Biology 323 Human Anatomy for Biology Majors Week 10; Lecture 1; Tuesday Dr. Stuart S. Sumida. Cranial Nerves and Soft Tissues of the Skull

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1 Biology 323 Human Anatomy for Biology Majors Week 10; Lecture 1; Tuesday Dr. Stuart S. Sumida Cranial Nerves and Soft Tissues of the Skull

2 FOREBRAIN MIDBRAIN HINDBRAIN

3

4 Forebrain: Cerebrum Perception, movement of somatopleure, sensoro-motor integration, emotion, memory, learning. Diencephalon Homeostasis, behavioral drives in hypothalamus; sensory relay and modification in thalamus; melatonin secretion in pineal gland. Midbrain (Mesencephalon) Control of eye movement. Hindbrain Cerebellum and Pons control of movement, proprioreceptive input; relays visual and auditory reflexes in pons. Medulla Oblongata Involuntry functions: blood pressure, sleep, breathing, vomiting.

5 Development Special Sense organs = nose, eyes and ears, begin as small outcrops of ectoderm called placodes

6 Development Placode 1 = nose Placode 2 = eye Placode 3 = ear

7 Development In the nose, the ectoderm become nerve cells that send their fibres through the cribriform plate of the ethmoid, back to the brain This is Cranial Nerve I = the Olfactory Nerve

8 Development

9 Development

10 Development The second placode becomes the lens of the eye. It sinks below the surface of the skin, and an outgrowth of the brain wraps around it. The outgrowth is the retina, and the stalk connecting it is Cranial Nerve II = The Optic Nerve

11 Development

12 Development The Inner ear starts out as a lens, but turns into a fluid filled sac Receptor organs of hearing and balance. Cranial Nerve VIII = Auditory or Vestibulocochlear Nerve

13 Development

14 Development Head somites can be divided into 2 sets. Pre-otic and post-otic

15 Development The sklerotomes of the post otic somites help form the floor of the brain case

16 Development.and their myotomes develop into muscles of the tongue

17 Development The myotomes of the pre-otic somites form the muscles that move the eyeballs.

18 Development Each is supplied by a different cranial nerve:

19 Development Cranial Nerve III = Occulomotor Nerve

20 Development Cranial Nerve IV = Trochlear Nerve

21 Development Cranial Nerve VI = Abducens Nerve

22 Gill Arch Derivatives Development

23 Mandibular arch Development

24 Cranial Nerve V: The Trigeminal Nerve (3 branches) V1 Opthalmic, V2 Maxillary, V3 Mandibular

25 Hyoid arch Development

26 Cranial Nerve VII: Facial nerve

27 Next arch Development

28 Cranial nerve IX: Glossopharyngeal Nerve

29 Remaining arches Development

30 Cranial nerve X: The Vagus Nerve

31 The Cranial Nerves Summary of Cranial Nerves

32 Is there a #0 nerve? The Nervus Terminalis (Nerve Zero) has been suggested as a primitive vertebrate structure serving the vomeraonasal organ.

33 Special Sensory Nerves

34

35 Cranial Nerve I The Olfactory Nerve Sensory Smell Cribriform plate of ethmoid

36

37

38

39 Introduction to eye proper

40 Cranial Nerve II The Optic Nerve Sensory Vision Optic foramen

41 Ventral Root Cranial Nerves

42

43 Cranial Nerve III The Occulomotor Nerve Mainly motor Eye Movement Superior orbital fissure

44 Cranial Nerve III The Occulomotor Nerve Mainly motor Eye Movement Superior orbital fissure

45 Detail on Occulomotor (III) Function: Motor to all extra-ocular muscles except lateral rectus and superior oblique. Parasympathetic innervation to sphincter pupillae and ciliaris muscles (synapse in ciliary ganglion). Sympathetic innervation to sphincter pupillae and ciliaris muscles. Fibers originate in upper thoracic levels, synapse in cervical ganglia, get to orbit via associated arteries.

46 Opthalmic nerve pathways

47

48 Cranial Nerve IV The Trochlear Nerve Mainly motor Superior oblique Superior orbital fissure

49 Superior oblique Cranial Nerve IV

50

51 Cranial Nerve VI The Abducens Nerve Mainly motor Lateral rectus Superior orbital fissure

52 Lateral rectus Cranial Nerve VI

53 SUPERIOR ORBITAL FISSURE AND STRUCTURES PASSING THROUGH IT. III IV VI V1 Opthalmic v. 1 Opth. a. V2 Sphenoid/ anterior view of orbital surface and sutures with frontal, ethmoid and palatine bones/ cranial nerves indicated

54

55 Cranial Nerve XII The Hypoglossal Nerve Mainly Motor Tongue Hypoglossal Canal

56 Dorsal Root Cranial Nerves

57

58 Cranial Nerve V The Trigeminal Nerve Both V 1 = ophthalmic V 2 = maxillary V 3 = mandibular

59 Cranial Nerve V 1 Ophthalmic division Sensory Superior orbital fissure

60 Opthalmic and maxillary nerve pathways/lateral view

61 Opthalmic and maxillary nerve pathways/medial view of lateral cut away orbit Lateral path of efferent parsympathetics from VII to lacrimal gland following zygomatico-temporal n. V2 to lacrimal n. V3

62 Cranial Nerve V 1 Ophthalmic division Sensory Superior orbital fissure

63 Detail on Ophthalmic (V-1) Function: Almost wholly sensory: eyeball, lacrimal gland, conjunctiva, part of nasal mucosa, from brow ridge superiorly. Carrys a bit of sympathetic fibers for dilator pupillae. From upper thoracic levels, synapsing in in upper cervical ganglion. Reaches via branches of internal carotid artery.

64 Cranial Nerve V 2 Maxillary division Sensory Foramen rotundum

65 Cranial Nerve V 2 Maxillary division Sensory Foramen rotundum

66 Cranial Nerve V 3 Mandibular division Both Foramen ovale

67 Cranial Nerve V 3 Mandibular division Both Foramen ovale Sensory Component

68 Detail on Mandibular (V-3) Function: Sensory to lower jaw region, including teeth. Motor nerve to muscles of the mandibular arch: masseter, temporalis, anterior and posterior pterygoids, mylohyoid, tensor tympani, anterior digastric, and tensor veli palatini. The auriculotemporal branch contains secretomotor fibers to the parotid gland via the parotid branches.

69 Cranial Nerve V

70

71 Cranial Nerve VII The Facial Nerve Both Motor and sensory

72 Cranial Nerve VII The Facial Nerve Both motor and sensory Muscles of facial expression Parasympathetic: Lacrimal ducts, taste, salivary glands

73 Cranial Nerve VII The Facial Nerve VII a VII b VII c VII d VII e Temporal Zygomatic Buccal Mandibular Cervical

74 Cranial Nerve VII Enter skull via internal auditory meatus

75 Cranial Nerve VII Exit skull via stylomastoid foramen

76 Cranial Nerve VII a Temporal b Zygomatic c Buccal d Mandibular e Cervical

77 Detail on Facial (VII) Function: Motor to muscles of the hyoid arch: posterior digastric, mm. of facial expression. Sends parasympathetic fibers via greater petrosal branch and pterygopalatine ganglion to lacrimal gland (secretomotor fibers). It may also supply parasympathetic innervation to palatine, pharyngeal, and nasal glands.

78 An Evolutionary Branch of VII

79 Cranial Nerve VIII Vestibulocochlear Nerve Sensory Hearing Internal Auditory Meatus

80

81 Cranial Nerve IX The Glossopharyngeal Nerve Both Pharynx, posterior tongue Jugular foramen

82 Cranial Nerve IX The Glossopharyngeal Nerve Both Pharynx, posterior tongue Jugular foramen

83 Detail on Glossopharyngeal (IX) Function: Motor to stylopharyngeus muscle. Parasympathetic secretomotor fibers to parotid gland. Sensory to pharynx, tonsils, and posterior 1/3 of tongue. Taste fibers for posterior 1/3 of tongue.

84

85 Cranial Nerve X The Vagus Nerve Both Throat to end of midgut Jugular foramen

86 Cranial Nerve X The Vagus Nerve Both Throat to end of midgut Jugular foramen

87 An Evolutionary Branch of X

88 Cranial Nerve XI The Accessory Nerve Mainly Motor larynx, pharynx, trapezius and sternocleidomastoid Foramen Magnum

89 Names

90 I II III IV V VI VII VIII IX X XI XII Olfactory Optic Occulomotor Trochlear Trigeminal Abducens Facial Vestibulochochlar Glossopharyngeal Vagus Accessory Hypoglossal

91 Motor, sensory, or both

92 I II III IV V VI VII VIII IX X XI XII Sp. Sense Sp. Sense Ventral Rt. Ventral Rt. Dorsal Rt. Ventral Rt. Dorsal Rt. Sp. Sense Dorsal Rt. Dorsal Rt. Dorsal Rt. Ventral Rt. Sensory Sensory Mainly motor Mainly motor Both Mainly motor Both Sensory Both Both Mainly motor Mainly motor

93 Route

94 I II SENSORY SENSORY Cribriform plate Optic Canal

95 III IV V VI MAINLY MOTOR MAINLY MOTOR BOTH MAINLY MOTOR Superior orbital fissure Superior orbital fissure Superior orbital fissure Superior orbital fissure

96 III IV V VI MAINLY MOTOR MAINLY MOTOR BOTH MAINLY MOTOR Superior orbital fissure Superior orbital fissure Superior orbital fissure Superior orbital fissure

97 III IV V VI MAINLY MOTOR MAINLY MOTOR BOTH V1 V2 V3 MAINLY MOTOR Superior orbital fissure Superior orbital fissure Superior orbital fissure Foramen Rotundum Foramen Ovale Superior orbital fissure

98 VII BOTH Internal Auditory meatus VIII SENSORY Internal Auditory meatus

99 VII VIII B SENSORY Internal Auditory meatus Exits through stylomastoid foramen Internal Auditory meatus

100 IX X BOTH BOTH Jugular foramen Jugular foramen

101 XI XII MAINLY MOTOR MAINLY MOTOR Foramen Magnum Hypoglossal Canal

102 Functional Summary (Note other details)

103 I OLFACTORY SENSORY CRIBRIFORM PLATE SMELL

104 II OPTIC SENSORY OPTIC CANAL Vision

105 III OCCULOMOTOR MAINLY MOTOR SUPERIOR ORBITAL FISSURE Focusing

106 IV TROCHLEAR MAINLY MOTOR SUPERIOR ORBITAL FISSURE Superior obliques

107 V TRIGEMINAL BOTH SUPERIOR ORBITAL FISSURE Ophthalmic, FORAMEN OVALE maxillary, FORAMEN ROTUNDUM mandibular

108 VI ABDUCENS MAINLY MOTOR SUPERIOR ORBITAL FISSURE Lateral rectus

109 VII FACIAL BOTH INTERNAL AUDITORY MEATUS Temporal Zygomatic EXITS THROUGH STYLO- MASTOID FORAMEN Buccal Mandibular Cervical

110 VIII AUDITORY SENSORY INTERNAL Hearing AUDITORY MEATUS

111 IX GLOSSO PHARYNGEAL BOTH JUGULAR FORAMEN Taste, saliva, throat

112 X VAGUS BOTH JUGULAR Motor and Sensory. FORAMEN Parasympathetic from throat to end of midgut

113 XI ACCESSORY MAINLY MOTOR FORAMEN MAGNUM Trapezius, sternocleidomastoid, throat

114 XII HYPOGLOSSAL MAINLY MOTOR HYPOGLOSSAL CANAL Tongue and throat

115 Meninges (All from Neural Crest) Outermost: Dura mater Middle: Arachnoid mater Deepest: Pia mater Cerebrospinal fluid between Arachnoid and Pia mater

116 Meninges: Dura mater

117 Dural Reflections Falx cerebri Tentorium cerebelli

118 Vasculature: Venus Sinuses

119 Vasculature: Venus Sinuses

120 Vasculature: Venus Sinuses

121 Vasculature: Arterial Supply

122 Vasculature: Arterial Supply

123

124 Jaw Moving Musculature:

125 Jaw Opening Musculature: Diagastric Muscle Anterior belly innervated by Mandibular (V3) nerve Posterior belly innervated by Facial (VII) nerve

126 Note! Stylohyoid, styloglossus, tongue muscles in general.

127 Superficial Facial Muscles (all innervated by VII)

128 Some muscles of mastication (Innervated by V3) Deeper Facial Muscles (All innervated by VII)

129 Tongue: Surface

130 Extrenisc and Intrensic Tongue Muscles

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