ACUTE LIMB ISCHEMIA Table of Contents
|
|
- Shawn Perkins
- 6 years ago
- Views:
Transcription
1 ACUTE LIMB ISCHEMIA Table of Contents PERIPHERAL ARTERIAL DISEASE (PAD)... 1 INTERMITTENT CLAUDICATION (IC)... 1 CRITICAL LIMB ISCHEMIA (CLI)... 1 ACUTE LIMB ISCHEMIA (ALI)... 2 Risk Factors...2 Associated With Femoropopliteal and Type III Disease... 3 The Most Severe Form of Peripheral Disease... 3 PRIMARY CAUSES THROMBOSIS OR EMBOLISM... 3 THROMBOSIS... 4 Most Common Sites of Thrombosis... 4 Risk Factors for Thrombosis and Embolism... 4 EMBOLISM... 5 Most Common Sites of Embolism... 5 Causes... 5 BYPASS GRAFT OCCLUSIONS... 5 POPLITEAL OR FEMORAL ARTERY ANEURYSM... 5 CLINICAL CLASSIFICATIONS OF ACUTE LIMB ISCHEMIA... 6 ISCHEMIC INJURY... 7 CONSEQUENCES MORTALITY AND LIMB LOSS... 7 Mortality Cause of Death... 8 Amputation... 8 Primary Amputation... 8 Risk of Limb Loss Increases With Duration of Ischemia... 8 SURVIVORS EXPERIENCE RAPID DETERIORATION... 9 Two-Year Outcome... 9 Exceptionally High Five-Year Mortality SURVIVORS OF ALI, AMI AND STROKE COMPARED Day Mortality Higher Than MI or Stroke Morbidity and Mortality ALI, AMI and Stroke TREATMENT Initial Therapy Anticoagulation Frail Elderly Patients with Serious Co-Morbidities Amputation or Revascularization Multiple Therapies Are The Norm SURGERY Thromboembolectomy Bypass Grafts Replacement Bypass Surgery Thrombolysis Outcome Limb Salvage and Mortality... 16
2 Complications Reperfusion Injury Compartment Syndrome THROMBOLYSIS Regional Lysis Advantages Disadvantages Clinical Outcomes Factors That Influence Amputation-Free Survival Factors Associated With Higher Mortality Complications Contraindications PLASMINOGEN ACTIVATORS Streptokinase Urokinase Prourokinase ThromboClear Tissue Plasminogen Activators (t-pa) Activase TNKase Retavase Fibrin Specificity Limitations of Plasminogen Activators Mechanism of Activity Strategies to Overcome Limitations PLASMINOGEN ACTIVATORS COMPARED Difficult to Conclude That One Agent is Superior Research is Sparse and Often Flawed Similar Range of Bleeding Complications Efficacy and Safety Retavase RELAX Trial TNKase THROMBOLYSIS AND SURGERY COMPARED Three Prospective Randomized Trials Meta-Analyses THE ROLE OF GPIIb/IIIa INHIBITORS Rationale for the Addition of Antiplatelet Agents Benefit in the Coronary Setting Potential Advantages in Acute Limb Ischemia FDA-Approved GP IIb/IIIa Inhibitors ReoPro Peripheral Experience Aggrastat Peripheral Experience Integrilin Peripheral Experience... 37
3 Comparison of GP IIb/IIIa Inhibitors PLASMINOGEN ACTIVATORS IN RESEARCH Staphylokinase Desmoteplase DIRECT FIBRINOLYTIC DRUGS Plasmin Microplasmin Fibrolase Alfimeprase Clinical Trial Results in Acute Limb Ischemia Phase III Trials in ALI NEW PHARMACEUTICAL APPROACHES UNDER INVESTIGATION TAFIa Inhibitors Dual Activity Agents Combined Antiplatelet and Anticoagulant Activity Combined Fibrinolytic and Anticoagulant Activity Proteomics THROMBOLYTIC INFUSION CATHETERS PERCUTANEOUS MECHANICAL THROMBECTOMY (PMT) FDA-Approved Devices Limitations Complications THROMBUS DISRUPTION DEVICES Helix THROMBUS ASPIRATION DEVICES Pronto Export Catheter THROMBUS DISRUPTION AND ASPIRATION DEVICES Maceration and Aspiration X-Sizer Catheter System Thrombex PMT System Endovac Rheolytic Thrombectomy AngioJet System Advantages Efficacy Adjunctive Procedures Mortality and Amputation Complications Hydrolyser Efficacy Adjunctive Procedures Mortality and Amputation Complications Oasis Efficacy and Complications... 55
4 ISOLATED THROMBOLYSIS Bacchus Trellis Efficacy Adjunctive Procedures Complications ULTRASONIC THROMBECTOMY Mechanism of Operation Safety Optimal Parameters Frequency and Power ENDOVASCULAR ULTRASOUND SYSTEMS Resolution 360 System Lysus Infusion System Acolysis System ULTRASOUND-MEDIATED MICROBUBBLE DESTRUCTION Microbubbles For Thrombus Targeted Drug and Gene Delivery SonoLysis In Acute Ischemic Stroke Thrombosed Dialysis Grafts Deep Vein Thrombosis Acute Limb Ischemia Other Commercial Microbubbles Optison Imagent/Imavist Levovist SonoVue Albunex Microbubbles in Late Clinical Trials for Myocardial Perfusion Assessment OTHER NEW PERCUTANEOUS APPROACHES CliRpath Excimer Laser COMBINATION THERAPY Debulking Power Pulse Spray (PPS) Technique Description Safety and Efficacy of Power Pulse Spray SURGERY, THROMBOLYSIS, ANGIOJET AND PPS COMPARED Outcomes Cost Thrombolysis Surgery Amputation AngioJet Power Pulse Spray (PPS) NUMBER OF PATIENTS PRESENTING WITH ALI Incidence of Acute Limb Ischemia... 74
5 Estimates Based on PAD Interventional Procedures Estimates Based on Critical Limb Ischemia National Hospital Discharge Survey Data Estimated Number of ALI Procedures Percentage of Bypass Operations Due to ALI Percentage of Amputations Due to ALI Percentage of ALI-Related Thrombolytic, Heparin and GP IIb/IIIa Infusions Conclusions Regarding Number of ALI Patients ESTIMATED NUMBER OF ACUTE LIMB ISCHEMIA PATIENTS Based on Number of PAD Patients 2000 to Assumptions and Methods Estimated Number of CLI and ALI Patients ALI Patients Expected to Decline as a Percentage of CLI Patients Factors That Could Mitigate The Decline ALI MARKET ANALYSIS METHODOLOGY ALI MARKET ESTIMATES IN NUMBER OF PROCEDURES Number of Primary Procedures per Patient Number of Patients Needing Revision Therapy Data on ALI Recurrence MARKET VALUE CONTRALATERAL ACUTE LIMB ISCHEMIA Occurrence of Contralateral PAD Data on Contralateral ALI NUMBER OF ALI CASES BY PRIMARY CAUSE THROMBOSIS AND EMBOLISM ALI Caused by Thrombosis ALI Caused by Embolism ALI PATIENTS IN EACH CLINICAL CLASSIFICATION Percentage of Patients in Each SVS-ISCVS Classification Number in Each SVS-ISCVS Classification Number of ALI Patients in Each Clinical Classification RECOMMENDED INITIAL THERAPY BY CLINICAL CLASSIFICATION PRIMARY MARKET POTENTIAL BY CLINICAL CLASSIFICATION Definitions Primary Market Potential Based on Current Recommended Initial Therapy CLINICAL CATEGORY III Percentage of Early and Late Presentation Forecast to Change THROMBOLYTIC THERAPY Primary Market Potential for Currently Approved Thrombolytics Primary Market for Isolated Thrombolysis Devices Primary Market for Devices to Speed Clot Dissolution Primary Market for New Safer Thrombolytics Primary Market for Microbubbles PMT THERAPY Primary Market Potential for Percutaneous Mechanical Thrombectomy Primary Market for New Endovascular Devices... 96
6 GP IIb/IIIa INHIBITORS Primary Market Potential for GP IIb/IIIa Therapy THROMBOEMBOLECTOMY Primary Market Potential for Surgical Thromboembolectomy REFERENCES INDEX OF TABLES AND FIGURES LIST OF COMPANIES DISCLOSURE STATEMENT CONTACT INFORMATION
Algorithm for Managing Acute Lower Extremity Ischemia. Peter A. Schneider, MD Honolulu, Hawaii
Algorithm for Managing Acute Lower Extremity Ischemia Peter A. Schneider, MD Honolulu, Hawaii Disclosure Peter A. Schneider, MD... I have the following potential conflicts of interest to report: Consulting:
More informationReducing Thrombotic Burden in Arterial Interventions. Mario Galli, MD Cardiovascular Interventional Unit S. Anna Hospital, Como, Italy
Reducing Thrombotic Burden in Arterial Interventions Mario Galli, MD Cardiovascular Interventional Unit S. Anna Hospital, Como, Italy Disclosure Speaker name: Mario Galli... I have the following potential
More information4/23/2009. September 15, 2008
The Current Treatment of Deep Venous Thrombosis: Are We Doing Enough? George H. Meier, MD Professor and Chief Division of Vascular Surgery University of Cincinnati College of Medicine Cincinnati, Ohio
More informationOptimal Utilization of Thrombolytics
April 8-9, 2011 New York LaGuardia Marriott COMPLETE MANAGEMENT OF VENOUS DISEASE Optimal Utilization of Thrombolytics Anthony J. Comerota, MD, FACS, FACC Director, Jobst Vascular Institute Adjunct Professor
More informationCatheter-Directed Thrombolysis for Acute Limb Ischemia. Hwan Jun Jae MD Seoul National University Hospital Seoul, Korea
Catheter-Directed Thrombolysis for Acute Limb Ischemia Hwan Jun Jae MD Seoul National University Hospital Seoul, Korea Disclosure Speaker name: Hwan Jun Jae... I have the following potential conflicts
More informationResident Teaching Conference 3/12/2010
Resident Teaching Conference 3/12/2010 Goals Definition and Classification of Acute Limb Ischemia Clinical Assessment of the Vascular Patient History and Physical Diagnostic Modalities Management of Acute
More informationMethods of Thrombus Fragmentation & Extraction. Methods of Thrombus Extraction
Thrombus Fragmentation and Extraction: Clinical Evidence and Practical Application No Relevant Disclosures Venita Chandra, MD Clinical Assistant Professor of Surgery Division of Stanford Medical School,
More informationENDOVASCULAR THERAPIES FOR ACUTE STROKE
ENDOVASCULAR THERAPIES FOR ACUTE STROKE Cerebral Arteriogram Cerebral Anatomy Cerebral Anatomy Brain Imaging Acute Ischemic Stroke (AIS) Therapy Main goal is to restore blood flow and improve perfusion
More informationInnovative Endovascular Approach to Pulmonary Embolism by Ultrasound Enhanced Thrombolysis. Prof. Ralf R.Kolvenbach MD,PhD,FEBVS
Innovative Endovascular Approach to Pulmonary Embolism by Ultrasound Enhanced Thrombolysis Prof. Ralf R.Kolvenbach MD,PhD,FEBVS Catheter-based thrombolysis Local administration of lytic agent Higher local
More informationIntended Learning Outcomes
2011 Acute Limb Ischemia Definition, Etiology & Pathophysiology Clinical Evaluation Management Ali SABBOUR Prof. of Vascular Surgery, Ain Shams University Acute Limb Ischemia Intended Learning Outcomes
More informationCRITICAL LIMB ISCHEMIA UNITED STATES EPIDEMIOLOGY TABLE OF CONTENTS
CRITICAL LIMB ISCHEMIA UNITED STATES EPIDEMIOLOGY TABLE OF CONTENTS CRITICAL LIMB ISCHEMIA... 1 CONCLUSION... 9 U.S. CRITICAL LIMB ISCHEMIA PREVALENCE... 9 MARKET OPPORTUNITY ENDOVASCULAR... 9 MARKET OPPORTUNITY
More informationDethrombosis of the Lower Extremities: Pharmacologic and Mechanical Techniques
Shammas.qxd 5/1/06 11:42 AM Page 235 CL I N I CA L RE V I E W Dethrombosis of the Lower Extremities: Pharmacologic and Mechanical Techniques Nicholas W. Shammas, MD, MS Abstract Thrombus is widely present
More informationAggressive endovascular management of ilio-femoral DVT. thrombotic syndrome. is the key in preventing post
CACVS 2017 Aggressive endovascular management of ilio-femoral DVT is the key in preventing post thrombotic syndrome ALI AMIN MD, FACS,FACC, RVT CHIEF OF ENDOVASCULAR INTERVENTIONS READING HEALTH SYSTEM
More informationAcute and Subacute Ischemia of Lower Limb Can Mechanical Debulking Replace Surgery and Thrombolysis?
Acute and Subacute Ischemia of Lower Limb Can Mechanical Debulking Replace Surgery and Thrombolysis? Miroslav Bulvas King s Vineyards Hospital 3 rd School of Medicine, Charles University, Prague Disclosure
More informationSAFETY AND EFFECTIVENESS OF ENDOVASCULAR REVASCULARIZATION FOR PERIPHERAL ARTERIAL OCCLUSIONS
SAFETY AND EFFECTIVENESS OF ENDOVASCULAR REVASCULARIZATION FOR PERIPHERAL ARTERIAL OCCLUSIONS LIBBY WATCH, MD MIAMI VASCULAR SPECIALISTS MIAMI CARDIAC & VASCULAR INSTITUTE FINANCIAL DISCLOSURES None 2
More informationThrombolysis in Critical Limb Ischemia Frank J. Arena, MD, FACC, FSCAI
Thrombolysis in Critical Limb Ischemia Frank J. Arena, MD, FACC, FSCAI Chairman, Dept. of Cardiology Tulane University-Lakeview Campus Covington, La. Disclosures Sadly-None What are the Goals of Thrombolysis
More informationSTEMI update. Vijay Krishnamoorthy M.D. Interventional Cardiology
STEMI update Vijay Krishnamoorthy M.D. Interventional Cardiology OVERVIEW Current Standard of Care in Management of STEMI Update in management of STEMI Pre-Cath Lab In the ED/Office/EMS. Cath Lab Post
More informationEKOS. Interventional Vascular 3 February, Imagine where we can go.
EKOS Interventional Vascular 3 February, 2015 Imagine where we can go. Forward-looking statement This presentation and information communicated verbally to you may contain certain projections and other
More informationPEARL Registry Update Overview Venous Arterial AV Access
PEARL Registry Update Overview Venous Arterial AV Access PEARL Registry Overview (as of 10 Sep12*) Overview Venous Arterial AV Access HOME Topic Data Support Comments Study Design Prospective, non-randomized,
More informationPharmaco-mechanical techniques stand alone procedures? Peter Neglén, MD, PhD SP Vascular Center Limassol Cyprus
Pharmaco-mechanical techniques stand alone procedures? Peter Neglén, MD, PhD SP Vascular Center Limassol Cyprus Faculty Disclosure Peter Neglén, M.D., Ph.D Stockholder/Founder of Veniti, Inc. Member, Medical
More informationUltrasound-assisted catheter-directed thrombolysis: Does it really work? The BERNUTIFUL trial
Ultrasound-assisted catheter-directed thrombolysis: Does it really work? The BERNUTIFUL trial Rolf P. Engelberger Division of Angiology CHUV, Lausanne & Inselspital, Bern Switzerland Disclosure Speaker
More informationMechanical thrombectomy in peripheral interventions: A multitask and effective tool in a widening scenario. Current evidence and technical tips.
Mechanical thrombectomy in peripheral interventions: A multitask and effective tool in a widening scenario. Current evidence and technical tips. Dr. Bruno Freitas, Prof., MD Department of Interventional
More informationWhen the learner has completed this module, she/he will be able to:
Thrombolytics and Myocardial Infarction WWW.RN.ORG Reviewed September 2017, Expires September 2019 Provider Information and Specifics available on our Website Unauthorized Distribution Prohibited 2017
More informationAcoustic Pulse Thrombolysis Treatment
Acoustic Pulse Thrombolysis Treatment BTGVascular.com SETTING THE STANDARD FOR VASCULAR THERAPIES Quickly & safely dissolve thrombus with the EKOS System. The Acoustic Pulse Difference Acoustic Pulse Thrombolysis
More informationAcute arterial embolism
Acute arterial embolism Definition Thrombus come from heart or blood vessel or other embolus such as tumor,air gas or fat flow with blood stream and occlude distal limb or visceral arteries which causes
More informationCatheter-directed thrombolysis versus percutaneous mechanical thrombectomy in the management of acute limb ischemia: a single center review
Muli Jogi et al. CVIR Endovascular (2018) 1:35 https://doi.org/10.1186/s42155-018-0041-1 CVIR Endovascular ORIGINAL ARTICLE Catheter-directed thrombolysis versus percutaneous mechanical thrombectomy in
More informationWHO YOU GONNA CALL? CLOT-BUSTERS!
WHO YOU GONNA CALL? CLOT-BUSTERS! Jayer Chung MD, MSc Assistant Professor Division of Vascular Surgery and Endovascular Therapy Michael E DeBakey Department of Surgery Baylor College of Medicine Annual
More informationENHANCING YOUR OPTIONS
ANGIOJET ULTRA Thrombectomy System ENHANCING YOUR OPTIONS FOR RESTORING FLOW When you need the versatility and power to restore flow Refined from experience in over 700,000 cases worldwide, today s AngioJet
More informationPeripheral Vascular Disease
Peripheral artery disease (PAD) results from the buildup of plaque (atherosclerosis) in the arteries of the legs. For people with PAD, symptoms may be mild, requiring no treatment except modification of
More informationSurgical approach for DVT. Division of Vascular Surgery Department of Surgery Seoul National University College of Medicine
Surgical approach for DVT Seung-Kee Min Division of Vascular Surgery Department of Surgery Seoul National University College of Medicine Treatment Options for Venous Thrombosis Unfractionated heparin &
More informationAcute Limb Ischemia. Management of Common Peripheral Vascular Disease. Etiology. Peripheral Vascular disease 11/10/2014
Acute Limb Ischemia Management of Common Peripheral Vascular Disease October 7, 2014 นพ.ณรงช ย ว องกลก จศ ลป Diplomate, Thai Board of Surgery. Diplomate, Thai Subspecialty Board of Vascular Surgery. Diplomate,
More informationTHERE IS NO ROLE FOR SURGICAL THERAPY FOR DVT
THERE IS NO ROLE FOR SURGICAL THERAPY FOR DVT Tara D. Balint, MD FACS Sentara RMH Thursday, June 14, 2018 1 Objectives of treatment for DVT Prevent death from PE Prevent recurrent VTE Prevent post-thrombotic
More informationAspirex for Upper and Lower Extremity DVT
Aspirex for Upper and Lower Extremity DVT Steven Kum MD Vascular & Endovascular Surgeon Director of Vascular Service Changi General Hospital Singapore Disclosure Speaker name:... I have the following potential
More informationCHALLENGING ILIAC ACCESSES AND THROMBOSIS PREVENTION
CHALLENGING ILIAC ACCESSES AND THROMBOSIS PREVENTION ARMANDO MANSILHA MD, PhD, FEBVS UNIVERSITY HOSPITAL - PORTO Disclosure of Interest Speaker name: ARMANDO MANSILHA I have the following potential conflicts
More informationMechanical Thrombectomy systems: The cost effective way to manage clot? Dr Stephen D SOUZA Dr Bella Huasen Interventional Radiology Royal Preston.
Mechanical Thrombectomy systems: The cost effective way to manage clot? Dr Stephen D SOUZA Dr Bella Huasen Interventional Radiology Royal Preston. UK Disclosure Speaker name: Stephen D Souza I have the
More informationMechanical Thrombectomy Devices. Thomas M. Vesely, MD Vascular Access Services, LLC Saint Louis, Missouri
Mechanical Thrombectomy Devices Thomas M. Vesely, MD Vascular Access Services, LLC Saint Louis, Missouri No conflicts of interest relevant to thrombolysis / mechanical thrombectomy Number and Type of Hemodialysis
More informationTurbo-Power. Laser atherectomy catheter. The standard. for ISR
Turbo-Power Laser atherectomy catheter The standard for ISR Vaporize the ISR challenge In-stent restenosis (ISR) Chance of recurring 7 115,000 + /year (U.S.) 1-6 Repeated narrowing of the arteries after
More informationPercutaneous Mechanical Thrombectomy for Acute Iliofemoral DVT with the Aspirex Catheter: The Dijon Experience
JFICV 2018, Beaune Percutaneous Mechanical Thrombectomy for Acute Iliofemoral DVT with the Aspirex Catheter: The Dijon Experience Prof. Romaric LOFFROY, MD, PhD, FCIRSE Chief, Department of Vascular and
More informationVenous interventions in DVT
Venous interventions in DVT Sriram Narayanan Chief of Vascular and Endovascular Surgery, Tan Tock Seng Hospital A/Prof of Surgery, National University of Singapore ANTI-COAGULATION LMWH Warfarin x 6m Acute
More informationThe hallmark of percutaneous thrombus management
Treating Venous Thromboembolism Without Lytic Medications What the present and the near future will bring in terms of techniques and devices to remove venous thrombus. BY CONSTANTINO S. PEÑA, MD; RIPAL
More informationOutcomes Of Combined Rheolytic And Rotational Mechanical Thrombectomy For Total Access Circuit Thrombosis In Hemodialysis Patients
Outcomes Of Combined Rheolytic And Rotational Mechanical Thrombectomy For Total Access Circuit Thrombosis In Hemodialysis Patients Nicholas Petruzzi, MD Raphael Cohen, MD Mark Mantell, MD Timothy W. Clark,
More informationWhen and how to use distal protection devices for lower extremity revascularization. Peter A. Schneider, MD Kaiser Foundation Hospital, Honolulu
When and how to use distal protection devices for lower extremity revascularization Peter A. Schneider, MD Kaiser Foundation Hospital, Honolulu Disclosure Peter A. Schneider Potential conflicts of interest
More informationAcute coronary syndromes
Acute coronary syndromes 1 Acute coronary syndromes Acute coronary syndromes results primarily from diminished myocardial blood flow secondary to an occlusive or partially occlusive coronary artery thrombus.
More informationIntroduction. Risk factors of PVD 5/8/2017
PATHOPHYSIOLOGY AND CLINICAL FEATURES OF PERIPHERAL VASCULAR DISEASE Dr. Muhamad Zabidi Ahmad Radiologist and Section Chief, Radiology, Oncology and Nuclear Medicine Section, Advanced Medical and Dental
More informationGuideline for STEMI. Reperfusion at a PCI-Capable Hospital
MANSOURA. 2015 Guideline for STEMI Reperfusion at a PCI-Capable Hospital Mahmoud Yossof MANSOURA 2015 Reperfusion Therapy for Patients with STEMI *Patients with cardiogenic shock or severe heart failure
More informationRecurrent Thrombosis in a Case of Coronary Ectasia with Large Thrombus Burden Successfully Treated by Adjunctive Warfarin Therapy
Case Report Acta Cardiol Sin 2013;29:462 466 Recurrent Thrombosis in a Case of Coronary Ectasia with Large Thrombus Burden Successfully Treated by Adjunctive Warfarin Therapy Hung-Hao Lee, 1 Tsung-Hsien
More information2019 ABBOTT REIMBURSEMENT GUIDE CMS Physician Fee Schedule
ABBOTT REIMBURSEMENT GUIDE CMS Physician Fee Schedule This document and the information contained herein is for general information purposes only and is not intended and does not constitute legal, reimbursement,
More informationSinus Venous Thrombosis
Sinus Venous Thrombosis Joseph J Gemmete, MD FACR, FSIR, FAHA Professor Departments of Radiology and Neurosurgery University of Michigan Hospitals Ann Arbor, MI Outline Introduction Medical Treatment Options
More informationCatheter Interventions for pulmonary embolism:
Catheter Interventions for pulmonary embolism: From Directed tpa Drips to Suction Thrombectomy Efthymios Avgerinos, MD Associate Professor of Surgery Division of Vascular Surgery University of Pittsburgh
More informationTechnique de recanalisation: mon expérience avec Aspirex
JFICV 2017, Deauville Thrombose veineuse profonde aiguë en 2017 Technique de recanalisation: mon expérience avec Aspirex Romaric LOFFROY Département de Radiologie Diagnostique et Thérapeutique CHU Hôpital
More informationIndex. Hematol Oncol Clin N Am 19 (2005) Note: Page numbers of article titles are in boldface type.
Hematol Oncol Clin N Am 19 (2005) 203 208 Index Note: Page numbers of article titles are in boldface type. A Abciximab, as an antiplatelet agent, 93 94 Acute coronary syndromes, use of antiplatelet drugs
More informationStraub Endovascular System &
Straub Endovascular System & S t r a u b E n d o v a s c u l a r To o l s Straub Endovascular System Effective debulking in occluded arteries and veins Effective debulking in many indications Rotarex
More informationInnovative Endovascular Approach to Pulmonary Embolism by Ultrasound Enhanced Thrombolysis. Prof. Ralf R.Kolvenbach MD,PhD,FEBVS
Innovative Endovascular Approach to Pulmonary Embolism by Ultrasound Enhanced Thrombolysis Prof. Ralf R.Kolvenbach MD,PhD,FEBVS Conflict of Interest BTG Standard PE therapy ANTICOAGULATION (AC) HEPARIN
More informationPercutaneously Inserted AngioVac Suction Thrombectomy for the Treatment of Filter-Related. Iliocaval Thrombosis
Percutaneously Inserted AngioVac Suction Thrombectomy for the Treatment of Filter-Related Iliocaval Thrombosis Faiz D. Francis, DO; Gianvito Salerno, MD; Sabbah D. Butty, MD Abstract In the setting of
More information(For items 1-12, each question specifies mark one or mark all that apply.)
Form 121 - Report of Cardiovascular Outcome Ver. 9.2 COMMENTS -Affix label here- Member ID: - - To be completed by Physician Adjudicator Date Completed: - - (M/D/Y) Adjudicator Code: - Central Case No.:
More informationTom Eisele, Benedikt M. Muenz, and Grigorios Korosoglou. Department of Cardiology & Vascular Medicine, GRN Hospital Weinheim, Weinheim, Germany
Case Reports in Vascular Medicine Volume 2016, Article ID 7376457, 4 pages http://dx.doi.org/10.1155/2016/7376457 Case Report Successful Endovascular Repair of an Iatrogenic Perforation of the Superficial
More informationPopliteal Aneurysm: When is surgical therapy indicated? PROF. GRZEGORZ OSZKINIS
Popliteal Aneurysm: When is surgical therapy indicated? PROF. GRZEGORZ OSZKINIS Asymptomatic mass - 38-40%will develop symptoms at a rate of 14%/yr Intermittent claudic ation (chronic ischemia) - 25%-40%
More informationDevice Evolution. Atherectomy: Where Do We Stand After 12 Years Since FDA Clearance. Where Do We Stand? 4/18/2015
Disclosure Statement of Financial Interest Atherectomy: Where Do We Stand After 12 Years Since FDA Clearance Within the past 12 months, I or my spouse/partner have had a financial interest/arrangement
More informationInterventional Treatment VTE: Radiologic Approach
Interventional Treatment VTE: Radiologic Approach Hae Giu Lee, MD Professor, Dept of Radiology Seoul St. Mary s Hospital The Catholic University of Korea Introduction Incidence High incidence: 250,000-1,000,000/year
More informationANTITHROMBOTIC/ANTICOAGULANT DRUGS: TECHNOLOGIES AND GLOBAL MARKETS
ANTITHROMBOTIC/ANTICOAGULANT DRUGS: TECHNOLOGIES AND GLOBAL MARKETS PHM119B September 2016 Anuj Pathak Project Analyst ISBN: 1-62296-345-8 BCC Research 49 Walnut Park, Building 2 Wellesley, MA 02481 USA
More informationRotarex mechanical debulking: The Leipzig experience in patients
Rotarex mechanical debulking: The Leipzig experience in 1.200+ patients Dierk Scheinert, MD Division of Interventional Angiology University-Hospital Leipzig, Germany Disclosure Speaker name: Dierk Scheinert
More informationComplications of Thrombolysis
Complications of Thrombolysis David H. Jang, M.D. Lewis S. Nelson, M.D. Case Summary: An 88 year-old man with a past medical history of hypertension and paroxysmal atrial fibrillation presented to the
More informationPACT module High risk surgical patient. Intensive Care Training Program Radboud University Medical Centre Nijmegen
PACT module High risk surgical patient Intensive Care Training Program Radboud University Medical Centre Nijmegen Intravascular volume effect of Ringer s lactate Double-tracer BV measurement Blood 1097
More information9 : , % % Tel : Tel : 5,6 7,8
9 : 491-497, 2000 1 1 2 1 1 1 1 1 73 5 60% 44% 11 25 55% 6 11 90% 9 10 10% 1 10 14% 1 7 9.7% 6 62 9.1% 5 55 29 30 10 33% 40% 4 10 100% 4 4 14 20 MNMS 1 2 1 III 1 2 4 1 9 : 491-497, 2000 1 Tel : 0764-24-1531
More informationEndovascular Should Be Considered First Line Therapy
Revascularization of Patients with Critical Limb Ischemia Endovascular Should Be Considered First Line Therapy Michael Conte David Dawson David L. Dawson, MD Revised Presentation Title A Selective Approach
More informationPEARL REGISTRY Post Market Registry
PEARL REGISTRY Post Market Registry Real World Use of the AngioJet Thrombectomy System in the Peripheral Vascular System PI-315422-AA JUN2015 Objectives AngioJet Action Enrollment General Indications &
More informationLIBERTY 360 Study. 15-Jun-2018 Data 1. Olinic Dm, et al. Int Angiol. 2018;37:
LIBERTY 360 Study LIBERTY is a prospective, observational, multi-center study to evaluate procedural and long-term clinical and economic outcomes of endovascular device interventions in patients with symptomatic
More informationThe restoration of coronary flow after an
Pharmacological Reperfusion in Acute Myicardial Infarction after ASSENT 3 and GUSTO V [81] DANIEL FERREIRA, MD, FESC Serviço de Cardiologia, Hospital Fernando Fonseca, Amadora, Portugal Rev Port Cardiol
More informationSimultaneous Acute ST Elevation Myocardial Infarction And Acute Left Subclavian Artery Thrombosis
Simultaneous Acute ST Elevation Myocardial Infarction And Acute Left Subclavian Artery Thrombosis Chee Yang CHIN, MBChB, MRCP(UK) C.W.L. Chin, P.T.L. Chiam, R.S. Tan National Heart Centre Singapore 26
More informationThe hallmark of percutaneous thrombus management
Treating Venous Thromboembolism Without Lytic Medications What the present and the near future will bring in terms of techniques and devices to remove venous thrombus. BY CONSTANTINO S. PEÑA, MD; RIPAL
More informationWhat is New in Acute Pulmonary Embolism? Interventional Treatment. Prof. Nils Kucher University Hospital Bern Switzerland
What is New in Acute Pulmonary Embolism? Interventional Treatment Prof. Nils Kucher University Hospital Bern Switzerland nils.kucher@insel.ch Disclosure of Interest Dr. Kucher received research grants
More informationThrombolysis of Acute Arterial Occlusion with rt-pa
Thrombolysis of Acute Arterial Occlusion with rt-pa Mehmet KURTOÐLU*, Volkan GRAN T**, Ahmet NECEFL *, Metin KURTOÐLU**, Recep GÜLOÐLU* * Department of General Surgery, stanbul Faculty of Medicine, **
More informationWHI Form Report of Cardiovascular Outcome Ver (For items 1-11, each question specifies mark one or mark all that apply.
WHI Form - Report of Cardiovascular Outcome Ver. 6. COMMENTS To be completed by Physician Adjudicator Date Completed: - - (M/D/Y) Adjudicator Code: OMB# 095-044 Exp: 4/06 -Affix label here- Clinical Center/ID:
More informationOutcomes of limb and life in patients with acute lower limb ischemia presenting before and after the golden six hours
International Journal of Advances in Medicine Nekkanti MK et al. Int J Adv Med. 218 Aug;5(4):788-797 http://www.ijmedicine.com pissn 2349-3925 eissn 2349-3933 Original Research Article DOI: http://dx.doi.org/1.1823/2349-3933.ijam2182498
More informationWilliam A. Gray MD System Chief of Cardiovascular Services, Main Line Health President, Lankenau Heart Institute Wynnewood, PA USA
William A. Gray MD System Chief of Cardiovascular Services, President, Wynnewood, PA USA Why atherectomy? Calcification is the norm not the exception Most trials do not include heavy calcification There
More informationUse of EKOS Catheter in the management of Venous Mr. Manoj Niverthi, Mr. Sarang Pujari, and Ms. Nupur Dandavate, The GTF Group
Use of EKOS Catheter in the management of Venous Thromboembolism @ Mr. Manoj Niverthi, Mr. Sarang Pujari, and Ms. Nupur Dandavate, The GTF Group Introduction Georgia Thrombosis Forum (GTF, www.gtfonline.net)
More informationFacilitated Percutaneous Coronary Intervention in Acute Myocardial Infarction. Is it beneficial to patients?
Facilitated Percutaneous Coronary Intervention in Acute Myocardial Infarction Is it beneficial to patients? Seung-Jea Tahk, MD. PhD. Suwon, Korea Facilitated PCI.. background Degree of coronary flow at
More informationFastTest. You ve read the book now test yourself
FastTest You ve read the book...... now test yourself To ensure you have learned the key points that will improve your patient care, read the authors questions below. The answers will refer you back to
More informationKorea University Guro Hospital, Seoul, Korea * Chonnam National University Hospital, Gwangju, Korea
Left Main Disease versus Non Left Main Disease in Acute Myocardial Infarction Patients in Real world Clinical Practice : Lessons from Korea Acute Myocardial Infarction Registry (KAMIR) Seung-Woon Rha*,
More informationQuinn Capers, IV, MD
Heart Attacks Mended Hearts Presentation, January, 2017 Quinn Capers, IV, MD Associate Professor of Medicine (Cardiovascular Medicine) Director, Transradial Coronary Interventions Division of Cardiovascular
More informationMechanical thrombectomy in acute thrombosis of dialysis fistulas: a multi-center study
Mechanical thrombectomy in acute thrombosis of dialysis fistulas: a multi-center study Clément Marcelin 1 Y Le Bras 1, MD, F. Petitpierre 1, MD, N. Grenier 1, MD PHD, J V D Berg MD PHD 3, B Huasen 2, MD
More informationIndex. C Capillary telangiectasia, intracerebral hemorrhage in, 295 Carbon monoxide, formation of, in intracerebral hemorrhage, edema due to,
Neurosurg Clin N Am 13 (2002) 395 399 Index Note: Page numbers of article titles are in boldface type. A Age factors, in intracerebral hemorrhage outcome, 344 Albumin, for intracerebral hemorrhage, 336
More informationRotarex mechanical thrombectomythe first line option for thrombotic occlusions?
Rotarex mechanical thrombectomythe first line option for thrombotic occlusions? Dierk Scheinert, MD Division of Interventional Angiology University Hospital Leipzig, Germany Disclosure Advisory Board /Consultant:
More informationNATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE
NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE INTERVENTIONAL PROCEDURES PROGRAMME Interventional procedure overview of Interventional procedure overview of ultrasound-enhanced, catheterdirected thrombolysis
More informationPRISM Trial. Retrospective Case Review of Technical Success Using the Penumbra and Indigo Systems for Mechanical Thrombectomy in the Periphery
PRISM Trial Retrospective Case Review of Technical Success Using the Penumbra and Indigo Systems for Mechanical Thrombectomy in the Periphery George L. Adams, MD, MHS, FACC, FSCAI Clinical Associate Professor
More informationCatheter-Directed Thrombolytic Therapy in Peripheral Artery Occlusions: Combining Reteplase and Abciximab
Peter Drescher 1,2 James McGuckin 3 William S. Rilling 1 Martin R. Crain 1,2 Received July 5, 2002; accepted after revision October 1, 2002. 1 Department of Radiology, Medical College of Wisconsin, 9200
More informationChallenging Case of Pulse Infusion Thrombolysis Using a Unique Pump System for a Patient With Deep Vein Thrombosis: A Case Report
J Cardiol 2002 Feb; 39 2 : 115 119 Challenging Case of Pulse Infusion Thrombolysis Using a Unique Pump System for a Patient With Deep Vein Thrombosis: A Case Report MD Seiji Taro Katsuo Yasushi Fumiyuki
More information9/7/2018. Disclosures. CV and Limb Events in PAD. Challenges to Revascularization. Challenges. Answering the Challenge
Disclosures State-of-the-Art Endovascular Lower Extremity Revascularization Promotional Speaker Jansen Pharmaceutical Promotional Speaker Amgen Pharmaceutical C. Michael Brown, MD, FACC al Cardiology Associate
More informationMeissner MH, Gloviczki P, Comerota AJ, Dalsing MC, Eklof BG, Gillespie DL, et al. J Vasc Surg. 2012;55:
Early thrombus removal strategies for acute deep venous thrombosis: Clinical Practice Guidelines of the Society for Vascular Surgery and the American Venous Forum Meissner MH, Gloviczki P, Comerota AJ,
More informationAngioJet Rheolytic Thrombectomy During Rescue PCI for Failed Thrombolysis: A Single-Center Experience
AngioJet Rheolytic Thrombectomy During Rescue PCI for Failed Thrombolysis: A Single-Center Experience Dimitri A. Sherev, MD, David M. Shavelle, MD, Murrad Abdelkarim, MD, Thomas Shook, MD, Guy S. Mayeda,
More informationNot all Leg DVT s are the Same: Which Patients Benefit from Interventional Therapy? Case 1:
12/16/2015 Not all Leg DVT s are the Same: Which Patients Benefit from Interventional Therapy? Constantino S.Peña, FSIR, FSCCT, FAHA Interventional Radiologist Medical Director, Vascular Imaging Miami
More informationRevived indications for thrombus aspiration during primary PCI: Unanswered questions after TAPAS
Revived indications for thrombus aspiration during primary PCI: Unanswered questions after TAPAS Gregg W. Stone MD Columbia University Medical Center Cardiovascular Research Foundation Disclosures Gregg
More informationISR-treatment The Leipzig experience with purely mechanical debulking. Sven Bräunlich Department for Angiology University-Hospital Leipzig, Germany
ISR-treatment The Leipzig experience with purely mechanical debulking Sven Bräunlich Department for Angiology University-Hospital Leipzig, Germany Disclosure Speaker name: Sven Bräunlich I have the following
More informationCY2017 Hospital Outpatient: Vascular Procedure APCs and Complexity Adjustments
CY2017 Hospital Outpatient: Vascular Procedure APCs and Complexity Adjustments Comprehensive Ambulatory Payment Classifications (c-apcs) In CY2015 and in an effort to help pay providers for quality, not
More informationNATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE
NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE INTERVENTIONAL PROCEDURES PROGRAMME Interventional procedure overview of Interventional procedure overview of ultrasound-enhanced, catheterdirected thrombolysis
More informationAcute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis (ATTRACT Trial)
Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis (ATTRACT Trial) N Engl J Med. Volume 377(23):2240-2252. December 7, 2017 Wednesday, July 11, 2018, 1:00pm ET Guest
More informationHEART AND SOUL STUDY OUTCOME EVENT - MORBIDITY REVIEW FORM
REVIEW DATE REVIEWER'S ID HEART AND SOUL STUDY OUTCOME EVENT - MORBIDITY REVIEW FORM : DISCHARGE DATE: RECORDS FROM: Hospitalization ER Please check all that may apply: Myocardial Infarction Pages 2, 3,
More informationShould We Be More Aggressive in the Treatment of Acute DVT?
DISCLOSURES Consultant Penumbra, Inc. UCSF Vascular Surgery Symposium April 6, 2017 K. Pallav Kolli, MD Assistant Professor of Clinical Radiology University of California, San Francisco 17 yo male, DVT
More informationInterventional Management of Acute Pulmonary Embolism
Interventional Management of Acute Pulmonary Embolism Prof. Nils Kucher Angiology & Cardiology University Hospital Bern Inselspital nils.kucher@insel.ch DECLARATION OF CONFLICT OF INTEREST Consultant to
More information3-year results of the OLIVE registry:
3-year results of the OLIVE registry: A prospective multicenter study in patients with critical limb ischemia Osamu Iida, MD Kansai Rosai Hospital Cardiovascular Center Amagasaki, Hyogo, Japan Disclosure
More information