MIH MIH. Molar-Incisor Hypomineralization MIH MIH MIH MIH MIH MIH. Atsuo SAKURAI, DDS. Seikou SHINTANI, DDS

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1 MIH MIH J Health Care Dent. 2014; 14: 6-12 Printed in Japan. All rights reserved Atsuo SAKURAI, DDS Seikou SHINTANI, DDS Prevalence, severity, and potential aetiological factors of Molar-Incisor Hypomineralization in Japanese children Molar Incisor Hypomineralization (MIH) is a wide range of amelogenesis disorder, including white spot, discoloration, and enamel defects. Causative agents are still unclear, and in Japan, the prevalence and distribution have not been investigated. To clarify the prevalence and severity of MIH among Japanese children, an epidemiological study was conducted in schoolchild population. The clinical examination of MIH was performed in 2121 Japanese schoolchildren. The prevalence of MIH was 11.9%. Only slight opacity or discolored region was observed in 76.6% of children with MIH. However, 49 children (23.4%) had a wide range of affected tooth surfaces or enamel defects and classified as severe MIH. Several studies reported that the prevalence of MIH was between 2.8% and 24.9%, and varied widely depending on countries and the criteria of MIH. Because in some MIH cases, even mildly affected surfaces sometimes cause the destruction of enamel, it is necessary that long-term observation and treatment are performed by skillful practitioners of pediatric dentistry. J Health Care Dent. 2014; 14: Depertment of Pediatric Dentistry, Tokyo Dental College , Misaki-cho, Chiyoda-Ku, Tokyo , Japan MIH dental examination survey fluoride gel Molar-Incisor Hypomineralization MIH MIH 1 MIH MIH MIH MIH

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5 10 SAKURAI et al. 9 MIH MIH MIH P Yes No Yes No Yes No Yes No Yes No Yes No P<0.05 MIH 11.9 MIH MIH MIH 8, 9 MIH 2 1 1/3 19 MIH /3 MIH MIH MIH 4, 10 MIH MIH 11, 17 MIH

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7 12 SAKURAI et al. MIH MIH 1 Garg N et al. Essentiality of early diagnosis of molar incisor hypominerali-zation in children and review of its clinical presentation, etiology and management. Int J Clin Pediatr Dent. 2012; 5: Weerheijm KL et al. Molar-incisir hypo-mineralization. Caries Res. 2001; 35: Weerheijm KL et al. Judgement criteria for molar incisor hypomineralisation (MIH1) in epidemiologic studies: a summary of the European meeting on MIH held in Athens, Eur J Paediatr Dent. 2003; 4: Cho SY et al. Molar incisor hypo-minaralization in Hong Kong Chinese children. Int J Paediatr Dent. 2008;18: ,. 5 Kukleva MP et al. Molar incisor hypomineralization in 7 to 14- year-old children in Plovdiv, Bulgaria an epide-miologic study. Folia Med (Plovdiv). 2008; 50: Preusser SE et al. Prevalence and severity of molar-incisorhypomineralisation in a region of Germany-a brief communi-cation. J Public Health Dent. 2007; 67: Parikh DR et al. Prevalence and characteristics of Molar Incisor Hypomineralisation (MIH) in the child population residing in Gandhinagar, Gujarat, India. EurArchPaediatrDent. 2012; 13: Jasulaityte L et al. Molar incisor hypo-mineralization: review and prevalence data from the study of primary school children in Kaunas/Lithuania. Eur Arch Paediatr Dent. 2007; 8: Lygidakis NA et al. Molar-incisor-hypo-mineralisation (MIH). Retrospective clinical study in Greek children. I. Prevalence and defect characteristics. Eur Arch Paediat Dent. 2008; 9: Kemoli AM. Prevalence of molar incisor hypomineralisation in six to eight year-olds in two rural divisions in Kenya. East Afr Med J.2008; 85: Ghanim A et al. Risk factors in the occurrence of molar-incisor hypomine-ralization amongst a group of Iraqi children. Int J Paediatr Dent. 2013; 23: Gaecia-Margarit M et al. Epidemiologic study of molar-incisor hypomineralization in 8-year-old Spanish children. Int J Paediatr Dent doi: /ipd Souza JF et al. Mola.r incisor hypo-mineralisation: possible aetiological factors in children from urban and rural areas. Eur Arch Paediatr Dent. 2012; 13: Sugiyama S. Mola-incisor hypominera-lization clinical case and expression rate at the age of 12. By te data of SUGIYAMA Dental Office. JHealthCareDent. 2008; 10: Laisi et al. Amoxicillin may cause molar incisor hypomineralization. J Dent Res. 88: , Kumazawa et al. Effect of single-dose amoxicillin on rat incisor odontogenesis: a morphological study. Clin Oral Investig. 2012; 16: Lygidakis NA et al. Molar-incisor-hypomineralisation (MIH). Retrospective clinical study in Greek children. II. Possible medical aetiological factors. Eur Arch Paediat Dent, 2008; 9: Kushu OO et al. Association of amoxicillin use and molar incisor hypomineralization in piglets: Visual and mineral density evaluation. Arch Oral Biol. 2013; 58: Stephen KW. Dentifrices: recent clinical findings and implications for use. Int Dent J. 1993; 43: European Academy of Paediatric Dentistry. Guidelines on the use of fluoride in children: an EAPD policy document. Eur Arch Paediatr Dent. 2009; 10: p 98-99, : ; 2011.