Heart Failure in Congenital Heart Disease
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1 Heart Failure in Congenital Heart Disease
2 Robert E. Shaddy (Editor) Heart Failure in Congenital Heart Disease From Fetus to Adult
3 Editor Robert E. Shaddy The Children s Hospital of Philadelphia School of Medicine Philadelphia, PA ISBN e-isbn DOI / Springer London Dordrecht Heidelberg New York British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Control Number: Springer-Verlag London Limited 2011 Apart from any fair dealing for the purposes of research or private study, or criticism or review, as permitted under the Copyright, Designs and Patents Act 1988, this publication may only be reproduced, stored or transmitted, in any form or by any means, with the prior permission in writing of the publishers, or in the case of reprographic reproduction in accordance with the terms of licences issued by the Copyright Licensing Agency. Enquiries concerning reproduction outside those terms should be sent to the publishers. The use of registered names, trademarks, etc., in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore free for general use. Product liability: The publisher can give no guarantee for information about drug dosage and application thereof contained in this book. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature. Cover design: estudiocalamar, Figueres/Berlin Printed on acid-free paper Springer is part of Springer Science+Business Media (
4 Preface Survival outcomes for patients with congenital heart disease have greatly improved over the last two decades. Because of better and longer survival in these patients who often have abnormal ventricular morphology, the incidence of heart failure in this patient population has also increased. Although there is a significant evidence base for the treatment of heart failure in adults, the evidence base for treating children and adults with congenital heart disease is significantly less. The purpose of this book is to describe the current state-of-theart for the diagnosis and treatment of heart failure in patients with congenital heart disease. v
5 Contents 1 Heart Failure in the Fetus with Congenital Heart Disease... Deepika Thacker and Jack Rychik 2 Unique Aspects of Heart Failure in the Neonate Jack F. Price 3 Chronic Heart Failure in Children with Congenital Heart Disease Kimberly Y. Lin and Robert E. Shaddy 4 Heart Failure in Adults with Congenital Heart Disease Konstantinos Dimopoulos, Georgios Giannakoulas, and Michael A. Gatzoulis 1 5 Indications and Outcomes of Heart Transplantation in the Patient with Congenital Heart Disease Charles E. Canter 6 Right Ventricular Failure in Congenital Heart Disease Luis Antonio Altamira and Andrew N. Redington 7 Mechanical Circulatory Support in the Patient with Congenital Heart Disease Chitra Ravishankar, Troy E. Dominguez, Tami M. Rosenthal, and J. William Gaynor 8 Electrophysiology Issues and Heart Failure in Congenital Heart Disease Scott R. Ceresnak and Anne M. Dubin Index vii
6 Contributors Luis Antonio Altamira, MD The Hospital for Sick Children, University of Toronto Toronto, Ontario, Canada Michael A. Gatzoulis, MD, PhD Professor of Cardiology, National Heart and Lung Institute, Imperial College, London, UK Charles E. Canter, MD St. Louis Children s Hospital, Washington University St. Louis, MO, USA J. William Gaynor, MD Department of Surgery, Scott R. Ceresnak, MD Lucile Packard Children s Hospital, Stanford University Palo Alto, CA, USA Konstantinos Dimopoulos, MD, MSc, PhD Royal Brompton Hospital, Sydney Street, London, UK Georgios Giannakoulas, MD, PhD Royal Brompton Hospital, Sydney Street, London, UK Troy E. Dominguez, MD Great Ormond Street Hospital for Children, London, UK Kimberly Y. Lin, MD Anne Dubin, MD Lucile Packard Children s Hospital, Stanford University Palo Alto, CA, USA Jack F. Price, MD Texas Children s Hospital, Baylor College of Medicine, Houston, TX, USA ix
7 x Chitra Ravishankar, MD Pediatrics, The Children s Hospital of Philadelphia, Andrew N. Redington, MB, BS, MRCP (UK), MD, FRCP (UK), FRCP (C) The Hospital for Sick Children, University of Toronto Toronto, Ontario, Canada Tami M. Rosenthal, MD Division of Cardiothoracic Surgery, Contributors Jack Rychik, MD Robert E. Shaddy, MD Deepika Thacker, MBBS
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