ProFractional. ProFractional Therapy. Tunable Fractional Solution. Advanced Fractional Aesthetic Laser Surgery

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1 ProFractional-XC ProFractional ProFractional Therapy Tunable Fractional Solution Advanced Fractional Aesthetic Laser Surgery

2 ProFractional-XC is taking fractionated resurfacing to the next level. Todd Bessinger, M.D., Ph.D. Indications Deep wrinkles, fine lines, perioral and periorbital rhytides Post-traumatic, surgical and acne scars Actinic keratosis Pigmentation ProFractional Therapy Tunable Fractional Solution Dramatic Improvement in Wrinkles, Scars, Pigment, Tone and Texture Facial laser resurfacing has become a popular option for patients seeking to enhance the appearance of their skin. Unlike traditional laser peels, where effective results are associated with long periods of downtime, fractional technology offers a short-downtime solution for treating wrinkles, scars, pigment, and tone and texture of the skin. First generation fractional devices use non-ablative laser energy, leaving columns of necrotic debris in the tissue. They require multiple treatments and are not very effective on wrinkles or deep scars. New generation fractional devices use ablative wavelengths Er:YAG, CO2 or Er:YSGG. The results are more dramatic, but limited by the characteristics of the wavelength used. Sciton s unique Tunable Fractional Technology allows the user to emulate any ablative fractional technology thereby optimizing treatment depth, area coverage, and the ratio of ablation and thermal zone to each patient s condition, skin type, desired outcome and tolerance of downtime.

3 Technology & Benefits How ProFractional Therapy Works ProFractional Scan Pattern ProFractional Therapy is delivered by ProFractional and ProFractional XC laser modalities that use 2940 nm wavelength energy to create microablated channels deep in the dermal tissue, covering only a fraction of the total surface area and leaving the surrounding skin intact for faster healing and increased patient comfort. The wound-healing process produces fibroblasts that generate new collagen, plumping the skin and correcting skin imperfections. Due to efficient water absorption of the 2940 nm wavelength, ProFractional and ProFractional-XC can instantly eliminate the damaged tissue, accounting for effective results in just 1 to 3 single-pass treatments. The downtime from the procedure is very short, and patients can typically resume their normal activities and get back to work in 2 to 4 days after the treatment. Micro-ablated channels Tunable Treatment Settings for Optimal Outcomes Penetration Depth ProFractional Therapy allows you to select from a wide spectrum of treatment depths and densities, depending on the indications treated, the desired outcome and the patient s tolerance of downtime. Use superficial depth treatments for pigment, medium depth for fine lines and wrinkles, and deep depth for deep scars, acne scars or deep wrinkles. Depth adjustable from 25µ to 1500µ based on pulse duration and fluence Pigment Fine Lines/Wrinkles Deep Scars/Acne Scars and Wrinkles Coverage Density Use low-density area coverage for more conservative, shorter-downtime treatments, and higher-density area coverage for more efficacious results or to reduce the number of treatment sessions. Low density for short downtime treatments High density for more efficacious results

4 ProFractional-XC offers the coagulation capability to effect additional thermal damage, which actually mimics the CO2 treatment used in other devices. Jason Pozner, M.D. Ablation and Coagulation The present fractional ablative devices fall into one of the three major types: Er: YAG, CO2, and Er:YSGG. Each of these lasers delivers a fixed ratio of ablation and thermal damage determined by the characteristics of the wavelength. Traditional Er:YAG devices deliver pure ablation due to very efficient water absorption Er:YSGG and CO2 can deliver ablation only in conjunction with thermal injury ProFractional Therapy allows each patient to receive an optimal ratio of ablation and thermal zone based on their condition and tolerance of downtime. It is not limited by the wavelength used. Laser energy is delivered in a short pulse for tissue ablation, immediately followed by a user-controlled long pulse to create the selected thermal zone. It is the only fractional laser with this unique ability to: Turn the heat on for more collagen production or off to safely treat any skin type I VI Ablation Threshold Ablation Coagulation Control the amount of heat delivered independent of the ablation depth No Coag Coag Level 1 Coag Level 2 Coag Level 3 Energy Energy Energy Energy Pulse Width Pulse Width Pulse Width Pulse Width Emulate Other Fractional Technologies By changing the exposure time for heating, ProFractional Therapy emulates the amount of ablation and thermal damage produced by other laser wavelengths. With Sciton s tunable fractional resurfacing you don t need to choose between the three different technologies Er:YAG, Er:YSGG, or CO2 you have them all in one system. Er:YAG Er:YSGG CO2 ProFractional-XC with Tunable Thermal Zone

5 Modular Platform I use a lot of combination therapies in my practice. That makes up probably 90 percent of what I do. Denise Baker, M.D. ProFractional Therapy ThermaScan ProFractional-XC ProFractional ClearScan PROFILE Modules Combination Treatments BBL /SkinTyte Contour TRL w/ MicroLaserPeel There is nothing you can t do with this system! Jason Pozner, M.D. Increase Revenue and Eliminate Obsolescence ProFractional and ProFractional-XC are available as modules on the PROFILE multi-application platform providing the user with a fl exible and cost-effective solution. All modules come with unlimited pulses under warranty, no consumable items and no hidden costs. In addition to ProFractional and ProFractional-XC, PROFILE can accommodate three other laser modules and the Broadband Light module offering skin resurfacing, scar revision, wrinkle reduction, acne treatment, hair removal, pigmented and vascular lesion treatment and various combination procedures on the same platform. New technologies are added to the PROFILE as they become available. Increase your return-on-investment and eliminate obsolescence with the PROFILE modular platform.

6 Combination Treatments Combination treatments using Sciton s PROFILE platform enable enhanced results without increasing downtime, can reduce the number of treatment sessions, and allow the practitioner to offer an individualized treatment to each patient. Some popular examples of combination therapy include: ProFractional + MLP ProFractional plus MLP (MicroLaserPeel ) Remove superfi cial skin lesions, irregularities and dyscromias with MicroLaserPeel superfi cial resurfacing and correct deep scars and wrinkles with ProFractional in the same treatment session. ProFractional + BBL ProFractional plus BBL (Broadband Light) Remove pigmented and vascular lesions with Broadband Light and correct deep scars and wrinkles with ProFractional in the same treatment session. ProFractional + ST ProFractional plus ST (SkinTyte ) Treat skin laxity with SkinTyte and correct deep scars and wrinkles with ProFractional in the same treatment session. All these treatment options and more are available on the PROFILE platform. ProFractional / ProFractional-XC MicroLaserPeel BBL (Broadband Light) SkinTyte

7 Before and After Clinical Results It s pretty hard to find a device that gives you a better improvement than ProFractional Kent Remington, M.D., FACS., FRCP ProFractional Therapy Combination Therapy ProFractional - Acne Scars Photos courtesy of Todd Bessinger, M.D., Ph.D. ProFractional and MicroLaserPeel - Acne Scars Photos courtesy of Adam Baker, M.D. ProFractional-XC - Pigment and Acne Scars Photos courtesy of Kent Remington, M.D. ProFractional and BBL - Acne Scars Photos courtesy of Denise Baker, M.D. ProFractional - Wrinkles Photos courtesy of Michael Gold, M.D. ProFractional-XC and BBL - Pigment and Wrinkles Photos courtesy of Todd Bessinger, M.D.

8 Specifications ProFractional and ProFractional-XC ProFractional ProFractional-XC Wavelength Er:YAG 2940 nm Er:YAG 2940 nm Ablation depth µm µm Density % 5.5% or 11% Spot size 250 µm 430 µm Scanned Area 6 x 6 to 20 x 20 mm 6 x 6 to 20 x 20 mm Treatment speed Average Fast Available on PROFILE platform Optional user-controlled thermal coagulation and emulates other fractional technology 925 Commercial Street, Palo Alto, California Phone: Sciton, Inc. All rights reserved. Sciton, PROFILE, ProFractional, ProFractional-XC, ThermaScan, ClearScan, BBL, SkinTyte, MicroLaserPeel, Contour TRL are registered trademarks and trademarks of Sciton Inc Rev Rev 1