UPPER RESPIRATORY TRACT INFECTIONS. IAP UG Teaching slides

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1 UPPER RESPIRATORY TRACT INFECTIONS 1

2 INTRODUCTION Most common problem in children below 5 years. In this age group they get about 6 8 episodes per year. It includes infections of nasal cavity, throat, nasopharynx, ears, sinuses. 2

3 ACUTE PHARNYNGITIS Nasopharyngitis: Nasal symptoms are more prominent. Tonsillopharyngitis: Throat symptoms are more prominent 3

4 ETIOLOGY Viruses: rhinoviruses, influenza, parainfluenza, corona, adenoviruses are common. Bacterial: Group A beta hemolytic streptococci, (GABHS) is commonest. Others are H. influenza, C.diptheriae. 4

5 CLINICAL FEATURES Fever Running nose Sore Throat Conjuctival congestion Pain in deglutition Cough Depending on the presenting symptoms one should try to differentiate between viral & bacterial etiology, even though exactly not possible. 5

6 ACUTE PHANYNGITIS 6

7 VIRAL Acute onset, Red eyes Rhinorrhea Exanthema, Diarrhea may be present. Cough more prominent. Pharyngeal exudates & cervical lymphadenopathy less often Indicates involvement of more than one mucus membrane 7

8 BACTERIAL Acute onset, pain in throat, little nasal discharge & less cough More pharyngeal congestion, thick exudates, patchy tonsils & tender cervical lymphadenopathy 8

9 COMPLICATIONS Suppurative: Retropharyngeal abscess, peritonsilar abscess, otitis media, mastoiditis, sinusitis. Nonsuppurative: Acute rheumatic fever & acute glomerulonephrits. 9

10 DIAGNOSIS Diagnosis is essentially clinical Blood count, ESR, CRP level can help but have a low predictive value 10

11 Throat culture is gold standard but a positive result does not reliably distinguish acute streptococcal pharyngitis from asymptomatic carriage. Rapid antigen detection test (RADTS) is also available. ASO has NO role in diagnosis of acute pharyngitis as it takes several weeks to become positive. 11

12 Supportive treatment TREATMENT Rest, antipyretics, normal saline nasal drops, sometimes first generation antihistaminics for troublesome coryza. 12

13 SPECIFIC TREATMENT Viral pharyngitis does not need antimicrobial treatment GABHS is self limiting disease but antibiotics are given to prevent morbidity & mortality. 13

14 Penicillin is the drug of choice But Amoxicillin is a good alternative & widely used 40 mg/kg/day is given for 10 days. Erythromycin, Azithromycin and First Generation Cephalosporins can also be given. 14

15 TONSILLECTOMY Indicated only if seven or more infections of the tonsils per year 15

16 ACUTE SUPPURATIVE OTITIS MEDIA OTITIS MEDIA is defined as inflammation of the middle ear. Children are more prone for ASOM because, the Eustachian tubes communicating throat with ears are straight & short 16

17 TYPES 1. Acute otitis media (AOM) 2. Chronic supportive otitis media (CSOM) 3. Recurrent otitis media: Three or more episodes of AOM in six months, 4 or more in one year. 17

18 ETIOLOGY BACTERIA: Streptococcus pneumonia, Haemophilus influezae Moraxella catarrhalis VIRUSES: RSV, Influenza. 18

19 DIAGNOSIS Diagnosis is done by clinical examination by Otoscope 19

20 OTOSCOPE The eardrum is inflamed & tense. The eardrum is inflamed & tense. 20

21 COMPLICATIONS Two major complication 1. Pyogenic Meningitis 2. Deafness 21

22 TREATMENT It is treated with Antibiotics Amoxicillin (40mg /kg/ day ) If severe 3 rd Generation Cephalosporins are used. 22

23 Treatment is continued for complete 10 days to prevent complications & chronicity. For relief of pain, paracetomol is used. No role of local antibiotic drugs in ASOM. 23

24 Partially treated or untreated cases may lead to middle ear effusion (MEE) MEE if not monitored can give rise to DEAFNESS. To avoid this TYMPANOMETRY is done every two weekly till it resolves Sometimes TYMPANOCENTESIS is needed 24

25 ACUTE SINUSITIS In children Maxillary & Ethmoid sinuses are fully developed at birth. The Sphenoid sinus by 3 years & Frontal sinus at 7 to 8 years. So infection of sinuses is common & associated by NASOPHARYNGITIS 25

26 26

27 27

28 CLINICAL FEATURES Nasal Congestion Purulent Nasal Discharge Fever Cough Halitosis Headache and Facial pain rare in children 28

29 TREATMENT Amoxycillin or Amoxy clav 40mg / kg / day or 3 rd generation cephalosphorins if severe. Treatment should be given for 14 days or 1 week beyond symptom resolution. 29

30 Thank You 30

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