檵檵檵檵檵檵檵檵檵檵檵檵檵檵檵 殝 殝. chromium yttrium - scandium - gallium - garnet laser Nd YAG neodymium yttrium - aluminium

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1 1 檵 檵檵檵檵檵檵檵檵檵檵檵檵檵檵檵 SCI % R A DOI: /j.cnki.kqyx Application of laser in periodontal therapy PAN Yaping. Department of Periodontology School of Stomatology China Medical University Liaoning Institute of Dental Research Shenyang China Abstract To summarize the application of laser in the treatment of periodontal disease. Researches have proved that laser can clean more than 97% periodontal pathogens and laser also can remove infected cementum effectively with little damage on periodontal tissue and tooth root. Laser also can alleviate pain in treatment. So laser may have potential application in periodontal therapy in future. Key words laser periodontal pathogens periodontal treatment periodontal surgery Stomatology CO nm CO 2 carbon dioxide la- ~ W 50 ser Er Cr YSGG erbium 40 chromium yttrium - scandium - gallium - garnet laser Nd YAG neodymium yttrium - aluminium - garnet laser Er YAG erbium - doped yttrium aluminium and garnet laser gallium - aluminum - arsenide diode laser yppan@ mail. cmu. edu. cn 1. 1 CO 2 CO 2 CO 2

2 Er Cr YSGG Er Cr YSGG prevotella intermedia Pi tannerella forsythia Tf fusobacterium nuclea- Er Cr YSGG nm tum Fn parvimonas micra Pm nm 6 15 s Yaneva 3 90% Er YAG Nd YAG Nd YAG nm Er YAG 97% ~ 100% 4 Giannelli 5 DNA Nd YAG 3 W 2. 0 ± 1. 0 mm Er YAG 1. 4 Er YAG CO 2 Er YAG nm Nd YAG Nd YAG Nd YAG ~ nm Nd YAG 2 scaling and root planning SRP β IL - 1β - α TNF - α P < SRP P < matrix metalloproteinase mm Kranendonk 2 Nd YAG 6 W 50 CO 2 Hz 5 s aggregatibacter actinomycetemcomitans Aa porphyromonas gingivalis Pg CO 2 MMP - 8 SRP P

3 3 < GSH - Px 15 alkaline phosphatase ALP 9 Nd YAG Er YAG EDTA GSH - Px ALP CO 2 Er YAG tartrate - resistant acid phosphatase TRAP Er YAG P > CO 2 Er YAG 17 Er 10 Pavone 11 YAG SRP SRP SRP SRP 18 TRAP P < P > SRP SRP P < SRP SRP Nd YAG CO 2 SRP Er YAG Er Cr YSGG Dilsiz mm P < Nd YAG ALP Runx2 Ⅰ 14 Er Cr YSGG P < SRP P > Nd YAG SRP SRP 25-27

4 Sawabe 29 Er YAG SRP Sanz - Moliner 30 CO 2 P < Er Cr YS- GG CO chronic periodontitis preliminary results J 4 Tosun E Tasar F Strauss R et al. Comparative evaluation of anti- microbial effects of Er YAG diode and CO 2 discs an experimental study J Giannelli M Bani D Viti C Nd YAG gingiva of periodontopathic patients J Nd YAG 6 Gómez C Domínguez A García-Kass AI YAG laser application in chronic periodontitis clinical 150 s / 35 ical and microbiological aspects J stün K Erciyas K Sezer U domized split-mouth clinical trial J Saglam M Kantarci A Dundar N 1 Bukhary R Wassell R Sidhu S et al. The Local Anaesthetic effect of a dental laser prior to cavity preparation a pilot volunteer study J. Oper Dent PMID Kranendonk A van der Reijden W van Winkelhoff A et al. The bactericidal effect of a Genius Nd YAG laser J. Int J Dent Hyg Yaneva B Firkova E Karaslavova E et al. Bactericidal effects of u- sing a fiber-less Er YAG laser system for treatment of moderate. Quintessence Int lasers on titanium. J Oral Maxillofac Surg et al. Comparative evaluation of the effects of different photoablative laser irradiation protocols on the. Photomed Laser Surg et al. Adjunctive Nd immunolog-. Lasers Med Sci et al. Clinical and biochemical effects of 810 nm diode laser as an adjunct to periodontal therapy a ran-. Photomed Laser Surg 2014 et al. Clinical and biochemical effects of diode laser as an adjunct to nonsurgical treatment of chronic periodontitis a randomized controlled clinical trial J. Lasers Med Sci Er YAG Nd YAG 37 J Pavone C Perussi LR de Oliveira GJ Nd YAG J. et al. Effect of Er Cr YSGG laser application in the treatment of experimental periodontitis J /

5 5 OL. Lasers Med Sci PMID Nevins ML Camelo M Schupbach P et al. Human clinical and histologic evaluation of laser-assisted new attachment procedure J. Int J Periodontics Restorative Dent Theodoro LH Caiado RC Longo M et al. Effectiveness of the diode laser in the treatment of ligature-induced periodontitis in rats a histopathological histometric and immunohistochemical study J. Lasers Med Sci PMID Chellini F1 Sassoli C Nosi D et al. Low pulse energy Nd YAG laser irradiation exerts a biostimulative effect on different cells of the oral microenvironment " an in vitro study" J. Lasers Surg Med Er Cr YSGG Lasers Med Sci J. PMID Almehdi A Aoki A Ichinose S et al. Histological and SEM analysis of root cementum following irradiation with Er YAG and CO 2 lasers J. Lasers Med Sci Miremadi S Cosyn J Schaubroeck D et al. Effects of root surface debridement using Er YAG Laser versus ultrasonic scaling-a SEM study J. Int J Dent Hyg Sgolastra F Severino M Petrucci A et al. Nd YAG laser as an adjunctive treatment to nonsurgical periodontal therapy a meta-analysis J. Lasers Med Sci Krohn-Dale I B e OE Enersen M et al. Er YAG laser in the treatment of periodontal sites with recurring chronic inflammation a 12-month randomized controlled clinical trial J. J Clin Periodontol Euzebio Alves VT de Andrade AK Toaliar JM et al. Clinical and microbiological evaluation of high intensity diode laser adjutant to non-surgical periodontaltreatment a 6-month clinical trial J. Clin Oral Investig Kelbauskiene S Baseviciene N Goharkhay K et al. One-year clinical results of Er Cr YSGG laser application in addition to scaling and root planing in patients with early to moderate periodontitis J. Lasers Med Sci Balasubramaniam AS Thomas LJ Ramakrishnanan T et al. Shortterm effects of nonsurgical periodontal treatment with and without use of diode laser 980 nm on serum levels of reactive oxygen metabolites and clinical periodontal parameters in patients with chronic periodontitis a randomized controlled trial J. Quintessence Int Soo L Leichter JW Windle J et al. A comparison of Er YAG laser and mechanical debridement for the non-surgical treatment of chronic periodontitis a randomized prospective clinical study J. J Clin Periodontol Dyer B Sung EC. Minimally invasive periodontal treatment using the Er Cr YSGG laser. A 2-year retrospective preliminary clinical study J. Open Dent J Er Cr YSGG J Dilsiz A Sevinc S. Trauma from instrumentation after non-surgical periodontal treatment with ultrasonic scalers and Nd YAG laser 15. Er Cr YSGG J. Acta Odontol Scand J. 29 Sawabe M Aoki A Komaki M et al. Gingival tissue healing following Er YAG laser ablation compared to electrosurgery in rats J. 30 Sanz-Moliner JD Nart J Cohen RE et al. The effect of an 810-nm diode laser on postoperative pain and tissue response after modified Widman flap surgery a pilot study in humans J. J Periodontol Gupta M Lamba AK Verma M et al. Comparison of periodontal open flap debridement versus closed debridement with Er Cr YS- GG laser J. Aust Dent J J. 32 Zingale J Harpenau L Chambers D et al. Effectiveness of root planing with diode laser curettage for the treatment of periodontitis J. J Calif Dent Assoc Myers TD. Laser s in dentistry J. J Am Dent Assoc Rastogi PK Lal N Garg N et al. Aesthetic management of gingival recession by root biomodification with carbon dioxide laser and subepithelial connective tissue graft with lateral repositioned flap technique J. BMJ Case Rep Orchardson R. Effect of pulsed Nd YAG laser radiation on action potential in isolated mammalian spinal nerves J. Lasers Surg Med Er YAG J Birang R Poursamimi J Gutknecht N et al. Comparative evaluation of the effects of Nd YAG and Er YAG laser in dentin hypersensitivity treatment J. Lasers Med Sci