramatic and more likely to preserve hearing Perimodiolar (crved) electrode arrays tend to have lower neral response telemetry (NRT) thresholds, T and C levels and consme less power Perimodiolar electrodes may provide improved hearing performance from a more focsed, precise stimlation Do the programming parameters and otcome data for sbjects differ by type of CI electrode array?
4 Methods IRB-exempt, retrospective comparative stdy Three grops of sbjects Perimodiolar array (CI24RE or CI512) Thin straight array (CI422/522) Slim modiolar array(ci532) Stdy period Jly 2012 to Jn 2017 of srgeries performed at a single CI center FDA criteria met for implantation Assessment Programming parameters - T and C Levels as well as NRT thresholds AzBios sentences and CNC word performance at 3, 6, and 12 months postactivation Hearing preservation Statistical comparison by 1-way ANOVA
5 Demographics Grops Sbjects Age (years) At srgery Perimodiolar (CI24RE /CI512) Thin straight (CI422 /CI522) Slim modiolar (CI532) N=64 Range: yrs Mean: 62 yrs N=62 Range: yrs Mean: 65 yrs N=35 Range: yrs Mean: 61 yrs TOTAL N=160 Range: yrs Mean: 63 yrs
6 T and C levels Initial Activation Average T Levels by Implant Type Average C Levels by Implant Type T Level (nc/ph) CI24Re (n=64) CI532 (n=34) CI422 (n=62) C Level (nc/ph) Electrode No Electrode No.
7 T and C levels - 6 months Average T Levels by Implant Type Average C Levels by Implant Type T Level (nc/ph) CI24RE (n=64) CI532 (n=25) CI4222 (n=62) C Level (nc/ph) Electrode No Electrode No.
8 NRT thresholds by implant type NRT Threshold (CL Units) Average NRT Thresholds at 3 mo. by Implant Type CI422 (n=57) CI24RE/CI512 (n=57) CI532 (n=28) Electrode No.
9 Otcome Data Sentences in Qiet % Correct SCORE % Pre 3m 6m 12m Pre 3m 6m 12m Pre 3m 6m 12m No statistically significant performance difference seen at 3m, 6m, 12m 3m: F(2,152) = 2.691, p = m: F(2,112) = 2.89, p = m: F(2,82) = 0.669, p = 0.52
10 Otcome Data Words in Qiet % Correct Pre 3m 6m 12m Pre 3m 6m 12m Pre 3m 6m 12m No statistically significant performance difference seen at 3m, 6m, 12m 3m: F(2,114) = , p = m: F(2,105) = 1.203, p = m: F(2,76) = , p = 0.52
11 Otcome Data Sentences in Noise % Correct Perimodiolar Thin Straight Slim modiolar No statistically significant performance difference seen F(2,66) = 1.995, p = 0.14
12 Hearing Preservation - Perimodiolar LF PTA (db HL) Pre-op IniGal 2 wk Latest 11m < > Total N LF PTA - Low Freqency Pre Tone Average (250 and 500 Hz) Initial Activation at 2 weeks Latest follow p average 0.9y range y LF PTA <85 db: 31/64 pt - 49% LF Hearing Preservation: 7/31 pt - 22%
13 Hearing Preservation -Thin straight LF PTA (db HL) Pre-op IniGal 2 wk Latest 12m < > Total N LF PTA - Low Freqency Pre Tone Average (250 and 500 Hz) Initial Activation at 2 weeks Latest follow p average 1.0y range y LF PTA <85 db: 54/62 pt - 87% LF Hearing Preservation: 16/54 pt - 30%
14 Hearing Preservation - Slim modiolar LF PTA (db HL) Pre-op IniGal -2 wk Latest - 4m < > Total N LF PTA - Low Freqency Pre Tone Average (250 and 500 Hz) Initial Activation at 2 weeks Latest follow p average 0.3y range 0.5-1y LF PTA <85 db: 24/35 pt - 69% LF Hearing Preservation: 8/24 pt - 33%
15 Slim Modiolar Adiological Experience With the slim modiolar array, impedances are more niform, and tend to be low. Unsal to have electrodes ot of voltage compliance. Becase electrodes are in voltage compliance, and T-levels are relatively niform, faster programming time noted. Fewer T-levels need to be measred and interpolation is more accrate. Battery power consmption appears lower, leading to longer battery life, which is extremely important for Kanso recipients. Despite hearing preservation with the thin straight and slim modiolar, patients are preferring to tilze the Kanso processor and forgo an acostic component.
16 Conclsions T and C vales similar between perimodiolar and slim modiolar electrode No statistically significant difference in sentence and word performance amongst electrodes To date with early data, LFHP possible with slim modiolar at rate similar to thin straight Early Adiological experience Stdy Limitations Limitations inherent in retrospective review Continal accral of data for the slim modiolar array Confonders not controlled for ie. Srgical approach
17 Acknowledgements Jdith Stckey MS CNI Rocky Montain Ear Center Adiologists Megan Read AD Rebecca Kyllonen AD Shawna Steib AD Kevin Peterson 4 th year RMEC/Cochlear Corp AD extern Kimberly Nix Cochlear Corp T/C, NRT data collection Allysa Biever Data collection CNI Colorado Nerological Institte
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