Effects of mechanical ventilation on organ function. Masterclass ICU nurses
|
|
- Austen Townsend
- 6 years ago
- Views:
Transcription
1 Effects of mechanical ventilation on organ function Masterclass ICU nurses
2 Case Male, 60 - No PMH - L 1.74 m and W 85 kg Pneumococcal pneumonia Stable hemodynamics - No AKI MV in prone position (PEEP 16 - FiO2 60%) Intensivist / fellow / nurses discuss the following questions at the bedside:
3 Questions What is the effect of mechanical ventilation on right ventricular function? What is the effect of mechanical ventilation on left ventricular function? Besides its effect on the circulation, what are the effects of MV on kidney function What are the effects of MV on cerebral blood flow and intracranial pressure?
4 Cardiac output = Venous return
5 What happens with changing metabolic needs Cardiac output 5 L HR 75/min SV 66.7 ml EF 65% Cardiac output 20 L HR 150/min SV 77 ml EF 75% = 11.5 L Large increase in CO mainly explained by in venous return
6 Venous return curve 6 5 Venous return CO (l/min) CVP (mm Hg)
7 It is not arterial pressure that drives venous return MAP (mmhg) and SVI (ml/m2) MAP (mmhg) SVI (ml/m2) *** *** *** 0 Baseline 1 Hr 4 Hrs 6 Hrs Terlipressin in septic shock Albanèse J. Crit Care Med 2005;33:
8 SVC Main function of RV is to keep RAP low Towards RV 0 RAP = 0 After fluid challenge Venous resistance IVC VR = MSFP - RAP Venous resistance mm Hg 1,8 1,6 1,4 1,2 1 0,8 0,6 0,4 0,2 0 Before After Mean Systemic Filling Pressure Cecconi M. Intensive Care Med 2013;39:
9 VCS Pleura Pericard RA VCI 100 Relative increase compared to airway pressure (%) Pleural pressure Pericardial pressure Central venous pressure Lansdorp B. Crit Care Med 2014;42:
10 Tv 400 ml PEEP 16 MSFP VCS Pleura Pericard MAP 22 cm H20 RA 6.5 RA mmhg VCI
11 What happens with RV afterload? Extra-alveolar blood vessels Alveolar blood vessels Pulmonary vascular resistance Total vascular resistance Alveolar blood vessels Extra-alveolar blood vessels RV FRC TLC
12 Do you think RV failure is improved by proning?
13 IAP VR PaO2 Central BV RV preload Recruitment PVR RV afterload LV preload No No CO increase Yes Preload reserve CO increase Jozwiak M. Am J Respir Crit Care Med 2013;188:
14 ARDS (N = 16) 5,5 P < P < 0.05 CI (l/min/m2) 4,5 3,5 DO2 (ml/min/m2) ,5 Supine Prone 400 Supine Prone IAP (mmhg) P < 0.05 GFRI (ml/min) NS 6 Supine Prone 0 Supine Prone Hering R. Anesth Analg 2001;92:
15 Prone position and RV failure Before PP After 18 h of PP P-value SAP (mm Hg) 115 ± ± 14 NS HR (bpm) 107 ± ± 13 0,019 CI (l/min/m 2 ) 2.9 ± ± 0.8 0,013 RVEDA/LVEDA 0.91 ± ± 0.21 < 0,001 Septal eccentricity 1.5 ± ± 0.1 < 0,001 TR (n) 20 7 LVEDV (ml) 45 ± ± 21 < 0,001 LVEF (%) 58 ± ± 9 NS N = 21 Severe ARDS with PF < 100 Veillard-Baron A. Chest 2007;132:
16 What happens with LV afterload? Spontaneous ventilation LV pressure should increase 80 mmhg to open AV Mechanical ventilation LV pressure should increase 60 mmhg to open AV
17 What happens with LV afterload? Positive pressure ventilation may decrease LV afterload Alveolar pressure 20 Alveolar pressure
18 MV for cardiogenic shock IABP IABP + MV P-value UP (ml/uur) 55.1 ± ± 38 < RRsys (mmhg) 104 ± ± 10 NS CI (l/min/m2) 3.2 ± ± PCWP (mmhg) 21 ± 5 16 ± Heart rate 104 ± ± Dobutamine 6.7 ± ± ph 7.3 ± ± Intensive Care Med 1999;25:
19 Effects on renal function Hemodynamic Slower loss of fluid from vasculature Normal Rapid vascular refilling with fluid removal Cardiac output Normal oncotic pressure Arterial Venous CVP Normal intersitium Neurohormonal Interstitial oedema Fluid therapy Ultrafiltration Renal blood flow Low oncotic pressure Increased capillary permeability Plasma protein leak Hypoalbuminaemia Decreased GFR Rapid loss of fluid from vasculature Systemic inflammation Slow vascular refilling with fluid removal Fluid retention
20 PCO2 PO2 Brain metabolism ICP Jugular vein Autonomic centers CVP Resistance vessels Conduit vessels CO SVR MAP
21 Starling resistor model ICP ICP An increase in ICP raises outflow pressure and capillary fluid flux Thoracic pressure only increases ICP if CVP > ICP
22 PEEP and ICP increase ICP (mm Hg) ** ** 5 0 PEEP 0 PEEP 5 PEEP 10 PEEP 15 ICP normal ICP increased McGuire G, et al. Crit Care Med 1997;25:
23 PEEP and ICP increase mm Hg PEEP 0 tot 5 PEEP 6-10 PEEP ICP CPP Huynh T, et al. J Trauma 2002;53:
24 Conclusions MV decreases RV and LV preload MV has variable effects on RV and LV afterload MV decreases renal function MV decreases cerebral blood flow and has a variable effect on ICP
Right Ventricle. Interaction with the pulmonary circulation. Fellowship Intensive Care Nijmegen
Right Ventricle Interaction with the pulmonary circulation Fellowship Intensive Care Nijmegen Normal right ventricle PAP 25/10 EF 62 ± 8% Constant low pressure perfusion of the lung Maintain low RA pressure
More informationARDS Assisted ventilation and prone position. ICU Fellowship Training Radboudumc
ARDS Assisted ventilation and prone position ICU Fellowship Training Radboudumc Fig. 1 Physiological mechanisms controlling respiratory drive and clinical consequences of inappropriate respiratory drive
More informationHow to resuscitate the patient in early sepsis? A physiological approach. J.G. van der Hoeven, Nijmegen
How to resuscitate the patient in early sepsis? A physiological approach J.G. van der Hoeven, Nijmegen Disclosure interests speaker (potential) conflict of interest Potentially relevant relationships with
More informationRounds in the ICU. Eran Segal, MD Director General ICU Sheba Medical Center
Rounds in the ICU Eran Segal, MD Director General ICU Sheba Medical Center Real Clinical cases (including our mistakes) Emphasis on hemodynamic monitoring Usually no single correct answer We will conduct
More informationSepsis and septic shock Practical hemodynamic consequences. Intensive Care Training Program Radboud University Medical Centre Nijmegen
Sepsis and septic shock Practical hemodynamic consequences Intensive Care Training Program Radboud University Medical Centre Nijmegen Septic cardiomyopathy Present in > 50% and often masked by low vascular
More informationCardiopulmonary System
Dana Oakes, BA, RRT NPS Author/Speaker Cardiopulmonary System Main Purpose Main Function Main Goal Oxygen Delivery Adequate Perfusion (deliver adequate oxygen and nutrients; remove metabolic waste) Tissue
More informationTopics to be Covered. Cardiac Measurements. Distribution of Blood Volume. Distribution of Pulmonary Ventilation & Blood Flow
Topics to be Covered MODULE F HEMODYNAMIC MONITORING Cardiac Output Determinants of Stroke Volume Hemodynamic Measurements Pulmonary Artery Catheterization Control of Blood Pressure Heart Failure Cardiac
More informationProf. Dr. Iman Riad Mohamed Abdel Aal
The Use of New Ultrasound Indices to Evaluate Volume Status and Fluid Responsiveness in Septic Shock Patients Thesis Submitted for partial fulfillment of MD degree in Anesthesiology, Surgical Intensive
More informationIntroduction. Invasive Hemodynamic Monitoring. Determinants of Cardiovascular Function. Cardiovascular System. Hemodynamic Monitoring
Introduction Invasive Hemodynamic Monitoring Audis Bethea, Pharm.D. Assistant Professor Therapeutics IV January 21, 2004 Hemodynamic monitoring is necessary to assess and manage shock Information obtained
More informationHemodynamic Monitoring Pressure or Volumes? Antonio Pesenti University of Milan Italy
Hemodynamic Monitoring Pressure or Volumes? Antonio Pesenti University of Milan Italy antonio.pesenti@unimi.it CCCF 2017 Is it useful? YES: CVP It is an important diagnostic element! Your best guess CVP
More informationFluids: occult effects. S Magder Department of Critical Care, McGill University Health Centre
Fluids: occult effects S Magder Department of Critical Care, McGill University Health Centre Why is volume important? 1. Water is essential to dissolve substances and allow them to diffuse 2. Necessary
More informationWet Lungs Dry lungs Impact on Outcome in ARDS. Charlie Phillips MD Division of PCCM OHSU 2009
Wet Lungs Dry lungs Impact on Outcome in ARDS Charlie Phillips MD Division of PCCM OHSU 2009 Today s talk Pathophysiology of ARDS The case for dry Targeting EVLW Disclosures Advisor for Pulsion Medical
More informationSepsis and septic shock
Sepsis and septic shock Practical hemodynamic consequences Intensive Care Training Program Radboud University Medical Centre Nijmegen Septic cardiomyopathy Present in > 50% and often masked by low vascular
More informationMechanical Ventilation & Cardiopulmonary Interactions: Clinical Application in Non- Conventional Circulations. Eric M. Graham, MD
Mechanical Ventilation & Cardiopulmonary Interactions: Clinical Application in Non- Conventional Circulations Eric M. Graham, MD Background Heart & lungs work to meet oxygen demands Imbalance between supply
More informationCardiorespiratory Interactions:
Cardiorespiratory Interactions: The Heart - Lung Connection Jon N. Meliones, MD, MS, FCCM Professor of Pediatrics Duke University Medical Director PCVICU Optimizing CRI Cardiorespiratory Economics O2:
More informationMechanical ventilation induced or exacerbated right ventricular failure
Mechanical ventilation induced or exacerbated right ventricular failure Toronto 2016 Jesse Hall MD Professor of Medicine, Anesthesia & Critical Care University of Chicago Faculty Disclosures Dr. Hall
More informationVentriculo-arterial coupling and diastolic elastance. MasterclassIC Schiermonnikoog 2015
Ventriculo-arterial coupling and diastolic elastance MasterclassIC Schiermonnikoog 2015 Ventriculo-arterial coupling Dynamic interaction between heart and systemic circulation (modulation of compliance
More informationFUNDAMENTALS OF HEMODYNAMICS, VASOACTIVE DRUGS AND IABP IN THE FAILING HEART
FUNDAMENTALS OF HEMODYNAMICS, VASOACTIVE DRUGS AND IABP IN THE FAILING HEART CINDY BITHER, MSN, ANP, ANP, AACC, CHFN CHIEF NP, ADV HF PROGRAM MEDSTAR WASHINGTON HOSPITAL CENTER CONFLICTS OF INTEREST NONE
More informationChapter 21. Flail Chest. Mosby items and derived items 2011, 2006 by Mosby, Inc., an affiliate of Elsevier Inc.
Chapter 21 Flail Chest 1 Figure 21-1. Flail chest. Double fractures of three or more adjacent ribs produce instability of the chest wall and paradoxical motion of the thorax. Inset, Atelectasis, a common
More informationFluid responsiveness and extravascular lung water
Fluid responsiveness and extravascular lung water Prof. Jean-Louis TEBOUL Medical ICU Bicetre hospital University Paris-South France Conflicts of interest Member of the Medical Advisory Board of Maquet/Pulsion
More informationManagement of refractory ARDS. Saurabh maji
Management of refractory ARDS Saurabh maji Refractory hypoxemia as PaO2/FIO2 is less than 100 mm Hg, inability to keep plateau pressure below 30 cm H2O despite a VT of 4 ml/kg development of barotrauma
More informationRelax and Learn At the Farm 2012
Relax and Learn At the Farm Session 9: Invasive Hemodynamic Assessment and What to Do with the Data Carol Jacobson RN, MN Cardiovascular Nursing Education Associates Function of CV system is to deliver
More informationRadboud University Nijmegen Medical Centre Why measure cardiac output in critically ill children?
Radboud University Nijmegen Medical Centre Why measure cardiac output in critically ill children? J. Lemson Anesthesiologist/(pediatric)intensivist Case; Girl 2 years, 12 kg, severe meningococcal septic
More informationUPMC Critical Care
UPMC Critical Care www.ccm.pitt.edu Cardiovascular insufficiency with Initiation and Withdrawal of Mechanical Ventilation Michael R. Pinsky, MD, Dr hc Department of Critical Care Medicine University of
More informationGoal-directed vs Flow-guidedresponsive
Goal-directed vs Flow-guidedresponsive therapy S Magder Department of Critical Care, McGill University Health Centre Flow-directed vs goal directed strategy for management of hemodynamics S Magder Curr
More information7/4/2015. diffuse lung injury resulting in noncardiogenic pulmonary edema due to increase in capillary permeability
Leanna R. Miller, RN, MN, CCRN-CMC, PCCN-CSC, CEN, CNRN, CMSRN, NP Education Specialist LRM Consulting Nashville, TN Objectives Identify the 5 criteria for the diagnosis of ARDS. Discuss the common etiologies
More informationFunctional Hemodynamic Monitoring and Management A practical Approach
Functional Hemodynamic Monitoring and Management A practical Approach Daniel A. Reuter Center of Anesthesiology and Intensive Care Medicine Hamburg-Eppendorf University Hospital Hamburg, Germany Euronaesthesia
More informationReverse (fluid) resuscitation Should we be doing it? NAHLA IRTIZA ISMAIL
Reverse (fluid) resuscitation Should we be doing it? NAHLA IRTIZA ISMAIL 65 Male, 60 kg D1 in ICU Admitted from OT intubated Diagnosis : septic shock secondary to necrotising fasciitis of the R lower limb
More informationAssessing Preload Responsiveness Using Arterial Pressure Based Technologies. Patricia A. Meehan, RN, MS Education Consultant Edwards Lifesciences, LLC
Assessing Preload Responsiveness Using Arterial Pressure Based Technologies Patricia A. Meehan, RN, MS Education Consultant Edwards Lifesciences, LLC Content Description : Fluid administration is a first
More informationECMO: a breakthrough in care for respiratory failure. PD Dr. Thomas Müller Regensburg no conflict of interest
ECMO: a breakthrough in care for respiratory failure? PD Dr. Thomas Müller Regensburg no conflict of interest 1 Overview Mortality of severe ARDS Indication for ECMO PaO 2 /FiO 2 Efficiency of ECMO: gas
More informationCardiovascular Management of Septic Shock
Cardiovascular Management of Septic Shock R. Phillip Dellinger, MD Professor of Medicine Robert Wood Johnson Medical School/UMDNJ Director, Critical Care Medicine and Med/Surg ICU Cooper University Hospital
More informationHemodynamic improvement upon levosimendan treatment in low cardiac output patients following coronary artery bypass graft
Hemodynamic improvement upon levosimendan treatment in low cardiac output patients following coronary artery bypass graft M. Buerke, K. Krohe, M. Russ, C. Schneider, H. Lemm, R. Prondzinsky, I. Friedrich,
More informationUsing Functional Hemodynamic Indicators to Guide Fluid Therapy
CE 2.6 HOURS Continuing Education Using Functional Hemodynamic Indicators to Guide Fluid Therapy A more accurate and less invasive way to gauge responsiveness to iv volume replacement. OVERVIEW: Hemodynamic
More informationThe Use of Dynamic Parameters in Perioperative Fluid Management
The Use of Dynamic Parameters in Perioperative Fluid Management Gerard R. Manecke Jr., M.D. Chief, Cardiac Anesthesia UCSD Medical Center San Diego, CA, USA Thanks to Tom Higgins, M.D. 1 Goals of today
More informationACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) Rv
ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) Rv.8.18.18 ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) SUDDEN PROGRESSIVE FORM OF ACUTE RESPIRATORY FAILURE ALVEOLAR CAPILLARY MEMBRANE BECOMES DAMAGED AND MORE
More informationPatrick C. Cullinan, DO, NBPNS, FCCM, FACOEP, FACOI Associate Clinical Professor, UIWSOM, San Antonio, Texas Adjunct Assistant Professor, University
Patrick C. Cullinan, DO, NBPNS, FCCM, FACOEP, FACOI Associate Clinical Professor, UIWSOM, San Antonio, Texas Adjunct Assistant Professor, University of Texas Health Science Center, Department of Emergency
More informationHow to apply advanced hemodynamic parameters in the ICU 奇美醫學中心
How to apply advanced hemodynamic parameters in the ICU 奇美醫學中心 加護醫學部 楊俊杰醫師 Outlines Case presentation PiCCOmonitor Edwards EV 1000 Case presentation Day 1-At ED (1) 72 y/o male C.C: shortness of breath,
More informationCardiac output and Venous Return. Faisal I. Mohammed, MD, PhD
Cardiac output and Venous Return Faisal I. Mohammed, MD, PhD 1 Objectives Define cardiac output and venous return Describe the methods of measurement of CO Outline the factors that regulate cardiac output
More informationThe right heart: the Cinderella of heart failure
The right heart: the Cinderella of heart failure Piotr Ponikowski, MD, PhD, FESC Medical University, Centre for Heart Disease Clinical Military Hospital Wroclaw, Poland none Disclosure Look into the Heart
More informationSHOCK. Emergency pediatric PICU division Pediatric Department Medical Faculty, University of Sumatera Utara H. Adam Malik Hospital
SHOCK Emergency pediatric PICU division Pediatric Department Medical Faculty, University of Sumatera Utara H. Adam Malik Hospital 1 Definition Shock is an acute, complex state of circulatory dysfunction
More informationBedside assessment of fluid status
Bedside assessment of fluid status 2nd AKI Academy October 18 th 2014 David Treacher Guy s & St Thomas NHS Trust Assessing the circulation - the 3 key questions v Is my patient adequately filled? v What
More informationSHOCK and the Trauma Victim. JP Pretorius Department of Surgery & SICU Steve Biko Academic Hospital.
SHOCK and the Trauma Victim JP Pretorius Department of Surgery & SICU Steve Biko Academic Hospital. Classification of Shock Cardiogenic - Myopathic Arrythmic Mechanical Hypovolaemic - Haemorrhagic Non-haemorrhagic
More informationa. Describe the physiological consequences of intermittent positive pressure ventilation and positive end-expiratory pressure.
B. 10 Applied Respiratory Physiology a. Describe the physiological consequences of intermittent positive pressure ventilation and positive end-expiratory pressure. Intermittent positive pressure ventilation
More informationCath Lab Essentials: Basic Hemodynamics for the Cath Lab and ICU
Cath Lab Essentials: Basic Hemodynamics for the Cath Lab and ICU Ailin Barseghian El-Farra, MD, FACC Assistant Professor, Interventional Cardiology University of California, Irvine Department of Cardiology
More informationAcute Liver Failure: Supporting Other Organs
Acute Liver Failure: Supporting Other Organs Michael A. Gropper, MD, PhD Professor of Anesthesia and Physiology Director, Critical Care Medicine University of California San Francisco Acute Liver Failure
More informationJan M. Headley, R.N. BS
Fluid First: Using PLR & SVV to Optimize Volume Jan M. Headley, R.N. BS Disclosure Director, Clinical Marketing & Professional Education Edwards Lifesciences Does this Patient NEED Fluid?? WE Have a Problem
More information9/19/2011. Damien Beilman, RRT Adult Clinical Specialist Wesley Medical Center. Epidural Hematoma: Lens Shaped.
Damien Beilman, RRT Adult Clinical Specialist Wesley Medical Center Epidural Hematoma: Lens Shaped. 1 Epidural Hematoma Subdural Hematoma: Crescent-shaped Subdural Hematoma 2 Cerebral Contusion Cause of
More informationPCV and PAOP Old habits die hard!
PCV and PAOP Old habits die hard! F Javier Belda MD, PhD Head of Department Associate Professor Anaesthesia and Critical Care Hospital Clínico Universitario Valencia (SPAIN) An old example TOBACO SMOKING
More informationTailored Volume Resuscitation in the Critically Ill is Achievable. Objectives. Clinical Case 2/16/2018
Tailored Volume Resuscitation in the Critically Ill is Achievable Heath E Latham, MD Associate Professor Fellowship Program Director Pulmonary and Critical Care Objectives Describe the goal of resuscitation
More informationDepartment of Intensive Care Medicine UNDERSTANDING CIRCULATORY FAILURE IN SEPSIS
Department of Intensive Care Medicine UNDERSTANDING CIRCULATORY FAILURE IN SEPSIS UNDERSTANDING CIRCULATORY FAILURE IN SEPSIS a mismatch between tissue perfusion and metabolic demands the heart, the vasculature
More informationLearning Objectives. 1. Indications versus contra-indications 2. CPAP versus NiVS 3. Clinical evidence
Learning Objectives 1. Indications versus contra-indications 2. CPAP versus NiVS 3. Clinical evidence Pre-hospital Non-invasive vventilatory support Marc Gillis, MD Imelda Bonheiden Our goal out there
More informationHemodynamic monitoring beyond cardiac output
Hemodynamic monitoring beyond cardiac output Prof Xavier MONNET Medical Intensive Care Unit Bicêtre Hospital Assistance publique Hôpitaux de Paris FRANCE Conflicts of interest Lilly GlaxoSmithKline Pulsion
More information(Peripheral) Temperature and microcirculation
(Peripheral) Temperature and microcirculation Prof. Jan Bakker MD, PhD Chair dept Intensive Care Adults jan.bakker@erasmusmc.nl www.intensivecare.me Intensive Care Med (2005) 31:1316 1326 DOI 10.1007/s00134-005-2790-2
More informationMaking vasopressors safer
Making vasopressors safer Requirements for safe vaspressor use In an ideal world 1. Knowledge of what constitutes optimal vasopressor dosing 2. A culture of cautiousness regarding vasopressors What do
More informationPiCCO based algorithms
European Society of Anaesthesiologists Annual Meeting 12.-15. June 2010, Helsinki, Finland PiCCO based algorithms Berthold Bein, MD, PhD, DEAA Department of Anaesthesiology and Intensive Care Medicine
More informationThe new ARDS definitions: what does it mean?
The new ARDS definitions: what does it mean? Richard Beale 7 th September 2012 METHODS ESICM convened an international panel of experts, with representation of ATS and SCCM The objectives were to update
More informationEjection across stenotic aortic valve requires a systolic pressure gradient between the LV and aorta. This places a pressure load on the LV.
Valvular Heart Disease Etiology General Principles Cellular and molecular mechanism of valve damage Structural pathology Functional pathology - stenosis/regurgitation Loading conditions - pressure/volume
More informationThe Vigileo monitor by Edwards Lifesciences supports both the FloTrac Sensor for continuous cardiac output and the Edwards PreSep oximetry catheter
1 2 The Vigileo monitor by Edwards Lifesciences supports both the FloTrac Sensor for continuous cardiac output and the Edwards PreSep oximetry catheter for continuous central venous oximetry (ScvO2) 3
More informationHeart Pump and Cardiac Cycle. Faisal I. Mohammed, MD, PhD
Heart Pump and Cardiac Cycle Faisal I. Mohammed, MD, PhD 1 Objectives To understand the volume, mechanical, pressure and electrical changes during the cardiac cycle To understand the inter-relationship
More informationNurse Driven Fluid Optimization Using Dynamic Assessments
Nurse Driven Fluid Optimization Using Dynamic Assessments 2016 1 WHAT WE BELIEVE We believe that clinicians make vital fluid and drug decisions every day with limited and inconclusive information Cheetah
More informationImpedance Cardiography (ICG) Method, Technology and Validity
Method, Technology and Validity Hemodynamic Basics Cardiovascular System Cardiac Output (CO) Mean arterial pressure (MAP) Variable resistance (SVR) Aortic valve Left ventricle Elastic arteries / Aorta
More informationTranspulmonary thermodilution in septic shock & ARDS
Transpulmonary thermodilution in septic shock & ARDS F Michard, MD, PhD Lea Michard Photography Disclosure Intensivist Pulsion, UPMED & Edwards Patents Transpulmonary thermodilution CVC, A line (femoral)
More informationRight Ventricular Failure: Prediction, Prevention and Treatment
Right Ventricular Failure: Prediction, Prevention and Treatment 3 rd European Training Symposium for Heart Failure Cardiologists and Cardiac Surgeons University Hospital Bern June 24-25, 2016 Disclosures:
More informationEjection across stenotic aortic valve requires a systolic pressure gradient between the LV and aorta. This places a pressure load on the LV.
Valvular Heart Disease General Principles Etiology Cellular and molecular mechanism of valve damage Structural pathology Functional pathology - stenosis/regurgitation Loading conditions - pressure/volume
More informationThe Septic Patient. Dr Arunraj Navaratnarajah. Renal SpR Imperial College NHS Healthcare Trust
The Septic Patient Dr Arunraj Navaratnarajah Renal SpR Imperial College NHS Healthcare Trust Objectives of this session Define SIRS / sepsis / severe sepsis / septic shock Early recognition of Sepsis The
More informationHemodynamics: Cardiac and Vascular Jeff Davis, RRT, RCIS
Hemodynamics: Cardiac and Vascular Jeff Davis, RRT, RCIS Program Director, Cardiovascular Technology Florida SouthWestern State College Fort Myers, FL Disclosures Speaker s Bureau: None Stockholder: None
More informationCase scenario V AV ECMO. Dr Pranay Oza
Case scenario V AV ECMO Dr Pranay Oza Case Summary 53 y/m, k/c/o MVP with myxomatous mitral valve with severe Mitral regurgitation underwent Mitral valve replacement with mini thoracotomy Pump time nearly
More informationGoal-directed resuscitation in sepsis; a case-based approach
Goal-directed resuscitation in sepsis; a case-based approach Jorge A Guzman, MD, FCCM Head, Section Critical Care Medicine Respiratory Institute Cleveland Clinic Foundation The challenges to managing septic
More informationMaternal and Fetal Physiology
Background Maternal and Fetal Physiology Anderson Lo, DO Fellow, Maternal-Fetal Medicine Wayne State University School of Medicine SEMCME Fetal Assessment Course July 20, 2018 Oxygen pathway Mother Placenta
More informationEARLY GOAL DIRECTED THERAPY : seminaires iris. Etat des lieux en Daniel De Backer
EARLY GOAL DIRECTED THERAPY : Etat des lieux en 2017 Daniel De Backer Head Dept Intensive Care, CHIREC hospitals, Belgium Professor of Intensive Care, Université Libre de Bruxelles Past-President European
More informationการอบรมว ทยาศาสตร พ นฐานทางศ ลยศาสตร เร อง นพ.ส ณฐ ต โมราก ล ภาคว ชาว ส ญญ ว ทยา คณะแพทยศาสตร โรงพยาบาลรามาธ บด มหาวทยาลยมหดล
การอบรมว ทยาศาสตร พ นฐานทางศ ลยศาสตร เร อง นพ.ส ณฐ ต โมราก ล ภาคว ชาว ส ญญ ว ทยา คณะแพทยศาสตร โรงพยาบาลรามาธ บด มหาวทยาลยมหดล Distributive shock Severe sepsis and Septic shock Anaphylactic shock Neurogenic
More informationImpedance Cardiography (ICG) Application of ICG in Intensive Care and Emergency
Impedance Cardiography (ICG) Application of ICG in Intensive Care and Emergency Aim of haemodynamic monitoring in ICU and ED Detection and therapy of insufficient organ perfusion Answers to common cardiovascular
More informationFluid Resuscitation in Critically Ill Patients with Acute Kidney Injury (AKI)
Fluid Resuscitation in Critically Ill Patients with Acute Kidney Injury (AKI) Robert W. Schrier, MD University of Colorado School of Medicine Denver, Colorado USA Prevalence of acute renal failure in Intensive
More informationWE NEED TO REDISCOVER PHYSIOLOGY!
WE NEED TO REDISCOVER PHYSIOLOGY! MERVYN SINGER BLOOMSBURY INSTITUTE OF INTENSIVE CARE MEDICINE UNIVERSITY COLLEGE LONDON, UK DECLARATIONS OF INTEREST GE Healthcare (manufacturer of Venue ultrasound/echo)
More informationWanchai Wongkornrat Cardiovascular Thoracic Surgery Siriraj Hospital Mahidol University
Wanchai Wongkornrat Cardiovascular Thoracic Surgery Siriraj Hospital Mahidol University Assess adequacy of ventilation and oxygenation Aids in establishing a diagnosis and severity of respiratory failure
More informationNorepinephrine in septic shock
Norepinephrine in septic shock Prof. Zsolt Molnár zsoltmolna@gmail.com Department of Anaesthesia and Intensive Therapy University of Szeged, Hungary A few months ago should we give it earlier? (Courtesy
More informationR Adams Cowley Founder of the R Adams Cowley Shock Trauma Center and Maryland EMS System in Baltimore, Maryland.
R Adams Cowley 1917 -- 1991 Founder of the R Adams Cowley Shock Trauma Center and Maryland EMS System in Baltimore, Maryland. ...That the primary purpose of medicine was to save lives, that every critically
More informationSepsis Combine experience and Evidence. Eran Segal, MD Director General ICU, Sheba Medical Center, Israel
Sepsis Combine experience and Evidence Eran Segal, MD Director General ICU, Sheba Medical Center, Israel The Science of Sepsis A complex and diverse clinical entity Outcome is affected by: Infecting organism
More informationThe Hemodynamic Puzzle
The Hemodynamic Puzzle SVV NIRS O 2 ER Lactate Energy Metabolism (Oxygen Consumption) (Ml/min/m 2 ) Oxygen Debt: To Pay or Not to Pay? Full Recovery Possible Delayed Repayment of O 2 Debt Oxygen Deficit
More informationECMO for Refractory Septic Shock Prof. Alain Combes
ECMO for Refractory Septic Shock Prof. Alain Combes Service de Réanimation ican, Institute of Cardiometabolism and Nutrition Hôpital Pitié-Salpêtrière, AP-HP, Paris Université Pierre et Marie Curie, Paris
More informationThe Pathophysiology of Cardiogenic Shock Knowledge Gaps & Opportunities
The Pathophysiology of Cardiogenic Shock Knowledge Gaps & Opportunities Navin K. Kapur, MD, FACC, FSCAI, FAHA Associate Professor, Department of Medicine Interventional Cardiology & Advanced Heart Failure
More informationJeopardy Tip Sheets. 12 Lead EKG Review. Leads affected. Coronary artery involved. Area of myocardium INFERIOR RCA II, III, AVF SEPTAL LAD V1 & V2
12 Lead EKG Review Jeopardy Tip Sheets Area of myocardium Coronary artery involved Leads affected INFERIOR RCA II, III, AVF SEPTAL LAD V1 & V2 ANTERIOR LAD V3 & V4 LATERAL Circumflex I, AVL, V5, V6 Normal
More informationReview Article. Interactive Physiology in Critical Illness : Pulmonary and Cardiovascular Systems. Introduction
310 Indian Deepak J Physiol Shrivastava Pharmacol 2016; 60(4) : 310 314 Indian J Physiol Pharmacol 2016; 60(4) Review Article Interactive Physiology in Critical Illness : Pulmonary and Cardiovascular Systems
More informationCritical Thinking Tip Sheets
12 Lead EKG Review Critical Thinking Tip Sheets Area of myocardium Coronary artery involved Leads affected INFERIOR RCA II, III, AVF SEPTAL LAD V1 & V2 ANTERIOR LAD V3 & V4 LATERAL Circumflex I, AVL, V5,
More informationTOPIC : Cardiogenic Shock
University of Ferrara Department of Morphology, Surgery and Experimental Medicine. Section of Anaesthesia and Intensive Care Medicine TOPIC : Cardiogenic Shock What is shock? Shock is a condition of inadequate
More informationChapter 38: Pulmonary Circulation, Pulmonary Edema, Pleural Fluid UNIT VII. Slides by Robert L. Hester, PhD
UNIT VII Chapter 38: Pulmonary Circulation, Pulmonary Edema, Pleural Fluid Slides by Robert L. Hester, PhD Objectives Describe the pulmonary circulation Describe the pulmonary blood pressures List the
More informationAPPENDIX VI HFOV Quick Guide
APPENDIX VI HFOV Quick Guide Overall goal: Maintain PH in the target range at the minimum tidal volume. This is achieved by favoring higher frequencies over lower P (amplitude). This goal is also promoted
More informationCardiovascular Physiology. Heart Physiology. Introduction. The heart. Electrophysiology of the heart
Cardiovascular Physiology Heart Physiology Introduction The cardiovascular system consists of the heart and two vascular systems, the systemic and pulmonary circulations. The heart pumps blood through
More informationUPMC Critical Care
UPMC Critical Care www.ccm.pitt.edu Shock and Monitoring Samuel A. Tisherman, MD, FACS, FCCM Professor Departments of CCM and Surgery University of Pittsburgh Shock Anaerobic metabolism Lactic acidosis
More informationINTRODUCTION The effect of CPAP works on lung mechanics to improve oxygenation (PaO 2
2 Effects of CPAP INTRODUCTION The effect of CPAP works on lung mechanics to improve oxygenation (PaO 2 ). The effect on CO 2 is only secondary to the primary process of improvement in lung volume and
More informationDr. F Javier Belda Dept. Anesthesiology and Critical Care Hospital Clinico Universitario Valencia (Spain) Pulsion MAB
State of the Art Hemodynamic Monitoring III CO, preload, lung water and ScvO2 The winning combination! Dr. F Javier Belda Dept. Anesthesiology and Critical Care Hospital Clinico Universitario Valencia
More informationShock, Monitoring Invasive Vs. Non Invasive
Shock, Monitoring Invasive Vs. Non Invasive Paula Ferrada MD Assistant Professor Trauma, Critical Care and Emergency Surgery Virginia Commonwealth University Shock Fluid Pressors Ionotrope Intervention
More informationBrief View of Calculation and Measurement of Cardiac Hemodynamics
Cronicon OPEN ACCESS EC CARDIOLOGY Review Article Brief View of Calculation and Measurement of Cardiac Hemodynamics Samah Alasrawi* Pediatric Cardiologist, Al Jalila Children Heart Center, Dubai, UAE *
More informationVeno-Venous ECMO Support. Chris Cropsey, MD Sept. 21, 2015
Veno-Venous ECMO Support Chris Cropsey, MD Sept. 21, 2015 Objectives List indications and contraindications for ECMO Describe hemodynamics and oxygenation on ECMO Discuss evidence for ECMO outcomes Identify
More informationTips & tricks on how to treat an acute heart failure patient with low cardiac output and diuretic resistance
Tips & tricks on how to treat an acute heart failure patient with low cardiac output and diuretic resistance J. Parissis Attikon University Hospital, Athens, Greece Disclosures ALARM investigator received
More informationAdmission of patient CVICU and hemodynamic monitoring
Admission of patient CVICU and hemodynamic monitoring Prepared by: Rami AL-Khatib King Fahad Medical City Pi Prince Salman Heart tcentre CVICU-RN Admission patient to CVICU Introduction All the patients
More informationChoose the grading of diastolic function in 82 yo woman
Question #1 Choose the grading of diastolic function in 82 yo woman E= 80 cm/s A= 70 cm/s LAVI < 34 ml/m 2 1= Grade 1 2= Grade 2 3= Grade 3 4= Normal 5= Indeterminate 2018 MFMER 3712003-1 Choose the grading
More informationCARDIOGENIC SHOCK. Antonio Pesenti. Università degli Studi di Milano Bicocca Azienda Ospedaliera San Gerardo Monza (MI)
CARDIOGENIC SHOCK Antonio Pesenti Università degli Studi di Milano Bicocca Azienda Ospedaliera San Gerardo Monza (MI) Primary myocardial dysfunction resulting in the inability of the heart to mantain an
More informationPositive pressure ventilation in cardiogenic shock: friend or foe?
Positive pressure ventilation in cardiogenic shock: friend or foe? ACCA Masterclass 2017 Josep Masip MD, PhD, FESC Disclosures: Novartis advisor, ThermoFisher consultant, Philips and Orion speaker fees,
More information