Percutaneous Aortic Valve Implantation. Core-Valve and Cribier-Edwards Update
|
|
|
- Eustace Bryce Bradley
- 5 years ago
- Views:
Transcription
1 Percutaneous Aortic Valve Implantation. Core-Valve and Cribier-Edwards Update T. Lefèvre
2 Natural History of Aortic Stenosois 100 Latent period Survival (%) Symptoms Average Age Death Age (years) From Ross and Brauwald, Circulation 1968
3 Euroheart Survey 5001 Patients, April July % NYHA class > 3 had no surgery. Bernard Iung et al. EHJ. 2005; 26:
4 Many Patients Considered too High Risk
5 Many Patients Considered too High Risk
6 Balloon Aortic Dilatation Popularized in the 80s Good acute results Low risk of complication Poor mid-term results Still used in some centers «Bridge» to surgery Palliative treatment Before non cardiac urgent surgery
7 Cribier-Edwards Valve Tricuspid Equine Pericardial valve Balloon expandable Stainless steel bioprothesis (23mm) Durability in vitro > 10 years
8 I-REVIVE / RECAST Feasibility study Veina cava RFV Patients included (n) 36 Procedure performed (n) 33 Implantation success (%) 82 Death1 month(%) 25 Death 6 months (%) 53 Emergency surgery (%) 0 LFA Valve dysfunction (%) 0 Cribier et al. JACC 2006; 47:
9 I-REVIVE / RECAST Hemodynamic results Cribier et al. JACC 2006; 47:
10 Retrograde approach, Vancouver registry Retro FLEX Catheter
11 Retrograde approach, Vancouver registry 30 day mortality % Log. Euroscore John Webb et al. ACC 2006
12 Retrograde approach, Vancouver registry 30 day mortality % Log. Euroscore Mortality John Webb et al. ACC 2006
13 Retrograde approach, Vancouver registry 30 day mortality % Log. Euroscore Mortality Patient 1-23 John Webb et al. ACC 2006
14 Retrograde approach, Vancouver registry 30 day mortality % Log. Euroscore Mortality Patient 1-23 Patient John Webb et al. ACC 2006
15 Edwards THV Clinical Trial Sites Worldwide New York London Rotterdam Aarhus Leipzig Vienna Laval Frankfurt (2) Essen Toronto Vancouver Seattle Los Angeles Chicago Detroit Boston Miami Bern Milan Dallas Cleveland Clinic Aalst Paris Massy Washington DC Atlanta Rouen Madrid (2)
16 Two bioprosthesis sizes: 23 and 26-mm Bovine pericardium
17 Edwards THV Worldwide (Transfemoral) Edwards Aortic Femoral THV (n > 350) Canadian Special Access (Vancouver) n=99 PARTNER Europe PARTNER US REVIVE II Europe & Canada Jan 2006 n=90 REVIVAL II US Dec 2005 n=55
18 REVIVE II: EU Feasibility Trial Multicentre European Study May October 2007 N=30 Roll-in patients N=90 Trial patients
19 REVIVE II: Inclusion Criteria Symptomatic AS, AVA < 0.7 cm 2 Age >70 yrs old Logistic EuroSCORE > 20% or surgical contra-indication
20 REVIVE II: Patient Characteristics Patients (n) Age (years) Female gender (%) EuroSCORE (%) Ejection Fraction (%) AVA baseline (cm 2 ) Mean gradient (mmhg) ± ± ± ± ± 20.6
21 REVIVE II: Access site Complications Jan 06 May 06: 5 complications/20 patients = 25% Vascular screening + User training Aug 06 Aug 07: 5 complications/67 patients = 7.5%
22 REVIVE II: Procedural Complications Coronary occlusion 1.1% Stroke 1.1% Pacemaker 3.4%
23 REVIVE II: All Cause Mortality 1 Freedom from Death % at 1 month (predictive Euroscore: 28.7%) Months Post-Implant
24 Implantation Success Rate % E Revive/Recast Vancouver Revival II Revive II Partner
25 Edwards THV Worldwide (All Transapical) Edwards Aortic THV n > 270 Canadian Special Access (Vancouver) n=44 PARTNER Europe PARTNER US TRAVERCE Europe n=125 REVIVAL II US n=22
26 TRAVERCE Trial (N=125 Pts) Age (years) Female Gender (%) Logistic Euroscore (%) Ejection fraction (%) AVA pre-intervention (%) 26 mm valve (%)
27 TRAVERCE: Procedure Outcomes Patients (n) BAV to Valve deployment (min.) Total procedure Time (min.) Off pump (%) Correct positioning (%) Conversion (%) ± ±
28 TRAVERCE: Mortality Procedure Related - Sudden death - Multi-organ failure - Cardiac failure -Stroke 125 Patients Late Deaths (>30 days) N=18 (14.4%) Early Deaths (<30 days) N=15 (12%) Procedure Related -Sudden death -Multi-organ failure -Cardiac failure -Stroke 14 Non procedural - GI comp. -Stroke -Sepsis -MI 11 Non Procedural - Cardiac failure - Arrhythmia -Bleeding - Multi-organ failure - Leg ischemia - GI comp. - Embolic event
29
30 Next Generation Transcatheter Valve Refined balloon expandable valve frame and delivery system (overall size reduced by 3-5Fr) Refined leaflet geometry The RetroFlex II delivery catheter
31 CoreValve ReValving TM System 18 Fr Delivery System Self-expanding nitinol frame, porcine pericardial valve, and 18 Fr sheathed delivery system
32 CoreValve Self-Expanding Bioprosthesis Clinical Experience: 337 Patients Generation 1 25F Generation 2 21F 14 patients 65 patients Generation 3 18F (258 Pts) Oct 2007
33 CoreValve : Patients Demographics 21F (n=63) 18F (n=112) Age (years) 81 ± 6 82 ± 7 Female gender (%) Logistic EuroSCORE (%) 26 ± ± 14 CAD (%) Prior MI (%) Prior PCI (%) Prior CABG (%) 23 28
34 CoreValve : Patients Demographics 21F (n=63) 18F (n=112) Procedural Success (%) Procedure Time (min) 204±62 151±77
35 CoreValve : Complications 0-30 days 21F (n=63) 18F (n=112) Conversion to surgery (%) 3 4 AMI (%) 2 1 Aortic dissection (%) 3 2 Coronary impairment (%) 2 1 Vascular complications (%) 10 1 Stroke/TIA (%) 5 7 Pacemaker (%) Non Hierarchical events
36 CoreValve : 30-day Mortality 21F (n=63) 18F (n=112) Logistic EuroSCORE (%) Day Mortality 14 15
37 Percutaneous Aortic Valve Implantation In 2008 Surgery Percutaneous > 1000 Pts Pts / year > 40 years experience > 600 Pts > 400 Pts
38 Conclusion Feasibility and efficacy of percutaneous aortic valve implantation in patients at very high risk or with contra-indications to surgery is now clearly demonstrated. Hemodynamic performance and mid-term durability of the valve are excellent.
39 Conclusion The main limitation of the retrograde approach is optimal screening for femoral approach and learning phase of the Team in managing difficulties and complications. When the femoral access is contraindicated, the trans-apical approach seems to be a good alternative.
40 Conclusion Finally, this technique opens a new field in which more patients with symptomatic aortic stenosis will have access to treatment (percutaneous or conventional).
41 The first Human Heart Transplant
42 Percutaneous Aortic Valve Implantation
43 Future Aortic Valve Concepts
44 Next Generation Devices
> 1200 Patients
> 1200 Patients 2002-2008 2008 Transfemoral (n=628) Transapical (n=457) Antegrade N=59 Retrograde N=569 TRAVERCE n=172 RECAST n = 24 REVIVE II n = 106 REVIVAL II n =40 Early First in Man irevive n = 22
Edwards Transcatheter AVR: Have the Outcomes Changed after CE Approval?
Edwards Transcatheter AVR: Have the Outcomes Changed after CE Approval? Update from PARTNER EU and SOURCE Registries T. Lefèvre Disclosure Statement Cardiologist Interventional cardiologist 1 st PABV in
Transcatheter Aortic Valve Implantation Present Status and Perspectives
Transcatheter Aortic Valve Implantation Present Status and Perspectives Angioplasty Summit TCTAP 2010 Alain Cribier, MD University of Rouen, France Transcatheter Aortic Valve Implantation has entered the
TRANSAPICAL AORTIC VALVE REPAIR
TRANSAPICAL AORTIC VALVE REPAIR Mauro ROMANO M.D. Department of Cardio-Vascular Surgery Institut Cardiovasculaire Paris Sud Institut Hospitalier Jacques Cartier MASSY FRANCE romano.mauro@orange.fr Treatment
2/28/2010. Speakers s name: Paul Chiam. I have the following potential conflicts of interest to report: NONE. Antegrade transvenous transseptal route
Transcatheter Aortic Valve Implantation Asian perspective Speakers s name: Paul Chiam Paul TL Chiam MBBS, MRCP, FACC I have the following potential conflicts of interest to report: NONE Consultant National
Transcatheter Aortic Valve Implantation. SSVQ November 23, 2012 Centre Mont-Royal 15:40
Transcatheter Aortic Valve Implantation SSVQ November 23, 2012 Centre Mont-Royal 15:40 Nicolo Piazza MD, PhD, FRCPC, FESC, FACC McGill University Health Center German Heart Center Munich 1 First-in-Human
Incorporating the intermediate risk in Transcatheter Aortic Valve Implantation (TAVI)
Incorporating the intermediate risk in Transcatheter Aortic Valve Implantation (TAVI) Larry S. Dean, MD, MSCAI Past President SCAI Professor of Medicine and Surgery University of Washington School of Medicine
Results of Transapical Valves. A.P. Kappetein Dept Cardio-thoracic surgery
Results of Transapical Valves A.P. Kappetein Dept Cardio-thoracic surgery Rotterda am, The Netherlands 2002 FIM 2003 2005 2006 2010 THV THV Cribier-Edwards Edwards Edwards Sapien Sapien XT Bovine pericardium
Percutaneous Treatment of Valvular Heart Diseases: Lessons and Perspectives. Bernard Iung Bichat Hospital, Paris
Percutaneous Treatment of Valvular Heart Diseases: Lessons and Perspectives Bernard Iung Bichat Hospital, Paris Euro Heart Survey on Valvular Diseases 3547 Patients with Native Valve Disease n= 1250 1000
TAVI: The Real Deal? Marc Pelletier, MD Head, Department of Cardiac Surgery New Brunswick Heart Centre
TAVI: The Real Deal? Marc Pelletier, MD Head, Department of Cardiac Surgery New Brunswick Heart Centre Disclosure St. Jude Medical: Consultant and Proctor Edwards Lifesciences: Proctor Medtronic: Research
1-YEAR OUTCOMES FROM JOHN WEBB, MD
1-YEAR OUTCOMES FROM JOHN WEBB, MD ON BEHALF OF THE SAPIEN 3 INVESTIGATORS UNIVERSITY OF BRITISH COLUMBIA VANCOUVER, CANADA Potential conflicts of interest Speaker's name: John Webb I have the following
Late failure of transcatheter heart valves: An open question
Late failure of transcatheter heart valves: An open question A comparison with surgically implanted bioprosthetic heart valves. A. Rashid The Cardiothoracic Centre Liverpool, UK. Conflict of Interest Statement
3 years after introduction of TAVI in QEH. Michael KY Lee On Behalf of QEH TAVI Heart Team Queen Elizabeth Hospital Hong Kong
3 years after introduction of TAVI in QEH Michael KY Lee On Behalf of QEH TAVI Heart Team Queen Elizabeth Hospital Hong Kong HA Convention 2014 Introduction Aortic Stenosis most common valvular heart disease
Transcatheter Aortic Valve Replacement: Current and Future Devices: How do They Work, Eligibility, Review of Data
Transcatheter Aortic Valve Replacement: Current and Future Devices: How do They Work, Eligibility, Review of Data Echo Florida 2013 Jonathan J. Passeri, M.D. Co-Director, Heart Valve Program Director,
Australia and New Zealand Source Registry Edwards Sapien Aortic Valve 30 day Outcomes
Australia and New Zealand Source Registry Edwards Sapien Aortic Valve 30 day Outcomes A/ Professor Darren Walters On behalf of the ANZ Source Investigators Director of Cardiology Brisbane, Australia ANZ
Le TAVI pour tout le monde?
Le TAVI pour tout le monde? Thierry Lefèvre Institut Cardiovasculaire Paris Sud, Massy Disclosure Statement of Financial Interest I currently have, or have had over the last two years, an affiliation or
A new option for the Diagnosis and Management of Valvular Heart Disease. Oregon Comprehensive Valve Center
A new option for the Diagnosis and Management of Valvular Heart Disease Oregon Comprehensive Valve Center I have no disclosures Oregon Comprehensive Valve Center Weekly multidisciplinary case conferences
An Update on the Edwards TAVR Results. Zvonimir Krajcer, MD Director, Peripheral Intervention Texas Heart Institute at St.
An Update on the Edwards TAVR Results Zvonimir Krajcer, MD Director, Peripheral Intervention Texas Heart Institute at St. Luke s Hospital Disclosures On the speaker s bureau for Endologix, TriVascular,
TAVI: Transapical Procedures
Cardiology Update Davos TAVI: Transapical Procedures Volkmar Falk, MD University Hospital Zürich TA-AVI: antegrade, simple, safe The front door approach! Transapical TAVI Technical advantages of TA approach
Igor Palacios, MD Director of Interventional Cardiology Massachusetts General Hospital Professor of Medicine Harvard Medical School
Aortic Stenosis: Current State of Percutaneous Therapies, Emerging Technologies and Future Directions Igor Palacios, MD Director of Interventional Cardiology Massachusetts General Hospital Professor of
Results of Transfemoral Transcatheter Aortic Valve Implantation
Results of Transfemoral Transcatheter Aortic Valve Implantation Saudi Heart Association, February 21-24 Rüdiger Lange, MD, PhD Nicolo Piazza, MD, FRCPC, FESC German Heart Center, Munich, Germany Division
Bernard De Bruyne, MD, PhD Cardiovascular Center Aalst OLV-Clinic Aalst, Belgium
Medium Term Survival and Functional Status in Patients with Severe Aortic Stenosis Treated by Transcatheter Aortic Valvular Implantation in the PARTNER EU Trial Bernard De Bruyne, MD, PhD Cardiovascular
Valve Replacement without a Scalpel Transcatheter Aortic Valve Replacement (TAVR) Charles T. Klodell, M.D.
Valve Replacement without a Scalpel Transcatheter Aortic Valve Replacement (TAVR) Charles T. Klodell, M.D. Professor, Thoracic and Cardiovascular Surgery University of Florida klodell@surgery.ufl.edu Disclosures
Aortic Stenosis Background and Breakthroughs in Treatment: TAVR Update
Aortic Stenosis Background and Breakthroughs in Treatment: TAVR Update Howard J Broder MD Interventional Cardiology DaVita Medical Group/ Healthcare Partners Cardiology Disclosures for Howard J Broder
Percutaneous Valve Interventions. Percutaneous Valve Interventions
Percutaneous Valve Interventions Stanton J. Rowe President, Percutaneous Valve Interventions Edwards is Best Positioned to Capitalize on Percutaneous Valve Opportunities #1 global valve replacement and
30-day Outcomes of The CENTERA Trial a New Self-Expanding Transcatheter Heart Valve. Didier Tchétché, MD On Behalf of the CENTERA Investigators
30-day Outcomes of The CENTERA Trial a New Self-Expanding Transcatheter Heart Valve Didier Tchétché, MD On Behalf of the CENTERA Investigators Speaker's name: Didier Tchétché, MD I have the following potential
Eberhard Grube, MD, FACC, FSCAI
TCT Asia Seoul, April 29, 2010 MDT / Core Valve Device Evolution, Technique and Clinical Trial Update Eberhard Grube, MD, FACC, FSCAI Intl. Heart Center Rhein-Ruhr, Essen, Germany Hospital Oswaldo Cruz
Masterclass III Advances in cardiac intervention. Percutaneous valvular intervention a novel approach
Masterclass III Advances in cardiac intervention Percutaneous valvular intervention a novel approach Professor Roger Boyle CBE National Director for Heart Disease and Stroke London Medical therapy Medical
Multicentre clinical study evaluating a novel resheatable self-expanding transcatheter aortic valve system
Multicentre clinical study evaluating a novel resheatable self-expanding transcatheter aortic valve system Preliminary Results: Acute and 1-year Outcomes Ganesh Manoharan, MBBCh, MD, FRCP Consultant Cardiologist
TAVR today: High Risk, Intermediate Risk Population, and Valve in Valve Therapy
TAVR today: High Risk, Intermediate Risk Population, and Valve in Valve Therapy Alan Zajarias, MD FACC Structural Interventional Fellowship Director Associate Professor Medicine Cardiovascular Division
TAVI: Present and Future Perspective
TAVI: Present and Future Perspective Igor F. Palacios, M.D. Director of Interventional Cardiology Massachusetts General Hospital Professor of Medicine Harvard Medical School Percutaneous transcatheter
Percutaneous Aortic Valvuloplasty: Long-Term Survival
Percutaneous Aortic Valvuloplasty: Long-Term Survival Angioplasty Summit Seoul April 27, 2007 James R. Margolis MD Carmen Paez MD, Kevin Coy MD, Edward Freeman PhD Miami International Cardiology Consultants
Transcatheter Aortic Valve Replacement
Transcatheter Aortic Valve Replacement Jesse Jorgensen, MD Medical Director, Cardiac Catheterization Laboratory Greenville Health System Greenville, South Carolina, USA January 30, 2016 Aortic Stenosis
TAVR SPRING 2017 The evolution of TAVR
TAVR SPRING 2017 The evolution of TAVR Matthew Johnson, MD Disclosers None Evolution of the Balloon- Expandable Transcatheter Valves Cribier 2002 SAPIEN 2006 SAPIEN XT 2009 SAPIEN 3 2013 * Sheath compatibility
Predicting the Future for Transcatheter Valve Therapies: New Devices and Expanded Clinical Indications Martin B. Leon, MD Columbia University Medical
Predicting the Future for Transcatheter Valve Therapies: New Devices and Expanded Clinical Indications Martin B. Leon, MD Columbia University Medical Center Cardiovascular Research Foundation New York
The Transcatheter Aortic Valve Replacement (TAVR)Program at Southcoast Health. Adam J. Saltzman, MD Cardiovascular Care Center
The Transcatheter Aortic Valve Replacement (TAVR)Program at Southcoast Health Adam J. Saltzman, MD Cardiovascular Care Center Southcoast Health Disclosures Edwards Lifesciences: speaking honorarium Outline
Strokes After TAVR. Incidence (past and present) Multi-factorial Origin
Strokes After TAVR Incidence (past and present) Multi-factorial Origin Samir Kapadia, MD Professor of Medicine Director, Cardiac Catheterization Laboratory Cleveland Clinic All faculty disclosures are
Aortic Stenosis: Background
Transcatheter Aortic Valve Replacement in Low Surgical Risk Patients Barry George, MD The Ohio State University Structural Heart Disease Course May 19 th, 2017 Aortic Stenosis: Background Severe Symptomatic
Aortic stenosis (AS) remains the most common
Sapien Valve: Past, Present, and Future A look at how the Sapien family of valves continues to evolve to treat a range of patients seeking transcatheter aortic valve replacement. BY RAVINDER SINGH RAO,
Istanbul Course of Interventional Cardiology Istanbul, June 11, 2011
Istanbul Course of Interventional Cardiology Istanbul, June 11, 2011 Within the past 12 months, the presenter or their spouse/partner have had a financial interest/arrangement or affiliation with the organization(s)
Stainless Steel. Cobalt-chromium
Sapien is better than Corevalve! Raj R. Makkar, MD Associate Director, Cedars-Sinai Heart Institute Associate Professor, UCLA School of Medicine, Los Angeles Eberhard Grube: Pioneer in the field of TAVR
TAVI- Is Stroke Risk the Achilles Heel of Percutaneous Aortic Valve Repair?
TAVI- Is Stroke Risk the Achilles Heel of Percutaneous Aortic Valve Repair? Elaine E. Tseng, MD and Marlene Grenon, MD Department of Surgery Divisions of Adult Cardiothoracic and Vascular and Endovascular
Aortic valve implantation using the femoral and apical access: a single center experience.
Aortic valve implantation using the femoral and apical access: a single center experience. R. Hoffmann, K. Brehmer, R. Koos, R. Autschbach, N. Marx, G. Dohmen Rainer Hoffmann, University Aachen, Germany
Is TAVR Now Indicated in Even Low Risk Aortic Valve Disease Patients
Is TAVR Now Indicated in Even Low Risk Aortic Valve Disease Patients Saibal Kar, MD, FACC, FAHA, FSCAI Director of Interventional Cardiac Research Cedars Sinai Heart Institute, Los Angeles, CA Potential
The Development of Interventional Cardiology for the Treatment of Degenerative Aortic Valve Stenosis: a 20 Years Odyssey
The Development of Interventional Cardiology for the Treatment of Degenerative Aortic Valve Stenosis: a 20 Years Odyssey Andreas Gruntzig lecture, ESC 2010, Stockholm, 29 Aug 2010 Alain Cribier, MD University
Clinical and Echocardiographic Outcomes at 30 Days with the SAPIEN 3 TAVR System in Inoperable, High-Risk and Intermediate-Risk AS Patients
Clinical and Echocardiographic Outcomes at 30 Days with the SAPIEN 3 TAVR System in Inoperable, High-Risk and Intermediate-Risk AS Patients Susheel Kodali, MD on behalf of The PARTNER Trial Investigators
TAVR-Update Andrzej Boguszewski MD, FACC, FSCAI Vice Chairman, Cardiology Mid-Michigan Health Associate Professor Michigan State University, Central
TAVR-Update Andrzej Boguszewski MD, FACC, FSCAI Vice Chairman, Cardiology Mid-Michigan Health Associate Professor Michigan State University, Central Michigan University 1 Disclosure Chiesi Pharma- Consultant
30-Day Outcomes Following Implantation of a Repositionable Self-Expanding Aortic Bioprosthesis: First Report From the FORWARD Study
30-Day Outcomes Following Implantation of a Repositionable Self-Expanding Aortic Bioprosthesis: First Report From the Study Stephan Windecker Department of Cardiology Bern University Hospital - INSELSPITAL
Transcatheter aortic valve implantation for severe aortic valve stenosis with the ACURATE neo2 valve system: 30-day safety and performance outcomes
All cited trademarks are the property of their respective owners. CAUTION: The law restricts these devices to sale by or on the order of a physician. Indications, contraindications, warnings and instructions
Valvular Intervention
Valvular Intervention Outline Introduction Aortic Stenosis Mitral Regurgitation Conclusion Calcific Aortic Stenosis Deformed Eccentric Calcified Nodular Rigid HOSTILE TARGET difficult to displace prone
Aortic Stenosis: Interventional Choice for a 70-year old- SAVR, TAVR or BAV? Interventional Choice for a 90-year old- SAVR, TAVR or BAV?
Aortic Stenosis: Interventional Choice for a 70-year old- SAVR, TAVR or BAV? Interventional Choice for a 90-year old- SAVR, TAVR or BAV? Samin K Sharma, MD, FACC, FSCAI Director Clinical & Interventional
Appropriate Use of TAVR - now and in the future. A Surgeon s Perspective. Neil Moat Royal Brompton Hospital, London, UK
Appropriate Use of TAVR - now and in the future A Surgeon s Perspective Neil Moat Royal Brompton Hospital, London, UK Disclosure Statement of Financial Interest Within the past 12 months, I or my spouse/partner
Update on Percutaneous Therapies for Structural Heart Disease. William Thomas MD Director of Structural Heart Program Tucson Medical Center
Update on Percutaneous Therapies for Structural Heart Disease William Thomas MD Director of Structural Heart Program Tucson Medical Center NCVH 2014- Tucson Disclosure of Financial Interest Research: Stock
Portico (St. Jude Medical Inc, St.
Review Article Portico Transcatheter Heart Valve Apostolos Tzikas 1,2, Michael Chrissoheris 2, Antonios Halapas 2, Konstantinos Spargias 2 1 Interbalkan European Medical Centre, Thessaloniki, 2 Hygeia
Establishing the New Standard of Care for Inoperable Aortic Stenosis THE PARTNER TRIAL COHORT B RESULTS
Establishing the New Standard of Care for Inoperable Aortic Stenosis THE PARTNER TRIAL COHORT B RESULTS E D W A R D S T R A N S C A T H E T E R H E A R T V A L V E P R O G R A M T H E P A R T N E R T R
TAVI: Nouveaux Horizons
TAVI: Nouveaux Horizons EUAPI580i 432HQ14NP02353 Institut de Cardiologie de la Pitié-Salpêtrière jean-philippe.collet@psl.aphp.fr www.action-coeur.org Objectifs Les recommandations Le TAVI en chiffre La
TAVR in patients with. End-Stage CKD or in Renal Replacement Therapy:
TAVR in patients with End-Stage CKD or in Renal Replacement Therapy: Special Considerations and Prevention of early Valve Failure Antonios Chalapas, MD, PhD, FESC THV & Hygeia Hospital Heart Team Athens,
CIPG Transcatheter Aortic Valve Replacement- When Is Less, More?
CIPG 2013 Transcatheter Aortic Valve Replacement- When Is Less, More? James D. Rossen, M.D. Professor of Medicine and Neurosurgery Director, Cardiac Catheterization Laboratory and Interventional Cardiology
Transcatheter Aortic Valve Replacement with Evolut-R
Transcatheter Aortic Valve Replacement with Evolut-R Department of Transcatheter Heart Valves and 2 nd Cardiothoracic Surgery Clinic K. Spargias, M.Chrissoheris, A.Halapas, I. Nikolaou, S.Pattakos Disclosures
Progress In Transcatheter Aortic Valve Implantation
Progress In Transcatheter Aortic Valve Implantation Gerald Yong MBBS (Hons) FRACP FSCAI Interventional Cardiologist Royal Perth Hospital Western Australia 4 th APCASH 8 th Sept 2013 Disclosure Statement
Prince Sultan Cardiac Center Experience Riyadh, Saudi Arabia
Transcatheter Transapical Aortic Valve Implantation Prince Sultan Cardiac Center Experience Riyadh, Saudi Arabia Ahmed Elwatidy, MD,PhD, FRCS S Kassab, MD,S Ahmari, MD, H Amri, MD, H Ismail, MD, A Calafiori,
TAVR for low-risk patients in 2017: not so fast.
TAVR for low-risk patients in 2017: not so fast. Enrico Ferrari, MD, FETCS Cardiac Surgery Department Cardiocentro Ticino Foundation Lugano, Switzerland Conflicts of Interest Consultant and proctor for
Incidence and Management of Early Implant Failure after Transcatheter Aortic Valve Implantation
ESC Congress 2010 28 Aug 2010-01 Sep 2010 Stockholm - Sweden Incidence and Management of Early Implant Failure after Transcatheter Aortic Valve Implantation Gian Paolo Ussia, MD Director of Interventional
Early Experience of Transcatheter Mitral Valve Replacement Results from the Intrepid Global Pilot Study
Early Experience of Transcatheter Mitral Valve Replacement Results from the Paul Sorajja, MD for the Investigators Presenter Disclosure Information Within the past 12 months, I or my spouse/partner have
VALVULOPATIE: NUOVE SOLUZIONI.
VALVULOPATIE: NUOVE SOLUZIONI www.fisiokinesiterapia.biz Nkomo, Lancet 2006 ELDERLY POPULATION PROJECTION IN USA 65-84 Years Old 85 and Older 77,2 Millions of people 34,8 4,3 30,5 53,8 6,8 47 14,3 62,9
Transcatheter Aortic Valve Implantation Management of risks and complications
Transcatheter Aortic Valve Implantation Management of risks and complications TAVI Summit, Seoul, Korea, Spetember 3rd, 2011 Alain Cribier University of Rouen, France Complications of TAVI Depending on
Strokes After TAVR Multi-factorial Origin, Incidence (past and present), and Management Considerations (present and future)
Strokes After TAVR Multi-factorial Origin, Incidence (past and present), and Management Considerations (present and future) Samir Kapadia, MD Professor of Medicine Director, Cardiac Catheterization Laboratory
Alternate Vascular Access for TAVR. Gian Paolo Ussia Campus Bio-medico University, Rome Italy
Alternate Vascular Access for TAVR Gian Paolo Ussia Campus Bio-medico University, Rome Italy g.ussia@unicampus.it REQUIRED Gian Paolo Ussia I have no relevant financial relationships Transcatheter Valves
THE PERCUTANEOUS MANAGEMENT OF VALVULAR HEART DISEASE DR JOHN RAWLINS CONSULTANT INTERVENTIONAL CARDIOLOGIST UNIVERSITY HOSPITAL SOUTHAMPTON
THE PERCUTANEOUS MANAGEMENT OF VALVULAR HEART DISEASE DR JOHN RAWLINS CONSULTANT INTERVENTIONAL CARDIOLOGIST UNIVERSITY HOSPITAL SOUTHAMPTON INTRODUCTION History of heart valve intervention Current indications
Establishing a New Path Forward for Patients With Severe Symptomatic Aortic Stenosis THE PARTNER TRIAL CLINICAL RESULTS
Establishing a New Path Forward for Patients With Severe Symptomatic Aortic Stenosis THE PARTNER TRIAL CLINICAL RESULTS E D W A R D S T R A N S C A T H E T E R H E A R T V A L V E P R O G R A M T h e Pa
Vascular complications of embolized core valve
Vascular complications of embolized core valve Suhail Dohad, MD FACC Director of Endovascular services, Interventional Cardiology Cardiovascular Research Foundation of Southern California, CVMG Director
Paris, August 28 th Gian Paolo Ussia on behalf of the CoreValve Italian Registry Investigators
Paris, August 28 th 2011 Is TAVI the definitive treatment in high risk patients? Impact Of Coronary Artery Disease In Elderly Patients Undergoing TAVI: Insight The Italian CoreValve Registry Gian Paolo
2 Brigham and Women s Hospital, Boston, MA.
Chapter 6: History of Transcatheter Aortic Valve Replacement (TAVR) Bryan Piccirillo, MD 1 ; Pinak B. Shah, MD, FACC 2 1 Brigham and Women s Heart and Vascular Center 2 Brigham and Women s Hospital, Boston,
Dr.ssa Loredana Iannetta. Centro Cardiologico Monzino
Dr.ssa Loredana Iannetta Centro Cardiologico Monzino Bicuspid aortic valve BAV is the most common congenital cardiac anomaly. Estimated incidence is 2% in general population. 4:1 male predominance. Frequency
VALVULAR HEART DISEASE AORTIC VALVE STENOSIS TAVR PROCEDURE
CVI SYMPOSIUM 2012 VALVULAR HEART DISEASE AORTIC VALVE STENOSIS TAVR PROCEDURE Luis F. Tami, MD Cardiac Cath Lab Director Memorial Regional Hospital 86 yr old CABG 1995. LIMA to LAD and SVG to OM. Presented
TAVR IN INTERMEDIATE-RISK PATIENTS
TAVR IN INTERMEDIATE-RISK PATIENTS K. Lampropoulos MD, PhD, FESC, MEAPCI Interventional Cardiologist Evangelismos General Hospital The Burden of Valve Disease Prevalence Survival NATURAL HISTORY OF AS
Transcatheter Aortic Valve Implantation (TAVI)
Transcatheter Aortic Valve Implantation (TAVI) QEH Registry A Multidisciplinary Team Approach Michael KY Lee 1, LK Chan 1, KC Chan 1, KT Chan 1, SF Chui 1, HS Ma 1, CY Wong 1, CS Chiang 1, P Li 1, CB Lam
Transcatheter Aortic Valve Replacement TAVR
Transcatheter Aortic Valve Replacement TAVR Paul Gordon, MD Associate Prof of Medicine, Brown University Director, Cardiac Catheterization Laboratory The Miriam Hospital Disclosures: none 100 Symptomatic
SAPIEN 3: Evaluation of a Balloon- Expandable Transcatheter Aortic Valve in High-Risk and Inoperable Patients With Aortic Stenosis One-Year Outcomes
SAPIEN 3: Evaluation of a Balloon- Expandable Transcatheter Aortic Valve in High-Risk and Inoperable Patients With Aortic Stenosis One-Year Outcomes Howard C. Herrmann, MD on behalf of The PARTNER II Trial
LOW RISK TAVR. WHAT THE FUTURE HOLDS
LOW RISK TAVR. WHAT THE FUTURE HOLDS Michael J. Reardon, M.D. Professor of Cardiothoracic Surgery Allison Family Distinguish Chair of Cardiovascular Research Houston Methodist DeBakey Heart & Vascular
Peri-operative results and complications in 15,964 transcatheter aortic valve implantations from the German Aortic valve RegistrY (GARY)
Peri-operative results and complications in 15,964 transcatheter aortic valve implantations from the German Aortic valve RegistrY (GARY) Thomas Walther, Christian W. Hamm, Gerhard Schuler, Alexander Berkowitsch,
Neal Kleiman, MD Houston Methodist DeBakey Heart and Vascular Institute
Neal Kleiman, MD Houston Methodist DeBakey Heart and Vascular Institute Despite a 33 fold growth in the first five years, there is still tremendous variability among penetration in different countries
RANDOMISED TRIALS TAVI WITH SAVR STEPHAN WINDECKER AORTIC VALVE DISEASE COMPARING
AORTIC VALVE DISEASE RANDOMISED TRIALS COMPARING TAVI WITH SAVR STEPHAN WINDECKER DEPARTMENT OF CARDIOLOGY SWISS CARDIOVASCULAR CENTER AND CLINICAL TRIALS UNIT BERN BERN UNIVERSITY HOSPITAL, SWITZERLAND
TRANSCATHETER AORTIC VALVE IMPLANTATION: PSCC EXPERIENCE DR HUSSEIN ALAMRI PSCC RIYADH
TRANSCATHETER AORTIC VALVE IMPLANTATION: PSCC EXPERIENCE DR HUSSEIN ALAMRI PSCC RIYADH Available systems: Edwards (TA and TF) and Core valve. INTRODUCTION 3 4% 0f > 65 y. 30 40% of elderly denied surgery,.
TAVI in Korea, How to Avoid Conduction
TAVI in Korea, How to Avoid Conduction Disturbance after CoreValve Seung-Jung Park, MD, PhD Professor of Medicine, University of Ulsan College of Medicine, Heart Institute, Asan Medical Center, Seoul,
Ian T. Meredith AM. MBBS, PhD, FRACP, FCSANZ, FACC, FAPSIC. Monash HEART, Monash Health & Monash University Melbourne, Australia
Two-Year Outcomes With the Fully Repositionable and Retrievable Lotus Transcatheter Aortic Replacement Valve in 120 High-Risk Surgical Patients With Severe Aortic Stenosis: Results From the REPRISE II
2/15/2018 DISCLOSURES OBJECTIVES. Consultant for BioSense Webster, a J&J Co. Aortic stenosis background. Short history of TAVR
TRANSCATHETER AORTIC VALVE REPLACEMENT IN 2018: IS IT NOW THE STANDARD OF CARE? 22 ND ANNUAL COASTAL CARDIAC & VASCULAR CONFERENCE FEBRUARY 17, 2018 R. David Anderson, MD, MS, FACC, FSCAI Professor of
Prosthesis-Patient Mismatch in High Risk Patients with Severe Aortic Stenosis in a Randomized Trial of a Self-Expanding Prosthesis
Prosthesis-Patient Mismatch in High Risk Patients with Severe Aortic Stenosis in a Randomized Trial of a Self-Expanding Prosthesis George L. Zorn, III On Behalf of the CoreValve US Clinical Investigators
Edwards Lifesciences 2011 Investor Conference 12/9/2011
Edwards Lifesciences 2011 Investor Conference EDWARDS LIFESCIENCES Transcatheter Heart Valves Larry L. Wood Corporate Vice President, Transcatheter Valve Replacement 2 1 Edwards Lifesciences 2011 Investor
Summary Transcatheter aortic valve implantation: Evaluation of the evidence and synthesis of organizational issues
ETMIS 2012 ; Vol. 8 : N 0 8 Summary Transcatheter aortic valve implantation: Evaluation of the evidence and synthesis of organizational issues May 2012 A production of the Institut national d excellence
From Dream to Reality. The PVT Story
From Dream to Reality The PVT Story the Israeli connection Stan Rabinovich Vice President, Discovery Advanced Technology Aortic Stenosis December 14, 2015 The PVT Story at ICI 2015 2 Aortic Stenosis SEVERE
Treatment of Bio-Prosthetic Valve Deterioration Using Transcatheter Techniques
Treatment of Bio-Prosthetic Valve Deterioration Using Transcatheter Techniques Pablo Codner, Abid Assali, Hanna Vaknin-Assa, Katia Orvin, Ram Sharony, Leor Perl, Gabriel Greenberg, Marina Kupershmidt,
Transcatheter Mitral Valve Replacement How Close Are We?
Transcatheter Mitral Valve Replacement How Close Are We? Gregory Pavlides, MD, PhD, FACC, FESC Professor of Medicine Miscia Chair of Interventional Cardiology Director, Cardiac Catheterization Laboratories,
Are Heart Valve Referral Centers Feasible in Latin America?
Are Heart Valve Referral Centers Feasible in Latin America? Vadim Kotowicz, MD Chief of Cardiovascular Surgery Department Italian Hospital of Buenos Aires Disclosure Medtronic inc. Consultanting Johnson
Transcatheter Aortic Valve Implantation (TAVI): Current Evidence
Transcatheter Aortic Valve Implantation (TAVI): Current Evidence Davy C. H. Cheng, MD MSc FRCPC FCAHS CCPE Distinguished University Professor & Chair / Chief Department of Anesthesia & Perioperative Medicine
Measuring the risk in valve patients Lessons learnt from the TAVI story? Bernard Iung Bichat Hospital, Paris, France
Measuring the risk in valve patients Lessons learnt from the TAVI story? Bernard Iung Bichat Hospital, Paris, France Faculty disclosure Bernard Iung I disclose the following financial relationships: Consultant
Bioprosthetic Mitral Valve Dysfunction: Innovation and Evolution of a New Therapeutic Technique
Bioprosthetic Mitral Valve Dysfunction: Innovation and Evolution of a New Therapeutic Technique Charanjit S. Rihal MD MBA Professor and Chair Division of Cardiovascular Diseases Mayo Clinic DISCLOSURES
Transcatheter aortic valve implantation and pre-procedural risk assesment
Transcatheter aortic valve implantation and pre-procedural risk assesment Alec Vahanian,FESC, FRCP(Edin.) Bichat Hospital University Paris VII, Paris, France Disclosures Relationship with companies who
Transcatheter Aortic Valve Implantation (TAVI) for Treatment of Aortic Valve Stenosis Part A
Transcatheter Aortic Valve Implantation (TAVI) for Treatment of Aortic Valve Stenosis Part A S Sehatzadeh, K Kaulback 2009 Suggested Citation Sehatzadeh S, Kaulback K. Transcatheter aortic valve implantation
FRANCE 2 : FRench Aor$c Na$onal Corevalve
: FRench Aor$c Na$onal Corevalve and Edwards Registry Mar$ne Gilard, MD University of Brest, France On behalf of the scien/fic commi2ee and the inves/gators M Laskar, P Donzeau- Gouge, K Chevreul, H Eltchaninoff,