The Circulatory System
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1 The Circulatory System By Mr. Danilo Villar Rogayan Jr. Instructor I, Department of Natural Sciences College of Agriculture & Veterinary Medicine RMTU San Marcelino
2 Introduction The cardiovascular system consists of heart and blood vessels Sends blood to Lungs for oxygen Digestive system for nutrients CV system also circulates waste products to certain organ systems for removal from the blood 27-2
3 27-3 The Heart: Structures Cone-shaped organ about the size of a loose fist In the mediastinum Extends from the level of the second rib to about the level of the sixth rib Slightly left of the midline
4 The Heart: Structures (cont.) Heart is bordered: Laterally by the lungs Posteriorly by the vertebral column Anteriorly by the sternum Rests on the diaphragm inferiorly 27-4
5 The Heart: Structures (cont.) Heart coverings Pericardium 27-5 Covers the heart and large blood vessels attached to the heart Visceral pericardium Innermost layer Directly on the heart Parietal pericardium Layer on top of the visceral pericardium Click for Larger View Heart walls: Epicardium Outermost layer Fat to cushion heart Myocardium Middle layer Primarily cardiac muscle Endocardium Innermost layer Thin and smooth Stretches as the heart pumps
6 The Heart: Structures (cont.) Four chambers Two atria Upper chambers Left and right Separated by interatrial septum Two ventricles Lower chambers Left and right Separated by interventricular septum Atrioventricular septum separates the atria from the ventricles Click for View of Heart 27-7
7 The Heart: Structures (cont.) Tricuspid valve prevents blood from flowing back into the right atrium when the right ventricle contracts Bicuspid valve prevents blood from flowing back into the left atrium when the left ventricle contracts Pulmonary valve prevents blood from flowing back into the right ventricle Aortic valve prevents blood from flowing back into the left ventricle Click for View of Heart 27-8
8 The Heart: Blood Flow Deoxygenat ed blood in from body Oxygenated blood in lungs Oxygenated blood out to body Deoxygenate d blood out to lungs Atria Contract Ventricles Contract 27-10
9 The Heart: Blood Flow (cont.) Right Atrium Tricuspid Valve Right Ventricle Pulmonary Valve Body Lungs Aortic Semilunar Valve Left Ventricle Bicuspid Valve Left Atrium Pulmonary Semilunar Valve 27-11
10 The Heart: Cardiac Cycle One heartbeat = one cardiac cycle Atria contract and relax Ventricles contract and relax Right atrium contracts Tricuspid valve opens Blood fills right ventricle Right ventricle contracts Tricuspid valve closes Pulmonary semilunar valve opens Blood flows into pulmonary artery Left atrium contracts Bicuspid valve opens Blood fills left ventricle Left ventricle contracts Bicuspid valve closes Aortic semilunar valve opens Blood pushed into aorta 27-12
11 The Heart: Cardiac Cycle (cont.) Influenced by Exercise Parasympathetic nerves Sympathetic nerves Cardiac control center Body temperature Potassium ions Calcium ions 27-13
12 The Heart: Heart Sounds One cardiac cycle two heart sounds (lubb and dubb) when valves in the heart snap shut Lubb First sound When the ventricles contract, the tricuspid and bicuspid valves snap shut Dubb Second sound When the atria contract and the pulmonary and aortic valves snap shut 27-14
13 The Heart: Cardiac Conduction System Group of structures that send electrical impulses through the heart Sinoatrial node (SA node) Wall of right atrium Generates impulse Natural pacemaker Sends impulse to AV node Bundle of His Between ventricles Two branches Sends impulse to Purkinje fibers Atrioventricular node (AV node) Between atria just above ventricles Atria contract Sends impulse to the bundle of His Purkinje fibers Lateral walls of ventricles Ventricles contract Link to Diagra m 27-15
14 Blood Vessels: Arteries and Arterioles Strongest of the blood vessels Carry blood away from the heart Under high pressure Vasoconstriction Vasodilation Arterioles Small branches of arteries Aorta Takes blood from the heart to the body Coronary arteries Supply blood to heart muscle 27-17
15 Blood Vessels: Veins and Venules Blood under no pressure in veins Does not move very easily Skeletal muscle contractions help move blood Sympathetic nervous system also influences pressure Venules Small vessels formed when capillaries merge Superior and inferior vena cava Largest veins Carry blood into right atrium Valves prevent backflow 27-18
16 Blood Vessels: Capillaries Branches of arterioles Smallest type of blood vessel Connect arterioles to venules Only about one cell layer thick Oxygen and nutrients can pass out of a capillary into a body cell Carbon dioxide and other waste products pass out of a body cell into a capillary 27-19
17 Checkpoint!!! How do arteries control blood pressure? ANSWER: The muscular walls of arteries can constrict to increase blood pressure or dilate to decrease blood pressure
18 Blood Pressure Force blood exerts on the inner walls of blood vessels Highest in arteries Lowest in veins Systolic pressure Ventricles contract Blood pressure is at its greatest in the arteries Diastolic pressure Ventricles relax Blood pressure in arteries is at its lowest Reported as the systolic number over the diastolic number 27-21
19 Blood Pressure (cont.) Control is based mainly on the amount of blood pumped out of the heart The amount of blood entering should equal the amount pumped from the heart Starling's law of the heart Blood entering the left ventricle stretches the wall of the ventricle The more the wall is stretched The harder it will contract and tte more blood it will pump out 27-22
20 Blood Pressure (cont.) Baroreceptors Also help regulate blood pressure Located in the aorta and carotid arteries High blood pressure in aorta message to cardiac center in brain decreases heart rate lowers blood pressure Low blood pressure in aorta message to cardiac center in the brain increases heart rate increases blood pressure 27-23
21 Checkpoint!!! What is the difference between the systolic pressure and diastolic pressure? ANSWER: Systolic pressure is the result of the contraction of the ventricles increasing the pressure in the arteries. Diastolic pressure is the result of the relaxation of the ventricles lowering the pressure in the arteries
22 Circulation Pulmonary circuit right atrium right ventricle pulmonary artery trunk pulmonary arteries lungs pulmonary veins heart (left atrium) Systemic circuit left atrium left ventricle aorta arteries arterioles capillaries venules veins vena cava heart (right atrium) 27-25
23 Circulation (cont.) Arterial system Carry oxygen-rich blood away from the heart Pulmonary arteries carry oxygen-poor blood Paired left and right artery of the same name 27-26
24 Circulation (cont.) Venous system Carries oxygen-poor blood toward the heart Except pulmonary veins Most large veins have the same names as the arteries they are next to Hepatic portal system Collection of veins carrying blood to the liver Click for Larger View
25 Checkpoint!!! Do pulmonary arteries carry blood with high levels of oxygen or low levels of oxygen? ARTERIES: Pulmonary arteries carry oxygen-poor blood
26 Blood A type of connective tissue Red blood cells (erythrocytes) White blood cells (leukocytes) Platelets cell fragments Plasma fluid part of blood Average-sized adult has 4 to 6 liters of blood Amount depends on: Size of person Amount of adipose tissue Concentrations of ions Females have less than males 27-30
27 Blood Components Hematocrit The percentage of red blood cells Normal is about 45% White cells and platelets = 1% Plasma = 55% 27-31
28 Blood Components: Red Blood Cells Erythrocytes Transport oxygen throughout the body Small biconcave-shaped cells Hemoglobin is a pigment in RBCs Oxyhemoglobin carries oxygen; bright red Deoxyhemoglobin does not carry oxygen; darker red Carries carbon dioxide, so also called carboxyhemoglobin Anemia low RBC count Erythropoietin regulates production of RBCs 27-32
29 Blood Components: Red Blood Cells (cont.) 27-33
30 Blood Components: White Blood Cells Granulocytes Neutrophils (55%) destroy bacteria, viruses, and toxins in the bloodstream (phagocytes) Eosinophils (3%) get rid of parasitic infections such as worm infections Basophils (1%) control inflammation and allergic reactions Agranulocytes Monocytes (8%) destroy bacteria, viruses, and toxins in blood Lymphocytes (33%) provide immunity for the body 27-34
31 Blood Components: White Blood Cells (cont.) WBC count normally 5000 to 10,000 cells per cubic millimeter of blood Leukocytosis Elevated WBC count Usually due to infection Leukopenia Low WBC count Some viral infections and other conditions 27-35
32 Blood Components: Platelets Fragments of cells found in the bloodstream Also called thrombocytes Important in the clotting process of blood Normal count 130,000 to 360,000 platelets per cubic millimeter of blood 27-36
33 Blood Components: Plasma Liquid portion of blood composed mostly of water Proteins Albumins Smallest plasma proteins Pull water in to help maintain blood pressure Globulins transport lipids and fat-soluble vitamins Fibrinogen needed for blood clotting Nutrients Amino acids Glucose Nucleotides Lipids from the digestive tract Gases oxygen, carbon dioxide, and nitrogen Electrolytes Waste products 27-37
34 Blood: Bleeding Control Hemostasis the control of bleeding Three processes of hemostasis Blood vessel spasm Platelet plug formation Blood coagulation 27-38
35 27-39 Blood Types Types are distinguished by antigen and antibodies Agglutination Clumping of red blood cells Antigens on surface of RBCs bind to antibodies in plasma
36 Blood Types (cont.) Blood Type Antigen Present Antibody Present Blood That Can Be Received A A B A and O B B A B and O AB AB None A, B, AB, and O O None A and B O 27-40
37 Blood Types (cont.) Rh antigen protein on RBCs Rh-positive RBCs contain the Rh antigen Rh-negative RBCs do not contain the Rh antigen Rh-positive blood is given to Rh-negative person Antibodies form If Rh-negative person receives more Rhpositive blood Antibodies bind to the donor cells Agglutination occurs 27-41
38 Chest Pain Cardiac Myocardial infarction Angina Pericarditis Coronary spasm Take all complaints of chest pain seriously! Non-cardiac Heartburn Panic attacks Pleurisy Costochondritis Pulmonary embolism Sore muscles Broken ribs 27-42
39 27-43 Chest Pain (cont.) Determine cause Electrocardiogram Stress tests Blood tests Chest x-ray Nuclear scan Coronary catheterization Echocardiogram Endoscopy
40 27-44 Diseases and Disorders of the Cardiovascular System Disease Anemia Aneurysm Arrhythmias Carditis Endocarditis Description The blood does not have enough red blood cells or hemoglobin to carry an adequate amount of oxygen to the body s cells A ballooned, weakened arterial wall Abnormal heart rhythms Inflammation of the heart Inflammation of the innermost lining of the heart, including valves
41 27-45 Diseases and Disorders of the Cardiovascular System (cont.) Disease Myocarditis Pericarditis Congestive Heart Failure Coronary Artery Disease (CAD) Description Inflammation of the muscular layer of the heart Inflammation of the membranes that surround the heart (pericardium) Weakening of the heart over time; heart is unable to pump enough blood to meet body s needs Atherosclerosis; narrowing of coronary arteries caused by hardening of the fatty plaque deposits within the arteries
42 27-46 Diseases and Disorders of the Cardiovascular System (cont.) Disease Hypertension Leukemia Murmurs Myocardial Infarction Description High blood pressure; consistent resting blood pressure equal to or greater than 140/90 mm Hg Bone marrow produces a large number of abnormal WBCs Abnormal heart sounds Heart attack; damage to cardiac muscle due to a lack of blood supply
43 27-47 Diseases and Disorders of the Cardiovascular System (cont.) Disease Sickle Cell Anemia Thalassemia Thrombophlebitis Varicose Veins Description Abnormal hemoglobin causes RBCs to change to a sickle shape; abnormal cells stick in capillaries Inherited form of anemia; defective hemoglobin chain causes, small, pale, and short-lived RBCs Blood clots and inflammation develops in a vein Twisted, dilated veins
44 Checkpoint!!! The doctor has told your patient she has anemia. How would you explain this to the her? ANSWER: Anemia is a condition in which a person does not have enough red blood cells or hemoglobin in the blood to carry an adequate amount of oxygen to body cells
45 In Summary Cardiovascular system Transport system for body Heart, arteries, veins, and capillaries Blood Transport medium RBCs, WBCs, platelets, plasma Medical assistant Assists patients in understanding prevention and treatments for cardiovascular problems 27-49
46 27-50
47 Lakô hã salamát! Maraming salamat!
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