Global Transcatheter Mitral Valve Repair and Replacement (TMVR) Market: Analysis By Region, By Country: Opportunities and Forecast ( )

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1 Global Transcatheter Mitral Valve Repair and Replacement (TMVR) Market: Analysis By Region, By Country: Opportunities and Forecast ( ) By Region- North America, Europe, APAC and RoW By Country - United States, Canada, Germany, France, Rest of Europe, Australia, Singapore, Rest of Asia Pacific and Colombia May

2 Table of Content S.No Particulars Page No. 1. Research Methodology Executive Summary Strategic Recommendation Development and Commercialization of TMVR Therapies Asia Pacific Region to witness the fastest growth in the market Heart Valve Devices Outlook Transcatheter Mitral Valve Repair and Replacement Outlook Global Transcatheter Mitral Valve Repair and Replacement Market: Growth and Forecast By Value ( ) By Value ( ) 28 2

3 Table of Content S. No Particulars Page No. 7. Global Transcatheter Mitral Valve Repair and Replacement Market: Regional Analysis Global Transcatheter Mitral Valve Repair and Replacement Market, By Region: Breakdown (%) Global Transcatheter Mitral Valve Repair and Replacement Market Size, By Region, 2016 (%) Global Transcatheter Mitral Valve Repair and Replacement Market Size, By Region, 2022 (%) North America Transcatheter Mitral Valve Repair and Replacement Market: An Analysis By Value ( ) By Value ( ) North America Transcatheter Mitral Valve Repair and Replacement Market: Country Analysis (U.S. and Canada) U.S. Transcatheter Mitral Valve Repair and Replacement Market, By Value ( ) Canada Transcatheter Mitral Valve Repair and Replacement Market, By Value ( ) 47 3

4 Table of Content S. No Particulars Page No. 7.4 Europe Transcatheter Mitral Valve Repair and Replacement Market: An Analysis By Value ( ) By Value ( ) Europe Transcatheter Mitral Valve Repair and Replacement Market: Country Analysis (Germany, France & Rest of Europe) Germany Transcatheter Mitral Valve Repair and Replacement Market, By Value ( ) France Transcatheter Mitral Valve Repair and Replacement Market, By Value ( ) Rest of Europe Transcatheter Mitral Valve Repair and Replacement Market, By Value ( ) Asia Pacific Transcatheter Mitral Valve Repair and Replacement Market: An Analysis By Value ( ) By Value ( ) APAC Transcatheter Mitral Valve Repair and Replacement Market: Country Analysis (Australia, Singapore and Rest of Asia Pacific) 63 4

5 Table of Content S. No Particulars Page No Australia Transcatheter Mitral Valve Repair and Replacement Market, By Value ( ) Singapore Transcatheter Mitral Valve Repair and Replacement Market, By Value ( ) Rest of Asia Pacific Transcatheter Aortic Valve Replacement Market, By Value ( ) Rest of the World Transcatheter Mitral Valve Repair and Replacement Market: An Analysis By Value ( ) By Value ( ) RoW Transcatheter Mitral Valve Repair and Replacement Market: Country Analysis (Colombia) Colombia Transcatheter Mitral Valve Repair and Replacement Market, By Value ( ) Market Dynamics Global Transcatheter Mitral Valve Repair and Replacement Market Growth Drivers Global Transcatheter Mitral Valve Repair and Replacement Market Restraints 78 5

6 Table of Content S. No Particulars Page No. 9. Market Trends SWOT Analysis Transcatheter Mitral Valve Repair and Replacement Market Competitive Landscape Product Benchmarking of Key Industry Players developing Transcatheter MV Repair Technology, By Type of MR Policy and Regulatory Landscape Company Profiling 97 Edwards Lifesciences Corporation 98 Medtronic Plc 101 Abbott Laboratories 105 Neovasc Inc. 108 Cardiac Dimensions Inc About Us 111 6

7 List of Figures Figure No. Figure Title Page No. Figure 1: Heart Valve Problems and Disease Flowchart 19 Figure 2: Heart Valve Treatment Procedure Flowchart 22 Figure 3: Global Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, (USD Million) 27 Figure 4: Global Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, Forecast, (USD Million) 28 Figure 5: Global TMVR Market, By Types of Mitral Regurgitation (%) 29 Figure 6: Global Population Ages 65 and Above, (% of Total) 34 Figure 7: Global Diabetic Population, By Region, 2015 (Million) 34 Figure 8: Global Health Expenditure, (% of GDP) 35 Figure 9: Global Transcatheter Mitral Valve Repair and Replacement Market Size, By Region, 2016 (%) 37 Figure 10: Global Transcatheter Mitral Valve Repair and Replacement Market Size, By Region, 2022 (%) 38 Figure 11: North America Transcatheter Mitral Valve Repair and Replacement Market, By Value, (USD Million) 40 Figure 12: North America Transcatheter Mitral Valve Repair and Replacement Market, By Value, Forecast, (USD Million) 41 Figure 13: North America Healthcare Expenditure, (% of GDP) 42 Figure 14: North America Population Ages 65 and above, (% of Total) 42 Figure 15: U.S. Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, (USD Million) 44 Figure 16: U.S. Health Expenditure, (% of GDP) 45 7

8 Figure No. Figure Title Page No. Figure 17: U.S. Population Ages 65 and above, 2014 and Forecast (Million) 45 Figure 18: Canada Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, (USD Million) 47 Figure 19: Europe Transcatheter Mitral Valve Repair and Replacement Market, By Value, (USD Million) 49 Figure 20: Europe Transcatheter Mitral Valve Repair and Replacement Market, By Value, Forecast, (USD Million) 50 Figure 21: EU Health Expenditure Per Capita, (USD) 51 Figure 22: Breakdown of Total Health Expenditure in Europe (%) 51 Figure 23: European Country Population Aged 65 and Above, (% of Total) 52 Figure 24: Germany Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, (USD Million) 54 Figure 25: Germany GDP Per Capita, PPP, (USD) 55 Figure 26: Germany Age Structure Breakdown, (%) 55 Figure 27: France Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, (USD Million) 56 Figure 28: France Age Structure Breakdown, (%) 57 Figure 29: Rest of Europe Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, (USD Million) 58 Figure 30: Asia Pacific Transcatheter Mitral Valve Repair and Replacement Market, By Value, (USD Million) 60 Figure 31: Asia Pacific Transcatheter Mitral Valve Repair and Replacement Market, By Value, Forecast, (USD Million) 61 Figure 32: APAC Healthcare Expenditure Per Capita, (% of GDP) 62 Figure 33: Australia Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, (USD Million) 64 Figure 34: Singapore Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, (USD Million) 65 Figure 35: Rest of Asia Pacific Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, (USD Million) 66 8

9 List of Figures Figure No. Figure Title Page No. Figure 36: Rest of the World Transcatheter Mitral Valve Repair and Replacement Market, By Value, (USD Million) 68 Figure 37: Rest of the World Transcatheter Mitral Valve Repair & Replacement Market, By Value, Forecast, (USD Million) 69 Figure 38: Middle East and North Africa Healthcare Expenditure, (% of GDP) 70 Figure 39: Latin America Healthcare Expenditure, By Country 2014 (% of GDP) 70 Figure 40: Rest of the World Transcatheter Mitral Valve Repair and Replacement Market, By Value, (USD Million) 72 Figure 41: Rest of the World Transcatheter Mitral Valve Repair & Replacement Market, By Value, Forecast, (USD Million) 91 Figure 42: Middle East and North Africa Healthcare Expenditure, (% of GDP) 99 Figure 43: Latin America Healthcare Expenditure, By Country 2014 (% of GDP) 99 Figure 44: Rest of the World Transcatheter Mitral Valve Repair and Replacement Market, By Value, (USD Million) 99 Figure 45: Rest of the World Transcatheter Mitral Valve Repair & Replacement Market, By Value, Forecast, (USD Million) 100 Figure 46: Medtronic Plc Sales, (USD Billion) 102 Figure 47: Medtronic Plc Sales, By Business Group, 2015 (%) 102 Figure 48: Medtronic Plc Sales, By Region, 2015 (%) 102 Figure 49: Medtronic Plc Cardiac & Vascular Business Group Sales Trend, By Business Division (USD Billion) 103 Figure 50: Medtronic Plc Cardiac & Vascular Business Group Sales, By Division 2016 (%) 103 Figure 51: Abbott Laboratories Sales, (USD Billion) 106 Figure 52: Abbott Laboratories Sales, By Business Segment, 2016 (%) 106 Figure 53: Abbott Laboratories Sales, By Region, 2016 (%) 106 Figure 54: Neovasc Inc. Sales, (USD Million) 109 Figure 55: Neovasc Inc. Sales, By Region, 2015 (%) 109 9

10 LIST OF TABLES Table No. Table Title Page No. Table A: Table A: Common Heart Valve Diseases, Symptoms and Causes 20 Table B: Transcatheter Mitral Valve Repair Technology based Devices, By Therapy Type and Approval Status 32 Table C: Transcatheter Mitral Valve Replacement Technology based Devices, By Therapy Type and Approval Status 33 Table D: U.S. Mitral Regurgitation Statistics, Table E: France Healthcare Related Statistics 57 Table F: Product Benchmarking of Key Industry Players developing Transcatheter MV Repair Technology, By Type of MR 87 Table G: Edwards Lifesciences TMVR Related Company Product Approval 100 Table H: Heart Valve Related Company Product Approval 104 Table I: Recent Merger, Acquisitions and Joint Venture Related to Heart Valve Systems 401 Table J: Recent Heart Valve Related Company Product Approval 107 Table K: Recent Merger, Acquisitions and Joint Venture Related to Heart Valve Systems

11 Global Transcatheter Mitral Valve Repair and Replacement (TMVR) Market - Analysis By Region, By Country: Opportunities and Forecast ( ) (By Region - North America, Europe, Asia Pacific, ROW; By Country - U.S., Canada, Germany, France, Australia, Singapore) Scope of the Study g Global Coverage Regional Coverage Country Coverage Region (North America, Europe, APAC and ROW) Country (U.S., Canada, Germany, France, Australia, Singapore and Colombia) Global Coverage Regional Coverage Country Coverage Company Coverage North America U.S. Europe Canada Edward Life Sciences Asia Pacific Germany Medtronic ROW France Abbott Laboratories Global Transcatheter Mitral Australia Neovasc Inc. Valve Repair and Replacement Market By Value ( ) Transcatheter Mitral Valve Singapore Colombia Cardiac Dimensions Inc. Global Transcatheter Mitral Repair and Replacement Market- Valve Repair and Replacement Market By Value ( ) By Value ( ) Transcatheter Mitral Valve Repair and Replacement Market- Transcatheter Mitral Valve Repair and Replacement Market : By Value & (2012- Product Benchmarking Sales Business Overview Product Launches & Recent By Value ( ) 2022) Approvals Merger & Acquisition 11

12 Research Methodology Research Definition Global Transcatheter Mitral Valve Repair & Replacement Market Report comprises of the study of various aspects of TMVR Market. The report assesses the market for the actual period of and for the forecast period of Global Transcatheter Mitral Valve Repair and Replacement Market has been segmented; By Region (North America, Europe, APAC and ROW) and By Country (U.S., Canada, Germany, France, Australia, Singapore and Colombia) Data Analysis and Interpretation Our historic market trend has been figured out by various paid databases which was further triangulated with inputs and insights from industry experts, companies and stakeholders, through primary research (manufacturers, marketing managers, others). Back-of-the-Envelope calculation for the market estimation has been made through proper understanding of the market as well as future business strategies of the companies operating in the market. Azoth Analytics has conducted quantitative as well as qualitative research to gather market insights such as market sizing, market segmentation, recent trends and developments and competitive landscape. Our team has conducted extensive primary surveys by reaching out industry experts across the value chain of the global TMVR market. For Forecasting purpose we have accessed some of the paid databases such as Bloomberg, Reuters, Factiva, Hoovers etc. Companies Contacted: Edwards Lifesciences, Cardiac Dimensions 12

13 Global Transcatheter Mitral Valve Repair and Replacement Market: Growth and Forecast Rising number of patients with mitral valve disorders and increasing adoption rate of minimally invasive procedures for valve repair and replacement are the major growth drivers Figure 3: Global Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, (USD Million) CAGR x% Source: Azoth Analytics Estimates 27

14 Global Transcatheter Mitral Valve Repair and Replacement Market: Growth and Forecast In the forecast period, global TMVR market is projected to advance at a robust CAGR of 34.71%, surpassing a market value of USD 3,529 million, by Figure 4: Global Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, Forecast, (USD Million) CAGR x% Source: Azoth Analytics Estimates 28

15 Global Transcatheter Mitral Valve Repair and Replacement Market: Growth and Forecast Table B: Transcatheter Mitral Valve Repair Technology based Devices, By Therapy Type and Approval Status Device Name Therapy Type Description Approval Status MitraClio (Abbott Vascular) NeoChord DS1000 (Neochord) Carillon Mitral Contour System (Cardiac Dimensions) Mitralign Percutaneous Annuloplasty System (Mitralign) Cardioband TF (Valtech) MitraFlex (TransCardiac) ValCare MV Repair (ValCare) Source: The American Association for Thoracic Surgery 15

16 U.S. Transcatheter Mitral Valve Repair and Replacement Market, By Value Figure 15: U.S. Transcatheter Mitral Valve Repair and Replacement Market Size, By Value, (USD Million) CAGR x% CAGR x% Source: Azoth Analytics Estimates. 16

17 About Azoth Analytics Pvt Ltd. Azoth Analytics is a business research and analytics firm that creates in-depth research reports and provides customized research solutions and consultancy services. Verticals in which Azoth Analytics specializes include healthcare and pharmaceutical, oil and gas, retail, chemicals, automotive, FMCG, food & beverages and technology. Azoth creates comprehensive and in-depth research reports by recording, interpreting and analyzing information. Strategic market sizing and data dredging techniques include secondary research, and primary research (interviews with management personnel and industry experts). Related Reports: Global Heart Valve Devices Market: Analysis By Procedure (Replacement & Repair), Replacement Procedure By Technique (Mechanical, Bioprosthetic & TAVR), Repair Procedure By Technique (Surgical, Balloon Valvuloplasty & TMVR), By Region, By Country ( ): Procedure (Replacement and Repair); Replacement Procedure By Technique (Mechanical, Bioprosthetic, Transcatheter Aortic Valve Replacement (TAVR)), Repair By Technique (Surgical Devices, Balloon Valvuloplasty, Transcatheter Mitral Valve Repair (TMVR)), By Region (North America, Europe, APAC and ROW) and By Country (U.S., Canada, Germany, France, U.K., China, India, Japan, Brazil and Saudi Arabia) Global Biomaterials Market (By Type, By Application, By Region): Opportunities and Forecasts ( ) - (By Material Type Polymer, Ceramic, Metal; By Application - Orthopaedic, Cardiovascular, Plastic Surgery, Wound Care); By Region-North America, Europe, APAC, ROW; By Country US, UK, Germany, Italy, Japan, China, India; Key Players Strategy, Financial Performance) Disclaimer: Azoth Analytics report information is based mainly on interviews and therefore, is subject to fluctuation. Azoth Analytics therefore, takes no responsibility for any incorrect information supplied to us by industry experts, manufacturers or users. Azoth does not warranty the completeness of the information and data. Also, analysis provided in the report are meant for customers internal use only and not for general publication or disclosure to third parties. 17

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