CARDIAC AND CORONARY ARTERY ANATOMY NO DISCLOSURES. Axial Anatomy of Heart. Axial Anatomy of Heart. Axial Anatomy of Heart
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1 CARDIAC AND CORONARY ARTERY ANATOMY NO DISCLOSURES NASCI MEETING, ORLANDO FLORIDA 2009 KOSTAKI G. BIS, MD, FACR DEPARTMENT OF RADIOLOGY WILLIAM BEAUMONT HOSPITAL Royal Oak, Michigan OBJECTIVES CARDIAC ANATOMY- VARIOUS IMAGING PLANES NORMAL, VARIANT and SOME ANOMALOUS ANATOMY OF CORONARY ARTERIES AND SUBJACENT VEINS IMPORTANT FOR CORRECT IMAGE INTERPRETATION AND PATIENT CARE ASCENDING AORTA SVC R- SUPERIOR PULMONARY VEIN MAIN PULMONARY ARTERY BIFURC N L- SUPERIOR PULMONARY VEIN DESCENDING AORTA PULMONARY VALVE LEFT ATRIAL APPENDAGE LAD INFLOW L- SUPERIOR PULMONARY VEIN 1
2 SVC INFLOW INFLOW R- SUPERIOR PULMONARY VEIN RVOT L-MAIN RIGHT ATRIAL APPENDAGE CEPHALAD INTERATRIAL SEPTUM L- MAIN ORIGIN RCA NON-CORONARY CUSP LAD LCx SA-NODE BRANCH INFLOW L- INFERIOR PULMONARY VEIN AORTIC VALVE INFLOW R-INFERIOR PULMONARY VEIN LVOT MITRAL VALVE 2
3 INTERVENTRICULAR SEPTUM RCA LAD LCx INTERATRIAL SEPTUM RV RA LA LV ANTEROLATERAL PAPILLARY MUSCLE TRICUSPID VALVE PLANE IVC INFLOW INFLOW- CORONARY SINUS CORONARY SINUS DISTAL RCA POSTEROMEDIAL PAPILLARY MUSCLES SUPRAHEPATIC IVC 3
4 -MRI PDA IMAGING PLANES (SET-UP) RAO CARDIAC ANATOMY-(4D MIPs) (VERTICAL LONG AXIS-RAO) RAO LAO CARDIAC AND CORONARY ARTERY ANATOMY-(3D (3D-MIPs) (VERTICAL LONG AXIS-RAO) CARDIAC ANATOMY-(CINE MRI) (VERTICAL LONG AXIS-RAO) 4
5 CARDIAC ANATOMY-(4D (4D-MIPs) (HORIZONTAL LONG AXIS, 4 CHAMBER) CARDIAC AND CORONARY ARTERY ANATOMY-(3D (3D-MIPs) (HORIZONTAL LONG AXIS) HLA CARDIAC ANATOMY-(CINE MRI) (HORIZONTAL LONG AXIS) CARDIAC ANATOMY-(CINE MRI) (HORIZONTAL LONG AXIS) CARDIAC ANATOMY-(4D (4D-MIPs) (SHORT AXIS-LAO) CARDIAC AND CORONARY ARTERY ANATOMY-(3D (3D-MIPs) (SHORT AXIS-LAO) LAO 5
6 CARDIAC ANATOMY-(CINE MRI) (SHORT AXIS-LAO) 17-MYOCARDIAL SEGMENT MODEL Above schematic is for RCA dominance. Note: With left dominance, LCx supplies the inferior septum and inferior distributions BASE CARDIAC ANATOMY-(CINE MRI) (INLET-OUTLET, 3-CHAMBER, 3 PARASTERNAL LONG AXIS ) MIDDLE APEX ADDITIONAL VIEWS-(CINE MRI) CORONARY DOMINANCE Determined by blood supply to inferior wall PDA, PLB and AV-node branches help define dominance LVOT RVOT AORTIC ROOT Direct coronal Oblique coronal Oblique axial 6
7 RIGHT DOMINANCE (80-85%) 85%) RCA gives rise to PDA, PLB and AV-node branches PDA supplies inferior septum PLB supplies inferior wall DOMINANT RCA ANATOMY- ANTERIOR SCHEMATIC DOMINANT RCA ANATOMY RCA ANATOMY RCA proximal From ostium to one half the distance to the acute margin of the heart. RCA middle RCA from above segment to the acute margin of heart. RCA distal - From the acute margin to the origin of the PDA. Report of the Ad-Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery. Circulation 1975; 51:5-40. CONUS BRANCH VARIATIONS CONUS BRANCH FROM LAD 50% Conus Branch Supplies RVOT 50% 7
8 SA-NODE BRANCH VARIATIONS RV (ACUTE) MARGINAL BRANCHES SUPPLY ANTERIOR RV 55% FROM RCA 45% FROM LCx PDA and PLB VARIATION- RCA DOMINANCE AV-NODE BRANCH - RIGHT DOMINANCE SINGLE PDA and PLB HIGH PDA TAKE-OFF DUAL PDA and PLB PDA Usually distal to PDA LEFT DOMINANCE (15-20%) PDA and PLB arise from LCx and supply inferior wall and inferior septum AV-Node branch usually distal to PDA LAO SCHEMATIC- DOMINANT LEFT CORONARY ANATOMY 8
9 DOMINANT LCx ANATOMY DOMINANT LCx ANATOMY AVGA= AV-groove artery of LCx DOMINANT LCx ANATOMY- Dual PDA CO-DOMINANCE (5%) PDA ARISES FROM RCA PLB ARISES FROM LCx LEFT MAIN BIFURCATION LAO SCHEMATIC- DOMINANT LEFT CORONARY ANATOMY LM mm 9
10 LEFT MAIN TRIFURCATION- RAMUS INTERMEDIUS BRANCH VARIATION RAMUS INTERMEDIUS BRANCH VARIATION Single RI RI DISTRIBUTION- AS DIAGONAL OR OBTUSE MARGINAL Dual RI MOST COMMON LCA VARIATION LAD ANATOMY LAD proximal Proximal to and including origin of the first major septal perforator. LAD middle Distal to origin of first major septal perforator and extending to point where the LAD forms an angle (RAO view). This is often, but not always, close to the origin of the second diagonal. If this angle or diagonal is not identifiable, this segment ends one half the distance from the first major septal perforator to the apex. LAD apical Beginning at the end of the previous segment and extending to or beyond the apex. Report of the Ad-Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery. Circulation 1975; 51:5-40. RAO LAD ANATOMY SEPTAL PERFORATOR BRANCH VARIATION DIAGONAL BRANCH ANATOMY NUMBERED IN SEQUENCE S1, S2, S3.. SUPPLY VENTRICULAR SEPTUM NUMBERED IN SEQUENCE D1, D2, D3.. SUPPLY ANTERIOR WALL 10
11 LCX ANATOMY NON-DOMINANT LCx ANATOMY LCx proximal From it s origin off LCA to and including origin of obtuse marginal. LCx distal The LCx distal to the origin of the obtuse marginal and running along or close to left (posterior) AV groove. Report of the Ad-Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery. Circulation 1975; 51:5-40. AXIAL-ANTERIOR ANTERIOR LAO DOMINANT LCx ANATOMY Cardiac Veins OBTUSE MARGINAL BRANCHES NUMBERED IN SEQUENCE : OM1, OM2, OM3.. SUPPLY LATERAL WALL Cardiac Veins PDA and MIDDLE CARDIAC VEIN 11
12 SMALL CARDIAC VEIN ANTERIOR INTERVENTRICULAR VEIN AND GREAT CARDIAC VEIN AIV AIV AIV GCV GCV CAUDAL-TO TO-CRANIAL ACQUISITION TRIPLE R/O PROTOCOL CORONARY SINUS ANATOMY What is an Anomaly? DOMINANT LCx STANDARD CRANIAL- TO-CAUDAL ACQUISITION NON- DOMINANT LCx Normal the anatomy seen in >99% of the population 6 Variant unusual anatomy seen in >1% of the population Anomaly unusual and uncommon anatomy seen in <1% of the population Coronary Artery Anomalies Anomalies of Origin High takeoff Multiple ostia Single coronary artery Anomalous origin of the coronary artery from the pulmonary artery* Origin of coronary artery from the opposite or noncoronary sinus with an anomalous course (either retroaortic, interarterial,* prepulmonic, septal (subpulmonic). Anomalies of Course Myocardial bridging* Duplication of arteries Anomalies of termination Coronary artery fistulas* Coronary arcade Extracardiac termination *-Potentially hemodynamically significant or malignant abnormalities Anomalies of Course Myocardial Bridging Myocardial bridging - When a coronary artery runs intramurally within the myocardium instead of epicardially. Encased segment called tunneled artery. Superficial bridge (75%) (no deviation into myocardium) Deep Bridge (25%) (Dips, ie U-shaped, into myocardium) 12
13 SUPERFICIAL AND DEEP MYOCARDIAL BRIDGE Sung-Min Ko Int J Cardiovasc Im,, 2007 DEEP MYOCARDIAL BRIDGE Deep Superficial Anomalies of Course Myocardial Bridging Additional Facts Myocardial Bridging Usually asymptomatic with good prognosis. Has been associated with arrhythmia, unstable angina, myocardial infarction and sudden death. Incidence ranges from % in angiographic studies to 15-85% in pathologic series and thus, may be considered an anatomic variant rather than a true anomaly. 5.7% incidence on CTA (Sung-Min Ko,, et.al. Int J Cardiovasc Im Oct. 2007) When symptoms occur they often don t manifest until the third decade of life. MB predisposes artery to atherosclerosis proximal to bridge. Large multicenter studies needed for incidence and link between MB and chest pain. Anomalies of Origin ANOMALOUS RCA- INTERARTERIAL COURSE A coronary artery that arises from the opposite or noncoronary cusp can take any one of four common courses: 1. interarterial (between aorta and pulmonary artery) 2. retroaortic 3. prepulmonic 4. septal (subpulmonic( subpulmonic) The course taken by the anomalous artery is critically important as the retroaortic, prepulmonic and septal courses are considered benign while the interarterial course can be associated with sudden cardiac death. 13
14 Left Main Arising from Right Coronary Cusp with Interarterial Course Left Main Arising from Right Coronary Cusp with Interarterial Course Rt. Ant. PA Rt. Lt. Ao Ao Non Lt. PA Axial MIP and Volume rendered images show the Left main Coronary artery originating from the right coronary cusp and coursing between the aorta and pulmonary artery. The schematic diagram depicts a similar situation. A second case demonstrating an anomalous origin of the left main coronary artery from the right coronary cusp with interarterial course. MIP images in various projections display the anomaly, however, the sagittal MIP image on the right confirms the interarterial course Left Main Arising from Right Coronary Cusp with Interarterial Course Anterior 3D Volume rendered images demonstrate the left main coronary artery arising from the right coronary cusp with interarterial course. The image on the right has had the pulmonary artery digitally removed by changing the window. FROM RIGHT CORONARY CUSP COURSE-BETWEEN RVOT AND AORTIC ROOT Left Main Arising from Right Coronary Cusp with Septal Course LM SINGLE CORONARY ARTERY ANOMALOUS LM ORIGIN- Septal (Subpulmonic)) Course LAD- VENTRAL TO RVOT- Prepulmonic The anomalous left main can be seen descending inferiorly. This septal or subpulmonic course has not been associated with sudden death. LCx- POSTERIOR TO AORTIC ROOT- Retroaortic 14
15 Anomalous Left Coronary Artery Originating From the Pulmonary Artery Anomalous Left Coronary Artery Originating From the Pulmonary Artery Left main coronary artery is seen originating from the posterior pulmonary artery. Note the large size of both the left main, LAD and the right coronary artery. SAME CASE AS PREVIOUS SLIDE: ALCAPA with large right coronary artery. The RCA is hypertrophied as it is providing collateral flow to the left coronary bed. Note the intramyocardial collateral vessels on the MIP image on the right. Anomalous Pulmonary Artery Origin of Either the RCA or LCA Also known as ALCAPA or Bland-White White- Garland syndrome. A rare congenital defect that represents only % 0.5% of all congenital cardiac defects. Usually an isolated defect, but can be associated with other anomalies such as ASD, VSD and aortic coarctation in approximately 5% of cases. Anomalous Pulmonary Artery Origin of Either the RCA or LCA Symptoms usually present at months of age when LCA pressures rise and PA pressures decrease causing left to right shunting. Without treatment, approximately 90% of infants will die in the first year of life. Survival beyond infancy occurs when there are abundant intercoronary collaterals or the LCA supplies relatively less area of the myocardium. Anomalies of Termination Coronary Artery Fistula Usually congenital and accounts for % 0.4% of congenital cardiac anomalies. Most are clinically and hemodynamically insignificant and are found incidentally. Approximately 60% of coronary artery fistulas originate from the right coronary artery. Anomalies of Termination Coronary Artery Fistula Coronary artery can communicate with either a chamber of the heart (coronary-cameral fistula) or a segment of the systemic or pulmonary circulation (coronary arteriovenous fistula). Stealing of blood to the low pressure systemic circulation leaves myocardium at risk for ischemia. In response, the coronary dilates and may progress to frank aneurysm which can ulcerate, thrombose or rupture. 15
16 Anomalies of Termination Coronary Arteriovenous Fistula Anomalies of Termination Coronary Arteriovenous Fistula Ao A complex fistula is seen between the left main coronary artery and the pulmonary artery. Note the tortuous vessels and the contrast spill into the PA (arrows). Another example of a complex coronary artery fistula, this one associated with a coronary artery aneurysm (arrows). The fistula is from the LAD and continues beyond the aneurysm as a serpiginous vessel over the main pulmonary artery. Anomalies of Termination Coronary Arteriovenous Fistula (Coronary Anatomy-Swine Model) SELECTIVE CTA AORTIC ROOT CTA X-RAY X ANGIO EX-VIVO SAME CASE AS PRVIOUS SLIDE: Complex coronary artery fistula from the LAD to the pulmonary artery with aneurysm (arrows). CONCLUSION MULTIDETECTOR CTA THE END THANK YOU kbis@beaumont beaumont.eduedu High Temporal and Spatial Resolution 2D-MPR, 3D and 4D-MIP and VR Techniques Detailed Depiction of Cardiac and Coronary Anatomy 16
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