Reoperation for Left Ventricular Outflow Tract Obstruction After Repair of Atrioventricular Septal Defect
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1 Reoperation for Left Ventricular Outflow Tract Obstruction After Repair of Atrioventricular Septal Defect David M. Overman Division of Pediatric Cardiac Surgery The Children s Heart Clinic Chief, Division of Cardiovascular Surgery Children s Hospitals and Clinics of Minnesota No disclosures
2 Reoperation for Left Ventricular Outflow Tract Obstruction After Repair of Atrioventricular Septal Defect David M. Overman Division of Pediatric Cardiac Surgery The Children s Heart Clinic Chief, Division of Cardiovascular Surgery Children s Hospitals and Clinics of Minnesota
3 Welcome to Spring in Minneapolis!
4 Objectives Morphology of LVOT in AVSD Anatomy of LVOTO in repaired AVSD Surgical strategies for LVOTO Technical details to optimize outcomes
5 Objectives Morphology of LVOT in AVSD Anatomy of LVOTO in repaired AVSD Surgical strategies for LVOTO Technical details to optimize outcomes
6 Objectives Morphology of LVOT in AVSD Anatomy of LVOTO in repaired AVSD Surgical strategies for LVOTO Technical details to optimize outcomes
7 Objectives Morphology of LVOT in AVSD Anatomy of LVOTO in repaired AVSD Surgical strategies for LVOTO Technical details to optimize outcomes
8 Outcomes: Repair of AVSD N = 93 Median f/u: 37.3m Early mortality: 0% Late mortality: 2.2% Pacemaker: 7.5% MR reop: 19.4%
9 Outcomes: Repair of AVSD N = 93 Median f/u: 37.3m Early mortality: 0% Late mortality: 2.2% Pacemaker: 7.5% MR reop: 19.4% Reoperation for LVOTO: 2.2%
10 Outcomes for Repair of Subaortic Stenosis Mortality 2% Recurrent LVOTO 15-20% Permanent pacer 2-15%
11 Late Survival and LVOTO
12 Morphology of LVOT in AVSD Unwedged aorta Inlet/outlet septal length disparity Muscular septal deficiency ( septal scoop ) Anterolateral muscle bundle of LV Anomalies of subvalvar AV apparatus
13 Morphology of LVOT in AVSD Unwedged aorta Inlet/outlet septal length disparity Muscular septal deficiency ( septal scoop ) Anterolateral muscle bundle of LV Anomalies of subvalvar AV apparatus
14 Morphology of LVOT in AVSD Unwedged aorta Inlet/outlet septal length disparity Muscular septal deficiency ( septal scoop ) Anterolateral muscle bundle of LV Anomalies of subvalvar AV apparatus
15 Morphology of LVOT in AVSD; Abnormal Septal Geometry Penkoske PA, et al. JTCVS 90: Gallo, P, et al. Clin Cardiol. 14:
16 Morphology of LVOT in AVSD: Ventricular Septal Scoop Ann Thor Surg 2009;87: % of CAVSD specimens had anterosuperior extension of septal scoop Those with such extension had significantly narrower LVOT Depth of scoop did not affect LVOT diameter
17 Morphology of LVOT in AVSD Unwedged aorta Inlet/outlet septal length disparity Muscular septal deficiency ( septal scoop ) Anterolateral muscle bundle of LV Anomalies of subvalvar AV apparatus
18 Morphology of LVOT in AVSD: Anterolateral Muscle Bundle of LV Draulans Noe, HAY, Wenink, ACG. Pediatr Cardiol. 1991;12: 83-8.
19 Morphology of LVOT in AVSD: Anterolateral Muscle Bundle of LV Horizontal bar between ALMV and LCC in LVOT Present in 40% of normal hearts Draulans Noe, HAY, Wenink, ACG. Pediatr Cardiol. 1991;12: 83-8.
20 Morphology of LVOT in AVSD: Anterolateral Muscle Bundle of LV Present in all AVSD specimens (n=77) Mild to moderate hypertrophy in 43% Unequivocal LVOTO in 6% Draulans Noe, HAY, Wenink, ACG. Pediatr Cardiol. 1991;12: 83-8.
21 Morphology of LVOT in AVSD Unwedged aorta Inlet/outlet septal length disparity Muscular septal deficiency ( septal scoop ) Anterolateral muscle bundle of LV Anomalies of subvalvar AV apparatus
22 Morphology of LVOT in AVSD: Subvalvar AV Apparatus
23 Morphology of LVOT in AVSD: Subvalvar AV Apparatus
24 Outcomes for LVOTO Surgery After AVSD Repair SUBAORTIC STENOSIS IN THE SPECTRUM OF ATRIOVENTRICULAR SEPTAL DEFECTS Solutions may be complex and palliative Glen S. Van Arsdell, Md a (by invitation), William G. Williams, MD a, Christine Boutin, MD b (by invitation), George A. Trusler, MD a,john G. Coles, MD a, Ivan M. Rebeyka, Md a (by invitation), Robert M. Freedom, MD b, c (by invitation) Toronto, Ontario, Canada 19 patients 18/19 fibrous resection,7/19 LAVV procedure Freedom from reoperation 66% at 6 years
25 Outcomes for LVOTO Surgery After AVSD Repair SUBAORTIC STENOSIS IN THE SPECTRUM OF ATRIOVENTRICULAR SEPTAL DEFECTS Solutions may be complex and palliative Glen S. Van Arsdell, Md a (by invitation), William G. Williams, MD a, Christine Boutin, MD b (by invitation), George A. Trusler, MD a,john G. Coles, MD a, Ivan M. Rebeyka, Md a (by invitation), Robert M. Freedom, MD b, c (by invitation) Toronto, Ontario, Canada Standard fibromyectomy for subaortic stenosis in children with atrioventricular septal defect leads to a high rate of reoperation.
26 Outcomes for LVOTO Surgery After AVSD Repair SUBAORTIC STENOSIS IN THE SPECTRUM OF ATRIOVENTRICULAR SEPTAL DEFECTS Solutions may be complex and palliative Glen S. Van Arsdell, Md a (by invitation), William G. Williams, MD a, Christine Boutin, MD b (by invitation), George A. Trusler, MD a,john G. Coles, MD a, Ivan M. Rebeyka, Md a (by invitation), Robert M. Freedom, MD b, c (by invitation) Toronto, Ontario, Canada Because of the potential for multiple causes of obstruction, a tailored operation may be necessary.
27 Outcomes for LVOTO Surgery After AVSD Repair Ann Thor Surg 2012;94: patients 41fibrous resection, 22 LAVV procedure, 27 myectomy, 5 modified Konno, 9 Ao valve repair Freedom from reoperation 81% at 5 years
28 Outcomes for LVOTO Surgery After AVSD Repair Ann Thor Surg 2012;94: LVOTO in AVC is a complex, multifactorial disease that is difficult to address. Aggressive surgical repair has improved late outcomes; however, risk factors for reoperation, and the ideal approach for repair remain to be defined.
29 Surgical Options for LVOTO After AVSD Repair Transaortic resection Modified Konno Leaflet resuspension
30 .Surgical Options for LVOTO Modified Konno Metton O et al. 2008;2008:mmcts MMCTS
31 .Surgical Options for LVOTO Modified Konno Recurrent, complex, multilevel LVOTO Distal LVOT visualization key Risks: ventriculotomy, residual VSD, aortic valve injury
32 .Surgical Options for LVOTO Leaflet Resuspension Starr, A, Hovaguimian, H. JTCVS 1994; 108:373-6.
33 .Surgical Options for LVOTO Leaflet Resuspension Partial or Transitional AVSD Limited data Impact limited by chordal length
34 Pre- Repair TEE
35 MOVIE
36 Post Repair TEE
37 Conclusions Incidence of LVOTO after AVSD repair ~ 2% Anatomic basis of LVOTO after AVSD repair is multifactorial Role of surgical technique is creating LVOTO unclear
38 Conclusions Surgery must address fibromuscular, valvar, and septal/tunnel elements of LVOTO Transaortic resection is usually effective Modified Konno and leaflet resuspension are useful adjuncts
39 Thank You!
40 Reoperation for Left Ventricular Outflow Tract Obstruction After Repair of Atrioventricular Septal Defect David M. Overman Division of Pediatric Cardiac Surgery The Children s Heart Clinic Chief, Division of Cardiovascular Surgery Children s Hospitals and Clinics of Minnesota
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