Routine MitraClip. Image Guidance Step by Step

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1 Routine MitraClip Image Guidance Step by Step Douglas C. Shook, MD, FASE Director, Cardiothoracic Anesthesia Fellowship Director, Cardiac Interventional Anesthesia Department of Anesthesiology BRIGHAM AND WOMEN S HOSPITAL Heart & Vascular Center HARVARD MEDICAL SCHOOL TEACHING HOSPITAL

2 Disclosures Sorin - Speaker Edwards Lifesciences - Speaker

3 Objectives By the end of the presentation, the viewer will be better able to... understand the mitral anatomy as it applies to MitraClip placement. describe the key imaging steps for MitraClip placement. apply an anatomic approach to transesophageal echocardigraphic imaging for MitraClip placement.

4 The MitraClip Procedure

5 The MitraClip Procedure

6 The MitraClip Procedure

7 Ideal Valve Morphology MR originating at A2/P2 (degenerative or functional) Lack of Ca++ in grasping area MVA > 4cm 2 PMVL > 10mm length Flail width <15mm Flail gap <10mm Sufficient tissue for grasping Coaptation depth <11mm Coaptation length >2mm

8 Assessment

9 Assessment

10 Assessment

11 Assessment

12 Assessment

13 Parallax in 3D Imaging

14 Parallax in 3D Imaging

15 Assessment

16 Planning the MitraClip Approach?

17 Planning the MitraClip Approach? Where is the optimal transseptal puncture?

18 Planning the MitraClip Approach? Where is the optimal transseptal puncture? Where do you place this clip?

19 Planning the MitraClip Approach? Where is the optimal transseptal puncture? Where do you place this clip? How do you orient the clip relative to coaptation?

20 Planning the MitraClip Approach? Where is the optimal transseptal puncture? Where do you place this clip? How do you orient the clip relative to coaptation? How do you place the clip there while avoiding the subvalvular apparatus?

21 Planning the MitraClip Approach? Where is the optimal transseptal puncture? Where do you place this clip? How do you orient the clip relative to coaptation? How do you place the clip there while avoiding the subvalvular apparatus? What papillary muscle do the ruptured chords come from?

22 Planning the MitraClip Approach? Where is the optimal transseptal puncture? Where do you place this clip? How do you orient the clip relative to coaptation? How do you place the clip there while avoiding the subvalvular apparatus? What papillary muscle do the ruptured chords come from? How do you grasp the leaflets once you re there?

23 Planning the MitraClip Approach? Where is the optimal transseptal puncture? Where do you place this clip? How do you orient the clip relative to coaptation? How do you place the clip there while avoiding the subvalvular apparatus? What papillary muscle do the ruptured chords come from? How do you grasp the leaflets once you re there? How many clips will be needed to adequately reduce the MR

24 Procedural Steps for MitraClip Transseptal puncture Introduction of the steerable guide catheter into the left atrium Advancement of the clip delivery system into the left atrium Positioning the clip above the mitral valve Advancing the clip into the left ventricle Grasping the leaflets and assessing for insertion MR and MS evaluation Clip detachment and assess need for additional clips Assess for pericardial effusion and other complications

25 Septal Puncture - MitraClip Inf Sup Post Ant Superior Posterior Location

26 Transseptal Puncture Superior and Posterior Location 4-5 cm above the MV annulus

27 Transseptal Puncture Text

28 Dist 3.30 cm Text

29 Transseptal Puncture Text

30 Dist 4.34 cm Text

31 Crossing the Septum

32 Crossing the Septum

33 ME Commissural View P1 P3 A2 Post Pap Ant Pap 0 (40-80 ) Ant PM Post PM

34 ME Commissural View 0 (40-80 ) Ant PM Post PM

35 ME Long Axis View 0 ( ) LA AV LVOT Inf Lat Wall Ant Sept Wall No PM

36 ME Long Axis View 0 ( ) No PM

37 AV P1 A1 A3 P3 A2 P2 P2 Ant Pap LVOT Post Pap

38 MitraClip Positioning AV

39 Positioning the Clip

40 Positioning the Clip AV

41 Positioning the Clip

42 Positioning the Clip AV

43 Positioning the Clip

44 Positioning the Clip AV

45 Positioning the Clip

46 Positioning the Clip AV

47 Positioning the Clip

48 Positioning the Clip AV

49 Positioning the Clip

50 Positioning the Clip AV

51 Turn Down the Gain

52 Turn Down the Gain AV

53 Clip Below the Valve in the LV

54 Clip Below the Valve in the LV

55 Grasping the Leaflets

56 Grasping the Leaflets

57 Releasing the Clip Measured Orifice > 1.5 cm 2

58 Releasing the Clip

59 Releasing the Clip

60 Gradients Lateral Orifice Medial Orifice Mean Gradient < 5 mmhg

61

62 Pulmonary Veins Before After

63 Procedural Steps for MitraClip Transseptal puncture Introduction of the steerable guide catheter into the left atrium Advancement of the clip delivery system into the left atrium Positioning the clip above the mitral valve Advancing the clip into the left ventricle Grasping the leaflets and assessing for insertion MR and MS evaluation Clip detachment and assess need for additional clips Assess for pericardial effusion and other complications

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