2016 Canadian League Against Epilepsy Meeting

Transcription

1 Draft Program 2016 Canadian League Against Epilepsy Meeting October 14 16, 2016 Hotel Pur Quebec, Quebec City Meeting Objectives To learn about the etiology, diagnosis, and management of psychogenic nonepileptic seizures, SUDEP, and post-traumatic epilepsy. To discuss the up-to-date management of epilepsy. Learn about the different advances in neuroimaging and EEG techniques in the assessment of patients with epilepsy. To become familiar with the latest developments in cognition related to epilepsy To learn about the latest and emerging basic science and clinical research discoveries in the field of epilepsy. To learn about basic concepts about statistics and genetics as it relates to epilepsy. To enhance interactions among health professionals and researchers in varied disciplines of epilepsy. To learn about the current state of epilepsy care across the country. Friday October 14, :00 p.m. Conference Registration 5:00 p.m. CLAE Annual General Meeting Salon AB 5:55 p.m. Welcome Dr. Nathalie Jetté, CLAE President 6:00 p.m. Presidential Lecture Dr. Jorge Burneo, Incoming CLAE President

2 6:30 p.m. Canadian EPILEPSY Alliance / Alliance canadienne de L'EPILEPSIE Achievements & Challenges 7:00 p.m. Plenary Session TITLE (PNES) Dr. Markus Reuber, University of Sheffield : 8:00 p.m. Wrap up for the day Saturday October 15, :30 a.m. CLAE Fun Run/Walk Join us for the inaugural CLAE Fun Run/Walk! 7:30 a.m. Registration and Breakfast 8:30 a.m. Plenary session Salon AB Psychogenic Non-Epileptic Seizures Dr. Jose Tellez-Zenteno, University of Saskatchewan 10:15 a.m. Break and Exhibits 10:30 a.m. Breakout sessions Session 1 Salon A Is Marijuana Useful for the Treatment of Epilepsy in Adults? Chair: Richard McLachlan, Western University

3 Learn the history and politics of marijuana use. Learn the basic science of the endocannabinoid system. Learn the evidence for efficacy and toxicity of marijuana. Learn how medical marijuana is prescribed in Canada. Epileptologists, neurologists, fellows, residents, nurses, patient advocates. History of Marijuana and Seizures Richard McLachlan, Western University Physiology and Pharmacology of Cannabis Dr. Mac Burnham, University of Toronto Case for Medical Marijuana in Epilepsy Dr. Jose Tellez-Zenteno, University of Saskatchewan Case against Medical Marijuana in Epilepsy Dr. Mark Sadler, Dalhousie University Session 2 Salon B Bad Seizures but Non-Diagnostic MRI What to do? Chair: Andrea Bernasconi, McGill University Identify the clinical challenges associated with the pre-surgical evaluation of non diagnostic MRI. Learn the newest non-invasive imaging techniques allowing to characterize brain structure and function. Learn the MRI characteristics of subtle, often overlooked epileptogenic lesion. Learn the role of MRI in accelerating referrals to specialized epilepsy centers. Epileptologists, neurologists, neurosurgeons, neuroradiologists, neuropsychologists, neuroscientists, fellows, residents, nurses.

4 Advanced Structural MRI: Converting Negative to Positive MRI Dr. Neda Ladbon-Bernasconi, McGill University Non-Structural Evidence of Seizure Focus: the Role of Functional Imaging Dr. Paolo Federico, University of Calgary The Importance of Assessing White Matter Integrity: The Role of Diffusion Imaging Dr. Donald Gross, University of Alberta Linking Histology to in Vivo MRI Dr. Ali Khan, Western University 12:15 p.m. Lunch and Exhibits 12:30 p.m. Poster Tour Salon C 1:30 p.m. Trainee Platform Presentations (Top four trainee abstracts) Location TBA 2:30 p.m. Breakout sessions Session 3 Salon A Statistics Course Chairs: Dr. Colin Josephson, University of Calgary and Dr. Boris Bernhardt, McGill University Neurologists, researchers, neuropsychologists, neuroscientists, fellows, residents. Lies, Damned Lies, and Statistics Dr. Boris Bernhardt, McGill University Systematic Reviews and Meta Analysis

5 Dr. Colin Josephson, University of Calgary Statistical Analysis for Neuroimaging Data Dr. Seok-Jun Hong, McGill University Big Data Analysis and Machine Learning Dr. Jordan Engbers, University of Calgary Session 4 Salon B Post-Traumatic Seizures and Epilepsy Chair: Dr. Aylin Reid, University of Toronto To review the diagnosis and management of early post-traumatic seizures. To review the epidemiology, clinical presentation, and risk factors for post-traumatic epilepsy. To discuss the diagnostic work-up of patients with post-traumatic epilepsy. To discuss medical and surgical approaches in treating post-traumatic epilepsy. To review mechanistic factors and experimental treatments being investigated in animal models of post-traumatic epilepsy. Neurologists, neurosurgeons, basic scientists, residents, fellows, nurses. Post-Traumatic Seizures and Epilepsy in the Developing Brain Dr. Michael Esser, University of Calgary Clinical Management of Post-Traumatic Epilepsy Dr. Jorge Burneo, Western University Surgical Management of Post-Traumatic Epilepsy Dr. David Steven, Western University Experimental Models of Post-Traumatic Epilepsy Dr. Aylin Reid, University of Toronto 4:15 p.m. Break and Exhibits

6 4:30 p.m. Breakout sessions Session 5 Salon A Cognition in Epilepsy: New Insights Chairs: Dr. Marilyn Jones-Gotman, McGill University and Dr. Mary Pat McAndrews, University of Toronto To become familiar with new research regarding the following aspects of cognition in children and adults with epilepsy: the incidence and type of cognitive deficits associated with new onset epilepsy; cognitive deficits and aging; the nature and implications of accelerated long term forgetting; social cognition; and an approach to remediating cognitive deficits. Neuropsychologists, epileptologists, neurologists, family physicians, pediatricians, nurses, social workers, clinical psychologists, clinical researchers. Cognition in New Onset Epilepsy (in Adults and Children) Dr. Antonina Omisade, Nova Scotia Health Authority and Dr. Nicole Taylor, University of Manitoba Effects of Long-Term Epilepsy and of Temporal-Lobe Resection on Cognitive Aging Dr. Marilyn Jones-Gotman, McGill University Accelerated Long Term Forgetting (in Adults and Children) Dr. Mary Pat McAndrews, University of Toronto and Dr. Mary Lou Smith, University of Toronto Social Cognition: An Under-Assessed Area in Epilepsy Dr. Melanie Cohn, University of Toronto Cognitive Remediation and Short-Term Outcomes in Children Dr. Elizabeth Kerr, University of Toronto

7 Session 6 Salon B Looking Inside the Brain: From Intracerebral EEG to Non-Invasive Methods Chair: Dr. Franҫois Dubeau, McGill University Learn about normal intracerebral EEG patterns. Learn about the interpretation of intracerebral EEG in its traditional form. Learn about new developments in intracerebral EEG (high frequency oscillations). Learn about the EEG-fMRI technique. Clinical epileptologists, neurophysiologists, clinical researchers. The Normal Intracerebral EEG in Different Brain Regions Dr. Birgit Frauscher, Queen s University Analyzing and Interpreting the Seizure Onset in Intracerebral EEG Dr. Philippe Kahane, University of Grenoble When Can Interictal Activity Be a Sufficient Marker of the Epileptogenic Zone Dr. Richard Wennberg, University of Toronto New Intracranial EEG Markers: HFOs, Very Slow Activity Dr. Jean Gotman, McGill University Can EEG-fMRI Tell Us What the Intracerebral EEG Will Find? Dr. Hui Ming Khoo, McGill University 6:15 p.m. Wrap up for the day 7:00 p.m. Reception and Dinner (Tickets must be purchased in advance)

8 Sunday October 16, :00 a.m. Breakfast 7:15 a.m. Salon A/B Challenging Surgical and Seizure Semiology Cases Chairs: Dr. David Stevens, Western University and Dr. Mark Sadler, Dalhousie University : Describe the diagnostic work-up for patients being considered for epilepsy surgery List the reasons for failure of epilepsy surgery. Describe the diagnostic work-up in patients who have failed previous epilepsy surgery. : Neurologists, neurosurgeons, neuropsychologists, residents and fellows in neurology and neurosurgery : Case 1 Dr. Alain Bouthillier, Université de Montréal Case 2 Dr. Walter Hader, University of Calgary 8:30 a.m. Plenary Session Salon AB SUDEP Dr. Elizabeth Donner, University of Toronto 10:15 a.m. Break and Exhibits 10:30 a.m. Breakout sessions

9 Session 7 Salon A Genetics Course Chair: Dr. Danielle Andrade, University of Toronto and Dr. Patrick Cossette, Montreal Session 8 Salon B Why Do Seizures Start and Stop? Chair: Dr. Peter Carlen, University of Toronto To appreciate the EEG measured dynamics of seizure onset and offset. To appreciate the many relevant cellular and local network properties and activities related to seizure phases. To appreciate the relevance of brain metabolic changes that can lead to and result from seizure activity both in relationship to seizure onset and seizure termination. To consider how our understanding of seizure onset and offset can lead to better preventative and therapeutic strategies. Clinicians, neuroscientists. Intra- and Extracranial EEG Dynamics in Relationship to Seizure States and Strategies for Modulating Seizure Activities Dr. Berj Bardakjian, University of Toronto Neuronal and Ionic Dynamics in Relation to Seizure Onset and Termination Dr. Igor Timofeev, Université Laval Local Neuronal Network Involvement in Seizure Onsets and Offsets Dr. Massimo Avoli, McGill University Presynaptic Mechanisms Determining Seizure Onset and Offset

10 Dr. Peter Carlen, University of Toronto Metabolic and Glia Changes in Relationship to Seizure Phases Dr. Paolo Bazzigaluppi, Toronto Western Hospital 12:15 p.m. Wrap up and completion of participant evaluation 12:30 p.m. Boxed Lunch 12:30 p.m. Sponsor Lunch (invite only)