NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE Centre for Clinical Practice Surveillance Programme
|
|
- Cody Lindsey
- 5 years ago
- Views:
Transcription
1 NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE Centre for Clinical Practice Surveillance Programme Clinical guideline CG28: Depression in children and young people: identification and management in primary, community and secondary care Publication date September 2005 Previous review dates 2 year review: 2007 (no update) 5 year review: 2010 (no update) Surveillance report for GE October 2013 Key findings Potential impact on guidance Evidence identified from evidence update Evidence identified from literature search Feedback from Guideline Development Group Anti-discrimination and equalities considerations No update Rapid update Standard update Transfer to static list No Change review cycle Surveillance recommendation GE is asked to consider the proposal to update the guideline as a rapid update (using Guideline Updates standing committee). GE are asked to note that this yes to update proposal will not be consulted on. CG28 Depression in children, Surveillance review decision, October of 20
2 NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE Centre for Clinical Practice Surveillance Programme Surveillance review of CG28: Depression in children and young people: identification and management in primary, community and secondary care Background information Guideline issue date: year review: 2007 (no update) 5 year review: 2010 (no update) 8 year review: 2013 NCC: Mental Health Recommendation for Guidance Executive Main s from previous surveillance review 1. CG28 was previously reviewed for update in 2007 and At both review points, no new evidence was identified which would change the direction of guideline recommendations. The review recommendations at both review points was that the guideline should not be considered for an update. Eight year surveillance review 2. The Evidence Update on CG28: Depression in children (published June 2013) was used as the primary source of evidence for this surveillance review which considered new evidence since the last surveillance review (searches conducted August 2010). An additional literature search for randomised controlled trials and systematic reviews was carried out between January 2013 (the end of the search CG28 Depression in children, Surveillance review decision, October of 20
3 period for the Evidence Update) and August 2013 and relevant abstracts were assessed. Clinical feedback on the guideline was obtained from six members of the GDG (including the Chair) through a discussion at the Evidence Update Advisory Group meeting in March New evidence that may impact on recommendations was identified relating to two clinical areas within the guideline: Clinical area 1: Psychological interventions for mild depression recommendation Q: For children and young people who are depressed, does a psychological intervention when compared to standard care / wait-list control/ protocol driven clinical management/ another psychological intervention produce benefits/ harms on the specified outcomes? Evidence summary GDG/clinical perspective Impact Evidence identified from Evidence Update Classroom-based CBT in young people at high risk of depression A study identified Evidence Update indicated that delivery of a group CBT programme in schools may not reduce symptoms of depression 1. In addition, the study could not rule out a potential small clinical harm from classroombased CBT compared with usual school provision. Computerised CBT for young people with depressive symptoms One trial was identified for the Evidence Update which compared an interactive fantasy game designed to deliver CBT for the treatment of depression with usual care (counselling) for young people (12-19 year olds) 2. The results of the study indicated that computerised CBT was not inferior to usual care in the primary, per protocol analysis, as shown difference in mean reduction in Children s Depression Rating No GDG feedback was provided for this clinical area. New evidence is available which suggests that computerised delivery of CBT may be feasible and beneficial in children and young people with mild depression. Furthermore, there is evidence that has been published since the guideline was released indicating that group CBT delivered in a school setting may not reduce the symptoms of depression. This new evidence may enable modification of the current guideline recommendation for CBT in children and young people with mild depression which indicates that group CBT is recommended (in addition to other psychological therapies) and could be provided by appropriately trained professionals in primary care, schools, social services and the voluntary sector or in tier 2 CAMHS. CG28 Depression in children, Surveillance review decision, October of 20
4 Scale (CDRS-R) score, whilst there was a significantly higher remission rate with the computerised intervention compared with usual care. The Evidence Update concluded that computerised CBT may be a valid treatment option for young people with mild depression. Evidence identified from literature search Computerised CBT for young people with depressive symptoms The feasibility, acceptability and efficacy of a computerised CBT programme compared with a computer-administered attention placebo program with psychoeducational content for depressed adolescents was evaluated in an RCT 3. Adolescents treated with computerised CBT showed greater symptom improvement on CDRS- R scale than those in the control group. Clinical area 2: Pharmacological interventions for moderate to severe depression recommendations / / / Q: For children and young people who are depressed, does any antidepressant when compared to any psychological intervention produce benefits/ harms on the specified outcomes? Q: For children and young people who are depressed, does the combination of an antidepressant and a psychological intervention when compared to an antidepressant alone/ psychological intervention alone produce benefits/ harms on the specified outcomes? Evidence summary GDG/clinical perspective Impact Evidence identified from Evidence Update Three systematic reviews of pharmacological interventions for depression in children and young people (including a Cochrane review) were Several GDG members were consulted at the Evidence Update Advisory Group meeting in March 2013 whereby it was felt that the recommendations in the 2005 Since publication of the guideline new evidence for moderate to severe depression in children and young people has been published which has been meta-analysed in the systematic reviews outlined CG28 Depression in children, Surveillance review decision, October of 20
5 identified for the Evidence Update which compared: Psychological vs. antidepressant therapy o One Cochrane review carried out an analysis of antidepressant vs. psychological therapy indicating that antidepressant therapy was more effective as measured by Clinician Defined Remission although suicide ideation was greater 4 Combined antidepressant plus psychological therapy vs. psychological therapy o The Cochrane review found no significant difference in remission rates, dropouts or suicide ideation between combination therapy vs. antidepressants for major depressive disorder 4 Combined antidepressant plus psychological therapy vs. antidepressant therapy o Two systematic reviews found no significant differences between combination or antidepressant therapy for the following outcomes: remission rates, dropouts or suicide ideation 4 and depressive symptoms, suicidality or global improvement 5 o One systematic review found significant improvement in the combination group using the Children s guideline relating to antidepressant treatment for moderate to severe depression were too conservative. During guideline development the GDG were concerned about suicide ideation following treatment but now the consensus among the literature is that it is safer to treat with antidepressants rather than wait. As such, the GDG felt that the cumulative evidence now supports more rapid utilisation of fluoxetine for moderate to severe depression (sooner than the 12 weeks currently recommended in the guideline). in this section. The results of these studies suggest that the recommendations on pharmacological treatment for moderate to severe depression may need to be revised as new data indicates there may be little difference in efficacy between monotherapy with psychological or antidepressant treatment for moderate or severe depression although suicide ideation may be greater following antidepressant treatment. Furthermore, the additional benefit of adding CBT to antidepressant therapy compared with antidepressants alone may not be as significant as previously thought whilst clinical feedback from the GDG suggests that the literature supports more rapid utilisation of fluoxetine for moderate to severe depression (sooner than the 12 weeks currently recommended). Additionally, since publication of CG28, fluoxetine has been licensed for use in children and young people aged 8 years and older to treat moderate to severe major depression that is unresponsive to psychological therapy after 4 6 sessions, in combination with a concurrent psychological therapy. Overall, the new identified evidence could have implications on the sequencing and timing of antidepressant treatment for moderate to severe depression currently recommended. CG28 Depression in children, Surveillance review decision, October of 20
6 Global Assessment Scale but no significant difference compared with antidepressants on the Clinical Global Impression Scale or CDRS-R scale for major depressive disorder 6 Ongoing research 4. The IMPACT trial is an RCT of short-term psychoanalytic psychotherapy, CBT and specialist clinical care for children and young people with depression. The results of this trial have not been published at this time (the study is expected to be completed by 2016) therefore it is not possible to determine any potential impact on guideline recommendations. However, data from this trial may contribute towards the evidence base relating to management of depression in children and young people in future surveillance reviews. Anti-discrimination and equalities considerations 5. None identified. Implications for other NICE programmes 6. This guideline relates to a Quality Standard on depression in children (expected to publish September 2013). 7. None of the quality statements are likely to be affected proposed areas for update. Conclusion 8. Through the review of CG28 new evidence which may potentially change the direction of guideline recommendations was identified in the following areas: a. Psychological interventions for mild depression b. Pharmacological interventions for moderate to severe depression 9. For all other areas of the guideline no evidence was identified which would impact on recommendations. CG28 Depression in children, Surveillance review decision, October of 20
7 Surveillance recommendation 10. GE is asked to consider the proposal to update the guideline as a rapid update (using Guideline Updates standing committee). GE are asked to note that this yes to update proposal will not be consulted on. Mark Baker Centre Director Sarah Willett Associate Director Emma McFarlane Technical Analyst Centre for Clinical Practice October 2013 CG28 Depression in children, Surveillance review decision, October of 20
8 References 1. Stallard P, Sayal K, Phillips R et al. (2012) Classroom based cognitive behavioural therapy in reducing symptoms of depression in high risk adolescents: pragmatic cluster randomised controlled trial. BMJ 345:e Merry SN, Stasiak K, Shepherd M et al. (2012) The effectiveness of SPARX, a computerised self help intervention for adolescents seeking help for depression: randomised controlled non-inferiority trial. BMJ 344:e Stasiak K, Hatcher S, Frampton C et al. ( ) A Pilot Double Blind Randomized Placebo Controlled Trial of a Prototype Computer- Based Cognitive Behavioural Therapy Program for Adolescents with Symptoms of Depression. Behav.Cogn.Psychother Cox GR, Callahan P, Churchill R et al. (2012) Psychological therapies versus antidepressant medication, alone and in combination for depression in children and adolescents. Cochrane Database Syst.Rev. 11:CD Dubicka B, Elvins R, Roberts C et al. (2010) Combined treatment with cognitive-behavioural therapy in adolescent depression: metaanalysis. Br.J Psychiatry 197: Calati R, Pedrini L, and Alighieri S. (2011) Is cognitive behavioural therapy an effective complement to antidepressants in adolescents? A meta-analysis. Acta Neuropsychiatrica 23: CG28 Depression in children, Surveillance review decision, October of 20
9 Appendix 1 Decision matrix Surveillance and identification of triggers for updating CG28. The table below provides summaries of the evidence for key questions for which studies were identified. Conclusions from previous Do screening instruments for depression have an influence on detection of depression in children and young people? Through a focused search 34 studies relevant to the clinical question were identified. Studies focused on the diagnostic accuracy, reliability and validity of depression screening instruments and interview-based instruments. However, due to the heterogeneous nature of the studies, it was concluded that further research is necessary to confirm reliability, validity and clinical utility of screening instruments in children and young people. No: new evidence (two studies identified through literature search) supports current recommendations which state that healthcare professionals in primary care settings should be familiar with screening for mood disorders and should have regular access to specialist supervision and consultation. New evidence is consistent with guideline recommendations. How might services be organised to detect depression in children and young people? No No relevant evidence identified. What risk factors are associated with depression in children and young people? One study was identified through the high-level search which concluded that cognitive and familial factors predict No: risk factors (three studies identified through literature search) identified included female sex, poor inter-parental or adolescent-parent New evidence is consistent with guideline recommendations. CG28 Depression in children, Surveillance review decision, October of 20
10 those depressed youth who have high relationship, low socio-economic status, parental levels of hopelessness. This study was depression, low level of parental education and judged as not likely to impact on poor academic performance. These risk factors guideline recommendations. are broadly in line with those discussed in the guideline. For children and young people who are depressed, does any antidepressant when compared to placebo/ comparator drug, produce benefits/ harms on the specified outcomes? A meta-analysis, two systematic reviews and 9 RCTs were identified through the focused search. The reviews focusing on fluoxetine indicated that this drug is effective in reducing depression symptoms in both children and adolescents. The efficacy and safety of tricyclic antidepressants was unclear. The RCTs included escitalopram, atomexetine and venlafaxine which were not licensed for use in children in The Evidence Update highlighted that since publication of CG28, fluoxetine has been licensed for use in children and young people aged 8 years and older to treat moderate to severe major depression that is unresponsive to psychological therapy after 4 6 sessions, only in combination with a concurrent psychological therapy. In addition, at June 2013, citalopram, escitalopram, mirtazapine, paroxetine, sertraline and venlafaxine did not have UK marketing authorisation for use in depression in children and young people under the age of 18 years, and it is stated ir summary of product characteristics that they are either not recommended, or should not be used, for this indication. This was also the case at the time of guideline publication. Three tricyclic antidepressants are licensed for Generally new evidence is consistent with guideline recommendations. The extension of the fluoxetine license has been taken into consideration below. CG28 Depression in children, Surveillance review decision, October of 20
11 use in children over 12 years with depressive illness (doxepin, nortryptyline, trimipramine) however, evidence of effectiveness of these drugs in children and adolescents with depression remains unclear. For children and young people who are depressed, does any drug treatment (other than antidepressants) when compared to placebo/ comparator drug, produce benefits/ harms on the specified outcomes? No No relevant evidence identified. For children and young people who are depressed, does any antidepressant when compared to any psychological intervention produce benefits/ harms on the specified outcomes? For children and young people who are depressed, does the combination of an antidepressant and a psychological intervention when compared to an antidepressant alone/ psychological intervention alone produce benefits/ harms on the specified outcomes? The following trials were identified: TORDIA, TADS, ADAPT and TASA, a meta-analysis of these trials plus data from two older studies. No At this review point it was concluded that due to the small number of studies included in the analysis and the heterogeneity between studies (including variations in methodology), the generalisability of the results was limited. Evidence update Three systematic reviews (including a Cochrane review) are discussed in the Evidence Update which compare: Psychological vs. antidepressant o Cox An analysis of antidepressant vs. psychological treatment indicated antidepressant therapy was more effective as measured by Clinician Defined Remission although suicide ideation Following consideration of the identified meta-analyses, the Evidence Update concluded that there may be little difference in efficacy between monotherapy with psychological or antidepressant treatment for moderate or severe depression in the populations of young people studied (although there was some evidence to suggest a greater effect with antidepressant monotherapy as measured by clinician-defined remission). There is an increased risk of suicidal ideation from antidepressant monotherapy CG28 Depression in children, Surveillance review decision, October of 20
12 was greater Combination vs. antidepressant o Cox found no significant difference in remission rates, dropouts or suicide ideation between combination therapy vs. antidepressants for major depressive disorder o Dubika 2010 no significant benefit of combination vs. antidepressant alone for depressive symptoms, suicidality and global improvement after acute treatment or at follow-up o Calati found significant improvement in the combination group using the CGAS scale but no significant difference compared with antidepressants on the CGI-I or CDRS-R scale for major depressive disorder Combination vs. psychological o Cox found no significant difference in remission rates, dropouts or suicide ideation between combination therapy vs. antidepressants for major compared with psychological treatment alone. Combining CBT with antidepressants may be beneficial with regard to some measures of global functioning, although benefits in other measures are less clear. Combining CBT with antidepressants has not been convincingly shown to mitigate the risk of suicidal ideation from antidepressants. One RCT was included in the guideline which evaluated combination therapy (fluoxetine + CBT) vs. fluoxetine / fluoxetine + CBT vs. CBT and fluoxetine vs. CBT. The guideline currently recommends that children and young people with moderate to severe depression should be offered psychological therapy first-line. If there is no response after 3 months, an alternative psychological therapy or addition of antidepressant should be considered. Antidepressant treatment should only be given in combination with a psychological therapy* (recommendations / / / ). CG28 Depression in children, Surveillance review decision, October of 20
13 depressive disorder Calati R, Pedrini L, Alighieri S et al. (2011) Is cognitive behavioural therapy an effective complement to antidepressants in adolescents? A meta-analysis. Acta Neuropsychiatrica 23: Cox GR, Callahan P, Churchill R et al. (2012) Psychological therapies versus antidepressant medication, alone and in combination for depression in children and adolescents. Cochrane Database of Systematic Reviews issue 11: CD Dubicka B, Elvins R, Roberts C et al. (2010) Combined treatment with cognitive-behavioural therapy in adolescent depression: metaanalysis. British Journal of Psychiatry 197: Finally, studies were identified through the literature search which would not impact on guideline recommendations: Vitamin C as an adjuvant to fluoxetine (one RCT) Tricyclic drugs for depression in children and young people (one Cochrane review and Since publication of the guideline new evidence for major depressive disorder has been published in the TORDIA, TADS and ADAPT trials (and others) which has been meta-analysed in several systematic reviews. The results of these studies suggest that recommendations on pharmacological treatment for moderate to severe depression may need to be revised as new data indicates there may be little difference in efficacy between monotherapy with psychological or antidepressant treatment for moderate or severe depression although suicide ideation may be greater. Furthermore, the additional benefit of adding to CBT to antidepressant therapy compared with antidepressants alone may not be as significant as previously thought. Several GDG members were consulted at the Evidence Update Advisory Group meeting and, at that time, it was felt that the recommendations in the 2005 guideline relating to antidepressant treatment for moderate to severe depression were too conservative. At the time the GDG were concerned about CG28 Depression in children, Surveillance review decision, October of 20
14 one meta-analysis) Antidepressant-associated mood switching and mood elevation (two systematic reviews) Association between parent-child conflict and treatment outcomes (one RCT) Prevalence of subthreshold depression (two systematic reviews) suicide ideation following treatment but now the consensus among the literature is that it is safer to treat with antidepressants rather than wait. As such, the GDG feel that the cumulative evidence now supports more rapid utilisation of fluoxetine for moderate to severe depression (sooner than the 12 weeks currently recommended). *See note above under Q on antidepressant vs. placebo / antidepressant regarding drug licensing. For children and young people with psychotic depression, does any pharmacological intervention produce benefits/ harms on the specified outcomes? No No relevant evidence identified. For children and young people who are depressed, does an intervention other than psychological or pharmacological interventions produce benefits/ harms on the specified outcomes? No: one systematic review was identified through the literature search which investigated the efficacy of electroconvulsive therapy and the potential risks and complications of the procedure in depressed adolescents. No specific data was reported in the abstract therefore, it is not clear whether the results of this review would impact on the recommendations on electroconvulsive therapy. New evidence is unlikely to impact on current recommendations. CG28 Depression in children, Surveillance review decision, October of 20
15 For children and young people who are depressed, does a psychological intervention when compared to standard care / wait-list control/ protocol driven clinical management/ another psychological intervention produce benefits/ harms on the specified outcomes? Through the focused search 36 studies relevant to the clinical question were identified. Literature was identified evaluating self-help therapies, individual therapies (including cognitive behavioural therapy (CBT) and interpersonal therapy), group CBT and family therapies. The following areas were of particular relevance but it was felt that further research was required: No Evidence update One trial was identified for the Evidence Update which compared SPARX (Smart, Positive, Active, Realistic, X-factor thoughts) an interactive fantasy game designed to deliver CBT for the treatment of clinically significant depression with usual care (counselling) for young people (12-19 year olds). The results of the study indicated that SPARX was not inferior The Evidence Update concluded that computerised CBT may be a valid treatment option for young people with mild depression. A systematic review identified at the 5 year review point and a pilot RCT identified through the literature search conducted for the review of CG90 (study not identified by EU or surveillance search) also reported feasibility and efficacy of computerised CBT. CBT in schools One RCT results varied between schools / one systematic review schoolbased CBT had positive effect to usual care in the primary, per protocol analysis (participants completing at least 4 of the SPARX modules). However, there was a significantly higher remission rate (score less than 30 on the CDRS-R) with SPARX than usual care. Computerised CBT - One systematic review - all included studies reported reductions in clinical symptoms although satisfaction with treatment was moderate to high from both children and parents - high levels of drop out and non-completion reported Merry SN, Stasiak K, Shepherd M et al. (2012) The effectiveness of SPARX, a computerised self help intervention for adolescents seeking help for depression: a randomised controlled non-inferiority trial. British Medical Journal 344: e2598. In terms of group CBT for mild depression, one In terms of delivery of CBT in schools, the evidence based is mixed with a systematic review and RCT from the 2005 review indicating positive and variable effects respectively whilst a study discussed in the Evidence Update suggesting that delivery of a group CBT programme in schools may not reduce symptoms of depression. No relevant studies were identified through the literature search conducted between Jan Aug Taken together, new evidence is available which suggests that computerised delivery of CBT may be beneficial in children and CG28 Depression in children, Surveillance review decision, October of 20
16 RCT was identified which indicated that a group CBT programme delivered universally in a school setting, may not reduce symptoms of depression in young people at high risk of depression, and could increase reporting of symptoms. Stallard P, Sayal K, Phillips R et al. (2012) Classroom based cognitive behavioural therapy in reducing symptoms of depression in high risk adolescents: pragmatic cluster randomised controlled trial. British Medical Journal 345: e6058. Literature search The feasibility, acceptability and efficacy of a computerised cognitive behavioural therapy (ccbt) program compared with a computeradministered attention placebo program with psychoeducational content for depressed adolescents was evaluated in an RCT. Adolescents treated with ccbt showed greater symptom improvement on CDRS-R than those in the control group. Stasiak K, Hatcher S, Frampton C, Merry SN (2012). A Pilot Double Blind Randomized Placebo Controlled Trial of a Prototype young people with mild depression. Furthermore, there is evidence that has been published since the guideline was released indicating that group CBT delivered in a school setting may not reduce the symptoms of depression. This new evidence may enable modification of the current guideline recommendation for CBT in children and young people with mild depression: Mild depression (Recommendation ): o Individual non-directive supportive therapy, group CBT or guided self-help for a limited period (approximately 2 to 3 months). This could be provided by appropriately trained professionals in primary care, schools, social services and the voluntary sector or in tier 2 CAMHS N.B. The Evidence Update suggested that other studies on computerised CBT are available which were published prior to the search date of the Evidence Update but these studies were not prioritised and were not discussed specifically. CG28 Depression in children, Surveillance review decision, October of 20
17 Computer-Based Cognitive Behavioural Therapy Program for Adolescents with Symptoms of Depression. Behavioural and Cognitive Psychotherapy [Dec 20: 1-17 Epub ahead of print] Finally, studies were identified through the literature search on the following psychological interventions but the results of these studies currently would not impact guideline recommendations: Attachment based family therapy (one study) Feasibility of delivering school-based prevention programme (one systematic review) Short-term psychodynamic psychotherapy (one meta-analysis) Multifamily psychoeducational psychotherapy (one RCT) Behavioural intervention (one RCT) Parent-child interaction therapy (one systematic review) CBT (three RCTs) Primary care provider engagement (one RCT) For a psychological intervention that works, are [outcomes] correlated with any characteristics of the therapist/ service user? CG28 Depression in children, Surveillance review decision, October of 20
18 No: one RCT focusing on a modular approach to therapy was reported in the Evidence Update but it was concluded that further research in a UK or European setting is required before considering whether there would be an impact on the guideline. New evidence is unlikely to impact on guideline recommendations. For children and young people who are undiagnosed but at high risk of depression, does self-help or other psychological interventions when compared to standard care alone, produce benefits/ harms on the specified outcomes? Several studies, including RCTs and systematic reviews, focused on selfhelp therapies for depression. Most studies evaluated internet-based therapies. The results of the studies were considered unlikely to impact on guideline recommendations. No: additional studies on internet-based selfhelp interventions were identified. Although the use of the internet is not specifically included in the recommendations, Appendix K of the guideline (common forms of self-help) describes the use of the internet for self-help interventions. New evidence is unlikely to impact on current recommendations. For children and young people who are undiagnosed but at high risk of depression, does family support/ parental education when compared to standard care, produce benefits/ harms on the specified outcomes? Three studies were identified through the high-level search which assessed family therapy and family support in children and young people at high-risk of depression. The results of the studies supported guideline recommendations. No No relevant evidence identified. For children and young people who are depressed, does self-help when compared to standard care, produce benefits/ harms on the specified outcomes? Studies on exercise (one study) and relaxation (one study) were identified. No: one small study was identified through the literature search which demonstrated a small New evidence is consistent with guideline recommendations. CG28 Depression in children, Surveillance review decision, October of 20
19 The results of the studies were significant effect of physical activity on considered unlikely to impact on depression which supports the current guideline recommendations. recommendation which states that advice should be given on the benefits of regular exercise. For children and young people who are depressed, does family support/ parental education when compared to standard care, produce benefits/ harms on the specified outcomes? No: a post-hoc analysis was identified Evidence Update which concluded that a range of individual characteristics and family contextual issues may moderate the effects of treatment, consistent with CG28. New evidence is consistent with guideline recommendations. For children and young people who are depressed, is there any subgroup for which inpatient treatment produces benefits on the specified outcomes? No No relevant evidence identified. For children and young people who are depressed, is there any subgroup in which social/ environmental treatments alone produce benefits on the specified outcomes? (e.g., in young people who are experiencing bullying or abuse)? No No relevant evidence identified. For children and young people who are depressed, do antidepressant drugs, when compared to standard care, prevent relapse in the long term when prescribed in the recommended maintenance dose range? No No relevant evidence identified. For children and young people who are depressed, how long should antidepressant drug treatment be continued for prevention of relapse? No No relevant evidence identified. For children and young people who are depressed, do psychological interventions, when compared to standard care, prevent relapse in the long term? No No relevant evidence identified. CG28 Depression in children, Surveillance review decision, October of 20
20 What are the key elements of care, particularly service organisations and interfaces between services, to maximise patient's outcomes? No No relevant evidence identified. CG28 Depression in children, Surveillance review decision, October of 20
Oxleas CAMHS Dr Joanna Sales Clinical Director. Adolescent problems: Depression Deliberate Self Harm Early Intervention in Psychosis
Oxleas CAMHS Dr Joanna Sales Clinical Director Adolescent problems: Depression Deliberate Self Harm Early Intervention in Psychosis PREVALENCE At any one time, the estimated number of children and young
More informationDepression in children: identification and management of depression in children and young people in primary, community and secondary care
Depression in children: identification and management of depression in children and young people in primary, community and secondary care NICE guideline First consultation, November 2004 If you wish to
More informationDepartment of Psychiatry & Behavioral Sciences. University of Texas Medical Branch
Depression in Childhood: Advances and Controversies in Treatment Karen Dineen Wagner, MD, PhD Marie B. Gale Centennial Professor & Vice Chair Department of Psychiatry & Behavioral Sciences Director, Division
More informationNATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE Scope for Partial Update
NATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE Scope for Partial Update 1 Guideline title Anxiety: management of generalised anxiety disorder in adults in primary, secondary and community care (update)
More informationCONTEXTUALIZING DEPRESSION CLINICAL PRACTICE GUIDELINES. Darren Courtney and Emma McCann
CONTEXTUALIZING DEPRESSION CLINICAL PRACTICE GUIDELINES Darren Courtney and Emma McCann Conflicts of Interest Dr. Courtney s research is funded by the Cundill Centre for Child and Youth Depression; he
More informationSurveillance report Published: 26 October 2017 nice.org.uk
Surveillance report 2017 Bipolar disorder: assessment and management (2014) NICE guideline Surveillance report Published: 26 October 2017 nice.org.uk NICE 2017. All rights reserved. Subject to Notice of
More informationSurveillance report Published: 13 April 2017 nice.org.uk. NICE All rights reserved.
Surveillance report 2017 Antisocial behaviour and conduct disorders in children and young people: recognition and management (2013) NICE guideline CG158 Surveillance report Published: 13 April 2017 nice.org.uk
More informationAntidepressants (Tricyclic Antidepressants, Selective Serotonin Reuptake Inhibitors) in children 6-12 years of age with depressive episode/disorder
updated 2012 Antidepressants (Tricyclic Antidepressants, Selective Serotonin Reuptake Inhibitors) in children 6-12 years of age with depressive episode/disorder Q10: Are antidepressants (Tricyclic antidepressants
More informationSurveillance report Published: 8 June 2017 nice.org.uk. NICE All rights reserved.
Surveillance report 2017 Antenatal and postnatal mental health: clinical management and service guidance (2014) NICE guideline CG192 Surveillance report Published: 8 June 2017 nice.org.uk NICE 2017. All
More informationPsychological and Psychosocial Treatments in the Treatment of Borderline Personality Disorder
Psychological and Psychosocial Treatments in the Treatment of Borderline Personality Disorder The Nice Guidance for the Psychological and Psychosocial treatment of Borderline Personality Disorder (BPD)
More informationNational Institute for Health and Care Excellence
National Institute for Health and Care Excellence 4-year surveillance (2017) Bipolar disorder (2014) NICE guideline CG185 Appendix B: stakeholder consultation comments table Consultation dates: 10 to 24
More informationTreatment of Major Depression In Adolescents. Ian M Goodyer OBE MD FRCPsych FMedSci University of Cambridge
Treatment of Major Depression In Adolescents Ian M Goodyer OBE MD FRCPsych FMedSci University of Cambridge DSM: Unipolar Major Depression Irritability/anger Depressed mood Anhedonia Cognitive disturbance
More informationClinical guideline Published: 28 October 2009 nice.org.uk/guidance/cg90
Depression in adults: recognition and management Clinical guideline Published: 28 October 2009 nice.org.uk/guidance/cg90 NICE 2017. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-ofrights).
More informationBackground. Population/Intervention(s)/Comparison/Outcome(s) (PICO) Brief structured psychological treatment
updated 2012 Brief structured psychological treatment Q 3: Is brief, structured psychological treatment in non-specialist health care settings better (more effective than/as safe as) than treatment as
More informationClinical guideline Published: 28 October 2009 nice.org.uk/guidance/cg91
Depression in adults with a chronic physical health problem: recognition and management Clinical guideline Published: 28 October 2009 nice.org.uk/guidance/cg91 NICE 2018. All rights reserved. Subject to
More informationAT RISK MENTAL STATES IN PSYCHOSIS AND SCHIZOPHRENIA IN CHILDREN AND YOUNG PEOPLE
AT RISK MENTAL STATES IN PSYCHOSIS AND SCHIZOPHRENIA IN CHILDREN AND YOUNG PEOPLE Topic AT RISK MENTAL STATES IN PSYCHOSIS AND SCHIZOPHRENIA IN CHILDREN AND YOUNG PEOPLE Scope 4.3.1 (a) Review question(s)
More informationCommon mental health disorders
Common mental health disorders Identification and pathways to care Issued: May 2011 NICE clinical guideline 123 guidance.nice.org.uk/cg123 NICE has accredited the process used by the Centre for Clinical
More informationSPARX Fact sheet. SPARX is not designed for young people who: o Experience severe depression o At high risk of self-harm or suicide
SPARX Fact sheet What is SPARX? SPARX has been selected as an online e-therapy tool to be rolled out through Initiative 4 of the Prime Minister's Youth Mental Health Project SPARX is designed for all young
More informationIs Depression management getting you down? G. Michael Allan Director Programs and Practice Support, CFPC Professor, Family Med, U of A
Is Depression management getting you down? G. Michael Allan Director Programs and Practice Support, CFPC Professor, Family Med, U of A Faculty/Presenter Disclosures Faculty: Mike Allan Salary: College
More informationDepression in adults: treatment and management
1 2 3 4 Depression in adults: treatment and management 5 6 7 8 Appendix V3: recommendations that have been deleted of changed from 2009 guideline Depression in adults: Appendix V3 1 of 22 1 Recommendations
More informationCH 4: Antidepressants among adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective.
CH 4: Antidepressants among adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective. SCOPING QUESTION: Are antidepressants (specifically, tricyclic
More information#CHAIR2016. September 16 17, 2016 The Biltmore Hotel Miami, FL. Sponsored by
#CHAIR2016 September 16 17, 2016 The Biltmore Hotel Miami, FL Sponsored by Depression in Children and Adolescents Karen Dineen Wagner, MD, PhD University of Texas Medical Branch Galveston, TX Karen Dineen
More informationEvidence profile. Brief Structured Psychological treatment.doc. Background on the scoping question
Evidence profile Q3: Is brief, structured psychological treatment in non-specialist health care settings better (more effective than/as safe as) than treatment as usual in people with depressive episode/disorder?
More informationRevised Standards. S 1a: The service routinely collects data on age, gender and ethnicity for each person referred for psychological therapy.
Revised Standards S 1a: The service routinely collects data on age, gender and ethnicity for each person referred for psychological therapy. S1b: People starting treatment with psychological therapy are
More informationMajor Depressive Disorder (MDD) in Children under Age 6
in Children under Age 6 Level 0 Comprehensive assessment. Refer to Principles of Practice on page 5. Level 1 Psychotherapeutic intervention (e.g., dyadic therapy) for 6 to 9 months; assessment of parent/guardian
More informationIs Depression management getting you down? G. Michael Allan Director Programs and Practice Support, CFPC Professor, Family Med, U of A
Is Depression management getting you down? G. Michael Allan Director Programs and Practice Support, CFPC Professor, Family Med, U of A Faculty/Presenter Disclosures Faculty: Mike Allan Salary: College
More informationDepression in adults: treatment and management
Depression in adults: treatment and management NICE guideline: short version Draft for consultation, July 0 This guideline covers identifying, treating and managing depression in people aged and over.
More informationDepression: selective serotonin reuptake inhibitors
Depression: selective serotonin reuptake inhibitors Selective serotonin reuptake inhibitors (SSRIs) are considered first-line treatment for the majority of patients with depression. citalopram and fluoxetine
More informationDocument Title Pharmacological Management of Generalised Anxiety Disorder
Document Title Pharmacological Management of Generalised Anxiety Disorder Document Description Document Type Policy Service Application Trust Wide Version 1.1 Policy Reference no. POL 201 Lead Author(s)
More informationClinical guideline Published: 28 October 2009 nice.org.uk/guidance/cg90
Depression in adults: recognition and management Clinical guideline Published: 28 October 2009 nice.org.uk/guidance/cg90 NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-ofrights).
More informationDepression: management of depression in primary and secondary care
Issue date: December 2004, with amendments April 2007 Quick reference guide (amended) Depression: management of depression in primary and secondary care Amendment of recommendations concerning venlafaxine:
More informationMajor Depressive Disorder (MDD) in Children under Age 6
in Children under Age 6 Level 0 Comprehensive assessment. Refer to Principles of Practice on page 6. Level 1 Psychotherapeutic intervention (e.g., dyadic therapy) for 6 to 9 months; assessment of parent/guardian
More informationThey are updated regularly as new NICE guidance is published. To view the latest version of this NICE Pathway see:
in children and young people: recognition, detection, risk profiling and NICE Pathways bring together everything NICE says on a topic in an interactive flowchart. NICE Pathways are interactive and designed
More informationEffective Date: 5/28/2014 Version: 2.0 (Revised: 10/12/2015) Approval By: CCC Clinical Delivery Steering Planned Review Date: (04/47/2017)
Protocol Title: Depression & Generalized Anxiety Disorder Effective Date: 5/28/2014 Version: 2.0 (Revised: 10/12/2015) Approval By: CCC Clinical Delivery Steering Planned Review Date: (04/47/2017) Group
More informationIlluminating the Black Box: Antidepressants, Youth and Suicide
Illuminating the Black Box: Antidepressants, Youth and Suicide David H. Rubin, M.D. Executive Director, MGH Psychiatry Academy Director, Postgraduate Medical Education Director, Child and Adolescent Psychiatry
More informationBRIEF SUMMARY CONTENT
Page 1 of 17 Brief Summary GUIDELINE TITLE Depression. The treatment and management of depression in adults. BIBLIOGRAPHIC SOURCE(S) National Collaborating Centre for Mental Health. Depression. The treatment
More informationThe treatment of postnatal depression: a comprehensive literature review Boath E, Henshaw C
The treatment of postnatal depression: a comprehensive literature review Boath E, Henshaw C Authors' objectives To evalute treatments of postnatal depression. Searching MEDLINE, PsycLIT, Sociofile, CINAHL
More informationResearch Bulletin. Treating adolescents experiencing depression What aspects of cognitive behaviour therapy matter most?
Research Bulletin Treating adolescents experiencing depression What aspects of cognitive behaviour therapy matter most? ISSUE 08 Cognitive behaviour therapy (CBT) is recommended as a first-line treatment
More informationNATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE Centre for Clinical Practice
NATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE Centre for Clinical Practice Review of Clinical Guideline (CG54) - Urinary tract infection in children Background information Guideline issue date:
More informationThey are updated regularly as new NICE guidance is published. To view the latest version of this NICE Pathway see:
Step 3: GAD with marked functional impairment or that has not improved after step 2 interventionsentions bring together everything NICE says on a topic in an interactive flowchart. are interactive and
More informationThey are updated regularly as new NICE guidance is published. To view the latest version of this NICE Pathway see:
bring together everything NICE says on a topic in an interactive flowchart. are interactive and designed to be used online. They are updated regularly as new NICE guidance is published. To view the latest
More informationThe legally binding text is the original French version TRANSPARENCY COMMITTEE. Opinion. 1 October 2008
The legally binding text is the original French version TRANSPARENCY COMMITTEE Opinion 1 October 2008 EFFEXOR SR 37.5 mg prolonged-release capsule B/30 (CIP: 346 563-3) EFFEXOR SR 75 mg prolonged-release
More informationKEY MESSAGES. It is often under-recognised and 30-50% of MDD cases in primary care and medical settings are not detected.
KEY MESSAGES Major depressive disorder (MDD) is a significant mental health problem that disrupts a person s mood and affects his psychosocial and occupational functioning. It is often under-recognised
More informationRecommendation 1: Diagnosis of Generalized Anxiety Disorder (IΙΙ-2)
Final GAD RECOMMENDATIONS & EVIDENCE Recommendation 1: Diagnosis of Generalized Anxiety Disorder (IΙΙ-2) It is recommended for general practitioners and other Primary Health Care doctors to consider the
More informationImproving Access to Psychological Therapies and care pathways for depression in the UK
Improving Access to Psychological Therapies and care pathways for depression in the UK Psychotherapy in Europe: Disease management strategies for depression. Berlin, 23 February 2011 National Health Service
More informationSurveillance report Published: 6 April 2016 nice.org.uk. NICE All rights reserved.
Surveillance report 2016 Chronic obstructive pulmonary disease in over 16s: diagnosis and management (2010) NICE guideline CG101 Surveillance report Published: 6 April 2016 nice.org.uk NICE 2016. All rights
More informationClinical guideline Published: 25 May 2011 nice.org.uk/guidance/cg123
Common mental health problems: identification and pathways to care Clinical guideline Published: 25 May 2011 nice.org.uk/guidance/cg123 NICE 2017. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-ofrights).
More informationBEST in MH clinical question-answering service
Best Evidence Summaries of Topics in Mental Healthcare BEST in MH clinical question-answering service Question In adults with mental illness, particularly non-psychotic illnesses e.g. depression, anxiety
More informationOutline & Objectives
21/11/2017 ADHD Assessment and brief Intervention service: a multi-disciplinary perspective Kapil Sayal Outline & Objectives To be aware of the service context and development To understand these aspects
More informationInterests Register. Depression in children and young people Advisory Committee Publication Date: 10/04/2019
Depression in children and young people Advisory Committee Publication Date: 10/04/2019 Name Role with NICE Type of interest Description of interest Relevant dates Comments arose declared ceased Susan
More informationSummary of guideline for the. treatment of depression RANZCP CLINICAL PRACTICE GUIDELINES ASSESSMENT
RANZCP CLINICAL PRACTICE GUIDELINES Summary of guideline for the RANZCP CLINICAL PRACTICE GUIDELINES treatment of depression Pete M. Ellis, Ian B. Hickie and Don A. R. Smith for the RANZCP Clinical Practice
More informationThis guideline has not undergone previous surveillance.
Surveillance report 2016 Autism spectrum disorder in under 19s: support and management National Institute for Health and Care Excellence Surveillance programme Surveillance proposal consultation document
More informationProgramme Name: Climate Schools: Alcohol and drug education courses
STUDY REFERENCE: C/ADEPIS01 Programme Name: Climate Schools: Alcohol and drug education courses Contact Details: Nicola Newton, University of New South Wales, email: n.newton@unsw.edu.au Natasha Nair,
More informationGREATER MANCHESTER INTERFACE PRESCRIBING GROUP
GREATER MANCHESTER INTERFACE PRESCRIBING GROUP On behalf of the GREATER MANCHESTER MEDICINES MANAGEMENT GROUP SHARED CARE GUIDELINE FOR THE PRESCRIBING OF SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRIs)
More informationCommon mental health disorders: identification and pathways to care
Common mental health disorders: identification and pathways to care NICE guideline Draft for consultation, November 2010 If you wish to comment on this version of the guideline, please be aware that all
More informationPosttraumatic Stress Disorder Prevention and Treatment Guidelines Methodology and Recommendations
Posttraumatic Stress Disorder Prevention and Treatment Guidelines Methodology and Recommendations 1. Introduction 1.1. The updated ISTSS PTSD Prevention and Treatment Guidelines Methodology and Recommendations,
More informationDepression: Assessment and Treatment For Older Adults
Tool on Depression: Assessment and Treatment For Older Adults Based on: National Guidelines for Seniors Mental Health: the Assessment and Treatment of Depression Available on line: www.ccsmh.ca www.nicenet.ca
More informationAssessment and management of selfharm
Assessment and management of selfharm procedure Version: 1.1 Consultation Approved by: Medical Director, CAMHS Director, Director of Quality, Patient Experience and Adult services Medical Director Date
More informationConor K Farren. St Patricks University Hospital Trinity College Dublin Ireland
Conor K Farren St Patricks University Hospital Trinity College Dublin Ireland NICE: Background NICE set up in 1999 to reduce variation in availability and quality of NHS treatments. Does this by: Evidence
More informationCosting report: Lipid modification Implementing the NICE guideline on lipid modification (CG181)
Putting NICE guidance into practice Costing report: Lipid modification Implementing the NICE guideline on lipid modification (CG181) Published: July 2014 This costing report accompanies Lipid modification:
More informationMeta Analysis for Safety: Context and Examples at US FDA
Meta Analysis for Safety: Context and Examples at US FDA Mark Levenson, Ph.D. Division of Biometrics 7 Office of Biostatistics Office of Translational Sciences Center for Drug Evaluation and Research U.S.
More informationTreating Depression in Disadvantaged Women: What is the evidence?
Treating Depression in Disadvantaged Women: What is the evidence? Megan Dwight Johnson, MD MPH Associate Professor Medical Director, UWMC Inpatient Psychiatry Department of Psychiatry and Behavioral Sciences
More informationTaking Care: Child and Youth Mental Health TREATMENT OPTIONS
Taking Care: Child and Youth Mental Health TREATMENT OPTIONS Open Learning Agency 2004 TREATMENT OPTIONS With appropriate treatment, more than 80% of people with depression get full relief from their symptoms
More informationAppendix C - Summary form
National Institute for Health and Clinical Excellence Appendix C - Summary form Single Techn Appraisal (STA) Agomelatine for the treatment of major depressive episodes Response to consultee and commentator
More informationSocial Anxiety Disorder
Social Anxiety Disorder Stakeholder Workshop Notes 4 th February 2011 1. Suggested guideline development group composition Are all the suggested members (and the numbers of each type of member) appropriate
More informationNATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE SCOPE
NATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE 1 Guideline title SCOPE Drug Misuse: opiate detoxification of drug misusers in the community, hospital and prison. 1.1 Short title Drug misuse detoxification
More informationAnnex. Scientific conclusions and grounds for refusal presented by the European Medicines Agency
Annex Scientific conclusions and grounds for refusal presented by the European Medicines Agency Scientific conclusions and grounds for refusal presented by the European Medicines Agency Overall summary
More informationNATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE Centre for Clinical Practice Surveillance Programme
NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE Centre for Clinical Practice Surveillance Programme Clinical guideline CG54: Urinary tract infection: diagnosis, treatment and long-term management of
More informationdepression in England: CLAHRC findings on current performance &
Management of severe and chronic depression in England: CLAHRC findings on current performance & NICE service models for the future Richard Morriss Professor of Psychiatry and Community Mental Health,
More informationGuidelines MANAGEMENT OF MAJOR DEPRESSIVE DISORDER (MDD)
MANAGEMENT OF MAJOR DEPRESSIVE DISORDER (MDD) Guidelines CH Lim, B Baizury, on behalf of Development Group Clinical Practice Guidelines Management of Major Depressive Disorder A. Introduction Major depressive
More informationThe treatment of suicidality in adolescents by psychosocial interventions for depression: A systematic literature review
627374ANP0010.1177/0004867415627374ANZJP ArticlesDevenish et al. research-article2016 Key Review The treatment of suicidality in adolescents by psychosocial interventions for depression: A systematic literature
More informationSurveillance report Published: 17 March 2016 nice.org.uk
Surveillance report 2016 Ovarian Cancer (2011) NICE guideline CG122 Surveillance report Published: 17 March 2016 nice.org.uk NICE 2016. All rights reserved. Contents Surveillance decision... 3 Reason for
More informationVolume 4; Number 5 May 2010
Volume 4; Number 5 May 2010 CLINICAL GUIDELINES FOR ANTIDEPRESSANT USE IN PRIMARY AND SECONDARY CARE Lincolnshire Partnership Foundation Trust in conjunction with Lincolnshire PACEF have recently updated
More informationEvaluation of the computer-based CBT programme pilot at rural community pharmacies in Gwynedd
Evaluation of the computer-based CBT programme pilot at rural community pharmacies in Gwynedd Authors: Gareth Holyfield (Principal Pharmacist, Public Health Wales) Steffan John (Community Pharmacist, Betsi
More informationNATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE SCOPE
NATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE 1 Guideline title SCOPE Psychosis and schizophrenia in children and young people: recognition and management 1.1 Short title Psychosis and schizophrenia
More informationAiming for recovery for patients with severe or persistent depression a view from secondary care. Chrisvan Koen
Aiming for recovery for patients with severe or persistent depression a view from secondary care Chrisvan Koen Kent and Medway NHS and Social care Partnership trust Persistent depressive disorder F34 Persistent
More informationReducing the Anxiety of Pediatric Anxiety Part 2: Treatment
Reducing the Anxiety of Pediatric Anxiety Part 2: Treatment Lisa Lloyd Giles, MD Medical Director, Behavioral Consultation, Crisis, and Community Services Primary Children s Hospital Associate Professor,
More informationNICE UPDATE - Eating Disorders: The 2018 Quality Standard. Dr A James London 2018
NICE UPDATE - Eating Disorders: The 2018 Quality Standard Dr A James London 2018 Background Estimated number of people aged 16 years or older with eating disorders in England Description Percentage of
More informationChapter 6 Psychoeducation for depression, anxiety and psychological distress: a meta-analysis
Chapter 6 Psychoeducation for depression, anxiety and psychological distress: a meta-analysis Published: Donker, T., Griffiths, K.M., Cuijpers, P., Christensen, H., 2009. Psychoeducation for depression
More informationLes «E-Therapies» en prévention du suicide : de quoi ont-elles l air, fonctionnent-elles et quelles sont les avenues pour la recherche?
Les «E-Therapies» en prévention du suicide : de quoi ont-elles l air, fonctionnent-elles et quelles sont les avenues pour la recherche? Professor Simon Hatcher The University of Ottawa What do they look
More informationGuidance on competencies for Paediatric Pain Medicine reviewed 2017
Guidance on competencies for Paediatric Pain Medicine reviewed 2017 Endorsed by: Contents Introduction A: Core competencies for practitioners in Pain Medicine Page 2 4 Appendix A: Curriculum 5 B: Competencies
More informationDiagnosis & Management of Major Depression: A Review of What s Old and New. Cerrone Cohen, MD
Diagnosis & Management of Major Depression: A Review of What s Old and New Cerrone Cohen, MD Why You re Treating So Much Mental Health 59% of Psychiatrists Are Over the Age of 55 AAMC 2014 Physician specialty
More informationWales Mental Health Primary Care (WaMH in PC) Bursary Application Form 2010
Wales Mental Health Primary Care (WaMH in PC) Bursary Application Form 2010 Proposal for: Pilot study of Telephone CBT for individuals experiencing common mental health problems in Swansea s Wellbeing
More informationEffectiveness of cognitive behavioural therapy in primary health care: a review
Family Practice 2011; 28:489 504 doi:10.1093/fampra/cmr017 Advance Access published on 9 May 2011 Ó The Author 2011. Published by Oxford University Press. All rights reserved. For permissions, please e-mail:
More informationObsessive-Compulsive Disorder Clinical Practice Guideline Summary for Primary Care
Obsessive-Compulsive Disorder Clinical Practice Guideline Summary for Primary Care CLINICAL ASSESSMENT AND DIAGNOSIS (ADULTS) Obsessive-Compulsive Disorder (OCD) is categorized by recurrent obsessions,
More informationNATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE. Centre for Clinical Practice
NATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE Centre for Clinical Practice Review of Clinical Guideline (CG3) Preoperative tests: the use of routine preoperative testes for elective surgery Background
More informationCosts: description and values Outcomes: description and values. Costs: Consultations with psychologists, psychiatrists, GPs
Appendix 16f: Evidence tables for economic studies High intensity psychological interventions for Generalised Anxiety Disorder Reference to included study Heuzenroeder L, Donnelly M, Haby MM, Mihalopoulos
More informationNATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE Centre for Clinical Practice
NATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE Centre for Clinical Practice Review consultation document Review of Clinical Guideline (CG78) Borderline Personality Disorder 1. Background information
More informationHow has acceptability of healthcare interventions been defined and assessed? An overview of Systematic Reviews
Academic excellence for business and the professions How has acceptability of healthcare interventions been defined and assessed? An overview of Systematic Reviews Mandeep Sekhon*, Martin Cartwright, &
More informationQUALITY ASSESSMENT (QA) MANUAL
QUALITY ASSESSMENT (QA) MANUAL RFP-NIH-NIMH 98-DS-0008 Treatment for Adolescents with Depression Study (TADS) Principal Investigator: John S. March, MD, MPH. Duke University Medical Center with Duke Clinical
More informationPsychological Therapies, Annual Report on the use of IAPT services: England 2013/14 EXPERIMENTAL STATISTICS
Psychological Therapies, Annual Report on the use of IAPT services: England 2013/14 EXPERIMENTAL STATISTICS Published 17 September 2014 We are the trusted national provider of high-quality information,
More informationTechnology appraisal guidance Published: 22 February 2006 nice.org.uk/guidance/ta97
Computerised cognitive behaviour therapy for depression and anxiety Technology appraisal guidance Published: 22 February 2006 nice.org.uk/guidance/ta97 NICE 2017. All rights reserved. Subject to Notice
More informationMedication Management. Dr Ajith Weeraman MBBS, MD (Psychiatry), FRANZCP Consultant Psychiatrist Epworth Clinic Camberwell 14 th March 2015
Medication Management Dr Ajith Weeraman MBBS, MD (Psychiatry), FRANZCP Consultant Psychiatrist Epworth Clinic Camberwell 14 th March 2015 1 Medication Management Objectives: 1. Principles of psycho-pharmacology
More informationOutline. Understanding Placebo Response in Psychiatry: The Good, The Bad, and The Ugly. Definitions
Outline Understanding Placebo Response in Psychiatry: The Good, The Bad, and The Ugly Michael E. Thase, MD Professor of Psychiatry Perelman School of Medicine University of Pennsylvania and Philadelphia
More informationNICE Clinical Guidelines recommending Family and Couple Therapy
Association for Family Therapy and Systemic Practice NICE Clinical Guidelines recommending Family and Couple Therapy August 2016 Compiled by: Dr Lucy Davis (Chartered and Clinical Psychologist/Trainee
More informationDisclosures. Learning Objectives. Psychopharmacology of Pediatric Anxiety and Depression 5/4/2017
Psychopharmacology of Pediatric Anxiety and Depression Susan Sharp, DO Clinical Assistant Professor of Child and Adolescent Psychiatry Kansas University Medical Center The Children's Mercy Hospital, 2017
More informationDate Event Description 26 February 2013 Amended Corrected result in abstract for suicidal ideation at six to nine months.
Psychological therapies versus antidepressant medication, alone and in combination for depression in children and adolescents Review information Review number: M05 Authors Georgina R Cox 1, Patch Callahan
More informationThe meaningful use of routine outcome monitoring in a low intensity service for children and young people with anxiety disorders and depression
School of Psychology and Clinical Language Sciences The meaningful use of routine outcome monitoring in a low intensity service for children and young people with anxiety disorders and depression Polly
More informationDoncaster Improving Access to Psychological Therapies (IAPT) Nurse Target September 2018 Dennis Convery
Doncaster Improving Access to Psychological Therapies (IAPT) Nurse Target September 2018 Dennis Convery Aims of the session To introduce the role and function of Doncaster IAPT (improving access to psychological
More informationNATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE SCOPE
NATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE 1 Guideline title SCOPE Neuropathic pain pharmacological management: the pharmacological management of neuropathic pain in adults in non-specialist
More information