新型 DES 和 BVS 血栓发生现状及应对策略 钱菊英,MD, FACC,FESC 复旦大学附属中山医院上海市心血管病研究所

Size: px
Start display at page:

Download "新型 DES 和 BVS 血栓发生现状及应对策略 钱菊英,MD, FACC,FESC 复旦大学附属中山医院上海市心血管病研究所"

Transcription

1 新型 DES 和 BVS 血栓发生现状及应对策略 钱菊英,MD, FACC,FESC 复旦大学附属中山医院上海市心血管病研究所 OCC2016

2 Increase of LST and death for first generation DES after stop of 6m DAPT

3 BASKET-LATE Study P< m FU Pfisterer M, et al. J Am Coll Cardiol. 2006;48(12):

4 Current ST status of 1st DES Outcomes associated with drug-eluting and baremetal stents: a collaborative network meta-analysis 27 trials provide data on definite stent thrombosis according to ARC criteria. 1-4 years FU Stettler C, et al. Lancet. 2007;370:

5 TAXUS CYPHER BMS Stettler C, et al. Lancet. 2007;370:

6 Current ST status of new generation of DES TAXUS ENDEAVOR XIENCE CYPHER Stent thrombosis with drug-eluting and bare-metal stents: evidence from a comprehensive network meta-analysis RESOLUTE PROMUS ELEMENT Palmerini T, et al. Lancet. 2012;379:

7 1-year definite ST was significantly lower with CoCr-EES than with BMS and PES, even lower than with Resolute. At 2-year follow-up, CoCr-EES were still associated with significantly lower rates of definite ST than BMS and PES. No other DES had lower definite ST rates compared with BMS at 2-year follow-up. Palmerini T, et al. Lancet. 2012;379:

8 Current ST status of BVS Acute ST 0.27% Subacute ST 0.57% late Very Late acute This may reflect an increase in the studies using BVS in patients with ACS. Lipinski M, et al. JACC Cardiovasc Interv. 2016;9: Puricel S, et al. J Am Coll Cardiol. 2016;67:

9 Lipinski M, et al. JACC Cardiovasc Interv. 2016;9:12-24.

10 Cause of DES ST Compliance With Antithrombotic Regimens at the Time of Stent Thrombosis Waksman R, et al. JACC Cardiovasc Interv. 2014;7(10): Holmes DR Jr, et al. J Am Coll Cardiol. 2010;56(17): Urban P, et al. J Am Coll Cardiol. 2011;57:

11 OCT analysis of ST dissection malapposition Uncovered struts neoatherosclerosis Ruptured neoatherosclerosis Ruptured neoatherosclerosis Souteyrand G, et al. Eur Heart J. 2016;37(15):

12 Cause of BVS ST Similar to DES, ST is a particularly severe complication whose 12- month incidence was as high as 3%. None of the clinical characteristics was an independent predictor of ST. QCA features of small vessels were a hallmark of ST. Suboptimal post-procedural angiographic results, with even small deviations from the nominal BVS diameter, were associated with exponential increases in the risk of ST. The curve describing the positive predictive values of different post-procedural MLDs showed a steeper increase for values <2.4/2.8 mm. MLD values <2.1 mm (for the 2.5-/3.0-mm BVS) and 2.7 mm (for the 3.5-mm BVS) were associated with ST with a specificity of 90% and a sensitivity of 50%. Puricel S, et al. J Am Coll Cardiol. 2016;67:

13 ST risk assessment and prevention Patient, lesion, and stent selection Risk score calculation Technique DAPT compliance and interruption Claessen BE, et al. JACC Cardiovasc Interv. 2014;7(10):

14 Patient, lesion, and stent selection BMS lesion with low risk of restenosis and patients at increased risk of bleeding, scheduled for surgery, allergic to thienopyridines, and/or in whom compliance is questionable. New generation of DES (XIENCE, RESOLUTE, and PROMUS ELEMENT) provide the best combination of safety and efficacy. Fully bioabsorbable scaffold may reduce very late stent thrombosis, but long-term results of large-scale trials investigating the safety and efficacy are not yet available.

15 Risk score calculation Dangas GD, et al. JACC Cardiovasc Interv. 2012;5:

16 Low risk of ST intermediate High risk of ST Dangas GD, et al. JACC Cardiovasc Interv. 2012;5:

17 Technique Optimize the results of procedure Proper stent expansion and apposition Avoid residual dissection IVUS guided stent implantation Stent length, excessive use of stents is discouraged Provisional side-branch stenting approach might be preferable to routine CRUSH or CULOTTE stenting in bifurcation lesion

18 DAPT Recommendation Binder RK, et al. Eur Heart J. 2015;36(20):

19 MACCE and DAPT duration Low bleeding risk 6 months 12 months 30 months Intermediate Favor long DAPT OPTIMIZE RESET EXCELLENT PRODIGY ITALIC DES LATE DAPT OPTIMIZE RESET EXCELLENT PRODIGY ITALIC DES LATE DAPT Short DAPT Individualized DAPT management Low ischemic risk Long DAPT P< Bleeding and DAPT duration Intermediate 2.9 ischemic risk 2.3 Short DAPT = 3-12m Long DAPT = 12-36m Short DAPT High ischemic risk P=0.004 bleeding risk 3-6 months 6-12 months 12 months Long DAPT High bleeding risk 3 months 3-6 months 6-12 months P= Binder RK, et al. Eur Heart J. 2015;36(20): Palmerini T, Lancet. 2015;385(9985):

20 A DAPT score is recommended. A score of 2 is associated with a favorable benefit/risk ratio for prolonged DAPT while a score of <2 is associated with an unfavorable benefit/risk ratio.

21 2016 新指南对双抗疗程管理的推荐 : 依据疾病类型 再灌注方法和缺血及出血风险 CAD SIHD 急性 / 近期 ACS (NSTE-ACS 或 STEMI) 无 PCI 史或近期 CABG S/P PCI S/P CABG 药物治疗 溶栓 (STEMI) PCI (BMS 或 DES) CABG BMS DES 0 个月 6 个月 12 个月 III 类 : 无获益 I 类 : 至少 1 个月 ( 氯吡格雷 ) I 类 : 至少 6 个月 ( 氯吡格雷 ) 无出血高风险及明显出血 IIb 类 : >1 个月是合理的 IIb 类 : >6 个月是合理的 IIb 类 : 12 个月是合理的 ( 氯吡格雷 ) I 类 : 至少 12 个月 ( 氯吡格雷 替格瑞洛 ) I 类 : 最少 14 天, 理想情况下为至少 12 个月 ( 氯吡格雷 ) I 类 : 至少 12 个月 ( 氯吡格雷 普拉格雷 替格瑞洛 ) I 类 : CABG 术后继续接受 P2Y12 抑制剂治疗, 以完成 1 年 DAPT 无出血高风险及明显出血 IIb 类 :>12 个月是合理的 图底部的箭头表示延长 DAPT 的最佳疗程并不确定 Levine GN, et al. J Am Coll Cardiol Mar 23. pii: S (16)

22 Take home messages ST of new generation of DES is lower than 1 st DES, even lower than BMS. BVS may reduce very late ST, but long-term results are not yet available. Carefully selection of patient, lesion and stent may reduce the occurrence of ST. Optimize the results of PCI. Individualized DAPT is recommended.

23 Thank You!

生物可吸收支架和聚合物涂层可降解 支架能消除支架内血栓吗? 钱菊英,MD, FACC,FESC 复旦大学附属中山医院上海市心血管病研究所

生物可吸收支架和聚合物涂层可降解 支架能消除支架内血栓吗? 钱菊英,MD, FACC,FESC 复旦大学附属中山医院上海市心血管病研究所 生物可吸收支架和聚合物涂层可降解 支架能消除支架内血栓吗? 钱菊英,MD, FACC,FESC 复旦大学附属中山医院上海市心血管病研究所 PCI milestones Pre Post Biodegradable polymer? 1 st revolution 1977 PTCA 2 nd revolution 1988 BMS 3 rd revolution 2000 DES Bioresorbable

More information

Definition of Stroke ( 中风 )

Definition of Stroke ( 中风 ) Definition of Stroke ( 中风 ) Sudden brain damage Lack of blood flow to the brain caused by a clot or rupture of a blood vessel Ischemia = Clot 缺血 (makes up approximately 87% of all strokes) Embolic Thrombotic

More information

Komplexe Koronarintervention heute: Von Syntax zu bioresorbierbaren Stents

Komplexe Koronarintervention heute: Von Syntax zu bioresorbierbaren Stents Komplexe Koronarintervention heute: Von Syntax zu bioresorbierbaren Stents Prof. Dr. med. Julinda Mehilli Medizinische Klinik und Poliklinik I Klinikum der Universität München Campus Großhadern Key Factors

More information

Małgorzata Golik. Physiotherapist, certified, master s degree physiotherapist, neurological disorders specialist

Małgorzata Golik. Physiotherapist, certified, master s degree physiotherapist, neurological disorders specialist 全身运动反馈系统在波兰和欧洲的应用 Małgorzata Golik Physiotherapist, certified, master s degree physiotherapist, neurological disorders specialist Graduation: Warsaw Academy of Physical Activity and Education, Poland Poland

More information

宫颈上皮内瘤变 ; IgG1 IgG2 亚类 ; 酶联免疫吸附试验 R A (2009)

宫颈上皮内瘤变 ; IgG1 IgG2 亚类 ; 酶联免疫吸附试验 R A (2009) 2009 年第 19 卷第 11 期 CHINA ONCOLOGY 2009 Vol.19 No.11 831 免疫球蛋白 G(immunoglobulin G,IgG) 是血清和细胞外液中含量最高的免疫球蛋白, 其某个亚类的升高, 可能与宫颈上皮内瘤变 (cervical intraepithelial neoplasia, CIN) 的发生 发展及转归有密切相关 然而对于 CIN 患者血清人乳头瘤病毒样颗粒

More information

读书报告 2015 年 月 唐之韵

读书报告 2015 年 月 唐之韵 读书报告 2015 年 03-04 月 唐之韵 Mar. Apr. NEJM VOL.372 Kaukonen KM1, Bailey M, Pilcher D, et al. N Engl J Med. 2015 Apr 23;372(17):1629-38. Systemic Inflammatory Response Syndrome Criteria in Defining Severe Sepsis.

More information

Development of clinical trial for molecular targeted therapy in Breast Cancer

Development of clinical trial for molecular targeted therapy in Breast Cancer Development of clinical trial for molecular targeted therapy in Breast Cancer Ze-Fei Jiang 军事医学科学院附属医院 江泽飞 Cancer Drug Development: 1945 Present Total No. Approved Drugs 85 75 65 55 Ibritumomab/Tositumomab/Bortezomib

More information

结构性心脏病介入治疗进展 周达新 复旦大学附属中山医院上海市心血管病研究所. Approaches to structural Heart Disease of Intervention

结构性心脏病介入治疗进展 周达新 复旦大学附属中山医院上海市心血管病研究所. Approaches to structural Heart Disease of Intervention 结构性心脏病介入治疗进展 Approaches to structural Heart Disease of Intervention 周达新 复旦大学附属中山医院上海市心血管病研究所 Interventional Cath for CHD In 1967 Porstmann helped develop the Ivalon plug and was the first to use it clinically.

More information

What s New in Antiplatelet Therapy and DES in 2016

What s New in Antiplatelet Therapy and DES in 2016 What s New in Antiplatelet Therapy and DES in 2016 Peter Pollak MD Director of Structural Heart Disease & Intervention Mayo Clinic Florida 2016 slide-1 Disclosures Financial None Off-label - None 2016

More information

Hypertension and cardiac arrhythmias

Hypertension and cardiac arrhythmias CardioPulse 223 doi:10.1093/eurheartj/ehw664 Hypertension and cardiac arrhythmias A consensus document from the European Heart Rhythm Association (EHRA) and European Society of Cardiology (ESC) Council

More information

Received Accepted This work was supported by the National Natural Science Foundation of China (No ).

Received Accepted This work was supported by the National Natural Science Foundation of China (No ). Acta Physiologica Sinica, August 25, 2012, 64(4): 449 454 http://www.actaps.com.cn 449 Research Paper Involvement of protein kinase A activation and phospholipase A 2 inhibition in the adenosine-activated

More information

How to Make the Choice?

How to Make the Choice? How to Make the Choice? Translational Approach for Cancer Treatment 闻丹忆 Danyi.wen@lidebiotech.com 181 9229 52 Nov 23, 214 1 Tumor volume (mm 3 ) Tumor growth (Efficacy study in LIX4-FP1+2) 15 Vehiclel,

More information

TLR des Stents Actifs

TLR des Stents Actifs TLR des Stents Actifs No Conflict of Interest Target Lesion Revascularization DES vs BMS Stettler C et al. Lancet 2007;370:937-48 N=18,023 58% 70% SES vs BMS: HR=0.30 (0.24-0.37), p

More information

Drug Eluting Stents Sometimes Fail ESC Stockholm 29 Set 2010 Stent Thrombosis Alaide Chieffo

Drug Eluting Stents Sometimes Fail ESC Stockholm 29 Set 2010 Stent Thrombosis Alaide Chieffo Drug Eluting Stents Sometimes Fail ESC Stockholm 29 Set 2010 Stent Thrombosis 11.45-12.07 Alaide Chieffo San Raffaele Scientific Institute, Milan, Italy Historical Perspective 25 20 15 10 5 0 Serruys 1991

More information

500 中国肺癌杂志2010年5月第13卷第5期 C h i n J L u n g C a n c e r, M ay , Vo l. 1 3, No. 5 临床研究 血清TPS CEA Pro-GRP和CYFRA21-1 水平在肺癌患者中的临床意义 王敬慧 时广利 张树才 王群慧

500 中国肺癌杂志2010年5月第13卷第5期 C h i n J L u n g C a n c e r, M ay , Vo l. 1 3, No. 5 临床研究 血清TPS CEA Pro-GRP和CYFRA21-1 水平在肺癌患者中的临床意义 王敬慧 时广利 张树才 王群慧 5 临床研究 血清 和CYFRA- 水平在肺癌患者中的临床意义 王敬慧 时广利 张树才 王群慧 杨新杰 李曦 王海永 张卉 宋长兴 摘要 背景与目的 血清肿瘤标志物在肺癌的诊断 疗效 预后判断中起着重要作用 本研究探讨血清组 织多肽特异性抗原 tissue polypeptide specific antigen, 与癌胚抗原 carcinoembryonic antigen, 胃泌素释放 肽前体

More information

Béla MERKELY MD, PhD, DSc, FESC. Stent thrombosis: patophysiology, predisposing factors, definition, classification, prevention and treatment

Béla MERKELY MD, PhD, DSc, FESC. Stent thrombosis: patophysiology, predisposing factors, definition, classification, prevention and treatment Semmelweis University Heart Center Budapest, Hungary Béla MERKELY MD, PhD, DSc, FESC Stent thrombosis: patophysiology, predisposing factors, definition, classification, prevention and treatment 10th Interventional

More information

Coronary Stent Choice in Patients With Diabetes Mellitus

Coronary Stent Choice in Patients With Diabetes Mellitus Rome Cardiology Forum 2014 Coronary Stent Choice in Patients With Diabetes Mellitus Stephan Windecker Department of Cardiology Swiss Cardiovascular Center and Clinical Trials Unit Bern Bern University

More information

中国 HIV 新发感染检测发展及未来 Development and Future of HIV-1 Incidence Assay in China

中国 HIV 新发感染检测发展及未来 Development and Future of HIV-1 Incidence Assay in China 中国 HIV 新发感染检测发展及未来 Development and Future of HIV-1 Incidence Assay in China Yan Jiang MD, PhD. National HIV Reference Laboratory, China CDC 中国 HIV 检测体系 HIV Testing in China Screening Confirmatory Recent

More information

How to Predict & Prevent It! George D. Dangas, MD, FACC, FESC

How to Predict & Prevent It! George D. Dangas, MD, FACC, FESC Stent Thrombosis How to Predict & Prevent It! George D. Dangas, MD, FACC, FESC Professor of Cardiology & Vascular Surgery Icahn School of Medicine at Mount Sinai New York, NY Καθηγητής Καρδιολογίας ΕΚΠΑ

More information

DAPT in CAD, Acute & Chronic CAD, antiplatelet therapy non-responders

DAPT in CAD, Acute & Chronic CAD, antiplatelet therapy non-responders DAPT in CAD, Acute & Chronic CAD, antiplatelet therapy non-responders Annual Ohio ACC Conference October 14, 2017 Ernest L. Mazzaferri Jr, MD, FACC, FSCAI Disclosures No financial disclosures related to

More information

Safety of Drug-Eluting Stents in Acute Coronary Syndromes

Safety of Drug-Eluting Stents in Acute Coronary Syndromes Rotterdam, June 11 th 2012 Safety of Drug-Eluting Stents in Acute Coronary Syndromes Stephan Windecker Department of Cardiology Swiss Cardiovascular Center and Clinical Trials Unit Bern Bern University

More information

A Case Report on Primary Ovarian Leiomyo-Sarcoma and Some Related Documents Review

A Case Report on Primary Ovarian Leiomyo-Sarcoma and Some Related Documents Review Asian Case Reports in Oncology 亚洲肿瘤科病例研究, 2013, 2, 11-15 http://dx.doi.org/10.12677/acrpo.2013.23004 Published Online July 2013 (http://www.hanspub.org/journal/acrpo.html) A Case Report on Primary Ovarian

More information

Affiliation/Financial Relationship

Affiliation/Financial Relationship The Next ERA: COMBO Dual Therapy Stent The Unmet Need Roxana Mehran, MD Mount Sinai i School of Medicine i Disclosure Statement of Financial Interest Within the past 12 months, I or my spouse/partner have

More information

Disclosures. Theodore A. Bass MD, FSCAI. The following relationships exist related to this presentation. None

Disclosures. Theodore A. Bass MD, FSCAI. The following relationships exist related to this presentation. None SCAI Fellows Course December 10, 2013 Disclosures Theodore A. Bass MD, FSCAI The following relationships exist related to this presentation None Current Controversies on DAPT in PCI Which drug? When to

More information

老年与中青年急性呼吸窘迫综合征患者的特点及预后相关危险因素分析

老年与中青年急性呼吸窘迫综合征患者的特点及预后相关危险因素分析 794 中华危重病急救医学 2014 年 11 月第 26 卷第 11 期 Chin Crit Care Med,November 2014,Vol.26,No.11 论著 老年与中青年急性呼吸窘迫综合征患者的特点及预后相关危险因素分析 摘要 目的比较重症监护病房 (ICU) 内老年及中青年急性呼吸窘迫综合征 (ARDS) 患者的临床特点及预后相关危险因素 方法回顾性分析 2011 年 8 月至 2013

More information

Health: Acupuncture in the UK 健康 : 针灸在英国

Health: Acupuncture in the UK 健康 : 针灸在英国 Health: Acupuncture in the UK 健康 : 针灸在英国 1 Health: Acupuncture in the UK 健康 : 针灸在英国 A Better Way to Beat Back Pain? 腰疼有救吗? What is the single largest cause of sick leave in the UK? The answer is not the

More information

Innovation in Cardiovascular Interventions. New DES, Scaffolds and other Devices Have Angioplasty Results Improved

Innovation in Cardiovascular Interventions. New DES, Scaffolds and other Devices Have Angioplasty Results Improved Innovation in Cardiovascular Interventions New DES, Scaffolds and other Devices Have Angioplasty Results Improved Alexandra Lansky, MD Yale University School of Medicine University College of London DES

More information

The BIO revolution: bioadsorbable stents. Federico Conrotto Cardiologia 2 Città della Salute e della Scienza di Torino

The BIO revolution: bioadsorbable stents. Federico Conrotto Cardiologia 2 Città della Salute e della Scienza di Torino The BIO revolution: bioadsorbable stents Federico Conrotto Cardiologia 2 Città della Salute e della Scienza di Torino BVS stent (Abbot Vascular) Strut Material: Poly-L-Lactic acid Coating Material: Poly-D,L-lactide

More information

Balancing Efficacy and Safety of P2Y12 Inhibitors for ACS Patients

Balancing Efficacy and Safety of P2Y12 Inhibitors for ACS Patients SYP.CLO-A.16.07.01 Balancing Efficacy and Safety of P2Y12 Inhibitors for ACS Patients dr. Hariadi Hariawan, Sp.PD, Sp.JP (K) TOPICS Efficacy Safety Consideration from Currently Available Antiplatelet Agents

More information

Stents selection and optimal implantation: sizes, design, deployment Abbott Vascular. All rights reserved.

Stents selection and optimal implantation: sizes, design, deployment Abbott Vascular. All rights reserved. Stents selection and optimal implantation: sizes, design, deployment Stent classification: Mechanism of expansion - Self-expanding - Balloon expandable Design - Mesh structure - Coil - Slotted tube - Ring

More information

What Stent to Use? JASVINDAR SINGH MD, FACC

What Stent to Use? JASVINDAR SINGH MD, FACC What Stent to Use? JASVINDAR SINGH MD, FACC ASSOCIATE PROFESSOR OF MEDICINE WASHINGTON UNIVERSITY IN ST. LOUIS DIRECTOR, CARDIAC CATHETERIZATION LAB BARNES-JEWISH HOSPITAL What Stent to Use? Jasvindar

More information

Stephen G. Ellis, M.D. Professor of Medicine Director Invasive Services Co-Director Cardiac Gene Bank

Stephen G. Ellis, M.D. Professor of Medicine Director Invasive Services Co-Director Cardiac Gene Bank From ABSORB Cohort A to ABSORB III and IV Randomized Trials Stephen G. Ellis, M.D. Professor of Medicine Director Invasive Services Co-Director Cardiac Gene Bank Disclosures Consultant, Abbott Vascular

More information

INSIDE INFORMATION YOU CAN T IGNORE

INSIDE INFORMATION YOU CAN T IGNORE INSIDE INFORMATION YOU CAN T IGNORE Volcano, the Volcano logo and SyncVision are registered trademarks of Volcano Corporation. All other trademarks set-forth are properties of their respective owners.

More information

EGFR-TKI 治疗肺癌耐药的对 策和困境 上海市肺科医院肿瘤科 周彩存

EGFR-TKI 治疗肺癌耐药的对 策和困境 上海市肺科医院肿瘤科 周彩存 EGFR-TKI 治疗肺癌耐药的对 策和困境 上海市肺科医院肿瘤科 周彩存 Chemotherapy for advanced NSCLC 0 25 50 75 100 MST (M) ORR (%) SWOG 9509 (N=410) PCAR VCIS 8.0 8.0 25 28 PCIS 8.1 21 ECOG 1594 (N=1163) GCIS DCIS 8.1 7.4 17 21 PCAR

More information

New Generation Drug- Eluting Stent in Korea

New Generation Drug- Eluting Stent in Korea New Generation Drug- Eluting Stent in Korea Young-Hak Kim, MD, PhD Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Purpose To briefly introduce the

More information

Add Your Company Slogan 损伤的修复. Repair of the injury 白求恩医学院病理教研室 Logo

Add Your Company Slogan 损伤的修复. Repair of the injury 白求恩医学院病理教研室 Logo Add Your Company Slogan 损伤的修复 白求恩医学院病理教研室 李 伟 2010.9.26 tissue and cellular injury Normal cells Adaptation irreversible injury reversible injury Adaptation hypertrophy hyperplasia atrophy metaplasia cellular

More information

Tree shrew models: A chronic social defeat model of depression and a one-trial captive conditioning model of learning and memory

Tree shrew models: A chronic social defeat model of depression and a one-trial captive conditioning model of learning and memory 动物学研究 2011,Feb. 32(1): 24 30 CN 53-1040/Q ISSN 0254-5853 Zoological Research DOI:10.3724/SP.J.1141.2011.01024 Tree shrew models: A chronic social defeat model of depression and a one-trial captive conditioning

More information

病毒基因组学与 病毒进化 刘翟博士研究员 中国科学院微生物研究所

病毒基因组学与 病毒进化 刘翟博士研究员 中国科学院微生物研究所 病毒基因组学与 病毒进化 刘翟博士研究员 中国科学院微生物研究所 2016-6-27 新一代测序技术带来了测序成本的大大降低!!! $100,000,000 $10,000,000 Moore s Law $1,000,000 $100,000 $10,000 $1,000 $1,000 $100 Pathogens Genomics Pathogen infections are among the

More information

Cross-sectional study on the relationship between life events and mental health of secondary school students in Shanghai, China

Cross-sectional study on the relationship between life events and mental health of secondary school students in Shanghai, China 162 Shanghai Archives of Psychiatry, 2012, Vol.24, No.3 Cross-sectional study on the relationship between life events and mental health of secondary school students in Shanghai, China Linlin ZHOU, Juan

More information

IVUS Assessment of the Mechanism of In-stent Restenosis? Gary S. Mintz, MD Cardiovascular Research Foundation

IVUS Assessment of the Mechanism of In-stent Restenosis? Gary S. Mintz, MD Cardiovascular Research Foundation IVUS Assessment of the Mechanism of In-stent Restenosis? Gary S. Mintz, MD Cardiovascular Research Foundation SURE Trial: Restenosis in non-stented lesions Average of the two image slices with the smallest

More information

DNA-EGS1386 in cells induced RNase P inhibits the expression of human cytomegalovirus UL49 gene

DNA-EGS1386 in cells induced RNase P inhibits the expression of human cytomegalovirus UL49 gene 生物工程学报 Chin J Biotech 2009, November 25; 25(11): 1690-1696 journals.im.ac.cn Chinese Journal of Biotechnology ISSN 1000-3061 cjb@im.ac.cn 2009 Institute of Microbiology, CAS & CSM, All rights reserved

More information

Introduction CME. KY Lo *, CK Chan

Introduction CME. KY Lo *, CK Chan CME Original Article Characteristics and outcomes of patients with percutaneous coronary intervention for unprotected left main coronary artery disease: a Hong Kong experience KY Lo *, CK Chan This article

More information

DECLARATION OF CONFLICT OF INTEREST

DECLARATION OF CONFLICT OF INTEREST DECLARATION OF CONFLICT OF INTEREST In the last five years, I received research grants or speaker fees or I am/was consultant for: Abbott Vascular, Asahi, Astra Zeneca, AVI, Boston Scientific, Biotronik,

More information

Bioresorbable Stents: Innovation or Bust?

Bioresorbable Stents: Innovation or Bust? Bioresorbable Stents: Innovation or Bust? Rajiv Jauhar, MD FACC, FSCAI Chief of Cardiology Director of Cardiac Cath Labs Northshore University Hospital San Diego July, 2016 Conflict of Interest Disclosure

More information

Αγγειοπλαστική σε Eπαναστενωτικές Bλάβες

Αγγειοπλαστική σε Eπαναστενωτικές Bλάβες Αγγειοπλαστική σε Eπαναστενωτικές Bλάβες Βάιος Π. Τζίφος Δ/ντής Γ Καρδιολογικής Κλινικής - Επεμβατικής Καρδιολογίας. Ερρίκος Ντυνάν HC The Mehran s Classification for BMS-ISR Prognostic Value Pattern (1)

More information

南京, 第十二届分子标志与核医学靶向诊断治疗大会, 心血管分子显像的进展 何作祥 国家心血管病中心国家心血管疾病临床医学研究中心心血管疾病国家重点实验室中国医学科学院阜外心血管病医院

南京, 第十二届分子标志与核医学靶向诊断治疗大会, 心血管分子显像的进展 何作祥 国家心血管病中心国家心血管疾病临床医学研究中心心血管疾病国家重点实验室中国医学科学院阜外心血管病医院 南京, 第十二届分子标志与核医学靶向诊断治疗大会,2017.9.9 心血管分子显像的进展 何作祥 国家心血管病中心国家心血管疾病临床医学研究中心心血管疾病国家重点实验室中国医学科学院阜外心血管病医院 Molecular Imaging in Cardiovascular Diseases Evaluation of myocardial viability and ischemic memory Imaging

More information

Concurrent pulmonary thrombosis with systemic embolism: a case report *

Concurrent pulmonary thrombosis with systemic embolism: a case report * 838 Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology) ISSN 1673-1581 (Print); ISSN 1862-1783 (Online) www.zju.edu.cn/jzus; www.springerlink.com E-mail: jzus@zju.edu.cn Case Report:

More information

malapposition assessed by OCT

malapposition assessed by OCT Stent t coverage and malapposition assessed by OCT Myeong-Ki Hong, M.D. Ph D Professor of Medicine Division of Cardiology, Severance Cardiovascular Hospital Yonsei University College of Medicine, Seoul,

More information

HCS Working Group Seminars Macedonia Pallas Hotel, Friday 21 st February Drug-eluting stents Are they all equal?

HCS Working Group Seminars Macedonia Pallas Hotel, Friday 21 st February Drug-eluting stents Are they all equal? HCS Working Group Seminars Macedonia Pallas Hotel, Friday 21 st February 2014 Drug-eluting stents Are they all equal? Vassilis Spanos Interventional Cardiologist, As. Director 3 rd Cardiology Clinic Euroclinic

More information

Unprotected LM intervention

Unprotected LM intervention Unprotected LM intervention Guideline for COMBAT Seung-Jung Park, MD, PhD Professor of Internal Medicine, Seoul, Korea Current Recommendation for unprotected LMCA Stenosis Class IIb C in ESC guideline

More information

Stent Thrombosis in Bifurcation Stenting

Stent Thrombosis in Bifurcation Stenting Summit TCT Asia Pacific 2009 Stent Thrombosis in Bifurcation Stenting Associate Professor Tan Huay Cheem MBBS, M Med(Int Med), MRCP, FRCP(UK), FAMS, FACC, FSCAI Director, National University Heart Centre,

More information

Journal of Acupuncture and Tuina Science, 2012, v. 10 n. 2, p The original publication is available at

Journal of Acupuncture and Tuina Science, 2012, v. 10 n. 2, p The original publication is available at Title What is the origin of acupoint Author(s) Li, L; Yau, T; Yau, C Citation Journal of Acupuncture and Tuina Science, 2012, v. 10 n. 2, p. 125-127 Issued Date 2012 URL http://hdl.handle.net/10722/160714

More information

ΑΓΓΕΙΟΠΛΑΣΤΙΚΗ ΣΤΟ ΔΙΑΒΗΤΙΚΟ ΑΣΘΕΝΗ

ΑΓΓΕΙΟΠΛΑΣΤΙΚΗ ΣΤΟ ΔΙΑΒΗΤΙΚΟ ΑΣΘΕΝΗ ΑΓΓΕΙΟΠΛΑΣΤΙΚΗ ΣΤΟ ΔΙΑΒΗΤΙΚΟ ΑΣΘΕΝΗ Νίκος Μεζίλης MD, FESC Κλινική Άγιος Λουκάς Why diabetes is associated with restenosis endothelial dysfunction metabolic alterations accelerated platelet deposition

More information

Acute Glomerular Nephritis. Mao Jianhua, Department of Nephrology, The Children Hospital of Zhejiang University,

Acute Glomerular Nephritis. Mao Jianhua, Department of Nephrology, The Children Hospital of Zhejiang University, Acute Glomerular Nephritis Mao Jianhua, Department of Nephrology, The Children Hospital of Zhejiang University, maojh88@gmail.com DEFINITION APSGN is a immune-mediated inflammation disease with the mechanism

More information

Bosworth, /1966. Clemmer, 1966 Driscoll McCorkle & Korn 1954 Ohlin 1956 Wheeler 1961 U U-shaped curve Wheeler

Bosworth, /1966. Clemmer, 1966 Driscoll McCorkle & Korn 1954 Ohlin 1956 Wheeler 1961 U U-shaped curve Wheeler 关于服刑人员适应监狱生活的经验性研究起源于 20 世纪的美国之后, 社 会学家开始用人类学方法研究, 然而在这些研究中, 关于女性服刑人员监狱适应的研究较 少, 并被当做男性服刑人员 附属物 来比较, 此后有学者开始关注监狱环境以及社会文化背 景对于女性服刑人员监狱适应性状况的影响本文通过回顾与反思认为, 对女性应从两个维 度即适应监狱制度环境和适应服刑人员群体或服刑人员亚文化入手并从中探讨两者间关

More information

大舜政策研究中心 Dashun Policy Research Centre Ltd Annual Conference 2012

大舜政策研究中心 Dashun Policy Research Centre Ltd Annual Conference 2012 香港樂健會社 Happy Health Society in association with 大舜政策研究中心 Dashun Policy Research Centre Ltd Annual Conference 2012 人人健康由我做起 中西結合預防癌症 Prevention of Cancer East Meets West Approaches 2012 年 12 月 22 日 ( 星期六

More information

Non-LM bifurcation studies of importance in 2011

Non-LM bifurcation studies of importance in 2011 7th European Bifurcation Club 14-15 October 2011 LISBON Goran Stankovic MD, PhD Non-LM bifurcation studies of importance in 2011 October 15 th : 08:00 08:10 DKCRUSH-II: A Prospective Randomized Trial of

More information

Interferon-gamma and interleukin-10 levels in serum and saliva are related to different types of oral lichen planus

Interferon-gamma and interleukin-10 levels in serum and saliva are related to different types of oral lichen planus 中国组织工程研究第 19 卷第 2 期 2015 01 08 出版 Chinese Journal of Tissue Engineering Research January 8, 2015 Vol.19, No.2 Interferon-gamma and interleukin-10 levels in serum and saliva are related to different types

More information

DES In-stent Restenosis

DES In-stent Restenosis DES In-stent Restenosis Roxana Mehran, MD Columbia University Medical Center The Cardiovascular Research Foundation DES Restenosis Mechanisms Predictors Morphological patterns Therapy approach Mechanisms

More information

PCI for Left Main Coronary Artery Stenosis. Jean Fajadet Clinique Pasteur, Toulouse, France

PCI for Left Main Coronary Artery Stenosis. Jean Fajadet Clinique Pasteur, Toulouse, France PCI for Left Main Coronary Artery Stenosis Jean Fajadet Clinique Pasteur, Toulouse, France Athens, October 19, 2018 Left Main Coronary Artery Disease Significant unprotected left main coronary artery disease

More information

Stent Thrombosis: Patient, Procedural, and Stent Factors. Eugene Mc Fadden Cork, Ireland

Stent Thrombosis: Patient, Procedural, and Stent Factors. Eugene Mc Fadden Cork, Ireland Stent Thrombosis: Patient, Procedural, and Stent Factors Eugene Mc Fadden Cork, Ireland Definitions Early 1 yr TAXUS >6months CYPHER Incidence and Timing BMS Registry data

More information

Drug Eluting Stents: an update Abbott Vascular. All rights reserved.

Drug Eluting Stents: an update Abbott Vascular. All rights reserved. Drug Eluting Stents: an update DES: Science and Education for Better Practice--Introduction The clinical benefits of DES in reducing the risk of restenosis are well established. Recently the safety profile

More information

A Large Prospective Randomized Trial of DES vs BMS in Patients with STEMI

A Large Prospective Randomized Trial of DES vs BMS in Patients with STEMI HORIZONS-AMI: A Large Prospective Randomized Trial of DES vs BMS in Patients with STEMI Gregg W. Stone MD Columbia University Medical Center Cardiovascular Research Foundation Disclosures Gregg W. Stone

More information

Update on AIDS in China

Update on AIDS in China Update on AIDS in China Kong-Lai Zhang, MD Professor, Department of Epidemiology, Peking Union Medical College Beijing, CHINA March, 2013 1 HIV epidemic in Asia General Population Family Bridge Population

More information

Perspective of LM stenting with Current registry and Randomized Clinical Data

Perspective of LM stenting with Current registry and Randomized Clinical Data Asian Pacific TCT Perspective of LM stenting with Current registry and Randomized Clinical Data Patrick W. Serruys MD PhD Yoshinobu Onuma MD Seung-Jung Park MD, PhD 14:48-15:00, 2009 Symposium Arena, Level

More information

Diseases of the Urinary System. Wang Yishu Department of Pathology Basic Medical School

Diseases of the Urinary System. Wang Yishu Department of Pathology Basic Medical School Diseases of the Urinary System Wang Yishu Department of Pathology Basic Medical School Introduction Anatomy and Histology of Urinary System Urinary System Kidney Bladder Ureter Urethra Functions of kidney

More information

PCI for LMCA lesions A Review of latest guidelines and relevant evidence

PCI for LMCA lesions A Review of latest guidelines and relevant evidence HCS Working Group Seminars Met Hotel, Thursday 14 th February 2013 PCI for LMCA lesions A Review of latest guidelines and relevant evidence Vassilis Spanos Interventional Cardiologist, As. Director 3 rd

More information

Clinical Value of OCT. Guidance for Coronary Stenting. Giulio Guagliumi, MD

Clinical Value of OCT. Guidance for Coronary Stenting. Giulio Guagliumi, MD Clinical Value of OCT Guidance for Coronary Stenting Giulio Guagliumi, MD 100 % Endovascular Imaging Indications of use 87.5 % 75 % 57.5 % 50 % 45 % 25 % 15 % 0 Lesion morphology Stent optimization Lesion

More information

Unit1 What s the matter? 东乌旗蒙中 --- 苏丽雅

Unit1 What s the matter? 东乌旗蒙中 --- 苏丽雅 Unit1 What s the matter? 东乌旗蒙中 --- 苏丽雅 body feet tooth teeth ear eye head face nose mouth head hand knee t leg foot finger healthy neck shoulder arm back sing a song 1a Look at the picture. Write the

More information

Catch-up Phenomenon: Insights from Pathology

Catch-up Phenomenon: Insights from Pathology Catch-up Phenomenon: Insights from Pathology Michael Joner, MD CVPath Institute Inc. Gaithersburg, MD USA Path Lessons learned from the BMS and DES (1 st Gen) era Neointimal Thickness [mm] In Stent Re

More information

生物工程学报 Chin J Biotech 2009, July 25; 25(7): journals.im.ac.cn Chinese Journal of Biotechnology ISSN

生物工程学报 Chin J Biotech 2009, July 25; 25(7): journals.im.ac.cn Chinese Journal of Biotechnology ISSN 生物工程学报 Chin J Biotech 2009, July 25; 25(7): 1035-1041 journals.im.ac.cn Chinese Journal of Biotechnology ISSN 1000-3061 cjb@im.ac.cn 2009 Institute of Microbiology, CAS & CSM, All rights reserved 医学与免疫生物技术

More information

课程四 : 药物共晶 - 药物晶型开发的 新热点

课程四 : 药物共晶 - 药物晶型开发的 新热点 晶云药物 2011 年第一届晶型专题技术培训 课程四 : 药物共晶 - 药物晶型开发的 新热点 主讲人 : 陈敏华博士, 首席执行官 Crystal Pharmatech 苏州晶云药物科技有限公司 Email:sales@crystalpharmatech.com 电话 :0512-69561921 1 提纲 药物共晶简介 为何要开发药物共晶? 共晶发展历史 共晶的定义和表征 形成共晶的方法 药物共晶的案例分析

More information

Moins de 6 mois d antiagrégants après DES?

Moins de 6 mois d antiagrégants après DES? Moins de 6 mois d antiagrégants après DES? High Tech - Marseille 25 au 27 janvier 2011 Marie-Claude MORICE, MD, FESC, FACC Massy, France Pas de conflit d interet Was optimal duration of DAPT already established

More information

DUREE de la BITHERAPIE dans les ETUDES LEADERS. J BERLAND Clinique Saint Hilaire ROUEN

DUREE de la BITHERAPIE dans les ETUDES LEADERS. J BERLAND Clinique Saint Hilaire ROUEN DUREE de la BITHERAPIE dans les ETUDES LEADERS J BERLAND Clinique Saint Hilaire ROUEN LEADERS all-comers Trial Design Stable and ACS Patients Undergoing PCI Assessor-blind 1:1 Randomisation N=1700 Patients

More information

1. Original protocol, final protocol, summary of changes. (highlighted in. 2. Original statistical analysis plan, final statistical analysis plan,

1. Original protocol, final protocol, summary of changes. (highlighted in. 2. Original statistical analysis plan, final statistical analysis plan, Protocol This supplement contains the following items: 1. Original protocol, final protocol, summary of changes. (highlighted in yellow track change in the final protocol). 2. Original statistical analysis

More information

Metabolism Of Calcium and Phosphorus

Metabolism Of Calcium and Phosphorus Metabolism Of Calcium and Phosphorus Three hormones crucially involved: Vitamin D (1,25- (OH)2-D3) Parathyroid hormone (PTH) Calcitonin (CT) Calcium Is Needed For: Bone Matrix (70% CaOH in form of Hydroxyapatite)

More information

Fractures of Extremities (Upper Limbs) Dr. Zhong gang. Department of Orthopaedic Surgery West China Hospital of Sichuan University

Fractures of Extremities (Upper Limbs) Dr. Zhong gang. Department of Orthopaedic Surgery West China Hospital of Sichuan University Fractures of Extremities (Upper Limbs) Dr. Zhong gang Department of Orthopaedic Surgery West China Hospital of Sichuan University 七 上肢骨折和手外伤 (Upper Limbs Fracture and Hand Injury) 一. 知识点与教学要求掌握 : 1. 肱骨干骨折,

More information

LM stenting - Cypher

LM stenting - Cypher LM stenting - Cypher Left main stenting with BMS Since 1995 Issues in BMS era AMC Restenosis and TLR (%) 3 27 TLR P=.282 Restenosis P=.71 28 2 1 15 12 Ostium 5 4 Shaft Bifurcation Left main stenting with

More information

EXCEL vs. NOBLE: How to Treat Left Main Disease in 2017 AATS International Cardiovascular Symposium December 8-9, 2017

EXCEL vs. NOBLE: How to Treat Left Main Disease in 2017 AATS International Cardiovascular Symposium December 8-9, 2017 EXCEL vs. NOBLE: How to Treat Left Main Disease in 2017 AATS International Cardiovascular Symposium December 8-9, 2017 Igor F. Palacios, MD Director of Interventional Cardiology Professor of Medicine Massachusetts

More information

I am glad to share my knowledge with you, and I want you to become a master of the subject, pharmacology Antiarrhythmic drugs 抗心律失常药 朱玲 四川大学华西医学中心 zhu

I am glad to share my knowledge with you, and I want you to become a master of the subject, pharmacology Antiarrhythmic drugs 抗心律失常药 朱玲 四川大学华西医学中心 zhu I am glad to share my knowledge with you, and I want you to become a master of the subject, pharmacology Antiarrhythmic drugs 抗心律失常药 朱玲 四川大学华西医学中心 zhuling529@163.com 教学要求 1. 了解心脏的电生理特性 2. 熟悉心律失常的发生机制 3.

More information

Dual Antiplatelet Therapy Made Practical

Dual Antiplatelet Therapy Made Practical Dual Antiplatelet Therapy Made Practical David Parra, Pharm.D., FCCP, BCPS Clinical Pharmacy Program Manager in Cardiology/Anticoagulation VISN 8 Pharmacy Benefits Management Clinical Associate Professor

More information

COMPARE Trial Elvin Kedhi Maasstad Ziekenhuis Rotterdam The Netherlands

COMPARE Trial Elvin Kedhi Maasstad Ziekenhuis Rotterdam The Netherlands COMPARE Trial Elvin Kedhi Maasstad Ziekenhuis Rotterdam The Netherlands TCTAP 2010 Seoul, Korea Disclosures Research Foundation of the Cardiology Department has received unrestricted research grants from:

More information

Can Acupuncture Really benefit Stroke?

Can Acupuncture Really benefit Stroke? Can Acupuncture Really benefit Stroke? 朱氏头皮针介绍与中风治疗应用的讨论 朱明清 Ming Qing Zhu 蕭慕如 Moyee Siu 1 Strokes statistics 中风的统计 795,000 per year in USA; 50,000 in Canada 1 per 45 sec, 1 die every 4 min in USA 15 million

More information

IN-STENT RESTENOSIS. K.Boerlage-van Dijk CarVasZ 2014

IN-STENT RESTENOSIS. K.Boerlage-van Dijk CarVasZ 2014 IN-STENT RESTENOSIS K.Boerlage-van Dijk CarVasZ 2014 Definition ISR Angiographic: recurrent diameter stenosis >50% at the stent segment or edges (5-mm segments adjacent to stent) Mehran system morphological

More information

Pharmaceutical Biotechnology 西安电子科技大学夏玉琼 Insulin and human growth hormone By Yuqiong Xia 5/19/2017

Pharmaceutical Biotechnology 西安电子科技大学夏玉琼 Insulin and human growth hormone By Yuqiong Xia 5/19/2017 Pharmaceutical Biotechnology Insulin and human growth hormone By Yuqiong Xia 5/19/2017 生物技术制药 2 技术基础 生物技术药物 生物技术制药概念药物的开发药物的生产细胞因子生长因子激素类药物血液制品和治疗性酶抗体 疫苗和佐剂核酸药物 药物的发现 专利的申请临床前试验临床试验生物药物的来源生物药物的生产和纯化生物药物的分析干扰素白介素造血生长因子

More information

Shedding light on stent thrombosis

Shedding light on stent thrombosis Editorial Shedding light on stent thrombosis Tawfiq Choudhury 1,2, Rodrigo Bagur 1,2, Ashlay A. Huitema 1,2, Amir Solomonica 1,2, Shahar Lavi 1,2 1 Department of Medicine, Western University, London, ON,

More information

Antiplatelet Therapy After PCI: How Much and How Long?

Antiplatelet Therapy After PCI: How Much and How Long? Antiplatelet Therapy After PCI: How Much and How Long? Adnan Kastrati Deutsches Herzzentrum, Munich, GERMANY Antiplatelet Therapy after PCI: How much and how long? The simplest and extreme response: Give

More information

2015 年 4 月 25 日 GRE 考试 语文部分 真题回忆答案解析 小站教育独家出品 版权所有翻录必究

2015 年 4 月 25 日 GRE 考试 语文部分 真题回忆答案解析 小站教育独家出品 版权所有翻录必究 2015 年 4 月 25 日 GRE 考试 语文部分 真题回忆答案解析 小站教育独家出品 版权所有翻录必究 [4.25GRE 填空部分 ]: 1.The subject who were engaged in more difficult tasks deterioration in iheir performance over times, and therefore the need to concentrate

More information

INTRODUCTION. Key Words:

INTRODUCTION. Key Words: Original Acta Cardiol Sin 2007;23:247 53 The Efficacy and Safety of Angio-Seal Percutaneous Femoral Artery Closure Device after Diagnostic and Therapeutic Cardiac Catheterizations A Single Center s Experience

More information

Dietary Guidelines for Chinese Residents (2016): comments and comparisons

Dietary Guidelines for Chinese Residents (2016): comments and comparisons Wang et al. / J Zhejiang Univ-Sci B (Biomed & Biotechnol) 2016 17(9):649-656 649 Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology) ISSN 1673-1581 (Print); ISSN 1862-1783 (Online) www.zju.edu.cn/jzus;

More information

PCI for Bifurcation Coronary Lesion

PCI for Bifurcation Coronary Lesion PCI for Bifurcation Coronary Lesion Bifurcation Lesions PCI is Challenging Higher acute complication Lower success rates Higher restenosis & TLR Restenosis Rate 21 ~ 57% TLR 8 ~ 43% Event Free Survival

More information

PCI for In-Stent Restenosis. CardioVascular Research Foundation

PCI for In-Stent Restenosis. CardioVascular Research Foundation PCI for In-Stent Restenosis ISR of BMS Patterns of In-Stent Restenosis Pattern I : Focal Type IA: Articulation / Gap Type IB: Marginal Type IC: Focal body Type ID: Multifocal Pattern II,III,IV : Diffuse

More information

Contemporary therapy of bifurcation lesions

Contemporary therapy of bifurcation lesions Contemporary therapy of bifurcation lesions Dr Angela Hoye MB ChB PhD MRCP Interventional Cardiologist Kingston-upon-Hull, UK Hull The challenge of bifurcations Risk of peri-procedural infarction Relatively

More information

Invasive fungal infection in allogeneic hematopoietic stem cell transplant recipients: single center experiences of 12 years *

Invasive fungal infection in allogeneic hematopoietic stem cell transplant recipients: single center experiences of 12 years * 796 Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology) ISSN 1673-1581 (Print); ISSN 1862-1783 (Online) www.zju.edu.cn/jzus; www.springerlink.com E-mail: jzus@zju.edu.cn Invasive fungal

More information

Three-Year Clinical Outcomes with Everolimus-Eluting Bioresorbable Scaffolds: Results from the Randomized ABSORB III Trial Stephen G.

Three-Year Clinical Outcomes with Everolimus-Eluting Bioresorbable Scaffolds: Results from the Randomized ABSORB III Trial Stephen G. Three-Year Clinical Outcomes with Everolimus-Eluting Bioresorbable Scaffolds: Results from the Randomized ABSORB III Trial Stephen G. Ellis MD Dean J. Kereiakes MD and Gregg W. Stone MD for the ABSORB

More information

Drug Eluting Stents: Bifurcation and Left Main Approach

Drug Eluting Stents: Bifurcation and Left Main Approach TCT Asia 2006 Drug Eluting Stents: Bifurcation and Left Main Approach Eberhard Grube MD FACC, FSCAI Heart Center,, Germany Stanford University, School of Medicine, CA, USA DES in High Risk Lesions TAXUS

More information

Scientific Data Sharing Platform

Scientific Data Sharing Platform Qingdao China-US Roundtable Conference on Scientific Data Sharing Healthy World 2020 Scientific Data Sharing Platform Depei Liu, MD, Ph.D. Chinese Academy of Medical Sciences 2009-3-23 1 I will discuss

More information

Field Control Efficiency of a Microbial Seed Dressing Agent of Bacillus Strain on Soybean Fungal Root Rot

Field Control Efficiency of a Microbial Seed Dressing Agent of Bacillus Strain on Soybean Fungal Root Rot 微生物学通报 JUN 0, 009, 36(6): 84~846 Microbiology tongbao@im.ac.cn 研究报告 009 by Institute of Microbiology, CAS Field Control Efficiency of a Microbial Seed Dressing Agent of Bacillus Strain on Soybean Fungal

More information

Pulmonary Rehabilitation 肺康复 许灵玲

Pulmonary Rehabilitation 肺康复 许灵玲 Pulmonary Rehabilitation 肺康复 许灵玲 Contents 目录 What s pulmonary rehabilitation? Who are the members of the Interdisciplinary Team? Who benefits from pulmonary rehabilitation? What s the goals of pulmonary

More information