2014 Year End Review

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1 End Review Transplants Kidney Kidney Pancreas Pancreas Liver Heart Number of Patients on WaitList as of.. 99 Number Of Patients 9 Kidney Kidney Pancreas Liver Heart

2 Organ Donor Statistics Atlantic Canada DBD Donors by Reporting Province of Death Number of Donors NS PE NB NL Atlantic Canada DBD Donors Per Million by Province Number of Donors NS PE NB NL Atl Can * DBD - Donation After Brain Death

3 DBD Donors by Age Number of Donors 9 9 <= s and s and s > s DBD Donors by Age (in percentage) Number of Donors % 9% % % % % % % % % % 9.%.%.%.%.%.9%.%.9%.%.9%.%.%.%.9%.%.%.%.%.9%.%.%.% 9.% 9.% 9 <= s and s and s > s

4 DBD Donors by Cause of Death Number of Donors 9 MVA (Motor Vehical Accident) Head Injury (Trauma) Suicide Cardio Vascular Anoxia/Hypoxia Spontaneous Intracranial Hemorrhage Cerebral Vascular Accident Other DBD Donors by Cause Of Death (9-) 9.%.%.%.%.%.%.% MVA (Motor Vehical Accident) Head Injury (Trauma) Suicide Cardio Vascular Anoxia/Hypoxia Spontaneous Intracranial Hemorrhage Cerebral Vascular Accident Other

5 DBD Donors by Blood Type Number of Donors 9 9 A B O AB DBD Donors by Gender Number of Donors Male Female

6 DBD Donors Organs Exported / Imported (-) Number of Donors Montreal Quebec MORE Ottawa MORE London MORE Toronto MORE Hamilton MORE Calgary MORE Edmonton Manitoba British Columbia USA Exported Liver Organs Imported Liver Organs Exp Heart Organs Imp Heart Organs

7 Liver Allocation (Import for High Status) Number of Imports /F F /F F /F F /F F /F F /F F 9 Montreal Quebec MORE Ottawa MORE London MORE Toronto MORE Hamilton MORE Calgary MORE Edmonton Manitoba British Columbia USA * See Appendix A for Medical Status Description Liver Allocation (Export for High Status) Number of Exports /F F /F F /F F /F F /F F /F F 9 Montreal Quebec MORE Ottawa MORE London MORE Toronto MORE Hamilton MORE Calgary MORE Edmonton Manitoba British Columbia USA * See Appendix A for Medical Status Description

8 Heart Allocation (Import for High Status) Number of Imports Status Status Status Status Status Status 9 Montreal Quebec MORE Ottawa MORE London MORE Toronto MORE Hamilton MORE Kingston MORE Calgary MORE Edmonton Manitoba British Columbia USA * See Appendix A for Medical Status Description Heart Allocation (Export for High Status) Number of Exports Status Status Status Status Status Status 9 Montreal Quebec MORE Ottawa MORE London MORE Toronto MORE Hamilton MORE Kingston MORE Calgary MORE Edmonton Manitoba British Columbia USA * See Appendix A for Medical Status Description

9 Renal Transplants Live vs DBD (n=) Number of Donors Live (n=) DBD (n=) DBD (n=) % Live (n=) %

10 Kidney / Kidney Pancreas Transplant Services Kidney / Kidney Pancreas Transplants Performed for Atlantic Canada Recipients 9 Kidney KP Atlantic Canada Kidney / Kidney PancreasTransplant Recipients by Province NS PE NB NL DBD Donor Live Related Donor

11 Kidney / Kidney Pancreas Transplants By Age At Transplant K KP K KP K KP K KP 9 9 K KP 9 K KP K KP 9 K KP > And <= s > And <= s > And <= s > Kidney / Kidney Pancreas Transplants by Primary Diagnosis Groups 9 Kidney Other (Chronic renal failure, tumors..) Congenital/Hereditary Diseases Diabetes Polycystic Kidneys Glomerulonephritis/Autoimmune Diseases Nephropathy - Drug Induced Renal Vascular Disease Pyelonephritis/Interstitial Nephritis

12 Kidney / Kidney Pancreas Transplants Diabetes Type I, Type II and Non-Diabetic Type I Type II Non-Diabetic Kidney / Kidney Pancreas Transplants By Gender 9 Male Female

13 Kidney / Kidney Pancreas Transplants by Dialysis Types 9 CAPD CCPD Home Hemodialysis Hospital Hemodialysis Satellite Hemodialysis Preemptive * CAPD - Continuous Ambulatory Peritoneal Dialysis * CCPD - Chronic Cyclic Peritoneal Dialysis

14 Kidney Wait List Deaths (Including Workups) in Atlantic Canada Number Of Deaths 9 Kidney / Kidney Pancreas Transplants By Blood Type K KP 9 K KP K KP K KP K KP K KP K KP K KP K KP 9 9 K KP K KP 9 A B O AB

15 Kidney / Kidney Pancreas Deceased Donor Transplants by HLA Matching Medical High Priority A, B, DR Mismatch B, DR Mismatch DR Mismatch Wait time All other Mismatches Kidney / Kidney Pancreas DBD Donor Transplants (n=9 ) by HLA Matching vs Wait Time (n=) % (n=) % HLA Matching Wait Time

16 Kidney Pancreas Transplants 9 Kidney Pancreas Transplants By Province 9 NS PE NB NL

17 Liver Transplant Services Liver Transplants Performed for Atlantic Canada Recipients 9 Liver Transplants By Province NS PE NB NL

18 Liver Transplants By Gender 9 9 Male Female Liver Transplants By Age At Transplant 9 9 > And <= s >= And <= s >= And <= s >

19 Liver Transplants By Medical Status At Transplant 9 - T - F - F Indications for Liver Transplants by Primary Diagnosis 9 Cirrhosis - Alcohol Cirrhosis - Alcohol Hepatocellular Carcinoma Viral Hepatitas Autoimmune Disease Fatty Liver Disease Others

20 Liver Patients MELD Score At Transplant Liver Patients MELD Score At Transplant >= And <= >= And <=9 >= * See Appendix A for MELD Score Description Liver Patient Wait List Deaths # of Deaths vs Total number on WaitList as of.. % % Percentage Deceased Percentage Live

21 Medical Status Appendix A Liver Medical Status Description At Home. T At Home with a liver tumor. In Hospital with stable condition. In ICU or equivalent care facility but not on mechanical support with either: (a) creatinine > umol/l and / or rising by > umol/l per day, or (b) grade or encephalopathy. F In ICU or equivalent care facility due to fulminant liver failure but not on mechanical support In ICU requiring mechanical ventilation. Death is considered imminent without liver transplantation. In ICU requiring mechanical ventilation due to fulminant liver failure including primary graft non-function. F Death is considered imminent without liver transplantation MELD Score Description The Model for End-Stage Liver Disease is a numerical scale that is currently used for liver allocation. The MELD score is based on a patient's risk of dying while waiting for a liver transplant, and is based on objective and verifiable medical data. The MELD score calculation uses: Serum Creatinine (mg/dl) ** Bilirubin (mg/dl) INR The MELD score is calculated using the following formula: MELD Score =.9 x Loge(creatinine mg/dl) +. x Loge(billirubin mg/gl) +.xloge(inr) +. x Multiply the score by and round to the nearest whole number. Disclaimer: Historical data contained in this report is subject to change

22 Cardiac Transplant Services Heart Transplants Performed for Atlantic Canada Recipients 9 Heart Transplants By Province 9 NS PE NB NL

23 Heart Transplants By Gender Male Female Heart Transplants By Age At Transplant 9 > And <= s > And <= s > And <= s >=

24 Heart Transplants by Primary Diagnosis 9 Valvular Heart Disease: Severe Lv Dysfunction Ischemic Heart Disease Dilated Cardiomyopathy (Viral ) Ischemic Cardiomyopathy Hypertrophic Cardiomyopathy Arrhythmogenic Right Ventricle Dysplasia End Stage Biventricular Heart Failure Cardiogenic Shock Congenital Heart Disease Acute Myocardial Infarction Idiopathic Cardiomyopathy Restrictive Cardiomyopathy Congestive Heart Failure Coronary Artery Disease Heart Transplants By Medical Status At Transplant 9 A - B * See Appendix B for Medical Status Description

25 Heart Transplants By Blood Type 9 A B O AB

26 Appendix B Medical Status Heart Medical Status Description At Home. In Hospital. A VAD or Intravenous Inotropes on ward or at home. B ICU - Continuous infustion of intravenous inotropes (high dose of one or more inotropes). ICU - Mechanical Ventilatory or Circulatory Support. Disclaimer: Historical data contained in this report is subject to change

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