DETECTION OF NON PROLIFERATIVE DIABETIC RETINOPATHY USING SVM METHOD

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1 DETECTION OF NON PROLIFERATIVE DIABETIC RETINOPATHY USING SVM METHOD 1. Lekshmi Sree.H.A, 2. Jeba Derwin.D, 3. Dr.S.Tamil Selvi 1. PG Scholar, 2. Assistant Professor-ECE, Arunachala College Of Engg For Women, Tamil Nadu,India. 3. Prof&Head ECE(PG),National Engineeing College,Kovilpatti 1, 2 ABSTRACT: Diabetic Retinopathy (DR) is a common symptom of diabetes which is one of the world s leading causes of blindness. The initial stage of DR is NPDR(Non Proliferative Diabetic Retinopathy). The later stage of DR is Proliferative Diabetic Retinopathy.Early detection of diabetic retinopathy is very important because it enables timely treatment that can ease the burden of the disease on the patients and their families by maintaining a sufficient quality of vision and preventing severe vision loss and blindness. This paper describes the automatic assessment technique for the diabetic retinopathy with new method that is SVM classifier and unsupervised learning method, which helps the diabetic to diagnosis the disease at the early stage for the prevention from the vision loss. recognize diabetic retinopathy based on features, such as blood vessel area, exudates, hemorrhages, microaneurysms and texture. There are many techniques and algorithms that helps to diagnose DR in retinal fundus images. Retinal fundus image consists of a network of blood vessels and an optic disc. The initial stage of DR is NPDR. The later stage of DR is Proliferative Diabetic Retinopathy. Ophthalmologists diagnose DR by either mere eye observation or using computerized systems with complex detection algorithms. This paper different techniques were presented which is used for detecting and classify the Non Proliferative Diabetic retinopathy( NPDR). Keywords: Diabetic Retinopathy, SVM classifier, Unsupervised learning method, Morphological Segmentation. Retinal Image. I. INTRODUCTION Diabetic Retinopathy(DR) is a common symptom of diabetes which is one of the world s leading causes of blindness. Diabetes is a chronic end organ disease that occurs when the pancreas does not secrete enough insulin or the body is unable to process it properly. Ophthalmologists 22 Lekshmi Sree.H.A, Jeba Derwin.D, Dr.S.Tamil Selvi Fig. 1: Color fundus image with anatomical structures and lesions annotated. II. CLASSIFICATION OF DIABETIC RETI NOPATHY Diabetic Retinopathy is mainly divided into two types.

2 They are Non Proliferative Diabetic Retinopathy and Proliferative Diabetic Retinopathy.ProliferativeDiabetic Retinopathy is further divided into three types. They are Vitreous hemorrhage, Traction retinal detachement Neovascular glaucoma.non Proliferative Diabetic Retinopathy is divided into five types. They are Microaneurysms, Retinal hemorrhages,hard exudates,macular edema,macular ischemia. Newly formed abnormal blood vessels develop along the surface of the retina and are very fragile. Their fragility can cause them to bleed, which can cause severe vision loss and even blindness. As these vessels proliferate, bleed and subsequently scar, they can detach the retina. These forms of retinal detachment pose unique challenges for the retinal surgeon. Another complication is the obstruction of the outflow path for fluid that is constantly being produced in the eye by newly formed blood vessels. This can lead to dangerously high pressures in the eye and is called neovascular glaucoma. Nonproliferative diabetic retinopathy, previously called background retinopathy, is the earliest stage of diabetic eye disease. Microscopic changes occur in the blood vessels of the eye in non- proliferative disease; however, the changes typically do not produce symptoms and are not visible to the naked eye. Non-proliferative disease progresses from mild to moderate to severe. As the disease progresses, hard exudates (accumulations of fluid that has leaked from blood vessels), abnormalities in the growth of microscopic blood vessels in the retina, and bleeding from the veins that feed the retina may occur. While non-proliferative diabetic retinopathy is not itself a sight-threatening condition, it can triggermacular oedema or macular ischaemia, which are other forms of diabetic retinopathy that may cause rapid vision loss at any stage of non-proliferative disease. In addition, the 23 Lekshmi Sree.H.A, Jeba Derwin.D, Dr.S.Tamil Selvi vascular changes that occur in nonproliferative retinopathy lead to retinal ischaemia (lack of blood flow to the retina) and trigger progression to sightthreatening proliferative disease. As the severity of non-proliferative retinopathy increases, the risk of developing sightthreatening proliferative diabetic retinopathy also increases. III. LITERATURE SURVEY Various papers are proposed different types of algorithms and different techniques are used to classify the retinal image. Most of the papers are used supervised learning method. The disadvantage of this method is the segmented image is compared to the original reference image. Hence large time is needed.different types of detection methods are kernel PCA, Gaussian DD, PCA DD,Rotational symmetric method,lesion segmentationalgorithm,wavelettransforms,pro babilisticneuralnetworks,rotationalhomograph y are used.kernel PCA method the major disadvantage is background estimation error is present.pca DD and Gaussian DD method the detection accuracy is low.lesion segmentation algorithm,wavelet transform and Rotational homography method the main disadvantage is high noise is present. These classifiers are produce low accuracy for the classification.in existing techniques neural networks is used it is very complex method. Manual detection is time consuming process. Many researchers have made number of attempts to improve accuracy, predictivity, sensitivity and specificity. The lesion segmentation algorithm produce better performance but thickering of the retina calculation is difficult. The development of low cost and versatile Computer Aided Diagnosis (CAD) systems, which can be used in clinical environments, have drawn much more attention in recent years. In this method accuracy is very low.

Optical coherence tomography (OCT) is a noninvasive objective diagnostic technique that has become a powerful method for the clinical assessment of diabetic retinopathy. But large time is needed. IV.

3 Optical coherence tomography (OCT) is a noninvasive objective diagnostic technique that has become a powerful method for the clinical assessment of diabetic retinopathy. But large time is needed. IV. PROPOSED METHODOLOGY In this paper SVM classifier is used to classify the retinal image and also unsupervised method, median filter and morphological segmentation is used. PREPROCESSING Collection of retinal image Pre processing Feature Extraction Segmentation Classification Disease Detection Fig.2:Flow of work characteristic to the micro image structure within it, this structure typically being viewed in terms of the small texture primitives composing it. Typical applications include morphological segmentation of vegetation types in aerial photographs, segmentation of text and halftones in document pages, and medical imaging applications (like the extraction of bone tissue according to trabecular structure in magnetic resonance images). SVM CLASSIFIER SVM algorithm is applied to produce the classification parameters.classification parameter is used to classify the images.svm models search for a hyperplane that can linearly separate classes of objects.to fit nonlinear curves to the data SVM make use of a kernel function.kernal function is used to map the data in to different space.svm can be applied to non- linear classification using non linear kernal function. V. EXPERIMENTS AND RESULTS The different types of filters and classification techniques are used to identify the disease.these techniques about how these were designed and implemented using MATLAB software. Preprocessing is commonly involves removing low frequency background noise and normalizing the intensity of the individual particles of images.this method is used to enhancing data images prior to computation processing. MORPHOLOGICAL SEGMENTATION In texture segmentation, an image is partitioned into regions, each of which is dened by some set of features Fig.3:Input image 24 Lekshmi Sree.H.A, Jeba Derwin.D, Dr.S.Tamil Selvi

micro image structure. This structure is typically being view in terms of the small texture primitives composing it. Fig.

It is particularly effective at removing salt and pepper type noise.

The pattern of neighbours is called the "window", which slides, pixel by pixel over the entire image. Fig.

4 micro image structure. This structure is typically being view in terms of the small texture primitives composing it. Fig.4:Median filtered image Median filtering is a nonlinear method used to remove noise from images. It is widely used as it is very effective at removing noise while preserving edges. It is particularly effective at removing salt and pepper type noise. The median filter works by moving through the image pixel by pixel, replacing each value with the median value of neighbouring pixels. The pattern of neighbours is called the "window", which slides, pixel by pixel over the entire image. Fig.6:SVM Output Support Vector Machine (SVM) is primarily a classier method that performs classification tasks by constructing hyperplanes in a multidimensional space that separates cases of different class labels. SVM supports both regression and classification tasks and can handle multiple continuous and categorical variables. For categorical variables a dummy variable is created with case values as either 0 or 1. This paper SVM classifier is used to classify the given fundus image is normal or abnormal. VI. CONCLUSION Fig.5:Morphological segmentation In morphological segmentation, an image is divided into regions, each of which is dened by some set of features characteristic to the 25 Lekshmi Sree.H.A, Jeba Derwin.D, Dr.S.Tamil Selvi Early detection of diabetic retinopathy is very important because it enables timely treatment that can ease the burden of the disease on the patients and their families by maintaining a sufficient quality of vision and preventing severe vision loss and blindness. Positive economical benefits can be achieved with early detection of Diabetic retinopathy because patients can be more productive and can live without special medical care. Image processing and analysis algorithms are important because they enable

5 development of automated systems for early detection of Diabetic retinopathy. In existing method various classifiers are used to detect the disease.the existing method supervised techniques are used, that is the segmented image is compared to the manually segmented reference image.hence large time is needed.major disadvantage of supervised learning method is difficuilty and cost of selecting training sites. This paper, unsupervised technique and SVM classifier are used. In unsupervised technique, no extensive prior knowledge is required.the SVM classifier produced good accuracy when compared to other classifiers. VII. REFERENCES [1] Akara Sopharak, Bunyarit Uyyanonvara, Sarah Barman, and Thomas H Williamson, Automatic detection of diabetic retinopathy exudates from non-dilated retinal images using mathematical morphology methods. Computerized Medical Imaging and Graphics, vol. 32, no. 8, pp , Dec [2] A D Fleming, K A Goatman, and S Philip, The role of haemorrhage and exudate detection in automated grading of diabetic retinopathy, British Journal of Ophthalmology, August [3] G G Gardner, D Keating, T H Williamson, and A T Elliott, Automatic detection of diabetic retinopathy using an artificial neural network: a screening tool, Br J Ophthalmol, vol. 80, no. 11, pp , Nov [4] M Garcia, C I Sanchez, M I Lopez, D Abasolo, and R Hornero, Neural network based detection of hard exudates in retinal images., Comput Methods Programs Biomed, vol. 93, no. 1, pp. 9 19, Jan [5] H Li and O Chutatape, Automated feature extraction in color retinal images by a model based approach, IEEE Transactions on Biomedical Engineering, vol. 51, no. 2, Feb Lekshmi Sree.H.A, Jeba Derwin.D, Dr.S.Tamil Selvi [6] Inan Guler and Elif Derya U beyli, Multiclass Support Vector Machines for EEG- Signals Classification,IEEE Transactions On Information Technology In Biomedicine, vol. 11, no. 2, March, [7] R A Kirsch, Computer determination of the constituent structure of biological images., Computers and Biomedical Research, vol. 4, no. 3, pp , Jun [8] Lili Xu, Shuqian Luo, Support Vector Macidne Based Method For Identifying Hard Exudates In Retinal Images, IEEE, [9] M. Larsen, J. Godt, N. Larsen, H. Lund- Andersen, A.K. Sjolie, E. Agardh, H. Kalm, M.Grunkin, D.R. Owens, Automated detection of fundus photographic red lesions in diabetic retinopathy, Investigative Ophthalmology & Visual Science 44 (2) (2003) [10] Nageswara Rao Pv, Uma Devi T, Dsvgk Kaladhar,Gr Sridhar, Allam Appa Rao, A Probabilistic Neural Network Approach Forprotein Superfamily Classification, Journal of Theoretical and Applied Information Technology. [11] M Niemeijer, B van Ginneken, J Staal, M S A Suttorp- Schulten, and M D Abramoff, Automatic detection of red lesions in digital color fundus photographs, IEEE Trans Med Imag, vol. 24, no. 5, pp , [12] A Osareh, M Mirmehdi, B Thomas, and R Markham, Automated identification of diabetic retinal exudates in digital colour images, British Journal of Ophthalmology, vol. 87, no. 10, pp , Oct [13] Priya.R, Aruna.P, Automated Classification System For Early Detection Of Diabetic Retinopathy In Fundus Images, International Journal Of Applied Engineering Research, Dindigul, Volume 1, No 3,2010.

Implementation of Automatic Retina Exudates Segmentation Algorithm for Early Detection with Low Computational Time

www.ijecs.in International Journal Of Engineering And Computer Science ISSN: 2319-7242 Volume 5 Issue 10 Oct. 2016, Page No. 18584-18588 Implementation of Automatic Retina Exudates Segmentation Algorithm