Amylin Pharmaceuticals: Creating Value as a Leader in the Treatment of Diabetes

Size: px
Start display at page:

Download "Amylin Pharmaceuticals: Creating Value as a Leader in the Treatment of Diabetes"

Transcription

1 Amylin Pharmaceuticals: Creating Value as a Leader in the Treatment of Diabetes Daniel M. Bradbury President & Chief Executive Officer JPMorgan Healthcare Conference January 12, 2009 Safe Harbor Statement This presentation contains forward-looking statements about Amylin. Our actual results could differ materially from those discussed due to a number of factors, including: BYETTA and/or SYMLIN may be affected by competition, safety or other issues; clinical trials not being completed in a timely manner or achieving the intended clinical endpoints; NDAs or sndas not being submitted in a timely manner or receiving regulatory approval; expense reductions not being as large as we expect; our label update not being finalized in a timely manner; or manufacturing and supply issues. The pace of market acceptance and rate of patient adherence may also affect the potential for BYETTA and/or SYMLIN. These and other risks and uncertainties are described more fully in Amylin s most recently filed Form 10-Q. Amylin disclaims any obligation to update these forward-looking statements. 2

2 Value Creation in 2009 BYETTA Gain monotherapy approval Finalize label updates Return the product to growth EXENATIDE ONCE WEEKLY Position for launch Submit NDA Execute clinical strategy SYMLIN Continue growth OBESITY Complete Phase 2 studies Finalize development and funding strategy OPERATING RESULTS Reduce expenses and improve operating results Achieve positive cash flow by the end of Risk-Advantaged Value Creation Strategy DISEASES ASSETS GOAL RESULTS Diabetes Obesity Peptide and Protein Mimics of Human Hormones First-in-class Medicines Improve Patient and Health Outcomes Increased Shareholder Value 4

3 WITH A NEW DIAGNOSIS EVERY 21 SECONDS, DIABETES IS THE FASTEST GROWING DISEASE IN AMERICA AND THE FIFTH DEADLIEST. American Diabetes Association 5 Weight Control Linked to Growing Diabetes, Obesity, and Heart Disease Epidemics >80% of people with type 2 diabetes are overweight Obesity increases the risk of CV disease 44% in people with type 2 diabetes Cardiovascular death accounts for at least 75% of all deaths among people with diabetes Type 2 Diabetes Obese/ Overweight CV Disease Sources: Centers for Disease Control and Prevention (CDC); American Diabetes Association (ADA), Swedish National Diabetes Register (6 year follow up; ~65,000 patients-years; ~1,900 events) 6

4 Weight Control Linked to Growing Diabetes, Obesity, and Heart Disease Epidemics >80% of people with type 2 diabetes are overweight Obesity increases the risk of CV disease 44% in people with type 2 diabetes Cardiovascular death accounts for at least 75% of all deaths among people with diabetes Increase in Risk vs. Normal Weight In Type 2 Diabetes Patients Event CHD CVD Death Overweight +27% +24% +16% Obese +49% +44% +71% Sources: Centers for Disease Control and Prevention (CDC); American Diabetes Association (ADA), Swedish National Diabetes Register (6 year follow up; ~65,000 patients-years; ~1,900 events) 7 The Market is Shifting Treatments Beyond Glucose Control are Increasingly Valued LANDMARK TRIALS EXPERT ENDORSEMENT INCREASED RECOGNITION OF UNMET NEEDS TREATMENTS BEYOND GLUCOSE CONTROL UKPDS 10-Year Follow-up ACCORD ADVANCE ADA/EASD Consensus Algorithm ADA 2008 Banting Lecture Glycemic control Weight control Hypoglycemia Adherence VADT 7

5 $700 $600 $500 $400 $300 $200 $100 $ LTM Net Sales ($MM) LTM = Last Twelve Months ended 3Q08 BYETTA: Powerful Glycemic Control with Weight Loss First and only FDA-approved GLP-1 agonist Rxs declined following FDA safety posting and stabilized at end of 4Q08 Monotherapy indication and updated labeling anticipated in 1Q09 ~4 years on the market >1MM patients and large safety database Collaboration with Eli Lilly 9 BYETTA: Poised for Renewed Growth SUSTAINABILITY INNOVATION First and only daily GLP-1 Powerful glycemic control with weight loss Lower hypoglycemia risk Improved CV risk factors Established safety profile MOMENTUM Gain monotherapy approval Leverage ADA/EASD guidelines Capitalize on market shifts Enhance field force execution Patient and HCP education and support Reinforce broad managed care access BYETTA is the only daily GLP-1 agonist currently available 10

6 The Inconvenient Truth: Not all GLP-1 Agonists are Created Equal METABOLISM Exenatide is a natural molecule with no chemical modification Exenatide metabolism is known, has no metabolic byproduct cleared intact through the kidney EXPERIENCE Only exenatide has been on the market nearly 4 years >1MM patients ~85% tier 2 managed care access 11 The Inconvenient Truth: Not all GLP-1 Agonists are Created Equal BYETTA is the first and only GLP-1 available, and sets the bar for daily GLP-1s 12

7 WHEN THE ONCE-A-WEEK EXENATIDE FORMULATION BECOMES AVAILABLE THIS NEW STRATEGY MIGHT SUBSTANTIALLY CHANGE THE MANAGEMENT OF TYPE 2 DIABETES. Scheen AJ. Lancet 2008;372: Exenatide Once Weekly: Opportunity to Transform Diabetes Therapy Provides continuous therapeutic levels of exenatide, in a once-weekly dose, resulting in: 2% A1C reduction 9.5-lb Weight loss Powerful A1C reductions 74% of patients achieving endpoint A1C 7% Weight loss Improved CV risk factors No increased risk of hypoglycemia when used with metformin or a TZD Improved tolerability profile 14

8 Exenatide Once Weekly NDA Submission Pathway Established FDA feedback: DURATION-1 sufficient for NDA DURATION-1 extension appropriate to demonstrate manufacturing comparability results in 1Q09 Meta-analysis on entire exenatide safety database to evaluate CV risk NDA submission by end of 1H09 15 Positioning Exenatide Once Weekly for Market Dominance Comparator Design Background Subjects Results DURATION-2 Sitagliptin or pioglitazone Double blind, Metformin Q09 DURATION-3 Insulin glargine Open label, Metformin +/- SFU Q09 DURATION-4 Metformin, sitagliptin or pioglitazone Double blind, Drug naïve CV Outcomes Standard of care Double blind, Drug naïve mono and combo failures 12,000+ Interim: 2012 Final:

9 Positioning Exenatide Once Weekly for Market Dominance Comparator Design Background Subjects Results DURATION-2 Sitagliptin or pioglitazone Double blind, Metformin Q09 DURATION-3 Insulin glargine Open label, Metformin +/- SFU Q09 DURATION-4 Metformin, sitagliptin or pioglitazone Double blind, Drug naïve CV Outcomes Standard of care Double blind, Drug naïve mono and combo failures 12,000+ Interim: 2012 Final: Exenatide Once Weekly: Transforming Diabetes Therapy First once weekly diabetes therapy ever Transformational efficacy supported by BYETTA safety profile FDA path established for regulatory submission Manufacturing facility operational ready to go Clinical plan for market dominance Unique value proposition to patients, physicians and payors 18

10 $90 $80 $70 $60 $50 $40 $30 $20 $10 $ LTM Net Sales ($MM) SYMLIN: Steady Growth Addresses key unmet needs of insulin therapy Glucose fluctuations reduced Glucose control improved Weight loss Amylin owns 100% of economics ~4 years on the market Used by >100,000 patients with type 1 or type 2 diabetes LTM = Last Twelve Months ended 3Q08 19 SYMLIN: Enables Patients to Fine Tune their Glucose and Weight Control MOMENTUM FOCUS Targeted physicians Patient selection Patient expectations INNOVATION SymlinPen launched January 2008 Innovation = convenience Continued patient support and physician education Improved persistence A Pen and a Partner The SYMLIN Support Program SM 20

11 OBESE PEOPLE DESERVE ACCESS TO SAFE AND EFFECTIVE MEDICATIONS PHYSICIANS ARE EAGER TO HAVE ADDITIONAL TOOLS TO HELP THEIR PATIENTS. Caroline Apovian, The Obesity Society 21 Opportunity to Transform Therapies in Obesity Amylin/Leptin analogs 12.7% weight loss over 24 weeks Phase 2B dose-ranging results 3Q09 Davalintide (AC2307), 2nd generation amylin analog Phase 2 results 4Q09 Potential for enhanced efficacy and less frequent dosing 22

12 Value Creation Opportunities in Q 2Q 3Q 4Q BYETTA Monotherapy & Label Revision DURATION-1 Extension Comparability Results DURATION-2 Results DURATION-3 Results Submit Exenatide Once Weekly NDA Initiate Exenatide Once Weekly CV Outcomes Study Pramlintide/Metreleptin Phase 2B Results Davalintide (AC2307) Phase 2 Results Finalize Obesity Development and Funding Strategy 23 Value Creation in 2009 BYETTA Gain monotherapy approval Finalize label updates Return the product to growth EXENATIDE ONCE WEEKLY Position for launch Submit NDA Execute clinical strategy SYMLIN Continue growth OBESITY Complete Phase 2 studies Finalize development and funding strategy OPERATING RESULTS Reduce expenses and improve operating results Achieve positive cash flow by the end of

Lilly Diabetes: Pipeline Update

Lilly Diabetes: Pipeline Update Lilly Diabetes: Pipeline Update June 16, 2014 Safe Harbor Provision This presentation contains forward-looking statements that are based on management's current expectations, but actual results may differ

More information

Eli Lilly and Company Investment Community Meeting

Eli Lilly and Company Investment Community Meeting Eli Lilly and Company Investment Community Meeting October 3, 2013 8:30 a.m. 12:30 p.m. Safe Harbor Provision This presentation contains forward-looking statements that are based on management's current

More information

Eli Lilly and Company

Eli Lilly and Company Eli Lilly and Company Strategic Diabetes Alliance with Boehringer Ingelheim January 11 th, 2011 Safe Harbor Provision This presentation contains forward-looking statements that are based on management's

More information

AstraZeneca to Acquire Bristol- Myers Squibb Share of Global Diabetes Alliance. Becoming Global Leaders In Diabetes

AstraZeneca to Acquire Bristol- Myers Squibb Share of Global Diabetes Alliance. Becoming Global Leaders In Diabetes AstraZeneca to Acquire Bristol- Myers Squibb Share of Global Diabetes Alliance Becoming Global Leaders In Diabetes 19th December 2013 Cautionary Statement Regarding Forward-Looking Statements In order,

More information

Diabetes Guidelines in View of Recent Clinical Trials Are They Still Applicable?

Diabetes Guidelines in View of Recent Clinical Trials Are They Still Applicable? Diabetes Guidelines in View of Recent Clinical Trials Are They Still Applicable? Jay S. Skyler, MD, MACP Division of Endocrinology, Diabetes, and Metabolism and Diabetes Research Institute University of

More information

Amylin Pharmaceuticals Inc. Research and Development Breakfast

Amylin Pharmaceuticals Inc. Research and Development Breakfast Challenging Science. Changing Lives. Amylin Pharmaceuticals Inc. Research and Development Breakfast October 24, 2006 1 Safe Harbor Statement > This presentation contains forward-looking statements about

More information

Hanyang University Guri Hospital Chang Beom Lee

Hanyang University Guri Hospital Chang Beom Lee Hanyang University Guri Hospital Chang Beom Lee Meal prayer, Van Brekelenkam 17 th C Introduction 2012 ADA/EASD Position Statement Proper Patients for Pioglitazone β-cell Preservation by Pioglitazone Benefit

More information

The Dual Hormonal Artificial Pancreas in Diabetes Management. Medical Innovation Day Challenge

The Dual Hormonal Artificial Pancreas in Diabetes Management. Medical Innovation Day Challenge The Dual Hormonal Artificial Pancreas in Diabetes Management Medical Innovation Day Challenge 1 Background for the challenge A paradigm shift in treating diabetes Zealand Pharma is a Danish biotech company

More information

A Clinical Context Report

A Clinical Context Report Type 2 Diabetes in Practice An Expert Commentary with Silvio E. Inzucchi, MD A Clinical Context Report Clinical Context: Type 2 Diabetes in Practice Expert Commentary Jointly Sponsored by: and Clinical

More information

Changing Diabetes: The time is now!

Changing Diabetes: The time is now! Midwest Cardiovascular Research Foundation Welcomes DANITA HARRISON, ARNP Ms. Harrison discloses speaking relationships with Lilly, Novo Nordisk and Pfizer. Changing Diabetes: The time is now! Danita Harrison

More information

Chief of Endocrinology East Orange General Hospital

Chief of Endocrinology East Orange General Hospital Targeting the Incretins System: Can it Improve Our Ability to Treat Type 2 Diabetes? Darshi Sunderam, MD Darshi Sunderam, MD Chief of Endocrinology East Orange General Hospital Age-adjusted Percentage

More information

Daiichi Sankyo, Inc. (DSI)

Daiichi Sankyo, Inc. (DSI) Daiichi Sankyo, Inc. (DSI) Outlook for U.S. Business for 2009 Nov. 7 th, 2007 Joseph P. Pieroni President and CEO Daiichi Sankyo, Inc. Largest Pharmaceutical markets $300 $274.4 Annual Sales (US$ billions)

More information

Media Contacts: Amy Rose Investor Contact: Graeme Bell (908) (908)

Media Contacts: Amy Rose Investor Contact: Graeme Bell (908) (908) News Release FOR IMMEDIATE RELEASE Media Contacts: Amy Rose Investor Contact: Graeme Bell (908) 423-6537 (908) 423-5185 Tracy Ogden (267) 305-0960 FDA Approves Once-Daily JANUVIA, the First and Only DPP-4

More information

N A S D A Q : E V F M

N A S D A Q : E V F M N A S D A Q : E V F M Jefferies Global Healthcare Conference June 7, 2018 Disclaimer This presentation contains forward looking statements within the meaning of The Private Securities Litigation Reform

More information

Slide 1. Investor presentation. London 5 February 2019

Slide 1. Investor presentation. London 5 February 2019 Slide Investor presentation London 5 February 209 Slide 2 Forward-looking statements Novo Nordisk s reports filed with or furnished to the US Securities and Exchange Commission (SEC), including this presentation

More information

CASE A2 Managing Between-meal Hypoglycemia

CASE A2 Managing Between-meal Hypoglycemia Managing Between-meal Hypoglycemia 1 I would like to discuss this case of a patient who, overall, was doing well on her therapy until she made an important lifestyle change to lose weight. This is a common

More information

Oral Hypoglycemics and Risk of Adverse Cardiac Events: A Summary of the Controversy

Oral Hypoglycemics and Risk of Adverse Cardiac Events: A Summary of the Controversy Oral Hypoglycemics and Risk of Adverse Cardiac Events: A Summary of the Controversy Jeffrey Boord, MD, MPH Advances in Cardiovascular Medicine Kingston, Jamaica December 7, 2012 VanderbiltHeart.com Outline

More information

FARXIGA (dapagliflozin) Jardiance (empagliflozin) tablets. Synjardy (empagliflozin and metformin hydrochloride) tablets. GLUCOPHAGE* (metformin)

FARXIGA (dapagliflozin) Jardiance (empagliflozin) tablets. Synjardy (empagliflozin and metformin hydrochloride) tablets. GLUCOPHAGE* (metformin) Type 2 Medications Drug Class How It Works Brand and Generic Names Manufacturers Usual Starting Dose The kidneys filter sugar and either absorb it back into your body for energy or remove it through your

More information

Oppenheimer 29th Annual Healthcare Conference Mark Timney, Chief Executive Officer

Oppenheimer 29th Annual Healthcare Conference Mark Timney, Chief Executive Officer Oppenheimer 29th Annual Healthcare Conference Mark Timney, Chief Executive Officer New York City 20th March 2019 1 Safe Harbor Forward-looking statements Statements contained in this presentation about

More information

Glucagon-like peptide-1 (GLP-1) Agonists Drug Class Prior Authorization Protocol

Glucagon-like peptide-1 (GLP-1) Agonists Drug Class Prior Authorization Protocol Glucagon-like peptide-1 (GLP-1) Agonists Drug Class Prior Authorization Protocol Line of Business: Medicaid P&T Approval Date: February 21, 2018 Effective Date: April 1, 2018 This policy has been developed

More information

Reviewing Diabetes Guidelines. Newsletter compiled by Danny Jaek, Pharm.D. Candidate

Reviewing Diabetes Guidelines. Newsletter compiled by Danny Jaek, Pharm.D. Candidate Reviewing Diabetes Guidelines Newsletter compiled by Danny Jaek, Pharm.D. Candidate AL AS KA N AT IV E DI AB ET ES TE A M Volume 6, Issue 1 Spring 2011 Dia bet es Dis pat ch There are nearly 24 million

More information

A Guidance Statement from the American College of Physicians

A Guidance Statement from the American College of Physicians Hemoglobin A1c Targets for Glycemic Control with Pharmacologic Therapy in Non-Pregnant Adults with Type 2 Diabetes Mellitus: A Guidance Statement from the American College of Physicians Timothy J. Wilt,

More information

Merck & Co, Inc. Announced Approval of JANUVIA TM (INN: sitagliptin), a new oral treatment of diabetes, by the US FDA

Merck & Co, Inc. Announced Approval of JANUVIA TM (INN: sitagliptin), a new oral treatment of diabetes, by the US FDA October 23, 2006 Ono Pharmaceutical Co., Ltd., Public Relations Phone: +81-6-6263-5670 Banyu Pharmaceutical Co., Ltd., Public Relations Phone: +81-3-6272-1001 Merck & Co, Inc. Announced Approval of JANUVIA

More information

Patrick J. Sullivan, President & CEO March 7, 2016 Raymond James 37 th Annual Institutional Conference

Patrick J. Sullivan, President & CEO March 7, 2016 Raymond James 37 th Annual Institutional Conference Patrick J. Sullivan, President & CEO March 7, 2016 Raymond James 37 th Annual Institutional Conference Forward Looking Statement This presentation may contain forward-looking statements concerning Insulet's

More information

Achieving and maintaining good glycemic control is an

Achieving and maintaining good glycemic control is an Glycemic Efficacy, Weight Effects, and Safety of Once-Weekly Glucagon-Like Peptide-1 Receptor Agonists Yehuda Handelsman, MD, FACP, FNLA, FASPC, MACE; Kathleen Wyne, MD, PhD, FACE, FNLA; Anthony Cannon,

More information

AVEO and Astellas Report Final Overall Survival Results from TIVO-1

AVEO and Astellas Report Final Overall Survival Results from TIVO-1 AVEO and Astellas Report Final Overall Survival Results from TIVO-1 - Median Overall Survival of 28.8 Months Reported for Tivozanib in Patients with Advanced Kidney Cancer - CAMBRIDGE, Mass. and TOKYO,

More information

exenatide 2mg powder and solvent for prolonged-release suspension for injection (Bydureon ) SMC No. (748/11) Eli Lilly and Company Limited

exenatide 2mg powder and solvent for prolonged-release suspension for injection (Bydureon ) SMC No. (748/11) Eli Lilly and Company Limited exenatide 2mg powder and solvent for prolonged-release suspension for injection (Bydureon ) SMC No. (748/11) Eli Lilly and Company Limited 09 December 2011 The Scottish Medicines Consortium (SMC) has completed

More information

AVENUE THERAPEUTICS, INC. NASDAQ: ATXI JANUARY 2018

AVENUE THERAPEUTICS, INC. NASDAQ: ATXI JANUARY 2018 AVENUE THERAPEUTICS, INC. NASDAQ: ATXI JANUARY 2018 Forward Looking Statements Statements in this presentation that are not descriptions of historical facts are forward-looking statements within the meaning

More information

A Practical Approach to the Use of Diabetes Medications

A Practical Approach to the Use of Diabetes Medications A Practical Approach to the Use of Diabetes Medications Juan Pablo Frias, M.D., FACE President, National Research Institute, Los Angles, CA Clinical Faculty, University of California, San Diego, CA OUTLINE

More information

The Many Faces of T2DM in Long-term Care Facilities

The Many Faces of T2DM in Long-term Care Facilities The Many Faces of T2DM in Long-term Care Facilities Question #1 Which of the following is a risk factor for increased hypoglycemia in older patients that may suggest the need to relax hyperglycemia treatment

More information

Practical Strategies for the Clinical Use of Incretin Mimetics CME/CE. CME/CE Released: 09/15/2009; Valid for credit through 09/15/2010

Practical Strategies for the Clinical Use of Incretin Mimetics CME/CE. CME/CE Released: 09/15/2009; Valid for credit through 09/15/2010 Practical Strategies for the Clinical Use of Incretin Mimetics CME/CE Robert R. Henry, MD Authors and Disclosures CME/CE Released: 09/15/2009; Valid for credit through 09/15/2010 Introduction Type 2 diabetes

More information

Dealdoc Collaborative R&D and marketing agreement for diabetes product portfolio

Dealdoc Collaborative R&D and marketing agreement for diabetes product portfolio Dealdoc Collaborative R&D and marketing agreement for diabetes product portfolio Bristol-Myers Squibb AstraZeneca Amylin Pharmaceuticals Jun 29 2012 Collaborative R&D and marketing agreement for diabetes

More information

Developing & Commercializing Targeted Small Molecule Drugs in Cancer

Developing & Commercializing Targeted Small Molecule Drugs in Cancer Developing & Commercializing Targeted Small Molecule Drugs in Cancer SAFE HARBOR STATEMENT 2 Forward-looking statements made in the course of this presentation are made pursuant to the safe harbor provisions

More information

Idenix Pharmaceuticals Building a Leading Antiviral Franchise. Cowen & Company 27 th Annual Healthcare Conference March 13, 2007 Boston

Idenix Pharmaceuticals Building a Leading Antiviral Franchise. Cowen & Company 27 th Annual Healthcare Conference March 13, 2007 Boston Idenix Pharmaceuticals Building a Leading Antiviral Franchise Cowen & Company 27 th Annual Healthcare Conference March 13, 2007 Boston Safe Harbor This presentation includes forward-looking statements

More information

Emisphere Technologies, Inc. Announces 2008 Second Quarter Financial Results

Emisphere Technologies, Inc. Announces 2008 Second Quarter Financial Results August 11, 2008 Emisphere Technologies, Inc. Announces 2008 Second Quarter Financial Results Conference Call/Webcast to be Held Monday, August 11 at 10:00 AM EDT CEDAR KNOLLS, N.J., Aug 11, 2008 /PRNewswire-FirstCall

More information

Oral semaglutide and production expansion. Henrik Wulff EVP Product Supply. Peter Kristensen SVP Global Development

Oral semaglutide and production expansion. Henrik Wulff EVP Product Supply. Peter Kristensen SVP Global Development YASMIN FIEDLER Germany Yasmin has type 1 diabetes Slide 1 Oral semaglutide and production expansion Henrik Wulff EVP Product Supply Peter Kristensen SVP Global Development Slide 2 Forward-looking statements

More information

Breaking the Cycle: Using Incretin-Based Therapies to Overcome Clinical Inertia in Type 2 Diabetes

Breaking the Cycle: Using Incretin-Based Therapies to Overcome Clinical Inertia in Type 2 Diabetes Breaking the Cycle: Using Incretin-Based Therapies to Overcome Clinical Inertia in Type 2 Diabetes Taking It to the Next Level: Pearls for Your Clinical Practice Thursday, April 23, 2009 6:00 AM - 8:00

More information

Horizon Scanning Technology Summary. Liraglutide for type 2 diabetes. National Horizon Scanning Centre. April 2007

Horizon Scanning Technology Summary. Liraglutide for type 2 diabetes. National Horizon Scanning Centre. April 2007 Horizon Scanning Technology Summary National Horizon Scanning Centre Liraglutide for type 2 diabetes April 2007 This technology summary is based on information available at the time of research and a limited

More information

Age-adjusted Percentage of U.S. Adults Who Were Obese or Who Had Diagnosed Diabetes

Age-adjusted Percentage of U.S. Adults Who Were Obese or Who Had Diagnosed Diabetes Age-adjusted Percentage of U.S. Adults Who Were Obese or Who Had Diagnosed Diabetes Obesity (BMI 30 kg/m 2 ) 1994 2000 2009 No Data 26.0% Diabetes 1994 2000 2009

More information

Du gusts is megl che one. Edoardo Mannucci

Du gusts is megl che one. Edoardo Mannucci Du gusts is megl che one Edoardo Mannucci Conflitti di interessi Negli ultimi due anni, E. Mannucci ha ricevuto compensi per relazioni e/o consulenze da: Abbott, AstraZeneca, Boehringer Ingelheim, Eli

More information

DIABETES - FACT SHEET

DIABETES - FACT SHEET DIABETES - FACT SHEET What is diabetes? Diabetes mellitus, often shortened to diabetes, is a chronic condition that affects the body's ability to control blood sugar level and use energy from food. In

More information

What s New on the Horizon: Diabetes Medication Update

What s New on the Horizon: Diabetes Medication Update What s New on the Horizon: Diabetes Medication Update Outline of Talk Newly released and upcoming medications: the incretins, DPP-IV inhibitors, and what s coming Revised ADA/EASD and AACE guidelines:

More information

See Important Reminder at the end of this policy for important regulatory and legal information.

See Important Reminder at the end of this policy for important regulatory and legal information. Clinical Policy: Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Reference Number: HIM.PA.53 Effective Date: 03.01.18 Last Review Date: 02.18 Line of Business: Health Insurance Marketplace See Important

More information

Cowen Investor Conference March confidently live life with ease

Cowen Investor Conference March confidently live life with ease Cowen Investor Conference March 2018 confidently live life with ease Forward-Looking Statements This presentation contains certain forward-looking statements that involve risks and uncertainties that could

More information

Slide 1. Winning with GLP-1. Lars Fruergaard Jørgensen President and CEO. ALEXANDRE DE GREGORIO, Brazil Alexandre has type 2 diabetes

Slide 1. Winning with GLP-1. Lars Fruergaard Jørgensen President and CEO. ALEXANDRE DE GREGORIO, Brazil Alexandre has type 2 diabetes Slide 1 Lars Fruergaard Jørgensen President and CEO ALEXANDRE DE GREGORIO, Brazil Alexandre has type 2 diabetes Slide 2 Forward-looking statements Novo Nordisk s reports filed with or furnished to the

More information

AVEO and Astellas Announce TAURUS Patient Preference Clinical Study Comparing Tivozanib with Sunitinib in First-Line Kidney Cancer

AVEO and Astellas Announce TAURUS Patient Preference Clinical Study Comparing Tivozanib with Sunitinib in First-Line Kidney Cancer FOR IMMEDIATE RELEASE AVEO and Astellas Announce TAURUS Patient Preference Clinical Study Comparing Tivozanib with Sunitinib in First-Line Kidney Cancer Study designed to build upon safety profile demonstrated

More information

LEERINK GLOBAL HEALTHCARE CONFERENCE. Marino Garcia EVP, Chief Strategy Officer February 15, 2017

LEERINK GLOBAL HEALTHCARE CONFERENCE. Marino Garcia EVP, Chief Strategy Officer February 15, 2017 LEERINK GLOBAL HEALTHCARE CONFERENCE Marino Garcia EVP, Chief Strategy Officer February 15, 2017 SAFE HARBOR STATEMENT This presentation and any statements made for and during any presentation or meeting

More information

Nexus BioPharma, Inc. Opportunity Overview

Nexus BioPharma, Inc. Opportunity Overview Nexus BioPharma, Inc Opportunity Overview Forward Looking Statements This presentation contains forward-looking statements within the meaning of the Securities Act of 1933, as amended, the Securities Exchange

More information

BioCryst Pharmaceuticals

BioCryst Pharmaceuticals BioCryst Pharmaceuticals Jefferies 2010 Global Life Sciences Conference New York Stuart Grant Senior Vice President & Chief Financial Officer Rob Bennett Executive Director, Investor Relations & Business

More information

Lehman Brothers Eighth Annual Global Healthcare Conference March 30, 2005 Bruce A. Peacock President and Chief Executive Officer

Lehman Brothers Eighth Annual Global Healthcare Conference March 30, 2005 Bruce A. Peacock President and Chief Executive Officer Lehman Brothers Eighth Annual Global Healthcare Conference March 30, 2005 Bruce A. Peacock President and Chief Executive Officer 2005 Adolor Corporation. All rights reserved. Safe Harbor Statement This

More information

Zealand Pharma A/S Interim report for Q (un-audited)

Zealand Pharma A/S Interim report for Q (un-audited) Company Announcement No. 12/2012 (un-audited) Net profit for the quarter of DKK 66 (EUR 9) million Important pipeline progress, and revenue from milestone payments of DKK 120 (EUR 16) million Cash and

More information

What s the Goal? Individualizing Glycemic Targets. Matthew Freeby M.D. December 3 rd, 2016

What s the Goal? Individualizing Glycemic Targets. Matthew Freeby M.D. December 3 rd, 2016 What s the Goal? Individualizing Glycemic Targets Matthew Freeby M.D. December 3 rd, 2016 Diabetes Mellitus: Complications and Co-Morbid Conditions Retinopathy Between 2005-2008, 28.5% of patients with

More information

Galvus US NDA Approvable - Overview

Galvus US NDA Approvable - Overview Galvus US NDA Approvable - Overview Galvus NDA filed with FDA Jan 2006 PDUFA action date extended by 3 months until February 26th 2007 Significant new clinical data added to NDA - Approximately 1000 patient

More information

Egalet Corporate Presentation

Egalet Corporate Presentation Egalet Corporate Presentation Specialty Pharmaceutical Company Focused on Pain 1 NASDAQ: EGLT Forward-Looking Statements Statements included in this presentation that are not historical in nature are "forward-looking

More information

This program applies to Commercial, GenPlus and Health Insurance Marketplace formularies.

This program applies to Commercial, GenPlus and Health Insurance Marketplace formularies. OBJECTIVE The intent of the GLP-1 (glucagon-like peptide-1) Agonists [Adlyxin (lixisenatide), Byetta (exenatide), Bydureon (exenatide extended-release), Tanzeum (albiglutide), Trulicity (dulaglutide),

More information

Annual Stockholder Meeting May 30, confidently live life with ease

Annual Stockholder Meeting May 30, confidently live life with ease Annual Stockholder Meeting May 30, 2018 confidently live life with ease Forward-Looking Statements This presentation contains certain forward-looking statements that involve risks and uncertainties that

More information

Insulin Initiation and Intensification. Disclosure. Objectives

Insulin Initiation and Intensification. Disclosure. Objectives Insulin Initiation and Intensification Neil Skolnik, M.D. Associate Director Family Medicine Residency Program Abington Memorial Hospital Professor of Family and Community Medicine Temple University School

More information

6/1/2018. Lou Haenel, IV, DO, FACE, FACOI Endocrinology Roper St Francis Charleston, SC THE OMINOUS OCTET: HOW PATHOPHYSIOLOGY AND THERAPY MERGE

6/1/2018. Lou Haenel, IV, DO, FACE, FACOI Endocrinology Roper St Francis Charleston, SC THE OMINOUS OCTET: HOW PATHOPHYSIOLOGY AND THERAPY MERGE Lou Haenel, IV, DO, FACE, FACOI Endocrinology Roper St Francis Charleston, SC THE OMINOUS OCTET: HOW PATHOPHYSIOLOGY AND THERAPY MERGE 1 2 3 Sulfonylureas Glipizide Glyburide Glimeperide 4 Metformin Gold

More information

AVEO and Astellas Announce Positive Findings from TIVO-1 Superiority Study of Tivozanib in First-Line Advanced RCC

AVEO and Astellas Announce Positive Findings from TIVO-1 Superiority Study of Tivozanib in First-Line Advanced RCC FOR IMMEDIATE RELEASE AVEO and Astellas Announce Positive Findings from TIVO-1 Superiority Study of Tivozanib in First-Line Advanced RCC - Tivozanib is the First Agent to Demonstrate Greater than One Year

More information

REFERENCE CODE GDHC233DFR PUBLICAT ION DATE JULY 2013 ALBIGLUTIDE (TYPE 2 DIABETES) - FORECAST AND MARKET ANALYSIS TO 2022

REFERENCE CODE GDHC233DFR PUBLICAT ION DATE JULY 2013 ALBIGLUTIDE (TYPE 2 DIABETES) - FORECAST AND MARKET ANALYSIS TO 2022 REFERENCE CODE GDHC233DFR PUBLICAT ION DATE JULY 2013 ALBIGLUTIDE (TYPE 2 DIABETES) - Executive Summary Below table provides a summary of Albiglutide for Type 2 diabetes in the 10 major pharmaceutical

More information

Results of Phase III Studies of Sitagliptin, new oral treatment of diabetes, were presented by Merck & Co., Inc. at ADA (The 2 nd Announcement)

Results of Phase III Studies of Sitagliptin, new oral treatment of diabetes, were presented by Merck & Co., Inc. at ADA (The 2 nd Announcement) June 14, 2006 Ono Pharmaceutical Co., Ltd., Public Relations Tel: +81-6-6263-5670 Banyu Pharmaceutical Co., Ltd., Public Relations Tel: +81-3-6272-1001 Results of Phase III Studies of Sitagliptin, new

More information

Jefferies Healthcare Conference

Jefferies Healthcare Conference Jefferies Healthcare Conference June 7, 2016 NASDAQ: CHMA Forward-Looking Statements These slides contain forward-looking statements and information. The use of words such as may, might, will, should,

More information

효과적인경구혈당강하제의조합은? 대한당뇨병학회제 17 차연수강좌 ( ) 가천의대길병원내분비대사내과

효과적인경구혈당강하제의조합은? 대한당뇨병학회제 17 차연수강좌 ( ) 가천의대길병원내분비대사내과 효과적인경구혈당강하제의조합은? 대한당뇨병학회제 17 차연수강좌 (2011.10.30.) 가천의대길병원내분비대사내과 박이병 내용 배경 경구혈당강하제의병합이왜필요한가? (WHY?) 경구혈당강하제의병합은언제시작하나? (WHEN?) 경구혈당강하제의병합은어떻게하는것이좋은가?(HOW) 맺음말 배경 : drugs for treating diabetes In 1995 :

More information

GLP-1 (glucagon-like peptide-1) Agonists (Byetta, Bydureon, Tanzeum, Trulicity, Victoza ) Step Therapy and Quantity Limit Criteria Program Summary

GLP-1 (glucagon-like peptide-1) Agonists (Byetta, Bydureon, Tanzeum, Trulicity, Victoza ) Step Therapy and Quantity Limit Criteria Program Summary OBJECTIVE The intent of the GLP-1 (glucagon-like peptide-1) s (Byetta/exenatide, Bydureon/ exenatide extended-release, Tanzeum/albiglutide, Trulicity/dulaglutide, and Victoza/liraglutide) Step Therapy

More information

What s New on the Horizon: Diabetes Medication Update. Michael Shannon, MD Providence Endocrinology, Olympia WA

What s New on the Horizon: Diabetes Medication Update. Michael Shannon, MD Providence Endocrinology, Olympia WA What s New on the Horizon: Diabetes Medication Update Michael Shannon, MD Providence Endocrinology, Olympia WA 1 Outline of Talk Newly released and upcoming medications: the incretins, DPP-IV inhibitors,

More information

Clinical Policy: Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Reference Number: HIM.PA.53 Effective Date: Last Review Date: 02.

Clinical Policy: Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Reference Number: HIM.PA.53 Effective Date: Last Review Date: 02. Clinical Policy: Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Reference Number: HIM.PA.53 Effective Date: 03.01.18 Last Review Date: 02.19 Line of Business: HIM Revision Log See Important Reminder

More information

No Increased Cardiovascular Risk for Lixisenatide in ELIXA

No Increased Cardiovascular Risk for Lixisenatide in ELIXA ON ISSUES IN THE MANAGEMENT OF TYPE 2 DIABETES JUNE 2015 Coverage of data from ADA 2015, June 5 9 in Boston, Massachusetts No Increased Cardiovascular Risk for Lixisenatide in ELIXA First Cardiovascular

More information

SPHERIX ANNOUNCES FIRST QUARTER 2010 FINANCIAL RESULTS

SPHERIX ANNOUNCES FIRST QUARTER 2010 FINANCIAL RESULTS SPHERIX Investor Relations Phone: (301) 897-2564 Email: info@spherix.com SPHERIX ANNOUNCES FIRST QUARTER 2010 FINANCIAL RESULTS BETHESDA, MD, May 21, 2010 - Spherix Incorporated (NASDAQ CM: SPEX), an innovator

More information

3/8/2011. Julie M. Sease, Pharm D, BCPS, CDE Associate Professor of Pharmacy Practice Presbyterian College School of Pharmacy

3/8/2011. Julie M. Sease, Pharm D, BCPS, CDE Associate Professor of Pharmacy Practice Presbyterian College School of Pharmacy Summarize revisions to the 2011 American Diabetes Association clinical practice guidelines. Evaluate bromocriptine as a therapeutic option in the management of type 2 diabetes. Compare and contrast the

More information

Ipsen Acquisition of Clementia Pharmaceuticals. February 25, 2019

Ipsen Acquisition of Clementia Pharmaceuticals. February 25, 2019 Ipsen Acquisition of Clementia Pharmaceuticals February 25, 2019 Disclaimer & Safe Harbor This presentation includes only summary information and does not purport to be comprehensive. Forward-looking statements,

More information

REPROS THERAPEUTICS. Dedicated to Treating Male and Female Reproductive Disorders. Corporate Presentation. September 2017

REPROS THERAPEUTICS. Dedicated to Treating Male and Female Reproductive Disorders. Corporate Presentation. September 2017 REPROS THERAPEUTICS Dedicated to Treating Male and Female Reproductive Disorders Corporate Presentation September 2017 Safe Harbor Any statements made by the Company that are not historical facts contained

More information

Slide 1. Financial update and closing remarks. Jesper Brandgaard EVP and CFO. RAFAEL DE JESÚS FLORES, Mexico Rafael has haemophilia A

Slide 1. Financial update and closing remarks. Jesper Brandgaard EVP and CFO. RAFAEL DE JESÚS FLORES, Mexico Rafael has haemophilia A Slide 1 Financial update and closing remarks Jesper Brandgaard EVP and CFO RAFAEL DE JESÚS FLORES, Mexico Rafael has haemophilia A Slide 2 Forward-looking statements Novo Nordisk s reports filed with or

More information

REFERENCE CODE GDHC220DFR PUBLICAT ION DATE JULY 2013 JANUVIA (TYPE 2 DIABETES) - FORECAST AND MARKET ANALYSIS TO 2022

REFERENCE CODE GDHC220DFR PUBLICAT ION DATE JULY 2013 JANUVIA (TYPE 2 DIABETES) - FORECAST AND MARKET ANALYSIS TO 2022 REFERENCE CODE GDHC220DFR PUBLICAT ION DATE JULY 2013 JANUVIA (TYPE 2 DIABETES) - Executive Summary Below table provides a summary of Januvia for Type 2 diabetes in the 10 major pharmaceutical markets

More information

AMYLIN PHARMACEUTICALS, INC. ANNUAL REPORT 2004

AMYLIN PHARMACEUTICALS, INC. ANNUAL REPORT 2004 AMYLIN PHARMACEUTICALS, INC. ANNUAL REPORT 2004 THERE S AN ENERGY THAT PERMEATES THE HALLS OF AMYLIN, and a growing sense of excitement shared by over 600 dedicated men and women whose talent and passion

More information

Halozyme Therapeutics, Inc.

Halozyme Therapeutics, Inc. Halozyme Therapeutics, Inc. The Next Chapter Begins: Creating Value Through Growth Jefferies 2014 Global Health Care Conference June 2014 Helen Torley, M.B. Ch. B., M.R.C.P. President and Chief Executive

More information

Disclosures of Interest. Publications Diabetologia Key points to emphasize

Disclosures of Interest. Publications Diabetologia   Key points to emphasize Disclosures of Interest No conflicts or disclosures How to Use the American Diabetes Association s Type 2 Diabetes Treatment Algorithm Rashida Downing, MD, FAAFP Primary Care Physician JenCare Medical

More information

REFERENCE CODE GDHC238DFR PUBLICAT ION DATE JULY 2013 EMPAGLIFLOZIN (TYPE 2 DIABETES) - FORECAST AND MARKET ANALYSIS TO 2022

REFERENCE CODE GDHC238DFR PUBLICAT ION DATE JULY 2013 EMPAGLIFLOZIN (TYPE 2 DIABETES) - FORECAST AND MARKET ANALYSIS TO 2022 REFERENCE CODE GDHC238DFR PUBLICAT ION DATE JULY 2013 EMPAGLIFLOZIN (TYPE 2 DIABETES) - Executive Summary Below table provides a summary of Empagliflozin for Type 2 diabetes in the 10 major pharmaceutical

More information

DARA Reports Year-End 2012 Financial Results

DARA Reports Year-End 2012 Financial Results April 1, 2013 DARA Reports Year-End 2012 Financial Results Company Provides a Commercial Portfolio and Development Pipeline Business Update RALEIGH, NC -- (MARKETWIRE) -- 04/01/13 -- DARA BioSciences,

More information

CURRENT CONTROVERSIES IN DIABETES CARE

CURRENT CONTROVERSIES IN DIABETES CARE CURRENT CONTROVERSIES IN DIABETES CARE Robert B. Baron MD MS Professor and Associate Dean UCSF School of Medicine Declaration of full disclosure: No conflict of interest Diabetes Mellitus: U.S. Impact

More information

REFERENCE CODE GDHC241DFR PUBLICAT ION DATE JULY 2013 FASIGLIFAM (TYPE 2 DIABETES) - FORECAST AND MARKET ANALYSIS TO 2022

REFERENCE CODE GDHC241DFR PUBLICAT ION DATE JULY 2013 FASIGLIFAM (TYPE 2 DIABETES) - FORECAST AND MARKET ANALYSIS TO 2022 REFERENCE CODE GDHC241DFR PUBLICAT ION DATE JULY 2013 Executive Summary Fasiglifam (TAK-875): Key Metrics in the 10 Major Pharmaceutical Markets* 2022 Market Sales US $508m 5EU $127m Japan $30m China $341m

More information

Incredible Incretins Abby Frye, PharmD, BCACP

Incredible Incretins Abby Frye, PharmD, BCACP Incredible Incretins Abby Frye, PharmD, BCACP Objectives & Disclosures Review the pathophysiology of T2DM and the impact of the incretin system Describe the defining characteristics of the available glucagonlike

More information

Liraglutide (Victoza) in combination with basal insulin for type 2 diabetes

Liraglutide (Victoza) in combination with basal insulin for type 2 diabetes Liraglutide (Victoza) in combination with basal insulin for type 2 diabetes May 2011 This technology summary is based on information available at the time of research and a limited literature search. It

More information

HALOZYME REPORTS SECOND QUARTER 2018 RESULTS

HALOZYME REPORTS SECOND QUARTER 2018 RESULTS Contacts: Robert H. Uhl Managing Director Westwicke Partners, LLC 858-356-5932 robert.uhl@westwicke.com Laurie Stelzer 858-704-8222 ir@halozyme.com FOR IMMEDIATE RELEASE HALOZYME REPORTS SECOND QUARTER

More information

Investor science event from ADA Orlando, 28 June 2010

Investor science event from ADA Orlando, 28 June 2010 Investor science event from ADA 2010 Orlando, 28 June 2010 Forward-looking statements This presentation contains certain forward-looking statements. These forward-looking statements may be identified by

More information

REPROS THERAPEUTICS. Dedicated to Treating Male and Female Reproductive Disorders. Corporate Presentation. August 2017

REPROS THERAPEUTICS. Dedicated to Treating Male and Female Reproductive Disorders. Corporate Presentation. August 2017 REPROS THERAPEUTICS Dedicated to Treating Male and Female Reproductive Disorders Corporate Presentation August 2017 Safe Harbor Any statements made by the Company that are not historical facts contained

More information

Financial results in line with expectations and important progress of the pipeline

Financial results in line with expectations and important progress of the pipeline Company Announcement - No. 37 / 2015 Zealand Interim report for H1 2015 (un-audited) Financial results in line with expectations and important progress of the pipeline Growing lixisenatide (Lyxumia ) royalty

More information

LATE BREAKING STUDIES IN DM AND CAD. Will this change the guidelines?

LATE BREAKING STUDIES IN DM AND CAD. Will this change the guidelines? LATE BREAKING STUDIES IN DM AND CAD Will this change the guidelines? Objectives 1. Discuss current guidelines for prevention of CHD in diabetes. 2. Discuss the FDA Guidance for Industry regarding evaluating

More information

National Horizon Scanning Centre. Saxagliptin (BMS ) for type 2 diabetes. April 2008

National Horizon Scanning Centre. Saxagliptin (BMS ) for type 2 diabetes. April 2008 Saxagliptin (BMS 477118) for type 2 diabetes This technology summary is based on information available at the time of research and a limited literature search. It is not intended to be a definitive statement

More information

Slide 1. Investor Presentaton Jefferies Global Healthcare Conference. New York, 7 June Shanghai part of Cities Changing Diabetes

Slide 1. Investor Presentaton Jefferies Global Healthcare Conference. New York, 7 June Shanghai part of Cities Changing Diabetes Slide 1 Investor Presentaton Jefferies Global Healthcare Conference New York, 7 June 2016 Shanghai part of Cities Changing Diabetes Slide 2 Forward-looking statements Novo Nordisk s reports filed with

More information

Slide 1. Welcome and strategy update. Lars Fruergaard Jørgensen President and CEO

Slide 1. Welcome and strategy update. Lars Fruergaard Jørgensen President and CEO Slide 1 Lars Fruergaard Jørgensen President and CEO Slide 2 Forward-looking statements Novo Nordisk s reports filed with or furnished to the US Securities and Exchange Commission (SEC), including the company

More information

Calliditas Therapeutics Q2 Report Webcast August 16, 2018, 10:00 Presenters: Renée Aguiar-Lucander, CEO Fredrik Johansson, CFO

Calliditas Therapeutics Q2 Report Webcast August 16, 2018, 10:00 Presenters: Renée Aguiar-Lucander, CEO Fredrik Johansson, CFO Calliditas Therapeutics Q2 Report 2018 Webcast August 16, 2018, 10:00 Presenters: Renée Aguiar-Lucander, CEO Fredrik Johansson, CFO Disclaimer Important information This presentation may contain certain

More information

SOLVAY GROUP London Morning Meeting. June 26, 2009

SOLVAY GROUP London Morning Meeting. June 26, 2009 SOLVAY GROUP London Morning Meeting June 2, 9 1 Our fenofibrate franchise Klaus Kirchgassler, MD Sr VP Solvay Pharmaceuticals 2 Summary of lipid lowering market performance in Value Growth vs. previous

More information

NOVO NORDISK. Analyst: Recommendation: HOLD DATE: Industry: Drug manufacturers

NOVO NORDISK. Analyst: Recommendation: HOLD DATE: Industry: Drug manufacturers NOVO NORDISK Analyst: Recommendation: HOLD DATE: 11.11.2015 Industry: Drug manufacturers Share price 375,00 DKK Homepage www.novonordisk.com Ticker NVO Number of shares (000) 2.563.800 Target price 406,14

More information

Sanofi Announces Results of ORIGIN, the World s Longest and Largest Randomised Clinical Trial in Insulin in Pre- and Early Diabetes

Sanofi Announces Results of ORIGIN, the World s Longest and Largest Randomised Clinical Trial in Insulin in Pre- and Early Diabetes PRESS RELEASE Sanofi Announces Results of ORIGIN, the World s Longest and Largest Randomised Clinical Trial in Insulin in Pre- and Early Diabetes Dublin, Ireland (15 June 2012) Sanofi presented results

More information

CURRENT ISSUES IN DIABETES MANAGEMENT

CURRENT ISSUES IN DIABETES MANAGEMENT CURRENT ISSUES IN DIABETES MANAGEMENT Robert B. Baron MD MS Professor and Associate Dean UCSF School of Medicine Declaration of full disclosure: No conflict of interest Diabetes Mellitus: U.S. Impact DIABETES

More information

Accelerating our business from peptides to patients

Accelerating our business from peptides to patients Accelerating our business from peptides to patients Jeffries Global Healthcare Conference London, 19 November 2015 Zealand Pharma A/S Disclaimer This presentation does not constitute or form part of and

More information

Building a Premier Oncology Biotech

Building a Premier Oncology Biotech Building a Premier Oncology Biotech August 208 Forward-Looking Statements All of the statements in this presentation that are not statements of historical facts constitute forward-looking statements within

More information

Jefferies Healthcare Conference June 6, 2018

Jefferies Healthcare Conference June 6, 2018 Jefferies Healthcare Conference June 6, 2018 Forward-Looking Statements Some of the statements included in this presentation, particularly those regarding the commercialization and ongoing clinical development

More information

Corporate Presentation

Corporate Presentation Carriers Injectable to oral Progressive/Practical Innovation Emisphere Products Corporate Presentation November 2015 Patients OTCBB: EMIS Safe Harbor Statement The statements in this presentation or oral

More information

Patrick J. Sullivan Chief Executive Officer. January 9, 2018 Investor Presentation

Patrick J. Sullivan Chief Executive Officer. January 9, 2018 Investor Presentation Patrick J. Sullivan Chief Executive Officer January 9, 2018 Investor Presentation Forward Looking Statement This presentation may contain forward-looking statements concerning Insulet's expectations, anticipations,

More information