Subject Index. Canaloplasty aqueous outflow system evaluation 110, 111 complications 118, 119 historical perspective 109, 110

Transcription

1 Subject Index Ab externo Schlemm canal surgery, see Canaloplasty, Viscocanalostomy Ab interno Schlemm canal surgery, see istent, Trabectome Adjustable sutures 14, 15 AGV glaucoma drainage implants 43, 44 Angle closure glaucoma surgery argon laser peripheral iridoplasty overview 140, 141 technique 141 cyclodestructive procedures 143, 144 glaucoma drainage implant 143 goniosynechialysis 142 indications 137 iridectomy 140 laser peripheral iridotomy overview 138 technique lens extraction 142 cataract extraction combination 154 overview 143 Anterior chamber, hypotonic flat 53, 54 Antifibrotic therapy, see also 5-Fluorouracil, Mitomycin C 84, 85 glaucoma drainage implants 44 Moorfields Safer Surgery System agent types 7 complication risk factors 9 conjunctival clamp application 10, 11 conjunctival/sub-tenon pocket 10 duration of treatment 7, 10 single-dose regimen 9 sponge delivery 10, 11 sub-tenon/subscleral flap 10 novel compounds 85, 86 scleral flap sutures adjustable sutures 14, 15 function and types 12 laser suture lysis 12, 13 placement 12 releasable sutures 13, 14 removal principles 12 Argon laser peripheral iridoplasty overview 140, 141 technique 141 Astigmatism, complication prevention and Benzalkonium chloride conjunctival 65, 69 deep ocular effects 70 Bevacizumab, wound healing modulation 86 BG glaucoma drainage implants 42, 44 Bleb early leak 52 encapsulation and fibrosis 58, 59 late leaks 62 leak prevention and management 24 overdrainage 23, 24 remodeling 59, 60 cystic bleb 4, 5 needling revision with antifibrotic agents 85 postoperative evaluation Bleeding, complication prevention and management 20 Canaloplasty aqueous outflow system evaluation 110, , 119 historical perspective 109,

2 limitations 119, 120 mechanism 120 outcomes 116, 117 patient selection 113, 115 prospects surgical technique Carbon dioxide laser-assisted sclerotomy CAT-152, wound healing modulation 85, 86 Cataract deep sclerectomy combination with extraction 151 glaucoma surgery combination 148, 149 intraocular pressure effects of extraction istent combination with extraction phacoemulsification and 149, 150 postoperative complication prevention and Trabectome combination with extraction , 151 combination with extractions 154 Choroidal effusion, complication prevention and management 24, 54 Ciliary body shutdown, complication prevention and management 24 Confocal microscopy, see In vivo confocal microscopy Conjunctival clamp, antifibrotic agent delivery 10, 11 Conjuctival tear, complication prevention and management 19, 20 angle closure glaucoma surgery 143, 144 endoscopic cyclophotocoagulation 180, 181 indications 175 lasers 176, 177 outcomes 179, 180 prospects 181 techniques overview 173, outcomes 169, 170 overview 168 techniques 168 transscleral cyclophotocoagulation 180, 181 indications 174, 175 lasers and techniques 175, 176 outcomes 179 prospects 181 Decompression retinopathy, complication prevention and management 21, 22 Deep sclerectomy advantages 29, 30, 34 cataract surgery combination 151 indications 30, 31 nonpenetrating deep sclerotomy , 106 outcomes 34 technique Drainage devices, see Glaucoma drainage implant, Ex-PRESS Mini-Glaucoma Device Drainage implant, see Glaucoma drainage implant Endoscopic cyclophotocoagulation, see Ex-PRESS Mini-Glaucoma Device outcomes 93, 94 overview 91, 92 surgical technique 92, 93 Failure rate, glaucoma surgery preoperative assessment 71, 72 risk factors 80 trends 70, 71 5-Fluorouracil administration mechanism of action 83 Moorfields Safer Surgery System 7 needling revision of blebs 85 83, 84 Fornix-based conjunctival flap 3 5, 18 Glaucoma drainage implant angle closure glaucoma surgery 143 antifibrotic therapy 44 cataract surgery combination , 45 historical perspective 37 indications 37, 38 pathophysiology , 166 outcomes 166, 167 overview 164 technique 164, 165 Subject Index 185

3 surgical technique basic technique 38, 39 ciliary sulcus placement 41 pars plana placement 40, 41 quadrant placement 39, 40 tube coverage 41 comparison 38 types comparison of types 43, 44 nonvalved implants 42 valved implants 43 Glaucoma filtration surgery, see Deep sclerectomy, Laser surgery, Pediatric glaucoma, Postoperative management, external filtering surgery, Trabeculectomy Goniopuncture, intraocular pressure rise management 60, 61 Gonioscopic ab interno penetrating laser sclerostomy 98, 99 Goniosynechialysis, angle closure glaucoma surgery 142 Goniotomy, 158, 159 outcomes 159 overview 157, 158 technique 158 Histopathology, glaucoma Impression cytology glaucoma findings postoperative changes 72, 73 Infection, complication prevention and management 22, 23 Intraocular pressure cataract extraction effects postoperative management high 55, 56, 60 low 51, 52 titration in Moorfields Safer Surgery System 17 In vivo confocal microscopy postoperative findings 72, 74 preservative-induced conjunctival impairment 69 Iridectomy, angle closure glaucoma surgery 140 istent cataract extraction combination device 127 in vitro studies 129, 130 outcomes 132, 133 prospects 135, 136 surgical technique 128 theory 129 Krupin valve implant 43 Laser cyclophotocoagulation, see Laser iridoplasty, see Argon laser peripheral iridoplasty Laser peripheral iridotomy overview 138 technique Laser surgery biological tissue effects 97 carbon dioxide laser-assisted sclerotomy Er:YAG laser 99, 100, laser trabecular ablation 101 mitomycin C use 100, 101, 104, 106 Nd:YAG laser , 176 nonpenetrating filtering surgery overview 96, 97 penetrating filtering surgery Laser suture lysis, scleral flap sutures 12, 13, 57, 68 Lens, extraction 142 Limbal-based conjunctival flap 2 5, 17 Malignant glaucoma/aqueous misdirection, complication prevention and management 24, 25, 55, 56 Mitomycin C, see also Antifibrotic therapy 84, 85 glaucoma drainage implant use 44 laser surgery use 100, 101, 104, 106 mechanism of action 80, 81 needling revision of blebs 85 administration 81, 82 Moorfields Safer Surgery System 7, 23 outcomes 82 tube surgery and nonpenetration surgery use 83 Molteno glaucoma drainage implants 42 Moorfields Safer Surgery System antifibrotic agents complication risk factors 9 conjunctival clamp application 10, 11 conjunctival/sub-tenon pocket 10 duration of treatment 7, Subject Index

4 single-dose regimen 9 sponge delivery 10, 11 sub-tenon/subscleral flap 10 types 7 closure 17 astigmatism 25 bleb leak 24 bleb overdrainage 23, 24 bleeding 20 cataract 25 choroidal effusion 24 ciliary body shutdown 24 conjunctival tear 19, 20 decompression retinopathy 21, 22 infection 22, 23 malignant glaucoma/aqueous misdirection 24, 25 ptosis 25 scleral flap damage 20, 21 strabismus 25 suprachoroidal hemorrhage 21 visual field loss 22 vitreous loss 22 wound leak 23 conjunctival flap 5, 6 conjunctival incision 3 5 corneal traction suture 3, 4 filtration area positioning 3 fluid flow control paracentesis 14 infusion 14, 15 fornix-based approach 6 intraocular pressure titration 17 limbal-based approach 6 peripheral iridectomy 16, 17 postoperative medication 18 scleral flap 6, 7 scleral flap sutures adjustable sutures 14, 15 function and types 12 laser suture lysis 12, 13 placement 12 releasable sutures 13, 14 removal principles 12 sclerostomy initial incision 16 manual block removal 16 punch sclerostomy 16, 17 Nonpenetrating deep sclerotomy , 106 Ocular massage 57 Overfiltration, complication prevention and management 52, 53 Paracentesis, Moorfields Safer Surgery System 14 Pediatric glaucoma angle surgery combined trabeculotomy/ 162 comparison of techniques 161, 162 goniotomy 158, 159 outcomes 159 overview 157, 158 technique 158 ab externo 160 outcomes 160, 161 technique 159, 160 cyclodestructive procedures 169 outcomes 169, 170 overview 168 techniques 168 filtering surgery comparison of techniques 167, 168 glaucoma drainage devices 165, 166 outcomes 166, 167 overview 164 technique 164, , 164 outcomes 164 technique 163 Peripheral iridectomy, Moorfields Safer Surgery System 16, 17 Phacoemulsification, combination 149, 150 Postoperative management, external filtering surgery complication management, see also specific anterior chamber, hypotonic flat 53, 54 bleb early leak 52 encapsulation and fibrosis 58, 59 late leak 62 remodeling 59, 60 choroidal effusion 54 Subject Index 187

5 goniopuncture intraocular pressure rise 60, 61 intraocular pressure high 55, 56, 60 low 51, 52 late 61, 62 malignant glaucoma 55, 56 overfiltration 52, 53 recognition 50, 51 internal ostium obstruction 56, 57 factors promoting and opposing filtration 49 laser suture lysis 57, 58 ocular massage 57 ocular surface changes 72, 73 releasable sutures 57, 58 standard postoperative therapy 50 Pseudopemphigoid, drug induction 67 Ptosis, complication prevention and Releasable sutures 13, 14 Scarring prevention, see Antifibrotic therapy risk factors in glaucoma filtration surgery 8 wound healing mechanisms 79, 80 Schlemm s canal surgery, see Canaloplasty, istent, Trabectome, Viscocanalostomy Scleral flap damage, complication prevention and management 20, 21 Sclerostomy, Moorfields Safer Surgery System initial incision 16 manual block removal 16 punch sclerostomy 16, 17 Strabismus, complication prevention and Suprachoroidal hemorrhage, complication prevention and management 21 Trabectome cataract extraction combination , 151 histological outcomes 127 outcomes 129, 130 prospects 135, 136 surgical technique 126 Trabecular bypass, see istent Trabeculectomy, see also Moorfields Safer Surgery System angle closure glaucoma surgery cataract extraction combination 154 overview 143 failure rate 71 5-fluorouracil use 83, 84 glaucoma drainage implant comparison 38 historical perspective 1, 2, 29 internal approach, see Trabectome internal ostium obstruction 56, 57 mitomycin C administration 81, 82 outcomes 82 combined trabeculotomy/ 162 filtering surgery 163, 164 outcomes 164 technique 163 ab externo 160 outcomes 160, 161 technique 159, 160 phacoemulsification and 149, 150 viscocanalostomy outcome comparison 115, 116 Transscleral cyclophotocoagulation, see Tube Versus Trabeculectomy study 2, 38, 45 Viscocanalostomy aqueous outflow system evaluation 110, , 119 historical perspective 109, 110 limitations 119, 120 mechanism 120 outcomes 115 patient selection 113, 115 prospects surgical technique outcome comparison 115, 116 Visual field loss, complication prevention and management 22 Vitreous loss, complication prevention and management 22 Wound healing mechanisms 79, 80 novel modulators 85, 86 Wound leak, complication prevention and management Subject Index