Heart Transplantation & MCS in 2017 Advances & Challenges
|
|
|
- Letitia Butler
- 5 years ago
- Views:
Transcription
1 Heart Transplantation & MCS in 2017 Advances & Challenges Steven Tsui Papworth Hospital, Cambridge, UK
2 Papworth Hospital Heart Transplantation ADVANCES AND CHALLENGES
3
4 Heart Transplants
5 Adult Heart Transplants Kaplan Meier Survival by Era (Transplants: January 1982 June 2014) (N=21,391) (N=39,913) (N=24,485) /2014 (N=20,577) Survival (%) All pair wise comparisons were significant at p < Median survival (years): =8.5; =10.4; =11.9; /2014=NA Years 2016 JHLT Oct; 35(10):
6 Papworth Transplant Service (Apr 2006 Mar 2016, N=320) Heart transplantation: 30 day survival: 95.2% 1 year survival: 90.0% 5 year survival: 81.1% Lung transplantation: 90 day survival: 92.8% 1 year survival: 84.2% 5 year survival: 62.4%
7 EUROTRANSPLANT: Heart Transplant Waiting List & Activity
8 KIDNEY LIVER PANCREAS LUNG HEART
9 How To Increase Heart Transplants? 1. From existing donors DBD a. Increase consent rate b. Increase donor heart utilisation 2. From new donor pool DCD
10 Cardiothoracic Retrieval Team Scout Programme In brain stem dead donors consented for organ donation, cardiothoracic retrieval team travels to donor hospital ICU and performs: Donor assessment Donor optimisation Inclusion criteria DBD Donors y.o. No previous history of ischaemic heart disease Within 2 hrs road travel from retrieval team Consent for organ donation is available
11 Cardiothoracic Retrieval Team Scout Programme 1. Lines, fluids and drugs 2. Cardiac output monitor 3. Flexible bronchoscope 4. Trans oesophageal echo aim to minimise donor ICU resource use..
12 Papworth Scout Experience (Apr 2014 Mar 2016, N=178)
13 Papworth Scout Experience (Apr 2014 Mar 2016, N=178) 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% 9.7% 11.3% 26.4% 24.5% 12.3% 26.4% 47.2% 30.6% Non scouted (N=72) Scouted (N=106) Declined no recipient Declined coronary disease Declined medical history Declined poor function Transplanted
14 UK Donor Heart Utilisation Rate %proceeding heart donors from all possible donors % possible donors p=0.002
15 Post Heart Transplant 30 day Survival Log rank P= OOZ (N=22) Scouted (N=113) N-Scouted (N=34)
16 UK Annual DBD/DCD Donors 2003/04 to 2016/17 Papworth Hospital DBD donors DCD donors
17 Dhital et al. Lancet 2015;385:
18 Papworth Hospital Recondition DCD Heart Ex situ Direct Procurement & Machine Perfusion (DP MP)
19 Messer et al. J Heart Lung Transplant 2016; 35:
20 Recondition DCD Heart In situ Normothermic Regional Perfusion (NRP) Hypoxic arrest 15 min Asystole + 30 min NRP Courtesy of Ayyaz Ali
21 DCD Donor Hearts In situ Assessment After NRP = DBD Pulmonary artery catheter Trans oesophageal Echocardiogram
22 Global Adult DCD Heart Transplant Outcomes Numbers of DCD HTx 30 day survival 1 year survival St. Vincent s, Sydney 14 (DP MP) 100% 100% Harefield, London 5 (DP MP) 80% 60% Papworth, Cambridge 15 (DP MP) +13 (NRP) 100% 100% 80% 100% TOTAL % 89.4%
23 SUMMARY Heart transplant remains best therapy for advanced heart failure Outcomes continue to improve with 5 yr survival exceeding 80% Increase heart transplant activity requires: Improved DBD heart utilisation rate More hospitals to perform DCD heart retrieval
24 Mechanical Circulatory Support ADVANCES AND CHALLENGES
25 INTERMACS REPORT 2016 Q4
26 Actuarial Survival With CF VAD Kirklin et al J Heart Lung Transplant 2015;34:
27 Freedom From Rehospitalisation Kirklin et al J Heart Lung Transplant 2015;34:
28 The Ideal LVAD Papworth Hospital Small size allows atraumatic implant Durable Low adverse event rate: Thrombo resistant Infection resistant TETS? Low shear stress Pulsatility??? Cost effective
29 MOMENTUM 3 Trial N=292 N=292 1:1 randomsation HeartMate 3 N=152 HeartMate II N 142
30
31
32
33 DEVELOPING TECHNOLOGIES?
34 Presented by Dr Jeevanandam at ISHLT 2017
35 Presented by Dr Jeevanandam at ISHLT 2017
36 Presented by Dr Jeevanandam at ISHLT 2017
37
38 SUMMARY LVAD activity overtaken heart transplantation Survival improving but adverse event rates remain unacceptably high New technologies appear promising
39 CONCLUSIONS Advances Record numbers of heart transplants and LVAD implants Outcomes of both therapies continue to improve Challenges Organ shortages accept more DBD hearts and start using DCD hearts MCS adverse events devices being developed to address these problems
Heart Transplant: State of the Art. Dr Nick Banner
Heart Transplant: State of the Art Dr Nick Banner Heart Transplantation What is achieved Current challenges Donor scarcity More complex recipients Long-term limitations Non-specific Pharmacological Immunosuppression
DCD Heart Transplantation Papworth Perspective
DCD Heart Transplantation Papworth Perspective Simon Messer Stephen Large Objectives Heart transplantation in the UK DCD donation in the UK DCD impact on heart function Normothermic Regional Perfusion
lnhs BLOOD AND TRANSPLANT RESEARCH, INNOVATION AND NOVEL TECHNOLOGIES ADVISORY GROUP DCD HEART ACTIVITY
lnhs BLOOD AND TRANSPLANT RESEARCH, INNOVATION AND NOVEL TECHNOLOGIES ADVISORY GROUP INTRODUCTION DCD HEART ACTIVITY 1 DCD heart retrieval began in February 2015 for a 15 month initial evaluation period
32 nd Spanish Co-ordination Congress
32 nd Spanish Co-ordination Congress Santander 19 th October 2017 Stephen Large ma ms mrcp frcs(cth) frcs mba pae(rcp) conflicts of interest 1. TransMedics: halved cost of disposables in one of our experiments
DCD Heart Donation Understanding the Regulatory, Ethical and Clinical Issues. Valluvan Jeevanandam MD University of Chicago Medicine
DCD Heart Donation Understanding the Regulatory, Ethical and Clinical Issues Valluvan Jeevanandam MD University of Chicago Medicine Disclosure Txn None MCS Scientific Advisor Thoratec/Abbott: Chairman
Increasing Organ availability: From Machine Perfusion to Donors after Cardiac Death. Ayyaz Ali
Increasing Organ availability: From Machine Perfusion to Donors after Cardiac Death Ayyaz Ali No relevant financial disclosures 2 Heart Transplantation - Activity 3 Donor Heart Preservation Static preservation
NHS BLOOD AND TRANSPLANT CARDIOTHORACIC ADVISORY GROUP URGENT HEART ALLOCATION SCHEMES 2015/2016 ACTIVITY SUMMARY
INTRODUCTION NHS BLOOD AND TRANSPLANT CARDIOTHORACIC ADVISORY GROUP URGENT HEART ALLOCATION SCHEMES 2015/2016 ACTIVITY SUMMARY 1 This paper is a review of the usage of the Adult Urgent Heart Allocation
Recent Developments in Cardiothoracic Transplantation
Recent Developments in Cardiothoracic Transplantation Sally Rushton Statistics and Clinical Studies NHS Blood and Transplant BTS March 2018 Content Heart and lung transplant activity over last decade Heart
Gabriel C. Oniscu Consultant Transplant Surgeon Honorary Clinical Senior Lecturer NRS Career Research Fellow Royal Infirmary of Edinburgh
Gabriel Oniscu Gabriel C. Oniscu Consultant Transplant Surgeon Honorary Clinical Senior Lecturer NRS Career Research Fellow Royal Infirmary of Edinburgh 50% increase Organ donation Organ retrieval Organ
Disclosures. Normothermic Machine Liver Perfusion
Disclosures Normothermic Machine Liver Perfusion I have nothing to disclose Garrett R. Roll, MD Assistant Professor of Surgery Overview Define normothermic machine liver perfusion (NMLP) Show device examples
SCOMPENSO CARDIACO AVANZATO Controversia: che fine sta facendo il trapianto cardiaco, è sempre la prima opzione?
University of Pavia School of Medicine San Matteo Hospital, Division of Cardiac Surgery Pavia, Italy Prof. Andrea M. D Armini, M.D. SCOMPENSO CARDIACO AVANZATO Controversia: che fine sta facendo il trapianto
U.S. changes in Kidney Allocation
U.S. changes in Kidney Allocation Match kidneys with longest survival to patients with longest survival No parallel matching for kidneys with lower survival potential Decrease discard of kidneys with lower
Current approaches in retrieval and heart preservation
Keynote Lecture Series Current approaches in retrieval and heart preservation Maria Monteagudo Vela, Diana García Sáez, Andre R. Simon Department of Cardiothoracic Transplantation and Mechanical Circulatory
Heart Transplantation
Heart Transplantation Age and Outcome Mayo Clinic Richard Daly, MD Professor of Surgery Surgical Director Heart & Lung Transplantation 2014 MFMER 3346076-1 Rochester, Minnesota 2014 MFMER 3346076-2 The
Heart Transplantation ACC Middle East Conference Dubai UAE October 21, 2017
Heart Transplantation ACC Middle East Conference Dubai UAE October 21, 2017 Randall C Starling MD MPH FACC FAHA FESC FHFSA Professor of Medicine Kaufman Center for Heart Failure Department of Cardiovascular
Heart Failure Medical and Surgical Treatment
Heart Failure Medical and Surgical Treatment Daniel S. Yip, M.D. Medical Director, Heart Failure and Transplantation Mayo Clinic Second Annual Lakeland Regional Health Cardiovascular Symposium February
Who and When to Refer for a Heart Transplant
Who and When to Refer for a Heart Transplant Dr Jayan Parameshwar Consultant Cardiologist Papworth Hospital BSH 24 th November 2017 BSH Annual Autumn Meeting 2017 Presentation title: Who and when to refer
Mechanical Circulatory Support in the Management of Heart Failure
Mechanical Circulatory Support in the Management of Heart Failure Feras Bader, MD, MS, FACC Associate Professor of Medicine Director, Heart Failure and Transplant Cleveland Clinic Abu Dhabi Chairman, Heart
Mechanical assist patient selection, device selection, and outcomes
Mechanical assist patient selection, device selection, and outcomes Josef Stehlik, MD, MPH Associate Professor of Medicine Medical Director, Heart Transplant Program University of Utah School of Medicine
University of Pittsburgh Critical Care Medicine
University of Pittsburgh Critical Care Medicine www.ccm.pitt.edu Intensivist-led Donor Care in the Intensive Care Unit Raghavan Murugan MD, MS, FRCP Assistant Professor Dept. of Critical Care Medicine
Organ perfusion prior to transplantation
Organ perfusion prior to transplantation Benedict Phillips SpR Transplant Surgery Research Fellow Guy s Hospital, London Introduction Organ perfusion with blood products prior to transplantation is an
Predicting Major Outcomes after MCSD Implant. Risk Factors for Death, Transplant, and Recovery. James Kirklin, MD David Naftel, PhD
Predicting Major Outcomes after MCSD Implant Risk Factors for Death, Transplant, and Recovery James Kirklin, MD David Naftel, PhD 1 I have no financial disclosures (I am the Principle Investigator for
In-situ v Normothermic Regional Perfusion for Abdominal Organs
In-situ v Normothermic Regional Perfusion for Abdominal Organs ANGEL RUIZ M.D. DONATION AND TRANSPLNAT COORDINATION UNIT MEDICAL DIRECTION HOSPITAL CLÍNIC DE BARCELONA Introduction Donation after circulatory
This report has been produced by Statistics and Clinical Audit, NHS Blood and Transplant.
Preface This report has been produced by Statistics and Clinical Audit, NHS Blood and Transplant. All figures quoted in this report are as reported to NHS Blood and Transplant by 17 June 2012 for the UK
Bridge to Heart Transplantation
Bridge to Heart Transplantation Ulf Kjellman MD, PhD Senior Consultant Surgeon Heart Centre KFSH&RC 1 Disclosure Appointed for Proctorship by Thoratec/St.Jude/Abbott 2 To run a full overall covering transplant
Heart Transplantation in Seniors European View
Heart Transplantation in Seniors European View Hynek RIHA Department of Anesthesiology and Intensive Care Institute for Clinical and Experimental Medicine Prague, Czech Republic 3 rd Int l Symposium: Perioperative
Transplant in Pediatric Heart Failure
Transplant in Pediatric Heart Failure Francis Fynn-Thompson, MD Co-Director, Center for Airway Disorders Surgical Director, Pediatric Mechanical Support Program Surgical Director, Heart and Lung Transplantation
Utilisation of an embedded specialist nurse and collaborative care pathway increases potential organ donor referrals in the emergency department
1 Norfolk and Norwich University Hospital NHS Trust, Norwich, Norfolk, UK 2 NHS Blood and Transplant, Addenbrookes Hospital, Cambridge, UK Correspondence to Dr Julian Garside, Emergency Medicine Registrar,
TRANSPLANTS The Gift of Life. Boris L. Gala-Lopez. MD, MSc, PhD Multi-Organ Transplant Surgeon
TRANSPLANTS The Gift of Life Boris L. Gala-Lopez. MD, MSc, PhD Multi-Organ Transplant Surgeon Disclosure I, Boris Gala-Lopez declare that in the past 3 years: I have received manufacturer funding from
Spanish model of kidney transplantation and organ donation
Spanish model of kidney transplantation and organ donation JM.Campistol, Nephrology and Renal Transplant Department, Hospital Clinic, University of Barcelona, Barcelona, Spain. jmcampis@clinic.ub.es SPAIN
Translating Device and Mechanical Support Guidelines to ACHD Research. Timothy M. Maul, CCP, PhD Perfusionist Sr. Research Scientist
Translating Device and Mechanical Support Guidelines to ACHD Research Timothy M. Maul, CCP, PhD Perfusionist Sr. Research Scientist Disclosures No financial disclosures May discuss off-label or investigational
This report has been produced by Statistics and Clinical Audit, NHS Blood and Transplant.
Preface This report has been produced by Statistics and Clinical Audit, NHS Blood and Transplant. All figures quoted in this report are as reported to NHS Blood and Transplant by 20 May 2013 for the UK
Organ Donation Activity
3 Organ Donation Activity Organ Donation Activity Key messages There has been a 11% increase in deceased donors (to 1,574) and a
Consent and donor choice in lung and heart-lung transplantation
Consent and donor choice in lung and heart-lung transplantation A patient s guide 1 Lung transplantation is a good option for carefully selected patients with end stage lung disease but sadly there is
Marcelo Cypel MD MSc
Ex vivo Organ Repair Marcelo Cypel MD MSc Canada Research Chair in Lung Transplantation Surgical Director ECLS Program UHN Assistant Professor of Surgery Division of Thoracic Surgery University Health
Task distribution in organ transplantation The German example
Journalist Workshop on organ donation & transplantation Introduction to organ donation and transplantation Axel Rahmel, Frankfurt/Main Organized by the European Commission, Directorate General for Health
Lessons learned from ENDURANCE, ROADMAP, MedaMACS, and how to go forward?
Lessons learned from ENDURANCE, ROADMAP, MedaMACS, and how to go forward? Mark S. Slaughter, MD Professor and Chair Department of Cardiovascular and Thoracic Surgery University of Louisville What could
Organ quality can be improved
Preservation methods for transplant organs Organ quality can be improved Dr. Markus Quante Prof. Stefan G. Tullius The interval between retrieval and implantation of an organ can be used not only to prevent
Organ Donation and Transplantation in Wales
Organ Donation and Transplantation in Wales How are we doing? Cornea: 119 Lung: 9 Liver: 37 Heart: 12 Kidneys: 127 Pancreas: 4 Small bowel: 0 Number of Transplants in Wales in 2016/17 Report 2016/17 Referrals
Update on Mechanical Circulatory Support. AATS May 5, 2010 Toronto, ON Canada
Update on Mechanical Circulatory Support AATS May 5, 2010 Toronto, ON Canada Disclosures NONE Emergency Circulatory Support ECMO Tandem Heart Impella Assessment Cardiac Function Pulmonary function Valvular
Hypothermic or normothermic abdominal regional perfusion: strategies and selection criteria for NHBD (Systems ECMO)
Hypothermic or normothermic abdominal regional perfusion: strategies and selection criteria for NHBD (Systems ECMO) Constantino Fondevila Associate Professor of Surgery HPB & Liver Transplant Surgery Hospital
The number of patients waiting on the pancreas transplant list fell by 7% during the year, to 252 at 31 March 2015
6 Pancreas Activity Pancreas Activity Key messages The number of patients waiting on the pancreas transplant list fell by 7% during the year, to 252 at 31 March 2015 The number of pancreas donors after
LUNG ALLOCATION SCORE SYSTEM UPDATE
LUNG ALLOCATION SCORE SYSTEM UPDATE Current Lung Allocation System System was implemented on May 4, 25 The Lung Allocation Score (LAS) is based on a combination of Expected survival in next year without
TRANSPLANT ACTIVITY IN THE UK
Activity Report 2010/11 TRANSPLANT ACTIVITY IN THE UK www.nhsbt.nhs.uk PREFACE This report has been produced by Statistics and Clinical Audit, NHS Blood and Transplant. All figures quoted in this report
Summary of Significant Changes. Policy
This Policy replaces POL186/2 Copy Number Effective 01/04/14 Summary of Significant Changes Clarification of policy approval process Paragraph 2.2.1 Clarification of Kidney Fast Track Scheme offering criteria
The number of patients waiting on the pancreas transplant list fell by 1% during the year, to 224 at 31 March 2017
6 Pancreas Activity Pancreas Activity Key messages The number of patients waiting on the pancreas transplant list fell by 1% during the year, to 224 at 31 March 2017 The number of pancreas donors after
Concomitant Aortic Valve Procedures in Patients Undergoing Implantation of Continuous-Flow LVADs: An INTERMACS Database Analysis
Concomitant Aortic Valve Procedures in Patients Undergoing Implantation of Continuous-Flow LVADs: An INTERMACS Database Analysis April 11, 2014 Jason O. Robertson, M.D., M.S.; David C. Naftel, Ph.D., Sunil
Case - Advanced HF and Shock (INTERMACS 1)
Case - Advanced HF and Shock (INTERMACS 1) Navin K. Kapur, MD, FACC, FSCAI, FAHA Associate Professor, Department of Medicine Interventional Cardiology & Advanced Heart Failure Programs Executive Director,
Care of the DCD in ICU: the French experience
Care of the DCD in ICU: the French experience The National Steering Committee of donors after circulatory death C. Antoine 1, M. Videcoq 2, B. Riou 3, D. Dorez 4, G. Cheisson 5, E. Savoye 1,L. Durand 1,
Why Children Are Not Small Adults? Treatment of Pediatric Patients Needing Mechanical Circulatory Support
Why Children Are Not Small Adults? Treatment of Pediatric Patients Needing Mechanical Circulatory Support Utpal S Bhalala, MD, FAAP Assistant Professor and Director of Research Pediatric Critical Care
Advances in Advanced Heart Failure Therapies. Disclosures. Management Algorithm for Patients in Cardiogenic Shock
Advances in Advanced Heart Failure Therapies 9 th Annual Dartmouth Conference on Advances in Heart Failure Therapies Dartmouth-Hitchcock Medical Center May 20, 2013 Joseph G. Rogers, M.D. Associate Professor
Organ preservation & transplantation: newest insights & perspectives. Ina Jochmans, MD, PhD Abdominal Transplant Surgery KU Leuven, Belgium
Organ preservation & transplantation: newest insights & perspectives Ina Jochmans, MD, PhD Abdominal Transplant Surgery KU Leuven, Belgium 1. Expand the donor pool 2. Optimal preservation & resuscitation
Organ Donation and Transplantation data for Black, Asian and Minority Ethnic (BAME) communities. Report for 2017/2018 (1 April March 2018)
Organ Donation and Transplantation data for Black, Asian and Minority Ethnic (BAME) communities Report for 07/0 ( April 0 March 0) CONTENTS EXECUTIVE SUMMARY... INTRODUCTION... ORGAN DONOR REGISTER (ODR)...
Lung Transplantation: Overview and the MUSC Program
Lung Transplantation: Overview and the MUSC Program Timothy P.M. Whelan MD Associate Professor of Medicine Medical Director of Lung Transplantation History of Lung Transplant James Hardy Univ of Mississippi
Update on organ donation in British Columbia
Update on organ donation in British Columbia Jagbir Gill MD MPH FRCPC Associate Professor of Medicine, UBC Vice President, CORR Board 2017 BC Kidney Days October 5, 2017 Canadian Institute for Health Information
Overview of MCS in Bruce B Reid, MD Surgical Director Artificial Heart Program/Heart Transplantation
Overview of MCS in 2017 Bruce B Reid, MD Surgical Director Artificial Heart Program/Heart Transplantation Technology Embracing Progress Technology Adoption Internet Adoption of Technology Pioneer in the
Ventricular Assist Device: Are Early Interventions Superior? Hamang Patel, MD Section of Cardiomyopathy & Heart Transplantation
Ventricular Assist Device: Are Early Interventions Superior? Hamang Patel, MD Section of Cardiomyopathy & Heart Transplantation Objectives Current rationale behind use of MCS Patient Selection Earlier?
How to Develop a Comprehensive Ventricular Assist Device Program
How to Develop a Comprehensive Ventricular Assist Device Program Rodrigo V. González, MD, MS Sección de Cirugía Cardiovascular División de Cirugía Facultad de Medicina Pontificia Universidad Católica de
Surgical Options for Advanced Heart Failure
Surgical Options for Advanced Heart Failure Benjamin Medalion, MD Director, Transplantation and Heart Failure Surgery Department of Cardiothoracic Surgery Rabin Medical Center, Beilinson Hospital Heart
Organ Donation and Transplantation data for Black, Asian and Minority Ethnic (BAME) communities. Report for 2015/2016 (1 April March 2016)
Organ Donation and Transplantation data for Black, Asian and Minority Ethnic (BAME) communities Report for 2015/2016 (1 April 2010 31 March 2016) INTRODUCTION This report provides information related to
Acute Circulatory Support Should We or Shouldn t We?
Acute Circulatory Support Should We or Shouldn t We? Navin K. Kapur, MD, FACC, FSCAI Assistant Professor, Division of Cardiology Director, Acute Circulatory Support Program Director, Interventional Research
Heart Transplant in NZ Challenges and Triumphs
Transplant Update on New Zealand heart transplant programme: challenges and triumphs Cara Wasywich Chairs: Kathy Ferrier & Richard Troughton Heart Transplant in NZ Challenges and Triumphs Cara Wasywich,
The number of patients registered on the kidney transplant list this year fell by 4% from 5,233 to 5,033
5 Kidney Activity Kidney Activity Key messages The number of patients registered on the kidney transplant list this year fell by 4% from 5,233 to 5,033 The number of deceased kidney donors increased by
Optimizing the Donor Lung with EVLP
Optimizing the Donor Lung with EVLP Marcelo Cypel MD MSc FRCSC Canada Research Chair in Lung Transplantation Surgical Director ECLS Lung Program UHN Associate Professor of Surgery Division of Thoracic
The realities of donor heart availability in Australia and NZ
The realities of donor heart availability in Australia and NZ Peter Ruygrok Cardiologist Queenstown, December 2017 Topics to cover Update on NZ heart transplant programme An ACHD recipient story Donor
Chronic renal histological changes at implantation and subsequent deceased donor kidney transplant outcomes: a single-centre analysis
Chronic renal histological changes at implantation and subsequent deceased donor kidney transplant outcomes: a single-centre analysis Benedict Phillips 1, Kerem Atalar 1, Hannah Wilkinson 1, Nicos Kessaris
Understanding the Pediatric Ventricular Assist Device
Understanding the Pediatric Ventricular Assist Device W. James Parks, MSc., MD Pediatric Cardiologist Assistant Professor of Pediatrics and Radiology Children s Healthcare of Atlanta Sibley Heart Center
Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy with HeartMate 3 (MOMENTUM 3) Long Term Outcomes
Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy with (MOMENTUM 3) Long Term Outcomes Mandeep R. Mehra, MD, Daniel J. Goldstein, MD, Nir Uriel, MD, Joseph
A Fully Magnetically Levitated Left Ventricular Assist Device. Final Report of the MOMENTUM 3 Trial
A Fully Magnetically Levitated Left Ventricular Assist Device Final Report of the MOMENTUM 3 Trial Mandeep R. Mehra, MD, Nir Uriel, MD, Joseph C. Cleveland, Jr., MD, Daniel J. Goldstein, MD, National Principal
Disclosures. No disclosures to report
Disclosures No disclosures to report Update on MOMENTUM 3 Trial: The Final Word? Francis D. Pagani MD PhD Otto Gago MD Professor of Cardiac Surgery University of Michigan Ann Arbor, Michigan, USA LVAD
เอกราช อร ยะช ยพาณ ชย
30 July 2016 เอกราช อร ยะช ยพาณ ชย Heart Failure and Transplant Cardiology aekarach.a@chula.ac.th Disclosure Speaker, CME service: Merck, Otsuka, Servier Consultant, non-cme service: Novartis, Menarini
The status of pediatric liver transplantations and waiting list was presented by Ilse Duus Weinreich.
Minutes of the Nordic Pediatric Liver Transplant Group (NPLTG) Meeting Copenhagen October 9 th, 2018 and the Nordic liver Transplant Group (NLTG) meeting October 10 th, 2018 Minutes from pediatric meeting
Mechanical support of the failing heart: Will heart transplantation become obsolete? Charles Lindbergh
William Pierce, MD What ever happened to the artificial heart? Mechanical support of the failing heart: Will heart transplantation become obsolete? Dan M. Meyer, MD The 20 th Annual Donald and Lois Roon
Is it safe to transplant against HLA DSA in cardiothoracic patients? development and implementation of national Guidelines
Is it safe to transplant against HLA DSA in cardiothoracic patients? development and implementation of national Guidelines Dr Martin Howell. Laboratory Director. Department of H&I, NHS Blood and Transplant,
Organ Donation and Transplantation. Activity Report 2015/16
Organ Donation and Transplantation Activity Report 2015/16 Preface This report has been produced by Statistics and Clinical Studies, NHS Blood and Transplant. All figures quoted in this report are as reported
Waiting for a Kidney. Objectives
Waiting for a Kidney Department of Urologic Sciences Grand Rounds William Gourlay Christopher Nguan April 25, 2007 Objectives 1. review the waiting times for deceased-donor kidney transplants in BC and
Left Ventricular Assist Devices (LVADs): Overview and Future Directions
Left Ventricular Assist Devices (LVADs): Overview and Future Directions FATIMA KARAKI, M.D. PGY-3, DEPARTMENT OF MEDICINE WASHINGTON UNIVERSITY IN ST. LOUIS ST. LOUIS, MISSOURI, USA St. Louis, Missouri,
Heart Transplantation is Dead
Heart Transplantation is Dead Alternatives to Transplantation in Heart Failure Sagar Damle, MD University of Colorado Health Sciences Center Grand Rounds September 8, 2008 Outline Why is there a debate?
Heart Donation in Australia and New Zealand
Chapter 7 Heart Donation in Australia and New Zealand 2016 Annual Report Data to 31-Dec-2015 HEART DONATION In 2015, there were 95 heart transplant recipients, including two heart/double lung transplant
United Kingdom Transplant Activity UK Transplant. Every statisticisaperson.
United Kingdom Transplant Activity 2001 UK Transplant Every statisticisaperson. Cover photograph: Caroline and John Fowler s daughter Aimee, now aged two, shared a donated liver in the first operation
The number of patients registered on the kidney transplant list this year fell by 7% from 5686 to 5275
5 Kidney Activity Kidney Activity Key messages The number of patients registered on the kidney transplant list this year fell by 7% from 5686 to 5275 The number of deceased kidney donors increased by 7%
Advancing Organ Donation: can we really make it happen?
Advancing Organ Donation: can we really make it happen? Current Strategy and thoughts out of the box Mr Chris Rudge FRCS National Clinical Director for Transplantation Agenda Current Strategy Is it working?
Advanced Medicine 2016 Lung Transplantation. Paul A Corris Newcastle University Newcastle Upon Tyne UK
Advanced Medicine 2016 Lung Transplantation Paul A Corris Newcastle University Newcastle Upon Tyne UK First Human Lung Transplantation 1963 JAMA 1963;186:1065-74 The lung donor was a NHBD who died from
Mechanical Circulatory Support (MCS): What Every Pharmacist Needs to Know!
Mechanical Circulatory Support (MCS): What Every Pharmacist Needs to Know! Matthew A. Wanat, PharmD, BCPS, BCCCP, FCCM Clinical Assistant Professor University of Houston College of Pharmacy Clinical Pharmacy
How to mend a broken heart: transplantation or LVAD?
SCDU DI CARDIOCHIRURGIA Università degli Studi di Torino Ospedale S. Giovanni Battista Direttore: Prof. Mauro Rinaldi How to mend a broken heart: transplantation or LVAD? Massimo Boffini Mauro Rinaldi
Organ Donation and Transplantation data for Black, Asian and Minority Ethnic (BAME) communities. Report for 2016/2017 (1 April March 2017)
Organ Donation and Transplantation data for Black, Asian and Minority Ethnic (BAME) communities Report for 6/7 ( April March 7) CONTENTS EXECUTIVE SUMMARY... INTRODUCTION... ORGAN DONOR REGISTER (ODR)...
Further devices to treat heart failure
Postgraduate Course Heart Failure Further devices to treat heart failure Pr. Matthias Kirsch Department of Cardiac Surgery Centre Hospitalo-Universitaire Vaudois Université de Lausanne e-mail: matthias.kirsch@chuv.ch
Summary of Significant Changes. Policy
This Policy replaces POL193/6 Copy Number Effective 13/05/16 Summary of Significant Changes Para 1.3.1.6 - Amendment to donor and recipient age match points to reflect the fact that paediatric recipients
The number of patients on the active liver transplant list at 31 March 2017 was 530, a fall of 8% from 2016
8 Liver Activity Liver Activity Key messages The number of patients on the active liver transplant list at 31 March 2017 was 530, a fall of 8% from 2016 The number of liver donors after brain death increased
Extracorporeal membrane oxygenation after lung transplantation: risk factors and outcomes analysis
Featured Article Extracorporeal membrane oxygenation after lung transplantation: risk factors and outcomes analysis Massimo Boffini 1, Erika Simonato 1, Davide Ricci 1, Fabrizio Scalini 1, Matteo Marro
Overview of organ donation and transplantation
BTS Congress, March 2018 Overview of organ donation and transplantation Rachel Johnson Statistics and Clinical Studies NHS Blood and Transplant Organ Donation and Transplantation: the headlines Subject
NHS BLOOD AND TRANSPLANT LIVER ADVISORY GROUP WAITING TIMES AND DEATHS ON THE LIST BY BLOOD GROUP SUMMARY
NHS BLOOD AND TRANSPLANT LIVER ADVISORY GROUP WAITING TIMES AND DEATHS ON THE LIST BY BLOOD GROUP BACKGROUND SUMMARY 1 Restrictions in the allocation of livers were introduced in 2006 to reverse the increasingly
Indications for prolongation of ECMO into the early postoperative period in lung transplantation How we do it
Indications for prolongation of ECMO into the early postoperative period in lung transplantation How we do it W Klepetko, MD Professor of Thoracic Surgery HEAD: DIVISION OF THORACIC SURGERY MEDICAL UNIVERSITY
Paired Donation. Andrew Bradley Rachel Johnson Joanne Allen Susan V Fuggle. Cambridge University NHS Hospitals NHS Foundation trust
Paired Donation Andrew Bradley Rachel Johnson Joanne Allen Susan V Fuggle Cambridge University NHS Hospitals NHS Foundation trust Showing a preference 1860 John Calcott Horsley UK Living Donor kidney transplant
Pediatric Mechanical Circulatory Support (MCS)
Pediatric Mechanical Circulatory Support (MCS) Ivan Wilmot, MD Heart Failure, Transplant, MCS Assistant Professor The Heart Institute Cincinnati Children s Hospital Medical Center The University of Cincinnati
Time to death after withdrawal of treatment in donation after circulatory death (DCD) donors
REVIEW C URRENT OPINION Time to death after withdrawal of treatment in donation after circulatory death (DCD) donors J.A. Bradley, G.J. Pettigrew, and C.J. Watson Purpose Controlled donation after circulatory
OPTN/UNOS-Thoracic Organ Transplantation Committee: Proposed Modifications to Adult Heart Allocation
OPTN/UNOS-Thoracic Organ Transplantation Committee: Proposed Modifications to Adult Heart Allocation What problems is the proposal attempting to solve? Each zone = 500 mile radius Heart and Lung Allocation
The Japanese Organ Transplant Act came into effect
298 FUKUSHIMA N et al. Circ J 2017; 81: 298 303 doi: 10.1253/circj.CJ-16-0976 REPORT OF HEART TRANSPLANTATION IN JAPAN Registry Report on Heart Transplantation in Japan (June 2016) Norihide Fukushima,
Risk Factors for Adverse Outcome after HeartMate II Jennifer Cowger, MD, MS St. Vincent Heart Center of Indiana
Risk Factors for Adverse Outcome after HeartMate II Jennifer Cowger, MD, MS St. Vincent Heart Center of Indiana Advanced Heart Failure, Transplant, & Mechanical Circulatory Support Relevant Financial Relationship
Maximizing Donor Lungs: Push and Mend. Amy Pope-Harman, MD. Klassen Research Day. January 22, 2015
Maximizing Donor Lungs: Push and Mend Amy Pope-Harman, MD Klassen Research Day January 22, 2015 Goals Why do we care about donors? Bad things happens to donor lungs Donor criteria history Where we can