Headaches. Mini Medical School. November 10, A. Laine Green MSc, MD FRCP(C) Assistant Professor Department of Medicine (Neurology)

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1 Headaches. Mini Medical School. November 10, 2016 A. Laine Green MSc, MD FRCP(C) Assistant Professor Department of Medicine (Neurology)

2 Artist Agnes Cecile

3

4 Disclosures I have received an honorarium from and/or acted as a consultant for: Tribute Pharmaceuticals Cambia (diclofenac potassium for oral solution) Allergan Canada BOTOX (onabotulinumtoxina) Cartoon by Dan Wasserman US News & World Report

5

6 How do Neurologists Think??

7 4 questions Is the problem neurological? Where is the problem? Brain, brainstem, cerebellum, spinal cord, nerve root, peripheral nerve, muscle What is causing the problem? What are we going to do about it?

8 Additional 2 questions in Headache cases

9 How common are headaches Headaches are very common Tension Headache most common > 50% of the population Migraine - lifetime prevalence Female = 25% Male = 10% Gender preference Pre-puberty F > M Post-puberty F >>> M (3:1) Estrogen Exception Cluster Headache M > F 10% of the Population 9 has Migraine!!!!

10 Burden of Headache 10% of population have migraine Up to 4% have headache more than half the days of the month Direct medical costs $1,000,000,000/yr million lost school or work days/year Indirect costs may be double the direct costs

11 Chronic Migraine 0.9% and 1.4% of the population 11,678 in Nova Scotia Less than 1/3 work full time 1 in 5 can t work Use a lot of resources Family MD, specialist visits, pain clinic visits, ERs $1,884 per patient per year $22 million a year to the Nova Scotia health care system

12 Invisible disease

13

14 Classification International Classification of Headache Disorders Over 300 types of headaches Two main types Primary Secondary trauma, vascular, substance, infection, psychiatric Subtypes Episodic Chronic 14

15 The Headaches Tension Migraine And related Cluster And other similar Secondary

16 Secondary Headaches Serious or ominous And not so

17 Diagnosis History Physical

18 History How long? Attacks or continuous frequency Details about the headache Details Details

19 Details Location Severity Quality Duration Recurrence Associated symptoms Nausea/Vomiting Face changes Warning Triggers Aggravating factors Activity Light Sound Smell Effect of sleep Menstrual cycle Pill effects Hormone replacement therapy

20 Details Sleep disorder Caffeine Head/neck injuries TMJD/Bruxism Brain infections Anxiety Depression Fibromyalgia Other pain Abuse history Other specialists Tests done to date Other medical problems Family history Smoking/alcohol Job FUNCTION

21 Details on Treatments

22 Concerning features Signs of infection Weight change Cancer HIV Other body systems Focal neurological deficits Thunderclap Headache Change in Headache Headaches that change with position Headaches that start with bending, lifting, coughing, sneezing Progressive vision loss

23 Tension Type Headache

24 Tension Type Headache (TTH) Most common primary headache May be not the most common you will see Also called Muscle contraction headaches Stress headaches Ordinary Essential 24

25 Tension Type Headache Last 30 minutes to 7 days Both sides of head Pressing or tightening quality Not throbbing Mild or Moderate intensity Not worse with routine activity No nausea No vomiting May be light sensitive May be sound sensitive 25

26 Migraine

27 Migraine Last 4-72 hours One side of head Throbbing Moderate or severe intensity Worse with routine activity Nausea and/or vomiting Light and sound sensitive May be smell sensitive

28 Migraine with Aura Headache as described before Aura before headache Sometimes with Sometimes without headache Usually a visual phenomenon Lasts 5-60 minutes Reversible Person goes back to normal Can be sensory Can be speech Very rarely weakness

29 Cortical Spreading Depression

30

31 Cluster

32 Cluster Headache Also known as Suicide Headache Uncommon 0.1% lifetime prevalence Onset yrs Male >>> Female Risk heavy smoking Precipitants alcohol, histamine, nitroglycerin Coarse facial features Seasonal and clockwise periodicity Same time of year Same time of night (often within 90 mins of sleep onset)

33 Leonine Facial Features

34 Cluster Headache Last 15 minutes to 3 hours minutes Up to 8 per day 1-2 most common Severe or Very severe pain in or around the eye One sided Red eye, tearing eye Runny congested nose Swollen eye Red face Muffled hearing Droopy eye lid Small pupil Don t like to be still!

35 Thunderclap Headache

36 Treatment

37 Contributing Factors Sleep disorders Sleep apnea TMJ and bruxism Anxiety or mood disorders Other pain disorders Other medical disorders Stressors Caffeine

38 Patient education Diagnosis Medications Trouble shooting Goal setting Patient Satisfaction = Reality Expectations Headache diary Absolutely essential Medication side effects Implications of disorder Migraine with aura in women doubles their stroke risk! Medication Overuse

39 Treatment Lifestyle Non pharmacologic Acute Treatments Preventative Treatments >4 headaches per month Removing/modifying things that are counter productive Follow up

40 Treatment Lifestyle Diet Well balanced, good choices, all food groups No skipping meals Exercise Stress reduction Trigger identification and avoidance Hydration with water Avoid caffeine Sleep hygiene

41 Non Drug Treatments Heat Cold Rest decrease environmental stimulus Acupuncture Massage Biofeedback Cognitive Behavior Therapy Other As long it is helpful As long as it is not harmful As long as poverty is not a side effect

42 Medications When you have a headache Help prevent headaches >4 headaches per month Less frequent Less severe Do nothing for an individual headache attack Transitional treatments

43 Medication Overuse To be avoided

44 Other Treatments

45 Nerve Blocks Injections of anesthetic +/- steroids

46 Botox Chronic Migraine

47 Non Invasive Nerve Stimulators

48

49 Invasive Nerve Stimulators

50 Challenges in Headache Treatment Triptans only specific medicine Medicines with other intended purposes Anti-Seizure Anti-depressants Blood pressure Alzheimer s Efficacy Side effects

51 Removal of Non-Helpful Things Caffeine Caffeine Caffeine Any acute medication being overused Appropriate limits

52 Vent Starbucks =12 cans coca cola =2 medium Tim Hortons

53 Headache is kind of a big deal!

54 Live as if you were to die tomorrow. Learn as if you were to live forever. -M.K. Gandhi

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