Histopathology: skin pathology
|
|
- Geoffrey Wade
- 5 years ago
- Views:
Transcription
1 Histopathology: skin pathology These presentations are to help you identify, and to test yourself on identifying, basic histopathological features. They do not contain the additional factual information that you need to learn about these topics, or necessarily all the images from resource sessions. This presentation contains images of basic histopathological features of common skin pathologies. Before viewing this presentation you are advised to review relevant histology, sections on inflammation, healing, neoplasia, psoriasis and dermatitis in a pathology textbook, relevant lecture notes, relevant sections of a histopathology atlas and the histopathology power point presentations on healing and neoplasia. Copyright University of Adelaide 2011 Med 3: skin cases semester 1
2 Skin, solar elastosis. Note the greypurple discolouration (it should be eosinophilic) of the dermal connective tissue (black star). This results from chronic sun damage. Age and sun related changes to the dermis, particularly to the elastic tissue component, lead to wrinkling.
3 Solar/actinic keratosis (epidermal dysplasia caused by sun damage) left side of black line, normal epidermis right side. Note that in the solar keratosis there is disorganization of keratinocytes and some keratinocytes have enlarged nuclei, the stratum granulosum is absent and nuclei are retained in the stratum corneum (parakeratosis). This results from more rapid proliferation of cells with insufficient time for normal differentiation as they ascend from the basal layer. The blue line denotes the approx. location of the epidermal basement membrane.
4 Squamous cell carcinoma (outlined by blue lines) invading through dermis into subcutaneous tissue (very low power view). Origin from the epidermis is not always readily seen. The tumour comprises invasive islands of cells that appear eosinophilic on low power due to their relatively low N:C ratios as many are similar to cells of the stratum spinosum. The dark discolouration (predominant staining with haematoxylin) in the dermis at the edges of the lesion is due to a chronic inflammatory cell infiltrate. Black stars: epidermis. (From Australian Cancer Society collection 1991)
5 Squamous cell carcinoma. High power view of tumour cells (tumour cells only, the invasive nature of the cells cannot be seen here). The cells show cytological features of malignancy: nuclear enlargement, pleomorphism, prominent nucleoli. These cells are mostly relatively well differentiated being similar to cells of the stratum spinosum with abundant eosinophilic cytoplasm and intercellular bridges (black arrows). However, some cells focally are differentiating further (black star), becoming flattened and keratinising and their nuclei are undergoing pyknosis, similar to more superficial squamous cells.
6 Squamous cell carcinoma. High power view of tumour cells. The cells show cytological features of malignancy: nuclear enlargement, pleomorphism, prominent nucleoli. These cells are mostly well differentiated being similar to cells of the stratum spinosum with abundant eosinophilic cytoplasm and intercellular bridges (black arrow). However, some cells focally are differentiating further, becoming flattened and fully keratinising, forming a keratin pearl (black star).
7 Squamous cell carcinoma, medium power view. The cells show cytological features of malignancy: nuclear enlargement, pleomorphism, prominent nucleoli. However, these cells are fairly poorly differentiated. It is difficult to tell that they are squamous. They still have some eosinophilic cytoplasm but there is no keratinisation. Intercellular bridges are difficult to distinguish at this power.
8 Basal cell carcinoma (outlined by blue lines) invading through dermis into subcutaneous tissue (very low power view). The tumour comprises invasive islands of cells that appear basophilic on low power due to their high N:C ratios as many are similar to cells of the stratum basale. Black stars: epidermis. (From Australian Cancer Society Collection, 1991)
9 Basal cell carcinoma (medium power). Islands of cells (black stars) originating from epidermis invading into dermis. Cells at the edges of the islands are arranged in a palisade pattern (peripheral palisading) and have high N:C ratios similar to cells of the stratum basale. Epidermis over the tumour is beginning to ulcerate (blue star) as is common in these lesions (which are sometimes referred to as rodent ulcers). A chronic inflammatory cell infiltrate is seen in the surrounding dermis. Red star: intact epidermis
10 Tumour Stroma Basal cell carcinoma (high power). The cells at the edge of the tumour are arranged in a palisade pattern (peripheral palisading - black arrows) and have high N:C ratios similar to cells of the stratum basale.
11 Normal epidermis and papillary dermis (high power). Scattered melanocytes (black arrows) are easily seen at the dermo-epidermal junction.
12 Normal epidermis and papillary dermis (high power). Melanin stains black in this Masson Fontana stain. Scattered melanocytes (black arrows) are easily seen. Note how most of the melanin has been transferred to keratinocytes.
13 Common types of benign melanocytic naevi generally contain bland naevus cells that are arranged as nests at the dermoepidermal junction and/or nests or sheets in the dermis. The image demonstrates a compound melanocytic naevus with both junctional (black arrows) and dermal (red stars) naevus cells. Note the prominent pigmentation which gives these lesions their brown colour macroscopically.
14 Invasive malignant melanomas contain melanocytes that are generally arranged as nests at the dermoepidermal junction and/or nests or sheets in the dermis. The cells however are atypical. In situ melanomas contain only a junctional component i.e. no invasive dermal component. The image demonstrates an invasive malignant melanoma. Black arrows: junctional nests of malignant melanocytes. Red stars: malignant melanocytes invading the dermis. In malignant melanoma, malignant cells also invade upwards into the epidermis (blue arrow), a feature known as pagetoid spread. Note the prominent pigmentation (mostly in macrophages here) which gives these lesions their brown colour macroscopically.
15 Invasive malignant melanoma. Black arrows: junctional nests of malignant melanocytes. Blue arrows: malignant melanocytes invading upwards into the epidermis Red star: malignant melanocytes invading the dermis
16 In the absence of metastases, the prognosis of melanoma is mainly dependent on the depth of invasion into dermis measured in mm from the overlying stratum granulosum (Breslow thickness). The grade and type are not significant in determining prognosis. (From Australian Cancer Society collection 1991)
17 Seborrhoeic keratoses may be pigmented. They often have a stuck on appearance macroscopically. Micrograph (low power): Benign epidermal proliferation. (From Australian Cancer Society collection 1991)
18 Depending on their likely nature and location, skin lesions may be removed in their entirety and sent to a pathology laboratory for assessment. Such excision biopsies are therapeutic as well as diagnostic. (From Australian Cancer Society collection 1991)
19 The specimen is placed in a container of formalin, labelled, and along with a request form, sent to a pathology laboratory.
20 In the pathology laboratory, the specimen with the lesion is transversely sectioned (black lines). The slices of tissue are embedded in paraffin, sectioned and stained and the resulting histopathology section demonstrates the excision margins as well as the lesion (inset). A diagnosis is made and the referring doctor can also be informed as to whether the lesion is completely excised. (From Australian Cancer Society collection 1991)
21 Psoriasis. Thickened (acanthotic) epidermis with elongated narrow rete pegs Black arrow: absence of stratum granulosum Red star: parakeratosis Blue star: Nuclear debris and inflammatory cells: microabscess
22 Acute eczematous dermatitis. Histologically, intercellular edema produces widened intercellular spaces within the epidermis (spongiosis), eventually resulting in small, fluid-filled intraepidermal vesicles. (From Robbins & Cotran Pathologic Basis of Disease 7E Copyright Elsevier).
23 Skin: full thickness burn (low power). Burned tissue undergoes coagulative necrosis - the architecture is still discernable (e.g. black stars indicate sweat glands in deep dermis) but no nuclei are seen.
24 Skin: partial thickness burn (low power). Cells in the deep dermis are still viable (nuclei are retained) but tissue in the superficial and mid dermis shows coagulative necrosis. The epidermis is no longer present. Black arrow: inflammatory cells Blue stars: necrotic sweat glands in mid dermis Black stars: viable sweat glands in deep dermis
25 Skin, burn: sweat glands (black star) and hair follicle (red star) showing coagulative necrosis. The architecture is still discernable but no nuclei are seen. The nuclei (black arrows) in the interstitial tissues are of inflammatory cells (probably neutrophils).
26 Skin, recent wound extending into subcutaneous adipose tissue. Blood clot fills the wound (blue star). Yellow star: surface scab Black star: adjacent dermis. Such a wound with closely opposed edges, especially if sutured, will undergo healing by primary intention.
27 Skin, recently healed wound extending into subcutaneous adipose tissue (very low power). Yellow star: epidermis has regenerated across the wound. Blue star: recently formed scar. Black star: adjacent dermis.
28 Skin, early fibrous scar (S) with normal dermis (D) on either side, low power. This represents the end result of healing by primary intention as healing followed a simple incision for removal of a skin lesion. The scar here still contains quite a few fibroblasts. (From Wheater s Basic Histopathology, a Colour Atlas and Text, 4th ed. by Stevens, Lowe and Young, Churchill Livingstone.)
29 Tissue taken from an ulcer of the skin showing granulation tissue. This larger area of damage will heal by secondary intention. Healing by secondary intention also occurs in chronic peptic ulcers and following infarction in organs (except in the brain)
30 In certain situations wound healing can be complicated by excessive formation of the components of repair. In keloids, thick bundles of collagen (black star) are formed that do not regress.
Histopathology: Cervical HPV and neoplasia
Histopathology: Cervical HPV and neoplasia These presentations are to help you identify basic histopathological features. They do not contain the additional factual information that you need to learn about
More informationPathology of the skin. 2nd Department of Pathology, Semmelweis University
Pathology of the skin 2nd Department of Pathology, Semmelweis University Histology of the skin Epidermis: Stratum corneum Stratum granulosum Stratum spinosum Stratum basale Dermis: papillary and reticular
More informationBenign and malignant epithelial lesions: Seborrheic keratosis: A common benign pigmented epidermal tumor occur in middle-aged or older persons more
Benign and malignant epithelial lesions: Seborrheic keratosis: A common benign pigmented epidermal tumor occur in middle-aged or older persons more common on the trunk; but extremities, head and neck are
More informationHistopathology: healing
Histopathology: healing These presentations are to help you identify, and to test yourself on identifying, basic histopathological features. They do not contain the additional factual information that
More informationHistopathology of Melanoma
THE YALE JOURNAL OF BIOLOGY AND MEDICINE 48, 409-416 (1975) Histopathology of Melanoma G. J. WALKER SMITH Department ofpathology, Yale University School ofmedicine, 333 Cedar Street, New Haven, Connecticut
More informationActinic keratosis (AK): Dr Sarma s simple guide
Actinic keratosis (AK): Dr Sarma s simple guide Actinic keratosis is a very common lesion that you will see in your day-to-day practice. First, let me explain the name Actinic keratosis. It means keratosis
More informationMalignant tumors of melanocytes: Part 1. Deba P Sarma, MD., Omaha
Malignant tumors of melanocytes: Part 1 Deba P Sarma, MD., Omaha The melanocytic tumor is one of the most difficult and confusing areas in Dematopathology. It is true that most (95%) of such lesions are
More informationHistopathology: Cell necrosis and cytoplasmic accumulations
Histopathology: Cell necrosis and cytoplasmic accumulations These presentations are to help you identify basic histopathological features. They do not contain the additional factual information that you
More informationMECHANISMS OF HUMAN DISEASE: LABORATORY SESSION PATHOLOGY OF THE SKIN LAB. Friday, February 12, :30 am 11:00 am
MECHANISMS OF HUMAN DISEASE: LABORATORY SESSION PATHOLOGY OF THE SKIN LAB Friday, February 12, 2012 9:30 am 11:00 am FACULTY COPY GOALS: Describe the basic clinical and morphologic features of various
More informationPrinciples of Anatomy and Physiology
Principles of Anatomy and Physiology 14 th Edition CHAPTER 5 The Integumentary System Introduction The organs of the integumentary system include the skin and its accessory structures including hair, nails,
More informationB. Incorrect! The ectoderm does not produce the dermis. C. Incorrect! The dermis is derived from the mesoderm.
Human Anatomy - Problem Drill 04: The Integumentary System Question No. 1 of 10 Instructions: (1) Read the problem and answer choices carefully, (2) Work the problems on paper as 1. From the inner cell
More informationHistopathology: gastritis and peptic ulceration
Histopathology: gastritis and peptic ulceration These presentations are to help you identify, and to test yourself on identifying, basic histopathological features. They do not contain the additional factual
More informationDermatopathology: The tumor is composed of keratinocytes which show atypia, increase mitoses and abnormal mitoses.
Squamous cell carcinoma (SCC): A common malignant tumor of keratinocytes arising in the epidermis, usually from a precancerous condition: 1- UV induced actinic keratosis, usually of low grade malignancy.
More informationBasal cell carcinoma 5/28/2011
Goal of this Presentation A practical approach to the diagnosis of cutaneous carcinomas and their mimics Thaddeus Mully, MD University of California San Francisco To review common non-melanoma skin cancers
More information1. Introduction (Open your text to the image of a cross section of skin) i. Organ of the Integument. Connective Tissues. Epithelial Tissues
Integumentary System 1. Introduction (Open your text to the image of a cross section of skin) A. Integumentary System i. Organ of the Integument a. Tissues Connective Tissues * Tissue / Location Relationships
More informationAnatomy and Physiology I Student Outline The Integumentary System. Integumentary System. Page 1
Anatomy and Physiology I Student Outline The Integumentary System Integumentary System Page 1 Have a very clear understanding of the each particular tissue and their unique functions in each layer of the
More informationHistopathology: granulomatous inflammation, including tuberculosis
Histopathology: granulomatous inflammation, including tuberculosis These presentations are to help you identify basic histopathological features. They do not contain the additional factual information
More informationHistopathology: chronic inflammation
Histopathology: chronic inflammation These presentations are to help you identify, and to test yourself on identifying, basic histopathological features. They do not contain the additional factual information
More informationThis section covers the basic knowledge of normal skin structure and function required to help understand how skin diseases occur.
Background Knowledge Functions of normal skin Background Knowledge This section covers the basic knowledge of normal skin structure and function required to help understand how skin diseases occur. Learning
More informationObservations on the Pathology of Lesions Associated with Stephanofilaria dinniki Round, 1964 from the Black Rhinoceros (Diceros bicornis)
Journal of Helminthology, ~ol. XXXVIII, Nos. 1/2, 1964, pp. 171-174. Observations on the Pathology of Lesions Associated with Stephanofilaria dinniki Round, 1964 from the Black Rhinoceros (Diceros bicornis)
More informationDesmoplastic Melanoma R/O BCC. Clinical Information. 74 y.o. man with lesion on left side of neck r/o BCC
R/O BCC Sabine Kohler, M.D. Professor of Pathology and Dermatology Dermatopathology Service Stanford University School of Medicine Clinical Information 74 y.o. man with lesion on left side of neck r/o
More informationMECHANISMS OF HUMAN DISEASE: LABORATORY SESSION PATHOLOGY OF THE SKIN LAB. Friday, February 13, :30 am 11:00 am
MECHANISMS OF HUMAN DISEASE: LABORATORY SESSION PATHOLOGY OF THE SKIN LAB Friday, February 13, 2009 9:30 am 11:00 am FACULTY COPY GOALS: Describe the basic clinical and morphologic features of various
More informationCommon Benign Lesions and Skin Cancers. 22nd May 2015 Dr Mark Foley
Common Benign Lesions and Skin Cancers 22nd May 2015 Dr Mark Foley Thank you for downloading this file. This intended to supplement the presentation given at the NZ Wound Care Conference, it is not intended
More informationnumber Done by Corrected by Doctor Maha Shomaf
number 16 Done by Waseem Abo-Obeida Corrected by Zeina Assaf Doctor Maha Shomaf MALIGNANT NEOPLASMS The four fundamental features by which benign and malignant tumors can be distinguished are: 1- differentiation
More informationSkin (Integumentary System) Wheater, Chap. 9
Skin (Integumentary System) Wheater, Chap. 9 Skin (Integument) Consists of skin and associated derivatives Largest organ of body (21 ft 2 ; 9 lbs.; has 11 miles of blood vessels) Functions: Protection
More informationIntroduction. Skin and Body Membranes. Cutaneous Membranes Skin 9/14/2017. Classification of Body Membranes. Classification of Body Membranes
Introduction Skin and Body Membranes Body membranes Cover surfaces Line body cavities Form protective and lubricating sheets around organs Classified in 5 categories Epithelial membranes 3 types- cutaneous,
More informationSESSION 1: GENERAL (BASIC) PATHOLOGY CONCEPTS Thursday, October 16, :30am - 11:30am FACULTY COPY
SESSION 1: GENERAL (BASIC) PATHOLOGY CONCEPTS Thursday, October 16, 2008 9:30am - 11:30am FACULTY COPY GOAL: Describe the basic morphologic (structural) changes which occur in various pathologic conditions.
More informationSkin and Body Membranes Body Membranes Function of body membranes Cover body surfaces Line body cavities Form protective sheets around organs
Skin and Body Membranes Body Membranes Function of body membranes Cover body surfaces Line body cavities Form protective sheets around organs Classification of Body Membranes Epithelial membranes Cutaneous
More informationAnatomy Ch 6: Integumentary System
Anatomy Ch 6: Integumentary System Introduction: A. Organs are body structures composed of two or more different tissues. B. The skin and its accessory organs make up the integumentary system. Types of
More informationEXPERIMENTAL THERMAL BURNS I. A study of the immediate and delayed histopathological changes of the skin.
EXPERIMENTAL THERMAL BURNS I A study of the immediate and delayed histopathological changes of the skin. RJ Brennan, M.D. and B. Rovatti M.D. The purpose of this study was to determine the progressive
More informationDescribe the functions of the vertebrate integumentary system. Discuss the structure of the skin and how it relates to function.
Chapter 5 Describe the functions of the vertebrate integumentary system. Discuss the structure of the skin and how it relates to function. Explain the basis for different skin colors. Describe the structure
More informationPowerPoint Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College Skin and Body Membranes
PowerPoint Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College Skin and Body Membranes 4 Body Membranes Function of body membranes Cover body surfaces Line body cavities
More informationHole s Essentials of Human Anatomy & Physiology
Hole s Essentials of Human Anatomy & Physiology David Shier Jackie Butler Ricki Lewis Created by Dr. Melissa Eisenhauer Head Athletic Trainer/Assistant Professor Trevecca Nazarene University Chapter 6
More information4 Skin and Body Membranes Study Guide
Name: SKIN AND BODY MEMBRANES: 4 Skin and Body Membranes Study Guide Period: Body membranes, which cover body surfaces, line its cavities, and form protective sheets around organs, fall into two major
More informationUnit 4 - The Skin and Body Membranes 1
Unit 4 - The Skin and Body Membranes 1 I. Unit 4: Skin and Body Membranes A. Body Membranes 1. Function of body membranes a) Cover body surfaces b) Line body cavities c) Form protective sheets around organs
More informationSKIN HISTOLOGY the microscopic anatomy of the Integument. Mikrogeo. com
SKIN HISTOLOGY the microscopic anatomy of the Integument Mikrogeo. com Hair follicles, sweat glands, sebaceous glands (even teeth) are products of the epidermis,embryologically speaking ectododerm, that
More informationChapter 6 Skin and the Integumentary System. Skin Cells. Layers of Skin. Epidermis Dermis Subcutaneous layer beneath dermis not part of skin
Chapter 6 Skin and the Integumentary System Composed of several tissues Maintains homeostasis Protective covering Retards water loss Regulates body temperature Houses sensory receptors Contains immune
More informationMalignant tumors of melanocytes : Part 3. Deba P Sarma, MD., Omaha
Malignant tumors of melanocytes : Part 3 Deba P Sarma, MD., Omaha Let s go over one case of melanoma using the following worksheet. Of the various essential information that needs to be included in the
More informationCh. 4: Skin and Body Membranes
Ch. 4: Skin and Body Membranes I. Body Membranes A. Function of body membranes 1. Cover body surfaces 2. Line body cavities 3. Form protective sheets around organs II. Classification of Body Membranes
More informationHuman Anatomy & Physiology
PowerPoint Lecture Slides prepared by Barbara Heard, Atlantic Cape Community College Ninth Edition Human Anatomy & Physiology C H A P T E R 5 Annie Leibovitz/Contact Press Images 2013 Pearson Education,
More informationIntegumentary System-Skin and Body Coverings
Integumentary System-Skin and Body Coverings List the four types of epithelial or connective membranes. The epithelial cutaneous includes your and is exposed to the. Its function is to. An example is..
More informationNeoplasia 2018 Lecture 2. Dr Heyam Awad MD, FRCPath
Neoplasia 2018 Lecture 2 Dr Heyam Awad MD, FRCPath ILOS 1. List the differences between benign and malignant tumors. 2. Recognize the histological features of malignancy. 3. Define dysplasia and understand
More informationINTEGUMENTARY SYSTEM PART I: FUNCTIONS & EPIDERMIS
INTEGUMENTARY SYSTEM PART I: FUNCTIONS & EPIDERMIS Integumentary System Cutaneous membrane Epidermis (5-layers) made up of epithelial tissue only Dermis (2-layers) contains connective tissue, vessels,
More informationHistopathology: Vascular pathology
Histopathology: Vascular pathology These presentations are to help you identify basic histopathological features. They do not contain the additional factual information that you need to learn about these
More information2/5/2019. Organ System: Skin or Integumentary System. Hypodermis (or superficial fascia) Integumentary System - Learn and Understand
Integumentary System - Learn and Understand Skin is an organ comprised of all four tissues Each layer of the skin contributes to one or more of its numerous functions Skin is both strong and flexible Keratinization
More information****************************************************************************************************** INTEGUMENTARY SYSTEM
BIOLOGY 211: HUMAN ANATOMY & PHYSIOLOGY ****************************************************************************************************** INTEGUMENTARY SYSTEM ******************************************************************************************************
More informationChapter 4 Opener Pearson Education, Inc.
Chapter 4 Opener Introduction The integumentary system is composed of: Skin Hair Nails Sweat glands Oil glands Mammary glands The skin is the most visible organ of the body Clinicians can tell a lot about
More informationThe Integumentary System
The Integumentary System The Integumentary System Integument is skin Skin and its appendages make up the integumentary system (See if you can name some appendages) A fatty layer (hypodermis) lies deep
More informationCornell Notes Name: Date: Topic: CH 4
*We are revisiting Ch 3B on body tissues (Connective) prior to our study of Ch 4 Integumentary. Start on p.90 I. Connective Tissue A. Functions of Connective 1. Protection 2. Support 3. Binding Together
More informationSkin. Kristine Krafts, M.D.
Skin Kristine Krafts, M.D. Skin Lecture Objectives Describe the functions of skin. Describe the structure, location and function of the cell types found in epidermis: keratinocytes, melanocytes, Langerhans
More informationThe Integumentary System
The Integumentary System The Integumentary System Integument is skin Skin and its appendages make up the integumentary system A fatty layer (hypodermis) lies deep to it Two distinct regions Epidermis Dermis
More informationThe Integumentary System
The Integumentary System Integument is skin Skin and its appendages make up the integumentary system A fatty layer (hypodermis) lies deep to it Two distinct regions Epidermis Dermis PHL 212 1 Function
More informationDermoscopy: Recognizing Top Five Common In- Office Diagnoses
Dermoscopy: Recognizing Top Five Common In- Office Diagnoses Vu A. Ngo, DO Department of Family Medicine and Dermatology Choctaw Nation Health Services Authority Learning Objectives Introduction to dermoscopy
More informationDisorders of Cell Growth & Neoplasia. Histopathology Lab
Disorders of Cell Growth & Neoplasia Histopathology Lab Paul Hanna April 2010 Case #84 Clinical History: 5 yr-old, West Highland White terrier. skin mass from axillary region. has been present for the
More informationIntegumentary System and Body Membranes
Integumentary System and Body Membranes The Skin and its appendages hair, nails, and skin glands Anatomy/Physiology NHS http://www.lab.anhb.uwa.edu.au/mb140/corepages/integumentary/integum.htm I. System
More informationType IV collagen and laminin staining patterns in benign
J Clin Pathol 1989;42:1173-1177 Type IV collagen and laminin staining patterns in benign and malignant cutaneous lesions RONA M MacKIE, D B CLELLAND, CHRISTINE J SKERROW From the Department ofdermatology,
More informationBI 121 LAB. WEEK 2: Tissues (continued); Integumentary System
BI 121 LAB 2-1 WEEK 2: Tissues (continued); Integumentary System This week you will 1) Review the four major tissue types 2) Review the characteristics of epithelial tissues. 3) Learn the major characteristics
More informationأملس عضلي غرن = Leiomyosarcoma. Leiomyosarcoma 1 / 5
Leiomyosarcoma 1 / 5 EPIDEMIOLOGY Exact incidence is unknown, but older studies suggest that leiomyosarcomas comprise approximately 3 percent of soft-tissue sarcomas. Superficial leiomyosarcoma occurs
More informationSkin and Body Membranes
4 Skin and Body Membranes PowerPoint Lecture Slide Presentation by Jerry L. Cook, Sam Houston University ESSENTIALS OF HUMAN ANATOMY & PHYSIOLOGY EIGHTH EDITION ELAINE N. MARIEB Skin and Body Membranes
More informationINTEGUMENTARY 1-Epidermis, 2-Dermis, Structure of thick and thin skin I- Epidermis . Stratum basale
INTEGUMENTARY The skin (integument, cutis ) and its derivatives constitute the integumentary system. It form the external covering of the body and is the largest organ of the body. The skin consists of
More informationHistopathology: pulmonary pathology
Histopathology: pulmonary pathology These presentations are to help you identify basic histopathological features. They do not contain the additional factual information that you need to learn about these
More informationEx. 7: Integumentary
Collin County Community College BIOL. 2401 Ex. 7: Integumentary. Skin or Integument Consists of three major regions Epidermis outermost superficial region Dermis middle region Hypodermis (superficial fascia)
More informationSkin Cut Up D R R O K I A H A L I C O N S U L T A N T D E R M A T O P A T H O L O G I S T S T H
Skin Cut Up D R R O K I A H A L I C O N S U L T A N T D E R M A T O P A T H O L O G I S T S T H General Instructions 5.1.1 The type of biopsy is documented. 5.1.2 Orientated or not (suture indicating what
More informationLARYNGEAL DYSPLASIA. Tomas Fernandez M; 3 rd year ENT resident, Son Espases University Hospital
LARYNGEAL DYSPLASIA Tomas Fernandez M; 3 rd year ENT resident, Son Espases University Hospital INTRODUCTION Laryngeal cancer constitutes 1-2% of all malignancies diagnosed worldwide Survival is related
More informationIntegumentary System. Packet #12
Integumentary System Packet #12 Introduction Skin/Integument Skin, considered an organ, is the major component of the integumentary system. The integumentary system is also composed of other accessory
More informationThe Integementary System. The Skin & Its Parts
The Integementary System The Skin & Its Parts General Structure 2. Accessory structures: hair, nails, exocrine glands 1. Cutaneous membrane: various layers Major Functions 1. Protection 2. Temperature
More informationالمركب النموذج--- سبيتز وحمة = Type Spitz's Nevus, Compound SPITZ NEVUS 1 / 7
SPITZ NEVUS 1 / 7 Epidemiology An annual incidence rate of 1.4 cases of Spitz nevus per 100,000 individuals has been estimated in Australia, compared with 25.4 per 100,000 individuals for cutaneous melanoma
More informationWhat are the functions of the integumentary system? What are some disorders of the integumentary system?
Essential Questions: What are the functions of the integumentary system? What are some disorders of the integumentary system? How are integumentary system disorders treated? How do you relate the integumentary
More informationExternal Neoplasms in Goats: A Clinicopathological Study on Five Types. Abu-Seida, A.M and Kawkab, A. Ahmed
External Neoplasms in Goats: A Clinicopathological Study on Five Types By Abu-Seida, A.M and Kawkab, A. Ahmed Introduction Introduction Neoplasia is occasionally diagnosed in goats. A survey of 800000
More informationSKIN. 3. How is the skin structured around the finger joints to allow for flexible movement of the fingers?
SKIN Objectives for Exam #1: 1. List various skin structures and describe their functions. 2. Describe skin responses to increases and decreases in body temperature. 3. Provide examples of various skin
More informationLab 7: Integumentary System Hamilton ANSWERS TO PRE- LAB ASSIGNMENTS
Lab 7: Integumentary System Hamilton ANSWERS TO PRE- LAB ASSIGNMENTS Pre-Lab Activity 1: 1. a. epidermis b. dermis c. hypodermis d. adipose tissue e. hair f. sebaceous gland g. sweat gland 2. a Pre-Lab
More information22/04/2015. Dermoscopy of Melanoma. Ilsphi Browne. Overview
Dermoscopy of Melanoma Ilsphi Browne Overview The device Dermoscopic criteria (terminology) Colour Patterns Global features Local features Approach to diagnosing pigmented lesions Other uses in general
More informationChapter 6: Skin and the Integumentary System
Shier, Butler, and Lewis: Hole s Human Anatomy and Physiology, 10 th ed. Chapter 6: Skin and the Integumentary System Chapter 6: Skin and the Integumentary System I. Skin and Its Tissues A. Introduction
More informationBasics in Dermoscopy
Basics in Dermoscopy Manal Bosseila Professor of Dermatology, Cairo University Member of European Academy Dermatology & Venereology EADV Member of International Dermoscopy Society IDS Member of Aesthetic
More informationTHE INTEGUMENTARY SYSTEM. Body Membranes & Skin
THE INTEGUMENTARY SYSTEM Body Membranes & Skin TYPES OF MEMBRANES Epithelial Membranes includes layer of epithelial cells and connective tissue Serous Cutaneous Mucous Connective Tissue Membranes solely
More informationChapter 6 Squamous Cell Carcinoma: Variants and Challenges
Chapter 6 Squamous Cell Carcinoma: Variants and Challenges Michael B. Morgan EPIDEMIOLOGY: Second most common skin cancer, rare in the dark-skinned races. ETIOLOGY: Ultraviolet light, HPV infection. PATHOGENESIS:
More informationHistopathology: Hypertension and diabetes in the kidney These presentations are to help you identify basic histopathological features.
Histopathology: Hypertension and diabetes in the kidney These presentations are to help you identify basic histopathological features. They do not contain the additional factual information that you need
More informationChapter 6: Integumentary System
Shier, Butler, and Lewis: Hole s Human Anatomy and Physiology, 12 th ed. Chapter 6: Skin and the Integumentary System Chapter 6: Integumentary System I. Introduction 1. The skin is composed of of tissues.
More informationPrepared By Jocelyn Palao and Layla Faqih
Prepared By Jocelyn Palao and Layla Faqih The structure of the suspected atypical cell should always be compared to the structure of other similar, benign, cells which are present in the smears. The diagnosis
More informationPathology. Skin Tumor. Bayan N. Mohammad 15/10/2015. Mohammad al-orjani. Page 0 of 23
#7 35 Pathology Skin Tumor Bayan N. Mohammad 15/10/2015 Mohammad al-orjani Page 0 of 23 بسم هللا الرحمن الرحيم GREETINGS This lecture is about skin tumors, all the slides are included and every slide will
More informationThe Integumentary System: An Overview
The Integumentary System: An Overview Functions: Protective covering Helps regulate body temperature Retards water loss from deeper tissues Houses sensory receptors Synthesizes biochemicals Excretes small
More informationBenign versus Cancerous Lesions How to tell the difference FMF 2014 Christie Freeman MD, CCFP, DipPDerm, MSc
1 Benign versus Cancerous Lesions How to tell the difference FMF 2014 Christie Freeman MD, CCFP, DipPDerm, MSc Benign lesions Seborrheic Keratoses: Warty, stuck-on Genetics and birthdays Can start in late
More informationDEBRIDEMENT: ANATOMY and PHYSIOLOGY. Professor Donald G. MacLellan Executive Director Health Education & Management Innovations
DEBRIDEMENT: ANATOMY and PHYSIOLOGY Professor Donald G. MacLellan Executive Director Health Education & Management Innovations ANATOMY and PHYSIOLOGY Epidermal Layers ECM Structure Dermis Structure Skin
More informationThe Integumentary System
PowerPoint Lecture Slides prepared by Meg Flemming Austin Community College C H A P T E R 5 The Integumentary System Chapter 5 Learning Outcomes 5-1 5-2 5-3 5-4 5-5 Describe the main structural features
More informationDue next week in lab - Scientific America Article Select one article to read and complete article summary
Due in Lab 1. Skeletal System 33-34 2. Skeletal System 26 3. PreLab 6 Due next week in lab - Scientific America Article Select one article to read and complete article summary Cell Defenses and the Sunshine
More informationHole s Human Anatomy and Physiology. Eleventh Edition. Chapter 6
Hole s Human Anatomy and Physiology Eleventh Edition Shier Butler Lewis Chapter 6 Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 1 Referred to as Cutaneous Membrane
More informationIntegumentary System. Integumentary System
1. General aspects a. The integumentary system consists of several organs major organ of the system is the skin other organs are relatively small and they can be considered as specialized structures of
More informationPapillary Lesions of the breast
Papillary Lesions of the breast Emad Rakha Professor of Breast Pathology The University of Nottingham Papillary lesions of the breast are a heterogeneous group of disease, which are characterised by neoplastic
More informationEpidermis. Integumentary system
Epidermis the doctor mentioned at the begging of the lecture that the slides is from different sources and has information and details that is enough for us so we don t have to go back and read from the
More information11/8/2012. Chapter 6 Part 1 Objectives: Skin = Integument = Cutaneous Membrane. The Structure of Skin. Epidermis
Chapter 6 Part 1 Objectives: Define organ, and associate the skin as an organ of the integumentary system. List the general functions of the skin. Describe the structure of the layers of the skin. Summarize
More informationISPUB.COM. Seborrheic Keratosis: A Pictorial Review of the Histopathologic Variations. D Sarma, S Repertinger
ISPUB.COM The Internet Journal of Dermatology Volume 7 Number 2 Seborrheic Keratosis: A Pictorial Review of the Histopathologic Variations D Sarma, S Repertinger Citation D Sarma, S Repertinger.. The Internet
More informationMalignant Peripheral Nerve Sheath Tumor
C H A P T E R 120 Malignant Peripheral Nerve Sheath Tumor Currently, malignant peripheral nerve sheath tumor (MPNST) is the most commonly used generic name for the neoplasms known in the past as neurosarcoma,
More informationAssisting diagnosis of melanoma through the noninvasive biopsy of skin lesions
Assisting diagnosis of melanoma through the noninvasive biopsy of skin lesions Symon D Oyly Cotton Ela Claridge School of Computer Science, The University of Birmingham Birmingham B15 2TT, UK Per Hall
More informationSkin and Body Membranes
Essentials of Human Anatomy & Physiology Elaine N. Marieb Seventh Edition Chapter 4 Skin and Body Membranes Slides 4.1 4.32 Lecture Slides in PowerPoint by Jerry L. Cook Skin and Body Membranes Function
More informationHistopathology: Glomerulonephritis and other renal pathology
Histopathology: Glomerulonephritis and other renal pathology These presentations are to help you identify basic histopathological features. They do not contain the additional factual information that you
More informationExperiment Note the locations of the epidermis, dermis, dermal papillae, and the sweat glands. Note that fat cells that comprise the
Experiment 1 Examining Skin, Bones and Muscle Histology Experiment Inventory Skin Digital Slide Images Cortical (Compact) Bone Digital Slide Image Trabecular (Spongy) Bone Digital Slide Image Cardiac Muscle
More informationDiseases of the breast (1 of 2)
Diseases of the breast (1 of 2) Introduction A histology introduction Normal ducts and lobules of the breast are lined by two layers of cells a layer of luminal cells overlying a second layer of myoepithelial
More informationIntegumentary System
Integumentary System Overview Functions 1. Protection 2. Excretion of wastes 3. Maintenance of T b 4. Synthesis of vitamin D 3 5. Storage of lipids 6. Detection of sensory stimuli Epidermis Tissue types
More informationinsight Exceptional SKINTELL in-depth, non-invasive dermatological solution HealthCare
Optical Coherence Tomography insight Exceptional SKINTELL in-depth, non-invasive dermatological solution HealthCare From outside, exceptional insight inside SKINTELL from Agfa HealthCare enables you to
More information