Imaging Perineural Spread in the Head &
|
|
- Arthur Berry
- 5 years ago
- Views:
Transcription
1 Imaging Perineural Spread in the Head & Neck Tumours Vincent Chong, MD MBA FRCR Professor Department of Diagnostic Imaging National University Health System Singapore Overview: Perineural Spread Review some key concepts Surgical pathology Clinical implications Recognizing perineural spread Directly (neural involvement) Indirectly (denervation changes) 1
2 Perineural Involvement: Surgical Pathology Perineural infiltration (local disease) 36% major resections Most cases, tumour confined to 1 cm of affected nerve Perineural spread (beyond primary site) Distal spread >2 cm is unusual Grave prognostic implications Perineural Infiltration (Local): Adenoid Cystic Carcinoma 2
3 Perineural Infiltration (Local): Adenoid Cystic Carcinoma 3
4 4
5 Perineural Spread (Beyond Primary Tumour) Perineural Spread (Beyond Primary Tumour) Mastoid C2 5
6 Summary: Perineural Involvement Surgical Pathology Perineural Spread Versus Perineural Infiltration Nerve Involvement: Histopatholgy Tumour concentrated at margins Anoxia & infarcts in nerve trunks Myelin and axonal degenerate 6
7 Why Perineural Spread? Mechanical Explanation #1 Proximity of neural (rail) network #2 Path of least resistance Growth Factor Binding Sites: Chemical Explanation Axon Nerve growth factor Neural cell adhesion molecule (N-CAM) N-CAM 95% of adenoid cystic Ca 93% of SCCa Hutcheson et al. Neural cell adhesion expression in adenoid cystic carcinoma. Laryngoscope 2000; 110: Vural E et al. Correlation of neural cell adhesion molecules with perineural spread of squamous cell carcinoma of the head and neck. Otolaryn Head Neck Surg 2000; 122:
8 Growth Factor Binding Sites: Chemical Explanation Schwann cells Growth factor receptor p75 Desmoplastic melanomas Adenoid cystic carcinomas Basal cell carcinoma Iwamoto S et al. Evidence that p75 neurotrophin receptor mediates perineural spread of desmoplastic melanoma. J Am Acad Dermatol 1996; 35: Chang PC et al. Perineural spread of malignant melanoma of the head and neck. AJNR 2004; 25:5-11 Mechanical Explanation? Chemical Explanation? 8
9 Mechanical Explanation? Chemical Explanation? Clinical Significance: Prognosis Independent predictor of local recurrence Primary tumour biologically more aggressive 30% decrease in 5-year survival rate 3x increase in local recurrence 9
10 Detecting of PNS If this patient has perineural spread, where would you look? 1. Palatine canals 2. Pterygopalatine fossa 3. Both Detecting of PNS 10
11 11
12 Hard Palate Carcinoma 12
13 Hard Palate Carcinoma Hard Palate Carcinoma 13
14 Hard Palate Carcinoma: PNS usually seen as a recurrence 14
15 Hard Palate Carcinoma: PNS usually seen as a recurrence #Antegrade & Retrograde Spread: Lingual & Inferior Alveolar Nerves M Pterygoid M Lingual N Patient with submandibular gland muco-epidermoid carcinoma, operated, presented with paraesthesia over chin 15
16 #Antegrade & Retrograde Spread: Lingual & Inferior Alveolar Nerves #Antegrade & Retrograde Spread: Lingual & Inferior Alveolar Nerves 16
17 4/10/2013 #Antegrade & Retrograde Spread: Lingual & Inferior Alveolar Nerves #Antegrade & Retrograde Spread: Lingual & Inferior Alveolar Nerves 17
18 #Antegrade & Retrograde Spread: Lingual & Inferior Alveolar Nerves #Antegrade & Retrograde Spread: Lingual & Inferior Alveolar Nerves 18
19 Why does denervated muscle enhance? Why does denervated muscle enhance? Increased perfusion Vasodilatation due to decreased sympathetic tone Total capillaries remain the same Capillaries per unit mass of muscles increase ( overvascularization ) Carpenter S, Karpati G. Necrosis of capillaries in denervation atrophy of human muscle. Muscle Nerve 1982; 5: Hudlicka O. Do changes in the vascular bed contribute to the development of denervation atrophy in skeletal muscles? Basic Applied Myology 2007; 17:
20 Conclusion: Perineural Spread Surgical Pathology Perineural infiltration (local disease) Perineural spread (beyond primary site) Histopathology Tumour concentrated at nerve margins Anoxia & infarcts in nerve trunks Conclusion: Imaging PNS Nerve Thickened nerve Foraminal erosion Muscle changes Atrophy Contrast enhancement 20
Neuroradiology Case of the Day
Neuroradiology Case of the Day 76 th CAR Annual Meeting, Montreal, Quebec April 27, 2013 Eugene Yu, MD Assistant Professor of Radiology and Otolaryngology-Head and Neck Surgery Head and Neck Imaging Princess
More informationARTICLE. Imaging the cranial nerves in cancer
Cancer Imaging (2004) 4, S1 S5 DOI: 10.1102/1470-7330.2004.0006 CI ARTICLE Vincent Chong Department of Diagnostic Radiology, Singapore General Hospital, Outram Road, Singapore 169608, Singapore Corresponding
More informationPerineural Tumor Spread. In Head & Neck Cancer
Head and Neck Imaging Conference University of Perineural Tumor Spread In Head & Neck Cancer Philip Chapman MD University of Alabama, Birmingham OBJECTIVES: 1. Define (PNTS) 2. Distinguish from pathologic
More informationManagement of Salivary Gland Malignancies. No Disclosures or Conflicts of Interest. Anatomy 10/4/2013
Management of Salivary Gland Malignancies Daniel G. Deschler, MD Director: Division of Head and Neck Surgery Massachusetts Eye & Ear Infirmary Massachusetts General Hospital Professor Harvard Medical School
More informationPerineural Tumor Spread (PNS) Perineural Tumor Spread (PNS) PNS Anatomic Considerations. Perineural Tumor Spread-Imaging
Imaging of Perineural Tumor Spread in Head and Neck Cancer Lawrence E. Ginsberg, MD Departments of Diagnostic Radiology and Head and Neck Surgery University of Texas M.D. Anderson Cancer Center Houston,
More informationWorld Journal of Colorectal Surgery
World Journal of Colorectal Surgery Volume 6, Issue 5 2016 Article 9 Basal Cell Cancer Carcinoma of the anus: Case Reports and Review of the Literature Christopher Dwyer MD Marc Brozovich MD, FACS, FASCRS
More informationThe Pterygopalatine Fossa: Postoperative MR Imaging Appearance
AJNR Am J Neuroradiol 21:1315 1319, August 2000 The Pterygopalatine Fossa: Postoperative MR Imaging Appearance Ling-Ling Chan, June Chong, Ann M. Gillenwater, and Lawrence E. Ginsberg BACKGROUND AND PURPOSE:
More informationImaging: When to get MRI, CT or PET-CT?
Imaging: When to get MRI, CT or PET-CT? Alina Uzelac, D.O. Assistant Clinical Professor Neuroradiology UCSF Department of Radiology and Biomedical Imaging San Francisco General Hospital Overview CT MRI
More informationRefresher Course EAR TUMOR. Sasikarn Chamchod, MD Chulabhorn Hospital
Refresher Course EAR TUMOR Sasikarn Chamchod, MD Chulabhorn Hospital Reference: Perez and Brady s Principles and Practice of radiation oncology sixth edition Outlines Anatomy Epidemiology Clinical presentations
More information04/09/2018. Salivary Gland Pathology in the Molecular Era Old Friends, Old Foes, & New Acquaintances
Salivary Gland Pathology in the Molecular Era Old Friends, Old Foes, & New Acquaintances Jennifer L. Hunt, MD, MEd Aubrey J. Hough Jr, MD, Endowed Professor of Pathology Chair of Pathology and Laboratory
More informationParotid Disease Case Discussions. Valerie Jefford November 28, 2002
Parotid Disease Case Discussions Valerie Jefford November 28, 2002 Case 1 44 y.o. man referred with lump anterior to R ear. Q1 What do you want to know? no pain 2 years but bigger now Smoker Q2 What to
More informationCase Scenario 1. 7/13/12 Anterior floor of mouth biopsy: Infiltrating squamous cell carcinoma, not completely excised.
Case Scenario 1 7/5/12 History A 51 year old white female presents with a sore area on the floor of her mouth. She claims the area has been sore for several months. She is a current smoker and user of
More informationORIGINAL ARTICLE. head and neck cancer frequently necessitates combined extracranial and intracranial approaches
ORIGINAL ARTICLE The Sensitivity and Specificity of High-Resolution Imaging in Evaluating Perineural Spread of Adenoid Cystic Carcinoma to the Skull Base Ehab Hanna, MD; Emre Vural, MD; Emmanuel Prokopakis,
More informationEasily detected signs of perineural tumour spread in head and neck cancer
Insights into Imaging (2018) 9:1089 1095 https://doi.org/10.1007/s13244-018-0672-8 PICTORIAL REVIEW Easily detected signs of perineural tumour spread in head and neck cancer Jan Willem Dankbaar 1 & Frank
More informationInternational Journal of Pharma and Bio Sciences MUCOEPIDERMOID CARCINOMA OF MINOR SALIVARY GLAND-PALATE: ABSTRACT
Case report Biosciences International Journal of Pharma and Bio Sciences ISSN 0975-6299 MUCOEPIDERMOID CARCINOMA OF MINOR SALIVARY GLAND-PALATE: SHIVAKUMAR.S 1 AND SUBAIR VC 2 1 Professor, Department of
More information(CYLINDROMA) ATLAS OF HEAD AND NECK PATHOLOGY ADENOID CYSTIC CARCINOMA
(CYLINDROMA) This malignant tumor is poorly encapsulated and while seemingly well defined within the affected gland, there is usually infiltration of surrounding tissue on closer examination. The cut surface
More informationCase Scenario. 7/13/12 Anterior floor of mouth biopsy: Infiltrating squamous cell carcinoma, not completely excised.
Case Scenario 7/5/12 History A 51 year old white female presents with a sore area on the floor of her mouth. She claims the area has been sore for several months. She is a current smoker and user of alcohol.
More informationPhysician to Physician AJCC 8 th Edition. Head and Neck. Summary of Changes. AJCC Cancer Staging Manual, 7 th Ed. Head and Neck Chapters
Physician to Physician Head and Neck William M. Lydiatt, MD Chair of Surgery Nebraska Methodist Hospital Clinical Professor of Surgery, Creighton University Validating science. Improving patient care.
More informationCranial Nerve VII - Facial Nerve. The facial nerve has 3 main components with distinct functions
Cranial Nerve VII - Facial Nerve The facial nerve has 3 main components with distinct functions Somatic motor efferent Supplies the muscles of facial expression; posterior belly of digastric muscle; stylohyoid,
More informationLecture 07. Lymphatic's of Head & Neck. By: Dr Farooq Amanullah Khan PMC
Lecture 07 Lymphatic's of Head & Neck By: Dr Farooq Amanullah Khan PMC Dated: 28.11.2017 Lymphatic Vessels Of the 800 lymph nodes in the human body, 300 are in the Head & neck region. The lymphatic vessels
More informationCase 2. Dr. Sathima Natarajan M.D. Kaiser Permanente Medical Center Sunset
Case 2 Dr. Sathima Natarajan M.D. Kaiser Permanente Medical Center Sunset History 24 year old male presented with a 3 day history of right flank pain, sharp in nature Denies fever, chills, hematuria or
More information(loco-regional disease)
(loco-regional disease) (oral cavity) (circumvillae papillae) (subsite) A (upper & lower lips) B (buccal membrane) C (mouth floor) D (upper & lower gingiva) E (hard palate) F (tongue -- anterior 2/3 rds
More informationJournal of International Academy of Forensic Science & Pathology (JIAFP)
Journal of International Academy of Forensic Science & Pathology (JIAFP) ISSN 2395-0722 MICROCYSTIC ADNEXAL CARCINOMA-A CASE REPORT WITH REVIEW OF LITERATURE Case Report Sulakshana M S 1,Natarajan M 2
More informationUnknown Cases from the Participants
Unknown Cases from the Participants Case 1: 1 Case 1: Case 1: DDX? Answer on next slide Case 1: MS V5 Neuropathy Case 2: Case 2: 76 year old woman Ultrasound for multinodular goiter finds suspicious nodule
More informationThe International Federation of Head and Neck Oncologic Societies. Current Concepts in Head and Neck Surgery and Oncology
The International Federation of Head and Neck Oncologic Societies Current Concepts in Head and Neck Surgery and Oncology www.ifhnos.net The International Federation of Head and Neck Oncologic Societies
More informationOropharyngeal cancer
Cancer Imaging (2005) 5, S52 S57 DOI: 10.1102/1470-7330.2005.0030 CI MULTIDISCIPLINARY SYMPOSIUM: HEAD & NECK CANCER Monday 3 October 2005, 14:00 16:00 Oropharyngeal cancer Robert Hermans Department of
More informationCatholic University of Louvain, St - Luc University Hospital Head and Neck Oncology Programme. Anatomopathology. Pathology 1 Sept.
Anatomopathology Pathology 1 Anatomopathology Biopsies Frozen section Surgical specimen Peculiarities for various tumor site References Pathology 2 Biopsies Minimum data, which should be given by the pathologist
More informationMalignant growth Maxilla management an analysis
ISSN: 2250-0359 Volume 3 Issue 2 2013 Malignant growth Maxilla management an analysis *Balasubramanian Thiagarajan *Geetha Ramamoorthy *Stanley Medical College Abstract: Malignant tumors involving maxilla
More informationPatterns of perineural spread of head and neck malignancies.
Patterns of perineural spread of head and neck malignancies. Poster No.: C-1234 Congress: ECR 2014 Type: Educational Exhibit Authors: C. Martins Jarnalo, G. Lycklama à Nijeholt, E. Sanchez-Aliaga, 1 1
More informationProstate cancer ~ diagnosis and impact of pathology on prognosis ESMO 2017
Prostate cancer ~ diagnosis and impact of pathology on prognosis ESMO 2017 Dr Puay Hoon Tan Division of Pathology Singapore General Hospital Prostate cancer (acinar adenocarcinoma) Invasive carcinoma composed
More informationSALIVARY GLAND DISEASES. Omar alnoubani MD,MRCS
SALIVARY GLAND DISEASES Omar alnoubani MD,MRCS Salivary Glands Overview Parotid gland Sublingual gland Submandibular gland Salivary glands - Types 3 Major Salivary Glands Parotid Submandibular Sublingual
More informationChapter 7 Part A The Skeleton
Chapter 7 Part A The Skeleton Why This Matters Understanding the anatomy of the skeleton enables you to anticipate problems such as pelvic dimensions that may affect labor and delivery The Skeleton The
More informationLesions Mimicking Adenoid Cystic Carcinoma. Diagnostic Problems in Salivary Gland Pathology An Update 5/29/2009
Diagnostic Problems in Salivary Gland Pathology An Update Lesions Mimicking Adenoid Cystic Carcinoma Stacey E. Mills, M.D. W.S. Royster Professor of Pathology Director of Surgical and Cytopathology University
More informationRare Presentation Of Adenoidcystic Carcinoma Of External Auditory Canal With Subcutaneous Metastasis In Temporal Region
ISPUB.COM The Internet Journal of Otorhinolaryngology Volume 13 Number 2 Rare Presentation Of Adenoidcystic Carcinoma Of External Auditory Canal With Subcutaneous Metastasis In Temporal Region S Kaushik,
More informationMR and CT anatomy and the pathology of skull base focusing on pterygopalatine fossa
MR and CT anatomy and the pathology of skull base focusing on pterygopalatine fossa Poster No.: C-1688 Congress: ECR 2010 Type: Educational Exhibit Topic: Head and Neck Authors: S. Kandatsu, R. Kishimoto,
More informationCutaneous Adnexal Tumors
Cutaneous Adnexal Tumors Lesions with Predominant Follicular Differentiation Special Emphasis on Basal Cell Carcinoma 2014-04-01 Prof. Dr. med. Katharina Glatz Pathologie Cutaneous Adnexal Tumors Hair
More informationDISORDERS OF THE SALIVARY GLANDS Neoplasms Dr.M.Baskaran Selvapathy S IV
DISORDERS OF THE SALIVARY GLANDS Neoplasms Dr.M.Baskaran Selvapathy S IV NEOPLASMS A) Epithelial I. Benign Pleomorphic adenoma( Mixed tumour) Adenolymphoma (Warthin s tumour) Oxyphil adenoma (Oncocytoma)
More information(formalin fixed) 6 non-neoplastic spots (6 spots) Corresponding normal tissues with cancers: Yes Diameter: 1. 0 mm
CBA729-Test slide, Head and neck cancer tissues (formalin fixed) For research use only Specifications: No. of cases: 6 Tissue type: Test slide, Head and neck cancer tissues No. of spots: 6 spots from each
More information8. The polyp in the illustration can be described as (circle all that apply) a. Exophytic b. Pedunculated c. Sessile d. Frank
Quiz 1 Overview 1. Beginning with the cecum, which is the correct sequence of colon subsites? a. Cecum, ascending, splenic flexure, transverse, hepatic flexure, descending, sigmoid. b. Cecum, ascending,
More informationDifferential Diagnosis of Oral Masses. Palatal Lesions
Differential Diagnosis of Oral Masses Palatal Lesions Palatal Masses Periapical Abscess Torus Palatinus Mucocele Lymphoid Hyperplasia Adenomatous Hyperplasia Benign Salivary Neoplasms Malignant Salivary
More informationSalivary Glands 3/7/2017
Salivary Glands 3/7/2017 Goals and objectives Focus on the entities unique to H&N Common board type facts Information for your future practice Salivary Glands Salivary Glands Major gland. Paratid. Submandibular.
More informationAJCC Cancer Staging 8 th edition. Lip and Oral Cavity Oropharynx (p16 -) and Hypopharynx Larynx
AJCC Cancer Staging 8 th edition Lip and Oral Cavity Oropharynx (p16 -) and Hypopharynx Larynx AJCC 7 th edition Lip and Oral cavity Pharynx Larynx KEY CHANGES Skin of head and neck (Vermilion of the lip)
More informationCASE REPORT. Unusual spinal metastases from an adenoid cystic carcinoma of the maxillary sinus seen on a bone scan: a case report
PJNM 2016, 6:48-52 CASE REPORT 331691 2016 Pakistan Society of Nuclear Medicine Unusual spinal metastases from an adenoid cystic carcinoma of the maxillary sinus seen on a bone scan: a case report O Ait
More informationAdenoid Cystic Carcinoma Minor Salivary Gland Origin
Adenoid Cystic Carcinoma Minor Salivary Gland Origin Educational Session Presenter: Smith JA Supervisors: Palme CE, Gupta R Content Case report Imaging Primary Therapy Surgery Adjuvant Therapy Radiotherapy
More informationTemporal fossa Infratemporal fossa Pterygopalatine fossa Terminal branches of external carotid artery Pterygoid venous plexus
Outline of content Temporal fossa Infratemporal fossa Pterygopalatine fossa Terminal branches of external carotid artery Pterygoid venous plexus Boundary Content Communication Mandibular division of trigeminal
More informationParotid Gland, Temporomandibular Joint and Infratemporal Fossa
M1 - Anatomy Parotid Gland, Temporomandibular Joint and Infratemporal Fossa Jeff Dupree Sanger 9-057 jldupree@vcu.edu Parotid gland: wraps around the mandible positioned between the mandible and the sphenoid
More informationIncreased local recurrence in advanced parotid malignancy treated with mastoidectomy without lateral temporal bone resection
Oral Maxillofac Surg (2017) 21:7 11 DOI 10.1007/s10006-016-0586-x ORIGINAL ARTICLE Increased local recurrence in advanced parotid malignancy treated with mastoidectomy without lateral temporal bone resection
More informationAutonomic Nervous System. Ms. DS Pillay Room 2P24
Autonomic Nervous System Ms. DS Pillay Room 2P24 OVERVIEW OF THE NERVOUS SYSTEM NERVOUS SYSTEM CNS PNS BRAIN SPINAL CORD SOMATIC ANS SYMPATHEIC PARASYMPATHEIC LOCATION OF GANGLIA IN THE ANS Short post-ganglionic
More informationCarcinoma of Unknown Primary site (CUP) in HEAD & NECK SURGERY
Carcinoma of Unknown Primary site (CUP) in HEAD & NECK SURGERY SEARCHING FOR THE PRIMARY? P r o f J P P r e t o r i u s H e a d : C l i n i c a l U n i t C r i t i c a l C a r e U n i v e r s i t y O f
More informationCytokeratin immunoprofile of primary and metastatic adenoid cystic carcinoma of salivary glands: a report of two cases
Article / Clinical Case Report Cytokeratin immunoprofile of primary and metastatic adenoid cystic carcinoma of salivary glands: a report of two cases Cibele Pidorodeski Nagano a, Cláudia Malheiros Coutinho-Camillo
More informationInfratemporal fossa: Tikrit University college of Dentistry Dr.Ban I.S. head & neck Anatomy 2 nd y.
Infratemporal fossa: This is a space lying beneath the base of the skull between the lateral wall of the pharynx and the ramus of the mandible. It is also referred to as the parapharyngeal or lateral pharyngeal
More informationLec [8]: Mandibular nerve:
Lec [8]: Mandibular nerve: The mandibular branch from the trigeminal ganglion lies in the middle cranial fossa lateral to the cavernous sinus. With the motor root of the trigeminal nerve [motor roots lies
More informationPoor Outcomes in Head and Neck Non-Melanoma Cutaneous Carcinomas
10 The Open Otorhinolaryngology Journal, 2011, 5, 10-14 Open Access Poor Outcomes in Head and Neck Non-Melanoma Cutaneous Carcinomas Kevin C. Huoh and Steven J. Wang * Head and Neck Surgery and Oncology,
More informationTemporal region. temporal & infratemporal fossae. Zhou Hong Ying Dept. of Anatomy
Temporal region temporal & infratemporal fossae Zhou Hong Ying Dept. of Anatomy Temporal region is divided by zygomatic arch into temporal & infratemporal fossae. Temporal Fossa Infratemporal fossa Temporal
More informationNEXT STOP : Central Station "Pterygopalatine fossa"
NEXT STOP : Central Station "Pterygopalatine fossa" Poster No.: C-1359 Congress: ECR 2015 Type: Educational Exhibit Authors: I. Alba de Caceres, A. Paniagua, L. Ibañez, J. A. Blanco ; 1 1 1 1 2 2 Madrid/ES,
More informationAn Overview of Melanoma. Harriet Kluger, M.D. Associate Professor Section of Medical Oncology Yale Cancer Center
An Overview of Melanoma Harriet Kluger, M.D. Associate Professor Section of Medical Oncology Yale Cancer Center Melanoma Statistics Median age at presentation 45-55 55 years Incidence: 2003 54,200 cases
More informationNose & Mouth OUTLINE. Nose. - Nasal Cavity & Its Walls. - Paranasal Sinuses. - Neurovascular Structures. Mouth. - Oral Cavity & Its Contents
Dept. of Human Anatomy, Si Chuan University Zhou hongying eaglezhyxzy@163.com Nose & Mouth OUTLINE Nose - Nasal Cavity & Its Walls - Paranasal Sinuses - Neurovascular Structures Mouth - Oral Cavity & Its
More informationWhat is ACC? (Adenoid Cystic Carcinoma)
What is ACC? (Adenoid Cystic Carcinoma) 10-9-10 Where ACC Occurs ACC (Adenoid Cystic Carcinoma) is a rare and unique form of cancer that is known to be unpredictable in nature, with a typical growth pattern
More informationNASAL SEPTUM ADENOID CYSTIC CARCINOMA: A CASE REPORT
NASAL SEPTUM ADENOID CYSTIC CARCINOMA: A CASE REPORT Shu-Yu Tai, 1 Chen-Yu Chien, 2 Chih-Feng Tai, 2,4 Wen-Rei Kuo, 2,4 Wan-Ting Huang, 3 and Ling-Feng Wang 2,4 Departments of 1 Family Medicine, 2 Otolaryngology
More informationGreater Manchester and Cheshire HPB Unit Guidelines for the Assessment & Management of Hepatobiliary and Pancreatic Disease Chapter 14
Greater Manchester and Cheshire HPB Unit Guidelines for the Assessment & Management of Hepatobiliary and Pancreatic Disease Chapter 14 Contents 14. Neuroendocrine Tumours 161 14.1. Diagnostic algorithm
More informationCURRENT ISSUES IN TRANSPLANT DERMATOLOGY
CURRENT ISSUES IN TRANSPLANT DERMATOLOGY NO CONFLICTS OF INTEREST TO DISCLOSE SOLID ORGAN TRANSPLANTATION: 2015 As of April 10, 2015.. 123,319 patients waiting for an organ transplant 2,557 performed this
More informationNew and Emerging Therapies: Non-Melanoma Skin Cancers. David J. Goldberg, MD, JD Skin Laser and Surgery Specialists of NY/NJ
New and Emerging Therapies: Non-Melanoma Skin Cancers David J. Goldberg, MD, JD Skin Laser and Surgery Specialists of NY/NJ Disclosure Research Grant form Sensus Superficial Radiation Therapy (SRT) Modern
More informationMALIGNANT TUMOURS OF THE JAWS
MALIGNANT TUMOURS OF THE JAWS MALIGNANT TUMOURS OF THE JAWS Squamous cell carcinoma Osteogenic sarcoma Chondrosarcoma Fibrosarcoma Malignant lymphomas (incl. Burkitt s) Multiple myeloma Ameloblastoma Secondary
More informationMesothelioma: diagnostic challenges from a pathological perspective. Naseema Vorajee August 2016
Mesothelioma: diagnostic challenges from a pathological perspective Naseema Vorajee August 2016 Naseema.vorajee@nhls.ac.za Pleural diseases (whether neoplastic, reactive or infective) may have similar
More informationEDUCATIONAL CASES E1 & E2. Natasha Inglis 20/03/15
EDUCATIONAL CASES E1 & E2 Natasha Inglis 20/03/15 CASE E1 79 year old female Rectum. Altemeier operation Histology Superficial erosions and mucosal congestion volcano lesion and pseudomembrane formation
More informationMy Journey into the World of Salivary Gland Sebaceous Neoplasms
My Journey into the World of Salivary Gland Sebaceous Neoplasms Douglas R. Gnepp Warren Alpert Medical School at Brown University Rhode Island Hospital Pathology Department Providence RI Asked to present
More informationTrigeminal Nerve Worksheets, Distributions Page 1
Trigeminal Nerve Worksheet #1 Distribution by Nerve Dr. Darren Hoffmann Dental Gross Anatomy, Spring 2013 We have drawn out each of the branches of CN V in lecture and you have an idea now for their basic
More informationأملس عضلي غرن = Leiomyosarcoma. Leiomyosarcoma 1 / 5
Leiomyosarcoma 1 / 5 EPIDEMIOLOGY Exact incidence is unknown, but older studies suggest that leiomyosarcomas comprise approximately 3 percent of soft-tissue sarcomas. Superficial leiomyosarcoma occurs
More information! BIOL 2401! Week 5. Nervous System. Nervous System
Collin County Community College! BIOL 2401! Week 5 Nervous System 1 Nervous System The process of homeostasis makes sure that the activities that occur in the body are maintained within normal physiological
More informationUSCAP 2012: Companion Meeting of the AAOOP. Update on lacrimal gland neoplasms: Molecular pathology of interest
USCAP 2012: Companion Meeting of the AAOOP Vancouver BC, Canada, March 17, 2012 Update on lacrimal gland neoplasms: Molecular pathology of interest Valerie A. White MD, MHSc, FRCPC Department of Pathology
More informationAJCC Staging of Head & Neck Cancer (7 th edition, 2010) -LIP & ORAL CAVITY-
TX: primary tumor cannot be assessed T0: no evidence of primary tumor Tis: carcinoma in situ. T1: tumor is 2 cm or smaller AJCC Staging of Head & Neck Cancer (7 th edition, 2010) -LIP & ORAL CAVITY- T2:
More informationThere are 3 pairs of major salivary glands, namely
Kathmandu University Medical Journal (2008), Vol. 6, No. 2, Issue 22, 204-208 Original Article Role of FNAC in the diagnosis of salivary gland swellings Akhter J 1, Hirachand S 1, Lakhey M 2 1 Lecturer,
More informationOral Cancer Risk and Detection
Oral Cancer Risk and Detection Evan M. Graboyes, MD Assistant Professor Department of Otolaryngology-Head & Neck Surgery Cancer Control Program, Hollings Cancer Center Medical University of South Carolina
More informationComputed Tomography Evaluation of Oral Cavity and Oropharyngeal Cancers
AIJOC 10.5005/jp-journals-10003-1111 REVIEW ARTICLE Computed Tomography Evaluation of Oral Cavity and Oropharyngeal Cancers Computed Tomography Evaluation of Oral Cavity and Oropharyngeal Cancers Sunita
More informationTumours of the Oesophagus & Gastro-Oesophageal Junction Histopathology Reporting Proforma
Tumours of the Oesophagus & Gastro-Oesophageal Junction Histopathology Reporting Proforma Mandatory questions (i.e. protocol standards) are in bold (e.g. S1.01). S1.01 Identification Family name Given
More informationTechnicians & Nurses Program
ASCRS ASOA Symposium & Congress Technicians & Nurses Program May 6-10, 2016 New Orleans Evaluation and Treatment of Eyelid Malignancies Richard C. Allen MD PhD FACS Professor Section of Ophthalmology Dept.
More information2401 : Anatomy/Physiology
Dr. Chris Doumen Week 5 2401 : Anatomy/Physiology Introduction Neural Tissue TextBook Readings Pages 388 through 397. Make use of the figures in your textbook ; a picture is worth a thousand words! Work
More informationCT findings of osteoradionecrosis of the mandible
CT findings of osteoradionecrosis of the mandible Poster No.: C-2569 Congress: ECR 2015 Type: Educational Exhibit Authors: J. Abreu e Silva, M. J. Magalhães, N. Costa, S. Ramos Alves, M. V. P. P. Gouvea;
More informationHead and Neck Squamous Subtypes
1 Head and Neck Squamous Subtypes Adel K. El-Naggar, M.D., Ph.D. The University of Texas MD Anderson Cancer Center, Houston, Texas HNSCC 5 th -6 th most common cancer 400,000/year 50% mortality Considerable
More informationCase Report Surgical Procedures for External Auditory Canal Carcinoma and the Preservation of Postoperative Hearing
Volume 2012, Article ID 841372, 4 pages doi:10.1155/2012/841372 Case Report Surgical Procedures for External Auditory Canal Carcinoma and the Preservation of Postoperative Hearing Hiroshi Hoshikawa, Takenori
More informationInteresting Case Series. Desmoplastic Melanoma
Interesting Case Series Desmoplastic Melanoma Anthony Maurice Kordahi, MD, Joshua B. Elston, MD, Ellen M. Robertson, MD, and C. Wayne Cruse, MD Division of Plastic Surgery, Department of Surgery, University
More informationNo IN THE SUPREME COURT OF ALABAMA
E-Filed 09/22/2017 @ 03:05:41 PM Honorable Julia Jordan Weller Clerk Of The Court No. 1881555 IN THE SUPREME COURT OF ALABAMA Ex parte Doyle Lee Hamm, * * In re. State of Alabama * Petitioner, * Fourth
More informationThymic Tumors. Feiran Lou MD. MS. Kings County Hospital Department of Surgery
Thymic Tumors Feiran Lou MD. MS. Kings County Hospital Department of Surgery Case HPI 53 yo man referred from OSH for anterior mediastinal mass. Initially presented with leg weakness and back pain for
More informationAdenoid cystic carcinoma of the head and neck
British Journal of Plastic Surgery (2001), 54, 476--480 9 2001 The British Association of Plastic Surgeons doi: 10.1054/bjps.2001.3636 PLASTC SURGERY Adenoid cystic carcinoma of the head and neck S. Chummun,
More informationRadiation Technology, Hyogo Ion Beam Medical Center, Tatsuno, Hyogo, JAPAN
Analysis of Visual Loss Due to Radiation- Induced Optic Neuropathy After Particle Therapy for Head and Neck and Skull Base Tumors Adjacent to Optic Nerves Y. Demizu 1, M. Murakami 1, D. Miyawaki 1, Y.
More informationProtons for Head and Neck Cancer. William M Mendenhall, M.D.
Protons for Head and Neck Cancer William M Mendenhall, M.D. Protons for Head and Neck Cancer Potential Advantages: Reduce late complications via more conformal dose distributions Likely to be the major
More informationNeurotropic cutaneous malignant melanoma with contiguous spread to spinal cord, an extremely rare presentation
Case Report Neurotropic cutaneous malignant melanoma with contiguous spread to spinal cord, an extremely rare presentation Sheikh Asad, Idrees Sher, Jens Peters-Willke, Peter Jessup Departments of Neurosurgery
More informationIntroduction to Local Anesthesia and Review of Anatomy
5-Sep Introduction and Anatomy Review 12-Sep Neurophysiology and Pain 19-Sep Physiology and Pharmacology part 1 26-Sep Physiology and Pharmacology part 2 Introduction to Local Anesthesia and Review of
More informationRadio-Pathologic Workup of a Retroperitoneal Abdominal Mass
Radio-Pathologic Workup of a Retroperitoneal Abdominal Mass Joe Carlson Advanced Radiology Clerkship Harvard Medical School Year IV September 12, 2002 84 year old Male Presented to PCP With Abdominal Pain
More informationUNUSUALLY DELAYED RECURRENCE OF A LOW GRADE MUCOEPIDERMOID CARCINOMA OF THE MAXILLARY SINUS
Official Publication of OrofacialChronicle, India www.jhnps.weebly.com CASE REPORT UNUSUALLY DELAYED RECURRENCE OF A LOW GRADE MUCOEPIDERMOID CARCINOMA OF THE MAXILLARY SINUS ABSTRACT: Nitish Virmani 1,
More informationHistopathological Study of Lacrimal Gland Tumors
ORIGINAL ARTICLE Pratikkumar B. Desai 1, Ami Shah 2 1 4 th Year Resident, Pathology Department, B.J.Medical College, Civil Hospital, Ahmedabad 2 Associate Professor, M. J. Institute of Ophthalmology, Civil
More informationAJCC update Disclosures. AJCC TNM staging system. Objectives:
Disclosures AJCC update 2018 Remy Lobo, MD remylobo@med.umich.edu remy.lobo@hsc.utah.edu No relevant disclosures Information is based on the 8 th AJCC manual Amin MB, Edge SB, Greene FL et al, eds. AJCC
More informationOutline. Neuroradiology. Diffusion Imaging in. Clinical Applications of. Basics of Diffusion Imaging. Basics of Diffusion Imaging
Clinical Applications of Diffusion Imaging in Neuroradiology No disclosures Stephen F. Kralik Assistant Professor of Radiology Indiana University School of Medicine Department of Radiology and Imaging
More informationLya Crichlow, MD Lutheran Medical Center November 21, 2008
Lya Crichlow, MD Lutheran Medical Center November 21, 2008 Case Presentation 64 year old male presented with a painless mass posterior to the right angle of the mandible for 3 months PMHx HTN COPD BPH
More informationPancreatobiliary Frozen Section Nightmares
Pancreatobiliary Frozen Section Nightmares Aatur D. Singhi, MD PhD Assistant Professor University of Pittsburgh Medical Center Department of Pathology singhiad@upmc.edu Objectives Briefly give an overview
More informationSee the latest estimates for new cases of salivary gland cancers in the US and what research is currently being done.
About Salivary Gland Cancer Overview and Types If you have been diagnosed with salivary gland cancer or are worried about it, you likely have a lot of questions. Learning some basics is a good place to
More informationModalities of Radiation
Modalities of Radiation Superficial radiotherapy Orthovoltage Megavoltage Photons Electrons Brachytherapy Interstitial Moulds When to refer? The vast majority of skin cancers will be managed without any
More informationUPDATE ON RADIOTHERAPY
1 Miriam Kleiter UPDATE ON RADIOTHERAPY Department for Companion Animals and Horses, Plattform Radiooncology and Nuclear Medicine, University of Veterinary Medicine Vienna Introduction Radiotherapy has
More informationTrigeminal Nerve (V)
Trigeminal Nerve (V) Lecture Objectives Discuss briefly how the face is developed. Follow up the course of trigeminal nerve from its point of central connections, exit and down to its target areas. Describe
More informationJuvenile Angiofibroma
Juvenile Angiofibroma Disclaimer The pictures used in this presentation have been obtained from a number of sources. Their use is purely for academic and teaching purposes. The contents of this presentation
More information