Leeds Dental Institute

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1 Leeds Dental Institute A Clinical Academic Centre Teaching the whole dental team Research Specialist services Restorative Dentistry Paediatric Dentistry Oral Surgery linked with Maxillofacial surgery Oral Medicine Oral Pathology Dental & Maxillofacial Radiology Orthodontics

2 Dental Teaching Hospitals The primary purpose of the dental teaching hospitals is to teach undergraduate dental students and provide their clinical training There is a symbiotic relationship between the Schools of Dentistry and their associated Dental Teaching Hospitals This provides an effective way of teaching a large number of dental students There are seven other large dental schools and dental teaching hospital in England plus one postgraduate school in London. A Dental Care Professional training school in Portsmouth and two small community based schools in Devon-Cornwall and East Lancashire In 2006 there was a move nationally to develop more outreach teaching in the community

3 148 dental chairs at the main Dental Hospital, 7 at Seacroft Hospital and 1 in Bexley wing 22 dental chairs in 3 outreach clinics in Leeds, Bradford and Hull LDI has 31 consultants providing specialist care predominantly for the population of Leeds but also for the wider Yorkshire region

4 Activity 80,000 patient 25,000 attendances are attendances a year plus for treatment with 15,000 attendances at our students ( not subject to three outreach clinics a the 18 week pathway) total of 95,000 In addition the LDI attendances a year performs treatment under Of the 80,000 seen at LDI, GA each year for 1,000 14,500 are new referrals children and 750 adults and 40,000 follow up undergoing oral surgery attendances (mostly for procedures treatment)

5 Funding SIFT (service increment for teaching) the Leeds Dental Institute received 10.2 million of SIFT funding per annum Income for commissioned specialist care - 6 million per annum Other income research, private students, other training programmes million per annum

6 Teaching

7 All under one roof Dentists Hygiene /Therapists Dental Technologists Dental Nurses Postgraduates

8 Training dental students Professionalism Teamworking Communication skills Basic Medical sciences Applied dental sciences Pre-clinical skills training Clinical practice Safe Beginner

9 2005

10

11

12

13

14

15 Year 1 Impression taking Local anaesthetic Periodontal instrumentation

16 Year 2 Simple Fillings

17 Year 3 Crowns Extractions Root Canal Treatment

18 Year 4 Paediatric dentistry Dentures

19 Year 5 Clinical Examinations Written Papers Portfolio 3 adult cases 1 child case Unseen Case Examination

20

21 Research

22 Basic Dental Science Research Clinical & Applied Dental Research Education Research & Scholarship DenTCRU Biomineralisation Biomaterials & Tissue Engineering Microbiology & Cell Biology Clinical & Applied Dental Public Health & Health Services Research grants total value of awards 25M; LDI share 7M In-house and cross-faculty laboratory facilities

23 DenTCRU The Wellcome Trust and University of Leeds-funded Dental Translational & Clinical Research Unit (DenTCRU) 6 chair unit Reception Laboratory Permanent support staff: Trials Manager Trials statistician 2 research nurses 2 laboratory technicians

24 OUR VISION To use interdisciplinary expertise to understand the fundamental mechanisms of oral and other diseases, particularly musculoskeletal, to improve treatment, restore function and address the needs for prevention. LDI and University of Leeds strategic priority: Translation of our findings for patient benefit

25 DENTISTRY & MUSCULOSKELETAL - CROSS- FACULTY INITIATIVES Wellcome Trust: Medical Engineering Centre in Regenerative Medicine 5y, 11M. In Dentistry, WELMEC is addressing degeneration of bones and teeth in an ageing population and exploiting ease of access to deliver innovative regenerative therapies and novel diagnostic methods. EPSRC Innovation & Knowledge Centre for Regenerative Medicine 6.2 M; 5 translational Professors including J. Kirkham. Development of innovative devices for skeletal tissue regeneration and repair, regenerative therapies and diagnostic methods; early validation of technical concept and commercial feasibility to reduce late failure and accelerate innovation NIHR Leeds Musculoskeletal Biomedical Research Unit Centre of excellence for translational research into individually targeted, patient-focused therapies across the musculoskeletal diseases EPSRC Doctoral Training Centre in Regenerative Medicine 5.2 M. 50 PhD students over 5 years

26 Interdisciplinary Biomineralisation research for patient benefit: * With A Aggeli, Chemistry Arg3 Gln1 Glu5 Glu7 Glu9 Gln11 C N C N Gln2 Phe4 Trp6 Phe8 Gln10 *Rational design of self assembling molecular biomimetic scaffolds Gene discovery in AI: Leeds has discovered more genes than rest of world put together Mouse models; recombinant proteins, structure function relationships, control of mineral growth Filling without Drilling Product in international clinical use Clinical trials at Leeds Cytoxicity testing In situ testing (teeth) Animal testing (bone)

27 Restorative Dentistry

28 What is Restorative Dentistry? The repair and preservation of teeth and gums Replacement of missing teeth

29 REFERRALS Primary Dental Care (GDP s) and GMP s Hospital Consultants Dental and Medical Consistently high and increasing number of referrals per year

30 PRIMARY ROLES Treatment Planning and Advice Service for General Dentists Treatment of Medically Compromised Patients Rehabilitation of Patients with Head and Neck Cancer Treatment of Patients with Complex Dental Needs

31 Developmental Defects Malformation of teeth and jaws Cleft lip and palate Missing teeth

32 SECONDARY ROLES Specialty Training Undergraduate Teaching Research

33 Complications of head and neck cancer treatment Surgery Chemo and Radiotherapy

34 KEY HOSPITAL INTERFACES Maxillofacial and head and neck surgery Clinical oncology Head and Neck MDT Facial prosthetics Cardiac Other dental specialities

35 OUTCOMES Function -Eating, speaking, appearance Pain-free Quality of life

36 Dental Services for Children

37 Consultant led Specialist dental services for children

38 Children who are afflicted with dental caries more deprived background Behaviour management issues Specialist behaviour management techniques Sedation General anaesthesia inter/cross disciplinary care requires an understanding of the medical condition and its impact on provision of dental treatment

39 Management of Complex Trauma in Children and Adolescents Provision of innovative treatments in a growing child based on world class research to give them the best long term quality of life POOR PROGNOSIS!!

40 Regenerative Endodontic Therapy Based on Stem Cell Technology to regenerate/repopulate the root canals of non vital (dead) teeth with new pulp tissue: Angiogenesis Neural Innervation

41 AUTOTRANSPLANTATION MULTIDISCIPLINARY CARE

42 Oral Medicine

43 Oral Medicine Concerned with the oral health care of patients with chronic recurrent and medically related disorders of the mouth and with their diagnosis and non-surgical management.

44 Oral Medicine Pain Salivary Gland Mucosa

45 Pain Oral Medicine

46 Oral Medicine Salivary Gland

47 Oral Medicine Salivary Gland

48 Mucosa Oral Medicine

49 Oral Medicine Pain Salivary Gland Mucosa

50 Orthodontics

51 Correction of severe dental malocclusions and dento-facial deformity

52 Interdisciplinary orthodontics Restorative Dentistry Oral & Maxillofacial Surgery Cleft Team Paediatric Dentistry Orthodontics Oral Surgery

53 Orthodontics & Orthognathic Surgery

54 Orthodontics & Cleft Care 1 in 700 live births Associated with over 300 syndromes Orthodontics integral to their care pathway and instrumental in Cleft research

55 Cleft Care Pathway 3-6 months Lip repair 18+ years months Palate repair 7-9 years Pre-Alveolar bone graft orthodontics years Definitive orthodontics Orthognathic surgery

56 Hypodontia Familial 5% of the UK population Missing teeth

57 Comprehensive Orthodontics Orthodontic treatment of referred patients with severe malocclusions Increased prominence of teeth Impacted teeth Previous trauma needing premolar transplants

58 Thank you for listening Any questions?

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