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1 documentation V xls Page 1 of 5 Bypass anastomosis for heart revascularization (cabg) : HEART REVASC BYPASS ANAS* valveexclusion : HEART ANEURYSM EXCISION : PARTIAL VENTRICULECTOMY Other repair of heart and : THOR VESSEL RESECT/ANAST : RESECT THORAC VES W REPL Aortic Replacement (aorticvalve) : REPLACE AORT VALV-TISSUE : REPLACE AORTIC VALVE NEC Mitral Replacement (mitralvalve) : REPLACE MITR VALV-TISSUE : REPLACE MITRAL VALVE NEC Mitral Repair (mitralrepair) : OPN MITRAL VALVULOPLASTY : ANNULOPLASTY Pulmonary Valve (pulmonaryvalve) : REPLACE PULM VALV-TISSUE : REPLACE PULMON VALVE NEC : OPN PULMON VALVULOPLASTY Tricuspid Valve (tricuspidvalve) : REPLACE TRIC VALV-TISSUE : REPLACE TRICUSP VALV NEC : OPN TRICUS VALVULOPLASTY Other Valve (othervalve) : OPEN VALVULOPLASTY NOS : OPN AORTIC VALVULOPLASTY : REPLACE HEART VALVE NOS : PAPILLARY MUSCLE OPS : CHORDAE TENDINEAE OPS : INFUNDIBULECTOMY : TRABECUL CARNEAE CORD OP : TISS ADJ TO VALV OPS NEC Double Valve AVR + MVR or AVR + MV Repair If any of these procedures occurs on the same date as a valve procedure, the valve procedure is not included in either the isolated valve group or CABG + valve. Isolated AVR requires absence of valveexclusion, absence of CABG, no MVR, and no MV Repair. CABG+AVR requires absence of valveexclusion, CABG on same date as AVR, no MVR, and no MV Repair. Isolated MVR requires absence of valveexclusion, absence of CABG, and no AVR. CABG+MVR requires absence of valveexclusion, CABG on date of MVR and no AVR. Isolated MV Repair requires absence of valveexclusion, absence of CABG, no AVR, and no MVR. CABG+MV Repair requires absence of valveexclusion, CABG on same date as mitral repair, no AVR, and no MVR. Does not include pulmonary or tricuspid valves! NOTE: Presence of any of these PX does not exclude patient from valve study! Isolated CABG study group and CABG + Valve study Definition of valve study Isolated AVR and CABG + AVR Study Group Isolated MVR and CABG + MVR Study Group Isolated MV Repair and CABG + Mitral Repair Study Group Risk Factor in valve models. Extracorporeal circulation auxiliary to open heart surgery (ecc) : EXTRACORPOREAL CIRCULAT Needed to define other surgery group. Ancillary for other cardiac surgeries we keep track off, but do not generate models for Heart Resection (pericardiectomy) : PERICARDIECTOMY : HEART ANEURYSM EXCISION : EXC/DEST OTH HRT LESION occurs on same date and lead to exclusion of patient from isolated keep track off but do not

2 documentation V xls Page 2 of 5 Heart Resection (pericardiectomy) Heart Repair (heartrepair) : CATH ABLATION LES HEART valve and CABG + valve study! All other PX do not : PARTIAL VENTRICULECTOMY lead to exclusion of the patient from the valve study : Excision or destruction of left. 374: REPAIR OF HEART AND PERICARDIUM Heart transplantation (hearttransplant) : HEART TRANSPLANTATION Combined heart-lung transplantation (heartlun 33.6 Aortic Aneurysm (vesselresection) Other cardiac surgery 336: COMB HEART/LUNG TRANSPLA : THOR VESSEL RESECT/ANAST : RESECT THORAC VES W REPL is not considered an exclusion PX for valve study is an exclusion PX for valve study. Should not co-occur with a valve or CABG PX! Should not co-occur with a valve or CABG PX! PX are considered exclusionary for valve. PCI (pci) : PTCA-1 VES/ATH W/O AGENT : PTCA-1 VES/ATH W AGENT : PTCA-MULTIPLE VESSEL/ATH Not used as single study group, only in combination with : INSERTION OF NON-DRUG- ACS DX : OTHER REMOVAL OF : PERCUTANEOUS Acute MI (PDDami) 410.x 410: ACUTE MYOCARDIAL INFARCT* Risk Factor STEMI present at admit (stemi_atadmit) : AMI ANTEROLATERAL WALL* : AMI ANTERIOR WALL NEC* : AMI INFEROLATERAL WALL* : AMI INFEROPOSTERIOR WALL* : AMI INFERIOR WALL NEC* : AMI LATERAL WALL NEC* : TRUE POSTERIOR INFARCT* : MYOCARDIAL INFARCT NEC* NSTEMI present at admit (nstemi_atadmit) : SUBENDOCARDIAL INFARCT* Procedure on single vessel (single_vessel) Any of Pericardiectomy, Heart Repair, Heart Transplant, Combined Heart-Lung Transplant, Aortic Aneurysm, or any other cardiac surgery (35.xx-38.xx) that does not co-occur with a CABG, AVR, MVR, or mitral valve repair and that requires ECC on date of cardiac surgery. 0040: PROCEDURE ON SINGLE VESSEL Needed to define PCI no ACS single vessel study group Procedure on multiple vessels (multi_vessel) : PROCEDURE ON TWO VESSELS Needed to define PCI no 0042: PROCEDURE ON THREE ACS multi vessel study VESSELS group 0043: PROCEDURE ON FOUR OR MORE VESSELS PCI with ACS PCI with STEMI or NSTEMI present at admission Study Group PCI without ACS PCI without STEMI or NSTEMI present at admission Study Group PCI without ACS single vessel PCI without STEMI or NSTEMI present at admission and single vessel PX Study Group PCI without ACS multi vessel PCI without STEMI or NSTEMI present at admission and multi vessel PX Study Group

3 documentation V xls Page 3 of 5 Acute MI Post-Op (PDDamiNEW) 410.x 410: ACUTE MYOCARDIAL INFARCT* Must be NOT present at admission (CPOA code N) Post-Op AMI Acute MI ALL (PDDamiANY) 410.x 410: ACUTE MYOCARDIAL INFARCT* Use in definition of Post-Op AMI if found for an admission after surgery/intervention admission. Post-Op AMI Stroke Present at Admission (PDDstroke) : IATROGEN CV : OCL BSLR ART W INFRCT : OCL CRTD ART W INFRCT Used to capture pre-op strokes. Stroke Post-Op (PDDstrokeNEW) : IATROGEN CV Must be NOT present at admission (CPOA code N) Post-Op Stroke : OCL BSLR ART W INFRCT Used to capture post-op strokes that occurred after : OCL CRTD ART W INFRCT surgery/intervention during the admission of the Stroke All (PDDstrokeANY) : IATROGEN CV Post-Op Stroke : OCL BSLR ART W INFRCT : OCL CRTD ART W INFRCT Dialysis with CABG (PDDdialysisCABG) : HEMODIALYSIS Dialysis with PCI (PDDdialysispci) : HEMODIALYSIS Dialysis with Aortic Valve (PDDdialysisValveAor : HEMODIALYSIS Dialysis with Mitral Valve (PDDdialysisValveMit : HEMODIALYSIS Dialysis with Mitral Valve (PDDdialysisValveMit : HEMODIALYSIS Dialysis with Double Valve (PDDdialysisValveDo : HEMODIALYSIS Used to capture post-op strokes in admission subsequent to the surgery/intervention admission. Must occur prior to date of CABG. Must occur prior to date of PCI Must occur prior to date of aortic valve. Must occur prior to date of MVR. Must occur prior to date of MV Repair. Risk Factor CABG Risk Factor PCI Risk Factor AVR Risk Factor MVR Must occur prior to date of double valve. Cardiogenic Shock (PDDcardshock) : CARDIOGENIC SHOCK Risk Factor PDDacuityCABG Admission type unscheduled admitted through ER, and CABG on date of admission. Risk Factor CABG PDDacuityPCI Admission type unscheduled admitted through ER, and PCI on date of admission. Risk Factor PCI PDDacuityValveAortic Admission type unscheduled admitted through ER, and AVR on date of admission. Risk Factor AVR PDDacuityValveMitral Admission type unscheduled admitted through ER, and MVR on date of admission. Risk Factor MVR

4 documentation V xls Page 4 of 5 PDDacuityValveMitralRepair Admission type unscheduled admitted through ER, and MV Repair on date of admission. PDDacuityValveDouble Admission type unscheduled admitted through ER, and both valves on date of admission. Diabetes (PDDdiabetes) : DIABETES MELLITUS UNCOMP* Risk Factor : DIABETES W KETOACIDOSIS* : DIAB W HYPEROSMOLAR : DIABETES WITH COMA NEC* : DIAB W RENAL MANIFEST* : DIAB W OPHTHALMIC MANIF* : DIAB W NEUROLOGIC MANIF* : DIABETES W CIRCULAT DIS* : DIABETES W COMPLIC NOS* CHF (PDDchf) : RHEUMATIC HEART FAILURE Risk Factor : BENIGN HYP HRT DIS W CHF : HYPERTEN HEART DIS W CHF : MAL HYPER HRT/REN W CHF : MAL HYP HRT/REN W CHF&RF : BEN HYPER HRT/REN W CHF : BEN HYP HRT/REN W CHF&RF : HYPER HRT/REN NOS W CHF : HYP HT/REN NOS W CHF&RF COPD (PDDcopd) 490.x 490: BRONCHITIS NOS Risk Factor 494.x 494: BRONCHIECTASIS* 496.x 496: CHR AIRWAY OBSTRUCT NEC 430.x 430: SUBARACHNOID HEMORRHAGE 431.x 431: INTRACEREBRAL HEMORRHAGE 432.x 432: INTRACRANIAL HEM NEC/NOS* 433.x 433: PRECEREBRAL OCCLUSION* 434.x 434: CEREBRAL ARTERY OCCLUS* 435.x 435: TRANSIENT CEREB ISCHEMIA* 436.x 436: CVA 437.x 437: OTH CEREBROVASC DISEASE* 438.x 438: LATE EFF CEREBROVASC DIS* PVD (PDDpvd) 440.x 440: ATHEROSCLEROSIS* Risk Factor : THORACIC AORTIC ANEURYSM : ABDOM AORTIC ANEURYSM : THRACABD ANURYSM WO RUPT : AORTIC ANEURYSM NOS : THROMBOANGIIT OBLITERANS : PERIPH VASCULAR DIS NEC* : PERIPH VASCULAR DIS NOS : STRICTURE OF ARTERY : CHR VASC INSUFF INTEST : VASC INSUFF INTEST NOS V43.4 V434: BLOOD VESSEL REPLAC NEC Cardiomyopathy (PDDcardiomyopathy) 425.x 425: CARDIOMYOPATHY* Risk Factor Renal Failure (PDDrenalfailure) 585.x 585: CHRONIC RENAL FAILURE Risk Factor 586.x 586: RENAL FAILURE NOS

5 documentation V xls Page 5 of 5 V42.0 V420: KIDNEY TRANSPLANT STATUS V45.1 V451: RENAL DIALYSIS STATUS V56.0 V560: RENAL DIALYSIS ENCOUNTER V56.8 V568: DIALYSIS ENCOUNTER, NEC : BEN HYP RENAL W REN FAIL : HYP RENAL NOS W REN FAIL : BEN HY HT/REN W REN FAIL : HY HT/REN NOS W REN FAIL Atrial fibrillation and flutter (427.3) (PDDAfib) : ATRIAL FIBRILL/FLUTTER* Risk Factor Infectious Endocarditis (421.0) (PDDendocardit : AC/SUBAC BACT ENDOCARD Risk Factor Prior CABG (PDDpriorCABG) V45.81 V4581: AORTOCORONARY BYPASS Risk Factor Prior PCI (PDDpriorPCI_V) V45.82 V4582: STATUS-POST PTCA Risk Factor Prior Valve - Tissue (PDDpriorValve1) V42.2 V422: HEART VALVE TRANSPLANT Risk Factor Prior Valve - Mechanical (PDDpriorValve2) V43.3 V433: HEART VALVE REPLAC NEC Risk Factor Aortic/Mitral Valve Disease/Stenosis/Insufficiency 396.x 396: MITRAL/AORTIC VALVE DIS* Risk Factor CABG with Heart Catherization (PDDcathCABG) : RT HEART CARDIAC CATH : LEFT HEART CARDIAC CATH Cath must be placed on day of CABG. Risk Factor CABG Aortic Valve with Heart Catherization : RT HEART CARDIAC CATH (PDDcathValveAortic) : LEFT HEART CARDIAC CATH Cath must be placed on day of Aortic Valve. Risk Factor AVR Mitral Valve with Heart Catherization : RT HEART CARDIAC CATH (PDDcathValveMitral) : LEFT HEART CARDIAC CATH Cath must be placed on day of MVR. Risk Factor MVR Mitral Repair with Heart Catherization : RT HEART CARDIAC CATH (PDDcathValveMitralRepair) : LEFT HEART CARDIAC CATH Cath must be placed on day of Mitral Valve Repair. Double Valve with Heart Catherization : RT HEART CARDIAC CATH (PDDcathValveDouble) : LEFT HEART CARDIAC CATH Cath must be placed on day of Double Valve.

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