1 Adult Congenital Heart Disease: A Growing Problem Dr. Gary Webb Cincinnati Children s Hospital Heart Institute
3 ACHD Resources in Ohio ACHAHEART.ORG
4 Situations When We Might Help When you don t know a lot about a CHD diagnosis. When a CHD diagnosis includes a person s name. Fontan. Mustard. Senning. Rastelli. Jatene.
5 Situations When We Might Help CHD patients who are cyanotic. CHD patients with pulmonary hypertension. CHD patients with only one ventricle. CHD patients needing noncardiac surgery. CHD patients needing special cardiac surgery. David operation. Ross procedure. Aortic valve repair.
6 Situations When We Might Help CHD patient candidates for a heart catheterization. Sexually active CHD patients. CHD patients contemplating pregnancy. Pregnant CHD patients. CHD patients with arrhythmias. CHD patients with syndromes.
7 Consider ACHD clinics to contain resource people who have developed networks of specialists with special interests and abilities.
8 The Toronto Congenital Cardiac Centre for Adults founded 1959
10 Patient 63 - History 31-year-old female supermarket clerk 16 weeks pregnant. Cyanotic at birth. Left BT shunt at age 11. Lateral tunnel Fontan procedure at age 20. Lost to follow-up until age 31.
12 Patient 63 - History NYHA class I. No functional decline recently. No medications.
13 Patient 63 Risk Factors Don t know much about that. Fontan. Blalock Taussig. Man s name. Pregnancy.
14 What is a Fontan procedure? I don t know. A type of transposition repair. A type of tetralogy repair. A type of single ventricle repair.
15 What are the pregnancy issues associated with a Fontan procedure? Choose as many as are applicable Atrial flutter. Thromboembolism. Fetal loss. Cyanosis. Maternal death. All of the above.
16 Patient 63
17 Patient 63
18 Fontan Pregnancy Management Close monitoring. High-risk pregnancy team. Consider anticoagulation. Planned vaginal delivery. Planned epidural.
19 Patient 63 Patient Course and Outcome Induced at 39 weeks. Epidural anesthetic. Normal vaginal delivery. Healthy baby boy.
21 Patient 61 - History 24-year-old man, works as an engineer. Born with tricuspid atresia. Palliated with bilateral Blalock-Taussig shunts. Atriopulmonary Fontan procedure at age 6. Started on warfarin at age 16 for possible pulmonary embolism.
23 Patient 61 - History At age 17, developed recurrent atrial flutter. Treated with various antiarrhythmics, including amiodarone. By age 21, was in chronic atrial fibrillation. Was otherwise doing well (NYHA I).
25 Patient 61 - Physical Examination Bilateral thoracotomy and midline sternotomy scars. JVP hard to assess. Chest clear. Normal precordial examination. Normal heart sounds with no murmurs. No hepatomegaly, ascites, or edema.
26 Patient 61 Risk Factors Don t know much about that. Fontan. Blalock Taussig. Man s name. Arrhythmia. One ventricle.
27 Patient 61
28 Patient 61 - What next steps? Optimize anticoagulation. Refer for immediate surgery. Consider thrombolysis. No specific treatment needed.
29 Patient 61 Decision and Management A Fontan revision was elected. Right atrial thrombus removed along with excess right atrial tissue. Extracardiac Fontan constructed. Arrhythmia surgery not possible because of operative difficulties.
31 Patient 61 Decision and Management Immediately postoperatively Hemodynamically unstable Persistent bleeding Sternal closure impossible, so skin only closure. Maximum pressors.
32 Patient 61 Decision and Management Postoperative complications Compartment syndrome left leg. Recurrent tension pneumothorax. Acute tubular necrosis Tracheotomy.. Discharged home after four months, in atrial fibrillation, and on warfarin.
33 Patient 61
35 Patient 53 - History 38-year-old woman Original CHD diagnoses TGA VSD PS Age 7, Rastelli procedure with a 20 mm Dacron conduit including a Hancock valve
36 Rastelli Procedure
37 Patient 53 - History Age 25, Strep sanguis endocarditis She was found to have severe conduit obstruction, moderate subaortic stenosis, a small residual VSD, and preserved biventricular function. Her conduit was replaced using a homograft, her VSD was enlarged to reduce the LVOT gradient, and a baffle was placed between LV and the aorta.
38 Patient 53 - History Age 35, heart catheterization showed a 40 mmhg gradient across the RV-PA conduit with mild LVOTO and mild AR. Sotalol was started for suspected paroxysmal atrial tachycardia. Age 38, NYHA class III with exertional dyspnea and fatigue. She is limited to 100 yards on the flat. She avoids steps. Current medications: warfarin; sotalol 80 mg BID; furosemide 20 mg daily; sertraline 100 mg daily
40 Patient 53 - Physical Examination JVP 8 cm ASA. Chest clear. Possible right ventricular lift. Second sound loud and single. Grade 4 long ejection systolic murmur upper left sternal border. No hepatomegaly or edema.
41 How much conduit obstruction does she have? Mild. Moderate. Severe. Don t know.
42 Patient 53
43 Patient 53
44 Patient 53 - Echo Report Normal LV size and function. Peak LVOT gradient 20 mmhg. RVH with mild-moderate hypokinesis. Mild TR. Valved conduit not seen.
45 Patient 53 Risk Factors Don t know much about that. TGA. VSD/PS. Man s name. Exercise intolerance. Sexually active.
46 Patient 53
47 Patient 53
48 Patient 53
49 Patient 53
50 Patient 53 Why is she NYHA class III? Choose as many as are applicable The stenosed conduit? The sotalol? Chronotropic incompetence? Anemia? Lung disease?
51 Patient 53 Management and Outcome Conduit from RV to PA removed and replaced. Smooth postop course. Patient NYHA I after convalescence.
53 Patient 41 - History 31-year-old woman Original CHD diagnoses Tetralogy of Fallot Age 3, transannular patch repair. Progressive pulmonary regurgitation, severe. Asymptomatic and full time work, but has slowed down a bit.
58 Patient 41 - Echo Report Normal LV size and function. Right ventricle severely dilated. Laminar (severe) pulmonary regurgitation.
59 Patient 41 Risk Factors Don t know much about that. Tetralogy. Pulmonary regurgitation. Man s name. Candidate for a heart catheterization.
60 Patient 41
61 Patient 41
62 Patient 41
63 Patient 41 Pulmonary Regurgitant Fraction 48%
64 Patient 41 Treatment Options? Choose as many as are applicable Bioprosthetic pulmonary valve replacement. Mechanical pulmonary valve replacement. Percutaneous pulmonary valve replacement. Continued observation.
65 Patient 41 Plan and Outcome Pulmonary valve replacement elected. 23 mm homograft used (bioprosthesis). Previous patch excised. Exercise intolerance for improved after convalescence. RV volumes reduced by 30% on follow-up MRI.
67 Patient 25 - History 45-year-old man Original CHD diagnoses Aortic coarctation (isolated) Age 3, coarctation repair (details unknown). Recently found to have high blood pressure. Treated with an ACE inhibitor and a beta blocker. No cardiovascular symptoms.
68 Patient 25 - Physical Examination BP 156/70 right arm 115/60 left arm 118/? right thigh Pulse 44 Height 70 inches Weight 202 pounds Pulse oximetry 98%
69 Patient 25 - Physical Examination Left thoracotomy scar. Pulse delay right radial to right femoral. Very weak pedal pulses. Grade 2 ejection systolic murmur. Grade 2-3 murmur of aortic regurgitation. Faint continuous murmur heard over the back.
70 Patient 25
71 Patient 25
72 Patient 25 Patient 25 - Echo Report Bicuspid aortic valve. Mild aortic regurgitation. Normal left ventricular size and function. Coarctation gradient 47 mmhg with diastolic tail
73 Patient 25 - MRI Report Mild dilation of the ascending aorta. Hypoplastic distal aortic arch with severe coarctation. Collateralization present.
74 Patient 25 - MRI
75 Patient 25 Risk Factors Possible candidate for cardiovascular surgery. Possible candidate for a heart catheterization.
76 Patient 25 Treatment Options? Choose as many as are applicable Surgical repair of aortic coarctation. Balloon dilation of aortic coarctation. Stent placement for aortic coarctation. More aggressive antihypertensive therapy.
77 Patient 25 Plan and Outcome Stent therapy of aortic recoarctation elected.
78 Patient 25 Plan and Outcome BP right arm BP left arm BP right leg Prior to procedure 156/70 115/60 118/? 3 weeks after procedure 108/65 113/70 132/80
79 Patient 25 Plan and Outcome
80 Case 19
81 Patient 19 - History 26-year-old woman Original CHD diagnoses Normal heart Infective endocarditis Age 9 and 10, aortic valve repair for aortic regurgitation. Age 18, Ross procedure. Age 26, declining exercise capacity, limited to two floors vertically.
87 Patient 19 - Echo Report Left ventricle dilated to 62 mm diastolic. Normal LV systolic function. Ascending aortic dilation to 55 mm. Severe neoaortic valve regurgitation. Homograft function normal on the right side of the heart.
88 Patient 19 - Echo
89 Patient 19 - Echo
90 Patient 19 Risk Factors CHD patients needing special cardiac surgery. David operation. Ross procedure. Aortic valve repair?
91 Patient 19 - Which management would you consider? Choose as many as are applicable Bentall procedure with mechanical aortic valve. Bentall procedure with bioprosthetic aortic valve. Valve sparing root replacement.
92 Patient 19 Management and Outcome Valve sparing aortic root replacement elected. At surgery, the neoaortic valve leaflets appeared normal. The aortic annulus was less dilated than were the sinuses. The aorta was replaced using a David technique, sewing a 26 mm Dacron graft with preformed sinuses down to the annulus with resuspension of the neoaortic leaflets. The coronary arteries were reimplanted.
93 Patient 19 Management and Outcome The patient did well with no residual aortic valve regurgitation.
94 Patient 19 Management and Outcome
95 Case 6
96 Patient 6 - History 34-year-old woman Generally healthy childhood. Told that her heart was on the right side. Occasional episodes of hemoptysis as a teenager. Hemoptysis recurred after a recent successful pregnancy. Lifelong non-smoker. Very good exercise capacity.
98 Patient 6 - Physical Examination Normal JVP. Clear chest. Right-sided apical impulse. Heart sounds normal, no murmurs. Right-sided liver.
99 Patient 6
100 Patient 6
101 Patient 6 - Echo Report Dextroposition of the heart with normal cardiac chamber anatomy. Mild right heart dilation. Normal RVSP.
102 Patient 6 - MRI
103 Patient 6 - MRI
104 Patient 6 Patient 6 - MRI
105 Patient 6 - CT
106 Patient 6 Patient 6 - CT
107 Patient 6 Risk Factors Don t know much about that. Anomalous pulmonary venous connection. Scimitar syndrome.
108 Patient 6 - What management would you consider? Choose as many as are applicable Observation. Surgical repair of scimitar circulation. Embolization of anomalous arterial supply. Surgical resection of abnormal lung segment.
109 Patient 6 Management and Outcome Observation was elected. Many patients with scimitar syndrome have a shunt less than 2/1 and do not need redirection of their venous return. She did not have lung sequestration on CT scanning. Her lung parenchyma was normal. Over an 8-year follow-up, the patient has done well.
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