Expanding Horizons: AngioVac Suction Thrombectomy at UTHealth
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1 Expanding Horizons: AngioVac Suction Thrombectomy at UTHealth Naveed Saqib, MD Assistant Professor Department of Cardiothoracic and Vascular Surgery McGovern Medical School The University of Texas Science Center at Houston Memorial Hermann Heart & Vascular Institute
2 AngioVac Large bore 22 Fr cannula with Funnel tip Suction to engage and remove Emboli trap Simultaneous reinfusion of filtered blood
3 AngioVac Simple veno-veno extracorporeal circuit No reservoir Centrifugal pump In-line filter Real time reinfusion
4 Device Approval Jun 2009 Aug 2009 Dec 2013 Mar 2014 Cannula Circuit CE Mark FDA Expanded indications The AngioVac cannula is intended for use as a venous drainage cannula and for the removal of fresh, soft thrombi or emboli during extracorporeal bypass for up to six hours
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6 Introduction Experience of using novel Vacuum assisted aspiration thrombectomy device AngioVac (Angiodynamics) is increasing No single case series reporting the experience of Vacuum assisted aspiration thrombectomy catheter in both venous and arterial thrombus extraction
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8 Study Design 08/ /2017 Memorial Hermann Hospital 9 patients Inclusion Criteria Outcomes
9 Study Design Inclusion Criteria Age 16 years All patients undergoing Angiovac Thrombectomy Outcomes
10 Study Design Inclusion Criteria Outcomes Mortality 0/9 Complete thrombectomy 8/9 OR time 188 minutes Complications: Hypothermia 1/9 Groin hematoma 1/9
11 AngioVac Thrombectomy Site of thrombosis Superior Vena Cava Descending Aorta and Subclavian Artery Right Atrial Mass Iliocaval DVT
12 AngioVac Thrombectomy Use of Adjunct Measures Rotational thrombectomy device (argon cleaner wire) 6/9 (66%) Balloon angioplasty and stenting 3/9 (33%)
13 40 year old female: Case I 8/8/2015 Right lower extremity phelgmasia LE swelling symptom onset 4 weeks CT scans in Free standing ER`s revealed filling defect in right common iliac vein Anticoagulation not administered
14 Aspiration thrombectomy of Iliocaval DVT 8/9/2015 General anesthesia Hybrid room Open insertion of 26 Fr Dryseal sheath: Right IJ Percutaneous insertion of 17 Fr Biomedicus cannula in Left CFV Extracorporeal Veno-venous Right FV Sheath Operation halted due to hypothermia with residual thrombus
15 Aspiration thrombectomy of Iliocaval DVT 8/16/2015 Use of adjunct mechanical thrombectomy along with Angiovac Successful complete thrombus removal 2 year followup with patent IVC and iliac stents On antiplatelet therapy now
16 67 year old female: Case II 9/8/ weeks post CABG at Tyler, Texas Admitted to MHH neurosurgical ICU with: Right ventricular embolism: Pulmonary embolism Left ventricular embolism: Left MCA embolic stroke Left SCA thromboembolism Left LIMA thrombus Floating thrombus in descending throacic aorta
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19 Aspiration Thrombectomy Thoracic Aortic & L SCA Thrombus General anesthesia Hybrid room Open insertion of 26 Fr Dryseal sheath: Right CFA Percutaneous insertion of 17 Fr Biomedicus cannula in Left CFV Extracorporeal Arterio-venous IVC filter placement to prevent recurrence
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23 CASE 2 Aspiration Thrombectomy Thoracic Aortic & L SCA Thrombus
24 Aspiration Thrombectomy Thoracic Aortic & L SCA Thrombus OR time: Followup: 5 hours 2 yrs ASD closure IVC filter retrieved after 12 months
25 Case III 74 year old male with previous Optease IVC filter placed 10 years ago presents with: Dyspnea and chest pain Bilateral lower extremity swelling
26 Case III Venous duplex: Extensive bilateral lower extremity DVT CT PE protocol: Type B PE Systemic anticoagulation started
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28 Aspiration Thrombectomy of Iliocaval DVT 1/14/2016 General anesthesia Hybrid room Open insertion of 26 Fr Dryseal sheath: Right IJ Percutaneous insertion of 16 Fr Biomedicus cannula in Left IJ Extracorporeal Veno-venous Right FV & Left FV Sheaths Adjunct mechanical thrombectomy by using Argon Cleaner wires
29 Aspiration Thrombectomy of Iliocaval DVT 1/14/2016
30 Aspiration Thrombectomy of Iliocaval DVT 1/14/2016 OR time: Follow-up: On Xarelto 2 hrs 30 mins 18 months
31 CASE IV 63 year old male with prostate cancer Taxotere & Adriamycin via port a cath Port a cath was placed on 10/2015 Right atrial mass identified on Staging CT chest (2/11/2016) Associated small pulmonary emboli
32 CASE IV Patient started on anticoagulation Chemotherapy halted
33 3/1/2016
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35 Aspiration Thrombectomy of Right Atrial Mass 3/2/2016 General anesthesia Hybrid room Intraop TEE Open insertion of 26 Fr Dryseal sheath: Right IJ Right CFV Percutaneous insertion of 17 Fr Biomedicus cannula in Left CFV Extracorporeal Veno-venous
36 Aspiration Thrombectomy of Right Atrial Mass 3/2/2016 Position AngioVac in Right Atrium Flush Filter and Repeat Deploy Funnel / Tulip Advance AngioVac Cannula Initiate and Opimize Flow
37 Aspiration Thrombectomy of Right Atrial Mass 3/2/2016 Position AngioVac in Right Atrium Flush Filter and Repeat Deploy Funnel / Tulip Advance AngioVac Cannula Initiate and Opimize Flow
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41 Aspiration thrombectomy of Right Atrial Mass OR time: Heparin dose: Protamine: 5 hours 12,000 Units 100 mg Intraoperative frozen section: No cardiac tissue Pathology permanent section: Organized thrombus
42 3/7/ year follow-up with CT Scan & TTE revealed no recurrence of thrombus or pulmonary lesion No evidence of prostate cancer metastasis
43 Case V : 33 year old female Large uterine fibroids and metomenorrhagia Previous iliac vein thrombolysis and left iliac vein stent (May Thurner syndrome) Recurrent severe edema LLE
44 CT Abdomen and Pelvis
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46 UFE 6/21/2017
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48 Venogram & Angiojet Thrombolysis MH Sugarland 6/26/2017
49 Aspiration thrombectomy of Iliocaval DVT 6/30/2017 General anesthesia Hybrid room Open insertion of 26 Fr Dryseal sheath: Right IJ Percutaneous insertion of 17 Fr Biomedicus cannula in Left IJ Extracorporeal Veno-venous Bypass Right FV & Left FV Sheaths, Left LSV Sheath Adjunct mechanical thrombectomy by using Argon Cleaner wires & angiojet Iliac vein stenting IVC filter removal
50 Aspiration thrombectomy of Iliocaval DVT 6/30/2017 General anesthesia Hybrid room Open insertion of 26 Fr Dryseal sheath: Right IJ Percutaneous insertion of 17 Fr Biomedicus cannula in Left IJ Extracorporeal Veno-venous Bypass Right FV & Left FV Sheaths, Left LSV Sheath Adjunct mechanical thrombectomy by using Argon Cleaner wires & angiojet Iliac vein stenting IVC filter removal
51 Aspiration thrombectomy of Iliocaval DVT 6/30/2017
52 Conclusion Angiovac suction thrombectomy is a promising alternative to open thrombectomy Angiovac should be added to the armamentarium of vascular surgeons
53 Thank You
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